Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0011 | 0.0011 |
Leishmania major | DNA polymerase kappa, putative | 0.0019 | 0.0015 | 0.004 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0016 | 0.0008 | 0.0008 |
Brugia malayi | Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 | 0.0033 | 0.0042 | 0.0042 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0031 | 0.0039 | 0.0039 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C54, putative | 0.0022 | 0.0022 | 0.0057 |
Onchocerca volvulus | Alhambra homolog | 0.0029 | 0.0035 | 0.0046 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0035 | 0.0047 | 0.5131 |
Echinococcus granulosus | cysteine protease atg4b | 0.0058 | 0.0092 | 0.0092 |
Brugia malayi | Phospholipase A2 family protein | 0.009 | 0.0156 | 0.0156 |
Echinococcus granulosus | insulin growth factor 1 receptor beta | 0.0057 | 0.009 | 0.009 |
Leishmania major | DNA polymerase eta, putative | 0.0031 | 0.0039 | 0.0103 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0016 | 0.0008 | 0.0022 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0026 | 0.0026 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0015 | 0.004 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0225 | 0.0423 | 0.0415 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0053 | 0.0053 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0012 | 0.0012 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0019 | 0.0015 | 0.0007 |
Schistosoma mansoni | tyrosine kinase | 0.0057 | 0.009 | 0.009 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.012 | 0.0215 | 0.0215 |
Schistosoma mansoni | tyrosine kinase | 0.0093 | 0.0161 | 0.0161 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0013 | 0.0003 | 0.0003 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0096 | 0.0167 | 0.0167 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0016 | 0.0008 | 0.0008 |
Plasmodium falciparum | phd finger protein, putative | 0.0029 | 0.0035 | 0.0092 |
Echinococcus granulosus | tumor protein p63 | 0.0339 | 0.0651 | 0.0651 |
Trypanosoma cruzi | AUT2/APG4/ATG4 cysteine peptidase, putative | 0.0058 | 0.0092 | 0.024 |
Schistosoma mansoni | cpg binding protein | 0.0032 | 0.0041 | 0.0041 |
Echinococcus granulosus | cpg binding protein | 0.0032 | 0.0041 | 0.0041 |
Plasmodium falciparum | bifunctional dihydrofolate reductase-thymidylate synthase | 0.193 | 0.3809 | 1 |
Echinococcus granulosus | lamin dm0 | 0.0027 | 0.0032 | 0.0032 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0039 | 0.0039 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0015 | 0.004 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0007 | 0.0007 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0036 | 0.0048 | 0.0048 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0045 | 0.0066 | 0.0172 |
Trichomonas vaginalis | Clan CA, family C54, ATG4-like cysteine peptidase | 0.0058 | 0.0092 | 1 |
Entamoeba histolytica | peptidyl-prolyl cis-trans isomerase, putative | 0.0032 | 0.004 | 0.2456 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0039 | 0.0054 | 0.0054 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0013 | 0.0003 | 0.0009 |
Schistosoma mansoni | tyrosine kinase | 0.0093 | 0.0161 | 0.0161 |
Mycobacterium ulcerans | lipase LipD | 0.0035 | 0.0047 | 0.0032 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0096 | 0.0167 | 0.0167 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0025 | 0.0026 | 0.0068 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0003 | 0.0003 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0029 | 0.0035 | 0.0092 |
Onchocerca volvulus | Tyrosine kinase homolog | 0.0166 | 0.0307 | 0.3471 |
Brugia malayi | PHD-finger family protein | 0.0029 | 0.0035 | 0.0035 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0035 | 0.0047 | 0.0032 |
Schistosoma mansoni | nephrin | 0.0014 | 0.0004 | 0.0004 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0031 | 0.0039 | 0.0103 |
Brugia malayi | Isocitrate dehydrogenase | 0.0016 | 0.0008 | 0.0008 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0035 | 0.0047 | 0.0123 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0002 | 0.0002 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.0015 | 0.004 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0019 | 0.0015 | 0.1663 |
Echinococcus granulosus | high affinity cAMP specific 3'5' cyclic | 0.0397 | 0.0766 | 0.0766 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0015 | 0.004 |
Schistosoma mansoni | rotamase | 0.0033 | 0.0042 | 0.0042 |
Echinococcus granulosus | GPCR family 2 | 0.0031 | 0.0039 | 0.0039 |
Toxoplasma gondii | ABC1 family protein | 0.0035 | 0.0047 | 0.0123 |
Loa Loa (eye worm) | Pin1-type peptidyl-prolyl cis-trans isomerase | 0.0033 | 0.0042 | 0.0042 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0031 | 0.0039 | 0.0039 |
Schistosoma mansoni | DNA polymerase eta | 0.0045 | 0.0066 | 0.0066 |
Mycobacterium ulcerans | beta-lactamase | 0.0035 | 0.0047 | 0.0032 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0008 | 0.0008 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.0015 | 0.004 |
Schistosoma mansoni | tyrosine kinase | 0.0175 | 0.0325 | 0.0325 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.005 | 0.0076 | 0.0076 |
Echinococcus multilocularis | cysteine protease atg4b | 0.0058 | 0.0092 | 0.0092 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0018 | 0.0012 | 0.0012 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.0015 | 0.004 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0031 | 0.0039 | 0.0039 |
Echinococcus multilocularis | musashi | 0.0027 | 0.0032 | 0.0032 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase | 0.0032 | 0.004 | 0.0106 |
Entamoeba histolytica | peptidase, C54 family | 0.0058 | 0.0092 | 0.7448 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0019 | 0.0015 | 0.0015 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0015 | 0.004 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.0095 | 0.0165 | 0.0165 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0003 | 0.0003 |
Schistosoma mansoni | jumonji domain containing protein | 0.0076 | 0.0128 | 0.0128 |
Entamoeba histolytica | hypothetical protein | 0.0071 | 0.0118 | 1 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0035 | 0.0047 | 0.5131 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0039 | 0.0054 | 0.0054 |
Echinococcus granulosus | expressed protein | 0.0033 | 0.0042 | 0.0042 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0071 | 0.0118 | 0.0118 |
Echinococcus granulosus | dihydrofolate reductase | 0.5047 | 1 | 1 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0039 | 0.0054 | 0.0054 |
Brugia malayi | intermediate filament protein | 0.0027 | 0.0032 | 0.0032 |
Loa Loa (eye worm) | hypothetical protein | 0.0098 | 0.0172 | 0.0172 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.012 | 0.0215 | 0.02 |
Mycobacterium tuberculosis | Conserved protein | 0.0035 | 0.0047 | 0.0039 |
Echinococcus multilocularis | insulin receptor | 0.0057 | 0.009 | 0.009 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0031 | 0.0039 | 0.0039 |
Onchocerca volvulus | 0.0035 | 0.0047 | 0.0194 | |
Leishmania major | hypothetical protein, conserved | 0.0035 | 0.0047 | 0.0123 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0018 | 0.0012 | 0.0012 |
Onchocerca volvulus | 0.005 | 0.0076 | 0.0556 | |
Loa Loa (eye worm) | intermediate filament protein | 0.0027 | 0.0032 | 0.0032 |
Trichomonas vaginalis | Clan CA, family C54, ATG4-like cysteine peptidase | 0.0058 | 0.0092 | 1 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0031 | 0.0039 | 0.0039 |
Entamoeba histolytica | peptidase, C54 family | 0.0022 | 0.0022 | 0.0635 |
Leishmania major | AUT2/APG4/ATG4 cysteine peptidase, putative | 0.0022 | 0.0022 | 0.0057 |
Schistosoma mansoni | hypothetical protein | 0.0021 | 0.0018 | 0.0018 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.012 | 0.0215 | 0.0215 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0013 | 0.0003 | 0.0003 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0026 | 0.0068 |
Schistosoma mansoni | tyrosine kinase | 0.0095 | 0.0165 | 0.0165 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0015 | 0.004 |
Echinococcus granulosus | melanoma receptor tyrosine protein kinase | 0.0095 | 0.0165 | 0.0165 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0047 | 0.0047 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0029 | 0.0035 | 0.0035 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0035 | 0.0047 | 0.0039 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0031 | 0.0031 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0066 | 0.0066 |
Leishmania major | DNA polymerase eta, putative | 0.0045 | 0.0066 | 0.0172 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0035 | 0.0047 | 0.0039 |
Echinococcus granulosus | epidermal growth factor receptor | 0.0175 | 0.0325 | 0.0325 |
Schistosoma mansoni | tyrosine kinase | 0.0093 | 0.0161 | 0.0161 |
Echinococcus granulosus | epidermal growth factor receptor | 0.0095 | 0.0165 | 0.0165 |
Schistosoma mansoni | hypothetical protein | 0.0067 | 0.011 | 0.011 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0035 | 0.0047 | 0.0047 |
Schistosoma mansoni | hypothetical protein | 0.0405 | 0.0782 | 0.0782 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0071 | 0.0118 | 0.0118 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0035 | 0.0047 | 0.5131 |
Schistosoma mansoni | hypothetical protein | 0.0029 | 0.0035 | 0.0035 |
Brugia malayi | beta-lactamase family protein | 0.0035 | 0.0047 | 0.0047 |
Loa Loa (eye worm) | beta-lactamase | 0.0035 | 0.0047 | 0.0047 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0016 | 0.0008 | 0.0022 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0178 | 0.033 | 0.033 |
Brugia malayi | jmjC domain containing protein | 0.0039 | 0.0054 | 0.0054 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0035 | 0.0047 | 0.0047 |
Leishmania major | AUT2/APG4/ATG4 cysteine peptidase, putative | 0.0058 | 0.0092 | 0.024 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0047 | 0.0047 |
Plasmodium vivax | hypothetical protein, conserved | 0.0029 | 0.0035 | 0.0092 |
Leishmania major | hypothetical protein, conserved | 0.0025 | 0.0026 | 0.0068 |
Giardia lamblia | PHD finger protein 15 | 0.0029 | 0.0035 | 1 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0035 | 0.0047 | 0.0032 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0033 | 0.0042 | 0.4579 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0098 | 0.0172 | 0.0172 |
Echinococcus granulosus | Jumonji AT rich interactive domain 1B | 0.0013 | 0.0003 | 0.0003 |
Echinococcus multilocularis | Peptidase C54 | 0.0058 | 0.0092 | 0.0092 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.0026 | 0.0068 |
Brugia malayi | hypothetical protein | 0.0016 | 0.0009 | 0.0009 |
Trypanosoma cruzi | AUT2/APG4/ATG4 cysteine peptidase, putative | 0.0022 | 0.0022 | 0.0057 |
Echinococcus granulosus | jumonji domain containing protein | 0.0041 | 0.0058 | 0.0058 |
Schistosoma mansoni | tyrosine kinase | 0.0057 | 0.009 | 0.009 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0002 | 0.0002 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase | 0.0032 | 0.004 | 0.0106 |
Brugia malayi | Dihydrofolate reductase | 0.5047 | 1 | 1 |
Mycobacterium tuberculosis | Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) | 0.5047 | 1 | 1 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0029 | 0.0035 | 0.0035 |
Echinococcus granulosus | twitchin | 0.0015 | 0.0007 | 0.0007 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0016 | 0.0008 | 0.0022 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0016 | 0.0008 | 0.0008 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0035 | 0.0047 | 0.0123 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0035 | 0.0047 | 0.5131 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0024 | 0.0025 | 0.0025 |
Schistosoma mansoni | cell adhesion molecule | 0.0014 | 0.0006 | 0.0006 |
Entamoeba histolytica | hypothetical protein | 0.0071 | 0.0118 | 1 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0028 | 0.0034 | 0.0034 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0019 | 0.0015 | 0.004 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0039 | 0.0039 |
Schistosoma mansoni | lamin | 0.0027 | 0.0032 | 0.0032 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.0156 | 0.0156 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0015 | 0.004 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0008 | 0.0008 |
Echinococcus multilocularis | high affinity cAMP specific 3',5' cyclic | 0.0397 | 0.0766 | 0.0766 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0024 | 0.0025 | 0.0025 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0047 | 0.0047 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0026 | 0.0068 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0035 | 0.0047 | 0.0039 |
Onchocerca volvulus | Phospholipase A2 homolog | 0.009 | 0.0156 | 0.1563 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0077 | 0.0077 |
Echinococcus granulosus | lamin | 0.0027 | 0.0032 | 0.0032 |
Echinococcus granulosus | dna polymerase eta | 0.0045 | 0.0066 | 0.0066 |
Echinococcus multilocularis | dna polymerase eta | 0.0045 | 0.0066 | 0.0066 |
Entamoeba histolytica | peptidase, C54 family | 0.0022 | 0.0022 | 0.0635 |
Leishmania major | peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative | 0.0032 | 0.004 | 0.0106 |
Trypanosoma cruzi | ISWI complex protein | 0.0015 | 0.0007 | 0.0019 |
Echinococcus multilocularis | methyl CpG binding domain protein 2 | 0.0017 | 0.0011 | 0.0011 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0017 | 0.001 | 0.001 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0047 | 0.0047 |
Schistosoma mansoni | cpg binding protein | 0.0032 | 0.0041 | 0.0041 |
Echinococcus multilocularis | GPCR, family 2 | 0.0031 | 0.0039 | 0.0039 |
Echinococcus granulosus | dna polymerase kappa | 0.0019 | 0.0015 | 0.0015 |
Echinococcus granulosus | peregrin | 0.0032 | 0.004 | 0.004 |
Echinococcus multilocularis | expressed protein | 0.0033 | 0.0042 | 0.0042 |
Leishmania major | hypothetical protein, conserved | 0.0015 | 0.0007 | 0.0019 |
Echinococcus multilocularis | neuroglian | 0.0014 | 0.0004 | 0.0004 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0039 | 0.0039 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.006 | 0.0097 | 0.0097 |
Entamoeba histolytica | hypothetical protein | 0.0071 | 0.0118 | 1 |
Schistosoma mansoni | zinc finger protein | 0.0015 | 0.0007 | 0.0007 |
Echinococcus granulosus | zinc finger protein | 0.0021 | 0.0019 | 0.0019 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0013 | 0.0003 | 0.0009 |
Brugia malayi | Protein kinase domain containing protein | 0.0057 | 0.009 | 0.009 |
Echinococcus multilocularis | Jumonji, AT rich interactive domain 1B | 0.0013 | 0.0003 | 0.0003 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0035 | 0.0047 | 0.0047 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0018 | 0.0012 | 0.0012 |
Trichomonas vaginalis | esterase, putative | 0.0035 | 0.0047 | 0.5131 |
Mycobacterium leprae | DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) | 0.5047 | 1 | 1 |
Trichomonas vaginalis | rotamase, putative | 0.0033 | 0.0042 | 0.4579 |
Toxoplasma gondii | ImpB/MucB/SamB family protein | 0.0031 | 0.0039 | 0.0103 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.012 | 0.0215 | 0.0215 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0041 | 0.0058 | 0.0058 |
Giardia lamblia | DINP protein human, muc B family | 0.0019 | 0.0015 | 0.4322 |
Schistosoma mansoni | bromodomain containing protein | 0.0065 | 0.0105 | 0.0105 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0035 | 0.0047 | 0.0047 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0015 | 0.0006 | 0.0006 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0019 | 0.0015 | 0.1663 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0067 | 0.011 | 0.011 |
Trichomonas vaginalis | Clan CA, family C54, ATG4-like cysteine peptidase | 0.0058 | 0.0092 | 1 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.012 | 0.0215 | 0.0564 |
Toxoplasma gondii | autophagy-related cysteine peptidase atg4, putative | 0.0022 | 0.0022 | 0.0057 |
Trypanosoma brucei | ISWI complex protein | 0.0015 | 0.0007 | 0.0019 |
Onchocerca volvulus | 0.0161 | 0.0298 | 0.3352 | |
Echinococcus granulosus | roundabout 2 | 0.0017 | 0.0011 | 0.0011 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0016 | 0.0008 | 0.0008 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0015 | 0.0006 | 0.0006 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0045 | 0.0066 | 0.0066 |
Schistosoma mansoni | lamin | 0.0027 | 0.0032 | 0.0032 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0047 | 0.0047 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0035 | 0.0047 | 0.0039 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.0015 | 0.004 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0019 | 0.0015 | 0.0015 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0015 | 0.004 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0018 | 0.0012 | 0.0012 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.0175 | 0.0325 | 0.0325 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0035 | 0.0047 | 0.0039 |
Echinococcus multilocularis | peregrin | 0.0032 | 0.004 | 0.004 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.0015 | 0.004 |
Brugia malayi | beta-lactamase family protein | 0.0035 | 0.0047 | 0.0047 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0058 | 0.0058 |
Echinococcus multilocularis | roundabout 2 | 0.0017 | 0.0011 | 0.0011 |
Echinococcus multilocularis | dna polymerase kappa | 0.0019 | 0.0015 | 0.0015 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0031 | 0.0039 | 0.0039 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0021 | 0.0018 | 0.0018 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.012 | 0.0215 | 0.0215 |
Trichomonas vaginalis | rotamase, putative | 0.0032 | 0.004 | 0.4412 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0015 | 0.004 |
Mycobacterium tuberculosis | Conserved protein | 0.0035 | 0.0047 | 0.0039 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0039 | 0.0054 | 0.0054 |
Mycobacterium ulcerans | dihydrofolate reductase DfrA | 0.5047 | 1 | 1 |
Brugia malayi | beta-lactamase | 0.0035 | 0.0047 | 0.0047 |
Plasmodium falciparum | cysteine protease ATG4, putative | 0.0022 | 0.0022 | 0.0057 |
Schistosoma mansoni | tyrosine kinase | 0.0095 | 0.0165 | 0.0165 |
Onchocerca volvulus | 0.0035 | 0.0047 | 0.0194 | |
Schistosoma mansoni | zinc finger protein | 0.0021 | 0.0019 | 0.0019 |
Echinococcus granulosus | insulin receptor | 0.0057 | 0.009 | 0.009 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0035 | 0.0047 | 0.0047 |
Plasmodium vivax | isocitrate dehydrogenase [NADP], mitochondrial, putative | 0.0016 | 0.0008 | 0.0022 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0035 | 0.0047 | 0.0047 |
Echinococcus multilocularis | lamin | 0.0027 | 0.0032 | 0.0032 |
Echinococcus granulosus | methyl CpG binding domain protein 2 | 0.0017 | 0.0011 | 0.0011 |
Trichomonas vaginalis | Clan CA, family C54, ATG4-like cysteine peptidase | 0.0058 | 0.0092 | 1 |
Echinococcus multilocularis | zinc finger protein | 0.0021 | 0.0019 | 0.0019 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0098 | 0.0172 | 0.0172 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0029 | 0.0035 | 0.0092 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0027 | 0.0032 | 0.0032 |
Onchocerca volvulus | 0.0035 | 0.0047 | 0.0194 | |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0032 | 0.0032 |
Loa Loa (eye worm) | hypothetical protein | 0.0427 | 0.0825 | 0.0825 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0016 | 0.0008 | 0.0022 |
Entamoeba histolytica | peptidase, C54 family | 0.0022 | 0.0022 | 0.0635 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0035 | 0.0047 | 0.0123 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0024 | 0.0025 | 0.0025 |
Onchocerca volvulus | Phospholipase A2 homolog | 0.0427 | 0.0825 | 1 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.006 | 0.0097 | 0.0097 |
Trypanosoma cruzi | ISWI complex protein | 0.0015 | 0.0007 | 0.0019 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0025 | 0.0026 | 0.0068 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0035 | 0.0047 | 0.0039 |
Echinococcus granulosus | neurotracting:lsamp:neurotrimin:obcam | 0.0014 | 0.0006 | 0.0006 |
Trypanosoma brucei | AUT2/APG4/ATG4 cysteine peptidase, putative | 0.0058 | 0.0092 | 0.024 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0019 | 0.0015 | 0.0015 |
Echinococcus multilocularis | insulin growth factor 1 receptor beta | 0.0057 | 0.009 | 0.009 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0015 | 0.004 |
Entamoeba histolytica | peptidase, C54 family | 0.0022 | 0.0022 | 0.0635 |
Brugia malayi | Peptidase family C54 containing protein | 0.0058 | 0.0092 | 0.0092 |
Echinococcus granulosus | Peptidase C54 | 0.0058 | 0.0092 | 0.0092 |
Echinococcus multilocularis | 0.0054 | 0.0084 | 0.0084 | |
Loa Loa (eye worm) | dihydrofolate reductase | 0.5047 | 1 | 1 |
Trypanosoma brucei | unspecified product | 0.0013 | 0.0003 | 0.0009 |
Plasmodium falciparum | isocitrate dehydrogenase [NADP], mitochondrial | 0.0016 | 0.0008 | 0.0022 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0045 | 0.0066 | 0.0172 |
Brugia malayi | jmjC domain containing protein | 0.0096 | 0.0167 | 0.0167 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0016 | 0.0008 | 0.0022 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.012 | 0.0215 | 0.02 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0017 | 0.0011 | 0.0011 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.0029 | 0.0035 | 0.0035 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0065 | 0.0065 |
Brugia malayi | hypothetical protein | 0.0071 | 0.0118 | 0.0118 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0806 | 0.1579 | 0.1579 |
Toxoplasma gondii | bifunctional dihydrofolate reductase-thymidylate synthase | 0.193 | 0.3809 | 1 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0019 | 0.0015 | 0.0015 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.002 | 0.0017 | 0.0017 |
Trypanosoma brucei | dihydrofolate reductase-thymidylate synthase | 0.193 | 0.3809 | 1 |
Plasmodium vivax | bifunctional dihydrofolate reductase-thymidylate synthase, putative | 0.193 | 0.3809 | 1 |
Schistosoma mansoni | dihydrofolate reductase | 0.5047 | 1 | 1 |
Loa Loa (eye worm) | TK/KIN16 protein kinase | 0.0178 | 0.033 | 0.033 |
Schistosoma mansoni | autophagin-1 (C54 family) | 0.0058 | 0.0092 | 0.0092 |
Trichomonas vaginalis | Clan CA, family C54, ATG4-like cysteine peptidase | 0.0058 | 0.0092 | 1 |
Schistosoma mansoni | intermediate filament proteins | 0.0027 | 0.0032 | 0.0032 |
Brugia malayi | Furin-like cysteine rich region family protein | 0.0175 | 0.0325 | 0.0325 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0076 | 0.0076 |
Onchocerca volvulus | 0.0028 | 0.0034 | 0.0025 | |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0098 | 0.0172 | 0.0172 |
Schistosoma mansoni | family C54 unassigned peptidase (C54 family) | 0.0058 | 0.0092 | 0.0092 |
Schistosoma mansoni | hypothetical protein | 0.0071 | 0.0118 | 0.0118 |
Trypanosoma brucei | peptidyl-prolyl cis-trans isomerase/rotamase, putative | 0.0032 | 0.004 | 0.0106 |
Brugia malayi | Bromodomain containing protein | 0.0076 | 0.0128 | 0.0128 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0019 | 0.0015 | 0.0015 |
Trypanosoma brucei | unspecified product | 0.0019 | 0.0015 | 0.004 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0019 | 0.0015 | 0.0007 |
Brugia malayi | CXXC zinc finger family protein | 0.0028 | 0.0034 | 0.0034 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.012 | 0.0215 | 0.0564 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0017 | 0.0011 | 0.0011 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.0117 | 0.0117 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.012 | 0.0215 | 0.02 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0047 | 0.0047 |
Mycobacterium ulcerans | hypothetical protein | 0.0035 | 0.0047 | 0.0032 |
Echinococcus multilocularis | lamin dm0 | 0.0027 | 0.0032 | 0.0032 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0039 | 0.0039 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0031 | 0.0039 | 0.0039 |
Leishmania major | dihydrofolate reductase-thymidylate synthase | 0.193 | 0.3809 | 1 |
Echinococcus granulosus | neuroglian | 0.0014 | 0.0004 | 0.0004 |
Brugia malayi | isocitrate dehydrogenase | 0.0016 | 0.0008 | 0.0008 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.0015 | 0.004 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0039 | 0.0039 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0015 | 0.004 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0019 | 0.0015 | 0.0015 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0056 | 0.0089 | 0.0233 |
Schistosoma mansoni | cpg binding protein | 0.0028 | 0.0034 | 0.0034 |
Entamoeba histolytica | hypothetical protein | 0.0071 | 0.0118 | 1 |
Brugia malayi | Bromodomain containing protein | 0.0038 | 0.0053 | 0.0053 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0035 | 0.0047 | 0.5131 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0011 | 0.0011 |
Echinococcus granulosus | dnaJ subfamily B | 0.0405 | 0.0782 | 0.0782 |
Echinococcus granulosus | intermediate filament protein | 0.0027 | 0.0032 | 0.0032 |
Chlamydia trachomatis | dihydrofolate reductase | 0.5047 | 1 | 0.5 |
Echinococcus multilocularis | dihydrofolate reductase | 0.5047 | 1 | 1 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0016 | 0.0008 | 0.0022 |
Echinococcus multilocularis | cpg binding protein | 0.0032 | 0.0041 | 0.0041 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0008 | 0.0008 |
Brugia malayi | Bromodomain containing protein | 0.0032 | 0.004 | 0.004 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0025 | 0.0026 | 0.0068 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.0092 | 0.0092 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0061 | 0.0098 | 0.0098 |
Schistosoma mansoni | family C54 unassigned peptidase (C54 family) | 0.0058 | 0.0092 | 0.0092 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0013 | 0.0003 | 0.0009 |
Trypanosoma brucei | unspecified product | 0.0013 | 0.0003 | 0.0009 |
Brugia malayi | PHD-finger family protein | 0.0026 | 0.003 | 0.003 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.011 | 0.011 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase | 0.193 | 0.3809 | 1 |
Plasmodium vivax | hypothetical protein, conserved | 0.0035 | 0.0047 | 0.0123 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.0026 | 0.0068 |
Mycobacterium tuberculosis | Conserved protein | 0.0035 | 0.0047 | 0.0039 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.0015 | 0.004 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0008 | 0.0008 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0006 | 0.0006 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0029 | 0.0035 | 0.0035 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0027 | 0.0032 | 0.0032 |
Trypanosoma cruzi | cysteine peptidase, Clan CA, family C54, putative | 0.0022 | 0.0022 | 0.0057 |
Brugia malayi | PHD-finger family protein | 0.0013 | 0.0003 | 0.0003 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0405 | 0.0782 | 0.0782 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.012 | 0.0215 | 0.0207 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0016 | 0.0008 | 0.0022 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0018 | 0.0012 | 0.0012 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0035 | 0.0035 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0071 | 0.0118 | 0.0118 |
Loa Loa (eye worm) | TK/EGFR protein kinase | 0.0175 | 0.0325 | 0.0325 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0036 | 0.0048 | 0.0048 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0035 | 0.0047 | 0.0047 |
Echinococcus multilocularis | tumor protein p63 | 0.0339 | 0.0651 | 0.0651 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0061 | 0.0098 | 0.0098 |
Toxoplasma gondii | peptidylprolyl isomerase | 0.0032 | 0.004 | 0.0106 |
Loa Loa (eye worm) | TK/INSR protein kinase | 0.0057 | 0.009 | 0.009 |
Brugia malayi | hypothetical protein | 0.0025 | 0.0026 | 0.0026 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0035 | 0.0047 | 0.0039 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.