Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.005 | 0.2504 | 0.2172 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.005 | 0.2504 | 0.2869 |
Trypanosoma brucei | phosphatidylinositol 3-kinase, putative | 0.0018 | 0.0425 | 0.1697 |
Toxoplasma gondii | target of rapamycin (TOR), putative | 0.0018 | 0.0425 | 0.1697 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0018 | 0.0425 | 0.1697 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0018 | 0.0425 | 0.1697 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0018 | 0.0425 | 0.1697 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0062 | 0.3288 | 0.3766 |
Trypanosoma brucei | Phosphatidylinositol 3-kinase tor1 | 0.0018 | 0.0425 | 0.1697 |
Loa Loa (eye worm) | TAR-binding protein | 0.0062 | 0.3288 | 0.3766 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0062 | 0.3288 | 0.3447 |
Trypanosoma brucei | phosphatidylinositol 4-kinase, putative | 0.0018 | 0.0425 | 0.1697 |
Trypanosoma brucei | protein kinase, putative | 0.005 | 0.2504 | 1 |
Echinococcus multilocularis | tar DNA binding protein | 0.0062 | 0.3288 | 0.299 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.005 | 0.2504 | 1 |
Toxoplasma gondii | FATC domain-containing protein | 0.0024 | 0.0852 | 0.3404 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 1 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0018 | 0.0425 | 0.1697 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0018 | 0.0425 | 0.1697 |
Trypanosoma brucei | phosphatidylinositol 3-related kinase, putative | 0.0018 | 0.0425 | 0.1697 |
Schistosoma mansoni | serine/threonine protein kinase | 0.005 | 0.2504 | 0.2172 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0018 | 0.0425 | 0.1697 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0018 | 0.0425 | 0.1697 |
Trypanosoma cruzi | phosphatidylinositol kinase related protein, putative | 0.0021 | 0.0632 | 0.0997 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0018 | 0.0425 | 0.1697 |
Brugia malayi | TAR-binding protein | 0.0062 | 0.3288 | 0.3447 |
Trypanosoma brucei | phosphatidylinositol kinase related protein, putative | 0.0024 | 0.0852 | 0.3404 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0018 | 0.0425 | 0.1697 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0018 | 0.0425 | 0.1697 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0018 | 0.0425 | 0.1697 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.005 | 0.2504 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.0062 | 0.3288 | 0.3766 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0018 | 0.0425 | 0.1697 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0018 | 0.0425 | 0.1697 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0146 | 0.873 | 0.8674 |
Loa Loa (eye worm) | hypothetical protein | 0.0146 | 0.873 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0146 | 0.873 | 1 |
Brugia malayi | Muscleblind-like protein | 0.0146 | 0.873 | 1 |
Echinococcus multilocularis | muscleblind protein | 0.0146 | 0.873 | 0.8674 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.005 | 0.2504 | 1 |
Brugia malayi | RNA binding protein | 0.0062 | 0.3288 | 0.3447 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.005 | 0.2504 | 0.2172 |
Brugia malayi | MAP kinase sur-1 | 0.005 | 0.2504 | 0.2504 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0018 | 0.0425 | 0.1697 |
Trypanosoma cruzi | phosphatidylinositol kinase related protein, putative | 0.0024 | 0.0852 | 0.2055 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0018 | 0.0425 | 0.1697 |
Echinococcus granulosus | mitogen activated protein kinase | 0.005 | 0.2504 | 0.2172 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0024 | 0.0852 | 0.3404 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0018 | 0.0425 | 0.1697 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0018 | 0.0425 | 0.1697 |
Giardia lamblia | Kinase, CMGC MAPK | 0.005 | 0.2504 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0018 | 0.0425 | 0.1697 |
Schistosoma mansoni | ataxia telangiectasia mutated (atm) | 0.0024 | 0.0852 | 0.0446 |
Trypanosoma brucei | target of rapamycin kinase 3, putative | 0.0018 | 0.0425 | 0.1697 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0018 | 0.0425 | 0.1697 |
Entamoeba histolytica | hypothetical protein | 0.0024 | 0.0852 | 1 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.005 | 0.2504 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.3288 | 0.299 |
Trichomonas vaginalis | CMGC family protein kinase | 0.005 | 0.2504 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0018 | 0.0425 | 0.1697 |
Trichomonas vaginalis | CMGC family protein kinase | 0.005 | 0.2504 | 1 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.005 | 0.2504 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0018 | 0.0425 | 0.1697 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0018 | 0.0425 | 0.1697 |
Leishmania major | phosphatidylinositol kinase related protein, putative | 0.0018 | 0.0427 | 0.0011 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.3288 | 0.299 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.3288 | 0.299 |
Trichomonas vaginalis | CMGC family protein kinase | 0.005 | 0.2504 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0018 | 0.0425 | 0.1697 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.3288 | 0.299 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.3288 | 0.299 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0018 | 0.0425 | 0.1697 |
Trypanosoma cruzi | phosphatidylinositol kinase related protein, putative | 0.0018 | 0.0427 | 0.0011 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.005 | 0.2504 | 0.2172 |
Echinococcus granulosus | serine protein kinase ATM | 0.0024 | 0.0852 | 0.0446 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0018 | 0.0425 | 0.1697 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.005 | 0.2504 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0018 | 0.0425 | 0.1697 |
Echinococcus multilocularis | geminin | 0.0165 | 1 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0018 | 0.0425 | 0.1697 |
Trichomonas vaginalis | CMGC family protein kinase | 0.005 | 0.2504 | 1 |
Echinococcus granulosus | tar DNA binding protein | 0.0062 | 0.3288 | 0.299 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.005 | 0.2504 | 1 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0024 | 0.0852 | 0.0515 |
Echinococcus granulosus | muscleblind protein | 0.0146 | 0.873 | 0.8674 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0018 | 0.0425 | 0.0487 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0018 | 0.0425 | 0.1697 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0018 | 0.0425 | 0.1697 |
Echinococcus multilocularis | serine protein kinase ATM | 0.0024 | 0.0852 | 0.0446 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0632 | 0.0724 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 1 | 1 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0018 | 0.0425 | 0.0487 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.005 | 0.2504 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.