Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0128 | 0.1368 | 0.1289 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0035 | 0.009 | 0.5 |
Schistosoma mansoni | gliotactin | 0.0128 | 0.1368 | 0.1289 |
Brugia malayi | Carboxylesterase family protein | 0.0128 | 0.1368 | 0.1289 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0035 | 0.009 | 0.5 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0757 | 1 | 1 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0372 | 0.4712 | 0.4664 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0128 | 0.1368 | 0.1289 |
Brugia malayi | Carboxylesterase family protein | 0.0128 | 0.1368 | 0.1289 |
Loa Loa (eye worm) | hypothetical protein | 0.0757 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0128 | 0.1368 | 0.1289 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0757 | 1 | 1 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0757 | 1 | 1 |
Leishmania major | importin beta-1 subunit, putative | 0.0028 | 0 | 0.5 |
Onchocerca volvulus | 0.0128 | 0.1368 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0128 | 0.1368 | 0.1289 |
Loa Loa (eye worm) | hypothetical protein | 0.0128 | 0.1368 | 0.1289 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0128 | 0.1368 | 0.5 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0128 | 0.1368 | 0.1289 |
Brugia malayi | Carboxylesterase family protein | 0.0757 | 1 | 1 |
Echinococcus multilocularis | neuroligin | 0.0128 | 0.1368 | 0.1289 |
Loa Loa (eye worm) | hypothetical protein | 0.0757 | 1 | 1 |
Plasmodium falciparum | importin beta, putative | 0.0035 | 0.009 | 0.5 |
Onchocerca volvulus | 0.0128 | 0.1368 | 0.5 | |
Echinococcus multilocularis | snurportin 1 | 0.0372 | 0.4712 | 0.4664 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0128 | 0.1368 | 0.5 |
Onchocerca volvulus | 0.0128 | 0.1368 | 0.5 | |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0128 | 0.1368 | 0.5 |
Loa Loa (eye worm) | carboxylesterase | 0.0757 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0128 | 0.1368 | 0.1289 |
Echinococcus granulosus | neuroligin | 0.0128 | 0.1368 | 0.1289 |
Loa Loa (eye worm) | carboxylesterase | 0.0128 | 0.1368 | 0.1289 |
Brugia malayi | Carboxylesterase family protein | 0.0128 | 0.1368 | 0.1289 |
Brugia malayi | hypothetical protein | 0.0128 | 0.1368 | 0.1289 |
Loa Loa (eye worm) | hypothetical protein | 0.0128 | 0.1368 | 0.1289 |
Echinococcus granulosus | carboxylesterase 5A | 0.0757 | 1 | 1 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0128 | 0.1368 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0128 | 0.1368 | 0.1289 |
Brugia malayi | RNA, U transporter 1 | 0.0099 | 0.0971 | 0.0889 |
Entamoeba histolytica | hypothetical protein | 0.0028 | 0 | 0.5 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0128 | 0.1368 | 0.1289 |
Loa Loa (eye worm) | carboxylesterase | 0.0128 | 0.1368 | 0.1289 |
Echinococcus granulosus | acetylcholinesterase | 0.0757 | 1 | 1 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0128 | 0.1368 | 0.1289 |
Loa Loa (eye worm) | hypothetical protein | 0.0128 | 0.1368 | 0.1289 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0128 | 0.1368 | 0.5 |
Echinococcus multilocularis | acetylcholinesterase | 0.0757 | 1 | 1 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.0035 | 0.009 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0128 | 0.1368 | 0.1289 |
Echinococcus granulosus | acetylcholinesterase | 0.0757 | 1 | 1 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0128 | 0.1368 | 0.1289 |
Schistosoma mansoni | hypothetical protein | 0.0372 | 0.4712 | 0.4664 |
Loa Loa (eye worm) | hypothetical protein | 0.0128 | 0.1368 | 0.1289 |
Plasmodium vivax | importin-beta 2, putative | 0.0035 | 0.009 | 0.5 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0128 | 0.1368 | 0.1289 |
Schistosoma mansoni | acetylcholinesterase | 0.0128 | 0.1368 | 0.1289 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0128 | 0.1368 | 0.1289 |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.0028 | 0 | 0.5 |
Echinococcus granulosus | snurportin 1 | 0.0372 | 0.4712 | 0.4664 |
Onchocerca volvulus | 0.0128 | 0.1368 | 0.5 | |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0128 | 0.1368 | 0.1289 |
Onchocerca volvulus | 0.0128 | 0.1368 | 0.5 | |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0128 | 0.1368 | 0.1289 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0128 | 0.1368 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0757 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.