Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.3082 | 0.3082 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0046 | 0.3082 | 0.5 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0074 | 1 | 1 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0046 | 0.3082 | 0.5 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0074 | 1 | 1 |
Brugia malayi | histone deacetylase 1 (HD1) | 0.0074 | 1 | 1 |
Plasmodium falciparum | histone deacetylase 2 | 0.0057 | 0.5816 | 0.3952 |
Trypanosoma brucei | histone deacetylase 4 | 0.0057 | 0.5816 | 0.3952 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0046 | 0.3082 | 0.5 |
Onchocerca volvulus | 0.0046 | 0.3082 | 0.5 | |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0046 | 0.3082 | 0.5 |
Onchocerca volvulus | 0.0046 | 0.3082 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.3082 | 0.3082 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0046 | 0.3082 | 0.5 |
Echinococcus granulosus | histone deacetylase | 0.0057 | 0.5816 | 0.3952 |
Echinococcus multilocularis | histone deacetylase 7 | 0.0057 | 0.5816 | 0.3952 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0046 | 0.3082 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0046 | 0.3082 | 0.3082 |
Schistosoma mansoni | histone deacetylase hda2 | 0.0063 | 0.7306 | 0.6105 |
Echinococcus granulosus | histone deacetylase 6 | 0.0057 | 0.5816 | 0.3952 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0046 | 0.3082 | 0.5 |
Plasmodium falciparum | histone deacetylase, putative | 0.0057 | 0.5816 | 0.3952 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.3082 | 0.3082 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0046 | 0.3082 | 0.5 |
Schistosoma mansoni | histone deacetylase | 0.0074 | 1 | 1 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0046 | 0.3082 | 0.5 |
Schistosoma mansoni | histone deacetylase | 0.0074 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 1 | 1 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0046 | 0.3082 | 0.5 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0046 | 0.3082 | 0.5 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0046 | 0.3082 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.3082 | 0.3082 |
Mycobacterium tuberculosis | Probable short-chain type oxidoreductase | 0.0046 | 0.3082 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0046 | 0.3082 | 0.5 |
Mycobacterium tuberculosis | Probable dehydrogenase/reductase | 0.0046 | 0.3082 | 0.5 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0046 | 0.3082 | 0.5 |
Loa Loa (eye worm) | histone deacetylase 1 | 0.0074 | 1 | 1 |
Mycobacterium ulcerans | short-chain dehydrogenase | 0.0046 | 0.3082 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0046 | 0.3082 | 0.5 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0074 | 1 | 1 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0046 | 0.3082 | 0.5 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0046 | 0.3082 | 0.5 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0046 | 0.3082 | 0.5 |
Mycobacterium ulcerans | short-chain membrane-associated dehydrogenase | 0.0046 | 0.3082 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0046 | 0.3082 | 0.3082 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0046 | 0.3082 | 0.5 |
Loa Loa (eye worm) | dehydrogenase | 0.0046 | 0.3082 | 0.3082 |
Mycobacterium ulcerans | 3-ketoacyl-ACP reductase | 0.0046 | 0.3082 | 0.5 |
Onchocerca volvulus | Dehydrogenase\/reductase SDR family member 1 homolog | 0.0046 | 0.3082 | 0.5 |
Schistosoma mansoni | histone deacetylase 4 5 | 0.0057 | 0.5816 | 0.3952 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0057 | 0.5816 | 0.3952 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0074 | 1 | 1 |
Echinococcus granulosus | histone deacetylase 1 | 0.0074 | 1 | 1 |
Toxoplasma gondii | histone deacetylase HDAC1 | 0.0057 | 0.5816 | 0.3952 |
Leishmania major | histone deacetylase, putative | 0.0074 | 1 | 1 |
Mycobacterium tuberculosis | Possible multi-functional enzyme with acyl-CoA-reductase activity AcrA1 | 0.0046 | 0.3082 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0046 | 0.3082 | 0.5 |
Onchocerca volvulus | 0.0046 | 0.3082 | 0.5 | |
Echinococcus multilocularis | histone deacetylase 6 | 0.0063 | 0.7306 | 0.6105 |
Onchocerca volvulus | 0.0046 | 0.3082 | 0.5 | |
Giardia lamblia | Histone deacetylase | 0.0074 | 1 | 1 |
Onchocerca volvulus | 0.0046 | 0.3082 | 0.5 | |
Echinococcus multilocularis | histone deacetylase 6 | 0.0057 | 0.5816 | 0.3952 |
Mycobacterium tuberculosis | Probable dehydrogenase/reductase | 0.0046 | 0.3082 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0046 | 0.3082 | 0.5 |
Mycobacterium ulcerans | short-chain type oxidoreductase | 0.0046 | 0.3082 | 0.5 |
Onchocerca volvulus | 0.0046 | 0.3082 | 0.5 | |
Mycobacterium tuberculosis | Possible iron-regulated short-chain dehydrogenase/reductase | 0.0046 | 0.3082 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0046 | 0.3082 | 0.3082 |
Plasmodium vivax | histone deacetylase, putative | 0.0057 | 0.5816 | 0.3952 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0046 | 0.3082 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.3082 | 0.3082 |
Trypanosoma brucei | histone deacetylase 1 | 0.0074 | 1 | 1 |
Onchocerca volvulus | 0.0046 | 0.3082 | 0.5 | |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0046 | 0.3082 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0046 | 0.3082 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.3082 | 0.3082 |
Onchocerca volvulus | 0.0046 | 0.3082 | 0.5 | |
Plasmodium vivax | histone deacetylase 2, putative | 0.0057 | 0.5816 | 0.3952 |
Mycobacterium tuberculosis | Probable shortchain dehydrogenase | 0.0046 | 0.3082 | 0.5 |
Loa Loa (eye worm) | short chain dehydrogenase/reductase family oxidoreductase | 0.0046 | 0.3082 | 0.3082 |
Onchocerca volvulus | 0.0046 | 0.3082 | 0.5 | |
Trypanosoma brucei | histone deacetylase 3 | 0.0057 | 0.5816 | 0.3952 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0046 | 0.3082 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0046 | 0.3082 | 0.3082 |
Mycobacterium tuberculosis | Possible short-chain dehydrogenase EphD | 0.0046 | 0.3082 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0046 | 0.3082 | 0.3082 |
Onchocerca volvulus | 0.0046 | 0.3082 | 0.5 | |
Plasmodium falciparum | histone deacetylase 1 | 0.0074 | 1 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0046 | 0.3082 | 0.3082 |
Toxoplasma gondii | histone deacetylase HDAC2 | 0.0074 | 1 | 1 |
Mycobacterium tuberculosis | Possible oxidoreductase | 0.0046 | 0.3082 | 0.5 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0057 | 0.5816 | 0.3952 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.3082 | 0.3082 |
Mycobacterium tuberculosis | Possible ketoacyl reductase | 0.0046 | 0.3082 | 0.5 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0046 | 0.3082 | 0.5 |
Onchocerca volvulus | 0.0046 | 0.3082 | 0.5 | |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0046 | 0.3082 | 0.5 |
Trypanosoma brucei | histone deacetylase, putative | 0.0057 | 0.5816 | 0.3952 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0046 | 0.3082 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0046 | 0.3082 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.3082 | 0.3082 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0046 | 0.3082 | 0.5 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0046 | 0.3082 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0046 | 0.3082 | 0.3082 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0046 | 0.3082 | 0.5 |
Onchocerca volvulus | Sepiapterin reductase homolog | 0.0046 | 0.3082 | 0.5 |
Mycobacterium tuberculosis | Possible oxidoreductase | 0.0046 | 0.3082 | 0.5 |
Mycobacterium leprae | Probable oxidoreductase | 0.0046 | 0.3082 | 0.5 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0046 | 0.3082 | 0.5 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.0074 | 1 | 1 |
Onchocerca volvulus | Dehydrogenase\/reductase SDR family member 13 homolog | 0.0046 | 0.3082 | 0.5 |
Echinococcus multilocularis | histone deacetylase | 0.0057 | 0.5816 | 0.3952 |
Entamoeba histolytica | histone deacetylase, putative | 0.0074 | 1 | 1 |
Brugia malayi | Histone deacetylase family protein | 0.0057 | 0.5816 | 0.3952 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0046 | 0.3082 | 0.5 |
Toxoplasma gondii | histone deacetylase HDAC3 | 0.0074 | 1 | 1 |
Brugia malayi | Histone deacetylase family protein | 0.0057 | 0.5816 | 0.3952 |
Plasmodium vivax | histone deacetylase 1, putative | 0.0074 | 1 | 1 |
Mycobacterium ulcerans | dehydrogenase/reductase | 0.0046 | 0.3082 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0046 | 0.3082 | 0.5 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.0074 | 1 | 1 |
Mycobacterium ulcerans | carveol-like dehydrogenase | 0.0046 | 0.3082 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0046 | 0.3082 | 0.5 |
Echinococcus granulosus | histone deacetylase 3 | 0.0074 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.3082 | 0.3082 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0046 | 0.3082 | 0.5 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0057 | 0.5816 | 0.3952 |
Loa Loa (eye worm) | histone deacetylase 7A | 0.0057 | 0.5816 | 0.5816 |
Echinococcus multilocularis | histone deacetylase 3 | 0.0074 | 1 | 1 |
Mycobacterium leprae | Possible short-chain dehydrogenase EphD | 0.0046 | 0.3082 | 0.5 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0046 | 0.3082 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.3082 | 0.3082 |
Mycobacterium leprae | ROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE | 0.0046 | 0.3082 | 0.5 |
Loa Loa (eye worm) | dehydrogenase | 0.0046 | 0.3082 | 0.3082 |
Trypanosoma cruzi | histone deacetylase 1, putative | 0.0074 | 1 | 1 |
Mycobacterium ulcerans | 3-alpha-hydroxysteroid dehydrogenase | 0.0046 | 0.3082 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.3082 | 0.3082 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0046 | 0.3082 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0046 | 0.3082 | 0.5 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.0074 | 1 | 1 |
Leishmania major | histone deacetylase, putative | 0.0074 | 1 | 1 |
Mycobacterium ulcerans | ketoacyl reductase | 0.0046 | 0.3082 | 0.5 |
Mycobacterium leprae | Probable short-chain type dehydrogenase/reductase | 0.0046 | 0.3082 | 0.5 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0074 | 1 | 1 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0046 | 0.3082 | 0.5 |
Mycobacterium tuberculosis | Probable short chain alcohol dehydrogenase/reductase | 0.0046 | 0.3082 | 0.5 |
Mycobacterium ulcerans | dehydrogenase | 0.0046 | 0.3082 | 0.5 |
Mycobacterium ulcerans | dehydrogenase/decarboxylase protein | 0.0046 | 0.3082 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0046 | 0.3082 | 0.5 |
Mycobacterium ulcerans | short-chain dehydrogenase | 0.0046 | 0.3082 | 0.5 |
Mycobacterium tuberculosis | Possible fatty acyl-CoA reductase | 0.0046 | 0.3082 | 0.5 |
Loa Loa (eye worm) | histone deacetylase | 0.0057 | 0.5816 | 0.5816 |
Mycobacterium tuberculosis | Probable short-chain dehydrogenase/reductase | 0.0046 | 0.3082 | 0.5 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0057 | 0.5816 | 0.3952 |
Mycobacterium ulcerans | ketoacyl reductase | 0.0046 | 0.3082 | 0.5 |
Brugia malayi | Histone deacetylase 1 | 0.0074 | 1 | 1 |
Mycobacterium leprae | PROBABLE SHORT CHAIN ALCOHOL DEHYDROGENASE/REDUCTASE | 0.0046 | 0.3082 | 0.5 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0074 | 1 | 1 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0046 | 0.3082 | 0.5 |
Onchocerca volvulus | Dehydrogenase\/reductase SDR family member 13 homolog | 0.0046 | 0.3082 | 0.5 |
Onchocerca volvulus | 0.0046 | 0.3082 | 0.5 | |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0046 | 0.3082 | 0.5 |
Echinococcus granulosus | histone deacetylase 6 | 0.0063 | 0.7306 | 0.6105 |
Echinococcus granulosus | histone deacetylase 7 | 0.0057 | 0.5816 | 0.3952 |
Mycobacterium tuberculosis | Decaprenylphosphoryl-D-2-keto erythro pentose reductase | 0.0046 | 0.3082 | 0.5 |
Mycobacterium ulcerans | ketoacyl reductase | 0.0046 | 0.3082 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0046 | 0.3082 | 0.3082 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0046 | 0.3082 | 0.5 |
Trypanosoma cruzi | histone deacetylase 1, putative | 0.0074 | 1 | 1 |
Schistosoma mansoni | histone deacetylase 4 5 | 0.0057 | 0.5816 | 0.3952 |
Echinococcus multilocularis | histone deacetylase 1 | 0.0074 | 1 | 1 |
Mycobacterium ulcerans | oxidoreductase | 0.0046 | 0.3082 | 0.5 |
Mycobacterium leprae | Probable short-chain type dehydrogenase/reductase | 0.0046 | 0.3082 | 0.5 |
Leishmania major | histone deacetylase, putative | 0.0057 | 0.5816 | 0.3952 |
Mycobacterium ulcerans | short-chain dehydrogenase | 0.0046 | 0.3082 | 0.5 |
Loa Loa (eye worm) | histone deacetylase 3 | 0.0074 | 1 | 1 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0046 | 0.3082 | 0.5 |
Mycobacterium ulcerans | oxidoreductase | 0.0046 | 0.3082 | 0.5 |
Leishmania major | histone deacetylase, putative | 0.0057 | 0.5816 | 0.3952 |
Mycobacterium ulcerans | short-chain dehydrogenase | 0.0046 | 0.3082 | 0.5 |
Echinococcus granulosus | histone deacetylase 6 | 0.0057 | 0.5816 | 0.3952 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0046 | 0.3082 | 0.5 |
Onchocerca volvulus | 0.0046 | 0.3082 | 0.5 | |
Wolbachia endosymbiont of Brugia malayi | Short-chain alcohol dehydrogenase family enzyme | 0.0046 | 0.3082 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0046 | 0.3082 | 0.3082 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.