Detailed information for compound 1806088

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 437.308 | Formula: C18H17BrN2O4S
  • H donors: 1 H acceptors: 2 LogP: 3.6 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccc(c(c1)C(=O)NN1C(=O)CSC1c1ccccc1OC)Br
  • InChi: 1S/C18H17BrN2O4S/c1-24-11-7-8-14(19)13(9-11)17(23)20-21-16(22)10-26-18(21)12-5-3-4-6-15(12)25-2/h3-9,18H,10H2,1-2H3,(H,20,23)
  • InChiKey: XIXVWNFOHGPSQA-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi EGF-like domain containing protein 0.0357 0.0685 0.0676
Schistosoma mansoni serine/threonine protein kinase 0.1034 0.2672 0.2665
Entamoeba histolytica p21-activated kinase 0.0195 0.021 0.0958
Trypanosoma cruzi aurora B kinase, putative 0.0244 0.0354 0.0318
Trypanosoma brucei NADH dehydrogenase 0.0325 0.0592 0.0557
Toxoplasma gondii AGC kinase 0.0235 0.0329 0.0293
Schistosoma mansoni serine/threonine protein kinase 0.0251 0.0375 0.0365
Loa Loa (eye worm) hypothetical protein 0.0842 0.2109 0.2101
Entamoeba histolytica PH domain containing protein kinase, putative 0.0251 0.0375 0.1844
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0325 0.0592 0.0592
Trichomonas vaginalis CAMK family protein kinase 0.0162 0.0115 0.0262
Brugia malayi Immunoglobulin I-set domain containing protein 0.0164 0.0119 0.0108
Loa Loa (eye worm) hypothetical protein 0.0382 0.076 0.075
Echinococcus multilocularis rho associated protein kinase 0.0676 0.1623 0.1623
Brugia malayi Protein kinase domain containing protein 0.0291 0.0492 0.0482
Loa Loa (eye worm) hypothetical protein 0.0382 0.076 0.075
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0331 0.061 0.0575
Onchocerca volvulus 0.0676 0.1623 0.7275
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0325 0.0592 0.0582
Echinococcus multilocularis neurogenic locus notch protein 4 0.0357 0.0685 0.0685
Echinococcus granulosus Opioid binding protein:cell adhesion molecule 0.0164 0.0119 0.0119
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0646 0.1534 0.1525
Echinococcus granulosus serine:threonine kinase SAD 1 0.0162 0.0115 0.0115
Brugia malayi p70 ribosomal S6 kinase beta 0.0592 0.1376 0.1366
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.021 0.0254 0.0254
Onchocerca volvulus 0.0164 0.0119 0.0428
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0244 0.0353 0.0343
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.1028 0.2656 0.2656
Trichomonas vaginalis CMGC family protein kinase 0.0208 0.025 0.0683
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0378 0.0749 0.0739
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0325 0.0592 0.0557
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0378 0.0749 0.0749
Schistosoma mansoni vesicular amine transporter 0.0646 0.1534 0.1525
Entamoeba histolytica casein kinase, putative 0.0226 0.0302 0.1453
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0933 0.2377 0.2368
Trichomonas vaginalis glutathione reductase, putative 0.1224 0.3229 1
Loa Loa (eye worm) disorganized muscle protein 1 0.0164 0.0119 0.0108
Entamoeba histolytica protein kinase, putative 0.0137 0.004 0.0044
Leishmania major hypothetical protein, conserved 0.0325 0.0592 0.0557
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0164 0.0119 0.0108
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0154 0.009 0.0079
Schistosoma mansoni protein kinase 0.0903 0.2287 0.2279
Giardia lamblia Kinase, CMGC MAPK 0.0174 0.015 0.0035
Schistosoma mansoni protein kinase 0.0551 0.1256 0.1246
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0341 0.064 0.063
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0254 0.0385 0.0349
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0592 0.1376 0.1366
Echinococcus multilocularis protein tyrosine kinase 0.0591 0.1373 0.1373
Echinococcus granulosus down syndrome cell adhesion 0.0164 0.0119 0.0119
Trypanosoma brucei Casein kinase II 0.0208 0.025 0.0213
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0314 0.0559 0.0549
Trichomonas vaginalis STE family protein kinase 0.0176 0.0156 0.0388
Brugia malayi Protein kinase domain containing protein 0.0135 0.0035 0.0025
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0162 0.0115 0.0078
Loa Loa (eye worm) casein kinase 0.0375 0.0739 0.0729
Brugia malayi Immunoglobulin I-set domain containing protein 0.0197 0.0215 0.0205
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0155 0.0094 0.0083
Echinococcus granulosus dual specificity 0.0289 0.0487 0.0487
Echinococcus granulosus NCK adaptor protein 0.0127 0.0011 0.0011
Brugia malayi Immunoglobulin I-set domain containing protein 0.0164 0.0119 0.0108
Loa Loa (eye worm) hypothetical protein 0.0135 0.0035 0.0025
Schistosoma mansoni septate junction protein 0.036 0.0694 0.0684
Echinococcus granulosus hemicentin 1 0.036 0.0694 0.0694
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0155 0.0094 0.0083
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0169 0.0133 0.0096
Schistosoma mansoni titin 0.0251 0.0375 0.0365
Echinococcus granulosus insulin receptor 0.062 0.1459 0.1459
Toxoplasma gondii AGC kinase 0.0592 0.1376 0.1344
Trypanosoma brucei hypothetical protein, conserved 0.0325 0.0592 0.0557
Plasmodium vivax glycogen synthase kinase 3, putative 0.0268 0.0424 0.0295
Schistosoma mansoni protein kinase 0.0903 0.2287 0.2279
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.051 0.1134 0.1125
Echinococcus multilocularis hemicentin 1 0.036 0.0694 0.0694
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0174 0.0149 0.0112
Brugia malayi Protein kinase domain containing protein 0.0403 0.0821 0.0812
Plasmodium falciparum thioredoxin reductase 0.1224 0.3229 0.3204
Plasmodium falciparum calcium-dependent protein kinase 3 0.021 0.0254 0.0218
Toxoplasma gondii AGC kinase 0.0235 0.0329 0.0293
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0325 0.0592 0.3008
Loa Loa (eye worm) TK/FER protein kinase 0.0135 0.0035 0.0025
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0254 0.0385 0.0349
Brugia malayi EGF-like domain containing protein 0.0357 0.0685 0.0676
Echinococcus granulosus activin receptor type 0.0136 0.0037 0.0037
Brugia malayi hypothetical protein 0.0135 0.0035 0.0025
Entamoeba histolytica hypothetical protein 0.0393 0.0793 0.409
Loa Loa (eye worm) hypothetical protein 0.0656 0.1563 0.1554
Schistosoma mansoni tyrosine kinase 0.0498 0.11 0.1091
Plasmodium falciparum apical sushi protein 0.0659 0.1572 0.154
Trichomonas vaginalis AGC family protein kinase 0.0235 0.0329 0.093
Brugia malayi glutamate synthase 0.0325 0.0592 0.0582
Trichomonas vaginalis CAMK family protein kinase 0.0162 0.0115 0.0262
Loa Loa (eye worm) hypothetical protein 0.0659 0.1572 0.1563
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.1224 0.3229 0.3222
Schistosoma mansoni serine/threonine protein kinase 0.0422 0.0876 0.0866
Plasmodium falciparum NIMA related kinase 1 0.0283 0.047 0.0434
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.1224 0.3229 0.3204
Loa Loa (eye worm) hypothetical protein 0.0384 0.0766 0.0756
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0451 0.0963 0.0953
Echinococcus granulosus roundabout 2 0.0378 0.0749 0.0749
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0325 0.0592 0.1464
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0268 0.0424 0.0414
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0173 0.0146 0.0109
Loa Loa (eye worm) hypothetical protein 0.0196 0.0214 0.0203
Trichomonas vaginalis STE family protein kinase 0.0179 0.0164 0.0414
Entamoeba histolytica PH domain containing protein kinase, putative 0.0251 0.0375 0.1844
Echinococcus multilocularis expressed conserved protein 0.0174 0.0149 0.0149
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0763 0.1877 0.1869
Brugia malayi SRC-1 0.0316 0.0565 0.0555
Schistosoma mansoni tyrosine kinase 0.0427 0.0891 0.0882
Echinococcus granulosus casein kinase I alpha 0.0226 0.0302 0.0302
Echinococcus granulosus basement membrane specific heparan sulfate 0.0196 0.0214 0.0214
Echinococcus multilocularis calcium dependent protein kinase 0.0141 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.0224 0.0295 0.0284
Brugia malayi Protein kinase domain containing protein 0.0341 0.064 0.063
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0325 0.0592 0.1752
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0341 0.064 0.064
Plasmodium vivax thioredoxin reductase, putative 0.3531 1 1
Trichomonas vaginalis apoptosis inducing factor, putative 0.0325 0.0592 0.1752
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0903 0.2287 0.2287
Loa Loa (eye worm) hypothetical protein 0.096 0.2455 0.2447
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0319 0.0574 0.0563
Echinococcus multilocularis dual specificity 0.0254 0.0385 0.0385
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0232 0.0321 0.0321
Echinococcus granulosus neuroglian 0.0378 0.0749 0.0749
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0262 0.0408 0.0398
Onchocerca volvulus 0.0133 0.0029 0.0021
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0235 0.0329 0.0198
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.021 0.0254 0.0218
Onchocerca volvulus Serine\/threonine kinase homolog 0.0341 0.064 0.2801
Onchocerca volvulus Slit protein homolog 0.0403 0.082 0.3621
Echinococcus granulosus leucine rich repeats and immunoglobulin 0.0164 0.0121 0.0121
Echinococcus granulosus cGMP dependent protein kinase 0.0174 0.0149 0.0149
Giardia lamblia Kinase, CMGC CDK 0.0247 0.0364 0.0728
Schistosoma mansoni laminin gamma-3 chain 0.0357 0.0685 0.0676
Plasmodium falciparum glycogen synthase kinase 3 0.0268 0.0424 0.0388
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0325 0.0592 0.1752
Leishmania major protein kinase, putative 0.032 0.0577 0.0541
Brugia malayi Immunoglobulin I-set domain containing protein 0.036 0.0694 0.0684
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0316 0.0565 0.0565
Plasmodium vivax ferrodoxin reductase, putative 0.0325 0.0592 0.0465
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0301 0.0523 0.0523
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0162 0.0115 0.0078
Echinococcus multilocularis epidermal growth factor receptor 0.0498 0.11 0.11
Loa Loa (eye worm) hypothetical protein 0.0357 0.0685 0.0676
Schistosoma mansoni tyrosine kinase 0.0376 0.0742 0.0732
Plasmodium falciparum serine/threonine protein kinase, putative 0.0244 0.0354 0.0318
Trichomonas vaginalis AGC family protein kinase 0.0356 0.0683 0.2038
Schistosoma mansoni cell adhesion molecule 0.036 0.0694 0.0684
Echinococcus granulosus serine:threonine protein kinase N2 0.0604 0.1412 0.1412
Echinococcus multilocularis neural cadherin 0.0357 0.0686 0.0686
Brugia malayi EGF-like domain containing protein 0.0357 0.0685 0.0676
Loa Loa (eye worm) hypothetical protein 0.0196 0.0214 0.0203
Trichomonas vaginalis CAMK family protein kinase 0.0263 0.041 0.1184
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.1224 0.3229 1
Brugia malayi hypothetical protein 0.0659 0.1572 0.1563
Trichomonas vaginalis CAMK family protein kinase 0.0162 0.0115 0.0262
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0174 0.015 0.0113
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.1224 0.3229 0.3229
Loa Loa (eye worm) SRC-1 0.0316 0.0565 0.0555
Schistosoma mansoni glutamate synthase 0.0325 0.0592 0.0582
Schistosoma mansoni serine/threonine protein kinase 0.0262 0.0408 0.0398
Brugia malayi Cam kinase protein 1 0.021 0.0254 0.0244
Echinococcus multilocularis mitogen activated protein kinase 14 0.0331 0.061 0.061
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0179 0.0164 0.0164
Loa Loa (eye worm) hypothetical protein 0.1006 0.2589 0.2582
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0174 0.015 0.0113
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0378 0.0749 0.0749
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0232 0.0321 0.0285
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0235 0.0329 0.0329
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0459 0.0986 0.0986
Brugia malayi Muscle positioning protein 4 0.0357 0.0685 0.0676
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0356 0.0683 0.0673
Schistosoma mansoni serine/threonine protein kinase 0.0174 0.015 0.0139
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0331 0.061 0.0575
Entamoeba histolytica protein kinase domain containing protein 0.0136 0.0037 0.0031
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0176 0.0156 0.0666
Brugia malayi EGF-like domain containing protein 0.0357 0.0685 0.0676
Giardia lamblia Kinase, AGC AKT 0.0244 0.0353 0.0693
Schistosoma mansoni hypothetical protein 0.0164 0.0119 0.0108
Schistosoma mansoni ste20-related kinase 0.0427 0.0891 0.0881
Echinococcus multilocularis dual specificity 0.0289 0.0487 0.0487
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.021 0.0254 0.0244
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0341 0.0638 0.0628
Trichomonas vaginalis AGC family protein kinase 0.0343 0.0645 0.1918
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0331 0.061 0.0575
Echinococcus multilocularis 0.0198 0.0219 0.0219
Schistosoma mansoni cell adhesion molecule 0.0378 0.0749 0.0739
Echinococcus granulosus Protein kinase C brain isozyme 0.0507 0.1126 0.1126
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0325 0.0592 0.0465
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0733 0.1791 0.1782
Entamoeba histolytica protein kinase , putative 0.0244 0.0354 0.1734
Echinococcus granulosus ephrin type A receptor 4 A 0.02 0.0227 0.0227
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0247 0.0364 0.0354
Trypanosoma brucei cdc2-related kinase 3 0.0247 0.0364 0.0328
Trichomonas vaginalis CAMK family protein kinase 0.021 0.0254 0.0697
Loa Loa (eye worm) hypothetical protein 0.0164 0.0119 0.0108
Echinococcus granulosus epidermal growth factor receptor 0.0498 0.11 0.11
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0232 0.0321 0.031
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0169 0.0133 0.0096
Loa Loa (eye worm) immunoglobulin domain-containing protein 0.0196 0.0214 0.0203
Loa Loa (eye worm) hypothetical protein 0.0164 0.0119 0.0108
Loa Loa (eye worm) hypothetical protein 0.0646 0.1535 0.1526
Loa Loa (eye worm) hypothetical protein 0.0325 0.0592 0.0582
Brugia malayi phosphoinositide-dependent protein kinase I 0.017 0.0136 0.0126
Echinococcus multilocularis serine:threonine protein kinase 0.0237 0.0335 0.0335
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.051 0.1134 0.1134
Echinococcus granulosus tyrosine protein kinase Btk29A 0.047 0.1018 0.1018
Schistosoma mansoni protein kinase 0.0208 0.025 0.0239
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0325 0.0592 0.1752
Loa Loa (eye worm) hypothetical protein 0.0357 0.0685 0.0676
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0562 0.1288 0.1288
Leishmania major protein kinase A catalytic subunit 0.0235 0.0329 0.0293
Loa Loa (eye worm) LAD-2 short isoform 0.0196 0.0214 0.0203
Echinococcus granulosus expressed protein 0.0173 0.0146 0.0146
Entamoeba histolytica protein kinase, putative 0.0179 0.0164 0.0711
Echinococcus multilocularis ephrin type A receptor 4 A 0.02 0.0227 0.0227
Loa Loa (eye worm) hypothetical protein 0.0235 0.0329 0.0318
Brugia malayi Immunoglobulin I-set domain containing protein 0.0182 0.0174 0.0163
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.032 0.0577 0.0541
Echinococcus multilocularis casein kinase i 0.0226 0.0302 0.0302
Schistosoma mansoni tyrosine kinase 0.0714 0.1733 0.1724
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0239 0.0341 0.0341
Giardia lamblia Kinase, CMGC GSK 0.0268 0.0424 0.0922
Brugia malayi cell division control protein 2 homolog 0.0247 0.0364 0.0354
Loa Loa (eye worm) hypothetical protein 0.0169 0.0136 0.0125
Schistosoma mansoni protein kinase 0.0226 0.0302 0.0292
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0268 0.0424 0.0424
Leishmania major NADH dehydrogenase, putative 0.0325 0.0592 0.0557
Brugia malayi ephrin receptor 1 precursor 0.013 0.002 0.0009
Trichomonas vaginalis AGC family protein kinase 0.0608 0.1422 0.4348
Loa Loa (eye worm) hypothetical protein 0.0196 0.0214 0.0203
Loa Loa (eye worm) hypothetical protein 0.0196 0.0214 0.0203
Schistosoma mansoni hypothetical protein 0.0357 0.0685 0.0676
Trichomonas vaginalis CMGC family protein kinase 0.0187 0.0187 0.0486
Loa Loa (eye worm) hypothetical protein 0.0248 0.0367 0.0357
Schistosoma mansoni hypothetical protein 0.0357 0.0685 0.0676
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0325 0.0592 0.0592
Entamoeba histolytica thioredoxin reductase, putative 0.0325 0.0592 0.3008
Schistosoma mansoni protein kinase 0.0459 0.0986 0.0977
Echinococcus granulosus tyrosine kinase 0.0257 0.0393 0.0393
Loa Loa (eye worm) hypothetical protein 0.0378 0.0749 0.0739
Loa Loa (eye worm) hypothetical protein 0.0164 0.0119 0.0108
Brugia malayi Immunoglobulin I-set domain containing protein 0.0378 0.0749 0.0739
Plasmodium falciparum thioredoxin reductase 0.3531 1 1
Giardia lamblia Kinase, AGC PKA 0.0235 0.0329 0.0613
Loa Loa (eye worm) hypothetical protein 0.0357 0.0685 0.0676
Trichomonas vaginalis CMGC family protein kinase 0.0289 0.0487 0.1425
Trichomonas vaginalis CMGC family protein kinase 0.0187 0.0187 0.0486
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0325 0.0592 0.0557
Entamoeba histolytica protein kinase, putative 0.0254 0.0385 0.1898
Loa Loa (eye worm) hypothetical protein 0.0164 0.0119 0.0108
Echinococcus multilocularis cyclin dependent kinase 19 0.1034 0.2672 0.2672
Echinococcus granulosus rho-associated protein kinase 1 0.0676 0.1623 0.1623
Loa Loa (eye worm) hypothetical protein 0.036 0.0694 0.0684
Plasmodium falciparum calcium-dependent protein kinase 2 0.021 0.0254 0.0218
Schistosoma mansoni hypothetical protein 0.0232 0.0321 0.031
Schistosoma mansoni hypothetical protein 0.0196 0.0214 0.0203
Brugia malayi Delta serrate ligand family protein 0.0357 0.0685 0.0676
Echinococcus granulosus delta-like protein 1 0.0357 0.0685 0.0685
Plasmodium vivax casein kinase 1, putative 0.0226 0.0302 0.0171
Brugia malayi intracellular kinase 0.0268 0.0424 0.0414
Echinococcus granulosus STE20 serine:threonine protein kinase 0.1028 0.2656 0.2656
Trypanosoma cruzi Protein kinase B 0.0342 0.0641 0.0606
Loa Loa (eye worm) AGC/AKT protein kinase 0.0608 0.1422 0.1413
Toxoplasma gondii casein kinase I 0.0226 0.0302 0.0266
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.051 0.1134 0.1134
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0254 0.0385 0.0375
Loa Loa (eye worm) TK/ROR protein kinase 0.0231 0.0316 0.0306
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0259 0.04 0.0364
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0366 0.0712 0.0702
Brugia malayi SH2 domain containing protein 0.0449 0.0957 0.0947
Trichomonas vaginalis CMGC family protein kinase 0.0247 0.0364 0.104
Loa Loa (eye worm) protein kinase domain-containing protein 0.0444 0.094 0.0931
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0173 0.0146 0.0109
Brugia malayi P38 map kinase family protein 2 0.0331 0.061 0.06
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0325 0.0592 0.0557
Loa Loa (eye worm) hypothetical protein 0.0659 0.1572 0.1563
Brugia malayi Immunoglobulin I-set domain containing protein 0.0164 0.0119 0.0108
Entamoeba histolytica protein kinase, putative 0.0268 0.0424 0.2109
Schistosoma mansoni notch 0.0357 0.0685 0.0676
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0174 0.015 0.0113
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.017 0.0136 0.0136
Schistosoma mansoni c4b-binding protein beta chain 0.0659 0.1572 0.1563
Schistosoma mansoni notch 0.0357 0.0685 0.0676
Schistosoma mansoni hypothetical protein 0.0212 0.026 0.025
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0262 0.0408 0.0408
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0325 0.0592 0.1752
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0325 0.0592 0.0557
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.021 0.0254 0.0254
Trichomonas vaginalis CAMK family protein kinase 0.0562 0.1288 0.3931
Schistosoma mansoni serine/threonine protein kinase 0.0604 0.1412 0.1403
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0447 0.0951 0.0941
Echinococcus multilocularis tyrosine protein kinase 0.0315 0.0564 0.0564
Schistosoma mansoni protein kinase 0.0179 0.0164 0.0153
Echinococcus multilocularis serine:threonine protein kinase 38 0.0335 0.0621 0.0621
Brugia malayi protein kinase C3,putative 0.0328 0.0601 0.0591
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.021 0.0254 0.0254
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0449 0.0957 0.0957
Brugia malayi EGF-like domain containing protein 0.0403 0.082 0.0811
Loa Loa (eye worm) TK/FER protein kinase 0.0135 0.0035 0.0025
Echinococcus multilocularis neurogenic locus protein delta 0.0357 0.0685 0.0685
Echinococcus multilocularis roundabout 2 0.1024 0.2644 0.2644
Loa Loa (eye worm) TK/FER protein kinase 0.0135 0.0035 0.0025
Schistosoma mansoni serine/threonine protein kinase 0.082 0.2045 0.2036
Schistosoma mansoni protein kinase 0.0763 0.1877 0.1869
Loa Loa (eye worm) TK/EPH protein kinase 0.0237 0.0334 0.0323
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0325 0.0592 0.0592
Onchocerca volvulus 0.0608 0.1422 0.6358
Echinococcus granulosus Down syndrome cell adhesion molecule 0.0215 0.0269 0.0269
Echinococcus multilocularis casein kinase ii subunit alpha 0.0208 0.025 0.025
Echinococcus multilocularis death associated protein kinase 1 0.0913 0.2317 0.2317
Loa Loa (eye worm) TK protein kinase 0.0315 0.0564 0.0554
Brugia malayi Prion-like- 0.0164 0.0119 0.0108
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0182 0.0174 0.0163
Echinococcus granulosus tyrosine protein kinase Blk 0.0257 0.0393 0.0393
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0196 0.0214 0.0203
Brugia malayi Cyclin, N-terminal domain containing protein 0.0758 0.1862 0.1853
Echinococcus granulosus protein jagged 2 0.0357 0.0685 0.0685
Onchocerca volvulus Peroxidasin homolog 0.0164 0.0121 0.0436
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.021 0.0254 0.0218
Plasmodium vivax protein kinase Crk2 0.0247 0.0364 0.0234
Loa Loa (eye worm) hypothetical protein 0.0164 0.0119 0.0108
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0331 0.061 0.06
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0164 0.0119 0.0108
Trichomonas vaginalis CMGC family protein kinase 0.0174 0.015 0.037
Trichomonas vaginalis CAMK family protein kinase 0.0263 0.041 0.1184
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1224 0.3229 0.3204
Onchocerca volvulus 0.0659 0.1572 0.704
Echinococcus granulosus Immunoglobulin 0.0196 0.0214 0.0214
Mycobacterium ulcerans flavoprotein disulfide reductase 0.1224 0.3229 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0182 0.0174 0.0163
Trichomonas vaginalis CAMK family protein kinase 0.0162 0.0115 0.0262
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0639 0.1514 0.1514
Loa Loa (eye worm) hypothetical protein 0.0659 0.1572 0.1563
Loa Loa (eye worm) hypothetical protein 0.0289 0.0486 0.0476
Schistosoma mansoni cell adhesion molecule 0.0196 0.0214 0.0203
Echinococcus multilocularis roundabout 2 0.0378 0.0749 0.0749
Loa Loa (eye worm) TK/FER protein kinase 0.0135 0.0035 0.0025
Loa Loa (eye worm) AGC/PKA protein kinase 0.0235 0.0329 0.0318
Schistosoma mansoni serine/threonine protein kinase 0.051 0.1134 0.1125
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0325 0.0592 0.3008
Echinococcus multilocularis casein kinase I delta 0.0226 0.0302 0.0302
Onchocerca volvulus 0.0135 0.0035 0.0048
Echinococcus granulosus cGMP dependent protein kinase 1 0.0174 0.0149 0.0149
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.1224 0.3229 0.3229
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.1224 0.3229 0.3204
Onchocerca volvulus 0.0135 0.0035 0.0048
Loa Loa (eye worm) hypothetical protein 0.0659 0.1572 0.1563
Loa Loa (eye worm) hypothetical protein 0.0646 0.1534 0.1525
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0192 0.0201 0.0201
Echinococcus multilocularis c Jun NH2 terminal kinase 0.055 0.1252 0.1252
Giardia lamblia Kinase, PLK 0.0562 0.1288 0.372
Echinococcus granulosus titin 0.0251 0.0375 0.0375
Schistosoma mansoni slit 0.0357 0.0687 0.0677
Brugia malayi SH2 domain containing protein 0.0135 0.0035 0.0025
Schistosoma mansoni tyrosine kinase 0.0498 0.11 0.1091
Brugia malayi RhoGAP domain containing protein 0.0155 0.0094 0.0083
Echinococcus multilocularis tyrosine protein kinase HCK 0.0189 0.0193 0.0193
Loa Loa (eye worm) hypothetical protein 0.0357 0.0685 0.0676
Echinococcus granulosus protein tyrosine kinase 0.0591 0.1373 0.1373
Loa Loa (eye worm) Notch2 0.0357 0.0685 0.0676
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.1224 0.3229 0.3204
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0235 0.0329 0.0318
Brugia malayi Protein kinase domain containing protein 0.0608 0.1422 0.1413
Schistosoma mansoni hypothetical protein 0.0325 0.0592 0.0582
Loa Loa (eye worm) cyclin domain-containing protein 0.0758 0.1862 0.1853
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0235 0.0329 0.0293
Schistosoma mansoni serine/threonine protein kinase 0.0733 0.1791 0.1782
Trichomonas vaginalis CAMK family protein kinase 0.0562 0.1288 0.3931
Echinococcus granulosus casein kinase I alpha 0.0226 0.0302 0.0302
Loa Loa (eye worm) hypothetical protein 0.0659 0.1572 0.1563
Entamoeba histolytica protein kinase 2, putative 0.0326 0.0595 0.3025
Leishmania major protein kinase, putative 0.0244 0.0354 0.0318
Schistosoma mansoni sulfide quinone reductase 0.0325 0.0592 0.0582
Echinococcus granulosus serine:threonine protein kinase 0.0237 0.0335 0.0335
Echinococcus granulosus tyrosine protein kinase otk 0.036 0.0694 0.0694
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.1224 0.3229 0.3204
Brugia malayi Immunoglobulin I-set domain containing protein 0.0164 0.0119 0.0108
Loa Loa (eye worm) hypothetical protein 0.036 0.0694 0.0684
Brugia malayi Immunoglobulin I-set domain containing protein 0.0164 0.0119 0.0108
Onchocerca volvulus 0.0659 0.1572 0.704
Giardia lamblia Kinase, STE STE20 0.0179 0.0164 0.008
Brugia malayi pregnancy-associated plasma protein-A 0.0659 0.1572 0.1563
Echinococcus granulosus cyclin dependent kinase 1 0.0247 0.0364 0.0364
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.017 0.0136 0.0136
Schistosoma mansoni hypothetical protein 0.0357 0.0686 0.0676
Echinococcus multilocularis CDC7 cell division cycle 7 0.0187 0.0187 0.0187
Brugia malayi Immunoglobulin I-set domain containing protein 0.0215 0.0269 0.0258
Echinococcus multilocularis leucine rich repeat containing protein 4 0.0196 0.0214 0.0214
Echinococcus granulosus tyrosine protein kinase Fyn 0.0316 0.0565 0.0565
Loa Loa (eye worm) hypothetical protein 0.0164 0.0119 0.0108
Schistosoma mansoni serine/threonine protein kinase 0.0418 0.0864 0.0854
Trypanosoma brucei protein kinase, putative 0.0268 0.0424 0.0388
Trypanosoma cruzi casein kinase, putative 0.0226 0.0302 0.0266
Echinococcus multilocularis tyrosine protein kinase Blk 0.0257 0.0393 0.0393
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0378 0.0749 0.0739
Echinococcus multilocularis protein jagged 1 0.0357 0.0685 0.0685
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0196 0.0214 0.0203
Echinococcus granulosus notch 0.0357 0.0685 0.0685
Schistosoma mansoni serine/threonine protein kinase 0.0191 0.02 0.0189
Schistosoma mansoni cell adhesion molecule 0.0182 0.0174 0.0163
Echinococcus multilocularis raf serine:threonine protein kinase 0.0154 0.0091 0.0091
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.1224 0.3229 0.3204
Trichomonas vaginalis CAMK family protein kinase 0.0562 0.1288 0.3931
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0489 0.1073 0.1073
Brugia malayi Immunoglobulin domain containing protein 0.0196 0.0214 0.0203
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0137 0.004 0.0044
Echinococcus multilocularis neurogenic locus protein delta 0.0357 0.0685 0.0685
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0244 0.0354 0.1734
Trypanosoma cruzi casein kinase, putative 0.0226 0.0302 0.0266
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0289 0.0487 0.0452
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0235 0.0329 0.0329
Trichomonas vaginalis glutamate synthase, putative 0.0325 0.0592 0.1752
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0208 0.025 0.0118
Schistosoma mansoni serine/threonine protein kinase 0.032 0.0577 0.0567
Entamoeba histolytica protein kinase, putative 0.017 0.0136 0.0562
Schistosoma mansoni cell adhesion molecule 0.0861 0.2164 0.2156
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0268 0.0424 0.0424
Loa Loa (eye worm) hypothetical protein 0.0659 0.1572 0.1563
Loa Loa (eye worm) hypothetical protein 0.1015 0.2619 0.2611
Echinococcus multilocularis peroxidasin 0.036 0.0696 0.0696
Echinococcus granulosus protein kinase c epsilon type 0.0424 0.0884 0.0884
Brugia malayi Protein kinase domain containing protein 0.0451 0.0963 0.0953
Onchocerca volvulus 0.0135 0.0035 0.0048
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0326 0.0595 0.0595
Schistosoma mansoni notch 0.0357 0.0685 0.0676
Brugia malayi Immunoglobulin I-set domain containing protein 0.036 0.0694 0.0684
Loa Loa (eye worm) animal heme peroxidase 0.0164 0.0119 0.0108
Brugia malayi Thioredoxin reductase 0.3531 1 1
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0174 0.015 0.0113
Loa Loa (eye worm) hypothetical protein 0.0164 0.0119 0.0108
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0562 0.1288 0.1256
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0176 0.0156 0.0119
Giardia lamblia Kinase, NEK 0.0283 0.047 0.107
Entamoeba histolytica cell division protein kinase 2, putative 0.0255 0.0388 0.1913
Brugia malayi Protein kinase domain containing protein 0.0129 0.0016 0.0006
Loa Loa (eye worm) AUR protein kinase 0.0244 0.0354 0.0344
Trichomonas vaginalis CMGC family protein kinase 0.0208 0.025 0.0683
Echinococcus multilocularis netrin receptor unc 5 0.0256 0.039 0.039
Loa Loa (eye worm) hypothetical protein 0.0357 0.0685 0.0676
Loa Loa (eye worm) AUR protein kinase 0.0244 0.0354 0.0344
Schistosoma mansoni hypothetical protein 0.0196 0.0214 0.0203
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0498 0.11 0.11
Brugia malayi Prion-like- 0.0164 0.0119 0.0108
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0418 0.0864 0.0854
Schistosoma mansoni notch 0.0357 0.0685 0.0676
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0179 0.0164 0.0164
Brugia malayi Peroxidasin 0.036 0.0696 0.0686
Brugia malayi EGF-like domain containing protein 0.0357 0.0685 0.0676
Schistosoma mansoni notch 0.0357 0.0685 0.0676
Schistosoma mansoni disulfide oxidoreductase 0.0325 0.0592 0.0582
Brugia malayi Protein kinase domain containing protein 0.0733 0.1791 0.1782
Onchocerca volvulus 0.0357 0.0685 0.3007
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0235 0.0329 0.0329
Onchocerca volvulus 0.0297 0.051 0.221
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0325 0.0592 0.0582
Schistosoma mansoni serine/threonine protein kinase 0.0235 0.0329 0.0318
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0164 0.0119 0.0119
Loa Loa (eye worm) hypothetical protein 0.0164 0.0119 0.0108
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.1224 0.3229 1
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0235 0.0329 0.0329
Echinococcus multilocularis aurora kinase A 0.0244 0.0354 0.0354
Entamoeba histolytica protein kinase domain containing protein 0.0208 0.025 0.1173
Toxoplasma gondii CMGC kinase, CK2 family 0.0208 0.025 0.0213
Echinococcus multilocularis tyrosine protein kinase Srms 0.0257 0.0393 0.0393
Giardia lamblia High cysteine protein 0.0357 0.0685 0.1768
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0335 0.0621 0.0621
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0325 0.0592 0.0557
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.1508 0.4064 0.4064
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0489 0.1073 0.1073
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0449 0.0957 0.0957
Echinococcus granulosus defective proboscis extension response 0.0646 0.1534 0.1534
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0179 0.0164 0.0164
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.1224 0.3229 0.3204
Trichomonas vaginalis glutamate synthase, putative 0.0325 0.0592 0.1752
Schistosoma mansoni hypothetical protein 0.0164 0.0119 0.0108
Loa Loa (eye worm) hypothetical protein 0.036 0.0694 0.0684
Onchocerca volvulus 0.0164 0.0119 0.0428
Entamoeba histolytica protein kinase, putative 0.0335 0.0621 0.3165
Entamoeba histolytica protein kinase, putative 0.0592 0.1376 0.7217
Brugia malayi Immunoglobulin I-set domain containing protein 0.0256 0.039 0.038
Echinococcus granulosus peroxidasin 0.036 0.0696 0.0696
Giardia lamblia Kinase, STE STE20 0.0176 0.0156 0.0053
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0763 0.1877 0.1877
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0171 0.0139 0.0006
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0235 0.0329 0.0329
Brugia malayi serine/threonine protein kinase 6 0.0244 0.0354 0.0344
Loa Loa (eye worm) pregnancy-associated plasma protein-E 0.0659 0.1572 0.1563
Echinococcus granulosus nephrin 0.0182 0.0174 0.0174
Echinococcus multilocularis myosin iiia 0.0176 0.0156 0.0156
Schistosoma mansoni serine/threonine protein kinase 0.032 0.0577 0.0567
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0733 0.1791 0.1791
Brugia malayi Hr1 repeat family protein 0.0604 0.1412 0.1403
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0326 0.0595 0.056
Schistosoma mansoni tyrosine kinase 0.0431 0.0903 0.0893
Brugia malayi Immunoglobulin I-set domain containing protein 0.0196 0.0214 0.0203
Trichomonas vaginalis CMGC family protein kinase 0.0289 0.0487 0.1425
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0289 0.0487 0.0452
Echinococcus multilocularis casein kinase I alpha 0.0226 0.0302 0.0302
Loa Loa (eye worm) hypothetical protein 0.0659 0.1572 0.1563
Echinococcus multilocularis mitogen activated protein kinase 3 0.0174 0.015 0.015
Schistosoma mansoni septate junction protein 0.0196 0.0214 0.0203
Echinococcus multilocularis neuroglian 0.081 0.2014 0.2014
Loa Loa (eye worm) hypothetical protein 0.0133 0.0029 0.0019
Giardia lamblia Kinase, AGC PKA 0.0326 0.0595 0.1475
Brugia malayi Doublecortin family protein 0.0314 0.0559 0.0549
Echinococcus granulosus epidermal growth factor receptor 0.0714 0.1733 0.1733
Giardia lamblia NADH oxidase lateral transfer candidate 0.1224 0.3229 1
Onchocerca volvulus 0.0226 0.0302 0.1262
Loa Loa (eye worm) hypothetical protein 0.0376 0.0741 0.0731
Toxoplasma gondii rhoptry neck protein RON9 0.0659 0.1572 0.154
Echinococcus granulosus thioredoxin glutathione reductase 0.3531 1 1
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0562 0.1288 0.1288
Loa Loa (eye worm) hypothetical protein 0.0357 0.0685 0.0676
Plasmodium falciparum protein kinase 5 0.0247 0.0364 0.0328
Echinococcus granulosus titin 0.0164 0.0119 0.0119
Schistosoma mansoni serine/threonine protein kinase 0.0676 0.1623 0.1614
Schistosoma mansoni hypothetical protein 0.0212 0.026 0.025
Loa Loa (eye worm) hypothetical protein 0.021 0.0254 0.0244
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0244 0.0354 0.0354
Brugia malayi Immunoglobulin I-set domain containing protein 0.036 0.0694 0.0684
Toxoplasma gondii histone kinase SNF1, putative 0.0162 0.0115 0.0078
Echinococcus multilocularis dual specificity 0.0289 0.0487 0.0487
Schistosoma mansoni serine/threonine protein kinase 0.0187 0.0187 0.0176
Trichomonas vaginalis CMGC family protein kinase 0.0174 0.015 0.037
Echinococcus granulosus dual specificity 0.0289 0.0487 0.0487
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0449 0.0957 0.0957
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.1224 0.3229 1
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0226 0.0302 0.0292
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0176 0.0156 0.0119
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0733 0.1791 0.1791
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.1224 0.3229 0.3204
Echinococcus multilocularis fat cadherin tumor suppressor 0.0357 0.0686 0.0686
Schistosoma mansoni serine/threonine protein kinase 0.0162 0.0115 0.0105
Echinococcus multilocularis roundabout 2 0.0378 0.0749 0.0749
Brugia malayi Protein kinase domain containing protein 0.062 0.1459 0.145
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0257 0.0393 0.0393
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0196 0.0214 0.0214
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0325 0.0592 0.0592
Trichomonas vaginalis CAMK family protein kinase 0.0162 0.0115 0.0262
Schistosoma mansoni subfamily M23B non-peptidase homologue (M23 family) 0.0164 0.0119 0.0108
Entamoeba histolytica protein kinase, putative 0.0608 0.1422 0.7465
Brugia malayi casein kinase 1, delta 0.0226 0.0302 0.0292
Trichomonas vaginalis AGC family protein kinase 0.0178 0.016 0.0402
Entamoeba histolytica protein kinase, putative 0.0608 0.1422 0.7465
Schistosoma mansoni protein kinase 0.0459 0.0986 0.0977
Schistosoma mansoni serine/threonine protein kinase 0.0281 0.0462 0.0452
Leishmania major protein kinase, putative 0.021 0.0254 0.0218
Brugia malayi Protein kinase domain containing protein 0.0933 0.2377 0.2368
Brugia malayi Cadherin domain containing protein 0.0357 0.0686 0.0676
Echinococcus multilocularis serine:threonine protein kinase N2 0.0604 0.1412 0.1412
Loa Loa (eye worm) hypothetical protein 0.0232 0.0321 0.031
Schistosoma mansoni atypical protein kinase C 0.0607 0.1419 0.141
Echinococcus multilocularis casein kinase I delta 0.0226 0.0302 0.0302
Plasmodium falciparum cGMP-dependent protein kinase 0.0174 0.0149 0.0112
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0462 0.0995 0.0985
Echinococcus multilocularis nervana 2 0.0257 0.0393 0.0393
Brugia malayi MAP kinase sur-1 0.0174 0.015 0.0139
Schistosoma mansoni protein kinase 0.0401 0.0816 0.0806
Trypanosoma brucei protein kinase, putative 0.0182 0.0174 0.0137
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0244 0.0354 0.0354
Echinococcus granulosus cyclin dependent kinase 19 0.1034 0.2672 0.2672
Echinococcus multilocularis NCK adaptor protein 0.0129 0.0017 0.0017
Echinococcus multilocularis down syndrome cell adhesion 0.0164 0.0119 0.0119
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0235 0.0329 0.0293
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.021 0.0254 0.0244
Loa Loa (eye worm) hypothetical protein 0.0212 0.026 0.025
Loa Loa (eye worm) projectin 0.0182 0.0174 0.0163
Entamoeba histolytica protein kinase domain containing protein 0.0254 0.0385 0.1898
Entamoeba histolytica protein kinase, putative 0.0173 0.0146 0.0615
Giardia lamblia Kinase, CK1 Casein kinase 0.0226 0.0302 0.0527
Schistosoma mansoni vam6/vps39 related 0.0232 0.0321 0.031
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0174 0.015 0.0113
Schistosoma mansoni serine/threonine protein kinase 0.0174 0.0149 0.0138
Leishmania major protein kinase, putative 0.032 0.0577 0.0541
Onchocerca volvulus 0.0164 0.0119 0.0428
Trichomonas vaginalis CMGC family protein kinase 0.0268 0.0424 0.1228
Trichomonas vaginalis CMGC family protein kinase 0.0289 0.0487 0.1425
Echinococcus multilocularis titin 0.0251 0.0375 0.0375
Brugia malayi Immunoglobulin I-set domain containing protein 0.0196 0.0214 0.0203
Trichomonas vaginalis CMGC family protein kinase 0.0289 0.0487 0.1425
Schistosoma mansoni glutamate synthase 0.0325 0.0592 0.0582
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0341 0.064 0.064
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0268 0.0424 0.0414
Loa Loa (eye worm) hypothetical protein 0.0623 0.1468 0.1459
Schistosoma mansoni titin 0.036 0.0694 0.0684
Onchocerca volvulus Tyrosine kinase homolog 0.088 0.2222 1
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0424 0.0884 0.0874
Onchocerca volvulus 0.0187 0.0187 0.0737
Echinococcus multilocularis cyclin 0.0758 0.1862 0.1862
Loa Loa (eye worm) AGC/PKA protein kinase 0.0235 0.0329 0.0318
Echinococcus multilocularis Immunoglobulin 0.0196 0.0214 0.0214
Loa Loa (eye worm) hypothetical protein 0.0216 0.0271 0.0261
Schistosoma mansoni protein kinase 0.0319 0.0574 0.0563
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0656 0.1563 0.1554
Echinococcus multilocularis leucine rich repeats and immunoglobulin 0.0164 0.0121 0.0121
Loa Loa (eye worm) CMGC/CLK protein kinase 0.032 0.0577 0.0567
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.1224 0.3229 0.3204
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0331 0.061 0.0575
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0316 0.0565 0.0565
Onchocerca volvulus 0.0659 0.1572 0.704
Schistosoma mansoni serine/threonine protein kinase 0.0449 0.0957 0.0948
Echinococcus granulosus neurogenic locus notch protein 0.0357 0.0685 0.0685
Onchocerca volvulus 0.0289 0.0486 0.2097
Plasmodium vivax calcium-dependent protein kinase, putative 0.021 0.0254 0.0123
Schistosoma mansoni serine/threonine protein kinase 0.021 0.0254 0.0244
Schistosoma mansoni roundabout 0.036 0.0694 0.0684
Echinococcus multilocularis Immunoglobulin 0.0646 0.1534 0.1534
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0462 0.0995 0.0995
Giardia lamblia Kinase, CMGC GSK 0.0268 0.0424 0.0922
Echinococcus granulosus raf serine:threonine protein kinase 0.0154 0.0091 0.0091
Entamoeba histolytica protein kinase domain containing protein 0.0289 0.0487 0.2446
Schistosoma mansoni serine/threonine protein kinase 0.0173 0.0146 0.0136
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0449 0.0957 0.0957
Brugia malayi Immunoglobulin I-set domain containing protein 0.0164 0.0119 0.0108
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0226 0.0302 0.0266
Echinococcus multilocularis nervana 2 0.0257 0.0393 0.0393
Trichomonas vaginalis AGC family protein kinase 0.0608 0.1422 0.4348
Echinococcus granulosus neuroglian 0.081 0.2014 0.2014
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0325 0.0592 0.1752
Onchocerca volvulus 0.0187 0.0187 0.0737
Echinococcus granulosus cGMP dependent protein kinase 1 0.0174 0.0149 0.0149
Echinococcus multilocularis Immunoglobulin 0.0196 0.0214 0.0214
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0235 0.0329 0.0293
Giardia lamblia Kinase, CMGC CLK 0.032 0.0577 0.1416
Onchocerca volvulus 0.0659 0.1572 0.704
Schistosoma mansoni tyrosine kinase 0.062 0.1459 0.145
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.047 0.1018 0.1018
Schistosoma mansoni peroxidasin 0.0197 0.0215 0.0205
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0235 0.0329 0.0293
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0325 0.0592 0.0557
Onchocerca volvulus Netrin receptor homolog 0.0224 0.0295 0.1232
Mycobacterium tuberculosis Probable oxidoreductase 0.1224 0.3229 0.2803
Schistosoma mansoni serine/threonine-protein kinase 0.0342 0.0641 0.0631
Trichomonas vaginalis CMGC family protein kinase 0.0208 0.025 0.0683
Loa Loa (eye worm) hypothetical protein 0.0237 0.0335 0.0325
Echinococcus multilocularis tyrosine protein kinase shark 0.0356 0.0684 0.0684
Echinococcus granulosus neural cadherin 0.0357 0.0686 0.0686
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0325 0.0592 0.0592
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0656 0.1563 0.1554
Brugia malayi Tyrosine-protein kinase abl-1 0.0194 0.0208 0.0197
Onchocerca volvulus 0.0357 0.0685 0.3007
Brugia malayi hypothetical protein 0.0665 0.1589 0.158
Echinococcus granulosus insulin growth factor binding 0.0164 0.0119 0.0119
Echinococcus granulosus netrin receptor unc 5 0.0256 0.039 0.039
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0325 0.0592 0.0557
Loa Loa (eye worm) TK/INSR protein kinase 0.062 0.1459 0.145
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0325 0.0592 0.1752
Trypanosoma brucei trypanothione reductase 0.3531 1 1
Brugia malayi protein kinase C II. 0.0424 0.0884 0.0874
Schistosoma mansoni tyrosine kinase 0.0431 0.0903 0.0893
Brugia malayi serine/threonine-protein kinase plk-2 0.0562 0.1288 0.1279
Brugia malayi hypothetical protein 0.0232 0.0321 0.031
Loa Loa (eye worm) hypothetical protein 0.0164 0.0119 0.0108
Trichomonas vaginalis CK1 family protein kinase 0.0226 0.0302 0.0846
Schistosoma mansoni glutamate synthase 0.0325 0.0592 0.0582
Brugia malayi hypothetical protein 0.0659 0.1572 0.1563
Entamoeba histolytica serine/threonine protein kinase, putative 0.0162 0.0115 0.045
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0325 0.0592 0.0557
Trypanosoma cruzi NADH dehydrogenase, putative 0.0325 0.0592 0.0557
Leishmania major protein kinase A catalytic subunit isoform 1 0.0235 0.0329 0.0293
Schistosoma mansoni serine/threonine protein kinase 0.0162 0.0115 0.0105
Echinococcus granulosus protein kinase c iota type 0.0594 0.1382 0.1382
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0903 0.2287 0.2287
Trichomonas vaginalis CAMK family protein kinase 0.0162 0.0115 0.0262
Echinococcus granulosus protein jagged 2 0.0357 0.0685 0.0685
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0257 0.0393 0.0393
Schistosoma mansoni hypothetical protein 0.0196 0.0214 0.0203
Entamoeba histolytica protein kinase domain containing protein 0.0244 0.0354 0.1734
Schistosoma mansoni tyrosine kinase 0.0194 0.0208 0.0197
Onchocerca volvulus 0.0135 0.0035 0.0048
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0422 0.0876 0.0866
Echinococcus multilocularis transfer RNA-Phe 0.0182 0.0174 0.0174
Echinococcus multilocularis activin receptor type 0.0136 0.0037 0.0037
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0646 0.1534 0.1534
Schistosoma mansoni basigin related 0.0196 0.0214 0.0203
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0262 0.0408 0.0398
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.021 0.0254 0.0254
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0482 0.1054 0.1054
Schistosoma mansoni netrin receptor unc5 0.0256 0.039 0.038
Brugia malayi Protein kinase domain containing protein 0.0401 0.0816 0.0806
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0247 0.0364 0.0354
Loa Loa (eye worm) hypothetical protein 0.0289 0.0486 0.0476
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0693 0.1672 0.1663
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0357 0.0685 0.0676
Schistosoma mansoni tyrosine kinase 0.062 0.1459 0.145
Loa Loa (eye worm) hypothetical protein 0.0247 0.0365 0.0354
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0453 0.0967 0.0957
Brugia malayi Protein kinase domain containing protein 0.0656 0.1563 0.1554
Echinococcus granulosus casein kinase ii subunit alpha 0.0208 0.025 0.025
Schistosoma mansoni g1/s-specific cyclin C 0.152 0.4098 0.4091
Giardia lamblia Kinase, CMGC CK2 0.0208 0.025 0.0358
Echinococcus granulosus protein kinase C gamma type 0.042 0.0871 0.0871
Schistosoma mansoni hypothetical protein 0.0357 0.0685 0.0676
Loa Loa (eye worm) thioredoxin reductase 0.3531 1 1
Trichomonas vaginalis CMGC family protein kinase 0.0208 0.025 0.0683
Echinococcus granulosus N chimaerin 0.0155 0.0094 0.0094
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0325 0.0592 0.1752
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.036 0.0694 0.0694
Brugia malayi Casein kinase II, alpha chain 0.0208 0.025 0.0239
Brugia malayi Immunoglobulin I-set domain containing protein 0.0182 0.0174 0.0163
Schistosoma mansoni kinase 0.0601 0.1401 0.1392
Plasmodium vivax unspecified product 0.0208 0.025 0.0118
Echinococcus multilocularis cyclin dependent kinase 0.0247 0.0364 0.0364
Echinococcus granulosus dual specificity 0.0289 0.0487 0.0487
Onchocerca volvulus 0.0659 0.1572 0.704
Entamoeba histolytica casein kinase 1, putative 0.0226 0.0302 0.1453
Trichomonas vaginalis AGC family protein kinase 0.0608 0.1422 0.4348
Schistosoma mansoni myosin-binding protein-related 0.0182 0.0174 0.0163
Loa Loa (eye worm) hypothetical protein 0.0297 0.051 0.05
Trichomonas vaginalis AGC family protein kinase 0.0283 0.047 0.1371
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.032 0.0577 0.0541
Schistosoma mansoni protein kinase 0.0179 0.0164 0.0153
Brugia malayi Immunoglobulin I-set domain containing protein 0.021 0.0254 0.0244
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0733 0.1791 0.1782
Echinococcus multilocularis serine:threonine protein kinase N2 0.0335 0.0621 0.0621
Loa Loa (eye worm) hypothetical protein 0.0182 0.0174 0.0163
Echinococcus multilocularis protein jagged 1 0.0357 0.0685 0.0685
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0254 0.0385 0.0349
Brugia malayi Wrapper/rega-1/klingon homolog protein 1 0.0164 0.0119 0.0108
Trichomonas vaginalis CMGC family protein kinase 0.0268 0.0424 0.1228
Trichomonas vaginalis CAMK family protein kinase 0.0162 0.0115 0.0262
Schistosoma mansoni cell adhesion molecule 0.0182 0.0174 0.0163
Schistosoma mansoni serine/threonine protein kinase 0.0562 0.1288 0.1279
Schistosoma mansoni serine/threonine protein kinase 0.0244 0.0354 0.0344
Loa Loa (eye worm) hypothetical protein 0.036 0.0694 0.0684
Trichomonas vaginalis AGC family protein kinase 0.0244 0.0354 0.101
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0247 0.0364 0.0328
Trypanosoma brucei cdc2-related kinase 1 0.0247 0.0364 0.0328
Trichomonas vaginalis CAMK family protein kinase 0.0162 0.0115 0.0262
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0237 0.0335 0.0325
Trypanosoma cruzi polo-like protein kinase, putative 0.0562 0.1288 0.1256
Giardia lamblia Kinase, NEK 0.0283 0.047 0.107
Entamoeba histolytica hypothetical protein 0.0254 0.0385 0.1898
Echinococcus granulosus tyrosine protein kinase Fyn 0.0316 0.0565 0.0565
Echinococcus granulosus Glutaredoxin protein 5 0.0257 0.0393 0.0393
Leishmania major casein kinase, putative 0.0226 0.0302 0.0266
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0301 0.0522 0.0522
Echinococcus granulosus twitchin 0.0878 0.2216 0.2216
Loa Loa (eye worm) hypothetical protein 0.0164 0.0119 0.0108
Entamoeba histolytica PH domain containing protein kinase, putative 0.0342 0.0641 0.3272
Echinococcus multilocularis casein kinase I alpha 0.0226 0.0302 0.0302
Entamoeba histolytica protein kinase, putative 0.0173 0.0146 0.0615
Echinococcus multilocularis titin 0.0164 0.0119 0.0119
Treponema pallidum NADH oxidase 0.1224 0.3229 1
Brugia malayi Protein kinase domain containing protein 0.0187 0.0187 0.0176
Echinococcus multilocularis cyclin dependent kinase 1 0.0247 0.0364 0.0364
Schistosoma mansoni serine/threonine protein kinase 0.0335 0.0621 0.0611
Brugia malayi EGF-like domain containing protein 0.0357 0.0685 0.0676
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0196 0.0214 0.0203
Echinococcus granulosus glutamate synthase 0.0325 0.0592 0.0592
Echinococcus granulosus dual specificity protein kinase clk2 0.032 0.0577 0.0577
Trichomonas vaginalis CAMK family protein kinase 0.0162 0.0115 0.0262
Loa Loa (eye worm) TK/FER protein kinase 0.0135 0.0035 0.0025
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0325 0.0592 0.3008
Echinococcus granulosus mitogen activated protein kinase 14 0.0331 0.061 0.061
Leishmania major protein kinase, putative 0.0176 0.0156 0.0119
Trichomonas vaginalis CAMK family protein kinase 0.0562 0.1288 0.3931
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0704 0.1704 0.1695
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0176 0.0156 0.0666
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.1224 0.3229 0.3138
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0325 0.0592 0.3008
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0289 0.0487 0.0452
Brugia malayi Immunoglobulin I-set domain containing protein 0.0164 0.0119 0.0108
Trichomonas vaginalis AGC family protein kinase 0.0608 0.1422 0.4348
Entamoeba histolytica disulphide oxidoreductase, putative 0.0325 0.0592 0.3008
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0289 0.0487 0.0477
Echinococcus multilocularis hypothetical protein 0.0212 0.026 0.026
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0459 0.0986 0.0986
Leishmania major protein kinase A catalytic subunit isoform 2 0.0235 0.0329 0.0293
Echinococcus granulosus low density lipoprotein receptor ldl 0.0196 0.0214 0.0214
Brugia malayi Protein kinase domain containing protein 0.0763 0.1877 0.1869
Giardia lamblia Kinase, CMGC DYRK 0.0289 0.0487 0.1126
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0268 0.0424 0.0388
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0176 0.0156 0.0119
Loa Loa (eye worm) hypothetical protein 0.0232 0.0321 0.031
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0693 0.1672 0.1663
Onchocerca volvulus 0.0164 0.0119 0.0428
Entamoeba histolytica protein kinase, putative 0.0189 0.0193 0.0867
Brugia malayi Protein kinase domain 0.0179 0.0164 0.0153
Giardia lamblia Kinase, CMGC CDK 0.0247 0.0364 0.0728
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0357 0.0685 0.0676
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0301 0.0523 0.0523
Trypanosoma cruzi hypothetical protein, conserved 0.0325 0.0592 0.0557
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.032 0.0577 0.0541
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.021 0.0254 0.0254
Entamoeba histolytica casein kinase, putative 0.0208 0.025 0.1173
Entamoeba histolytica cell division protein kinase 2, putative 0.0247 0.0364 0.1785
Onchocerca volvulus Putative titin 0.0164 0.0119 0.0428
Echinococcus multilocularis tyrosine protein kinase Abl 0.0194 0.0208 0.0208
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0173 0.0146 0.0109
Loa Loa (eye worm) notch protein 0.0357 0.0685 0.0676
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0226 0.0302 0.0292
Echinococcus multilocularis protein kinase c epsilon type 0.0424 0.0884 0.0884
Loa Loa (eye worm) hypothetical protein 0.0179 0.0163 0.0152
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0325 0.0592 0.0557
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.036 0.0694 0.0684
Brugia malayi Temporarily assigned gene name protein 59 0.0268 0.0426 0.0416
Echinococcus multilocularis lachesin 0.036 0.0694 0.0694
Trichomonas vaginalis AGC family protein kinase 0.0244 0.0354 0.101
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0235 0.0329 0.0293
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.1224 0.3229 1
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0325 0.0592 0.1752
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.017 0.0136 0.0126
Trichomonas vaginalis CAMK family protein kinase 0.0162 0.0115 0.0262
Echinococcus granulosus cyclin dependent kinase 5 0.0247 0.0364 0.0364
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0247 0.0364 0.0328
Schistosoma mansoni serine/threonine protein kinase 0.053 0.1195 0.1186
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0235 0.0329 0.0293
Brugia malayi Fibronectin type III domain containing protein 0.0665 0.1589 0.158
Loa Loa (eye worm) TK protein kinase 0.0257 0.0393 0.0382
Echinococcus multilocularis notch 0.0357 0.0685 0.0685
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.032 0.0577 0.0541
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0325 0.0592 0.0592
Schistosoma mansoni hypothetical protein 0.0357 0.0685 0.0676
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.1224 0.3229 0.3222
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.082 0.2045 0.2045
Echinococcus multilocularis tyrosine protein kinase otk 0.036 0.0694 0.0694
Echinococcus granulosus serine/threonine protein kinase 0.0342 0.0641 0.0641
Echinococcus multilocularis c src tyrosine kinase 0.0194 0.0208 0.0208
Trichomonas vaginalis CAMK family protein kinase 0.0162 0.0115 0.0262
Echinococcus granulosus c-Jun N-terminal kinases 0.055 0.1252 0.1252
Brugia malayi Immunoglobulin I-set domain containing protein 0.0182 0.0174 0.0163
Entamoeba histolytica protein kinase domain containing protein 0.0268 0.0424 0.2109
Loa Loa (eye worm) programmed cell death 8 0.0325 0.0592 0.0582
Leishmania major casein kinase II, putative 0.0208 0.025 0.0213
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1224 0.3229 0.3204
Brugia malayi Animal haem peroxidase family protein 0.0164 0.0119 0.0108
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0335 0.0621 0.0621
Brugia malayi hypothetical protein 0.0659 0.1572 0.1563
Loa Loa (eye worm) hypothetical protein 0.0665 0.1589 0.158
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0376 0.0742 0.0742
Loa Loa (eye worm) hypothetical protein 0.036 0.0696 0.0686
Schistosoma mansoni hemicentin 0.0182 0.0174 0.0163
Loa Loa (eye worm) hypothetical protein 0.0251 0.0375 0.0365
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0235 0.0329 0.0293
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0376 0.0742 0.0742
Echinococcus multilocularis 0.0251 0.0375 0.0375
Plasmodium falciparum casein kinase 2, alpha subunit 0.0208 0.025 0.0213
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0178 0.016 0.0149
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1224 0.3229 0.3204
Brugia malayi Disorganized muscle protein 1 0.0164 0.0119 0.0108
Entamoeba histolytica PH domain containing protein kinase, putative 0.0342 0.0641 0.3272
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0257 0.0393 0.0393
Loa Loa (eye worm) hypothetical protein 0.1006 0.2589 0.2582
Echinococcus granulosus mitogen activated protein kinase 11 0.0331 0.061 0.061
Brugia malayi hypothetical protein 0.0659 0.1572 0.1563
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.021 0.0254 0.0123
Trypanosoma cruzi cdc2-related kinase 1 0.0247 0.0364 0.0328
Echinococcus multilocularis titin 0.0164 0.0119 0.0119
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0378 0.0749 0.0749
Echinococcus granulosus casein kinase I delta 0.0226 0.0302 0.0302
Schistosoma mansoni titin 0.0164 0.0119 0.0108
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0462 0.0995 0.0995
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0208 0.025 0.0239
Brugia malayi putative serine/threonine kinase SADA gamma 0.0162 0.0115 0.0105
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.055 0.1252 0.1242
Plasmodium falciparum calcium-dependent protein kinase 4 0.021 0.0254 0.0218
Echinococcus granulosus cyclin dependent kinase 0.0247 0.0364 0.0364
Loa Loa (eye worm) hypothetical protein 0.04 0.0812 0.0802
Echinococcus granulosus slit 2 protein 0.0403 0.082 0.082
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.032 0.0577 0.0541
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0763 0.1877 0.1877
Brugia malayi protein-tyrosine kinase 0.0257 0.0393 0.0382
Schistosoma mansoni serine/threonine protein kinase 0.0341 0.064 0.063
Loa Loa (eye worm) hypothetical protein 0.0357 0.0685 0.0676
Giardia lamblia Kinase, NEK 0.0283 0.047 0.107
Entamoeba histolytica protein kinase, putative 0.0244 0.0354 0.1734
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0157 0.0101 0.0064
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0232 0.0321 0.0285
Brugia malayi Immunoglobulin I-set domain containing protein 0.0251 0.0375 0.0365
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.1224 0.3229 0.2803
Echinococcus granulosus mitogen activated protein kinase 3 0.0174 0.015 0.015
Trichomonas vaginalis CAMK family protein kinase 0.0162 0.0115 0.0262
Echinococcus granulosus cyclin 0.0758 0.1862 0.1862
Trichomonas vaginalis mercuric reductase, putative 0.1224 0.3229 1
Brugia malayi Serine/threonine-protein kinase SULU 0.0462 0.0995 0.0985
Trichomonas vaginalis AGC family protein kinase 0.0608 0.1422 0.4348
Loa Loa (eye worm) hypothetical protein 0.0665 0.1589 0.158
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1224 0.3229 0.3204
Echinococcus granulosus serine:threonine protein kinase 3 0.0534 0.1206 0.1206
Loa Loa (eye worm) hypothetical protein 0.0646 0.1534 0.1525
Echinococcus granulosus tyrosine protein kinase 0.0315 0.0564 0.0564
Trypanosoma cruzi trypanothione reductase, putative 0.1224 0.3229 0.3204
Brugia malayi hypothetical protein 0.0659 0.1572 0.1563
Schistosoma mansoni serine/threonine protein kinase 0.0235 0.0329 0.0318
Trichomonas vaginalis CMGC family protein kinase 0.0208 0.025 0.0683
Onchocerca volvulus 0.0164 0.0121 0.0436
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0325 0.0592 0.0557
Trypanosoma cruzi polo-like protein kinase, putative 0.0562 0.1288 0.1256
Schistosoma mansoni tyrosine kinase 0.0316 0.0565 0.0555
Brugia malayi Protein kinase domain containing protein 0.0335 0.0621 0.0611
Toxoplasma gondii rhoptry neck protein RON1 0.0659 0.1572 0.154
Echinococcus granulosus serine:threonine protein kinase N2 0.027 0.043 0.043
Schistosoma mansoni hypothetical protein 0.0164 0.0119 0.0108
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1224 0.3229 0.3204
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0232 0.0321 0.0321
Onchocerca volvulus 0.0325 0.0592 0.258
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0899 0.2276 0.2268
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.1224 0.3229 0.3138
Schistosoma mansoni septate junction protein 0.036 0.0694 0.0684
Loa Loa (eye worm) one IG domain family member 0.0164 0.0119 0.0108
Trichomonas vaginalis CMGC family protein kinase 0.032 0.0577 0.1705
Schistosoma mansoni tyrosine kinase 0.0431 0.0903 0.0893
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0167 0.0127 0.0127
Echinococcus granulosus MAP kinase activated protein kinase 2 0.082 0.2045 0.2045
Echinococcus multilocularis titin 0.0164 0.0119 0.0119
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0283 0.047 0.0434
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0342 0.0641 0.0606
Schistosoma mansoni tyrosine kinase 0.0413 0.0852 0.0842
Echinococcus granulosus neurogenic locus protein delta 0.0357 0.0685 0.0685
Brugia malayi hypothetical protein 0.0659 0.1572 0.1563
Plasmodium vivax glutathione reductase, putative 0.3531 1 1
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0135 0.0035 0.0035
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0325 0.0592 0.0592
Loa Loa (eye worm) TK/FER protein kinase 0.0135 0.0035 0.0025
Plasmodium falciparum ferrodoxin reductase-like protein 0.0325 0.0592 0.0557
Onchocerca volvulus 0.0164 0.0119 0.0428
Onchocerca volvulus 0.0357 0.0685 0.3007
Entamoeba histolytica serine/threonine protein kinase, putative 0.0562 0.1288 0.6749
Trichomonas vaginalis CAMK family protein kinase 0.057 0.1312 0.4006
Schistosoma mansoni tyrosine kinase 0.0194 0.0208 0.0197
Brugia malayi Protein kinase domain containing protein 0.1034 0.2672 0.2665
Trypanosoma cruzi casein kinase, putative 0.0226 0.0302 0.0266
Echinococcus granulosus aurora kinase A 0.0244 0.0354 0.0354
Echinococcus granulosus oligomeric golgi complex subunit 3 0.0758 0.1862 0.1862
Brugia malayi basement membrane proteoglycan precursor 0.0196 0.0214 0.0203
Echinococcus multilocularis mitogen activated protein kinase 11 0.0331 0.061 0.061
Trichomonas vaginalis CMGC family protein kinase 0.0247 0.0364 0.104
Schistosoma mansoni hypothetical protein 0.0164 0.0119 0.0108
Schistosoma mansoni serine/threonine protein kinase 0.017 0.0136 0.0126
Loa Loa (eye worm) hypothetical protein 0.0357 0.0685 0.0676
Toxoplasma gondii aurora kinase 0.0244 0.0354 0.0318
Schistosoma mansoni serine/threonine protein kinase 0.0232 0.032 0.031
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0247 0.0364 0.0364
Brugia malayi Cadherin domain containing protein 0.0357 0.0686 0.0676
Brugia malayi Cyclin C 0.152 0.4098 0.4091
Schistosoma mansoni titin 0.0164 0.0119 0.0108
Loa Loa (eye worm) TK/FER protein kinase 0.0135 0.0035 0.0025
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0842 0.2109 0.2109
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0325 0.0592 0.0592
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0196 0.0214 0.0203
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0196 0.0214 0.0214
Leishmania major acetoin dehydrogenase e3 component-like protein 0.1224 0.3229 0.3204
Schistosoma mansoni serine/threonine protein kinase 0.0281 0.0462 0.0452
Echinococcus multilocularis rac serine:threonine kinase 0.0342 0.0641 0.0641
Onchocerca volvulus Neurogenic locus notch homolog 0.0357 0.0685 0.3007
Schistosoma mansoni ephrin receptor 0.02 0.0227 0.0216
Trypanosoma cruzi hypothetical protein, conserved 0.0325 0.0592 0.0557
Brugia malayi Kinase associated domain 1 family protein 0.0212 0.026 0.025
Loa Loa (eye worm) hypothetical protein 0.0232 0.0321 0.031
Echinococcus granulosus growth factor receptor bound protein 2 0.0129 0.0017 0.0017
Echinococcus multilocularis mitogen activated protein kinase 0.0174 0.015 0.015
Schistosoma mansoni serine/threonine protein kinase 0.0444 0.094 0.0931
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1224 0.3229 0.3204
Echinococcus granulosus tyrosine protein kinase shark 0.0356 0.0684 0.0684
Echinococcus multilocularis protein jagged 2 0.0357 0.0685 0.0685
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.032 0.0577 0.0541
Brugia malayi Protein kinase c protein 2 0.0241 0.0345 0.0335
Giardia lamblia Thioredoxin reductase 0.0325 0.0592 0.1464
Trichomonas vaginalis CAMK family protein kinase 0.0239 0.0341 0.0969
Trypanosoma brucei rac serine-threonine kinase, putative 0.0608 0.1422 0.139
Schistosoma mansoni hypothetical protein 0.0357 0.0685 0.0676
Trypanosoma brucei polo-like protein kinase 0.0562 0.1288 0.1256
Entamoeba histolytica protein kinase domain containing protein 0.0268 0.0424 0.2109
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.021 0.0254 0.0123
Echinococcus granulosus protein kinase 0.0319 0.0574 0.0574
Onchocerca volvulus Peroxidasin homolog 0.0164 0.0119 0.0428
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0244 0.0354 0.1734
Brugia malayi hypothetical protein 0.0196 0.0214 0.0203
Echinococcus granulosus fibropellin Ia 0.0357 0.0685 0.0685
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0287 0.0482 0.1408
Brugia malayi Immunoglobulin I-set domain containing protein 0.0182 0.0174 0.0163
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.021 0.0254 0.0244
Schistosoma mansoni protein kinase 0.0134 0.0031 0.0021
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0422 0.0876 0.0876
Loa Loa (eye worm) hypothetical protein 0.0357 0.0685 0.0676
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0247 0.0364 0.0354
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0325 0.0592 0.1752
Brugia malayi kettin 0.0164 0.0119 0.0108
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.1959 0.5388 0.5383
Trypanosoma brucei SNF1-related protein kinases, putative 0.0162 0.0115 0.0078
Loa Loa (eye worm) hypothetical protein 0.0196 0.0214 0.0203
Echinococcus multilocularis serine threonine protein kinase 0.042 0.0871 0.0871
Echinococcus multilocularis Opioid binding protein:cell adhesion molecule 0.0164 0.0119 0.0119
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0182 0.0174 0.0163
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0231 0.0316 0.0316
Echinococcus granulosus lachesin 0.036 0.0694 0.0694
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0179 0.0164 0.0164
Echinococcus granulosus tyrosine protein kinase ABL1 0.0135 0.0035 0.0035
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0376 0.0742 0.0742
Echinococcus multilocularis cyclin dependent kinase 1 0.0247 0.0364 0.0364
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0247 0.0364 0.0328
Trichomonas vaginalis CAMK family protein kinase 0.0451 0.0963 0.2914
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.021 0.0254 0.0218
Entamoeba histolytica protein kinase, putative 0.015 0.0078 0.0248
Echinococcus granulosus Immunoglobulin 0.0196 0.0214 0.0214
Loa Loa (eye worm) hypothetical protein 0.0297 0.051 0.05
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0226 0.0302 0.0292
Brugia malayi Immunoglobulin I-set domain containing protein 0.0378 0.0749 0.0739
Schistosoma mansoni titin 0.0164 0.0119 0.0108
Giardia lamblia Glutamate synthase 0.0325 0.0592 0.1464
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.1034 0.2672 0.2665
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0418 0.0864 0.0864
Schistosoma mansoni vav2 0.0171 0.014 0.0129
Echinococcus granulosus tyrosine protein kinase Src42A 0.0192 0.0201 0.0201
Brugia malayi protein unc-22 0.0251 0.0375 0.0365
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.1224 0.3229 0.2803
Brugia malayi Immunoglobulin I-set domain containing protein 0.0378 0.0749 0.0739
Echinococcus granulosus serine threonine protein kinase nrc 0.0326 0.0595 0.0595
Echinococcus multilocularis dual specificity protein kinase clk2 0.032 0.0577 0.0577
Echinococcus multilocularis hemicentin 1 0.036 0.0694 0.0694
Brugia malayi Protein kinase domain containing protein 0.0135 0.0035 0.0025
Toxoplasma gondii NADPH-glutathione reductase 0.1224 0.3229 0.3204
Schistosoma mansoni titin 0.0164 0.0119 0.0108
Loa Loa (eye worm) hypothetical protein 0.0357 0.0685 0.0676
Schistosoma mansoni serine/threonine protein kinase 0.0226 0.0302 0.0292
Schistosoma mansoni serine/threonine protein kinase 0.0462 0.0995 0.0985
Echinococcus granulosus titin 0.0164 0.0119 0.0119
Loa Loa (eye worm) TK/FER protein kinase 0.0449 0.0957 0.0947
Onchocerca volvulus 0.04 0.0812 0.3582
Echinococcus granulosus protein kinase shaggy 0.0268 0.0424 0.0424
Echinococcus granulosus Immunoglobulin subtype 0.0196 0.0214 0.0214
Echinococcus granulosus 3'partial|cell adhesion molecule:down regulated by 0.0196 0.0214 0.0214
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0174 0.015 0.0113
Echinococcus granulosus roundabout 2 0.1024 0.2644 0.2644
Echinococcus granulosus calcium dependent protein kinase 0.0141 0.0053 0.0053
Echinococcus multilocularis cell adhesion molecule:down regulated by 0.0196 0.0214 0.0214
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0162 0.0115 0.0115
Schistosoma mansoni tyrosine kinase 0.0132 0.0027 0.0017
Brugia malayi hypothetical protein 0.0659 0.1572 0.1563
Echinococcus granulosus tyrosine protein kinase Fyn 0.0316 0.0565 0.0565
Echinococcus granulosus serine:threonine protein kinase 0.0237 0.0335 0.0335
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0733 0.1791 0.8037
Echinococcus multilocularis Down syndrome cell adhesion molecule 0.0215 0.0269 0.0269
Plasmodium falciparum serine/threonine protein kinase KIN 0.0162 0.0115 0.0078
Onchocerca volvulus 0.0135 0.0035 0.0048
Trichomonas vaginalis CMGC family protein kinase 0.0174 0.015 0.037
Schistosoma mansoni serine/threonine protein kinase 0.0992 0.255 0.2542
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0301 0.0522 0.0522
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0453 0.0967 0.0957
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0449 0.0957 0.0957
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0325 0.0592 0.0557
Onchocerca volvulus 0.0357 0.0685 0.3007
Loa Loa (eye worm) CDC7 protein kinase 0.0187 0.0187 0.0176
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0325 0.0592 0.0592
Brugia malayi Fes/CIP4 homology domain containing protein 0.0212 0.0262 0.0251
Trichomonas vaginalis CMGC family protein kinase 0.0247 0.0364 0.104
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0232 0.0321 0.031
Echinococcus multilocularis Immunoglobulin 0.0646 0.1534 0.1534
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.1224 0.3229 0.3204
Echinococcus granulosus nervana 2 0.0257 0.0393 0.0393
Echinococcus granulosus NDR protein kinase 0.0335 0.0621 0.0621
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0164 0.0119 0.0108
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0899 0.2276 0.2268
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0316 0.0565 0.0565
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0325 0.0592 0.0465
Echinococcus multilocularis cyclin dependent kinase 5 0.0247 0.0364 0.0364
Trichomonas vaginalis AGC family protein kinase 0.0608 0.1422 0.4348
Trichomonas vaginalis CAMK family protein kinase 0.0162 0.0115 0.0262
Echinococcus multilocularis 0.0319 0.0574 0.0574
Entamoeba histolytica protein kinase, putative 0.0289 0.0487 0.2446
Leishmania major dihydrolipoamide dehydrogenase, putative 0.1224 0.3229 0.3204
Loa Loa (eye worm) TK/KIN16 protein kinase 0.1559 0.4212 0.4206
Loa Loa (eye worm) hypothetical protein 0.0164 0.0119 0.0108
Loa Loa (eye worm) AUR protein kinase 0.0244 0.0354 0.0344
Brugia malayi Protein kinase domain containing protein 0.0247 0.0364 0.0354
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0155 0.0094 0.0094
Schistosoma mansoni nephrin 0.0378 0.0749 0.0739
Echinococcus multilocularis slit 2 protein 0.0403 0.082 0.082
Echinococcus granulosus contactin 0.0378 0.0749 0.0749
Onchocerca volvulus 0.0251 0.0375 0.1595
Echinococcus multilocularis casein kinase I alpha 0.0226 0.0302 0.0302
Loa Loa (eye worm) gastrulation defective protein 1 0.0965 0.2471 0.2463
Trichomonas vaginalis AGC family protein kinase 0.0372 0.0729 0.2182
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0268 0.0424 0.0388
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0646 0.1534 0.1525
Onchocerca volvulus 0.0659 0.1572 0.704
Loa Loa (eye worm) cyclin C 0.152 0.4098 0.4091
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0179 0.0164 0.0164
Brugia malayi Leucine Rich Repeat family protein 0.0164 0.0121 0.011
Trichomonas vaginalis CAMK family protein kinase 0.0162 0.0115 0.0262
Schistosoma mansoni septate junction protein 0.0357 0.0685 0.0676
Brugia malayi Protein kinase domain containing protein 0.0173 0.0146 0.0136
Schistosoma mansoni serine/threonine protein kinase 0.0289 0.0487 0.0477
Schistosoma mansoni serine/threonine protein kinase 0.0489 0.1073 0.1064
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.1224 0.3229 1
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.021 0.0254 0.0218
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0196 0.0214 0.0203
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.036 0.0694 0.0684
Echinococcus multilocularis dual specificity 0.0289 0.0487 0.0487
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0262 0.0408 0.0408
Trichomonas vaginalis CAMK family protein kinase 0.0562 0.1288 0.3931
Loa Loa (eye worm) hypothetical protein 0.0164 0.0119 0.0108
Schistosoma mansoni serine/threonine protein kinase 0.0162 0.0115 0.0105
Loa Loa (eye worm) hypothetical protein 0.0264 0.0413 0.0403
Echinococcus granulosus Vam6:Vps39 protein 0.0232 0.0321 0.0321
Toxoplasma gondii EGF family domain-containing protein 0.0357 0.0685 0.0651
Plasmodium vivax serine/threonine protein kinase, putative 0.0173 0.0146 0.0013
Brugia malayi casein kinase I 0.0226 0.0302 0.0292
Schistosoma mansoni serine/threonine protein kinase 0.0507 0.1126 0.1116
Onchocerca volvulus 0.0659 0.1572 0.704
Schistosoma mansoni hypothetical protein 0.0357 0.0685 0.0676
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.3531 1 1
Entamoeba histolytica protein kinase, putative 0.021 0.0254 0.1197
Echinococcus multilocularis C type lectin domian containing protein 0.0659 0.1572 0.1572
Trichomonas vaginalis CMGC family protein kinase 0.0289 0.0487 0.1425
Brugia malayi map kinase activated protein kinase protein 2 0.082 0.2045 0.2036
Loa Loa (eye worm) TK protein kinase 0.0381 0.0758 0.0748
Brugia malayi Protein kinase domain containing protein 0.017 0.0136 0.0126
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0562 0.1288 0.1279
Brugia malayi Variant SH3 domain containing protein 0.0155 0.0094 0.0083
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0173 0.0146 0.0109
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.036 0.0694 0.0684
Loa Loa (eye worm) hypothetical protein 0.0357 0.0685 0.0676
Loa Loa (eye worm) hypothetical protein 0.0357 0.0685 0.0676
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0418 0.0864 0.0864
Echinococcus granulosus neurogenic locus notch protein 0.0357 0.0685 0.0685
Schistosoma mansoni cell adhesion molecule 0.0164 0.0119 0.0108
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0174 0.015 0.0113
Schistosoma mansoni neuroglian 0.0378 0.0749 0.0739
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.021 0.0254 0.0254
Schistosoma mansoni serine/threonine-protein kinase 0.0342 0.0641 0.0631
Brugia malayi Protein kinase domain containing protein 0.0597 0.1392 0.1383
Onchocerca volvulus 0.0182 0.0174 0.0679
Brugia malayi Calcium binding EGF domain containing protein 0.0357 0.0685 0.0676
Brugia malayi Protein kinase domain containing protein 0.0135 0.0035 0.0025
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0325 0.0592 0.0557
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0164 0.0119 0.0119
Brugia malayi Immunoglobulin I-set domain containing protein 0.036 0.0694 0.0684
Loa Loa (eye worm) TK/ALK protein kinase 0.0312 0.0554 0.0544
Echinococcus multilocularis PAK box P21 Rho binding 0.0134 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0164 0.0119 0.0108
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0235 0.0329 0.0329
Brugia malayi Protein kinase domain containing protein 0.0444 0.094 0.0931
Schistosoma mansoni hypothetical protein 0.0196 0.0214 0.0203
Trichomonas vaginalis CK1 family protein kinase 0.0226 0.0302 0.0846
Trichomonas vaginalis CK1 family protein kinase 0.0226 0.0302 0.0846
Echinococcus granulosus tyrosine protein kinase HCK 0.0189 0.0193 0.0193
Echinococcus granulosus CDC7 cell division cycle 7 0.0187 0.0187 0.0187
Schistosoma mansoni hypothetical protein 0.0182 0.0174 0.0163
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0316 0.0565 0.0565
Schistosoma mansoni protein kinase 0.0244 0.0354 0.0344
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0325 0.0592 0.0557
Onchocerca volvulus 0.0164 0.0119 0.0428
Echinococcus multilocularis glutamate synthase 0.0325 0.0592 0.0592
Brugia malayi Myb-like DNA-binding domain containing protein 0.0164 0.0119 0.0108
Brugia malayi Furin-like cysteine rich region family protein 0.0714 0.1733 0.1724
Onchocerca volvulus Putative cubilin 0.0357 0.0685 0.3007
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0162 0.0115 0.0078
Brugia malayi probable protein kinase 0.0551 0.1256 0.1246
Echinococcus multilocularis epidermal growth factor receptor 0.0714 0.1733 0.1733
Loa Loa (eye worm) hypothetical protein 0.0164 0.0119 0.0108
Trypanosoma cruzi cdc2-related kinase 3 0.0247 0.0364 0.0328
Schistosoma mansoni serine/threonine protein kinase 0.0162 0.0115 0.0105
Trichomonas vaginalis STE family protein kinase 0.0179 0.0164 0.0414
Loa Loa (eye worm) hypothetical protein 0.0733 0.1789 0.178
Echinococcus granulosus casein kinase i 0.0226 0.0302 0.0302
Schistosoma mansoni titin 0.0182 0.0174 0.0163
Plasmodium falciparum casein kinase 1 0.0226 0.0302 0.0266
Schistosoma mansoni septate junction protein 0.0196 0.0214 0.0203
Trichomonas vaginalis AGC family protein kinase 0.017 0.0136 0.0327
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0257 0.0393 0.0393
Entamoeba histolytica protein kinase, putative 0.0244 0.0354 0.1734
Loa Loa (eye worm) TK/ABL protein kinase 0.0135 0.0035 0.0025
Schistosoma mansoni serine/threonine protein kinase 0.0507 0.1126 0.1116
Brugia malayi STE20-like kinase MST 0.0534 0.1206 0.1197
Schistosoma mansoni titin 0.0164 0.0119 0.0108
Echinococcus granulosus casein kinase I gamma 0.0444 0.094 0.094
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0316 0.0565 0.0565
Schistosoma mansoni serine/threonine protein kinase 0.0254 0.0385 0.0375
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0639 0.1514 0.1514
Echinococcus granulosus c4b binding protein beta chain 0.0659 0.1572 0.1572
Echinococcus multilocularis casein kinase I gamma 0.0444 0.094 0.094
Trichomonas vaginalis AGC family protein kinase 0.0356 0.0683 0.2038
Loa Loa (eye worm) hypothetical protein 0.0289 0.0486 0.0476
Brugia malayi basement membrane proteoglycan 0.0196 0.0214 0.0203
Echinococcus granulosus tyrosine kinase 0.0135 0.0035 0.0035
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0231 0.0316 0.0316
Plasmodium falciparum glutathione reductase 0.3531 1 1
Echinococcus multilocularis Glutaredoxin protein 5 0.0257 0.0393 0.0393
Entamoeba histolytica cyclin C, putative 0.0769 0.1894 1
Echinococcus multilocularis 0.0164 0.0119 0.0119
Loa Loa (eye worm) hypothetical protein 0.0482 0.1054 0.1045
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0325 0.0592 0.0592
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0357 0.0685 0.3007
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0316 0.0565 0.0565
Schistosoma mansoni tyrosine kinase 0.0356 0.0684 0.0674
Echinococcus granulosus tyrosine protein kinase Srms 0.0557 0.1274 0.1274
Echinococcus multilocularis growth factor receptor bound protein 2 0.0127 0.0011 0.0011
Echinococcus multilocularis N chimaerin 0.0155 0.0094 0.0094
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0422 0.0876 0.0866
Brugia malayi Immunoglobulin I-set domain containing protein 0.0182 0.0174 0.0163
Entamoeba histolytica protein kinase domain containing protein 0.0422 0.0876 0.4532
Schistosoma mansoni serine/threonine protein kinase 0.0281 0.0462 0.0452
Echinococcus multilocularis oligomeric golgi complex subunit 3 0.0758 0.1862 0.1862
Brugia malayi Protein kinase domain containing protein 0.1959 0.5388 0.5383
Echinococcus granulosus leucine rich repeat containing protein 4 0.0164 0.0119 0.0119
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0215 0.0269 0.0258
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0174 0.0149 0.0149
Onchocerca volvulus 0.0164 0.0119 0.0428
Onchocerca volvulus 0.0268 0.0424 0.1818
Leishmania major hypothetical protein, conserved 0.0325 0.0592 0.0557
Onchocerca volvulus 0.0384 0.0766 0.3372
Trichomonas vaginalis CAMK family protein kinase 0.0162 0.0115 0.0262
Echinococcus granulosus protein jagged 1 0.0357 0.0685 0.0685
Trypanosoma cruzi cdc2-related kinase 3 0.0247 0.0364 0.0328
Onchocerca volvulus 0.0232 0.0321 0.1346
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0283 0.047 0.0341
Schistosoma mansoni serine/threonine protein kinase 0.0174 0.0149 0.0138
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0325 0.0592 0.0557
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0325 0.0592 0.0557
Trichomonas vaginalis CAMK family protein kinase 0.0562 0.1288 0.3931
Trichomonas vaginalis STE family protein kinase 0.0179 0.0164 0.0414
Echinococcus multilocularis insulin growth factor binding 0.0164 0.0119 0.0119
Trichomonas vaginalis CMGC family protein kinase 0.0289 0.0487 0.1425
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0449 0.0957 0.0957
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0335 0.0621 0.0621
Brugia malayi Protein kinase domain containing protein 0.0254 0.0385 0.0375
Onchocerca volvulus 0.0357 0.0685 0.3007
Echinococcus granulosus casein kinase I delta 0.0226 0.0302 0.0302
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0173 0.0146 0.0136
Schistosoma mansoni sulfide quinone reductase 0.0325 0.0592 0.0582
Echinococcus multilocularis expressed protein 0.0173 0.0146 0.0146
Trichomonas vaginalis AGC family protein kinase 0.0244 0.0354 0.101
Brugia malayi Protein kinase domain containing protein 0.032 0.0577 0.0567
Loa Loa (eye worm) hypothetical protein 0.0186 0.0184 0.0173
Schistosoma mansoni serine/threonine protein kinase 0.0154 0.0091 0.008
Echinococcus multilocularis protein kinase c iota type 0.0594 0.1382 0.1382
Echinococcus multilocularis serine:threonine protein kinase 0.0237 0.0335 0.0335
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0235 0.0329 0.0293
Schistosoma mansoni basigin related 0.0196 0.0214 0.0203
Brugia malayi Egg laying defective protein 4 0.0174 0.0149 0.0138
Trypanosoma cruzi casein kinase, putative 0.0226 0.0302 0.0266
Onchocerca volvulus Serine\/threonine kinase homolog 0.0562 0.1288 0.5751
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0239 0.0341 0.0341
Brugia malayi Calcium binding EGF domain containing protein 0.0357 0.0685 0.0676
Loa Loa (eye worm) hypothetical protein 0.0403 0.082 0.0811
Echinococcus granulosus hypothetical protein 0.0251 0.0375 0.0375
Echinococcus multilocularis calcium activated potassium channel 0.0281 0.0462 0.0462
Schistosoma mansoni serine/threonine protein kinase 0.0449 0.0957 0.0948
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0289 0.0487 0.0477
Loa Loa (eye worm) AGC/PKG protein kinase 0.0174 0.0149 0.0138
Brugia malayi Immunoglobulin I-set domain containing protein 0.036 0.0694 0.0684
Echinococcus granulosus tyrosine protein kinase Src42A 0.0316 0.0565 0.0565
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0174 0.0149 0.0149
Loa Loa (eye worm) TK protein kinase 0.0189 0.0193 0.0182
Echinococcus granulosus C type lectin domian containing protein 0.0659 0.1572 0.1572
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0326 0.0595 0.056
Loa Loa (eye worm) hypothetical protein 0.0162 0.0115 0.0105
Schistosoma mansoni serine/threonine protein kinase 0.0335 0.0621 0.0611
Trichomonas vaginalis AGC family protein kinase 0.0244 0.0354 0.101
Echinococcus granulosus roundabout 2 0.0378 0.0749 0.0749
Brugia malayi Prion-like- 0.0164 0.0119 0.0108
Onchocerca volvulus 0.0135 0.0035 0.0048
Schistosoma mansoni slit 0.0164 0.0121 0.011
Loa Loa (eye worm) TK/EGFR protein kinase 0.0714 0.1733 0.1724
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0325 0.0592 0.3008
Brugia malayi Protein kinase domain containing protein 0.0315 0.0564 0.0554
Loa Loa (eye worm) hypothetical protein 0.0164 0.0119 0.0108
Echinococcus granulosus titin 0.0164 0.0119 0.0119
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0325 0.0592 0.1752
Echinococcus granulosus Immunoglobulin 0.0646 0.1534 0.1534
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0733 0.1791 0.1782
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0162 0.0115 0.0078
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.1224 0.3229 0.3204
Echinococcus granulosus calcium activated potassium channel 0.0281 0.0462 0.0462
Loa Loa (eye worm) hypothetical protein 0.036 0.0694 0.0684
Schistosoma mansoni tyrosine kinase 0.0316 0.0565 0.0555
Schistosoma mansoni nephrin related 0.0196 0.0214 0.0203
Brugia malayi hypothetical protein 0.0462 0.0995 0.0985
Echinococcus multilocularis mitogen activated protein kinase 14 0.0331 0.061 0.061
Brugia malayi Immunoglobulin domain containing protein 0.0196 0.0214 0.0203
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0316 0.0565 0.0565
Schistosoma mansoni serine/threonine protein kinase 0.0247 0.0364 0.0354
Brugia malayi Protein kinase domain containing protein 0.0418 0.0864 0.0854
Trypanosoma cruzi cdc2-related kinase 1 0.0247 0.0364 0.0328
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0289 0.0487 0.0452
Schistosoma mansoni serine/threonine kinase 0.0335 0.0621 0.0611
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0162 0.0115 0.0078
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0235 0.0329 0.0329
Echinococcus multilocularis serine:threonine protein kinase N2 0.027 0.043 0.043
Trichomonas vaginalis CAMK family protein kinase 0.0239 0.0341 0.0969
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0268 0.0424 0.0414
Schistosoma mansoni hypothetical protein 0.0196 0.0214 0.0203
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0316 0.0565 0.0565
Schistosoma mansoni serine/threonine protein kinase 0.0489 0.1073 0.1064
Echinococcus multilocularis c4b binding protein beta chain 0.0659 0.1572 0.1572
Schistosoma mansoni hypothetical protein 0.0164 0.0119 0.0108
Echinococcus granulosus titin 0.0251 0.0375 0.0375
Trypanosoma cruzi trypanothione reductase, putative 0.3531 1 1
Trichomonas vaginalis CAMK family protein kinase 0.0162 0.0115 0.0262
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0135 0.0035 0.0021
Brugia malayi Immunoglobulin I-set domain containing protein 0.036 0.0694 0.0684
Echinococcus granulosus mitogen activated protein kinase 0.0174 0.015 0.015
Plasmodium falciparum calcium-dependent protein kinase 5 0.021 0.0254 0.0218
Echinococcus multilocularis Immunoglobulin subtype 0.0196 0.0214 0.0214
Loa Loa (eye worm) hypothetical protein 0.0665 0.1589 0.158
Schistosoma mansoni cell adhesion molecule 0.0196 0.0214 0.0203
Brugia malayi serine/threonine kinase 12 0.0244 0.0354 0.0344
Trichomonas vaginalis CAMK family protein kinase 0.0162 0.0115 0.0262
Schistosoma mansoni nephrin related 0.0164 0.0119 0.0108
Plasmodium falciparum protein serine/threonine kinase-1 0.032 0.0577 0.0541
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0326 0.0595 0.0468
Schistosoma mansoni netrin receptor unc5 0.0196 0.0214 0.0203
Loa Loa (eye worm) hypothetical protein 0.0357 0.0685 0.0676
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0378 0.0749 0.0749
Trichomonas vaginalis CAMK family protein kinase 0.0237 0.0335 0.095
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0325 0.0592 0.0557
Brugia malayi notch-like transmembrane receptor 0.0357 0.0685 0.0676
Brugia malayi Immunoglobulin I-set domain containing protein 0.0665 0.1589 0.158
Echinococcus granulosus nervana 2 0.0257 0.0393 0.0393
Echinococcus multilocularis serine:threonine protein kinase 3 0.0534 0.1206 0.1206
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0254 0.0385 0.0349
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0483 0.1055 0.1046
Loa Loa (eye worm) TK/FAK protein kinase 0.0597 0.1392 0.1383
Loa Loa (eye worm) hypothetical protein 0.0357 0.0685 0.0676
Trichomonas vaginalis CMGC family protein kinase 0.0208 0.025 0.0683
Brugia malayi Calcium binding EGF domain containing protein 0.0357 0.0685 0.0676
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0162 0.0115 0.0105
Loa Loa (eye worm) hypothetical protein 0.0357 0.0685 0.0676
Toxoplasma gondii selenide, water dikinase 0.0325 0.0592 0.0557
Loa Loa (eye worm) hypothetical protein 0.0357 0.0685 0.0676
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0378 0.0749 0.0749
Brugia malayi Temporarily assigned gene name protein 59 0.0232 0.0321 0.031
Trichomonas vaginalis STE family protein kinase 0.0179 0.0164 0.0414
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0422 0.0876 0.0876
Echinococcus multilocularis thioredoxin glutathione reductase 0.3531 1 1
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0244 0.0354 0.0224
Loa Loa (eye worm) hypothetical protein 0.0357 0.0685 0.0676
Brugia malayi Sushi domain 0.0659 0.1572 0.1563
Trypanosoma cruzi NADH dehydrogenase, putative 0.0325 0.0592 0.0557
Giardia lamblia Aurora kinase 0.0244 0.0354 0.0696
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0155 0.0094 0.0094
Leishmania major dihydrolipoamide dehydrogenase, putative 0.1224 0.3229 0.3204
Brugia malayi C1-like domain containing protein 0.0453 0.0967 0.0957
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.021 0.0254 0.0123
Brugia malayi Protein kinase domain containing protein 0.0135 0.0035 0.0025
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0179 0.0164 0.0164
Trypanosoma brucei aurora B kinase 0.0244 0.0354 0.0318
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0182 0.0174 0.0174
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0174 0.015 0.0139
Echinococcus granulosus casein kinase I alpha 0.0226 0.0302 0.0302
Giardia lamblia Kinase, CMGC SRPK 0.0173 0.0146 0.0022
Brugia malayi Immunoglobulin I-set domain containing protein 0.0164 0.0119 0.0108
Echinococcus granulosus dual specificity 0.0254 0.0385 0.0385
Trypanosoma cruzi casein kinase II, putative 0.0208 0.025 0.0213
Toxoplasma gondii thioredoxin reductase 0.3531 1 1
Entamoeba histolytica protein kinase, putative 0.015 0.0078 0.0248
Echinococcus multilocularis insulin receptor 0.062 0.1459 0.1459
Giardia lamblia Kinase, CDC7 0.0187 0.0187 0.0154
Brugia malayi Immunoglobulin domain containing protein 0.0196 0.0214 0.0203
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.082 0.2045 0.2036
Echinococcus granulosus tyrosine protein kinase Src64B 0.0316 0.0565 0.0565
Echinococcus multilocularis neurogenic locus notch protein 0.0357 0.0685 0.0685
Echinococcus multilocularis protein kinase shaggy 0.0268 0.0424 0.0424
Onchocerca volvulus 0.0182 0.0174 0.0679
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0182 0.0174 0.0163
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0167 0.0127 0.0127
Schistosoma mansoni serine/threonine protein kinase 0.0235 0.0329 0.0318
Trichomonas vaginalis CMGC family protein kinase 0.0208 0.025 0.0683
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0194 0.0208 0.0197
Loa Loa (eye worm) hypothetical protein 0.036 0.0694 0.0684
Schistosoma mansoni serine/threonine kinase 0.0459 0.0987 0.0977
Schistosoma mansoni growth factor receptor-bound protein 0.0129 0.0017 0.0006
Schistosoma mansoni serine/threonine protein kinase 0.0424 0.0884 0.0874
Loa Loa (eye worm) hypothetical protein 0.0357 0.0685 0.0676
Trichomonas vaginalis CMGC family protein kinase 0.0174 0.015 0.037
Schistosoma mansoni nephrin 0.0828 0.2069 0.2061
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0534 0.1206 0.1197
Echinococcus multilocularis low density lipoprotein receptor (ldl) 0.0196 0.0214 0.0214
Loa Loa (eye worm) glutathione reductase 0.3531 1 1
Echinococcus multilocularis twitchin 0.0232 0.032 0.032
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0325 0.0592 0.0592
Entamoeba histolytica protein kinase, putative 0.0212 0.0262 0.1238
Loa Loa (eye worm) AGC/NDR protein kinase 0.0335 0.0621 0.0611
Brugia malayi Immunoglobulin I-set domain containing protein 0.054 0.1222 0.1213
Brugia malayi Stress-activated protein kinase jnk-1 0.055 0.1252 0.1242
Trichomonas vaginalis STE family protein kinase 0.0283 0.047 0.1371
Brugia malayi Protein kinase domain containing protein 0.0312 0.0555 0.0544
Plasmodium vivax serine/threonine kinase-1, putative 0.032 0.0577 0.0449
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0316 0.0565 0.0565
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0244 0.0354 0.1734
Onchocerca volvulus 0.0659 0.1572 0.704
Loa Loa (eye worm) TK/FER protein kinase 0.0135 0.0035 0.0025
Trypanosoma brucei casein kinase I, isoform 2 0.0226 0.0302 0.0266
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0325 0.0592 0.0557
Echinococcus multilocularis tyrosine kinase 0.0135 0.0035 0.0035
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0251 0.0375 0.0365
Brugia malayi Protein kinase domain containing protein 0.0135 0.0035 0.0025
Echinococcus multilocularis fibropellin Ia 0.0357 0.0685 0.0685
Schistosoma mansoni notch 0.0357 0.0685 0.0676
Loa Loa (eye worm) thyroid receptor interactor 0.0212 0.0262 0.0251
Echinococcus granulosus fibroblast growth factor receptor 4 0.0376 0.0742 0.0742
Echinococcus granulosus tyrosine protein kinase Lyn 0.0384 0.0766 0.0766
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0401 0.0816 0.0806
Loa Loa (eye worm) hypothetical protein 0.0164 0.0119 0.0108
Brugia malayi Protein kinase domain containing protein 0.0656 0.1563 0.1554
Schistosoma mansoni basigin related 0.0196 0.0214 0.0203
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0174 0.015 0.0113
Brugia malayi Prion-like- 0.036 0.0694 0.0684
Brugia malayi Heparan sulfate 0.0196 0.0214 0.0203
Brugia malayi serine/threonine-protein kinase 6 0.0244 0.0354 0.0344
Loa Loa (eye worm) TK protein kinase 0.054 0.1222 0.1213
Schistosoma mansoni serine/threonine protein kinase 0.0247 0.0364 0.0354
Echinococcus granulosus c src tyrosine kinase 0.0194 0.0208 0.0208
Loa Loa (eye worm) hypothetical protein 0.0357 0.0686 0.0676
Leishmania major hypothetical protein, conserved 0.0325 0.0592 0.0557
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0235 0.0329 0.0293
Schistosoma mansoni hypothetical protein 0.0196 0.0214 0.0203
Loa Loa (eye worm) CAMK protein kinase 0.0251 0.0375 0.0365
Loa Loa (eye worm) hypothetical protein 0.0357 0.0685 0.0676
Leishmania major trypanothione reductase 0.3531 1 1
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0326 0.0595 0.0595
Brugia malayi GCC2 and GCC3 family protein 0.1015 0.2619 0.2611
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0196 0.0214 0.0214
Trichomonas vaginalis AGC family protein kinase 0.0608 0.1422 0.4348
Schistosoma mansoni cell adhesion molecule 0.0378 0.0749 0.0739
Loa Loa (eye worm) AGC/PKN protein kinase 0.0604 0.1412 0.1403
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0232 0.0321 0.0285
Onchocerca volvulus 0.0649 0.1545 0.6916
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.021 0.0254 0.0244
Echinococcus granulosus protein jagged 1 0.0357 0.0685 0.0685
Schistosoma mansoni cell polarity protein 0.0357 0.0685 0.0676
Brugia malayi Protein kinase domain containing protein 0.0356 0.0683 0.0673
Plasmodium vivax apical sushi protein, putative 0.0659 0.1572 0.1458
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0325 0.0592 0.0582
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0507 0.1126 0.1126
Brugia malayi Protein kinase domain containing protein 0.0237 0.0335 0.0325
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0325 0.0592 0.0557
Plasmodium falciparum serine/threonine protein kinase 0.0173 0.0146 0.0109
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0316 0.0565 0.0565
Schistosoma mansoni protein kinase 0.0903 0.2287 0.2279
Loa Loa (eye worm) TK/FER protein kinase 0.0135 0.0035 0.0025
Onchocerca volvulus 0.0157 0.0101 0.0345
Loa Loa (eye worm) hypothetical protein 0.0186 0.0184 0.0173
Trypanosoma cruzi casein kinase, putative 0.0226 0.0302 0.0266
Onchocerca volvulus 0.0659 0.1572 0.704
Schistosoma mansoni protein kinase C mu 0.0453 0.0967 0.0957
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.032 0.0577 0.0541
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0325 0.0592 0.0582
Brugia malayi serine/threonine-protein kinase PAK 7 0.0483 0.1055 0.1046
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0335 0.0621 0.0621
Brugia malayi Immunoglobulin I-set domain containing protein 0.0164 0.0119 0.0108
Onchocerca volvulus Basement membrane proteoglycan homolog 0.036 0.0694 0.3046
Plasmodium falciparum calcium-dependent protein kinase 1 0.021 0.0254 0.0218
Echinococcus multilocularis neuroglian 0.0378 0.0749 0.0749
Entamoeba histolytica protein kinase, putative 0.0254 0.0385 0.1898
Loa Loa (eye worm) hypothetical protein 0.0182 0.0174 0.0163
Brugia malayi Immunoglobulin I-set domain containing protein 0.0164 0.0119 0.0108
Onchocerca volvulus 0.0659 0.1572 0.704
Trichomonas vaginalis CMGC family protein kinase 0.0187 0.0187 0.0486
Brugia malayi Immunoglobulin I-set domain containing protein 0.1559 0.4212 0.4206
Plasmodium falciparum glutathione reductase 0.1224 0.3229 0.3204
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.1224 0.3229 1
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0325 0.0592 0.0592
Echinococcus multilocularis neurogenic locus notch protein 0.0357 0.0685 0.0685
Schistosoma mansoni tyrosine kinase 0.0591 0.1373 0.1364
Echinococcus granulosus neurogenic locus notch protein 4 0.0357 0.0685 0.0685
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0164 0.0119 0.0108
Schistosoma mansoni tyrosine kinase 0.0288 0.0484 0.0474
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0268 0.0424 0.0388
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.1224 0.3229 0.2803
Schistosoma mansoni serine/threonine protein kinase 0.055 0.1252 0.1242
Trichomonas vaginalis AGC family protein kinase 0.017 0.0136 0.0327
Schistosoma mansoni rap gtpase-activating protein 0.0232 0.0321 0.031
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0155 0.0094 0.0083
Schistosoma mansoni protein kinase 0.0136 0.0037 0.0027
Brugia malayi Immunoglobulin I-set domain containing protein 0.0164 0.0119 0.0108
Schistosoma mansoni hypothetical protein 0.0164 0.0119 0.0108
Echinococcus multilocularis mitogen activated protein kinase 11 0.0331 0.061 0.061
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0316 0.0565 0.0565

Activities

Activity type Activity value Assay description Source Reference
MIC (functional) = 6.25 ug ml-1 Antifungal activity against Candida albicans assessed as growth inhibition by serial plate dilution method ChEMBL. No reference
MIC (functional) = 12.5 ug ml-1 Antibacterial activity against Escherichia coli ATCC 25922 assessed as growth inhibition by serial plate dilution method ChEMBL. No reference
TIME (functional) = 2.075 s Analgesic activity in Mus musculus Wistar albino (mouse) assessed as time taken to tail withdrawl at 100 mg/kg, po administered through intragastric tube after 120 min by tail flick test (Rvb = 1.363 +/- 0.1297 secs) ChEMBL. No reference
TIME (functional) = 2.175 s Analgesic activity in Mus musculus Wistar albino (mouse) assessed as time taken to tail withdrawl at 100 mg/kg, po administered through intragastric tube after 60 min by tail flick test (Rvb = 1.363 +/- 0.1297 secs) ChEMBL. No reference
Time (functional) = 2.238 s Analgesic activity in Mus musculus Wistar albino (mouse) assessed as time taken to tail withdrawl at 100 mg/kg, po administered through intragastric tube after 180 min by tail flick test (Rvb = 1.363 +/- 0.1297 secs) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.