TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 341.351 | Formula: C13H11N9OS
H donors: 2 H acceptors: 7 LogP: 0.83 Rotable bonds: 3
Rule of 5 violations (Lipinski): 1
SMILES: Cc1cc(C)c2c(n1)nn1c2nnc(c1N)C(=O)Nc1nncs1
InChi: 1S/C13H11N9OS/c1-5-3-6(2)16-10-7(5)11-19-18-8(9(14)22(11)21-10)12(23)17-13-20-15-4-24-13/h3-4H,14H2,1-2H3,(H,17,20,23)
InChiKey: YDJTXMDNYLBDLF-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0017	0.0017
Trichomonas vaginalis	cyclin A, putative	0.0051	0.0272	0.0462
Mycobacterium ulcerans	dehydrogenase	0.0055	0.0338	0.5
Schistosoma mansoni	amine GPCR	0.0033	0.0017	0.0017
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0033	0.0017	0.0021
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0033	0.0017	0.0021
Leishmania major	UDP-galactopyranose mutase	0.0055	0.0338	1
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0017	0.0017
Loa Loa (eye worm)	hypothetical protein	0.0051	0.0272	0.0272
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0172	0.2015	0.3415
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0444	0.5899	1
Schistosoma mansoni	amine GPCR	0.0033	0.0017	0.0017
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0033	0.0017	0.0017
Trichomonas vaginalis	hypothetical protein	0.0141	0.1568	0.2658
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0033	0.0017	0.0017
Mycobacterium ulcerans	flavin-containing monoamine oxidase AofH	0.0055	0.0338	0.5
Brugia malayi	putative neuropeptide receptor NPR1	0.0033	0.0017	0.0017
Echinococcus granulosus	neuropeptide receptor A26	0.0033	0.0017	0.0017
Brugia malayi	Dopamine receptor	0.0033	0.0017	0.0017
Trichomonas vaginalis	conserved hypothetical protein	0.0141	0.1568	0.2658
Loa Loa (eye worm)	proprotein convertase 2	0.0172	0.2015	0.2015
Schistosoma mansoni	peptide (allatostatin)-like receptor	0.0033	0.0017	0.0017
Echinococcus granulosus	rhodopsin orphan GPCR	0.0033	0.0017	0.0017
Brugia malayi	larval opioid receptor	0.0033	0.0017	0.0017
Mycobacterium ulcerans	protoporphyrinogen oxidase	0.0055	0.0338	0.5
Brugia malayi	hypothetical protein	0.0033	0.0017	0.0017
Echinococcus granulosus	sex peptide receptor	0.0033	0.0017	0.0017
Schistosoma mansoni	subfamily S8B non-peptidase homologue (S08 family)	0.0172	0.2015	0.2015
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0017	0.0017
Loa Loa (eye worm)	endoprotease bli-4	0.073	1	1
Loa Loa (eye worm)	hypothetical protein	0.0051	0.0272	0.0272
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0033	0.0017	0.0017
Echinococcus granulosus	biogenic amine 5HT receptor	0.0033	0.0017	0.0017
Echinococcus granulosus	cyclin B	0.0051	0.0272	0.0272
Schistosoma mansoni	neuropeptide F-like receptor	0.0033	0.0017	0.0017
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0033	0.0017	0.0021
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0033	0.0017	0.0017
Trichomonas vaginalis	cyclins, putative	0.0051	0.0272	0.0462
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0017	0.0017
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0017	0.0017
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0033	0.0017	0.0017
Echinococcus multilocularis	g protein coupled receptor	0.0033	0.0017	0.0021
Schistosoma mansoni	neuropeptide receptor	0.0033	0.0017	0.0017
Echinococcus granulosus	rhodopsin orphan GPCR	0.0033	0.0017	0.0017
Echinococcus multilocularis		0.0055	0.0338	0.0423
Brugia malayi	sulfakinin receptor protein	0.0033	0.0017	0.0017
Echinococcus multilocularis	growth hormone secretagogue receptor type 1	0.0033	0.0017	0.0021
Trichomonas vaginalis	proprotein convertase subtilisin/kexin type, putative	0.0141	0.1568	0.2658
Brugia malayi	amine oxidase, flavin-containing family protein	0.0078	0.0667	0.0667
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0017	0.0017
Echinococcus multilocularis	cyclin B	0.0051	0.0272	0.0341
Loa Loa (eye worm)	hypothetical protein	0.0295	0.3772	0.3772
Trichomonas vaginalis	cyclins, putative	0.0051	0.0272	0.0462
Trichomonas vaginalis	conserved hypothetical protein	0.0141	0.1568	0.2658
Brugia malayi	hypothetical protein	0.0033	0.0017	0.0017
Schistosoma mansoni	furin-1 (S08 family)	0.0317	0.4093	0.4093
Echinococcus granulosus	growth hormone secretagogue receptor type 1	0.0033	0.0017	0.0017
Echinococcus multilocularis	sex peptide receptor	0.0033	0.0017	0.0021
Schistosoma mansoni	peptide (FMRFamide/neurokinin-3)-like receptor	0.0033	0.0017	0.0017
Onchocerca volvulus		0.0051	0.0272	0.068
Brugia malayi	proprotein convertase 2	0.0459	0.6115	0.6115
Schistosoma mansoni	hypothetical protein	0.0033	0.0017	0.0017
Echinococcus granulosus	orexin receptor type 2	0.0033	0.0017	0.0017
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0033	0.0017	0.0021
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0017	0.0017
Schistosoma mansoni	opsin-like receptor	0.0033	0.0017	0.0017
Echinococcus granulosus	proprotein convertase subtilisin:kexin type 5	0.0444	0.5899	0.5899
Schistosoma mansoni	amine GPCR	0.0033	0.0017	0.0017
Echinococcus granulosus	rhodopsin orphan GPCR	0.0033	0.0017	0.0017
Toxoplasma gondii	histone lysine-specific demethylase	0.0055	0.0338	0.5
Brugia malayi	hypothetical protein	0.0033	0.0017	0.0017
Echinococcus granulosus	G protein coupled 5 hydroxytryptamine receptor	0.0033	0.0017	0.0017
Brugia malayi	Dopamine receptor protein 1, putative (partial)	0.0033	0.0017	0.0017
Trichomonas vaginalis	conserved hypothetical protein	0.0141	0.1568	0.2658
Schistosoma mansoni	subfamily S8B unassigned peptidase (S08 family)	0.073	1	1
Chlamydia trachomatis	protoporphyrinogen oxidase	0.0055	0.0338	0.5
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0017	0.0017
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0017	0.0017
Loa Loa (eye worm)	G-protein coupled receptor	0.0033	0.0017	0.0017
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0017	0.0017
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0017	0.0017
Echinococcus granulosus	tm gpcr rhodopsin	0.0033	0.0017	0.0017
Schistosoma mansoni	biogenic amine receptor	0.0033	0.0017	0.0017
Schistosoma mansoni	biogenic amine receptor	0.0033	0.0017	0.0017
Schistosoma mansoni	hypothetical protein	0.0141	0.1568	0.1568
Echinococcus granulosus	tm gpcr rhodopsin	0.0033	0.0017	0.0017
Echinococcus multilocularis	G protein coupled receptor 139	0.0033	0.0017	0.0021
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0033	0.0017	0.0017
Loa Loa (eye worm)	hypothetical protein	0.0272	0.3442	0.3442
Trichomonas vaginalis	cyclin B, putative	0.0051	0.0272	0.0462
Brugia malayi	Myb-like DNA-binding domain containing protein	0.0169	0.1971	0.1971
Echinococcus multilocularis	orexin receptor type 2	0.0033	0.0017	0.0021
Echinococcus granulosus	rhodopsin orphan GPCR	0.0033	0.0017	0.0017
Echinococcus multilocularis	peptide (allatostatin:somatostatin)	0.0033	0.0017	0.0021
Echinococcus multilocularis	neuropeptide Y receptor	0.0033	0.0017	0.0021
Giardia lamblia	G2/mitotic-specific cyclin B	0.0051	0.0272	0.0794
Entamoeba histolytica	cyclin, putative	0.0051	0.0272	1
Brugia malayi	SWIRM domain containing protein	0.0295	0.3772	0.3772
Brugia malayi	neuroendocrine convertase 1 precursor	0.0459	0.6115	0.6115
Plasmodium falciparum	protoporphyrinogen oxidase	0.0055	0.0338	1
Plasmodium vivax	hypothetical protein, conserved	0.0055	0.0338	0.5
Echinococcus multilocularis	thyrotropin releasing hormone receptor	0.0033	0.0017	0.0021
Echinococcus multilocularis	neuropeptides capa receptor	0.0033	0.0017	0.0021
Schistosoma mansoni	amine oxidase	0.0055	0.0338	0.0338
Trichomonas vaginalis	conserved hypothetical protein	0.0141	0.1568	0.2658
Schistosoma mansoni	alpha-1 adrenergic receptor	0.0033	0.0017	0.0017
Echinococcus granulosus	lysine specific histone demethylase 1A	0.0055	0.0338	0.0338
Brugia malayi	hypothetical protein	0.0033	0.0017	0.0017
Schistosoma mansoni	neuropeptide F-like receptor	0.0033	0.0017	0.0017
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0017	0.0017
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0033	0.0017	0.0017
Echinococcus granulosus	hypothetical protein	0.0033	0.0017	0.0017
Brugia malayi	Cyclin, N-terminal domain containing protein	0.0051	0.0272	0.0272
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0017	0.0017
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0033	0.0017	0.0021
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0338	0.0338
Schistosoma mansoni	Lysine-specific histone demethylase 1	0.0272	0.3442	0.3442
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0017	0.0017
Brugia malayi	hypothetical protein	0.0033	0.0017	0.0017
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0017	0.0017
Echinococcus multilocularis	neuropeptides capa receptor	0.0033	0.0017	0.0021
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0033	0.0017	0.0017
Echinococcus multilocularis	somatostatin receptor	0.0033	0.0017	0.0021
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0017	0.0017
Echinococcus multilocularis	neuropeptide receptor	0.0033	0.0017	0.0021
Schistosoma mansoni	thyrotropin-releasing hormone receptor	0.0033	0.0017	0.0017
Echinococcus multilocularis	neuroendocrine convertase 2	0.0459	0.6115	0.7665
Trichomonas vaginalis	conserved hypothetical protein	0.0141	0.1568	0.2658
Schistosoma mansoni	growth hormone secretagogue receptor	0.0033	0.0017	0.0017
Echinococcus granulosus	g protein coupled receptor	0.0033	0.0017	0.0017
Plasmodium falciparum	lysine-specific histone demethylase 1, putative	0.0055	0.0338	1
Brugia malayi	hypothetical protein	0.0033	0.0017	0.0017
Brugia malayi	Dopamine receptor protein 1	0.0033	0.0017	0.0017
Echinococcus multilocularis	neuropeptide receptor	0.0033	0.0017	0.0021
Echinococcus granulosus	Furin 1	0.0172	0.2015	0.2015
Echinococcus granulosus	neuropeptide FF receptor 2	0.0033	0.0017	0.0017
Echinococcus granulosus	g protein coupled receptor	0.0033	0.0017	0.0017
Echinococcus multilocularis	neuropeptide FF receptor 2	0.0033	0.0017	0.0021
Schistosoma mansoni	neuropeptide receptor	0.0033	0.0017	0.0017
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0033	0.0017	0.0017
Brugia malayi	neuropeptide F receptor	0.0033	0.0017	0.0017
Schistosoma mansoni	biogenic amine receptor	0.0033	0.0017	0.0017
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0017	0.0017
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0033	0.0017	0.0017
Echinococcus multilocularis	G-protein coupled receptor, putative	0.0033	0.0017	0.0021
Echinococcus granulosus	neuropeptide Y receptor	0.0033	0.0017	0.0017
Trichomonas vaginalis	cyclins, putative	0.0051	0.0272	0.0462
Loa Loa (eye worm)	melatonin receptor type 1A	0.0033	0.0017	0.0017
Brugia malayi	hypothetical protein	0.0033	0.0017	0.0017
Brugia malayi	neuropeptide F receptor	0.0033	0.0017	0.0017
Trichomonas vaginalis	cyclin B, putative	0.0051	0.0272	0.0462
Brugia malayi	G-protein-linked acetylcholine receptor protein 2, putative	0.0033	0.0017	0.0017
Echinococcus multilocularis	neuropeptide Y receptor	0.0033	0.0017	0.0021
Echinococcus multilocularis	lysine specific histone demethylase 1A	0.0272	0.3442	0.4315
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0033	0.0017	0.0017
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0017	0.0017
Echinococcus multilocularis	tachykinin peptides receptor 99D	0.0033	0.0017	0.0021
Brugia malayi	hypothetical protein	0.0033	0.0017	0.0017
Schistosoma mansoni	biogenic amine (octopamine/dopamine) receptor	0.0033	0.0017	0.0017
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0017	0.0017
Echinococcus granulosus	neuropeptide receptor	0.0033	0.0017	0.0017
Trichomonas vaginalis	conserved hypothetical protein	0.0141	0.1568	0.2658
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0033	0.0017	0.0017
Echinococcus multilocularis	fmrfamide receptor	0.0033	0.0017	0.0021
Loa Loa (eye worm)	hypothetical protein	0.073	1	1
Plasmodium vivax	protoporphyrinogen oxidase, putative	0.0055	0.0338	0.5
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0017	0.0017
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0017	0.0017
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0033	0.0017	0.0021
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0033	0.0017	0.0021
Trichomonas vaginalis	leucine-rich repeat protein, BspA family	0.0141	0.1568	0.2658
Schistosoma mansoni	ancient conserved domain protein 2 (cyclin m2)	0.0033	0.0017	0.0017
Schistosoma mansoni	muscarinic acetylcholine (GAR) receptor	0.0033	0.0017	0.0017
Trichomonas vaginalis	cyclin B, putative	0.0051	0.0272	0.0462
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0017	0.0017
Echinococcus multilocularis	neuropeptide receptor A26	0.0033	0.0017	0.0021
Echinococcus granulosus	neuropeptide receptor	0.0033	0.0017	0.0017
Loa Loa (eye worm)	G-protein coupled receptor	0.0033	0.0017	0.0017
Echinococcus granulosus	peptide allatostatin:somatostatin	0.0033	0.0017	0.0017
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0017	0.0017
Echinococcus multilocularis	serotonin receptor	0.0033	0.0017	0.0021
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0033	0.0017	0.0021
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0172	0.2015	0.3415
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0033	0.0017	0.0021
Schistosoma mansoni	adenoreceptor	0.0033	0.0017	0.0017
Trichomonas vaginalis	conserved hypothetical protein	0.0141	0.1568	0.2658
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0017	0.0017
Trichomonas vaginalis	cyclin B, putative	0.0051	0.0272	0.0462
Schistosoma mansoni	amine oxidase	0.0055	0.0338	0.0338
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0033	0.0017	0.0017
Loa Loa (eye worm)	neuropeptide F receptor	0.0033	0.0017	0.0017
Schistosoma mansoni	myosin xvIII	0.0033	0.0017	0.0017
Loa Loa (eye worm)	5-hydroxytryptamine 2C receptor	0.0033	0.0017	0.0017
Echinococcus granulosus	thyrotropin releasing hormone receptor	0.0033	0.0017	0.0017
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0444	0.5899	1
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0172	0.2015	0.3415
Schistosoma mansoni	neuropeptide receptor	0.0033	0.0017	0.0017
Loa Loa (eye worm)	neuropeptide F receptor	0.0033	0.0017	0.0017
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0017	0.0017
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0017	0.0017
Mycobacterium leprae	PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO)	0.0055	0.0338	0.5
Echinococcus granulosus	7TM GPCR rhodopsin	0.0033	0.0017	0.0017
Brugia malayi	celfurPC protein	0.0589	0.7978	0.7978
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0017	0.0017
Brugia malayi	AKH receptor	0.0033	0.0017	0.0017
Brugia malayi	G-protein coupled receptor	0.0033	0.0017	0.0017
Echinococcus granulosus	7tm_1 domain containing protein	0.0033	0.0017	0.0017
Echinococcus multilocularis	dro:myosuppressin receptor	0.0033	0.0017	0.0021
Brugia malayi	G-protein coupled receptor	0.0033	0.0017	0.0017
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0017	0.0017
Schistosoma mansoni	amine GPCR	0.0033	0.0017	0.0017
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0017	0.0017
Echinococcus granulosus	neuropeptides capa receptor	0.0033	0.0017	0.0017
Trypanosoma brucei	mitotic cyclin 6	0.0051	0.0272	0.5
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0033	0.0017	0.0017
Schistosoma mansoni	neuropeptide f receptor 76f	0.0033	0.0017	0.0017
Echinococcus multilocularis	biogenic amine (5HT) receptor	0.0033	0.0017	0.0021
Echinococcus multilocularis	G protein coupled 5 hydroxytryptamine receptor	0.0033	0.0017	0.0021
Brugia malayi	Serotonin/octopamine receptor family protein 7	0.0033	0.0017	0.0017
Echinococcus multilocularis	neuropeptide s receptor	0.0033	0.0017	0.0021
Brugia malayi	follicle stimulating hormone receptor	0.0033	0.0017	0.0017
Schistosoma mansoni	hypothetical protein	0.0033	0.0017	0.0017
Echinococcus multilocularis	allatostatin A receptor	0.0033	0.0017	0.0021
Trypanosoma cruzi	UDP-galactopyranose mutase	0.0055	0.0338	1
Loa Loa (eye worm)	unidentified vitellogenin-linked transcript protein 6	0.0033	0.0017	0.0017
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0017	0.0017
Echinococcus granulosus	rhodopsin orphan GPCR	0.0033	0.0017	0.0017
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0033	0.0017	0.0021
Schistosoma mansoni	histamine-responsive GPCR (AAF21638)	0.0033	0.0017	0.0017
Schistosoma mansoni	neuropeptide receptor	0.0033	0.0017	0.0017
Echinococcus granulosus	somatostatin receptor	0.0033	0.0017	0.0017
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0017	0.0017
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0017	0.0017
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0033	0.0017	0.0017
Plasmodium vivax	lysine-specific histone demethylase 1, putative	0.0055	0.0338	0.5
Echinococcus granulosus	alpha 1A adrenergic receptor	0.0033	0.0017	0.0017
Trichomonas vaginalis	neuroendocrine convertase 2 precursor, putative	0.0141	0.1568	0.2658
Trypanosoma cruzi	UDP-galactopyranose mutase	0.0055	0.0338	1
Echinococcus granulosus	serotonin receptor	0.0033	0.0017	0.0017
Echinococcus granulosus	tachykinin peptides receptor 99D	0.0033	0.0017	0.0017
Schistosoma mansoni	hypothetical protein	0.0033	0.0017	0.0017
Brugia malayi	Melatonin receptor type 1A	0.0033	0.0017	0.0017
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0017	0.0017
Echinococcus multilocularis	protoporphyrinogen oxidase	0.0055	0.0338	0.0423
Echinococcus multilocularis	alpha 1A adrenergic receptor	0.0033	0.0017	0.0021
Echinococcus multilocularis	pyroglutamylated rfamide peptide receptor	0.0033	0.0017	0.0021
Brugia malayi	hypothetical protein	0.0033	0.0017	0.0017
Schistosoma mansoni	opsin-like receptor	0.0033	0.0017	0.0017
Echinococcus granulosus	rhodopsin orphan GPCR	0.0033	0.0017	0.0017
Trichomonas vaginalis	conserved hypothetical protein	0.0141	0.1568	0.2658
Plasmodium falciparum	conserved Plasmodium protein, unknown function	0.0055	0.0338	1
Toxoplasma gondii	histone lysine-specific demethylase LSD1/BHC110/KDMA1A	0.0055	0.0338	0.5
Brugia malayi	Dopamine receptor protein 2	0.0033	0.0017	0.0017
Trichomonas vaginalis	conserved hypothetical protein	0.0141	0.1568	0.2658
Echinococcus granulosus	g-protein coupled receptor	0.0033	0.0017	0.0017
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0172	0.2015	0.3415
Echinococcus multilocularis	proprotein convertase subtilisin:kexin type 5	0.0444	0.5899	0.7395
Brugia malayi	Tachykinin-like peptides receptor 99D	0.0033	0.0017	0.0017
Echinococcus multilocularis	g protein coupled receptor	0.0033	0.0017	0.0021
Schistosoma mansoni	Protoporphyrinogen oxidase chloroplast/mitochondrial precursor	0.0055	0.0338	0.0338
Echinococcus multilocularis	7TM GPCR, rhodopsin	0.0033	0.0017	0.0021
Echinococcus granulosus	lysine specific histone demethylase 1A	0.0272	0.3442	0.3442
Echinococcus multilocularis	Furin 1	0.0172	0.2015	0.2525
Brugia malayi	Cyclin, N-terminal domain containing protein	0.0051	0.0272	0.0272
Brugia malayi	hypothetical protein	0.0055	0.0338	0.0338
Echinococcus granulosus	neuropeptide Y receptor	0.0033	0.0017	0.0017
Brugia malayi	Serotonin receptor	0.0033	0.0017	0.0017
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0017	0.0017
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0017	0.0017
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0033	0.0017	0.0017
Schistosoma mansoni	opsin-like receptor	0.0033	0.0017	0.0017
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0338	0.0338
Brugia malayi	GnHR receptor homolog	0.0033	0.0017	0.0017
Brugia malayi	G protein-coupled receptor F59B2.13	0.0033	0.0017	0.0017
Brugia malayi	Serotonin receptor	0.0033	0.0017	0.0017
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0017	0.0017
Echinococcus multilocularis	g-protein coupled receptor	0.0033	0.0017	0.0021
Mycobacterium tuberculosis	Possible oxidoreductase	0.0055	0.0338	0.5
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0017	0.0017
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0017	0.0017
Brugia malayi	ORL1-like opioid receptor	0.0033	0.0017	0.0017
Trichomonas vaginalis	conserved hypothetical protein	0.0141	0.1568	0.2658
Echinococcus granulosus	fmrfamide receptor	0.0033	0.0017	0.0017
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0033	0.0017	0.0021
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0172	0.2015	0.3415
Loa Loa (eye worm)	G-protein-linked acetylcholine receptor protein 2	0.0033	0.0017	0.0017
Brugia malayi	G protein-coupled receptor	0.0033	0.0017	0.0017
Trichomonas vaginalis	conserved hypothetical protein	0.0141	0.1568	0.2658
Giardia lamblia	Furin precursor putative serine protease	0.0141	0.1568	0.4571
Plasmodium vivax	hypothetical protein, conserved	0.0055	0.0338	0.5
Schistosoma mansoni	hypothetical protein	0.0033	0.0017	0.0017
Brugia malayi	hypothetical protein	0.0033	0.0017	0.0017
Onchocerca volvulus	CoRest homolog	0.0174	0.2042	0.5393
Echinococcus granulosus	dro:myosuppressin receptor	0.0033	0.0017	0.0017
Loa Loa (eye worm)	hypothetical protein	0.0174	0.2042	0.2042
Echinococcus granulosus	allatostatin A receptor	0.0033	0.0017	0.0017
Mycobacterium ulcerans	monoamine oxidase	0.0055	0.0338	0.5
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0017	0.0017
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0033	0.0017	0.0021
Mycobacterium tuberculosis	Conserved hypothetical protein	0.0055	0.0338	0.5
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0017	0.0017
Brugia malayi	putative neuropeptide receptor	0.0033	0.0017	0.0017
Onchocerca volvulus		0.0295	0.3772	1
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0017	0.0017
Loa Loa (eye worm)	follicle stimulating hormone receptor	0.0033	0.0017	0.0017
Loa Loa (eye worm)	TYRA-2 protein	0.0033	0.0017	0.0017
Brugia malayi	Unidentified vitellogenin-linked transcript protein 6, putative	0.0033	0.0017	0.0017
Echinococcus granulosus	neuropeptides capa receptor	0.0033	0.0017	0.0017
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0033	0.0017	0.0017
Echinococcus granulosus	tm gpcr rhodopsin	0.0033	0.0017	0.0017
Schistosoma mansoni	histamine h1 receptor	0.0033	0.0017	0.0017
Loa Loa (eye worm)	hypothetical protein	0.0169	0.1971	0.1971
Echinococcus granulosus	g protein coupled receptor	0.0033	0.0017	0.0017
Echinococcus granulosus	rhodopsin orphan GPCR	0.0033	0.0017	0.0017
Brugia malayi	RE15519p	0.0033	0.0017	0.0017
Mycobacterium ulcerans	flavin-containing monoamine oxidase AofH	0.0055	0.0338	0.5
Loa Loa (eye worm)	hypothetical protein	0.0286	0.3646	0.3646
Echinococcus granulosus	pyroglutamylated rfamide peptide receptor	0.0033	0.0017	0.0017
Schistosoma mansoni	cyclin B	0.0051	0.0272	0.0272
Mycobacterium ulcerans	oxidoreductase	0.0055	0.0338	0.5
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0017	0.0017
Trichomonas vaginalis	cyclins, putative	0.0051	0.0272	0.0462
Echinococcus granulosus	biogenic amine 5HT receptor	0.0033	0.0017	0.0017
Loa Loa (eye worm)	hypothetical protein	0.0272	0.3442	0.3442
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0017	0.0017
Echinococcus multilocularis	g protein coupled receptor	0.0033	0.0017	0.0021
Echinococcus multilocularis	fmrfamide receptor	0.0033	0.0017	0.0021
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0033	0.0017	0.0021
Giardia lamblia	High cysteine membrane protein Group 2	0.0271	0.343	1
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0172	0.2015	0.3415
Loa Loa (eye worm)	hypothetical protein	0.0078	0.0667	0.0667
Echinococcus multilocularis	serotonin receptor	0.0033	0.0017	0.0021
Schistosoma mansoni	peptide (allatostatin/somatostatin)-like receptor	0.0033	0.0017	0.0017
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0017	0.0017
Brugia malayi	gonadotropin-releasing hormone receptor 2	0.0033	0.0017	0.0017
Loa Loa (eye worm)	gonadotropin-releasing hormone receptor 2	0.0033	0.0017	0.0017
Echinococcus granulosus	neuroendocrine convertase 2	0.0459	0.6115	0.6115
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0017	0.0017
Echinococcus granulosus	neuropeptide s receptor	0.0033	0.0017	0.0017
Echinococcus multilocularis		0.0589	0.7978	1
Echinococcus granulosus	G protein coupled receptor 139	0.0033	0.0017	0.0017
Schistosoma mansoni	amine GPCR	0.0033	0.0017	0.0017
Echinococcus granulosus	furin	0.073	1	1
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0033	0.0017	0.0017

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

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External resources for this compound

ChEMBL: CHEMBL2295978

Bibliographic References

No literature references available for this target.

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Detailed information for compound 1807907