Detailed information for compound 1806085

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 428.311 | Formula: C22H19Cl2N3O2
  • H donors: 0 H acceptors: 1 LogP: 5.4 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(=O)N1N=C(OC1c1c(Cl)cccc1Cl)c1ccc(cc1)n1c(C)ccc1C
  • InChi: 1S/C22H19Cl2N3O2/c1-13-7-8-14(2)26(13)17-11-9-16(10-12-17)21-25-27(15(3)28)22(29-21)20-18(23)5-4-6-19(20)24/h4-12,22H,1-3H3
  • InChiKey: RUABXKFVAWUZBN-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Protein kinase domain containing protein 0.0129 0.0026 0.0026
Entamoeba histolytica protein kinase, putative 0.0243 0.0389 0.1512
Brugia malayi Calcium binding EGF domain containing protein 0.0327 0.066 0.066
Echinococcus multilocularis slit 2 protein 0.0371 0.0801 0.0801
Echinococcus granulosus raf serine:threonine protein kinase 0.0147 0.0083 0.0083
Echinococcus granulosus calcium dependent protein kinase 0.0135 0.0043 0.0043
Schistosoma mansoni tyrosine kinase 0.0396 0.0882 0.0882
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.1122 0.3211 0.3211
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.02 0.0253 0.0253
Toxoplasma gondii AGC kinase 0.0224 0.033 0.0304
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0298 0.0566 0.0541
Brugia malayi Protein kinase domain containing protein 0.0303 0.0582 0.0582
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0151 0.0096 0.0096
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.1122 0.3211 0.3211
Brugia malayi hypothetical protein 0.0604 0.1549 0.1549
Schistosoma mansoni serine/threonine protein kinase 0.0402 0.09 0.09
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0274 0.049 0.1472
Onchocerca volvulus 0.0604 0.1549 0.6748
Schistosoma mansoni tyrosine kinase 0.0477 0.1142 0.1142
Brugia malayi Immunoglobulin I-set domain containing protein 0.0615 0.1584 0.1584
Trichomonas vaginalis AGC family protein kinase 0.0224 0.033 0.0971
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0131 0.003 0.0039
Echinococcus granulosus leucine rich repeat containing protein 4 0.0151 0.0096 0.0096
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0168 0.015 0.0123
Brugia malayi Tyrosine-protein kinase abl-1 0.0186 0.0206 0.0206
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.035 0.0734 0.0734
Onchocerca volvulus 0.0151 0.0096 0.036
Echinococcus granulosus dual specificity 0.0276 0.0496 0.0496
Schistosoma mansoni protein kinase 0.0128 0.0021 0.0021
Echinococcus granulosus cyclin dependent kinase 9 0.0159 0.0121 0.0121
Brugia malayi SH2 domain containing protein 0.0129 0.0026 0.0026
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0326 0.0655 0.0655
Brugia malayi Protein kinase domain containing protein 0.0243 0.0389 0.0389
Brugia malayi p70 ribosomal S6 kinase beta 0.0565 0.1422 0.1422
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0565 0.1422 0.1422
Trichomonas vaginalis CAMK family protein kinase 0.0155 0.0109 0.0276
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0199 0.0248 0.0123
Echinococcus multilocularis glutamate synthase 0.0298 0.0566 0.0566
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0305 0.0589 0.0563
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0255 0.043 0.0404
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0486 0.117 0.117
Echinococcus granulosus cyclin 0.0875 0.2418 0.2418
Loa Loa (eye worm) hypothetical protein 0.0332 0.0676 0.0676
Echinococcus granulosus cGMP dependent protein kinase 1 0.0167 0.0145 0.0145
Echinococcus multilocularis peroxidasin 0.0333 0.0678 0.0678
Brugia malayi Immunoglobulin I-set domain containing protein 0.0332 0.0676 0.0676
Trichomonas vaginalis AGC family protein kinase 0.0162 0.013 0.0342
Onchocerca volvulus Peroxidasin homolog 0.0151 0.0096 0.036
Echinococcus granulosus netrin receptor unc 5 0.0238 0.0375 0.0375
Echinococcus granulosus insulin receptor 0.0594 0.1515 0.1515
Echinococcus multilocularis protein tyrosine kinase 0.0567 0.1431 0.1431
Echinococcus granulosus growth factor receptor bound protein 2 0.0123 0.0006 0.0006
Echinococcus granulosus STE20 serine:threonine protein kinase 0.0981 0.2757 0.2757
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0199 0.0248 0.0248
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0359 0.0764 0.0764
Echinococcus granulosus tyrosine protein kinase Src42A 0.0302 0.058 0.058
Trichomonas vaginalis CAMK family protein kinase 0.0155 0.0109 0.0276
Onchocerca volvulus 0.0604 0.1549 0.6748
Loa Loa (eye worm) disorganized muscle protein 1 0.0151 0.0096 0.0096
Echinococcus granulosus protein kinase c iota type 0.0567 0.1429 0.1429
Trypanosoma cruzi casein kinase II, putative 0.0199 0.0248 0.0222
Schistosoma mansoni titin 0.0151 0.0096 0.0096
Brugia malayi serine/threonine protein kinase 6 0.0233 0.0358 0.0358
Echinococcus multilocularis leucine rich repeats and immunoglobulin 0.0152 0.0098 0.0098
Brugia malayi Variant SH3 domain containing protein 0.0148 0.0086 0.0086
Echinococcus multilocularis death associated protein kinase 1 0.0876 0.2422 0.2422
Brugia malayi probable protein kinase 0.0526 0.1297 0.1297
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0166 0.0144 0.0117
Echinococcus granulosus neuroglian 0.035 0.0734 0.0734
Onchocerca volvulus 0.0604 0.1549 0.6748
Trichomonas vaginalis CK1 family protein kinase 0.0216 0.0303 0.0884
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.089 0.2465 0.2465
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.1122 0.3211 0.3211
Brugia malayi Prion-like- 0.0151 0.0096 0.0096
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0148 0.0086 0.0086
Schistosoma mansoni serine/threonine protein kinase 0.0305 0.0589 0.0589
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0861 0.2372 0.2372
Trypanosoma brucei cdc2-related kinase 1 0.0236 0.0367 0.0341
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0298 0.0566 0.0566
Loa Loa (eye worm) hypothetical protein 0.0151 0.0096 0.0096
Plasmodium falciparum serine/threonine protein kinase KIN 0.0155 0.0109 0.0081
Loa Loa (eye worm) hypothetical protein 0.0367 0.0787 0.0787
Echinococcus multilocularis hemicentin 1 0.0332 0.0676 0.0676
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.1122 0.3211 0.3211
Loa Loa (eye worm) immunoglobulin domain-containing protein 0.0181 0.0191 0.0191
Trypanosoma cruzi aurora B kinase, putative 0.0233 0.0358 0.0332
Toxoplasma gondii AGC kinase 0.0224 0.033 0.0304
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0305 0.0589 0.0563
Schistosoma mansoni netrin receptor unc5 0.0238 0.0375 0.0375
Loa Loa (eye worm) TK protein kinase 0.0303 0.0582 0.0582
Echinococcus multilocularis protein jagged 2 0.0327 0.066 0.066
Echinococcus multilocularis rho associated protein kinase 0.0645 0.168 0.168
Loa Loa (eye worm) hypothetical protein 0.0366 0.0786 0.0786
Onchocerca volvulus 0.0283 0.0519 0.2221
Onchocerca volvulus 0.0645 0.168 0.7322
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0319 0.0635 0.0635
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0316 0.0624 0.0598
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0147 0.0081 0.0081
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0168 0.015 0.0123
Schistosoma mansoni slit 0.0328 0.0662 0.0662
Trichomonas vaginalis AGC family protein kinase 0.0233 0.0358 0.1059
Schistosoma mansoni protein kinase 0.0438 0.1017 0.1017
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0224 0.033 0.033
Loa Loa (eye worm) hypothetical protein 0.0332 0.0676 0.0676
Onchocerca volvulus 0.0327 0.066 0.2841
Loa Loa (eye worm) AGC/PKG protein kinase 0.0167 0.0145 0.0145
Schistosoma mansoni serine/threonine protein kinase 0.0483 0.1162 0.1162
Echinococcus granulosus tyrosine protein kinase Src64B 0.0302 0.058 0.058
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0699 0.1854 0.1854
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0233 0.0358 0.1386
Trichomonas vaginalis CAMK family protein kinase 0.0155 0.0109 0.0276
Schistosoma mansoni ste20-related kinase 0.0407 0.0916 0.0916
Echinococcus multilocularis dual specificity 0.0276 0.0496 0.0496
Plasmodium falciparum casein kinase 2, alpha subunit 0.0199 0.0248 0.0222
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0326 0.0655 0.0655
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0316 0.0624 0.0598
Onchocerca volvulus 0.0327 0.066 0.2841
Echinococcus multilocularis 0.019 0.0219 0.0219
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0359 0.0764 0.0764
Echinococcus granulosus serine:threonine protein kinase N2 0.0576 0.146 0.146
Brugia malayi EGF-like domain containing protein 0.0327 0.066 0.066
Loa Loa (eye worm) hypothetical protein 0.0327 0.066 0.066
Schistosoma mansoni peroxidasin 0.0181 0.0192 0.0192
Onchocerca volvulus 0.0327 0.066 0.2841
Trichomonas vaginalis AGC family protein kinase 0.0336 0.0688 0.2092
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0302 0.058 0.058
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0251 0.0416 0.0416
Plasmodium vivax calcium-dependent protein kinase, putative 0.02 0.0253 0.0128
Echinococcus multilocularis mitogen activated protein kinase 14 0.0316 0.0624 0.0624
Brugia malayi Immunoglobulin I-set domain containing protein 0.0169 0.0154 0.0154
Loa Loa (eye worm) hypothetical protein 0.0931 0.2599 0.2599
Trichomonas vaginalis STE family protein kinase 0.0168 0.015 0.0405
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.035 0.0734 0.0734
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0222 0.0322 0.0295
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0251 0.0416 0.0416
Plasmodium falciparum glutathione reductase 0.1122 0.3211 0.3192
Brugia malayi hypothetical protein 0.0615 0.1584 0.1584
Loa Loa (eye worm) hypothetical protein 0.0151 0.0096 0.0096
Echinococcus multilocularis myosin iiia 0.0168 0.015 0.015
Trichomonas vaginalis mercuric reductase, putative 0.1122 0.3211 1
Trichomonas vaginalis apoptosis inducing factor, putative 0.0298 0.0566 0.1711
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.02 0.0253 0.0226
Onchocerca volvulus Serine\/threonine kinase homolog 0.0326 0.0655 0.2818
Loa Loa (eye worm) hypothetical protein 0.0381 0.0834 0.0834
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0166 0.0144 0.0117
Trichomonas vaginalis CAMK family protein kinase 0.0155 0.0109 0.0276
Echinococcus multilocularis cyclin dependent kinase 1 0.0236 0.0367 0.0367
Echinococcus multilocularis tyrosine kinase 0.0129 0.0026 0.0026
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0224 0.033 0.0206
Echinococcus granulosus titin 0.0151 0.0096 0.0096
Echinococcus granulosus epidermal growth factor receptor 0.0477 0.1142 0.1142
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0287 0.0532 0.0532
Giardia lamblia High cysteine protein 0.0327 0.066 0.1695
Trichomonas vaginalis AGC family protein kinase 0.0233 0.0358 0.1059
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.035 0.0734 0.0734
Toxoplasma gondii EGF family domain-containing protein 0.0327 0.066 0.0635
Echinococcus multilocularis serine:threonine protein kinase N2 0.0257 0.0436 0.0436
Trypanosoma cruzi NADH dehydrogenase, putative 0.0298 0.0566 0.0541
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0298 0.0566 0.0445
Brugia malayi Protein kinase domain containing protein 0.034 0.0701 0.0701
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0298 0.0566 0.1711
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0302 0.058 0.058
Schistosoma mansoni myosin-binding protein-related 0.0169 0.0154 0.0154
Schistosoma mansoni nephrin 0.0766 0.2069 0.2069
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0298 0.0566 0.2239
Trypanosoma brucei cdc2-related kinase 3 0.0236 0.0367 0.0341
Giardia lamblia Kinase, CMGC MAPK 0.0166 0.0144 0.0013
Echinococcus granulosus casein kinase I delta 0.0216 0.0303 0.0303
Schistosoma mansoni tyrosine kinase 0.0413 0.0936 0.0936
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0181 0.0191 0.0191
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0148 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0214 0.0296 0.0296
Echinococcus granulosus serine/threonine protein kinase 0.0326 0.0656 0.0656
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0298 0.0566 0.0541
Entamoeba histolytica PH domain containing protein kinase, putative 0.0326 0.0656 0.2607
Plasmodium vivax thioredoxin reductase, putative 0.3238 1 1
Echinococcus multilocularis cyclin dependent kinase 19 0.1173 0.3373 0.3373
Echinococcus granulosus tyrosine protein kinase Lyn 0.0368 0.079 0.079
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0431 0.0994 0.0994
Brugia malayi Immunoglobulin I-set domain containing protein 0.035 0.0734 0.0734
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0298 0.0566 0.0541
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0166 0.0144 0.0144
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0255 0.043 0.043
Schistosoma mansoni nephrin related 0.0181 0.0191 0.0191
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.035 0.0734 0.0734
Schistosoma mansoni serine/threonine protein kinase 0.0251 0.0416 0.0416
Leishmania major hypothetical protein, conserved 0.0298 0.0566 0.0541
Echinococcus granulosus oligomeric golgi complex subunit 3 0.0875 0.2418 0.2418
Loa Loa (eye worm) hypothetical protein 0.0915 0.2546 0.2546
Loa Loa (eye worm) hypothetical protein 0.0239 0.0379 0.0379
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0298 0.0566 0.2239
Echinococcus granulosus Vam6:Vps39 protein 0.0222 0.0322 0.0322
Entamoeba histolytica PH domain containing protein kinase, putative 0.0239 0.0379 0.1469
Leishmania major casein kinase, putative 0.0216 0.0303 0.0276
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0251 0.0416 0.0416
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.035 0.0734 0.0734
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0332 0.0676 0.0676
Schistosoma mansoni hypothetical protein 0.0327 0.066 0.066
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0255 0.043 0.0404
Plasmodium falciparum casein kinase 1 0.0216 0.0303 0.0276
Loa Loa (eye worm) AGC/AKT protein kinase 0.058 0.147 0.147
Loa Loa (eye worm) gastrulation defective protein 1 0.1107 0.3163 0.3163
Onchocerca volvulus Putative cubilin 0.0327 0.066 0.2841
Schistosoma mansoni protein kinase 0.0216 0.0303 0.0303
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0486 0.117 0.117
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0316 0.0624 0.0598
Plasmodium falciparum serine/threonine protein kinase 0.0165 0.014 0.0113
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0302 0.058 0.058
Echinococcus granulosus C type lectin domian containing protein 0.0604 0.1549 0.1549
Loa Loa (eye worm) TK/FER protein kinase 0.0431 0.0994 0.0994
Brugia malayi Immunoglobulin I-set domain containing protein 0.0235 0.0364 0.0364
Loa Loa (eye worm) protein kinase domain-containing protein 0.0423 0.0968 0.0968
Schistosoma mansoni cell adhesion molecule 0.035 0.0734 0.0734
Brugia malayi Prion-like- 0.0151 0.0096 0.0096
Plasmodium falciparum thioredoxin reductase 0.3238 1 1
Echinococcus granulosus fibroblast growth factor receptor 4 0.0359 0.0764 0.0764
Giardia lamblia Kinase, AGC PKA 0.0224 0.033 0.062
Loa Loa (eye worm) hypothetical protein 0.0327 0.066 0.066
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0298 0.0566 0.0541
Toxoplasma gondii selenide, water dikinase 0.0298 0.0566 0.0541
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0441 0.1025 0.1025
Echinococcus granulosus tyrosine protein kinase Blk 0.0246 0.04 0.04
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.1122 0.3211 0.2803
Echinococcus granulosus rho-associated protein kinase 1 0.0645 0.168 0.168
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0332 0.0676 0.0676
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.02 0.0253 0.0253
Schistosoma mansoni hypothetical protein 0.0222 0.0322 0.0322
Schistosoma mansoni basigin related 0.0181 0.0191 0.0191
Trichomonas vaginalis CMGC family protein kinase 0.0178 0.0182 0.0507
Trichomonas vaginalis CMGC family protein kinase 0.0276 0.0496 0.1489
Schistosoma mansoni tyrosine kinase 0.0302 0.058 0.058
Echinococcus granulosus hypothetical protein 0.0239 0.0379 0.0379
Brugia malayi Prion-like- 0.0151 0.0096 0.0096
Loa Loa (eye worm) hypothetical protein 0.0224 0.033 0.033
Echinococcus multilocularis casein kinase i 0.0216 0.0303 0.0303
Schistosoma mansoni glutamate synthase 0.0298 0.0566 0.0566
Echinococcus granulosus cyclin dependent kinase 9 0.0175 0.0174 0.0174
Echinococcus granulosus epidermal growth factor receptor 0.0684 0.1806 0.1806
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0228 0.0344 0.0344
Entamoeba histolytica protein kinase, putative 0.0255 0.043 0.168
Entamoeba histolytica cell division protein kinase 2, putative 0.0236 0.0367 0.1422
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0162 0.013 0.013
Leishmania major hypothetical protein, conserved 0.0298 0.0566 0.0541
Loa Loa (eye worm) hypothetical protein 0.0327 0.066 0.066
Leishmania major protein kinase A catalytic subunit 0.0224 0.033 0.0304
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0536 0.1331 0.1331
Schistosoma mansoni hypothetical protein 0.0181 0.0191 0.0191
Schistosoma mansoni hemicentin 0.0169 0.0154 0.0154
Echinococcus multilocularis ephrin type A receptor 4 A 0.0191 0.0224 0.0224
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0165 0.014 0.0113
Brugia malayi Protein kinase domain containing protein 0.0123 0.0005 0.0005
Brugia malayi Cadherin domain containing protein 0.0327 0.0661 0.0661
Giardia lamblia Kinase, CDC7 0.0178 0.0182 0.0138
Brugia malayi cell division control protein 2 homolog 0.0236 0.0367 0.0367
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0327 0.066 0.066
Echinococcus granulosus casein kinase I alpha 0.0216 0.0303 0.0303
Echinococcus multilocularis protein kinase shaggy 0.0255 0.043 0.043
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0305 0.0589 0.0563
Trichomonas vaginalis AGC family protein kinase 0.058 0.147 0.4544
Onchocerca volvulus 0.0129 0.0026 0.0052
Echinococcus granulosus 3'partial|cell adhesion molecule:down regulated by 0.0181 0.0191 0.0191
Echinococcus granulosus Immunoglobulin subtype 0.0181 0.0191 0.0191
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0477 0.1142 0.1142
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0222 0.0322 0.0322
Loa Loa (eye worm) hypothetical protein 0.0162 0.0129 0.0129
Echinococcus granulosus ephrin type A receptor 4 A 0.0191 0.0224 0.0224
Schistosoma mansoni serine/threonine protein kinase 0.0235 0.0364 0.0364
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.02 0.0253 0.0253
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0236 0.0367 0.0341
Brugia malayi Myb-like DNA-binding domain containing protein 0.0151 0.0096 0.0096
Echinococcus multilocularis serine:threonine protein kinase 0.0226 0.0337 0.0337
Schistosoma mansoni serine/threonine protein kinase 0.0486 0.117 0.117
Loa Loa (eye worm) hypothetical protein 0.046 0.1086 0.1086
Entamoeba histolytica protein kinase domain containing protein 0.0199 0.0248 0.0934
Schistosoma mansoni hypothetical protein 0.0181 0.0191 0.0191
Echinococcus granulosus defective proboscis extension response 0.0597 0.1526 0.1526
Brugia malayi Immunoglobulin I-set domain containing protein 0.0151 0.0096 0.0096
Brugia malayi glutamate synthase 0.0298 0.0566 0.0566
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0165 0.014 0.014
Entamoeba histolytica protein kinase, putative 0.0565 0.1422 0.575
Loa Loa (eye worm) hypothetical protein 0.0327 0.066 0.066
Echinococcus granulosus fibropellin Ia 0.0327 0.066 0.066
Mycobacterium tuberculosis Probable oxidoreductase 0.1122 0.3211 0.2803
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0224 0.033 0.033
Brugia malayi Protein kinase domain containing protein 0.058 0.147 0.147
Echinococcus granulosus tyrosine protein kinase Fyn 0.0302 0.058 0.058
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0728 0.1945 0.1945
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0224 0.033 0.0304
Echinococcus multilocularis netrin receptor unc 5 0.0238 0.0375 0.0375
Schistosoma mansoni notch 0.0327 0.066 0.066
Entamoeba histolytica protein kinase, putative 0.0131 0.003 0.0039
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0483 0.1162 0.1162
Onchocerca volvulus 0.0151 0.0096 0.036
Echinococcus multilocularis Immunoglobulin 0.0181 0.0191 0.0191
Echinococcus granulosus serine threonine protein kinase nrc 0.0311 0.0608 0.0608
Leishmania major protein kinase, putative 0.0233 0.0358 0.0332
Echinococcus granulosus serine:threonine protein kinase 0.0226 0.0337 0.0337
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0302 0.058 0.058
Schistosoma mansoni serine/threonine protein kinase 0.0699 0.1854 0.1854
Entamoeba histolytica casein kinase 1, putative 0.0216 0.0303 0.1157
Trichomonas vaginalis CAMK family protein kinase 0.0536 0.1331 0.4107
Toxoplasma gondii rhoptry neck protein RON1 0.0604 0.1549 0.1526
Brugia malayi Sushi domain 0.0604 0.1549 0.1549
Echinococcus multilocularis dual specificity 0.0276 0.0496 0.0496
Echinococcus granulosus roundabout 2 0.035 0.0734 0.0734
Schistosoma mansoni serine/threonine protein kinase 0.0183 0.0197 0.0197
Loa Loa (eye worm) TK/FER protein kinase 0.0129 0.0026 0.0026
Loa Loa (eye worm) AGC/PKA protein kinase 0.0224 0.033 0.033
Schistosoma mansoni serine/threonine protein kinase 0.0506 0.1234 0.1234
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.1122 0.3211 0.3192
Loa Loa (eye worm) hypothetical protein 0.0604 0.1549 0.1549
Schistosoma mansoni hypothetical protein 0.0181 0.0191 0.0191
Trichomonas vaginalis glutathione reductase, putative 0.1122 0.3211 1
Loa Loa (eye worm) hypothetical protein 0.0177 0.0179 0.0179
Loa Loa (eye worm) hypothetical protein 0.0151 0.0096 0.0096
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0597 0.1526 0.1526
Loa Loa (eye worm) TK/FER protein kinase 0.0129 0.0026 0.0026
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1122 0.3211 0.3192
Schistosoma mansoni c4b-binding protein beta chain 0.0604 0.1549 0.1549
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0597 0.1526 0.1526
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0524 0.1293 0.1293
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0181 0.0191 0.0191
Giardia lamblia Kinase, PLK 0.0536 0.1331 0.3878
Plasmodium falciparum ferrodoxin reductase-like protein 0.0298 0.0566 0.0541
Echinococcus multilocularis casein kinase I delta 0.0216 0.0303 0.0303
Loa Loa (eye worm) TK/FER protein kinase 0.0129 0.0026 0.0026
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0167 0.0145 0.0145
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.1122 0.3211 0.3192
Loa Loa (eye worm) TK/EPH protein kinase 0.0226 0.0336 0.0336
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0298 0.0566 0.0541
Schistosoma mansoni atypical protein kinase C 0.0579 0.1468 0.1468
Entamoeba histolytica protein kinase, putative 0.0203 0.0261 0.0986
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0195 0.0237 0.0237
Entamoeba histolytica cyclin C, putative 0.0887 0.2458 1
Brugia malayi Protein kinase domain containing protein 0.0129 0.0026 0.0026
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0824 0.2255 0.2255
Echinococcus granulosus tyrosine kinase 0.0129 0.0026 0.0026
Echinococcus granulosus roundabout 2 0.0947 0.2649 0.2649
Loa Loa (eye worm) hypothetical protein 0.0327 0.066 0.066
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0778 0.2106 0.2106
Brugia malayi ephrin receptor 1 precursor 0.0124 0.0009 0.0009
Schistosoma mansoni serine/threonine protein kinase 0.02 0.0253 0.0253
Trichomonas vaginalis CMGC family protein kinase 0.0236 0.0367 0.1086
Brugia malayi Leucine Rich Repeat family protein 0.0152 0.0098 0.0098
Echinococcus granulosus mitogen activated protein kinase 11 0.0316 0.0624 0.0624
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0155 0.0109 0.0109
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0166 0.0144 0.0117
Entamoeba histolytica cell division protein kinase 2, putative 0.0252 0.042 0.1638
Schistosoma mansoni tyrosine kinase 0.0126 0.0017 0.0017
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0298 0.0566 0.0566
Brugia malayi cyclin-dependent kinase 9 0.0159 0.0121 0.0121
Trichomonas vaginalis STE family protein kinase 0.0171 0.0159 0.0432
Loa Loa (eye worm) TK protein kinase 0.0246 0.04 0.04
Echinococcus multilocularis neuroglian 0.0748 0.2012 0.2012
Brugia malayi Immunoglobulin I-set domain containing protein 0.0181 0.0191 0.0191
Schistosoma mansoni cell polarity protein 0.0327 0.066 0.066
Echinococcus granulosus titin 0.0151 0.0096 0.0096
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0298 0.0566 0.0541
Echinococcus granulosus protein kinase 0.0304 0.0586 0.0586
Trichomonas vaginalis CAMK family protein kinase 0.0536 0.1331 0.4107
Brugia malayi Immunoglobulin I-set domain containing protein 0.0199 0.0248 0.0248
Schistosoma mansoni serine/threonine protein kinase 0.0576 0.146 0.146
Schistosoma mansoni serine/threonine protein kinase 0.0159 0.0121 0.0121
Entamoeba histolytica protein kinase domain containing protein 0.0255 0.043 0.168
Schistosoma mansoni septate junction protein 0.0327 0.066 0.066
Trichomonas vaginalis AGC family protein kinase 0.0162 0.013 0.0342
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0168 0.015 0.0531
Brugia malayi hypothetical protein 0.0604 0.1549 0.1549
Echinococcus multilocularis hypothetical protein 0.0202 0.0259 0.0259
Schistosoma mansoni hypothetical protein 0.0327 0.066 0.066
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0251 0.0416 0.0416
Echinococcus multilocularis mitogen activated protein kinase 11 0.0316 0.0624 0.0624
Loa Loa (eye worm) hypothetical protein 0.02 0.0253 0.0253
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0429 0.0986 0.0986
Brugia malayi Protein kinase domain containing protein 0.0384 0.0844 0.0844
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0429 0.0986 0.0986
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0298 0.0566 0.0566
Brugia malayi Immunoglobulin I-set domain containing protein 0.0169 0.0154 0.0154
Echinococcus multilocularis serine:threonine protein kinase N2 0.0319 0.0635 0.0635
Echinococcus multilocularis tyrosine protein kinase shark 0.0342 0.0707 0.0707
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0169 0.0154 0.0154
Echinococcus multilocularis lachesin 0.0332 0.0676 0.0676
Brugia malayi EGF-like domain containing protein 0.0327 0.066 0.066
Brugia malayi Protein kinase domain containing protein 0.0699 0.1854 0.1854
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0302 0.058 0.058
Echinococcus multilocularis neurogenic locus protein delta 0.0327 0.066 0.066
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0224 0.033 0.033
Onchocerca volvulus 0.0129 0.0026 0.0052
Loa Loa (eye worm) AUR protein kinase 0.0233 0.0358 0.0358
Brugia malayi hypothetical protein 0.0181 0.0191 0.0191
Echinococcus multilocularis casein kinase ii subunit alpha 0.0199 0.0248 0.0248
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0243 0.0389 0.0363
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0233 0.0358 0.0358
Echinococcus granulosus neural cadherin 0.0327 0.0661 0.0661
Schistosoma mansoni tyrosine kinase 0.0477 0.1142 0.1142
Schistosoma mansoni kinase 0.0159 0.0121 0.0121
Brugia malayi EGF-like domain containing protein 0.0327 0.066 0.066
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0398 0.0889 0.0889
Echinococcus granulosus Down syndrome cell adhesion molecule 0.0199 0.0248 0.0248
Echinococcus granulosus nervana 2 0.0245 0.0398 0.0398
Loa Loa (eye worm) hypothetical protein 0.0283 0.0519 0.0519
Echinococcus multilocularis tyrosine protein kinase 0.0303 0.0582 0.0582
Schistosoma mansoni serine/threonine protein kinase 0.0224 0.033 0.033
Schistosoma mansoni hypothetical protein 0.0151 0.0096 0.0096
Onchocerca volvulus 0.0152 0.0098 0.0368
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0224 0.033 0.033
Trichomonas vaginalis CMGC family protein kinase 0.0199 0.0248 0.0714
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.1122 0.3211 1
Giardia lamblia Kinase, AGC AKT 0.0232 0.0356 0.0704
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0255 0.043 0.043
Brugia malayi Protein kinase domain containing protein 0.0162 0.013 0.013
Schistosoma mansoni protein kinase 0.0861 0.2372 0.2372
Toxoplasma gondii rhoptry neck protein RON9 0.0604 0.1549 0.1526
Loa Loa (eye worm) hypothetical protein 0.0332 0.0676 0.0676
Schistosoma mansoni serine/threonine protein kinase 0.0946 0.2646 0.2646
Echinococcus granulosus protein kinase c epsilon type 0.0405 0.0909 0.0909
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0432 0.0996 0.0996
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0224 0.033 0.033
Brugia malayi Protein kinase domain containing protein 0.0278 0.0503 0.0503
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0298 0.0566 0.0541
Entamoeba histolytica casein kinase, putative 0.0199 0.0248 0.0934
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0298 0.0566 0.0566
Plasmodium falciparum cGMP-dependent protein kinase 0.0167 0.0145 0.0118
Brugia malayi Wrapper/rega-1/klingon homolog protein 1 0.0151 0.0096 0.0096
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0536 0.1331 0.1307
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0169 0.0154 0.0154
Giardia lamblia Kinase, NEK 0.027 0.0478 0.1099
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0243 0.0389 0.0363
Loa Loa (eye worm) TK/FER protein kinase 0.0129 0.0026 0.0026
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0311 0.0608 0.0487
Brugia malayi EGF-like domain containing protein 0.0327 0.066 0.066
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.034 0.0701 0.0701
Brugia malayi Immunoglobulin I-set domain containing protein 0.0151 0.0096 0.0096
Brugia malayi Thioredoxin reductase 0.3238 1 1
Loa Loa (eye worm) hypothetical protein 0.0327 0.066 0.066
Schistosoma mansoni cell adhesion molecule 0.0181 0.0191 0.0191
Schistosoma mansoni hypothetical protein 0.0327 0.066 0.066
Echinococcus multilocularis leucine rich repeat containing protein 4 0.0181 0.0191 0.0191
Brugia malayi Protein kinase domain 0.0171 0.0159 0.0159
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0148 0.0086 0.0086
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.1122 0.3211 0.3192
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0245 0.0398 0.0398
Schistosoma mansoni cell adhesion molecule 0.035 0.0734 0.0734
Entamoeba histolytica protein kinase domain containing protein 0.0233 0.0358 0.1386
Trypanosoma cruzi casein kinase, putative 0.0216 0.0303 0.0276
Trichomonas vaginalis CAMK family protein kinase 0.0536 0.1331 0.4107
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0466 0.1106 0.1106
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0184 0.02 0.02
Echinococcus multilocularis N chimaerin 0.0148 0.0086 0.0086
Echinococcus multilocularis protein jagged 1 0.0327 0.066 0.066
Schistosoma mansoni cell adhesion molecule 0.0169 0.0154 0.0154
Loa Loa (eye worm) hypothetical protein 0.0615 0.1584 0.1584
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0236 0.0367 0.0367
Leishmania major acetoin dehydrogenase e3 component-like protein 0.1122 0.3211 0.3192
Brugia malayi Immunoglobulin I-set domain containing protein 0.0332 0.0676 0.0676
Schistosoma mansoni septate junction protein 0.0332 0.0676 0.0676
Echinococcus multilocularis cyclin dependent kinase 9 0.0159 0.0121 0.0121
Loa Loa (eye worm) pregnancy-associated plasma protein-E 0.0604 0.1549 0.1549
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0155 0.0109 0.0081
Trichomonas vaginalis CMGC family protein kinase 0.0178 0.0182 0.0507
Brugia malayi Immunoglobulin I-set domain containing protein 0.0151 0.0096 0.0096
Brugia malayi Fes/CIP4 homology domain containing protein 0.0203 0.0261 0.0261
Echinococcus granulosus Immunoglobulin 0.0181 0.0191 0.0191
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0298 0.0566 0.1711
Schistosoma mansoni serine/threonine protein kinase 0.0398 0.0889 0.0889
Trypanosoma cruzi casein kinase, putative 0.0216 0.0303 0.0276
Brugia malayi Temporarily assigned gene name protein 59 0.0256 0.0431 0.0431
Brugia malayi phosphoinositide-dependent protein kinase I 0.0162 0.013 0.013
Brugia malayi Calcium binding EGF domain containing protein 0.0327 0.066 0.066
Entamoeba histolytica protein kinase, putative 0.058 0.147 0.5948
Schistosoma mansoni protein kinase 0.0438 0.1017 0.1017
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.02 0.0253 0.0226
Schistosoma mansoni serine/threonine protein kinase 0.0268 0.0469 0.0469
Brugia malayi Protein kinase domain containing protein 0.089 0.2465 0.2465
Brugia malayi Muscle positioning protein 4 0.0327 0.066 0.066
Echinococcus multilocularis serine:threonine protein kinase N2 0.0576 0.146 0.146
Brugia malayi Protein kinase domain containing protein 0.0594 0.1515 0.1515
Schistosoma mansoni nephrin 0.035 0.0734 0.0734
Echinococcus multilocularis nervana 2 0.0245 0.0398 0.0398
Echinococcus granulosus Immunoglobulin 0.0181 0.0191 0.0191
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0302 0.058 0.058
Echinococcus multilocularis 0.0151 0.0096 0.0096
Trichomonas vaginalis CAMK family protein kinase 0.0155 0.0109 0.0276
Plasmodium vivax casein kinase 1, putative 0.0216 0.0303 0.0178
Loa Loa (eye worm) hypothetical protein 0.0169 0.0154 0.0154
Entamoeba histolytica protein kinase, putative 0.058 0.147 0.5948
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0168 0.015 0.0531
Schistosoma mansoni serine/threonine protein kinase 0.0441 0.1025 0.1025
Echinococcus multilocularis Glutaredoxin protein 5 0.0245 0.0398 0.0398
Schistosoma mansoni serine/threonine protein kinase 0.0167 0.0145 0.0145
Entamoeba histolytica hypothetical protein 0.0378 0.0823 0.3292
Onchocerca volvulus 0.0178 0.0182 0.074
Loa Loa (eye worm) hypothetical protein 0.0222 0.0322 0.0322
Onchocerca volvulus 0.0579 0.147 0.6398
Echinococcus multilocularis casein kinase I delta 0.0216 0.0303 0.0303
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.02 0.0253 0.0253
Entamoeba histolytica protein kinase , putative 0.0233 0.0358 0.1386
Schistosoma mansoni tyrosine kinase 0.0342 0.0707 0.0707
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0151 0.0096 0.0096
Loa Loa (eye worm) hypothetical protein 0.0275 0.0494 0.0494
Brugia malayi Protein kinase domain containing protein 0.0178 0.0182 0.0182
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0166 0.0144 0.0117
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0276 0.0496 0.047
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0429 0.0986 0.0986
Echinococcus granulosus thioredoxin glutathione reductase 0.3238 1 1
Brugia malayi hypothetical protein 0.0604 0.1549 0.1549
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0536 0.1331 0.1331
Trichomonas vaginalis CAMK family protein kinase 0.0155 0.0109 0.0276
Brugia malayi Protein kinase domain containing protein 0.0236 0.0367 0.0367
Loa Loa (eye worm) hypothetical protein 0.0327 0.066 0.066
Schistosoma mansoni serine/threonine protein kinase 0.0645 0.168 0.168
Loa Loa (eye worm) hypothetical protein 0.0202 0.0259 0.0259
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0699 0.1854 0.1854
Leishmania major dihydrolipoamide dehydrogenase, putative 0.1122 0.3211 0.3192
Loa Loa (eye worm) hypothetical protein 0.0327 0.066 0.066
Loa Loa (eye worm) hypothetical protein 0.0151 0.0096 0.0096
Plasmodium falciparum thioredoxin reductase 0.1122 0.3211 0.3192
Loa Loa (eye worm) TK/ROR protein kinase 0.0216 0.0302 0.0302
Onchocerca volvulus 0.0169 0.0154 0.0614
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0216 0.0302 0.0302
Schistosoma mansoni tyrosine kinase 0.0277 0.0498 0.0498
Echinococcus granulosus c4b binding protein beta chain 0.0604 0.1549 0.1549
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0782 0.2119 0.2119
Echinococcus granulosus mitogen activated protein kinase 3 0.0166 0.0144 0.0144
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0181 0.0191 0.0191
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0298 0.0566 0.0566
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0699 0.1854 0.809
Brugia malayi Hr1 repeat family protein 0.0576 0.146 0.146
Brugia malayi protein kinase C3,putative 0.0313 0.0615 0.0615
Schistosoma mansoni tyrosine kinase 0.0413 0.0936 0.0936
Schistosoma mansoni tyrosine kinase 0.0186 0.0206 0.0206
Trichomonas vaginalis CMGC family protein kinase 0.0276 0.0496 0.1489
Onchocerca volvulus 0.0216 0.0303 0.1268
Echinococcus multilocularis neuroglian 0.035 0.0734 0.0734
Entamoeba histolytica protein kinase 2, putative 0.0311 0.0608 0.2409
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0129 0.0026 0.0026
Loa Loa (eye worm) TK/EGFR protein kinase 0.0684 0.1806 0.1806
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0298 0.0566 0.0566
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.1122 0.3211 0.3124
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0597 0.1526 0.1526
Echinococcus granulosus nephrin 0.0169 0.0154 0.0154
Schistosoma mansoni serine/threonine protein kinase 0.0429 0.0986 0.0986
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.1122 0.3211 0.2803
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0298 0.0566 0.0541
Trichomonas vaginalis CAMK family protein kinase 0.0155 0.0109 0.0276
Echinococcus granulosus notch 0.0327 0.066 0.066
Schistosoma mansoni serine/threonine protein kinase 0.0319 0.0635 0.0635
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0305 0.0589 0.0589
Schistosoma mansoni serine/threonine protein kinase 0.0466 0.1106 0.1106
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.1442 0.4236 0.4236
Leishmania major protein kinase, putative 0.0168 0.015 0.0123
Entamoeba histolytica protein kinase, putative 0.0165 0.014 0.049
Loa Loa (eye worm) hypothetical protein 0.0778 0.2106 0.2106
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0224 0.033 0.033
Plasmodium vivax apical sushi protein, putative 0.0604 0.1549 0.1441
Brugia malayi serine/threonine kinase 12 0.0233 0.0358 0.0358
Entamoeba histolytica protein kinase, putative 0.0171 0.0159 0.0566
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0168 0.015 0.0123
Echinococcus granulosus tyrosine protein kinase otk 0.0332 0.0676 0.0676
Schistosoma mansoni titin 0.0151 0.0096 0.0096
Echinococcus granulosus NDR protein kinase 0.0319 0.0635 0.0635
Echinococcus multilocularis protein kinase c iota type 0.0567 0.1429 0.1429
Brugia malayi Prion-like- 0.0332 0.0676 0.0676
Echinococcus multilocularis nervana 2 0.0245 0.0398 0.0398
Onchocerca volvulus 0.0604 0.1549 0.6748
Loa Loa (eye worm) TK protein kinase 0.0181 0.0191 0.0191
Echinococcus multilocularis neural cadherin 0.0327 0.0661 0.0661
Brugia malayi Protein kinase domain containing protein 0.0629 0.1629 0.1629
Echinococcus granulosus cyclin dependent kinase 19 0.1173 0.3373 0.3373
Onchocerca volvulus Netrin receptor homolog 0.0209 0.028 0.1169
Brugia malayi Protein kinase domain containing protein 0.0326 0.0655 0.0655
Echinococcus multilocularis Down syndrome cell adhesion molecule 0.0199 0.0248 0.0248
Onchocerca volvulus 0.0327 0.066 0.2841
Echinococcus granulosus neurogenic locus notch protein 0.0327 0.066 0.066
Loa Loa (eye worm) hypothetical protein 0.0226 0.0337 0.0337
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0298 0.0566 0.0541
Brugia malayi serine/threonine-protein kinase plk-2 0.0536 0.1331 0.1331
Brugia malayi hypothetical protein 0.0222 0.0322 0.0322
Trichomonas vaginalis CAMK family protein kinase 0.0155 0.0109 0.0276
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0243 0.0389 0.0363
Schistosoma mansoni tyrosine kinase 0.0302 0.058 0.058
Loa Loa (eye worm) TK/INSR protein kinase 0.0594 0.1515 0.1515
Trypanosoma cruzi NADH dehydrogenase, putative 0.0298 0.0566 0.0541
Trypanosoma brucei trypanothione reductase 0.3238 1 1
Brugia malayi protein kinase C II. 0.0405 0.0909 0.0909
Schistosoma mansoni tyrosine kinase 0.0413 0.0936 0.0936
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0429 0.0986 0.0986
Toxoplasma gondii histone kinase SNF1, putative 0.0155 0.0109 0.0081
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0245 0.0398 0.0398
Brugia malayi casein kinase 1, delta 0.0216 0.0303 0.0303
Trichomonas vaginalis AGC family protein kinase 0.058 0.147 0.4544
Plasmodium falciparum calcium-dependent protein kinase 2 0.02 0.0253 0.0226
Loa Loa (eye worm) hypothetical protein 0.0597 0.1526 0.1526
Loa Loa (eye worm) hypothetical protein 0.0333 0.0678 0.0678
Brugia malayi Serine/threonine-protein kinase SULU 0.0441 0.1025 0.1025
Giardia lamblia Kinase, CMGC GSK 0.0255 0.043 0.0944
Brugia malayi RhoGAP domain containing protein 0.0148 0.0086 0.0086
Echinococcus granulosus dual specificity 0.0276 0.0496 0.0496
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0165 0.014 0.0113
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0224 0.033 0.0304
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0298 0.0566 0.0566
Schistosoma mansoni tyrosine kinase 0.0594 0.1515 0.1515
Onchocerca volvulus 0.0604 0.1549 0.6748
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0451 0.1057 0.1057
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0224 0.033 0.0304
Schistosoma mansoni tyrosine kinase 0.0186 0.0206 0.0206
Plasmodium falciparum protein serine/threonine kinase-1 0.0305 0.0589 0.0563
Schistosoma mansoni serine/threonine protein kinase 0.0782 0.2119 0.2119
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0178 0.0182 0.0182
Trypanosoma cruzi hypothetical protein, conserved 0.0298 0.0566 0.0541
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0166 0.0144 0.0117
Echinococcus granulosus basement membrane specific heparan sulfate 0.0181 0.0191 0.0191
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0728 0.1945 0.1945
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0405 0.0909 0.0909
Loa Loa (eye worm) CDC7 protein kinase 0.0178 0.0182 0.0182
Loa Loa (eye worm) AGC/PKA protein kinase 0.0224 0.033 0.033
Loa Loa (eye worm) LAD-2 short isoform 0.0181 0.0191 0.0191
Loa Loa (eye worm) hypothetical protein 0.0207 0.0275 0.0275
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0298 0.0566 0.2239
Trichomonas vaginalis CMGC family protein kinase 0.0276 0.0496 0.1489
Loa Loa (eye worm) SRC-1 0.0302 0.058 0.058
Plasmodium vivax glycogen synthase kinase 3, putative 0.0255 0.043 0.0307
Echinococcus multilocularis rac serine:threonine kinase 0.0326 0.0656 0.0656
Loa Loa (eye worm) hypothetical protein 0.0595 0.1518 0.1518
Echinococcus granulosus peroxidasin 0.0333 0.0678 0.0678
Schistosoma mansoni protein kinase 0.0861 0.2372 0.2372
Loa Loa (eye worm) hypothetical protein 0.0604 0.1549 0.1549
Brugia malayi Protein kinase domain containing protein 0.043 0.0992 0.0992
Schistosoma mansoni notch 0.0327 0.066 0.066
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.02 0.0253 0.0253
Loa Loa (eye worm) hypothetical protein 0.0275 0.0494 0.0494
Onchocerca volvulus 0.0604 0.1549 0.6748
Brugia malayi Immunoglobulin I-set domain containing protein 0.0151 0.0096 0.0096
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0298 0.0566 0.0566
Schistosoma mansoni serine/threonine protein kinase 0.1173 0.3373 0.3373
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0316 0.0624 0.0598
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0298 0.0566 0.1711
Giardia lamblia Kinase, STE STE20 0.0171 0.0159 0.006
Echinococcus multilocularis dual specificity 0.0243 0.0389 0.0389
Trichomonas vaginalis CK1 family protein kinase 0.0216 0.0303 0.0884
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0165 0.014 0.0113
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0232 0.0356 0.0356
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.1122 0.3211 1
Onchocerca volvulus 0.0129 0.0026 0.0052
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0224 0.033 0.0304
Brugia malayi Immunoglobulin I-set domain containing protein 0.0151 0.0096 0.0096
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.02 0.0253 0.0128
Plasmodium falciparum calcium-dependent protein kinase 5 0.02 0.0253 0.0226
Giardia lamblia Kinase, CMGC GSK 0.0255 0.043 0.0944
Schistosoma mansoni titin 0.0151 0.0096 0.0096
Entamoeba histolytica protein kinase, putative 0.0276 0.0496 0.1949
Trypanosoma cruzi cdc2-related kinase 3 0.0236 0.0367 0.0341
Entamoeba histolytica p21-activated kinase 0.0186 0.0207 0.0764
Schistosoma mansoni vam6/vps39 related 0.0222 0.0322 0.0322
Giardia lamblia Kinase, STE STE20 0.0168 0.015 0.0032
Echinococcus granulosus cGMP dependent protein kinase 0.0167 0.0145 0.0145
Schistosoma mansoni hypothetical protein 0.0298 0.0566 0.0566
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.02 0.0253 0.0226
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0699 0.1854 0.1854
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0319 0.0635 0.0635
Loa Loa (eye worm) hypothetical protein 0.0327 0.066 0.066
Trichomonas vaginalis STE family protein kinase 0.0171 0.0159 0.0432
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0287 0.0533 0.0533
Giardia lamblia Kinase, NEK 0.027 0.0478 0.1099
Schistosoma mansoni sulfide quinone reductase 0.0298 0.0566 0.0566
Brugia malayi Immunoglobulin I-set domain containing protein 0.0169 0.0154 0.0154
Schistosoma mansoni cell adhesion molecule 0.0332 0.0676 0.0676
Loa Loa (eye worm) AUR protein kinase 0.0233 0.0358 0.0358
Plasmodium vivax protein kinase Crk2 0.0236 0.0367 0.0244
Giardia lamblia Kinase, CMGC CDK 0.0236 0.0367 0.074
Loa Loa (eye worm) hypothetical protein 0.0151 0.0096 0.0096
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0226 0.0337 0.0337
Trypanosoma cruzi polo-like protein kinase, putative 0.0536 0.1331 0.1307
Echinococcus granulosus dual specificity 0.0243 0.0389 0.0389
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0159 0.012 0.012
Trichomonas vaginalis CMGC family protein kinase 0.0255 0.043 0.1283
Loa Loa (eye worm) hypothetical protein 0.0151 0.0096 0.0096
Schistosoma mansoni serine/threonine protein kinase 0.0536 0.1331 0.1331
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0171 0.0159 0.0159
Echinococcus granulosus aurora kinase A 0.0233 0.0358 0.0358
Trichomonas vaginalis CMGC family protein kinase 0.0199 0.0248 0.0714
Schistosoma mansoni notch 0.0327 0.066 0.066
Echinococcus granulosus protein kinase C gamma type 0.0401 0.0896 0.0896
Loa Loa (eye worm) thioredoxin reductase 0.3238 1 1
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0199 0.0248 0.0248
Brugia malayi C1-like domain containing protein 0.0432 0.0996 0.0996
Onchocerca volvulus 0.0604 0.1549 0.6748
Trichomonas vaginalis CMGC family protein kinase 0.0199 0.0248 0.0714
Brugia malayi Immunoglobulin I-set domain containing protein 0.1461 0.4299 0.4299
Schistosoma mansoni serine/threonine protein kinase 0.0276 0.0496 0.0496
Loa Loa (eye worm) hypothetical protein 0.0604 0.1549 0.1549
Giardia lamblia Kinase, CK1 Casein kinase 0.0216 0.0303 0.0529
Trichomonas vaginalis AGC family protein kinase 0.058 0.147 0.4544
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0171 0.0159 0.0159
Onchocerca volvulus 0.0151 0.0096 0.036
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0298 0.0566 0.0541
Echinococcus granulosus casein kinase ii subunit alpha 0.0199 0.0248 0.0248
Echinococcus granulosus lachesin 0.0332 0.0676 0.0676
Giardia lamblia Kinase, CAMK CAMKL 0.0172 0.0161 0.0068
Brugia malayi Protein kinase domain containing protein 0.0573 0.145 0.145
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0235 0.0364 0.0364
Giardia lamblia Kinase, CMGC CK2 0.0199 0.0248 0.0352
Echinococcus multilocularis raf serine:threonine protein kinase 0.0147 0.0083 0.0083
Echinococcus multilocularis Immunoglobulin 0.0597 0.1526 0.1526
Trichomonas vaginalis CAMK family protein kinase 0.0251 0.0415 0.1237
Brugia malayi Immunoglobulin domain containing protein 0.0181 0.0191 0.0191
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0171 0.0159 0.0159
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0402 0.09 0.09
Echinococcus granulosus titin 0.0235 0.0364 0.0364
Trichomonas vaginalis CMGC family protein kinase 0.0276 0.0496 0.1489
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0661 0.173 0.173
Brugia malayi Cadherin domain containing protein 0.0327 0.0661 0.0661
Schistosoma mansoni tyrosine kinase 0.0594 0.1515 0.1515
Schistosoma mansoni titin 0.0235 0.0364 0.0364
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.02 0.0253 0.0253
Echinococcus granulosus serine:threonine protein kinase mig 15 0.046 0.1086 0.1086
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0243 0.0389 0.0363
Onchocerca volvulus 0.0381 0.0834 0.3603
Leishmania major protein kinase A catalytic subunit isoform 1 0.0224 0.033 0.0304
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0151 0.0096 0.0096
Schistosoma mansoni tyrosine kinase 0.0567 0.1431 0.1431
Brugia malayi Animal haem peroxidase family protein 0.0151 0.0096 0.0096
Plasmodium falciparum apical sushi protein 0.0604 0.1549 0.1526
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0216 0.0303 0.0303
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0302 0.058 0.058
Loa Loa (eye worm) hypothetical protein 0.0151 0.0096 0.0096
Leishmania major protein kinase, putative 0.0305 0.0589 0.0563
Giardia lamblia Kinase, CMGC CLK 0.0305 0.0589 0.1461
Brugia malayi Immunoglobulin domain containing protein 0.0181 0.0191 0.0191
Entamoeba histolytica protein kinase, putative 0.0233 0.0358 0.1386
Loa Loa (eye worm) hypothetical protein 0.0181 0.0191 0.0191
Loa Loa (eye worm) TK/FER protein kinase 0.0129 0.0026 0.0026
Loa Loa (eye worm) cyclin domain-containing protein 0.0875 0.2418 0.2418
Loa Loa (eye worm) hypothetical protein 0.0151 0.0096 0.0096
Echinococcus granulosus protein jagged 1 0.0327 0.066 0.066
Echinococcus multilocularis tyrosine protein kinase Blk 0.0246 0.04 0.04
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0255 0.043 0.0404
Brugia malayi Immunoglobulin I-set domain containing protein 0.0332 0.0676 0.0676
Echinococcus granulosus hemicentin 1 0.0332 0.0676 0.0676
Trichomonas vaginalis AGC family protein kinase 0.0233 0.0358 0.1059
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0224 0.033 0.0304
Giardia lamblia NADH oxidase lateral transfer candidate 0.1122 0.3211 1
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0216 0.0303 0.0303
Echinococcus multilocularis protein kinase c epsilon type 0.0405 0.0909 0.0909
Leishmania major protein kinase, putative 0.0305 0.0589 0.0563
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0169 0.0154 0.0154
Loa Loa (eye worm) hypothetical protein 0.0327 0.066 0.066
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0299 0.0571 0.0571
Schistosoma mansoni sulfide quinone reductase 0.0298 0.0566 0.0566
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1122 0.3211 0.3192
Schistosoma mansoni notch 0.0327 0.066 0.066
Brugia malayi map kinase activated protein kinase protein 2 0.0782 0.2119 0.2119
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0332 0.0676 0.0676
Schistosoma mansoni serine/threonine protein kinase 0.0326 0.0655 0.0655
Schistosoma mansoni serine/threonine protein kinase 0.0524 0.1293 0.1293
Loa Loa (eye worm) hypothetical protein 0.0151 0.0096 0.0096
Loa Loa (eye worm) hypothetical protein 0.0181 0.0191 0.0191
Loa Loa (eye worm) hypothetical protein 0.0151 0.0096 0.0096
Entamoeba histolytica protein kinase, putative 0.0162 0.013 0.0448
Leishmania major NADH dehydrogenase, putative 0.0298 0.0566 0.0541
Echinococcus multilocularis serine:threonine protein kinase 3 0.051 0.1245 0.1245
Schistosoma mansoni serine/threonine protein kinase 0.0236 0.0367 0.0367
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0236 0.0367 0.0367
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0224 0.033 0.0304
Loa Loa (eye worm) hypothetical protein 0.0629 0.1629 0.1629
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0246 0.04 0.04
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0222 0.0322 0.0322
Schistosoma mansoni hypothetical protein 0.0151 0.0096 0.0096
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0661 0.173 0.173
Echinococcus multilocularis Immunoglobulin subtype 0.0181 0.0191 0.0191
Brugia malayi Immunoglobulin I-set domain containing protein 0.0169 0.0154 0.0154
Echinococcus multilocularis cyclin dependent kinase 5 0.0236 0.0367 0.0367
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0438 0.1017 0.1017
Leishmania major protein kinase A catalytic subunit isoform 2 0.0224 0.033 0.0304
Schistosoma mansoni cell adhesion molecule 0.0181 0.0191 0.0191
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0782 0.2119 0.2119
Entamoeba histolytica protein kinase domain containing protein 0.0276 0.0496 0.1949
Trypanosoma brucei protein kinase, putative 0.0255 0.043 0.0404
Echinococcus multilocularis transfer RNA-Phe 0.0169 0.0154 0.0154
Echinococcus multilocularis cyclin dependent kinase 0.0236 0.0367 0.0367
Schistosoma mansoni subfamily M23B non-peptidase homologue (M23 family) 0.0151 0.0096 0.0096
Echinococcus multilocularis Immunoglobulin 0.0181 0.0191 0.0191
Echinococcus multilocularis mitogen activated protein kinase 3 0.0166 0.0144 0.0144
Loa Loa (eye worm) hypothetical protein 0.0327 0.066 0.066
Brugia malayi EGF-like domain containing protein 0.0327 0.066 0.066
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0287 0.0532 0.0532
Echinococcus granulosus dual specificity protein kinase clk2 0.0305 0.0589 0.0589
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0298 0.0566 0.0445
Brugia malayi Casein kinase II, alpha chain 0.0199 0.0248 0.0248
Trichomonas vaginalis CMGC family protein kinase 0.0199 0.0248 0.0714
Loa Loa (eye worm) hypothetical protein 0.0151 0.0096 0.0096
Echinococcus granulosus tyrosine protein kinase ABL1 0.0129 0.0026 0.0026
Brugia malayi P38 map kinase family protein 2 0.0316 0.0624 0.0624
Loa Loa (eye worm) TK/ALK protein kinase 0.0299 0.0571 0.0571
Trichomonas vaginalis CAMK family protein kinase 0.0536 0.1331 0.4107
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0169 0.0154 0.0154
Loa Loa (eye worm) hypothetical protein 0.0332 0.0676 0.0676
Brugia malayi basement membrane proteoglycan precursor 0.0181 0.0191 0.0191
Brugia malayi Protein kinase domain containing protein 0.0299 0.0572 0.0572
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0298 0.0566 0.0566
Trypanosoma brucei SNF1-related protein kinases, putative 0.0155 0.0109 0.0081
Trichomonas vaginalis AGC family protein kinase 0.058 0.147 0.4544
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0298 0.0566 0.0541
Trichomonas vaginalis CMGC family protein kinase 0.0276 0.0496 0.1489
Plasmodium falciparum calcium-dependent protein kinase 3 0.02 0.0253 0.0226
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0671 0.1764 0.1764
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.1122 0.3211 1
Onchocerca volvulus 0.0169 0.0154 0.0614
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0298 0.0566 0.0541
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0276 0.0496 0.047
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0298 0.0566 0.1711
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0246 0.04 0.04
Trypanosoma cruzi casein kinase, putative 0.0216 0.0303 0.0276
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0287 0.0533 0.0533
Schistosoma mansoni protein kinase 0.0861 0.2372 0.2372
Onchocerca volvulus Peroxidasin homolog 0.0152 0.0098 0.0368
Schistosoma mansoni serine/threonine-protein kinase 0.0326 0.0656 0.0656
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.027 0.0478 0.0355
Entamoeba histolytica PH domain containing protein kinase, putative 0.0239 0.0379 0.1469
Echinococcus multilocularis tyrosine protein kinase HCK 0.0181 0.0191 0.0191
Echinococcus multilocularis titin 0.0235 0.0364 0.0364
Brugia malayi Protein kinase domain containing protein 0.0319 0.0635 0.0635
Echinococcus multilocularis casein kinase I alpha 0.0216 0.0303 0.0303
Brugia malayi Disorganized muscle protein 1 0.0151 0.0096 0.0096
Brugia malayi Protein kinase domain containing protein 0.0165 0.014 0.014
Toxoplasma gondii NADPH-glutathione reductase 0.1122 0.3211 0.3192
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0325 0.0653 0.0653
Brugia malayi hypothetical protein 0.0604 0.1549 0.1549
Trichomonas vaginalis CAMK family protein kinase 0.0155 0.0109 0.0276
Echinococcus multilocularis calcium activated potassium channel 0.0268 0.0469 0.0469
Trypanosoma cruzi polo-like protein kinase, putative 0.0536 0.1331 0.1307
Giardia lamblia Thioredoxin reductase 0.0298 0.0566 0.1388
Schistosoma mansoni hypothetical protein 0.0151 0.0096 0.0096
Echinococcus granulosus twitchin 0.0814 0.2222 0.2222
Plasmodium falciparum NIMA related kinase 1 0.027 0.0478 0.0451
Trypanosoma cruzi Protein kinase B 0.0326 0.0656 0.063
Schistosoma mansoni tyrosine kinase 0.0397 0.0883 0.0883
Schistosoma mansoni hypothetical protein 0.0327 0.066 0.066
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0612 0.1573 0.1573
Plasmodium vivax glutathione reductase, putative 0.3238 1 1
Schistosoma mansoni serine/threonine protein kinase 0.0217 0.0306 0.0306
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.1122 0.3211 0.3192
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0298 0.0566 0.0541
Echinococcus multilocularis oligomeric golgi complex subunit 3 0.0875 0.2418 0.2418
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.1122 0.3211 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0332 0.0676 0.0676
Brugia malayi Immunoglobulin I-set domain containing protein 0.0151 0.0096 0.0096
Echinococcus granulosus glutamate synthase 0.0298 0.0566 0.0566
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0416 0.0944 0.0944
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0161 0.0127 0.01
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0166 0.0144 0.0117
Loa Loa (eye worm) one IG domain family member 0.0151 0.0096 0.0096
Brugia malayi Protein kinase domain containing protein 0.0728 0.1945 0.1945
Treponema pallidum NADH oxidase 0.1122 0.3211 1
Schistosoma mansoni serine/threonine kinase 0.0447 0.1044 0.1044
Echinococcus granulosus neurogenic locus notch protein 0.0327 0.066 0.066
Giardia lamblia Kinase, NEK 0.027 0.0478 0.1099
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0233 0.0358 0.1386
Echinococcus multilocularis titin 0.0151 0.0096 0.0096
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0222 0.0322 0.0295
Brugia malayi Immunoglobulin I-set domain containing protein 0.0238 0.0375 0.0375
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.1173 0.3373 0.3373
Trichomonas vaginalis CMGC family protein kinase 0.0199 0.0248 0.0714
Schistosoma mansoni hypothetical protein 0.0151 0.0096 0.0096
Plasmodium vivax serine/threonine kinase-1, putative 0.0305 0.0589 0.0468
Schistosoma mansoni growth factor receptor-bound protein 0.0123 0.0006 0.0006
Trichomonas vaginalis AGC family protein kinase 0.058 0.147 0.4544
Onchocerca volvulus 0.0619 0.1597 0.696
Echinococcus granulosus Immunoglobulin 0.0597 0.1526 0.1526
Leishmania major dihydrolipoamide dehydrogenase, putative 0.1122 0.3211 0.3192
Brugia malayi STE20-like kinase MST 0.051 0.1245 0.1245
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0298 0.0566 0.0566
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1122 0.3211 0.3192
Brugia malayi Fibronectin type III domain containing protein 0.0615 0.1584 0.1584
Schistosoma mansoni serine/threonine protein kinase 0.0224 0.033 0.033
Schistosoma mansoni serine/threonine-protein kinase 0.0326 0.0656 0.0656
Echinococcus granulosus nervana 2 0.0245 0.0398 0.0398
Echinococcus granulosus mitogen activated protein kinase 14 0.0316 0.0624 0.0624
Brugia malayi GCC2 and GCC3 family protein 0.0931 0.2599 0.2599
Loa Loa (eye worm) hypothetical protein 0.0615 0.1584 0.1584
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.02 0.0253 0.0253
Echinococcus granulosus cyclin dependent kinase 1 0.0236 0.0367 0.0367
Schistosoma mansoni hypothetical protein 0.0151 0.0096 0.0096
Echinococcus granulosus roundabout 2 0.035 0.0734 0.0734
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1122 0.3211 0.3192
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0155 0.0109 0.0081
Loa Loa (eye worm) hypothetical protein 0.0236 0.0368 0.0368
Echinococcus granulosus slit 2 protein 0.0371 0.0801 0.0801
Brugia malayi Protein kinase domain containing protein 0.0383 0.0838 0.0838
Plasmodium vivax ferrodoxin reductase, putative 0.0298 0.0566 0.0445
Echinococcus granulosus neuroglian 0.0748 0.2012 0.2012
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0247 0.0404 0.0378
Entamoeba histolytica PH domain containing protein kinase, putative 0.0326 0.0656 0.2607
Entamoeba histolytica casein kinase, putative 0.0216 0.0303 0.1157
Brugia malayi Immunoglobulin I-set domain containing protein 0.0195 0.0237 0.0237
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0441 0.1025 0.1025
Trichomonas vaginalis CAMK family protein kinase 0.0155 0.0109 0.0276
Echinococcus granulosus c-Jun N-terminal kinases 0.0524 0.1293 0.1293
Loa Loa (eye worm) hypothetical protein 0.0151 0.0096 0.0096
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.02 0.0253 0.0226
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase 0.0159 0.0121 0.0121
Loa Loa (eye worm) hypothetical protein 0.0615 0.1584 0.1584
Loa Loa (eye worm) AGC/NDR protein kinase 0.0319 0.0635 0.0635
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0629 0.1629 0.1629
Loa Loa (eye worm) hypothetical protein 0.0177 0.0179 0.0179
Echinococcus granulosus protein kinase shaggy 0.0255 0.043 0.043
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0298 0.0566 0.0541
Schistosoma mansoni protein kinase 0.0199 0.0248 0.0248
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1122 0.3211 0.3192
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0224 0.033 0.0304
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.035 0.0734 0.0734
Loa Loa (eye worm) hypothetical protein 0.0169 0.0154 0.0154
Trypanosoma cruzi cdc2-related kinase 3 0.0236 0.0367 0.0341
Toxoplasma gondii CMGC kinase, CK2 family 0.0199 0.0248 0.0222
Echinococcus multilocularis roundabout 2 0.035 0.0734 0.0734
Schistosoma mansoni septate junction protein 0.0332 0.0676 0.0676
Giardia lamblia Kinase, CAMK CAMKL 0.0172 0.0161 0.0068
Trypanosoma cruzi cdc2-related kinase 1 0.0236 0.0367 0.0341
Loa Loa (eye worm) hypothetical protein 0.0283 0.0519 0.0519
Echinococcus multilocularis casein kinase I alpha 0.0216 0.0303 0.0303
Schistosoma mansoni tyrosine kinase 0.0359 0.0764 0.0764
Echinococcus granulosus serine:threonine kinase SAD 1 0.0155 0.0109 0.0109
Trypanosoma brucei NADH dehydrogenase 0.0298 0.0566 0.0541
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0398 0.0888 0.0888
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.1122 0.3211 0.2803
Onchocerca volvulus 0.0235 0.0364 0.1538
Echinococcus granulosus activin receptor type 0.013 0.0027 0.0027
Echinococcus multilocularis contactin neuroglian septate junction protein 0.035 0.0734 0.0734
Schistosoma mansoni serine/threonine protein kinase 0.0236 0.0367 0.0367
Brugia malayi SH2 domain containing protein 0.0431 0.0994 0.0994
Echinococcus granulosus N chimaerin 0.0148 0.0086 0.0086
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.02 0.0253 0.0128
Schistosoma mansoni septate junction protein 0.0181 0.0191 0.0191
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0298 0.0566 0.2239
Loa Loa (eye worm) hypothetical protein 0.0332 0.0676 0.0676
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1122 0.3211 0.3192
Entamoeba histolytica protein kinase, putative 0.0143 0.0069 0.0198
Entamoeba histolytica protein kinase, putative 0.0165 0.014 0.049
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0181 0.0191 0.0191
Echinococcus multilocularis 0.0239 0.0379 0.0379
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.1122 0.3211 1
Onchocerca volvulus 0.0366 0.0786 0.3391
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0311 0.0608 0.0608
Loa Loa (eye worm) TK/ABL protein kinase 0.0129 0.0026 0.0026
Entamoeba histolytica protein kinase domain containing protein 0.0255 0.043 0.168
Entamoeba histolytica protein kinase, putative 0.0233 0.0358 0.1386
Entamoeba histolytica protein kinase, putative 0.02 0.0253 0.0953
Schistosoma mansoni nephrin related 0.0151 0.0096 0.0096
Entamoeba histolytica disulphide oxidoreductase, putative 0.0298 0.0566 0.2239
Echinococcus multilocularis tyrosine protein kinase Abl 0.0186 0.0206 0.0206
Echinococcus granulosus protein jagged 2 0.0327 0.066 0.066
Onchocerca volvulus 0.0275 0.0494 0.2108
Trypanosoma brucei Casein kinase II 0.0199 0.0248 0.0222
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0172 0.0161 0.0035
Echinococcus multilocularis serine threonine protein kinase 0.0401 0.0896 0.0896
Schistosoma mansoni hypothetical protein 0.0151 0.0096 0.0096
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0171 0.0159 0.0159
Trypanosoma brucei casein kinase I, isoform 2 0.0216 0.0303 0.0276
Brugia malayi Immunoglobulin I-set domain containing protein 0.0332 0.0676 0.0676
Brugia malayi Immunoglobulin I-set domain containing protein 0.0169 0.0154 0.0154
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0402 0.09 0.09
Loa Loa (eye worm) hypothetical protein 0.0327 0.066 0.066
Echinococcus granulosus titin 0.0235 0.0364 0.0364
Entamoeba histolytica protein kinase domain containing protein 0.0159 0.0121 0.0412
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0298 0.0566 0.0541
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.1868 0.5604 0.5604
Echinococcus granulosus down syndrome cell adhesion 0.0151 0.0096 0.0096
Schistosoma mansoni hypothetical protein 0.0181 0.0191 0.0191
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0326 0.0655 0.0655
Schistosoma mansoni serine/threonine protein kinase 0.0268 0.0469 0.0469
Echinococcus multilocularis protein jagged 1 0.0327 0.066 0.066
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0304 0.0586 0.0586
Loa Loa (eye worm) hypothetical protein 0.0222 0.0322 0.0322
Schistosoma mansoni ephrin receptor 0.0191 0.0224 0.0224
Schistosoma mansoni hypothetical protein 0.0202 0.0259 0.0259
Brugia malayi Protein kinase domain containing protein 0.0129 0.0026 0.0026
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0861 0.2372 0.2372
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0298 0.0566 0.0566
Brugia malayi Heparan sulfate 0.0181 0.0191 0.0191
Echinococcus granulosus tyrosine protein kinase HCK 0.0181 0.0191 0.0191
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.1122 0.3211 0.3192
Onchocerca volvulus Neurogenic locus notch homolog 0.0327 0.066 0.2841
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.1122 0.3211 0.3192
Schistosoma mansoni glutamate synthase 0.0298 0.0566 0.0566
Loa Loa (eye worm) hypothetical protein 0.0327 0.066 0.066
Brugia malayi Protein kinase c protein 2 0.023 0.0347 0.0347
Trypanosoma brucei rac serine-threonine kinase, putative 0.058 0.147 0.1447
Trypanosoma brucei polo-like protein kinase 0.0536 0.1331 0.1307
Schistosoma mansoni hypothetical protein 0.0327 0.0661 0.0661
Trypanosoma brucei hypothetical protein, conserved 0.0298 0.0566 0.0541
Trichomonas vaginalis CAMK family protein kinase 0.0228 0.0344 0.1012
Onchocerca volvulus 0.0129 0.0026 0.0052
Trichomonas vaginalis CMGC family protein kinase 0.0166 0.0144 0.0387
Schistosoma mansoni serine/threonine protein kinase 0.0423 0.0968 0.0968
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0216 0.0303 0.0276
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0233 0.0358 0.0358
Schistosoma mansoni protein kinase 0.0728 0.1945 0.1945
Loa Loa (eye worm) TK/FER protein kinase 0.0129 0.0026 0.0026
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0302 0.058 0.058
Schistosoma mansoni titin 0.0151 0.0096 0.0096
Brugia malayi Protein kinase domain containing protein 0.0129 0.0026 0.0026
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0311 0.0608 0.0608
Echinococcus multilocularis fat cadherin tumor suppressor 0.0327 0.0661 0.0661
Entamoeba histolytica serine/threonine protein kinase, putative 0.0536 0.1331 0.5376
Trichomonas vaginalis CAMK family protein kinase 0.0553 0.1383 0.4272
Mycobacterium ulcerans flavoprotein disulfide reductase 0.1122 0.3211 1
Loa Loa (eye worm) hypothetical protein 0.0181 0.0191 0.0191
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0233 0.0358 0.0235
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0222 0.0322 0.0322
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0236 0.0367 0.0367
Echinococcus multilocularis hemicentin 1 0.0332 0.0676 0.0676
Loa Loa (eye worm) cyclin C 0.1749 0.5222 0.5222
Trichomonas vaginalis CAMK family protein kinase 0.0155 0.0109 0.0276
Echinococcus multilocularis mitogen activated protein kinase 11 0.0316 0.0624 0.0624
Echinococcus granulosus tyrosine protein kinase Src42A 0.0184 0.02 0.02
Brugia malayi protein unc-22 0.0235 0.0364 0.0364
Schistosoma mansoni serine/threonine protein kinase 0.0155 0.0109 0.0109
Schistosoma mansoni vav2 0.0163 0.0134 0.0134
Loa Loa (eye worm) Notch2 0.0327 0.066 0.066
Plasmodium falciparum glycogen synthase kinase 3 0.0255 0.043 0.0404
Loa Loa (eye worm) hypothetical protein 0.0598 0.1528 0.1528
Onchocerca volvulus 0.0604 0.1549 0.6748
Brugia malayi putative serine/threonine kinase SADA gamma 0.0155 0.0109 0.0109
Loa Loa (eye worm) projectin 0.0169 0.0154 0.0154
Loa Loa (eye worm) TK/KIN16 protein kinase 0.1461 0.4299 0.4299
Onchocerca volvulus Putative titin 0.0151 0.0096 0.036
Giardia lamblia Kinase, CMGC CDK 0.0236 0.0367 0.074
Loa Loa (eye worm) casein kinase 0.0358 0.0758 0.0758
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0383 0.0838 0.0838
Brugia malayi Immunoglobulin I-set domain containing protein 0.035 0.0734 0.0734
Trypanosoma cruzi cdc2-related kinase 1 0.0236 0.0367 0.0341
Echinococcus multilocularis casein kinase I alpha 0.0216 0.0303 0.0303
Loa Loa (eye worm) hypothetical protein 0.0929 0.2591 0.2591
Echinococcus multilocularis NCK adaptor protein 0.0123 0.0006 0.0006
Echinococcus multilocularis roundabout 2 0.035 0.0734 0.0734
Schistosoma mansoni titin 0.0332 0.0676 0.0676
Echinococcus multilocularis dual specificity 0.0276 0.0496 0.0496
Echinococcus multilocularis titin 0.0151 0.0096 0.0096
Brugia malayi EGF-like domain containing protein 0.0327 0.066 0.066
Echinococcus multilocularis epidermal growth factor receptor 0.0477 0.1142 0.1142
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0276 0.0496 0.0496
Echinococcus multilocularis mitogen activated protein kinase 0.0166 0.0144 0.0144
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.1122 0.3211 0.3192
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.02 0.0253 0.0128
Schistosoma mansoni basigin related 0.0181 0.0191 0.0191
Loa Loa (eye worm) hypothetical protein 0.0597 0.1526 0.1526
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.1122 0.3211 0.3192
Echinococcus granulosus tyrosine kinase 0.0246 0.04 0.04
Echinococcus granulosus leucine rich repeats and immunoglobulin 0.0152 0.0098 0.0098
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0319 0.0635 0.0635
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0222 0.0322 0.0322
Trichomonas vaginalis AGC family protein kinase 0.058 0.147 0.4544
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0298 0.0566 0.2239
Echinococcus granulosus dual specificity 0.0276 0.0496 0.0496
Echinococcus multilocularis down syndrome cell adhesion 0.0151 0.0096 0.0096
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.1122 0.3211 0.3192
Schistosoma mansoni g1/s-specific cyclin C 0.1749 0.5222 0.5222
Brugia malayi Immunoglobulin I-set domain containing protein 0.0151 0.0096 0.0096
Echinococcus multilocularis aurora kinase A 0.0233 0.0358 0.0358
Echinococcus multilocularis cyclin 0.0875 0.2418 0.2418
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0298 0.0566 0.1711
Echinococcus granulosus tyrosine protein kinase Fyn 0.0302 0.058 0.058
Loa Loa (eye worm) CAMK protein kinase 0.0235 0.0364 0.0364
Brugia malayi Furin-like cysteine rich region family protein 0.0684 0.1806 0.1806
Brugia malayi Kinase associated domain 1 family protein 0.0202 0.0259 0.0259
Echinococcus granulosus insulin growth factor binding 0.0151 0.0096 0.0096
Loa Loa (eye worm) hypothetical protein 0.0129 0.0026 0.0026
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0305 0.0589 0.0563
Echinococcus multilocularis neurogenic locus notch protein 0.0327 0.066 0.066
Trichomonas vaginalis CMGC family protein kinase 0.0178 0.0182 0.0507
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0298 0.0566 0.0566
Schistosoma mansoni hypothetical protein 0.0202 0.0259 0.0259
Echinococcus multilocularis cyclin dependent kinase 1 0.0236 0.0367 0.0367
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0166 0.0144 0.0117
Loa Loa (eye worm) hypothetical protein 0.0929 0.2591 0.2591
Onchocerca volvulus 0.0298 0.0566 0.2428
Schistosoma mansoni protein kinase C mu 0.0432 0.0996 0.0996
Trichomonas vaginalis CAMK family protein kinase 0.043 0.0992 0.3044
Schistosoma mansoni serine/threonine protein kinase 0.0429 0.0986 0.0986
Loa Loa (eye worm) hypothetical protein 0.0127 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0371 0.0801 0.0801
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0255 0.043 0.043
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0181 0.0191 0.0191
Schistosoma mansoni basigin related 0.0181 0.0191 0.0191
Trichomonas vaginalis CAMK family protein kinase 0.0155 0.0109 0.0276
Loa Loa (eye worm) hypothetical protein 0.0327 0.0661 0.0661
Echinococcus granulosus casein kinase I alpha 0.0216 0.0303 0.0303
Brugia malayi hypothetical protein 0.0441 0.1025 0.1025
Trichomonas vaginalis CAMK family protein kinase 0.0155 0.0109 0.0276
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.0981 0.2757 0.2757
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0148 0.0086 0.0086
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0181 0.0191 0.0191
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0151 0.0096 0.0096
Onchocerca volvulus 0.0127 0.0018 0.0017
Onchocerca volvulus 0.0129 0.0026 0.0052
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0612 0.1573 0.1573
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0298 0.0566 0.1388
Echinococcus granulosus serine:threonine protein kinase 0.0226 0.0337 0.0337
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0167 0.0145 0.0118
Loa Loa (eye worm) TK protein kinase 0.0511 0.1249 0.1249
Trichomonas vaginalis CAMK family protein kinase 0.0155 0.0109 0.0276
Echinococcus granulosus casein kinase I gamma 0.0423 0.0968 0.0968
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0298 0.0566 0.1711
Entamoeba histolytica protein kinase, putative 0.0243 0.0389 0.1512
Echinococcus multilocularis Immunoglobulin 0.0597 0.1526 0.1526
Brugia malayi hypothetical protein 0.0604 0.1549 0.1549
Echinococcus multilocularis casein kinase I gamma 0.0423 0.0968 0.0968
Giardia lamblia Aurora kinase 0.0233 0.0358 0.0711
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0129 0.0026 0.0022
Schistosoma mansoni serine/threonine protein kinase 0.0483 0.1162 0.1162
Trypanosoma cruzi casein kinase, putative 0.0216 0.0303 0.0276
Plasmodium falciparum glutathione reductase 0.3238 1 1
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0782 0.2119 0.2119
Schistosoma mansoni cell adhesion molecule 0.0151 0.0096 0.0096
Echinococcus granulosus Glutaredoxin protein 5 0.0245 0.0398 0.0398
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0302 0.058 0.058
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.046 0.1088 0.1088
Echinococcus multilocularis notch 0.0327 0.066 0.066
Onchocerca volvulus 0.0327 0.066 0.2841
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0276 0.0496 0.0496
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0186 0.0206 0.0206
Entamoeba histolytica protein kinase domain containing protein 0.013 0.0027 0.0027
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0155 0.0109 0.0081
Schistosoma mansoni tyrosine kinase 0.0684 0.1806 0.1806
Echinococcus granulosus Opioid binding protein:cell adhesion molecule 0.0151 0.0096 0.0096
Echinococcus multilocularis neurogenic locus notch protein 4 0.0327 0.066 0.066
Schistosoma mansoni netrin receptor unc5 0.0181 0.0191 0.0191
Trichomonas vaginalis CK1 family protein kinase 0.0216 0.0303 0.0884
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0216 0.0303 0.0303
Echinococcus multilocularis cell adhesion molecule:down regulated by 0.0181 0.0191 0.0191
Schistosoma mansoni serine/threonine protein kinase 0.0178 0.0182 0.0182
Schistosoma mansoni serine/threonine protein kinase 0.0233 0.0358 0.0358
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0305 0.0589 0.0563
Schistosoma mansoni protein kinase 0.0171 0.0159 0.0159
Loa Loa (eye worm) programmed cell death 8 0.0298 0.0566 0.0566
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0298 0.0566 0.0541
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0151 0.0096 0.0096
Echinococcus granulosus casein kinase I alpha 0.0216 0.0303 0.0303
Schistosoma mansoni protein kinase 0.0171 0.0159 0.0159
Echinococcus granulosus casein kinase i 0.0216 0.0303 0.0303
Schistosoma mansoni serine/threonine protein kinase 0.0162 0.013 0.013
Brugia malayi Immunoglobulin domain containing protein 0.0181 0.0191 0.0191
Brugia malayi protein-tyrosine kinase 0.0246 0.04 0.04
Loa Loa (eye worm) hypothetical protein 0.0532 0.1316 0.1316
Loa Loa (eye worm) hypothetical protein 0.0672 0.1767 0.1767
Echinococcus granulosus cyclin dependent kinase 5 0.0236 0.0367 0.0367
Loa Loa (eye worm) hypothetical protein 0.0151 0.0096 0.0096
Brugia malayi Immunoglobulin I-set domain containing protein 0.0151 0.0096 0.0096
Schistosoma mansoni titin 0.0169 0.0154 0.0154
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0699 0.1854 0.1854
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0326 0.0656 0.063
Schistosoma mansoni kinase 0.0573 0.1448 0.1448
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0171 0.0159 0.0159
Loa Loa (eye worm) hypothetical protein 0.0332 0.0676 0.0676
Echinococcus multilocularis calcium dependent protein kinase 0.0135 0.0043 0.0043
Trichomonas vaginalis CMGC family protein kinase 0.0305 0.0589 0.1781
Loa Loa (eye worm) hypothetical protein 0.0327 0.066 0.066
Loa Loa (eye worm) hypothetical protein 0.0327 0.066 0.066
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0398 0.0888 0.0888
Schistosoma mansoni notch 0.0327 0.066 0.066
Schistosoma mansoni serine/threonine protein kinase 0.0155 0.0109 0.0109
Echinococcus granulosus cGMP dependent protein kinase 1 0.0167 0.0145 0.0145
Loa Loa (eye worm) hypothetical protein 0.0358 0.076 0.076
Trichomonas vaginalis CAMK family protein kinase 0.02 0.0253 0.0728
Schistosoma mansoni slit 0.0152 0.0098 0.0098
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0224 0.033 0.033
Brugia malayi Protein kinase domain containing protein 0.0423 0.0968 0.0968
Trichomonas vaginalis CAMK family protein kinase 0.0155 0.0109 0.0276
Echinococcus granulosus tyrosine protein kinase shark 0.0342 0.0707 0.0707
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0298 0.0566 0.0566
Loa Loa (eye worm) TK/FER protein kinase 0.0129 0.0026 0.0026
Brugia malayi Immunoglobulin I-set domain containing protein 0.0151 0.0096 0.0096
Onchocerca volvulus 0.0255 0.043 0.1828
Loa Loa (eye worm) animal heme peroxidase 0.0151 0.0096 0.0096
Loa Loa (eye worm) hypothetical protein 0.0222 0.0322 0.0322
Brugia malayi notch-like transmembrane receptor 0.0327 0.066 0.066
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0165 0.014 0.0113
Loa Loa (eye worm) hypothetical protein 0.0604 0.1549 0.1549
Schistosoma mansoni serine/threonine protein kinase 0.0216 0.0303 0.0303
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0486 0.117 0.117
Trichomonas vaginalis CAMK family protein kinase 0.0251 0.0415 0.1237
Trichomonas vaginalis CAMK family protein kinase 0.0536 0.1331 0.4107
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0824 0.2255 0.2255
Trichomonas vaginalis CMGC family protein kinase 0.0276 0.0496 0.1489
Loa Loa (eye worm) TK protein kinase 0.0366 0.0785 0.0785
Echinococcus multilocularis expressed protein 0.0165 0.014 0.014
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0536 0.1331 0.1331
Onchocerca volvulus 0.0151 0.0096 0.036
Brugia malayi Peroxidasin 0.0333 0.0678 0.0678
Trichomonas vaginalis CMGC family protein kinase 0.0166 0.0144 0.0387
Schistosoma mansoni notch 0.0327 0.066 0.066
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.3238 1 1
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.02 0.0253 0.0253
Loa Loa (eye worm) hypothetical protein 0.0604 0.1549 0.1549
Brugia malayi Protein kinase domain containing protein 0.1173 0.3373 0.3373
Schistosoma mansoni hypothetical protein 0.0181 0.0191 0.0191
Brugia malayi Immunoglobulin I-set domain containing protein 0.0332 0.0676 0.0676
Entamoeba histolytica thioredoxin reductase, putative 0.0298 0.0566 0.2239
Schistosoma mansoni serine/threonine protein kinase 0.0268 0.0469 0.0469
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0451 0.1057 0.1057
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0316 0.0624 0.0624
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0155 0.0109 0.0109
Brugia malayi kettin 0.0151 0.0096 0.0096
Schistosoma mansoni vesicular amine transporter 0.0597 0.1526 0.1526
Leishmania major hypothetical protein, conserved 0.0298 0.0566 0.0541
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0699 0.1854 0.1854
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0151 0.0096 0.0096
Schistosoma mansoni serine/threonine protein kinase 0.0319 0.0635 0.0635
Loa Loa (eye worm) hypothetical protein 0.0151 0.0096 0.0096
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0224 0.033 0.033
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0298 0.0566 0.1711
Echinococcus multilocularis c src tyrosine kinase 0.0186 0.0206 0.0206
Trichomonas vaginalis CMGC family protein kinase 0.0236 0.0367 0.1086
Brugia malayi Protein kinase domain containing protein 0.0398 0.0889 0.0889
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0236 0.0367 0.0367
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0276 0.0496 0.047
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0276 0.0496 0.047
Schistosoma mansoni serine/threonine protein kinase 0.0166 0.0144 0.0144
Trichomonas vaginalis AGC family protein kinase 0.034 0.0701 0.2131
Schistosoma mansoni protein kinase 0.0383 0.0838 0.0838
Plasmodium falciparum protein kinase 5 0.0236 0.0367 0.0341
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0431 0.0994 0.0994
Echinococcus granulosus calcium activated potassium channel 0.0268 0.0469 0.0469
Brugia malayi Immunoglobulin I-set domain containing protein 0.035 0.0734 0.0734
Loa Loa (eye worm) TK/FER protein kinase 0.0129 0.0026 0.0026
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0155 0.0109 0.0081
Schistosoma mansoni serine/threonine protein kinase 0.0155 0.0109 0.0109
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0298 0.0566 0.0541
Loa Loa (eye worm) hypothetical protein 0.0298 0.0566 0.0566
Echinococcus multilocularis epidermal growth factor receptor 0.0684 0.1806 0.1806
Trichomonas vaginalis CMGC family protein kinase 0.0166 0.0144 0.0387
Giardia lamblia Glutamate synthase 0.0298 0.0566 0.1388
Echinococcus multilocularis low density lipoprotein receptor (ldl) 0.0181 0.0191 0.0191
Brugia malayi hypothetical protein 0.0604 0.1549 0.1549
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0311 0.0608 0.0582
Echinococcus multilocularis insulin growth factor binding 0.0151 0.0096 0.0096
Schistosoma mansoni serine/threonine kinase 0.0319 0.0635 0.0635
Loa Loa (eye worm) AUR protein kinase 0.0233 0.0358 0.0358
Echinococcus multilocularis serine:threonine protein kinase 38 0.0319 0.0635 0.0635
Echinococcus granulosus casein kinase I delta 0.0216 0.0303 0.0303
Entamoeba histolytica protein kinase domain containing protein 0.0243 0.0389 0.1512
Echinococcus multilocularis fibropellin Ia 0.0327 0.066 0.066
Schistosoma mansoni serine/threonine protein kinase 0.0165 0.014 0.014
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0302 0.058 0.058
Echinococcus granulosus expressed protein 0.0165 0.014 0.014
Trichomonas vaginalis AGC family protein kinase 0.0233 0.0358 0.1059
Schistosoma mansoni glutamate synthase 0.0298 0.0566 0.0566
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0305 0.0589 0.0563
Schistosoma mansoni cell adhesion molecule 0.0169 0.0154 0.0154
Brugia malayi Protein kinase domain containing protein 0.0305 0.0589 0.0589
Trichomonas vaginalis CAMK family protein kinase 0.0536 0.1331 0.4107
Schistosoma mansoni titin 0.0151 0.0096 0.0096
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.043 0.0992 0.0992
Giardia lamblia Kinase, CMGC DYRK 0.0276 0.0496 0.1158
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0224 0.033 0.0304
Brugia malayi Immunoglobulin I-set domain containing protein 0.0181 0.0192 0.0192
Schistosoma mansoni serine/threonine protein kinase 0.0167 0.0145 0.0145
Toxoplasma gondii casein kinase I 0.0216 0.0303 0.0276
Onchocerca volvulus Serine\/threonine kinase homolog 0.0536 0.1331 0.5788
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0228 0.0344 0.0344
Brugia malayi Delta serrate ligand family protein 0.0327 0.066 0.066
Echinococcus multilocularis CDC7 cell division cycle 7 0.0178 0.0182 0.0182
Echinococcus granulosus protein tyrosine kinase 0.0567 0.1431 0.1431
Onchocerca volvulus 0.015 0.0092 0.0344
Echinococcus multilocularis serine:threonine protein kinase 0.0226 0.0337 0.0337
Echinococcus multilocularis cyclin dependent kinase 9 0.0175 0.0174 0.0174
Trichomonas vaginalis STE family protein kinase 0.027 0.0478 0.1432
Entamoeba histolytica protein kinase domain containing protein 0.0402 0.09 0.361
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0728 0.1945 0.1945
Brugia malayi Protein kinase domain containing protein 0.1868 0.5604 0.5604
Loa Loa (eye worm) hypothetical protein 0.0155 0.0109 0.0109
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0298 0.0566 0.1711
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0327 0.066 0.2841
Echinococcus granulosus tyrosine protein kinase Srms 0.0535 0.1326 0.1326
Echinococcus multilocularis PAK box P21 Rho binding 0.0128 0.0021 0.0021
Trypanosoma cruzi casein kinase, delta isoform, putative 0.015 0.0092 0.0065
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0402 0.09 0.09
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0305 0.0589 0.0563
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0255 0.043 0.043
Loa Loa (eye worm) hypothetical protein 0.0367 0.0787 0.0787
Loa Loa (eye worm) hypothetical protein 0.0151 0.0096 0.0096
Echinococcus granulosus cyclin dependent kinase 0.0236 0.0367 0.0367
Schistosoma mansoni laminin gamma-3 chain 0.0327 0.066 0.066
Echinococcus multilocularis twitchin 0.0217 0.0306 0.0306
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.027 0.0478 0.0451
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0167 0.0145 0.0145
Loa Loa (eye worm) thyroid receptor interactor 0.0203 0.0261 0.0261
Echinococcus granulosus mitogen activated protein kinase 0.0166 0.0144 0.0144
Echinococcus granulosus titin 0.0151 0.0096 0.0096
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0255 0.043 0.043
Loa Loa (eye worm) hypothetical protein 0.017 0.0157 0.0157
Loa Loa (eye worm) hypothetical protein 0.0327 0.066 0.066
Trichomonas vaginalis STE family protein kinase 0.0171 0.0159 0.0432
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0162 0.013 0.013
Schistosoma mansoni serine/threonine protein kinase 0.0224 0.033 0.033
Trichomonas vaginalis CMGC family protein kinase 0.0199 0.0248 0.0714
Echinococcus granulosus c src tyrosine kinase 0.0186 0.0206 0.0206
Echinococcus granulosus CDC7 cell division cycle 7 0.0178 0.0182 0.0182
Schistosoma mansoni cell adhesion molecule 0.0796 0.2164 0.2164
Trichomonas vaginalis glutamate synthase, putative 0.0298 0.0566 0.1711
Brugia malayi MAP kinase sur-1 0.0166 0.0144 0.0144
Echinococcus granulosus delta-like protein 1 0.0327 0.066 0.066
Onchocerca volvulus Tyrosine kinase homolog 0.0835 0.2289 1
Echinococcus granulosus serine:threonine protein kinase 3 0.051 0.1245 0.1245
Entamoeba histolytica protein kinase, putative 0.0181 0.0191 0.0697
Loa Loa (eye worm) glutathione reductase 0.3238 1 1
Onchocerca volvulus 0.0222 0.0322 0.1352
Loa Loa (eye worm) hypothetical protein 0.0181 0.0191 0.0191
Schistosoma mansoni roundabout 0.0332 0.0676 0.0676
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0441 0.1025 0.1025
Onchocerca volvulus 0.0129 0.0026 0.0052
Schistosoma mansoni serine/threonine protein kinase 0.0405 0.0909 0.0909
Onchocerca volvulus 0.0151 0.0096 0.036
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0438 0.1017 0.1017
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.1122 0.3211 0.3192
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.02 0.0253 0.0253
Schistosoma mansoni protein kinase 0.013 0.0027 0.0027
Echinococcus multilocularis thioredoxin glutathione reductase 0.3238 1 1
Schistosoma mansoni protein kinase 0.0233 0.0358 0.0358
Echinococcus granulosus protein jagged 2 0.0327 0.066 0.066
Brugia malayi hypothetical protein 0.0604 0.1549 0.1549
Plasmodium falciparum serine/threonine protein kinase, putative 0.0233 0.0358 0.0332
Echinococcus multilocularis dual specificity protein kinase clk2 0.0305 0.0589 0.0589
Plasmodium vivax unspecified product 0.0199 0.0248 0.0123
Toxoplasma gondii thioredoxin reductase 0.3238 1 1
Echinococcus multilocularis insulin receptor 0.0594 0.1515 0.1515
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0148 0.0086 0.0086
Brugia malayi Immunoglobulin I-set domain containing protein 0.0169 0.0154 0.0154
Trypanosoma brucei aurora B kinase 0.0233 0.0358 0.0332
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0171 0.0159 0.0159
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0166 0.0144 0.0117
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0155 0.0109 0.0081
Plasmodium vivax serine/threonine protein kinase, putative 0.0165 0.014 0.0013
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0216 0.0302 0.0302
Entamoeba histolytica hypothetical protein 0.0243 0.0389 0.1512
Brugia malayi Protein kinase domain containing protein 0.0629 0.1629 0.1629
Echinococcus multilocularis tyrosine protein kinase otk 0.0332 0.0676 0.0676
Echinococcus multilocularis 0.0304 0.0586 0.0586
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.051 0.1245 0.1245
Echinococcus multilocularis tyrosine protein kinase Srms 0.0246 0.04 0.04
Schistosoma mansoni serine/threonine protein kinase 0.0243 0.0389 0.0389
Brugia malayi serine/threonine-protein kinase PAK 7 0.046 0.1088 0.1088
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0311 0.0608 0.0582
Brugia malayi basement membrane proteoglycan 0.0181 0.0191 0.0191
Loa Loa (eye worm) notch protein 0.0327 0.066 0.066
Trichomonas vaginalis AGC family protein kinase 0.0355 0.0749 0.2282
Trichomonas vaginalis CAMK family protein kinase 0.0226 0.0337 0.0993
Loa Loa (eye worm) hypothetical protein 0.0327 0.066 0.066
Brugia malayi SRC-1 0.0302 0.058 0.058
Echinococcus granulosus contactin 0.035 0.0734 0.0734
Echinococcus granulosus protein jagged 1 0.0327 0.066 0.066
Brugia malayi Temporarily assigned gene name protein 59 0.0222 0.0322 0.0322
Schistosoma mansoni hypothetical protein 0.0169 0.0154 0.0154
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0402 0.09 0.09
Loa Loa (eye worm) TK/FAK protein kinase 0.0573 0.145 0.145
Trichomonas vaginalis CMGC family protein kinase 0.0199 0.0248 0.0714
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0332 0.0676 0.291
Echinococcus granulosus neurogenic locus protein delta 0.0327 0.066 0.066
Echinococcus multilocularis Opioid binding protein:cell adhesion molecule 0.0151 0.0096 0.0096
Schistosoma mansoni serine/threonine protein kinase 0.0466 0.1106 0.1106
Entamoeba histolytica serine/threonine protein kinase, putative 0.0155 0.0109 0.0361
Loa Loa (eye worm) hypothetical protein 0.0604 0.1549 0.1549
Loa Loa (eye worm) hypothetical protein 0.0238 0.0375 0.0375
Trypanosoma cruzi trypanothione reductase, putative 0.3238 1 1
Echinococcus multilocularis titin 0.0151 0.0096 0.0096
Echinococcus multilocularis activin receptor type 0.013 0.0027 0.0027
Trichomonas vaginalis CAMK family protein kinase 0.0228 0.0344 0.1012
Echinococcus granulosus serine:threonine protein kinase N2 0.0257 0.0436 0.0436
Trichomonas vaginalis CMGC family protein kinase 0.0255 0.043 0.1283
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0298 0.0566 0.1711
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0181 0.0191 0.0191
Loa Loa (eye worm) hypothetical protein 0.0151 0.0096 0.0096
Brugia malayi serine/threonine-protein kinase 6 0.0233 0.0358 0.0358
Trichomonas vaginalis CAMK family protein kinase 0.0155 0.0109 0.0276
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0298 0.0566 0.0541
Leishmania major protein kinase, putative 0.02 0.0253 0.0226
Echinococcus granulosus low density lipoprotein receptor ldl 0.0181 0.0191 0.0191
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0349 0.073 0.073
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0629 0.1629 0.1629
Echinococcus multilocularis expressed conserved protein 0.0167 0.0145 0.0145
Schistosoma mansoni hypothetical protein 0.0181 0.0191 0.0191
Schistosoma mansoni hypothetical protein 0.0327 0.066 0.066
Brugia malayi Immunoglobulin I-set domain containing protein 0.0151 0.0096 0.0096
Loa Loa (eye worm) hypothetical protein 0.0275 0.0494 0.0494
Trichomonas vaginalis AGC family protein kinase 0.0178 0.0182 0.0507
Echinococcus multilocularis c4b binding protein beta chain 0.0604 0.1549 0.1549
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.1122 0.3211 0.3124
Brugia malayi Cyclin C 0.1749 0.5222 0.5222
Trypanosoma cruzi trypanothione reductase, putative 0.1122 0.3211 0.3192
Brugia malayi Doublecortin family protein 0.0299 0.0571 0.0571
Echinococcus multilocularis neurogenic locus protein delta 0.0327 0.066 0.066
Toxoplasma gondii AGC kinase 0.0565 0.1422 0.1399
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0159 0.012 0.012
Trichomonas vaginalis CAMK family protein kinase 0.0155 0.0109 0.0276
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0298 0.0566 0.0566
Echinococcus multilocularis mitogen activated protein kinase 14 0.0316 0.0624 0.0624
Brugia malayi intracellular kinase 0.0255 0.043 0.043
Brugia malayi Stress-activated protein kinase jnk-1 0.0524 0.1293 0.1293
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.1122 0.3211 1
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0162 0.013 0.013
Schistosoma mansoni rap gtpase-activating protein 0.0222 0.0322 0.0322
Schistosoma mansoni serine/threonine protein kinase 0.0147 0.0083 0.0083
Onchocerca volvulus 0.0151 0.0096 0.036
Trichomonas vaginalis CMGC family protein kinase 0.0166 0.0144 0.0387
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0298 0.0566 0.1711
Brugia malayi Cyclin, N-terminal domain containing protein 0.0875 0.2418 0.2418
Brugia malayi Protein kinase domain containing protein 0.0129 0.0026 0.0026
Onchocerca volvulus 0.0151 0.0096 0.036
Echinococcus multilocularis neurogenic locus notch protein 0.0327 0.066 0.066
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0327 0.066 0.066
Brugia malayi pregnancy-associated plasma protein-A 0.0604 0.1549 0.1549
Echinococcus granulosus tyrosine protein kinase 0.0303 0.0582 0.0582
Echinococcus granulosus Protein kinase C brain isozyme 0.0483 0.1162 0.1162
Echinococcus granulosus tyrosine protein kinase Fyn 0.0302 0.058 0.058
Brugia malayi Protein kinase domain containing protein 0.0226 0.0337 0.0337
Trypanosoma cruzi hypothetical protein, conserved 0.0298 0.0566 0.0541
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0466 0.1106 0.1106
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0319 0.0635 0.0635
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0161 0.0127 0.01
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0243 0.0389 0.0389
Trichomonas vaginalis STE family protein kinase 0.0171 0.0159 0.0432
Brugia malayi Cam kinase protein 1 0.02 0.0253 0.0253
Schistosoma mansoni neuroglian 0.035 0.0734 0.0734
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0332 0.0676 0.0676
Schistosoma mansoni serine/threonine protein kinase 0.0155 0.0109 0.0109
Onchocerca volvulus 0.0178 0.0182 0.074
Brugia malayi casein kinase I 0.0216 0.0303 0.0303
Loa Loa (eye worm) hypothetical protein 0.0604 0.1549 0.1549
Schistosoma mansoni disulfide oxidoreductase 0.0298 0.0566 0.0566
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0432 0.0996 0.0996
Loa Loa (eye worm) hypothetical protein 0.0181 0.0191 0.0191
Trichomonas vaginalis CMGC family protein kinase 0.0236 0.0367 0.1086
Echinococcus granulosus neurogenic locus notch protein 4 0.0327 0.066 0.066
Schistosoma mansoni serine/threonine protein kinase 0.0305 0.0589 0.0589
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0224 0.033 0.0304
Schistosoma mansoni septate junction protein 0.0181 0.0191 0.0191
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0236 0.0367 0.0341
Onchocerca volvulus 0.0604 0.1549 0.6748
Brugia malayi Immunoglobulin I-set domain containing protein 0.0181 0.0191 0.0191
Brugia malayi Egg laying defective protein 4 0.0167 0.0145 0.0145
Trichomonas vaginalis AGC family protein kinase 0.034 0.0701 0.2131
Trypanosoma brucei protein kinase, putative 0.0183 0.0197 0.017
Toxoplasma gondii aurora kinase 0.0233 0.0358 0.0332
Brugia malayi Immunoglobulin I-set domain containing protein 0.0511 0.1249 0.1249
Echinococcus multilocularis roundabout 2 0.0947 0.2649 0.2649
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0181 0.0191 0.0191
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0359 0.0764 0.0764
Trichomonas vaginalis AGC family protein kinase 0.058 0.147 0.4544
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0222 0.0322 0.0295
Loa Loa (eye worm) AGC/PKN protein kinase 0.0576 0.146 0.146
Onchocerca volvulus 0.0604 0.1549 0.6748
Leishmania major casein kinase II, putative 0.0199 0.0248 0.0222
Schistosoma mansoni hypothetical protein 0.0327 0.066 0.066
Loa Loa (eye worm) hypothetical protein 0.0327 0.066 0.066
Leishmania major trypanothione reductase 0.3238 1 1
Giardia lamblia Kinase, AGC PKA 0.0311 0.0608 0.1523
Trichomonas vaginalis glutamate synthase, putative 0.0298 0.0566 0.1711
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0233 0.0358 0.1386
Echinococcus multilocularis C type lectin domian containing protein 0.0604 0.1549 0.1549
Brugia malayi hypothetical protein 0.0129 0.0026 0.0026
Trypanosoma cruzi casein kinase, putative 0.0216 0.0303 0.0276
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0302 0.058 0.058
Plasmodium falciparum calcium-dependent protein kinase 4 0.02 0.0253 0.0226
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0524 0.1293 0.1293
Entamoeba histolytica protein kinase, putative 0.0319 0.0635 0.2522
Schistosoma mansoni protein kinase 0.0526 0.1297 0.1297
Trichomonas vaginalis AGC family protein kinase 0.027 0.0478 0.1432
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0298 0.0566 0.0566
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0298 0.0566 0.0566
Loa Loa (eye worm) TK/FER protein kinase 0.0129 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0327 0.066 0.066
Entamoeba histolytica protein kinase, putative 0.0143 0.0069 0.0198
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0236 0.0367 0.0341
Plasmodium falciparum calcium-dependent protein kinase 1 0.02 0.0253 0.0226
Brugia malayi Calcium binding EGF domain containing protein 0.0327 0.066 0.066
Onchocerca volvulus Slit protein homolog 0.0371 0.0801 0.3461
Loa Loa (eye worm) hypothetical protein 0.035 0.0734 0.0734
Brugia malayi EGF-like domain containing protein 0.0371 0.0801 0.0801
Brugia malayi Immunoglobulin I-set domain containing protein 0.0151 0.0096 0.0096
Schistosoma mansoni protein kinase 0.0304 0.0586 0.0586

Activities

Activity type Activity value Assay description Source Reference
IC50 (ADMET) = 224 uM Cytotoxicity against Homo sapiens (human) A549 cells after 72 hr by MTT assay ChEMBL. No reference
MIC (functional) = 2 ug ml-1 Antimycobacterial activity against Mycobacterium tuberculosis H37Rv after 21 days by broth dilution method ChEMBL. No reference
MIC (functional) = 16 ug ml-1 Antifungal activity against Saccharomyces cerevisiae after 18 hr by broth microdilution technique ChEMBL. No reference
MIC (functional) = 16 ug ml-1 Antibacterial activity against Escherichia coli after 18 hr by broth microdilution technique ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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