Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA | 0.0025 | 0.008 | 0.01 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0298 | 0.2091 | 1 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0025 | 0.0085 | 0.0402 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0298 | 0.2091 | 1 |
Onchocerca volvulus | 0.0294 | 0.2062 | 1 | |
Trypanosoma cruzi | kinetoplastid kinetochore protein 19, putative | 0.0071 | 0.0424 | 0.1995 |
Echinococcus multilocularis | Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 | 0.0043 | 0.0218 | 0.0934 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0097 | 0.0461 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.006 | 0.0342 | 0.1472 |
Treponema pallidum | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | 0.1373 | 1 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0288 | 0.2021 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.006 | 0.0342 | 0.1658 |
Echinococcus multilocularis | tumor protein p63 | 0.0328 | 0.2309 | 1 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0157 | 0.1054 | 0.1459 |
Brugia malayi | Ubiquitin carboxyl-terminal hydrolase family protein | 0.0043 | 0.0218 | 0.1046 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0071 | 0.0424 | 0.2065 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0015 | 0.006 |
Mycobacterium tuberculosis | Probable UDP-N-acetylglucosamine 1-carboxyvinyltransferase MurA | 0.0986 | 0.7153 | 1 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0015 | 0.0012 | 0.0045 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0015 | 0.0012 | 0.0019 |
Schistosoma mansoni | thyroid hormone receptor | 0.003 | 0.0118 | 0.1034 |
Trypanosoma cruzi | STE group serine/threonine-protein kinase, putative | 0.0016 | 0.0016 | 0.0038 |
Leishmania major | mitochondrial DNA polymerase beta | 0.0298 | 0.2091 | 1 |
Onchocerca volvulus | Chorion peroxidase homolog | 0.0027 | 0.0097 | 0.0461 |
Echinococcus granulosus | FTZ F1 alpha | 0.003 | 0.0118 | 0.0499 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.003 | 0.0118 | 0.0559 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.003 | 0.0118 | 0.0559 |
Mycobacterium ulcerans | hypothetical protein | 0.0157 | 0.1054 | 0.1043 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.003 | 0.0118 | 0.0559 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.006 | 0.0342 | 0.1602 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.003 | 0.0118 | 0.0559 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD | 0.0025 | 0.008 | 0.01 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0019 | 0.0036 | 0.0163 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0015 | 0.0012 | 0.0048 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsB | 0.0019 | 0.0041 | 0.0029 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0015 | 0.0012 | 0.0047 |
Trichomonas vaginalis | CMGC family protein kinase | 0.006 | 0.0342 | 0.1658 |
Echinococcus multilocularis | 0.007 | 0.0416 | 0.1793 | |
Mycobacterium leprae | Probable fructose bisphosphate aldolase Fba | 0.0141 | 0.0936 | 0.1298 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0027 | 0.0097 | 0.0461 |
Schistosoma mansoni | ubiquitin-specific peptidase 2 (C19 family) | 0.0043 | 0.0218 | 0.1934 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0288 | 0.2021 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 0.1116 | 1 |
Trypanosoma cruzi | STE/STE11 serine/threonine-protein kinase, putative | 0.0016 | 0.0016 | 0.0038 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0027 | 0.0097 | 0.0461 |
Brugia malayi | Cytochrome P450 family protein | 0.0019 | 0.0036 | 0.0163 |
Brugia malayi | AMP-binding enzyme family protein | 0.0025 | 0.0085 | 0.0402 |
Plasmodium falciparum | protein serine/threonine kinase-1 | 0.0071 | 0.0424 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.003 | 0.0118 | 0.0559 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB | 0.0019 | 0.0041 | 0.0046 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.006 | 0.0342 | 0.1586 |
Trichomonas vaginalis | CMGC family protein kinase | 0.006 | 0.0342 | 0.1658 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0097 | 0.0461 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.003 | 0.0118 | 0.0499 |
Schistosoma mansoni | peroxidasin | 0.0027 | 0.0097 | 0.0853 |
Mycobacterium ulcerans | thioesterase TesA | 0.0023 | 0.0065 | 0.0053 |
Onchocerca volvulus | 0.0032 | 0.0132 | 0.0628 | |
Echinococcus granulosus | tumor protein p63 | 0.0328 | 0.2309 | 1 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0015 | 0.0012 | 0.0088 |
Echinococcus multilocularis | aryl hydrocarbon receptor | 0.0015 | 0.0008 | 0.0026 |
Brugia malayi | Animal haem peroxidase family protein | 0.0027 | 0.0097 | 0.0461 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.006 | 0.0342 | 0.1472 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0255 | 0.1227 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0042 | 0.0208 | 0.0957 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.003 | 0.0118 | 0.0499 |
Brugia malayi | hypothetical protein | 0.0016 | 0.0015 | 0.006 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0288 | 0.2021 | 1 |
Trichomonas vaginalis | Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase | 0.0043 | 0.0218 | 0.1041 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0097 | 0.0461 |
Giardia lamblia | Kinase, CMGC MAPK | 0.006 | 0.0342 | 0.0689 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0015 | 0.0012 | 0.0047 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.003 | 0.0118 | 0.0559 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.003 | 0.0118 | 0.0559 |
Mycobacterium ulcerans | 3-phosphoshikimate 1-carboxyvinyltransferase | 0.0387 | 0.2747 | 0.2738 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0015 | 0.006 |
Brugia malayi | hypothetical protein | 0.0027 | 0.0097 | 0.0461 |
Mycobacterium leprae | probable 3-phosphoshikimate 1-carboxyvinyl transferase AroA (5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE SYNTHASE) (EPSP SYNTHASE) (EPSPS | 0.0387 | 0.2747 | 0.3833 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0288 | 0.2021 | 1 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.003 | 0.0118 | 0.0499 |
Mycobacterium ulcerans | polyketide synthase Pks13 | 0.0038 | 0.0178 | 0.0166 |
Brugia malayi | Pax transcription factor protein 2 | 0.0233 | 0.1616 | 0.7834 |
Echinococcus granulosus | hypothetical protein | 0.007 | 0.0416 | 0.1793 |
Brugia malayi | ecdysteroid receptor | 0.003 | 0.0118 | 0.0559 |
Schistosoma mansoni | intermediate filament proteins | 0.0032 | 0.0132 | 0.116 |
Schistosoma mansoni | ubiquitin-specific peptidase 8 (C19 family) | 0.0043 | 0.0218 | 0.1934 |
Echinococcus multilocularis | peroxidasin | 0.0027 | 0.0097 | 0.0412 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.006 | 0.0342 | 0.1602 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.003 | 0.0118 | 0.0559 |
Brugia malayi | Isocitrate dehydrogenase | 0.0015 | 0.0012 | 0.0048 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0097 | 0.0461 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0012 | 0.0087 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0016 | 0.0015 | 0.0111 |
Brugia malayi | hypothetical protein | 0.0016 | 0.0015 | 0.006 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0097 | 0.0461 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0015 | 0.0012 | 0.0019 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0288 | 0.2021 | 1 |
Echinococcus granulosus | geminin | 0.0165 | 0.1116 | 0.4828 |
Brugia malayi | Animal haem peroxidase family protein | 0.0027 | 0.0097 | 0.0461 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0019 | 0.0036 | 0.0132 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.006 | 0.0342 | 0.1649 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE | 0.0015 | 0.0013 | 0.0006 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.006 | 0.0342 | 0.1245 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0019 | 0.0036 | 0.0163 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.003 | 0.0118 | 0.0559 |
Schistosoma mansoni | peroxidasin | 0.0027 | 0.0097 | 0.0853 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0141 | 0.0937 | 0.4458 |
Onchocerca volvulus | 0.0048 | 0.0252 | 0.1213 | |
Onchocerca volvulus | 0.0047 | 0.0245 | 0.118 | |
Echinococcus granulosus | aryl hydrocarbon receptor | 0.0015 | 0.0008 | 0.0026 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0015 | 0.0012 | 0.0043 |
Onchocerca volvulus | 0.0015 | 0.0008 | 0.0029 | |
Brugia malayi | Beta-ketoacyl synthase, N-terminal domain containing protein | 0.0025 | 0.008 | 0.0376 |
Trypanosoma cruzi | kinetoplastid kinetochore protein 10, putative | 0.0071 | 0.0424 | 0.1995 |
Brugia malayi | MAP kinase sur-1 | 0.006 | 0.0342 | 0.1649 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.003 | 0.0118 | 0.0559 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.0141 | 0.0937 | 0.4458 |
Mycobacterium ulcerans | putative regulatory protein | 0.0042 | 0.0209 | 0.0197 |
Wolbachia endosymbiont of Brugia malayi | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | 0.1373 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0118 | 0.0559 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.003 | 0.0118 | 0.0499 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0118 | 0.0559 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0016 | 0.0015 | 0.0053 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.003 | 0.0118 | 0.1034 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0019 | 0.0036 | 0.0132 |
Loa Loa (eye worm) | pax transcription factor protein 2 | 0.0233 | 0.1616 | 0.7834 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0017 | 0.0024 | 0.0104 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0032 | 0.0132 | 0.0628 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks1 | 0.0019 | 0.0042 | 0.0042 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsA | 0.0025 | 0.008 | 0.0095 |
Trypanosoma cruzi | STE group serine/threonine-protein kinase, putative | 0.0016 | 0.0016 | 0.0038 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.003 | 0.0118 | 0.0499 |
Brugia malayi | bHLH-PAS transcription factor | 0.0042 | 0.0209 | 0.1005 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0008 | 0.0029 |
Leishmania major | ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative | 0.0043 | 0.0218 | 0.1006 |
Loa Loa (eye worm) | hypoxia-induced factor 1 | 0.0176 | 0.1195 | 0.5791 |
Brugia malayi | nuclear receptor RXR | 0.0016 | 0.0015 | 0.006 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0016 | 0.0015 | 0.0111 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0015 | 0.0012 | 0.0047 |
Mycobacterium leprae | Polyketide synthase Pks13 | 0.0038 | 0.0178 | 0.0238 |
Brugia malayi | Cytochrome P450 family protein | 0.0019 | 0.0036 | 0.0163 |
Loa Loa (eye worm) | intermediate filament protein | 0.0032 | 0.0132 | 0.0628 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0097 | 0.0461 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0016 | 0.0015 | 0.006 |
Onchocerca volvulus | 0.0027 | 0.0097 | 0.0461 | |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0033 | 0.0143 | 0.0681 |
Echinococcus granulosus | GPCR family 2 | 0.0015 | 0.0012 | 0.0042 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0143 | 0.1259 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks7 | 0.0026 | 0.0092 | 0.0112 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0218 | 0.1046 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.003 | 0.0118 | 0.0559 |
Onchocerca volvulus | Dual oxidase homolog | 0.0027 | 0.0097 | 0.0461 |
Echinococcus multilocularis | musashi | 0.0032 | 0.0132 | 0.056 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.0141 | 0.0936 | 0.0924 |
Mycobacterium tuberculosis | Polyketide synthase Pks12 | 0.0026 | 0.0092 | 0.0112 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.003 | 0.0118 | 0.1034 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.006 | 0.0342 | 0.1602 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.003 | 0.0118 | 0.1034 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0019 | 0.0036 | 0.0163 |
Echinococcus multilocularis | lamin dm0 | 0.0032 | 0.0132 | 0.056 |
Echinococcus multilocularis | geminin | 0.0165 | 0.1116 | 0.4828 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsC | 0.0026 | 0.0092 | 0.008 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsD | 0.0025 | 0.008 | 0.0067 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.003 | 0.0118 | 0.0559 |
Mycobacterium ulcerans | polyketide synthase | 0.0026 | 0.0092 | 0.008 |
Loa Loa (eye worm) | CMGC/CLK protein kinase | 0.0071 | 0.0424 | 0.2046 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0118 | 0.0559 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0042 | 0.0208 | 0.0957 |
Chlamydia trachomatis | phosphoshikimate 1-carboxyl vinyltransferase | 0.0387 | 0.2747 | 0.2741 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0132 | 0.0628 |
Mycobacterium leprae | Probable polyketide synthase Pks1 | 0.0026 | 0.0092 | 0.0117 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.006 | 0.0342 | 0.1472 |
Trichomonas vaginalis | Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase | 0.0043 | 0.0218 | 0.1041 |
Brugia malayi | PAS domain containing protein | 0.0057 | 0.0318 | 0.1533 |
Mycobacterium ulcerans | polyketide synthase | 0.0025 | 0.008 | 0.0067 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0048 | 0.0255 | 0.1227 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0012 | 0.0087 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0048 | 0.0252 | 0.2244 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsC | 0.0025 | 0.008 | 0.0095 |
Brugia malayi | hypothetical protein | 0.0294 | 0.2062 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0118 | 0.0559 |
Loa Loa (eye worm) | blistered cuticle protein 3 | 0.0027 | 0.0097 | 0.0461 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0015 | 0.006 |
Loa Loa (eye worm) | hypothetical protein | 0.0294 | 0.2062 | 1 |
Toxoplasma gondii | type I fatty acid synthase, putative | 0.0026 | 0.0092 | 0.0336 |
Brugia malayi | Animal haem peroxidase family protein | 0.0027 | 0.0097 | 0.0461 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0097 | 0.0461 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0007 | 0.0024 |
Echinococcus granulosus | mitogen activated protein kinase | 0.006 | 0.0342 | 0.1472 |
Trypanosoma cruzi | ubiquitin carboxyl-terminal hydrolase, putative | 0.0043 | 0.0218 | 0.1006 |
Trypanosoma brucei | ubiquitin carboxyl-terminal hydrolase, putative | 0.0043 | 0.0218 | 0.0989 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0012 | 0.0087 |
Onchocerca volvulus | 0.0032 | 0.0132 | 0.0628 | |
Onchocerca volvulus | 0.0027 | 0.0097 | 0.0461 | |
Schistosoma mansoni | retinoic acid receptor RXR | 0.003 | 0.0118 | 0.1034 |
Brugia malayi | hypothetical protein | 0.0191 | 0.1304 | 0.632 |
Trypanosoma cruzi | kinetoplastid kinetochore protein 10, putative | 0.0071 | 0.0424 | 0.1995 |
Echinococcus granulosus | lamin | 0.0032 | 0.0132 | 0.056 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks5 | 0.0026 | 0.0092 | 0.0112 |
Trypanosoma brucei | kinetoplastid kinetochore protein 10 | 0.0071 | 0.0424 | 0.198 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.003 | 0.0118 | 0.0499 |
Trypanosoma brucei | cytochrome P450, putative | 0.0019 | 0.0036 | 0.0114 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0015 | 0.0012 | 0.0043 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0097 | 0.0461 |
Echinococcus granulosus | dual specificity protein kinase clk2 | 0.0071 | 0.0424 | 0.1827 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 0.1116 | 1 |
Mycobacterium tuberculosis | Probable multifunctional mycocerosic acid synthase membrane-associated Mas | 0.0026 | 0.0092 | 0.0112 |
Mycobacterium ulcerans | multifunctional mycocerosic acid synthase membrane-associated Mas | 0.0026 | 0.0092 | 0.008 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.003 | 0.0118 | 0.0499 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0127 | 0.0607 |
Brugia malayi | intermediate filament protein | 0.0032 | 0.0132 | 0.0628 |
Schistosoma mansoni | single-minded | 0.0057 | 0.0318 | 0.2836 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.0042 | 0.0208 | 0.094 |
Echinococcus multilocularis | Aryl hydrocarbon receptor nuclear | 0.0015 | 0.0008 | 0.0026 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0071 | 0.0424 | 0.3785 |
Schistosoma mansoni | nuclear hormone receptor | 0.003 | 0.0118 | 0.1034 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0118 | 0.0559 |
Onchocerca volvulus | 0.0027 | 0.0097 | 0.0461 | |
Echinococcus granulosus | peroxidasin | 0.0027 | 0.0097 | 0.0412 |
Echinococcus multilocularis | FTZ F1 alpha | 0.003 | 0.0118 | 0.0499 |
Schistosoma mansoni | serine/threonine protein kinase | 0.006 | 0.0342 | 0.305 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0118 | 0.0559 |
Plasmodium vivax | serine/threonine kinase-1, putative | 0.0071 | 0.0424 | 1 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.006 | 0.0342 | 0.1602 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.0288 | 0.2021 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0288 | 0.2021 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.003 | 0.0118 | 0.0559 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0015 | 0.0012 | 0.0042 |
Onchocerca volvulus | Peroxidase homolog | 0.0027 | 0.0097 | 0.0461 |
Schistosoma mansoni | lamin | 0.0032 | 0.0132 | 0.116 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.003 | 0.0118 | 0.0559 |
Loa Loa (eye worm) | steroid hormone receptor | 0.003 | 0.0118 | 0.0559 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0015 | 0.0012 | 0.0019 |
Echinococcus granulosus | Aryl hydrocarbon receptor nuclear | 0.0015 | 0.0008 | 0.0026 |
Trypanosoma cruzi | kinetoplastid kinetochore protein 19, putative | 0.0071 | 0.0424 | 0.1995 |
Leishmania major | cytochrome p450-like protein | 0.0019 | 0.0036 | 0.0132 |
Onchocerca volvulus | Peroxidase homolog | 0.0027 | 0.0097 | 0.0461 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.003 | 0.0118 | 0.1034 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0097 | 0.0461 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0015 | 0.0012 | 0.0043 |
Trichomonas vaginalis | CMGC family protein kinase | 0.006 | 0.0342 | 0.1658 |
Onchocerca volvulus | Peroxidasin homolog | 0.0027 | 0.0097 | 0.0461 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0025 | 0.008 | 0.0067 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.003 | 0.0118 | 0.0559 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0042 | 0.0208 | 0.0957 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0015 | 0.0012 | 0.0045 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0215 | 0.1032 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0015 | 0.0012 | 0.004 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC | 0.0026 | 0.0092 | 0.0117 |
Schistosoma mansoni | aryl hydrocarbon receptor | 0.0057 | 0.0318 | 0.2836 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0097 | 0.0461 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0015 | 0.0012 | 0.0042 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.003 | 0.0118 | 0.1034 |
Mycobacterium leprae | PROBABLE UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE MURA | 0.0986 | 0.7153 | 1 |
Toxoplasma gondii | shikimate dehydrogenase substrate binding domain-containing protein | 0.0387 | 0.2747 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.003 | 0.0118 | 0.0559 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.003 | 0.0118 | 0.0499 |
Mycobacterium ulcerans | thioesterase | 0.0023 | 0.0065 | 0.0053 |
Brugia malayi | nuclear receptor NHR-88 | 0.003 | 0.0118 | 0.0559 |
Leishmania major | protein kinase, putative | 0.0016 | 0.0016 | 0.0038 |
Onchocerca volvulus | Bile acid receptor homolog | 0.003 | 0.0118 | 0.0559 |
Leishmania major | protein kinase, putative | 0.0016 | 0.0016 | 0.0038 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0015 | 0.0012 | 0.0042 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.003 | 0.0118 | 0.0559 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0015 | 0.0012 | 0.0043 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.003 | 0.0118 | 0.0559 |
Giardia lamblia | Kinase, CMGC CLK | 0.0071 | 0.0424 | 0.1143 |
Echinococcus granulosus | ubiquitin specific protease 41 | 0.0043 | 0.0218 | 0.0934 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0143 | 0.0681 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0027 | 0.0097 | 0.0461 |
Echinococcus multilocularis | lamin | 0.0032 | 0.0132 | 0.056 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0288 | 0.2021 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0097 | 0.0461 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0015 | 0.006 |
Brugia malayi | nuclear hormone receptor | 0.003 | 0.0118 | 0.0559 |
Echinococcus multilocularis | GPCR, family 2 | 0.0015 | 0.0012 | 0.0042 |
Echinococcus multilocularis | ubiquitin specific protease 41 | 0.0043 | 0.0218 | 0.0934 |
Echinococcus multilocularis | ubiquitin carboxyl terminal hydrolase 8 | 0.0043 | 0.0218 | 0.0934 |
Mycobacterium leprae | Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas | 0.0026 | 0.0092 | 0.0117 |
Brugia malayi | Animal haem peroxidase family protein | 0.0027 | 0.0097 | 0.0461 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0288 | 0.2021 | 1 |
Mycobacterium tuberculosis | Probable membrane bound polyketide synthase Pks6 | 0.0038 | 0.0178 | 0.0232 |
Toxoplasma gondii | beta-ketoacyl synthase, N-terminal domain-containing protein | 0.0018 | 0.0028 | 0.0104 |
Mycobacterium tuberculosis | Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) | 0.0025 | 0.0085 | 0.0102 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0027 | 0.0097 | 0.0461 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0016 | 0.0015 | 0.006 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.003 | 0.0118 | 0.0499 |
Toxoplasma gondii | hypothetical protein | 0.0048 | 0.0253 | 0.0921 |
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.0141 | 0.0936 | 0.1293 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsD | 0.0025 | 0.008 | 0.0095 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.003 | 0.0118 | 0.0559 |
Mycobacterium tuberculosis | Polyketide synthase Pks2 | 0.0026 | 0.0092 | 0.0112 |
Trypanosoma cruzi | STE/STE11 serine/threonine-protein kinase, putative | 0.0016 | 0.0016 | 0.0038 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0019 | 0.0036 | 0.0023 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.003 | 0.0118 | 0.0559 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0012 | 0.0045 |
Echinococcus multilocularis | dual specificity protein kinase clk2 | 0.0071 | 0.0424 | 0.1827 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0252 | 0.1213 |
Brugia malayi | oxidoreductase, zinc-binding dehydrogenase family protein | 0.0049 | 0.0258 | 0.124 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0097 | 0.0461 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.003 | 0.0118 | 0.0499 |
Loa Loa (eye worm) | hypothetical protein | 0.0191 | 0.1304 | 0.632 |
Schistosoma mansoni | lamin | 0.0032 | 0.0132 | 0.116 |
Brugia malayi | Animal haem peroxidase family protein | 0.0027 | 0.0097 | 0.0461 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.003 | 0.0118 | 0.1034 |
Loa Loa (eye worm) | fatty acid synthase | 0.0027 | 0.0096 | 0.0453 |
Brugia malayi | isocitrate dehydrogenase | 0.0015 | 0.0012 | 0.0048 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0071 | 0.0424 | 0.3785 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0118 | 0.0559 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsA | 0.0019 | 0.0041 | 0.0029 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0288 | 0.2021 | 1 |
Echinococcus granulosus | intermediate filament protein | 0.0032 | 0.0132 | 0.056 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0012 | 0.0047 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks8 | 0.002 | 0.0044 | 0.0044 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0016 | 0.0015 | 0.006 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0012 | 0.0087 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.003 | 0.0118 | 0.0499 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0288 | 0.2021 | 1 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.003 | 0.0118 | 0.1034 |
Onchocerca volvulus | Fatty acid synthase homolog | 0.0049 | 0.0258 | 0.124 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0097 | 0.0461 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0015 | 0.006 |
Trypanosoma brucei | kinetoplastid kinetochore protein 19 | 0.0071 | 0.0424 | 0.198 |
Brugia malayi | Protein kinase domain containing protein | 0.0071 | 0.0424 | 0.2046 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0007 | 0.0024 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0015 | 0.0012 | 0.004 |
Leishmania major | protein kinase, putative | 0.0071 | 0.0424 | 0.1995 |
Trypanosoma cruzi | ubiquitin carboxyl-terminal hydrolase, putative | 0.0043 | 0.0218 | 0.1006 |
Mycobacterium tuberculosis | Polyketide synthase Pks13 | 0.0038 | 0.0178 | 0.0232 |
Onchocerca volvulus | 0.0042 | 0.0209 | 0.1005 | |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.003 | 0.0118 | 0.1034 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.006 | 0.0342 | 0.1602 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0025 | 0.008 | 0.0067 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0097 | 0.0461 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.003 | 0.0118 | 0.0559 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0015 | 0.0012 | 0.0043 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.003 | 0.0118 | 0.0559 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0015 | 0.0012 | 0.0042 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0298 | 0.2091 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.003 | 0.0118 | 0.1034 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0017 | 0.0024 | 0.0104 |
Onchocerca volvulus | 0.0025 | 0.0085 | 0.0402 | |
Onchocerca volvulus | 0.0233 | 0.1616 | 0.7834 | |
Mycobacterium tuberculosis | Probable thioesterase TesA | 0.0023 | 0.0065 | 0.0074 |
Echinococcus granulosus | ubiquitin carboxyl terminal hydrolase 8 | 0.0043 | 0.0218 | 0.0934 |
Trypanosoma brucei | protein kinase, putative | 0.006 | 0.0342 | 0.1586 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0015 | 0.0012 | 0.0043 |
Toxoplasma gondii | cell-cycle-associated protein kinase CLK, putative | 0.0071 | 0.0424 | 0.1543 |
Mycobacterium leprae | PROBABLE THIOESTERASE TESA | 0.0023 | 0.0065 | 0.0079 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0048 | 0.0255 | 0.1227 |
Toxoplasma gondii | type I fatty acid synthase, putative | 0.0019 | 0.0041 | 0.0149 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.003 | 0.0118 | 0.0559 |
Brugia malayi | Blistered cuticle protein 3 | 0.0027 | 0.0097 | 0.0461 |
Onchocerca volvulus | 0.003 | 0.0118 | 0.0559 | |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0118 | 0.0559 |
Brugia malayi | steroid hormone receptor | 0.003 | 0.0118 | 0.0559 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.003 | 0.0118 | 0.0559 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0025 | 0.008 | 0.0067 |
Loa Loa (eye worm) | aryl Hydrocarbon receptor Associated protein family member | 0.0015 | 0.0008 | 0.0029 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.003 | 0.0118 | 0.0499 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.003 | 0.0118 | 0.0499 |
Echinococcus granulosus | Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 | 0.0043 | 0.0218 | 0.0934 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0048 | 0.0255 | 0.1227 |
Schistosoma mansoni | coup transcription factor | 0.003 | 0.0118 | 0.1034 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0032 | 0.0132 | 0.0628 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0051 | 0.0275 | 0.1281 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.003 | 0.0118 | 0.0499 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0016 | 0.0015 | 0.0053 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0043 | 0.0218 | 0.1041 |
Onchocerca volvulus | Peroxidasin homolog | 0.0027 | 0.0097 | 0.0461 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.003 | 0.0118 | 0.0499 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.003 | 0.0118 | 0.0499 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.0416 | 0.2008 |
Leishmania major | protein kinase, putative | 0.0071 | 0.0424 | 0.1995 |
Brugia malayi | hypoxia-induced factor 1 | 0.0176 | 0.1195 | 0.5791 |
Echinococcus granulosus | lamin dm0 | 0.0032 | 0.0132 | 0.056 |
Echinococcus multilocularis | transfer RNA-Lys | 0.0042 | 0.0209 | 0.0897 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.0141 | 0.0937 | 0.4447 |
Brugia malayi | Peroxidasin | 0.0027 | 0.0097 | 0.0461 |
Mycobacterium ulcerans | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | 0.1373 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.003 | 0.0118 | 0.0559 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.006 | 0.0342 | 0.1602 |
Echinococcus granulosus | single minded 2 | 0.0042 | 0.0209 | 0.0897 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.