Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | phosphatidylinositol 3-related kinase, putative | 0.0018 | 0.0425 | 0.1697 |
Echinococcus granulosus | mitogen activated protein kinase | 0.005 | 0.2504 | 0.2172 |
Schistosoma mansoni | serine/threonine protein kinase | 0.005 | 0.2504 | 0.2172 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0018 | 0.0425 | 0.1697 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0018 | 0.0425 | 0.1697 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.005 | 0.2504 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0018 | 0.0425 | 0.1697 |
Echinococcus multilocularis | muscleblind protein | 0.0146 | 0.873 | 0.8674 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0018 | 0.0425 | 0.1697 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0018 | 0.0425 | 0.1697 |
Loa Loa (eye worm) | TAR-binding protein | 0.0062 | 0.3288 | 0.3766 |
Loa Loa (eye worm) | hypothetical protein | 0.0146 | 0.873 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0018 | 0.0425 | 0.1697 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0018 | 0.0425 | 0.1697 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0062 | 0.3288 | 0.3766 |
Echinococcus multilocularis | serine protein kinase ATM | 0.0024 | 0.0852 | 0.0446 |
Trypanosoma brucei | phosphatidylinositol 3-kinase, putative | 0.0018 | 0.0425 | 0.1697 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0018 | 0.0425 | 0.1697 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0024 | 0.0852 | 0.3404 |
Echinococcus granulosus | tar DNA binding protein | 0.0062 | 0.3288 | 0.299 |
Trypanosoma brucei | target of rapamycin kinase 3, putative | 0.0018 | 0.0425 | 0.1697 |
Trypanosoma brucei | phosphatidylinositol 4-kinase, putative | 0.0018 | 0.0425 | 0.1697 |
Trypanosoma brucei | phosphatidylinositol kinase related protein, putative | 0.0024 | 0.0852 | 0.3404 |
Trypanosoma cruzi | phosphatidylinositol kinase related protein, putative | 0.0018 | 0.0427 | 0.0011 |
Trypanosoma brucei | Phosphatidylinositol 3-kinase tor1 | 0.0018 | 0.0425 | 0.1697 |
Brugia malayi | TAR-binding protein | 0.0062 | 0.3288 | 0.3447 |
Trypanosoma brucei | protein kinase, putative | 0.005 | 0.2504 | 1 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.005 | 0.2504 | 0.2172 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0018 | 0.0425 | 0.1697 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0632 | 0.0724 |
Toxoplasma gondii | FATC domain-containing protein | 0.0024 | 0.0852 | 0.3404 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0018 | 0.0425 | 0.1697 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0024 | 0.0852 | 0.0515 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.005 | 0.2504 | 0.2172 |
Brugia malayi | RNA binding protein | 0.0062 | 0.3288 | 0.3447 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0018 | 0.0425 | 0.0487 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0018 | 0.0425 | 0.1697 |
Trichomonas vaginalis | CMGC family protein kinase | 0.005 | 0.2504 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0018 | 0.0425 | 0.1697 |
Echinococcus granulosus | muscleblind protein | 0.0146 | 0.873 | 0.8674 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.005 | 0.2504 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0018 | 0.0425 | 0.1697 |
Schistosoma mansoni | ataxia telangiectasia mutated (atm) | 0.0024 | 0.0852 | 0.0446 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.3288 | 0.299 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.005 | 0.2504 | 0.2172 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0018 | 0.0425 | 0.1697 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0018 | 0.0425 | 0.1697 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.005 | 0.2504 | 1 |
Trypanosoma cruzi | phosphatidylinositol kinase related protein, putative | 0.0024 | 0.0852 | 0.2055 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0018 | 0.0425 | 0.0487 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0018 | 0.0425 | 0.1697 |
Echinococcus multilocularis | geminin | 0.0165 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 1 | 1 |
Brugia malayi | Muscleblind-like protein | 0.0146 | 0.873 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.0062 | 0.3288 | 0.3766 |
Toxoplasma gondii | target of rapamycin (TOR), putative | 0.0018 | 0.0425 | 0.1697 |
Echinococcus granulosus | serine protein kinase ATM | 0.0024 | 0.0852 | 0.0446 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.005 | 0.2504 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0018 | 0.0425 | 0.1697 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0018 | 0.0425 | 0.1697 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0018 | 0.0425 | 0.1697 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.005 | 0.2504 | 1 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.005 | 0.2504 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0018 | 0.0425 | 0.1697 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0018 | 0.0425 | 0.1697 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.3288 | 0.299 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0146 | 0.873 | 0.8674 |
Giardia lamblia | Kinase, CMGC MAPK | 0.005 | 0.2504 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.005 | 0.2504 | 1 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.005 | 0.2504 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.3288 | 0.299 |
Brugia malayi | MAP kinase sur-1 | 0.005 | 0.2504 | 0.2504 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.3288 | 0.299 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0018 | 0.0425 | 0.1697 |
Trypanosoma cruzi | phosphatidylinositol kinase related protein, putative | 0.0021 | 0.0632 | 0.0997 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0018 | 0.0425 | 0.1697 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.3288 | 0.299 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0018 | 0.0425 | 0.1697 |
Leishmania major | phosphatidylinositol kinase related protein, putative | 0.0018 | 0.0427 | 0.0011 |
Echinococcus multilocularis | tar DNA binding protein | 0.0062 | 0.3288 | 0.299 |
Trichomonas vaginalis | CMGC family protein kinase | 0.005 | 0.2504 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0018 | 0.0425 | 0.1697 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.005 | 0.2504 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0146 | 0.873 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0018 | 0.0425 | 0.1697 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0062 | 0.3288 | 0.3447 |
Entamoeba histolytica | hypothetical protein | 0.0024 | 0.0852 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.005 | 0.2504 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0018 | 0.0425 | 0.1697 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0018 | 0.0425 | 0.1697 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0018 | 0.0425 | 0.1697 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 1 | 1 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.005 | 0.2504 | 0.2869 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.