Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0288 | 0.0108 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0035 | 0.1812 | 0.526 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0028 | 0.1411 | 0.1252 |
Brugia malayi | intermediate filament protein | 0.0058 | 0.3192 | 1 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0.0144 | 0.5 |
Echinococcus granulosus | GPCR family 2 | 0.0016 | 0.0705 | 0.0532 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0144 | 0.5 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0144 | 0.5 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0051 | 0.2766 | 0.8538 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.1812 | 0.1812 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0288 | 0.0108 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0031 | 0.1594 | 0.4498 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0705 | 0.0705 |
Echinococcus multilocularis | GPCR, family 2 | 0.0016 | 0.0705 | 0.0532 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0058 | 0.3192 | 1 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0007 | 0.0182 | 0.0182 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.0705 | 0.0532 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0051 | 0.2766 | 0.8534 |
Echinococcus multilocularis | cpg binding protein | 0.0031 | 0.1587 | 0.1431 |
Onchocerca volvulus | 0.0058 | 0.3192 | 1 | |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.1587 | 0.1587 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0144 | 0.5 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.0705 | 0.0532 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.1348 | 0.3651 |
Echinococcus multilocularis | geminin | 0.0172 | 1 | 1 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.0705 | 0.0532 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0144 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0705 | 0.1435 |
Brugia malayi | CXXC zinc finger family protein | 0.0029 | 0.1488 | 0.4146 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0016 | 0.0705 | 0.1455 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0705 | 0.0705 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.1411 | 0.3868 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0058 | 0.3192 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0144 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.1348 | 0.3651 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0705 | 0.0705 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0.0144 | 0.5 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0031 | 0.1594 | 0.4511 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.3192 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1812 | 0.5248 |
Schistosoma mansoni | hypothetical protein | 0.0172 | 1 | 1 |
Echinococcus multilocularis | lamin dm0 | 0.0058 | 0.3192 | 0.3065 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0144 | 0.5 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0051 | 0.2766 | 0.8538 |
Echinococcus multilocularis | musashi | 0.0058 | 0.3192 | 0.3065 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0144 | 0.5 |
Echinococcus multilocularis | lamin | 0.0058 | 0.3192 | 0.3065 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0028 | 0.1411 | 0.1252 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0016 | 0.0705 | 0.1435 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.3129 | 0.9783 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.1488 | 0.1488 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0144 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0172 | 1 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0144 | 0.5 |
Echinococcus granulosus | lamin dm0 | 0.0058 | 0.3192 | 0.3065 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0144 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0144 | 0.5 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0055 | 0.3042 | 0.5 |
Echinococcus granulosus | intermediate filament protein | 0.0058 | 0.3192 | 0.3065 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.1587 | 0.1587 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2766 | 0.8534 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0144 | 0.5 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0016 | 0.0705 | 0.1455 |
Schistosoma mansoni | lamin | 0.0058 | 0.3192 | 0.3192 |
Onchocerca volvulus | 0.0058 | 0.3192 | 1 | |
Schistosoma mansoni | lamin | 0.0058 | 0.3192 | 0.3192 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0062 | 0.3435 | 0.3435 |
Loa Loa (eye worm) | intermediate filament protein | 0.0058 | 0.3192 | 1 |
Echinococcus granulosus | lamin | 0.0058 | 0.3192 | 0.3065 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0029 | 0.1488 | 0.4132 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0144 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0705 | 0.0705 |
Schistosoma mansoni | intermediate filament proteins | 0.0058 | 0.3192 | 0.3192 |
Trichomonas vaginalis | helicase, putative | 0.0007 | 0.0144 | 0.5 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.0705 | 0.0532 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0144 | 0.5 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0144 | 0.5 |
Echinococcus granulosus | cpg binding protein | 0.0031 | 0.1587 | 0.1431 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.