Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | CMGC family protein kinase | 0.1028 | 1 | 0.5 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0069 | 0.0292 | 0.0172 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.1028 | 1 | 1 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.1028 | 1 | 1 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.1028 | 1 | 1 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.1028 | 1 | 1 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.1028 | 1 | 1 |
Giardia lamblia | Kinase, CMGC MAPK | 0.1028 | 1 | 0.5 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.1028 | 1 | 1 |
Echinococcus granulosus | mitogen activated protein kinase | 0.1028 | 1 | 1 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0717 | 0.6851 | 0.6756 |
Onchocerca volvulus | 0.0148 | 0.1092 | 0.5 | |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.0069 | 0.0292 | 0.0292 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.1028 | 1 | 1 |
Trypanosoma brucei | protein kinase, putative | 0.1028 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0148 | 0.1092 | 0.0982 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0717 | 0.6851 | 0.6851 |
Trichomonas vaginalis | CMGC family protein kinase | 0.1028 | 1 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.1028 | 1 | 0.5 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.1028 | 1 | 1 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.0069 | 0.0292 | 0.0172 |
Schistosoma mansoni | serine/threonine protein kinase | 0.1028 | 1 | 1 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.1028 | 1 | 0.5 |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.0069 | 0.0292 | 0.5 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.1028 | 1 | 1 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.1028 | 1 | 1 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.0069 | 0.0292 | 0.0292 |
Trichomonas vaginalis | CMGC family protein kinase | 0.1028 | 1 | 0.5 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.1028 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0148 | 0.1092 | 0.0982 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0717 | 0.6851 | 0.6851 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.