Detailed information for compound 1806362

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 224.662 | Formula: C11H10ClFN2
  • H donors: 0 H acceptors: 1 LogP: 3.42 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 1
  • SMILES: Clc1ccc(c(c1)F)n1nc(cc1C)C
  • InChi: 1S/C11H10ClFN2/c1-7-5-8(2)15(14-7)11-4-3-9(12)6-10(11)13/h3-6H,1-2H3
  • InChiKey: WALQKLLVTNFKKR-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0071 0.3804 0.377
Leishmania major pentamidine resistance protein 1 0.0033 0.099 0.3337
Echinococcus multilocularis multidrug resistance associated protein 7 0.0033 0.099 0.0941
Leishmania major ATP-binding cassette protein subfamily C, member 6, putative 0.0033 0.099 0.3337
Schistosoma mansoni transcription factor LCR-F1 0.0073 0.3966 0.3966
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0059 0.2859 0.282
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0109 0.6635 1
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.004 0.151 0.8819
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0059 0.2859 1
Schistosoma mansoni multidrug resistance protein 0.0059 0.2859 0.2859
Brugia malayi ABC transporter transmembrane region family protein 0.0021 0.0054 0.0137
Loa Loa (eye worm) ABC transporter 0.0021 0.0054 0.0107
Loa Loa (eye worm) hypothetical protein 0.0033 0.099 0.1947
Echinococcus granulosus TRP transient receptor potential channel 0.0033 0.0946 0.0946
Leishmania major trypanothione reductase 0.0043 0.1705 0.5887
Toxoplasma gondii ubiquitin-conjugating enzyme subfamily protein 0.004 0.151 0.3882
Brugia malayi multidrug Resistance Protein family member (mrp-5), putative 0.0021 0.0054 0.0137
Brugia malayi ABC transporter transmembrane region family protein 0.0033 0.099 0.2497
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0059 0.2859 0.282
Entamoeba histolytica multidrug resistance protein, putative 0.0033 0.099 0.2497
Trichomonas vaginalis taga, putative 0.0059 0.2859 1
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0059 0.2859 0.2859
Leishmania major p-glycoprotein 0.0059 0.2859 1
Brugia malayi P-glycoprotein-like protein 0.0021 0.0054 0.0137
Trichomonas vaginalis ABC transporter, putative 0.0059 0.2859 1
Brugia malayi hypothetical protein 0.0073 0.3966 1
Giardia lamblia ABC transporter, putative 0.0033 0.099 1
Leishmania major ATP-binding cassette protein subfamily C, member 1, putative 0.0033 0.099 0.3337
Schistosoma mansoni multidrug resistance protein 0.0033 0.099 0.099
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0038 0.1353 0.4734
Onchocerca volvulus 0.0059 0.2859 0.5
Schistosoma mansoni smdr2 0.0059 0.2859 0.2859
Echinococcus granulosus transient receptor potential ion channel A 0.0085 0.4865 0.4865
Brugia malayi glutathione reductase 0.0043 0.1705 0.4299
Entamoeba histolytica P-glycoprotein-1 0.0059 0.2859 0.7207
Echinococcus multilocularis thioredoxin glutathione reductase 0.0043 0.1705 0.166
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0059 0.2859 1
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0059 0.2859 0.4261
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0059 0.2859 1
Mycobacterium tuberculosis Probable reductase 0.0098 0.5818 0.8758
Schistosoma mansoni transient receptor potential channel 0.0088 0.5085 0.5085
Loa Loa (eye worm) hypothetical protein 0.0088 0.5085 1
Entamoeba histolytica hypothetical protein 0.0073 0.3966 1
Echinococcus granulosus multidrug resistance protein 1 0.0038 0.1353 0.1353
Schistosoma mansoni multidrug resistance protein 0.0059 0.2859 0.2859
Echinococcus granulosus peptidase Clp S14 family 0.0047 0.1975 0.1975
Loa Loa (eye worm) hypothetical protein 0.0059 0.2859 0.5622
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0071 0.3804 1
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0059 0.2859 0.2859
Schistosoma mansoni transient receptor potential channel 4 0.0088 0.5085 0.5085
Loa Loa (eye worm) hypothetical protein 0.0059 0.2859 0.5622
Leishmania major ATP-binding cassette protein subfamily C, member 2, putative 0.0033 0.099 0.3337
Loa Loa (eye worm) hypothetical protein 0.0058 0.2804 0.5515
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0059 0.2859 1
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0098 0.5818 0.8758
Schistosoma mansoni multidrug resistance protein 0.0033 0.099 0.099
Entamoeba histolytica ATP-binding cassette protein, putative 0.0033 0.099 0.2497
Echinococcus granulosus ATP binding cassette sub family B 0.0021 0.0054 0.0054
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.0033 0.099 0.5669
Trichomonas vaginalis abcb9, putative 0.0059 0.2859 1
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0059 0.2859 1
Echinococcus multilocularis multidrug resistance protein 1 0.0059 0.2859 0.282
Loa Loa (eye worm) hypothetical protein 0.0021 0.0054 0.0107
Trypanosoma cruzi trans-sialidase, putative 0.0031 0.0776 0.437
Entamoeba histolytica P-glycoprotein 6, putative 0.0021 0.0054 0.0137
Leishmania major ATP-binding cassette protein subfamily C, member 5, putative 0.0033 0.099 0.3337
Trypanosoma cruzi trans-sialidase, Group I, putative 0.0031 0.0776 0.437
Trypanosoma brucei trans-sialidase, putative 0.0031 0.0776 0.437
Schistosoma mansoni multidrug resistance protein 0.0033 0.099 0.099
Brugia malayi Thioredoxin reductase 0.0043 0.1705 0.4299
Brugia malayi Ubiquitin conjugating enzyme protein 13 0.004 0.151 0.3808
Loa Loa (eye worm) ABC transporter 0.0021 0.0054 0.0107
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0033 0.0946 0.0896
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0059 0.2859 0.282
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0047 0.1975 0.2918
Loa Loa (eye worm) ABC transporter 0.0021 0.0054 0.0107
Schistosoma mansoni ubiquitin conjugating enzyme 13 0.004 0.151 0.151
Plasmodium falciparum multidrug resistance protein 1 0.0059 0.2859 0.7478
Schistosoma mansoni hypothetical protein 0.0154 1 1
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0059 0.2859 1
Brugia malayi Probable ClpP-like protease 0.0071 0.3804 0.9592
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0071 0.3804 1
Trypanosoma cruzi trans-sialidase, putative 0.0031 0.0776 0.437
Plasmodium falciparum glutathione reductase 0.0043 0.1705 0.4402
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.004 0.151 0.5283
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0059 0.2859 1
Loa Loa (eye worm) hypothetical protein 0.0033 0.0946 0.186
Schistosoma mansoni smdr1 0.0021 0.0054 0.0054
Trypanosoma cruzi trans-sialidase, Group I, putative 0.0031 0.0776 0.437
Mycobacterium tuberculosis Probable oxidoreductase 0.0109 0.6635 1
Entamoeba histolytica hypothetical protein 0.0073 0.3966 1
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0059 0.2859 1
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0054 0.019
Trypanosoma cruzi trans-sialidase, Group I, putative 0.0031 0.0776 0.437
Trypanosoma brucei multidrug resistance-associated protein, putative 0.0033 0.099 0.5669
Loa Loa (eye worm) hypothetical protein 0.0033 0.0936 0.184
Echinococcus granulosus ATP binding cassette sub family B 0.0021 0.0054 0.0054
Trypanosoma cruzi trans-sialidase, Group I, putative 0.0031 0.0776 0.437
Loa Loa (eye worm) hypothetical protein 0.0033 0.099 0.1947
Trypanosoma cruzi trans-sialidase, Group I, putative 0.0031 0.0776 0.437
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0071 0.3804 1
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0059 0.2859 1
Giardia lamblia Multidrug resistance-associated protein 1 0.0033 0.099 1
Echinococcus granulosus multidrug resistance protein 1 0.0059 0.2859 0.2859
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0071 0.3804 0.5698
Toxoplasma gondii thioredoxin reductase 0.0043 0.1705 0.4402
Echinococcus multilocularis transient receptor potential ion channel A 0.0085 0.4865 0.4837
Trypanosoma cruzi trypanothione reductase, putative 0.0043 0.1705 1
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0059 0.2859 1
Trypanosoma brucei trans-sialidase 0.0031 0.0776 0.437
Entamoeba histolytica P-glycoprotein-2 0.0059 0.2859 0.7207
Echinococcus granulosus multidrug resistance protein 1 0.0059 0.2859 0.2859
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0059 0.2859 1
Brugia malayi ABC transporter family protein 0.0021 0.0054 0.0137
Echinococcus granulosus multidrug resistance associated protein 7 0.0033 0.099 0.099
Brugia malayi ABC transporter family protein 0.0021 0.0054 0.0137
Leishmania major ABC-thiol transporter 0.0033 0.099 0.3337
Echinococcus granulosus ubiquitin conjugating enzyme E2 N 0.004 0.151 0.151
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0071 0.3804 1
Echinococcus multilocularis multidrug resistance associated protein 1 0.0033 0.099 0.0941
Trypanosoma brucei trypanothione reductase 0.0043 0.1705 1
Trypanosoma brucei trans-sialidase, putative 0.0031 0.0776 0.437
Trypanosoma cruzi trans-sialidase, putative 0.0031 0.0775 0.4368
Echinococcus granulosus short transient receptor potential channel 6 0.0058 0.2854 0.2854
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0043 0.1705 0.2508
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0059 0.2859 1
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0059 0.2859 1
Mycobacterium tuberculosis Probable dehydrogenase 0.0098 0.5818 0.8758
Giardia lamblia MRP-like ABC transporter 0.0033 0.099 1
Entamoeba histolytica P-glycoprotein 5, putative 0.0059 0.2859 0.7207
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0059 0.2859 1
Echinococcus multilocularis transient receptor potential gamma protein 0.0088 0.5085 0.5058
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0059 0.2859 1
Loa Loa (eye worm) multidrug resistance protein 3 0.0059 0.2859 0.5622
Schistosoma mansoni multidrug resistance protein 0.0021 0.0054 0.0054
Trypanosoma cruzi trans-sialidase, Group I, putative 0.0031 0.0776 0.437
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0071 0.3804 0.3804
Entamoeba histolytica P-glycoprotein 6, putative 0.0021 0.0054 0.0137
Entamoeba histolytica ATP-binding cassette protein, putative 0.0033 0.099 0.2497
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.004 0.151 0.297
Trypanosoma cruzi trans-sialidase, Group I, putative 0.0031 0.0776 0.437
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0071 0.3804 1
Echinococcus multilocularis multidrug resistance protein 1 0.0059 0.2859 0.282
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0109 0.6635 1
Brugia malayi ABC transporter 0.0021 0.0054 0.0137
Brugia malayi ABC transporter family protein 0.0059 0.2859 0.7207
Giardia lamblia Multidrug resistance-associated protein 1 0.0033 0.0936 0.9451
Brugia malayi Transient-receptor-potential like protein 0.0033 0.0946 0.2384
Echinococcus multilocularis peptidase Clp (S14 family) 0.0047 0.1975 0.1931
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0071 0.3804 1
Leishmania major ubiquitin-conjugating enzyme e2, putative 0.004 0.151 0.5192
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0071 0.3804 1
Entamoeba histolytica ABC transporter, putative 0.0033 0.099 0.2497
Toxoplasma gondii hypothetical protein 0.0025 0.0324 0.0719
Entamoeba histolytica hypothetical protein 0.0033 0.099 0.2497
Leishmania major p-glycoprotein e 0.0033 0.099 0.3337
Echinococcus granulosus short transient receptor potential channel 6 0.0058 0.2854 0.2854
Plasmodium falciparum ubiquitin-conjugating enzyme E2 N, putative 0.004 0.151 0.3882
Echinococcus granulosus transient receptor potential gamma protein 0.0088 0.5085 0.5085
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0098 0.5818 0.8758
Trichomonas vaginalis ABC transporter, putative 0.0059 0.2859 1
Schistosoma mansoni hypothetical protein 0.0073 0.3966 0.3966
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0059 0.2859 1
Schistosoma mansoni multidrug resistance protein 0.0033 0.099 0.099
Entamoeba histolytica P-glycoprotein-5 0.0059 0.2859 0.7207
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.004 0.151 0.5283
Entamoeba histolytica ubiquitin-conjugating enzyme family protein 0.004 0.151 0.3808
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.0033 0.099 0.5669
Trypanosoma cruzi trans-sialidase, Group I, putative 0.0031 0.0776 0.437
Trypanosoma cruzi trans-sialidase, Group I, putative 0.0031 0.0776 0.437
Echinococcus multilocularis ubiquitin conjugating enzyme E2 N 0.004 0.151 0.1464
Entamoeba histolytica ATP-binding cassette protein, putative 0.0033 0.099 0.2497
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0058 0.2804 0.2804
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0098 0.5818 0.8758
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0073 0.3966 0.3933
Schistosoma mansoni hypothetical protein 0.0154 1 1
Trypanosoma cruzi multidrug resistance protein E, putative 0.0033 0.099 0.5669
Loa Loa (eye worm) hypothetical protein 0.0056 0.2634 0.518
Trypanosoma cruzi trans-sialidase, putative 0.0031 0.0775 0.4368
Entamoeba histolytica P-glycoprotein-2 0.0059 0.2859 0.7207
Echinococcus multilocularis short transient receptor potential channel 6 0.0058 0.2854 0.2815
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0059 0.2859 1
Schistosoma mansoni ATP-binding cassette sub-family B member 7 mitochondrial precursor (abc7) 0.0021 0.0054 0.0054
Loa Loa (eye worm) hypothetical protein 0.003 0.0726 0.1428
Brugia malayi hypothetical protein 0.0021 0.0054 0.0137
Plasmodium falciparum thioredoxin reductase 0.0043 0.1705 0.4402
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0071 0.3804 1
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0059 0.2859 0.2859
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0059 0.2859 1
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0109 0.6635 1
Echinococcus multilocularis geminin 0.0154 1 1
Echinococcus multilocularis short transient receptor potential channel 6 0.0058 0.2854 0.2815
Loa Loa (eye worm) ABC transporter transmembrane region family protein 0.0033 0.099 0.1947
Echinococcus granulosus thioredoxin glutathione reductase 0.0043 0.1705 0.1705
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0073 0.3966 0.3966
Schistosoma mansoni peptidase Clp (S14 family) 0.0071 0.3804 0.3804
Plasmodium vivax ubiquitin-conjugating enzyme E2 N, putative 0.004 0.151 0.3882
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0059 0.2859 0.2859
Loa Loa (eye worm) thioredoxin reductase 0.0043 0.1705 0.3353
Echinococcus granulosus multidrug resistance protein 1 0.0038 0.1353 0.1353
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0059 0.2859 1
Trypanosoma cruzi trans-sialidase, putative 0.0031 0.0775 0.4368
Echinococcus granulosus multidrug resistance associated protein 1 0.0033 0.099 0.099
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0025 0.0324 0.0719
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0059 0.2859 0.5622
Trypanosoma brucei multidrug resistance-associated protein, putative 0.0033 0.099 0.5669
Trypanosoma cruzi trans-sialidase, putative 0.0031 0.0776 0.437
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0025 0.0324 0.041
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0059 0.2859 0.7478
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0098 0.5818 0.8758
Entamoeba histolytica hypothetical protein 0.0073 0.3966 1
Trypanosoma brucei trans-sialidase, putative 0.0031 0.0776 0.437
Trichomonas vaginalis ABC transporter, putative 0.0059 0.2859 1
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0059 0.2859 0.7478
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0059 0.2859 1
Schistosoma mansoni transient receptor potential channel 0.0058 0.2854 0.2854
Entamoeba histolytica P-glyco protein 6, putative 0.0059 0.2859 0.7207
Trypanosoma cruzi trans-sialidase, putative 0.0031 0.0775 0.4368
Trichomonas vaginalis ABC transporter, putative 0.0059 0.2859 1
Brugia malayi multidrug resistance related protein 1 0.0033 0.099 0.2497
Brugia malayi ABC transporter family protein 0.0021 0.0054 0.0137
Trypanosoma brucei multidrug resistance protein E 0.0033 0.099 0.5669
Trypanosoma brucei p-glycoprotein 0.0033 0.099 0.5669
Trypanosoma brucei ubiquitin-protein ligase, putative 0.004 0.151 0.8819
Loa Loa (eye worm) glutathione reductase 0.0043 0.1705 0.3353
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0059 0.2859 1
Schistosoma mansoni transient receptor potential channel 0.0058 0.2854 0.2854
Plasmodium vivax glutathione reductase, putative 0.0043 0.1705 0.4402
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0033 0.099 0.2495
Plasmodium vivax thioredoxin reductase, putative 0.0043 0.1705 0.4402
Plasmodium vivax multidrug resistance protein 1, putative 0.0059 0.2859 0.7478
Loa Loa (eye worm) hypothetical protein 0.0071 0.3804 0.7482
Echinococcus multilocularis ATP binding cassette sub family B 0.0058 0.2804 0.2765
Trypanosoma brucei trans-sialidase, putative 0.0031 0.0776 0.437
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0098 0.5818 0.8758
Trypanosoma cruzi trans-sialidase, Group I, putative 0.0031 0.0776 0.437
Trypanosoma cruzi trans-sialidase, Group I, putative 0.0031 0.0776 0.437
Brugia malayi ubiquitin conjugating enzyme protein 13 0.004 0.151 0.3808
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0047 0.1975 0.2918
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.004 0.151 0.8819
Trichomonas vaginalis abcb9, putative 0.0059 0.2859 1
Entamoeba histolytica hypothetical protein 0.0073 0.3966 1
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0071 0.3804 1
Echinococcus multilocularis multidrug resistance protein 1 0.0038 0.1353 0.1306
Echinococcus granulosus multidrug resistance protein 1 0.0059 0.2859 0.2859
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0047 0.1975 0.2918
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.004 0.151 0.297
Brugia malayi multidrug resistance protein 3 0.0059 0.2859 0.7207
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0071 0.3804 1
Entamoeba histolytica ATP-binding cassette protein, putative 0.0033 0.099 0.2497
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0059 0.2859 0.282
Trypanosoma brucei trans-sialidase, putative 0.0031 0.0776 0.437
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0059 0.2859 1
Entamoeba histolytica P-glycoprotein-2, putative 0.0059 0.2859 0.7207
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0059 0.2859 0.282
Giardia lamblia Multidrug resistance-associated protein 1 0.0033 0.099 1
Trichomonas vaginalis abcb9, putative 0.0059 0.2859 1
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0059 0.2859 1
Schistosoma mansoni multidrug resistance protein 0.0059 0.2859 0.2859
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0025 0.0324 0.0719

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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