Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | cpg binding protein | 0.003 | 0.1587 | 0.1587 |
Echinococcus granulosus | lamin dm0 | 0.0053 | 0.3054 | 0.2925 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0144 | 0.5 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0028 | 0.1488 | 0.4337 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0705 | 0.0705 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0006 | 0.0144 | 0.5 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0015 | 0.0705 | 0.0532 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0144 | 0.5 |
Echinococcus granulosus | intermediate filament protein | 0.0053 | 0.3054 | 0.2925 |
Echinococcus granulosus | GPCR family 2 | 0.0015 | 0.0705 | 0.0532 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0144 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0144 | 0.5 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0053 | 0.3054 | 1 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0015 | 0.0705 | 0.1506 |
Onchocerca volvulus | 0.0053 | 0.3054 | 1 | |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0059 | 0.3435 | 0.3435 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0288 | 0.0108 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0144 | 0.5 |
Trichomonas vaginalis | helicase, putative | 0.0006 | 0.0144 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0144 | 0.5 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0053 | 0.3054 | 1 |
Brugia malayi | CXXC zinc finger family protein | 0.0028 | 0.1488 | 0.4351 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0144 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0144 | 0.5 |
Echinococcus granulosus | cpg binding protein | 0.003 | 0.1587 | 0.1431 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0144 | 0.5 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0049 | 0.2766 | 0.8958 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0015 | 0.0705 | 0.0532 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0007 | 0.0182 | 0.0182 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0028 | 0.152 | 0.4455 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0006 | 0.0144 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.3054 | 1 |
Echinococcus multilocularis | cpg binding protein | 0.003 | 0.1587 | 0.1431 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0705 | 0.1506 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.1345 | 0.3821 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0053 | 0.3042 | 0.5 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0144 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.1812 | 0.5509 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0015 | 0.0705 | 0.0532 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0049 | 0.2766 | 0.8961 |
Loa Loa (eye worm) | intermediate filament protein | 0.0053 | 0.3054 | 1 |
Echinococcus multilocularis | GPCR, family 2 | 0.0015 | 0.0705 | 0.0532 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0705 | 0.0705 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0144 | 0.5 |
Schistosoma mansoni | intermediate filament proteins | 0.0053 | 0.3054 | 0.3054 |
Schistosoma mansoni | lamin | 0.0053 | 0.3054 | 0.3054 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.1285 | 0.3602 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0028 | 0.152 | 0.4469 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0144 | 0.5 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0288 | 0.0108 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0705 | 0.0705 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0026 | 0.1345 | 0.1184 |
Brugia malayi | intermediate filament protein | 0.0053 | 0.3054 | 1 |
Echinococcus granulosus | lamin | 0.0053 | 0.3054 | 0.2925 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 1 | 1 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0015 | 0.0705 | 0.1527 |
Echinococcus multilocularis | geminin | 0.0165 | 1 | 1 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.1587 | 0.1587 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0033 | 0.1812 | 0.552 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0144 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0144 | 0.5 |
Onchocerca volvulus | 0.0053 | 0.3054 | 1 | |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0026 | 0.1345 | 0.1184 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.2994 | 0.9781 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0705 | 0.0705 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0049 | 0.2766 | 0.8961 |
Echinococcus multilocularis | lamin | 0.0053 | 0.3054 | 0.2925 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0144 | 0.5 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0015 | 0.0705 | 0.0532 |
Echinococcus multilocularis | musashi | 0.0053 | 0.3054 | 0.2925 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0015 | 0.0705 | 0.1527 |
Schistosoma mansoni | lamin | 0.0053 | 0.3054 | 0.3054 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.1285 | 0.3602 |
Echinococcus multilocularis | lamin dm0 | 0.0053 | 0.3054 | 0.2925 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.2766 | 0.8958 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.1812 | 0.1812 |
Schistosoma mansoni | cpg binding protein | 0.0028 | 0.1488 | 0.1488 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.