Detailed information for compound 1806127

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 351.523 | Formula: C21H37NO3
  • H donors: 0 H acceptors: 1 LogP: 4.76 Rotable bonds: 10
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCCN(CC1=CC(OC)OC(C1=O)C1CCCCC1)CCCC
  • InChi: 1S/C21H37NO3/c1-4-6-13-22(14-7-5-2)16-18-15-19(24-3)25-21(20(18)23)17-11-9-8-10-12-17/h15,17,19,21H,4-14,16H2,1-3H3
  • InChiKey: AZXUSQTVENPVLL-UHFFFAOYSA-N  

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0142 0.0619 0.2894
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0084 0.2332
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0053 0.0204 0.0952
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0124 0.2803
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.016 0.3623
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.016 0.3623
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0057 0.0221 0.0897
Schistosoma mansoni chromobox protein 0.0011 0.0007 0.0027
Trypanosoma cruzi DNA damage repair protein, putative 0.0014 0.0019 0.0426
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0087 0.0359 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0124 0.2803
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0221 0.6162
Trypanosoma cruzi DNA polymerase eta, putative 0.0043 0.0154 0.3486
Echinococcus multilocularis Smad4 0.0018 0.0039 0.0158
Echinococcus granulosus Chromo domain 0.0011 0.0007 0.0027
Mycobacterium ulcerans DNA polymerase IV 0.0044 0.016 0.016
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0057 0.0221 0.6162
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0043 0.0154 0.0552
Brugia malayi TAR-binding protein 0.0068 0.0271 0.1446
Echinococcus multilocularis tar DNA binding protein 0.0068 0.0271 0.1099
Schistosoma mansoni chromobox protein 0.0011 0.0007 0.0027
Loa Loa (eye worm) hypothetical protein 0.0468 0.2138 1
Schistosoma mansoni hypothetical protein 0.0538 0.2463 1
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0057 0.0221 0.5003
Loa Loa (eye worm) hypothetical protein 0.0057 0.0221 0.1033
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0145 1
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0057 0.0221 0.6162
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0057 0.0221 0.5003
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0057 0.0221 0.0897
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0057 0.0221 0.5003
Leishmania major cAMP-specific phosphodiesterase, putative 0.0057 0.0221 0.5003
Brugia malayi MH1 domain containing protein 0.001 0.0002 0.0008
Trichomonas vaginalis glutathione reductase, putative 0.0036 0.0124 0.3453
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0124 0.2803
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0057 0.0221 0.6162
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0057 0.0221 0.6162
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0007 0.0188
Brugia malayi Bloom's syndrome protein homolog 0.0023 0.0064 0.034
Mycobacterium tuberculosis Probable reductase 0.0238 0.1065 0.1485
Brugia malayi Associated with TFs and helicases family protein 0.0011 0.0007 0.0036
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.007 0.028 0.9421
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0057 0.0221 0.0793
Echinococcus granulosus protein kinase c iota type 0.0014 0.0021 0.0085
Giardia lamblia hypothetical protein 0.0057 0.0221 0.1033
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0468 0.2138 0.868
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0073 0.0297 0.1205
Brugia malayi Protein kinase c protein 2 0.0045 0.0167 0.0889
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0057 0.0221 0.6162
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.007 0.0281 0.7844
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0057 0.0221 0.118
Plasmodium falciparum thioredoxin reductase 0.0104 0.0442 1
Schistosoma mansoni DNA polymerase eta 0.0073 0.0295 0.1198
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0036 0.0124 0.0503
Loa Loa (eye worm) hypothetical protein 0.0056 0.0216 0.1008
Mycobacterium tuberculosis Conserved hypothetical protein 0.0044 0.016 0.0223
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0007 0.0188
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0057 0.0221 0.0897
Echinococcus granulosus TGF beta signal transducer SmadC 0.0018 0.0039 0.0158
Echinococcus granulosus bloom syndrome protein 0.0023 0.0064 0.0258
Loa Loa (eye worm) animal heme peroxidase 0.0026 0.0076 0.0356
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0036 0.0124 0.2803
Trypanosoma brucei unspecified product 0.003 0.0096 0.2184
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0017 0.0034 0.0137
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0011 0.0007 0.0024
Loa Loa (eye worm) hypothetical protein 0.0011 0.0007 0.0031
Echinococcus granulosus protein kinase C gamma type 0.0048 0.0177 0.0718
Loa Loa (eye worm) helicase 0.0011 0.0007 0.0031
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0019 0.0426
Trypanosoma cruzi PAB1-binding protein , putative 0.0024 0.0069 0.1563
Schistosoma mansoni hypothetical protein 0.0036 0.0125 0.0508
Trypanosoma cruzi DNA polymerase eta, putative 0.0073 0.0295 0.6683
Loa Loa (eye worm) animal heme peroxidase 0.0026 0.0076 0.0356
Treponema pallidum UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.2155 1 1
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0084 0.2332
Loa Loa (eye worm) hypothetical protein 0.001 0.0002 0.0007
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0468 0.2138 0.7671
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0057 0.0221 0.0793
Entamoeba histolytica hypothetical protein 0.0011 0.0007 0.0227
Loa Loa (eye worm) hypothetical protein 0.0026 0.0076 0.0356
Echinococcus multilocularis chromobox protein 2 0.0011 0.0007 0.0027
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0076 0.0407
Onchocerca volvulus Dual oxidase homolog 0.0026 0.0076 0.5257
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.008 0.2233
Echinococcus multilocularis smad 0.0018 0.0039 0.0158
Loa Loa (eye worm) glutathione reductase 0.0104 0.0442 0.2066
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0057 0.0221 0.5003
Leishmania major DNA polymerase eta, putative 0.0043 0.0154 0.3486
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0039 0.0139 0.0652
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0084 0.2332
Onchocerca volvulus Peroxidasin homolog 0.0026 0.0076 0.5257
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0238 0.1065 0.1485
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0076 0.0407
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0007 0.0188
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.007 0.028 0.7801
Echinococcus multilocularis chromobox protein 1 0.0067 0.027 0.1095
Onchocerca volvulus 0.0011 0.0007 0.0465
Trypanosoma brucei unspecified product 0.003 0.0096 0.2184
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0057 0.0221 0.0793
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0084 0.2332
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0057 0.0221 0.0897
Plasmodium vivax thioredoxin reductase, putative 0.0104 0.0442 1
Trypanosoma cruzi DNA damage repair protein, putative 0.0014 0.0019 0.0426
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0036 0.0124 0.0503
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0057 0.0221 0.0793
Schistosoma mansoni serine/threonine protein kinase 0.0053 0.0204 0.0829
Entamoeba histolytica hypothetical protein 0.0011 0.0007 0.0227
Mycobacterium leprae PROBABLE UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE MURA 0.1548 0.7168 1
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0087 0.0359 1
Trichomonas vaginalis MYB72, putative 0.007 0.028 0.7801
Trypanosoma brucei hypothetical protein, conserved 0.0014 0.0019 0.0426
Loa Loa (eye worm) hypothetical protein 0.0026 0.0076 0.0356
Trypanosoma brucei DNA polymerase IV, putative 0.0044 0.016 0.3623
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0007 0.0188
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0057 0.0221 0.0793
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0057 0.0221 0.5003
Trypanosoma cruzi hypothetical protein, conserved 0.0057 0.0221 0.5003
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0271 0.1099
Loa Loa (eye worm) hypothetical protein 0.0053 0.0204 0.0952
Loa Loa (eye worm) hypothetical protein 0.0026 0.0076 0.0356
Brugia malayi Heterochromatin protein 1 0.0067 0.027 0.1441
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0057 0.0221 0.6162
Toxoplasma gondii thioredoxin reductase 0.0104 0.0442 0.1585
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0007 0.0188
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0011 0.0007 0.0027
Trypanosoma brucei DNA polymerase IV, putative 0.0044 0.016 0.3623
Trypanosoma cruzi DNA polymerase kappa, putative 0.0044 0.016 0.3623
Brugia malayi latrophilin 2 splice variant baaae 0.0036 0.0125 0.0668
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0018 0.0039 0.0158
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0057 0.0221 0.0793
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.007 0.028 0.9421
Trichomonas vaginalis leucine-rich repeat protein, BspA family 0.0028 0.0084 0.2332
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0011 0.0007 0.0027
Schistosoma mansoni hypothetical protein 0.0017 0.0034 0.0137
Echinococcus multilocularis proprotein convertase subtilisin:kexin type 5 0.0087 0.0359 0.1456
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0265 0.1188 0.1658
Loa Loa (eye worm) hypothetical protein 0.0044 0.016 0.0749
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0057 0.0221 0.6162
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.0057 0.0221 0.5003
Entamoeba histolytica hypothetical protein 0.0011 0.0007 0.0227
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0018 0.0039 0.0158
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0057 0.0221 0.6162
Wolbachia endosymbiont of Brugia malayi UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.2155 1 1
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0053 0.0204 0.0829
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0036 0.0124 0.0124
Schistosoma mansoni peroxidasin 0.0026 0.0076 0.0309
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0036 0.0124 0.2803
Echinococcus granulosus chromobox protein 1 0.0067 0.027 0.1095
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0057 0.0221 0.6162
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0011 0.0007 0.0027
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0057 0.0221 0.118
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0007 0.0188
Entamoeba histolytica hypothetical protein 0.0073 0.0297 1
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0057 0.0221 0.6162
Onchocerca volvulus 0.003 0.0093 0.6449
Loa Loa (eye worm) latrophilin receptor protein 2 0.0017 0.0034 0.0158
Schistosoma mansoni hypothetical protein 0.0073 0.0297 0.1205
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0057 0.0221 0.5003
Trichomonas vaginalis DNA helicase recq, putative 0.0023 0.0064 0.1774
Plasmodium vivax hypothetical protein, conserved 0.0011 0.0007 0.0152
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0007 0.0188
Plasmodium falciparum heterochromatin protein 1 0.0011 0.0007 0.0152
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.0142 0.0619 0.2512
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0057 0.0221 0.0897
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0084 0.2332
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0013 0.0298
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0057 0.0221 0.118
Echinococcus multilocularis dna polymerase eta 0.0073 0.0295 0.1198
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0044 0.016 0.0748
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0007 0.0188
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0057 0.0221 0.6162
Echinococcus multilocularis peroxidasin 0.0026 0.0076 0.0309
Trichomonas vaginalis chromobox protein, putative 0.0067 0.027 0.7523
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0145 0.4042
Trypanosoma cruzi hypothetical protein, conserved 0.0057 0.0221 0.5003
Loa Loa (eye worm) hypothetical protein 0.0017 0.0034 0.0158
Trypanosoma brucei trypanothione reductase 0.0104 0.0442 1
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0057 0.0221 0.6162
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0057 0.0221 0.0793
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0057 0.0221 0.5003
Loa Loa (eye worm) hypothetical protein 0.0011 0.0007 0.0031
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0221 0.6162
Echinococcus granulosus smad 0.0018 0.0039 0.0158
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0057 0.0221 0.6162
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0411 0.1872 0.7601
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0124 0.2803
Trichomonas vaginalis pc-MYB2, putative 0.007 0.028 0.7801
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0011 0.0007 0.0024
Plasmodium vivax phosphodiesterase gamma, putative 0.0057 0.0221 0.5003
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0057 0.0221 0.6162
Echinococcus multilocularis thioredoxin glutathione reductase 0.0104 0.0442 0.1793
Brugia malayi hypothetical protein 0.0026 0.0076 0.0407
Brugia malayi Latrophilin receptor protein 2 0.0017 0.0034 0.0181
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0057 0.0221 0.118
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0271 0.1099
Loa Loa (eye worm) proprotein convertase 2 0.0034 0.0112 0.0524
Mycobacterium leprae probable 3-phosphoshikimate 1-carboxyvinyl transferase AroA (5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE SYNTHASE) (EPSP SYNTHASE) (EPSPS 0.0608 0.2787 0.3888
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0011 0.0007 0.0152
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0057 0.0221 0.118
Schistosoma mansoni smad1 5 8 and 0.0018 0.0039 0.0158
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0271 0.1099
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0057 0.0221 0.6162
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.002 0.005 0.1143
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0036 0.0124 0.2803
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0057 0.0221 0.6162
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0057 0.0221 0.6162
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0096 0.2184
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0057 0.0221 0.0897
Giardia lamblia DNA damage repair protein 0.0014 0.0019 0.0088
Brugia malayi Smad1 0.0018 0.0039 0.0208
Trichomonas vaginalis mercuric reductase, putative 0.0036 0.0124 0.3453
Entamoeba histolytica hypothetical protein 0.0073 0.0297 1
Trypanosoma brucei DNA polymerase eta, putative 0.0073 0.0295 0.6683
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0036 0.0124 0.2803
Echinococcus multilocularis dna polymerase kappa 0.0044 0.016 0.065
Loa Loa (eye worm) hypothetical protein 0.0011 0.0007 0.0031
Echinococcus multilocularis Chromobox protein 3 0.0011 0.0007 0.0027
Plasmodium falciparum glutathione reductase 0.0104 0.0442 1
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0007 0.0227
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0057 0.0221 0.5003
Schistosoma mansoni peroxidasin 0.0026 0.0076 0.0309
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0011 0.0006 0.0026
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0057 0.0221 0.0897
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.007 0.028 0.7801
Plasmodium vivax heterochromatin protein 1, putative 0.0011 0.0007 0.0152
Schistosoma mansoni hypothetical protein 0.0538 0.2463 1
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0096 0.2184
Mycobacterium tuberculosis Probable oxidoreductase 0.0265 0.1188 0.1658
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0036 0.0124 0.2803
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0057 0.0221 0.6162
Brugia malayi Blistered cuticle protein 3 0.0026 0.0076 0.0407
Echinococcus granulosus Furin 1 0.0034 0.0112 0.0455
Loa Loa (eye worm) MH2 domain-containing protein 0.0018 0.0039 0.0182
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0007 0.0188
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0057 0.0221 0.6162
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0057 0.0221 0.5003
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.0057 0.0221 0.0897
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0057 0.0221 0.0897
Loa Loa (eye worm) endoprotease bli-4 0.0142 0.0619 0.2894
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0124 0.2803
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0007 0.0227
Trypanosoma brucei DNA damage repair protein, putative 0.0014 0.0019 0.0426
Schistosoma mansoni hypothetical protein 0.0011 0.0006 0.0026
Plasmodium vivax DNA repair protein REV1, putative 0.0014 0.0019 0.0426
Echinococcus multilocularis bloom syndrome protein 0.0023 0.0064 0.0258
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0057 0.0221 0.0897
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0011 0.0006 0.0026
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0007 0.0188
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0016 0.0029 0.0646
Loa Loa (eye worm) hypothetical protein 0.0026 0.0076 0.0356
Brugia malayi M-phase phosphoprotein, mpp8 0.0011 0.0007 0.0036
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0271 0.1099
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0057 0.0221 0.0793
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0019 0.0426
Trichomonas vaginalis chromobox protein, putative 0.0011 0.0007 0.0188
Chlamydia trachomatis phosphoshikimate 1-carboxyl vinyltransferase 0.0608 0.2787 0.2787
Loa Loa (eye worm) hypothetical protein 0.0011 0.0007 0.0031
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0057 0.0221 0.118
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.016 0.3623
Schistosoma mansoni blooms syndrome DNA helicase 0.0018 0.0041 0.0166
Echinococcus multilocularis serine threonine protein kinase 0.0048 0.0177 0.0718
Giardia lamblia Myb 1-like protein 0.007 0.0281 0.1315
Loa Loa (eye worm) hypothetical protein 0.0026 0.0076 0.0356
Brugia malayi MH2 domain containing protein 0.0018 0.0039 0.0208
Loa Loa (eye worm) Smad1 0.0018 0.0039 0.0182
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0007 0.0188
Trypanosoma brucei hypothetical protein, conserved 0.0057 0.0221 0.5003
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0057 0.0221 0.6162
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0011 0.0007 0.0188
Leishmania major DNA polymerase kappa, putative 0.0044 0.016 0.3623
Schistosoma mansoni serine/threonine protein kinase 0.0015 0.0027 0.0108
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.0057 0.0221 0.5003
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0011 0.0007 0.0152
Entamoeba histolytica recQ family helicase, putative 0.0012 0.0013 0.0443
Trichomonas vaginalis Heterochromatin protein, putative 0.0011 0.0007 0.0188
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.007 0.028 0.7801
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0057 0.0221 0.5003
Trichomonas vaginalis hypothetical protein 0.0011 0.0007 0.0188
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.007 0.028 0.9421
Entamoeba histolytica hypothetical protein 0.0073 0.0297 1
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0011 0.0007 0.0027
Loa Loa (eye worm) transcription factor SMAD2 0.0263 0.1183 0.5535
Loa Loa (eye worm) MH1 domain-containing protein 0.0018 0.0039 0.0182
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0034 0.0112 0.3123
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0057 0.0221 0.0793
Schistosoma mansoni hypothetical protein 0.0011 0.0007 0.0027
Loa Loa (eye worm) thioredoxin reductase 0.0104 0.0442 0.2066
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0034 0.0112 0.3123
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0007 0.0188
Loa Loa (eye worm) hypothetical protein 0.003 0.0093 0.0437
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0265 0.1188 0.1658
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0057 0.0221 0.5003
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0084 0.2332
Brugia malayi endoprotease bli-4 precursor 0.0142 0.0619 0.3305
Trypanosoma cruzi trypanothione reductase, putative 0.0036 0.0124 0.2803
Trichomonas vaginalis proprotein convertase subtilisin/kexin type, putative 0.0028 0.0084 0.2332
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0057 0.0221 0.0897
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.0069 0.1563
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0034 0.0112 0.3123
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0057 0.0221 0.0897
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0036 0.0124 0.0124
Toxoplasma gondii LsmAD domain-containing protein 0.0024 0.0069 0.0248
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0036 0.0124 0.2803
Mycobacterium ulcerans hypothetical protein 0.0014 0.0019 0.0019
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0057 0.0221 0.6162
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0011 0.0007 0.0188
Leishmania major hypothetical protein, conserved 0.0024 0.0069 0.1563
Echinococcus granulosus proprotein convertase subtilisin:kexin type 5 0.0087 0.0359 0.1456
Brugia malayi Protein cec-1. 0.0011 0.0007 0.0036
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.0069 0.1563
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0036 0.0124 0.2803
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0014 0.0019 0.0067
Leishmania major DNA damage repair protein, putative 0.0014 0.0019 0.0426
Echinococcus multilocularis protein kinase c iota type 0.0014 0.0021 0.0085
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0145 0.4042
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0057 0.0221 0.0793
Echinococcus granulosus thioredoxin glutathione reductase 0.0104 0.0442 0.1793
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0015 0.0027 0.0125
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0057 0.0221 0.6162
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0044 0.016 0.3623
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0013 0.0298
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0265 0.1188 0.1658
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0124 0.2803
Loa Loa (eye worm) cyclic AMP specific phosphodiesterase PDE4D5A 0.0411 0.1872 0.8757
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0038 0.0132 0.9076
Onchocerca volvulus 0.0026 0.0076 0.5257
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.016 0.3623
Schistosoma mansoni chromobox protein 0.0067 0.027 0.1095
Plasmodium vivax ataxin-2 like protein, putative 0.0024 0.0069 0.1563
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0036 0.0124 0.0661
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0044 0.016 0.065
Loa Loa (eye worm) hypothetical protein 0.0026 0.0076 0.0356
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.007 0.028 0.9421
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0057 0.0221 0.5003
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0057 0.0221 0.6162
Loa Loa (eye worm) TAR-binding protein 0.0068 0.0271 0.1267
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0053 0.0204 0.1087
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0027 0.0079 0.0422
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0027 0.0079 0.0422
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0007 0.0188
Loa Loa (eye worm) hypothetical protein 0.0057 0.0221 0.1033
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0011 0.0007 0.0027
Loa Loa (eye worm) hypothetical protein 0.0026 0.0076 0.0356
Echinococcus granulosus peroxidasin 0.0026 0.0076 0.0309
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0011 0.0007 0.0188
Onchocerca volvulus Chorion peroxidase homolog 0.0026 0.0076 0.5257
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0036 0.0124 0.0124
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0057 0.0221 0.6162
Loa Loa (eye worm) hypothetical protein 0.0014 0.0019 0.0088
Echinococcus granulosus Chromobox protein 3 0.0011 0.0007 0.0027
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.016 0.3623
Echinococcus granulosus furin 0.0142 0.0619 0.2512
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0036 0.0124 0.2803
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.0057 0.0221 0.1033
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.008 0.2233
Trichomonas vaginalis DNA helicase recq1, putative 0.0023 0.0064 0.1774
Echinococcus granulosus mothers against decapentaplegic 5 0.0018 0.0039 0.0158
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0068 0.0271 0.1267
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0017 0.0034 0.0137
Loa Loa (eye worm) hypothetical protein 0.0026 0.0076 0.0356
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0084 0.2332
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0044 0.016 0.0223
Brugia malayi hypothetical protein 0.0016 0.0029 0.0153
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0057 0.0221 0.5003
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0034 0.0112 0.3123
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0011 0.0007 0.0188
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0036 0.0124 0.0173
Brugia malayi MH1 domain containing protein 0.0018 0.0039 0.0208
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0057 0.0221 0.0793
Trypanosoma cruzi hypothetical protein, conserved 0.0057 0.0221 0.5003
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0057 0.0221 0.0897
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0044 0.016 0.065
Loa Loa (eye worm) hypothetical protein 0.0038 0.0133 0.0621
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0238 0.1065 0.1485
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0007 0.0227
Trypanosoma cruzi PAB1-binding protein , putative 0.0024 0.0069 0.1563
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0014 0.0019 0.0067
Brugia malayi SET domain containing protein 0.0011 0.0007 0.0036
Loa Loa (eye worm) animal heme peroxidase 0.0026 0.0076 0.0356
Loa Loa (eye worm) hypothetical protein 0.0038 0.0132 0.0615
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0011 0.0007 0.0188
Leishmania major hypothetical protein, conserved 0.0057 0.0221 0.5003
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0057 0.0221 0.6162
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0034 0.0112 0.3123
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0271 0.1099
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0057 0.0221 0.5003
Mycobacterium tuberculosis Probable dehydrogenase 0.0238 0.1065 0.1485
Onchocerca volvulus 0.0026 0.0076 0.5257
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0076 0.0407
Trypanosoma cruzi DNA polymerase kappa, putative 0.0044 0.016 0.3623
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0057 0.0221 0.0793
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0057 0.0221 0.0793
Loa Loa (eye worm) hypothetical protein 0.0024 0.0069 0.0323
Mycobacterium ulcerans UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.2155 1 1
Loa Loa (eye worm) animal heme peroxidase 0.0026 0.0076 0.0356
Echinococcus granulosus dna polymerase kappa 0.0044 0.016 0.065
Trypanosoma cruzi DNA polymerase kappa, putative 0.0044 0.016 0.3623
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0238 0.1065 0.1485
Trichomonas vaginalis C-MYB, putative 0.007 0.028 0.7801
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0017 0.0034 0.0137
Brugia malayi protein kinase C II. 0.0015 0.0027 0.0142
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0076 0.0407
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.016 0.3623
Leishmania major trypanothione reductase 0.0104 0.0442 1
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0011 0.0007 0.0024
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.007 0.028 0.7801
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.007 0.028 0.9421
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0057 0.0221 0.0897
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.007 0.028 0.7801
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0016 0.0028 0.0099
Loa Loa (eye worm) hypothetical protein 0.0011 0.0007 0.0031
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0044 0.016 0.065
Giardia lamblia Furin precursor putative serine protease 0.0028 0.0084 0.0391
Echinococcus granulosus tar DNA binding protein 0.0068 0.0271 0.1099
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0011 0.0007 0.0027
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0036 0.0124 0.2803
Loa Loa (eye worm) hypothetical protein 0.0026 0.0076 0.0356
Brugia malayi Valyl-tRNA synthetase 0.0011 0.0007 0.0036
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0017 0.0034 0.0137
Brugia malayi hypothetical protein 0.0073 0.0297 0.1586
Echinococcus multilocularis 0.0115 0.049 0.1991
Toxoplasma gondii shikimate dehydrogenase substrate binding domain-containing protein 0.0608 0.2787 1
Toxoplasma gondii NADPH-glutathione reductase 0.0036 0.0124 0.0444
Plasmodium falciparum phosphodiesterase gamma, putative 0.0057 0.0221 0.5003
Brugia malayi RNA recognition motif domain containing protein 0.0068 0.0271 0.1446
Loa Loa (eye worm) heterochromatin protein 1 0.0067 0.027 0.1262
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0076 0.0407
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0057 0.0221 0.6162
Echinococcus multilocularis RNA directed DNA polymerase 0.0038 0.0133 0.0539
Brugia malayi MH2 domain containing protein 0.0018 0.0039 0.0208
Onchocerca volvulus 0.0011 0.0007 0.0465
Trichomonas vaginalis neuroendocrine convertase 2 precursor, putative 0.0028 0.0084 0.2332
Trichomonas vaginalis hypothetical protein 0.0028 0.0084 0.2332
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0057 0.0221 0.6162
Brugia malayi MH1 domain containing protein 0.001 0.0002 0.0008
Loa Loa (eye worm) hypothetical protein 0.0073 0.0295 0.1381
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0468 0.2138 0.868
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0411 0.1872 0.7601
Echinococcus granulosus chromobox protein 2 0.0011 0.0007 0.0027
Echinococcus multilocularis neuroendocrine convertase 2 0.0089 0.0372 0.1511
Loa Loa (eye worm) CHromoDomain protein family member 0.0011 0.0007 0.0031
Mycobacterium ulcerans DNA polymerase IV 0.0044 0.016 0.016
Trichomonas vaginalis chromobox protein, putative 0.0011 0.0007 0.0188
Schistosoma mansoni Smad4 0.0018 0.0039 0.0158
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0057 0.0221 0.6162
Loa Loa (eye worm) hypothetical protein 0.0011 0.0007 0.0031
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0036 0.0124 0.0124
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0019 0.0426
Trypanosoma brucei unspecified product 0.0044 0.016 0.3623
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.0057 0.0221 0.5003
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0011 0.0007 0.0036
Schistosoma mansoni smad 0.0018 0.0039 0.0158
Brugia malayi celfurPC protein 0.0115 0.049 0.262
Leishmania major hypothetical protein, conserved 0.0057 0.0221 0.5003
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0104 0.0442 0.0616
Trichomonas vaginalis chromobox protein, putative 0.0067 0.027 0.7523
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0007 0.0188
Echinococcus multilocularis Chromo domain 0.0011 0.0007 0.0027
Loa Loa (eye worm) PDE1B protein 0.0057 0.0221 0.1033
Onchocerca volvulus Peroxidasin homolog 0.0026 0.0076 0.5257
Trypanosoma brucei PAB1-binding protein , putative 0.0024 0.0069 0.1563
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0057 0.0221 0.6162
Echinococcus multilocularis GPCR, family 2 0.0017 0.0034 0.0137
Trypanosoma cruzi hypothetical protein, conserved 0.0057 0.0221 0.5003
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.016 0.3623
Giardia lamblia High cysteine membrane protein Group 2 0.0053 0.0202 0.0944
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0036 0.0124 0.2803
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0011 0.0007 0.0188
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0034 0.0112 0.3123
Loa Loa (eye worm) hypothetical protein 0.0026 0.0076 0.0356
Schistosoma mansoni hypothetical protein 0.0017 0.0034 0.0137
Echinococcus granulosus geminin 0.0538 0.2463 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.016 0.3623
Echinococcus multilocularis chromobox protein 1 0.0067 0.027 0.1095
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0057 0.0221 0.0793
Trichomonas vaginalis C-MYB, putative 0.007 0.028 0.7801
Schistosoma mansoni smad1 5 8 and 0.0018 0.0039 0.0158
Loa Loa (eye worm) hypothetical protein 0.0117 0.0501 0.2342
Brugia malayi hypothetical protein 0.0011 0.0007 0.0036
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0411 0.1872 1
Plasmodium falciparum thioredoxin reductase 0.0036 0.0124 0.2803
Trichomonas vaginalis chromobox protein, putative 0.0011 0.0007 0.0188
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0036 0.0124 0.0503
Schistosoma mansoni subfamily S8B non-peptidase homologue (S08 family) 0.0034 0.0112 0.0455
Loa Loa (eye worm) blistered cuticle protein 3 0.0026 0.0076 0.0356
Brugia malayi Peroxidasin 0.0026 0.0076 0.0407
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0011 0.0007 0.0188
Brugia malayi MH2 domain containing protein 0.0263 0.1183 0.632
Echinococcus granulosus chromobox protein 1 0.0067 0.027 0.1095
Loa Loa (eye worm) RecQ helicase 0.0023 0.0064 0.0298
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.016 0.3623
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0057 0.0221 0.6162
Schistosoma mansoni serine/threonine protein kinase 0.0053 0.0204 0.0829
Leishmania major DNA polymerase eta, putative 0.0073 0.0295 0.6683
Echinococcus multilocularis Furin 1 0.0034 0.0112 0.0455
Trypanosoma brucei DNA damage repair protein, putative 0.0014 0.0019 0.0426
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0238 0.1065 0.1485
Brugia malayi Thioredoxin reductase 0.0104 0.0442 0.2359
Brugia malayi chromobox protein homolog 3 0.0038 0.0132 0.0703
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0057 0.0221 0.6162
Brugia malayi RNA binding protein 0.0068 0.0271 0.1446
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0468 0.2138 0.868
Toxoplasma gondii Myb family DNA-binding domain-containing protein 0.007 0.0281 0.1009
Plasmodium vivax glutathione reductase, putative 0.0104 0.0442 1
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0057 0.0221 0.5003
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0057 0.0221 0.6162
Giardia lamblia DINP protein human, muc B family 0.0044 0.016 0.0748
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0057 0.0221 0.0793
Plasmodium falciparum phosphodiesterase delta, putative 0.0057 0.0221 0.5003
Loa Loa (eye worm) hypothetical protein 0.0026 0.0076 0.0356
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0468 0.2138 0.868
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0057 0.0221 0.0897
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0468 0.2138 0.868
Brugia malayi MH1 domain containing protein 0.0018 0.0039 0.0208
Echinococcus granulosus Smad4 0.0018 0.0039 0.0158
Schistosoma mansoni transcription factor LCR-F1 0.0073 0.0297 0.1205
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0011 0.0007 0.0027
Echinococcus granulosus protein kinase c epsilon type 0.0015 0.0027 0.0108
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0057 0.0221 0.5003
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0011 0.0007 0.0027
Loa Loa (eye worm) nuclear factor I 0.001 0.0002 0.0007
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0468 0.2138 1
Schistosoma mansoni smad1 5 8 and 0.0018 0.0039 0.0158
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0057 0.0221 0.0897
Trichomonas vaginalis DNA helicase recq, putative 0.0012 0.0013 0.0367
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0057 0.0221 0.6162
Brugia malayi neuroendocrine convertase 1 precursor 0.0089 0.0372 0.1988
Onchocerca volvulus 0.0011 0.0007 0.0465
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0019 0.0426
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0011 0.0007 0.0188
Loa Loa (eye worm) hypothetical protein 0.0026 0.0076 0.0356
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0057 0.0221 0.5003
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.0057 0.0221 0.0897
Plasmodium falciparum DNA repair protein REV1, putative 0.0014 0.0019 0.0426
Echinococcus multilocularis protein kinase c epsilon type 0.0015 0.0027 0.0108
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0057 0.0221 0.5003
Loa Loa (eye worm) hypothetical protein 0.0057 0.0221 0.1033
Echinococcus granulosus GPCR family 2 0.0017 0.0034 0.0137
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0057 0.0221 0.0897
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0057 0.0221 0.0897
Trypanosoma cruzi DNA polymerase kappa, putative 0.0044 0.016 0.3623
Trichomonas vaginalis DNA polymerase eta, putative 0.0044 0.016 0.4463
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.007 0.028 0.7801
Entamoeba histolytica hypothetical protein 0.0073 0.0297 1
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0238 0.1065 0.1485
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0221 0.6162
Schistosoma mansoni terminal deoxycytidyl transferase 0.0044 0.016 0.065
Trypanosoma brucei chrX additional, unordered contigs 0.0014 0.0019 0.0426
Brugia malayi CHD4 protein 0.0011 0.0007 0.0036
Trichomonas vaginalis pc-MYB2, putative 0.007 0.028 0.7801
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0057 0.0221 0.0897
Trypanosoma brucei hypothetical protein, conserved 0.0014 0.0019 0.0426
Treponema pallidum NADH oxidase 0.0036 0.0124 0.0124
Trypanosoma cruzi hypothetical protein, conserved 0.0057 0.0221 0.5003
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.0057 0.0221 0.0897
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0036 0.0124 0.0444
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0044 0.016 0.4463
Echinococcus multilocularis mothers against decapentaplegic 5 0.0018 0.0039 0.0158
Mycobacterium ulcerans 3-phosphoshikimate 1-carboxyvinyltransferase 0.0608 0.2787 0.2787
Trichomonas vaginalis MYB3r3, putative 0.007 0.028 0.7801
Brugia malayi polk-prov protein 0.0014 0.0019 0.01
Loa Loa (eye worm) hypothetical protein 0.0011 0.0007 0.0031
Giardia lamblia Hypothetical protein 0.0057 0.0221 0.1033
Plasmodium vivax hypothetical protein, conserved 0.0011 0.0007 0.0152
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0132 0.3669
Schistosoma mansoni chromobox protein 0.0067 0.027 0.1095
Brugia malayi ImpB/MucB/SamB family protein 0.0073 0.0295 0.1576
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.0038 0.0133 0.0539
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.007 0.0281 0.7844
Entamoeba histolytica deoxycytidyl transferase, putative 0.0044 0.016 0.539
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0036 0.0124 0.2803
Schistosoma mansoni hypothetical protein 0.0017 0.0034 0.0137
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0057 0.0221 0.6162
Echinococcus granulosus Protein kinase C brain isozyme 0.0053 0.0204 0.0829
Echinococcus granulosus RNA directed DNA polymerase 0.0038 0.0133 0.0539
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0036 0.0124 0.2803
Schistosoma mansoni hypothetical protein 0.0028 0.0084 0.0339
Loa Loa (eye worm) hypothetical protein 0.0026 0.0076 0.0356
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0073 0.0297 0.1205
Schistosoma mansoni hypothetical protein 0.0017 0.0034 0.0137
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0096 0.2184
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0036 0.0124 0.2803
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0057 0.0221 0.6162
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.016 0.3623
Schistosoma mansoni furin-1 (S08 family) 0.0062 0.0244 0.099
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0057 0.0221 0.6162
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0057 0.0221 0.0793
Mycobacterium tuberculosis Probable UDP-N-acetylglucosamine 1-carboxyvinyltransferase MurA 0.1548 0.7168 1
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0057 0.0221 0.6162
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0132 0.3669
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0036 0.0124 0.0124
Brugia malayi Calcitonin receptor-like protein seb-1 0.0053 0.0204 0.1087
Loa Loa (eye worm) RNA binding protein 0.0068 0.0271 0.1267
Leishmania major DNA polymerase kappa, putative 0.0014 0.0019 0.0426
Onchocerca volvulus Peroxidase homolog 0.0026 0.0076 0.5257
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0057 0.0221 0.6162
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0036 0.0124 0.0124
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0084 0.2332
Brugia malayi proprotein convertase 2 0.0089 0.0372 0.1988
Brugia malayi glutathione reductase 0.0104 0.0442 0.2359
Onchocerca volvulus Peroxidase homolog 0.0026 0.0076 0.5257
Loa Loa (eye worm) MH2 domain-containing protein 0.0263 0.1183 0.5535
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0084 0.2332
Schistosoma mansoni DNA polymerase IV / kappa 0.0014 0.0019 0.0076
Giardia lamblia NADH oxidase lateral transfer candidate 0.0036 0.0124 0.0579
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0057 0.0221 0.6162
Echinococcus multilocularis geminin 0.0538 0.2463 1
Onchocerca volvulus 0.0026 0.0076 0.5257
Echinococcus granulosus neuroendocrine convertase 2 0.0089 0.0372 0.1511
Trypanosoma cruzi trypanothione reductase, putative 0.0104 0.0442 1
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0057 0.0221 0.6162
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0036 0.0124 0.2803
Plasmodium falciparum glutathione reductase 0.0036 0.0124 0.2803
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0084 0.2332
Loa Loa (eye worm) hypothetical protein 0.0026 0.0076 0.0356
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0057 0.0221 0.6162
Schistosoma mansoni atypical protein kinase C 0.0014 0.0021 0.0085
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0084 0.2332
Brugia malayi hypothetical protein 0.0024 0.0069 0.0369
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0013 0.0298
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0011 0.0007 0.0027
Loa Loa (eye worm) hypothetical protein 0.0036 0.0125 0.0585
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.0057 0.0221 0.5003
Trypanosoma cruzi hypothetical protein, conserved 0.0057 0.0221 0.5003
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0057 0.0221 0.6162
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0057 0.0221 0.0793
Echinococcus granulosus dna polymerase eta 0.0073 0.0295 0.1198
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0017 0.0034 0.0181
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0057 0.0221 0.0897
Trypanosoma brucei DNA polymerase IV, putative 0.0044 0.016 0.3623
Trichomonas vaginalis MYB, putative 0.007 0.0281 0.7844
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0057 0.0221 0.6162
Brugia malayi ImpB/MucB/SamB family protein 0.0044 0.016 0.0855

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.