Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | epidermal growth factor receptor | 0.025 | 0.3692 | 0.32 |
Trypanosoma cruzi | fructose-1,6-bisphosphatase, cytosolic, putative | 0.0333 | 0.6135 | 1 |
Leishmania major | 0.0333 | 0.6135 | 0.5 | |
Echinococcus multilocularis | insulin receptor | 0.0148 | 0.0724 | 0.0145 |
Trypanosoma cruzi | fructose-1,6-bisphosphatase, cytosolic, putative | 0.0333 | 0.6135 | 1 |
Echinococcus granulosus | epidermal growth factor receptor | 0.0464 | 1 | 1 |
Toxoplasma gondii | fructose-bisphospatase II | 0.0333 | 0.6135 | 1 |
Echinococcus multilocularis | insulin growth factor 1 receptor beta | 0.0148 | 0.0724 | 0.0145 |
Brugia malayi | fructose-1,6-bisphosphatase | 0.0333 | 0.6135 | 0.5834 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.025 | 0.3692 | 0.3299 |
Schistosoma mansoni | tyrosine kinase | 0.025 | 0.3692 | 0.32 |
Schistosoma mansoni | tyrosine kinase | 0.0247 | 0.3615 | 0.3117 |
Trypanosoma brucei | fructose-1,6-bisphosphatase | 0.0333 | 0.6135 | 1 |
Schistosoma mansoni | tyrosine kinase | 0.025 | 0.3692 | 0.32 |
Schistosoma mansoni | tyrosine kinase | 0.0247 | 0.3615 | 0.3117 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.0464 | 1 | 1 |
Schistosoma mansoni | fructose-16-bisphosphatase-related | 0.0333 | 0.6135 | 0.5834 |
Echinococcus multilocularis | fructose 1,6 bisphosphatase 1 | 0.0333 | 0.6135 | 0.5894 |
Echinococcus granulosus | melanoma receptor tyrosine protein kinase | 0.025 | 0.3692 | 0.32 |
Echinococcus granulosus | fructose 16 bisphosphatase 1 | 0.0333 | 0.6135 | 0.5834 |
Loa Loa (eye worm) | fructose-1,6-bisphosphatase | 0.0333 | 0.6135 | 0.5834 |
Schistosoma mansoni | tyrosine kinase | 0.0464 | 1 | 1 |
Loa Loa (eye worm) | TK/EGFR protein kinase | 0.0464 | 1 | 1 |
Schistosoma mansoni | tyrosine kinase | 0.0247 | 0.3615 | 0.3117 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.