Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | ubiquitin-activating enzyme E1, putative | 0.1469 | 0.7158 | 1 |
Loa Loa (eye worm) | ectopic membrane ruffles in embryo protein 1 | 0.2034 | 1 | 1 |
Schistosoma mansoni | ubiquitin-activating enzyme E1C | 0.2034 | 1 | 1 |
Trypanosoma brucei | NEDD8 activating enzyme subunit, putative | 0.0635 | 0.2962 | 1 |
Echinococcus granulosus | ubiquitin modifier activating enzyme ATG7 | 0.0071 | 0.012 | 0.003 |
Brugia malayi | ThiF family protein | 0.0071 | 0.012 | 0.003 |
Loa Loa (eye worm) | glyceraldehyde 3-phosphate dehydrogenase | 0.0173 | 0.0635 | 0.0627 |
Onchocerca volvulus | Equilibrative nucleoside transporter, putative homolog | 0.0238 | 0.0962 | 1 |
Trypanosoma cruzi | adenosine kinase, putative | 0.0171 | 0.0626 | 0.1867 |
Trypanosoma cruzi | adenosine kinase, putative | 0.0171 | 0.0626 | 0.1867 |
Chlamydia trachomatis | glyceraldehyde-3-phosphate dehydrogenase | 0.0264 | 0.1093 | 0.5 |
Brugia malayi | ThiF family protein | 0.0117 | 0.0355 | 0.0267 |
Trypanosoma brucei | E1-like ubiquitin-activating enzyme, putative | 0.0071 | 0.012 | 0.0105 |
Loa Loa (eye worm) | hypothetical protein | 0.0108 | 0.0308 | 0.03 |
Entamoeba histolytica | molybdenum cofactor synthesis protein3, putative | 0.0071 | 0.012 | 0.003 |
Schistosoma mansoni | adenosine kinase | 0.0171 | 0.0626 | 0.0626 |
Echinococcus multilocularis | equilibrative nucleoside transporter 3 | 0.0238 | 0.0962 | 0.088 |
Echinococcus granulosus | ubiquitin modifier activating enzyme 1 | 0.0204 | 0.079 | 0.0707 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0048 | 0.0008 | 0.0008 |
Trichomonas vaginalis | molybdopterin biosynthesis moeb protein, putative | 0.0635 | 0.2962 | 0.4038 |
Mycobacterium tuberculosis | Probable glyceraldehyde 3-phosphate dehydrogenase Gap (GAPDH) | 0.0091 | 0.0224 | 0.043 |
Trichomonas vaginalis | equilibrative nucleoside transporter, putative | 0.0238 | 0.0962 | 0.1196 |
Leishmania major | ubiquitin-activating enzyme-like protein | 0.0071 | 0.012 | 0.0105 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0173 | 0.0635 | 0.0732 |
Trypanosoma brucei | ubiquitin activating enzyme, putative | 0.0071 | 0.012 | 0.0105 |
Echinococcus multilocularis | ubiquitin modifier activating enzyme 6 | 0.0204 | 0.079 | 0.0707 |
Toxoplasma gondii | ThiF family protein | 0.0081 | 0.0174 | 0.0055 |
Giardia lamblia | Glyceraldehyde 3-phosphate dehydrogenase | 0.0264 | 0.1093 | 1 |
Plasmodium vivax | ubiquitin activating enzyme, putative | 0.0117 | 0.0355 | 0.0827 |
Schistosoma mansoni | glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) | 0.0264 | 0.1093 | 0.1093 |
Leishmania major | ubiquitin-activating enzyme e1, putative | 0.0136 | 0.0451 | 0.1258 |
Trypanosoma cruzi | ubiquitin activating enzyme, putative | 0.0071 | 0.012 | 0.0105 |
Wolbachia endosymbiont of Brugia malayi | glyceraldehyde-3-phosphate dehydrogenase, GapA | 0.0264 | 0.1093 | 0.5 |
Brugia malayi | glyceraldehyde 3-phosphate dehydrogenase | 0.0082 | 0.0177 | 0.0087 |
Echinococcus granulosus | NEDD8 activating enzyme E1 regulatory subunit | 0.0108 | 0.0308 | 0.022 |
Trypanosoma brucei | adenosine kinase, putative | 0.0171 | 0.0626 | 0.1867 |
Brugia malayi | Nucleoside transporter family protein | 0.0238 | 0.0962 | 0.088 |
Trypanosoma cruzi | Ubiquitin-like modifier-activating enzyme ATG7, putative | 0.0071 | 0.012 | 0.0105 |
Echinococcus multilocularis | ubiquitin modifier activating enzyme 1 | 0.0204 | 0.079 | 0.0707 |
Trypanosoma cruzi | E1-like ubiquitin-activating enzyme, putative | 0.0071 | 0.012 | 0.0105 |
Loa Loa (eye worm) | hypothetical protein | 0.0171 | 0.0626 | 0.0618 |
Trypanosoma cruzi | ubiquitin-activating enzyme-like protein | 0.0071 | 0.012 | 0.0105 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain, putative | 0.0082 | 0.0177 | 0.0301 |
Trypanosoma cruzi | ubiquitin activating enzyme, putative | 0.0071 | 0.012 | 0.0105 |
Trypanosoma cruzi | ubiquitin-activating enzyme, putative | 0.0071 | 0.012 | 0.0105 |
Onchocerca volvulus | Equilibrative nucleoside transporter, putative homolog | 0.0238 | 0.0962 | 1 |
Entamoeba histolytica | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.0264 | 0.1093 | 0.1012 |
Entamoeba histolytica | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.0264 | 0.1093 | 0.1012 |
Echinococcus multilocularis | NEDD8 activating enzyme E1 regulatory subunit | 0.0108 | 0.0308 | 0.022 |
Plasmodium falciparum | ubiquitin-activating enzyme | 0.0081 | 0.0174 | 0.019 |
Loa Loa (eye worm) | ubiquitin-activating enzyme 5 | 0.0071 | 0.012 | 0.0112 |
Echinococcus granulosus | glyceraldehyde 3 phosphate dehydrogenase | 0.0264 | 0.1093 | 0.1012 |
Trypanosoma brucei | glyceraldehyde 3-phosphate dehydrogenase, cytosolic | 0.0264 | 0.1093 | 0.3493 |
Mycobacterium ulcerans | glyceraldehyde 3-phosphate dehydrogenase Gap | 0.0264 | 0.1093 | 0.4037 |
Plasmodium vivax | SUMO-activating enzyme subunit 2, putative | 0.0081 | 0.0174 | 0.019 |
Entamoeba histolytica | ubiquitin-activating enzyme, putative | 0.2034 | 1 | 1 |
Trypanosoma brucei | glyceraldehyde 3-phosphate dehydrogenase, glycosomal | 0.0264 | 0.1093 | 0.3493 |
Giardia lamblia | Ubiquitin-conjugating enzyme E1 | 0.0136 | 0.0451 | 0.3402 |
Schistosoma mansoni | glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) | 0.0264 | 0.1093 | 0.1093 |
Plasmodium vivax | ubiquitin-activating enzyme E1C, putative | 0.0635 | 0.2962 | 1 |
Echinococcus multilocularis | glyceraldehyde 3 phosphate dehydrogenase | 0.0173 | 0.0635 | 0.055 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative | 0.0264 | 0.1093 | 0.3493 |
Mycobacterium leprae | Probable glyceraldehyde 3-phosphate dehydrogenase Gap (GAPDH) | 0.0091 | 0.0224 | 1 |
Toxoplasma gondii | NEDD8-activating enzyme E1 catalytic subunit | 0.2034 | 1 | 1 |
Schistosoma mansoni | ubiquitin-activating enzyme E1 | 0.0176 | 0.0648 | 0.0648 |
Trichomonas vaginalis | equilibrative nucleoside transporter, putative | 0.0238 | 0.0962 | 0.1196 |
Plasmodium vivax | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.0264 | 0.1093 | 0.3424 |
Loa Loa (eye worm) | hypothetical protein | 0.0238 | 0.0962 | 0.0954 |
Schistosoma mansoni | sumo-1-activating enzyme E1a | 0.0117 | 0.0355 | 0.0355 |
Mycobacterium ulcerans | bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase | 0.055 | 0.2531 | 1 |
Brugia malayi | Glyceraldehyde 3-phosphate dehydrogenase | 0.0091 | 0.0223 | 0.0134 |
Trypanosoma cruzi | ubiquitin activating enzyme, putative | 0.0635 | 0.2962 | 1 |
Trypanosoma cruzi | ubiquitin-activating enzyme E1, putative | 0.0136 | 0.0451 | 0.1258 |
Echinococcus multilocularis | SUMO activating enzyme subunit 1 | 0.0117 | 0.0355 | 0.0267 |
Plasmodium falciparum | NEDD8-activating enzyme E1 catalytic subunit, putative | 0.0635 | 0.2962 | 1 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain, putative | 0.0082 | 0.0177 | 0.0301 |
Echinococcus multilocularis | equilibrative nucleoside transporter protein | 0.0238 | 0.0962 | 0.088 |
Entamoeba histolytica | autophagy protein apg7, putative | 0.0071 | 0.012 | 0.003 |
Brugia malayi | MoeZ/MoeB domain containing protein | 0.0071 | 0.012 | 0.003 |
Entamoeba histolytica | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.0264 | 0.1093 | 0.1012 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0264 | 0.1093 | 0.1383 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0264 | 0.1093 | 0.3493 |
Brugia malayi | hypothetical protein | 0.0238 | 0.0962 | 0.088 |
Loa Loa (eye worm) | ube1-prov protein | 0.0204 | 0.079 | 0.0782 |
Entamoeba histolytica | ubiquitin-activating enzyme, putative | 0.0071 | 0.012 | 0.003 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0264 | 0.1093 | 0.1383 |
Schistosoma mansoni | clathrin coat associated protein ap-50 | 0.0149 | 0.0513 | 0.0513 |
Leishmania major | glyceraldehyde 3-phosphate dehydrogenase, glycosomal | 0.0264 | 0.1093 | 0.3493 |
Loa Loa (eye worm) | hypothetical protein | 0.0238 | 0.0962 | 0.0954 |
Entamoeba histolytica | nucleoside transporter, putative | 0.0238 | 0.0962 | 0.088 |
Leishmania major | ubiquitin activating enzyme, putative | 0.0071 | 0.012 | 0.0105 |
Loa Loa (eye worm) | glyceraldehyde-3-phosphate dehydrogenase | 0.0182 | 0.0682 | 0.0674 |
Trypanosoma cruzi | ubiquitin-activating enzyme, putative | 0.0071 | 0.012 | 0.0105 |
Schistosoma mansoni | ubiquitin-activating enzyme E1b | 0.0071 | 0.012 | 0.012 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0065 | 0.009 | 0.0082 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0264 | 0.1093 | 0.3493 |
Leishmania major | ubiquitin-activating enzyme e1, putative | 0.0114 | 0.0338 | 0.0865 |
Entamoeba histolytica | ubiquitin-activating enzyme, putative | 0.0204 | 0.079 | 0.0707 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0173 | 0.0635 | 0.0732 |
Trichomonas vaginalis | ubiquitin-activating enzyme E1, putative | 0.0081 | 0.0174 | 0.0077 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0091 | 0.0223 | 0.0146 |
Schistosoma mansoni | glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) | 0.0264 | 0.1093 | 0.1093 |
Loa Loa (eye worm) | ThiF family protein | 0.0081 | 0.0174 | 0.0166 |
Trichomonas vaginalis | ubiquitin-activating enzyme E1, putative | 0.0081 | 0.0174 | 0.0077 |
Trypanosoma brucei | ubiquitin-activating enzyme E1, putative | 0.0071 | 0.012 | 0.0105 |
Trypanosoma cruzi | ubiquitin activating enzyme, putative | 0.0635 | 0.2962 | 1 |
Entamoeba histolytica | ubiquitin-activating enzyme, putative | 0.0081 | 0.0174 | 0.0085 |
Leishmania major | ubiquitin activating enzyme, putative | 0.0635 | 0.2962 | 1 |
Schistosoma mansoni | clathrin coat associated protein ap-50 | 0.0149 | 0.0513 | 0.0513 |
Echinococcus granulosus | SUMO activating enzyme subunit 1 | 0.0117 | 0.0355 | 0.0267 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.012 | 0.0112 |
Echinococcus multilocularis | glyceraldehyde 3 phosphate dehydrogenase | 0.0264 | 0.1093 | 0.1012 |
Entamoeba histolytica | HesA/MoeB/ThiF family protein, putative | 0.0071 | 0.012 | 0.003 |
Schistosoma mansoni | ubiquitin-activating enzyme E1-related | 0.0071 | 0.012 | 0.012 |
Trypanosoma cruzi | Ubiquitin-like modifier-activating enzyme ATG7, putative | 0.0071 | 0.012 | 0.0105 |
Schistosoma mansoni | glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) | 0.0264 | 0.1093 | 0.1093 |
Brugia malayi | CG1749-PA | 0.0071 | 0.012 | 0.003 |
Echinococcus granulosus | sumo-activating enzyme subunit 2 | 0.0071 | 0.012 | 0.003 |
Trypanosoma brucei | Ubiquitin-like modifier-activating enzyme ATG7, putative | 0.0071 | 0.012 | 0.0105 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0082 | 0.0177 | 0.0301 |
Trypanosoma cruzi | E1-like ubiquitin-activating enzyme, putative | 0.0071 | 0.012 | 0.0105 |
Giardia lamblia | Glyceraldehyde 3-phosphate dehydrogenase | 0.0173 | 0.0634 | 0.5286 |
Trichomonas vaginalis | ubiquitin-activating enzyme E1, putative | 0.0171 | 0.0626 | 0.0719 |
Plasmodium falciparum | glyceraldehyde-3-phosphate dehydrogenase | 0.0264 | 0.1093 | 0.3424 |
Entamoeba histolytica | ThiF family protein | 0.0108 | 0.0308 | 0.022 |
Trypanosoma brucei | glyceraldehyde 3-phosphate dehydrogenase, glycosomal | 0.0264 | 0.1093 | 0.3493 |
Brugia malayi | Adenosine kinase-like | 0.0171 | 0.0626 | 0.0541 |
Trypanosoma brucei | ubiquitin-activating enzyme E1, putative | 0.0071 | 0.012 | 0.0105 |
Leishmania major | hypothetical protein, conserved | 0.0108 | 0.0308 | 0.0761 |
Trichomonas vaginalis | ubiquitin-activating enzyme E1c, putative | 0.0171 | 0.0626 | 0.0719 |
Schistosoma mansoni | app binding protein | 0.0108 | 0.0308 | 0.0308 |
Trypanosoma cruzi | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.0173 | 0.0634 | 0.1896 |
Treponema pallidum | glyceraldehyde 3-phosphate dehydrogenase (gap) | 0.0264 | 0.1093 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0071 | 0.012 | 0.012 |
Loa Loa (eye worm) | hypothetical protein | 0.0117 | 0.0355 | 0.0347 |
Plasmodium falciparum | ubiquitin-activating enzyme E1 | 0.0204 | 0.079 | 0.2358 |
Echinococcus multilocularis | equilibrative nucleoside transporter 3 | 0.0197 | 0.0754 | 0.067 |
Echinococcus multilocularis | NEDD8 activating enzyme E1 catalytic subunit | 0.2034 | 1 | 1 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative | 0.0264 | 0.1093 | 0.3493 |
Trichomonas vaginalis | ubiquitin-activating enzyme E1 X, putative | 0.0109 | 0.0316 | 0.0278 |
Trypanosoma cruzi | ubiquitin-activating enzyme E1, putative | 0.0103 | 0.0284 | 0.0677 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0264 | 0.1093 | 0.1383 |
Echinococcus granulosus | equilibrative nucleoside transporter | 0.0238 | 0.0962 | 0.088 |
Echinococcus granulosus | tumor protein p63 | 0.0331 | 0.1428 | 0.135 |
Trichomonas vaginalis | ubiquitin-activating enzyme E1, putative | 0.0081 | 0.0174 | 0.0077 |
Loa Loa (eye worm) | hypothetical protein | 0.0238 | 0.0962 | 0.0954 |
Echinococcus multilocularis | ubiquitin modifier activating enzyme ATG7 | 0.0071 | 0.012 | 0.003 |
Echinococcus multilocularis | tumor protein p63 | 0.0331 | 0.1428 | 0.135 |
Leishmania major | ubiquitin-activating enzyme, putative | 0.0071 | 0.012 | 0.0105 |
Trichomonas vaginalis | ubiquitin-activating enzyme E1, putative | 0.0171 | 0.0626 | 0.0719 |
Leishmania major | adenosine kinase, putative | 0.0171 | 0.0626 | 0.1867 |
Onchocerca volvulus | 0.0152 | 0.0528 | 0.5448 | |
Loa Loa (eye worm) | glyceraldehyde 3-phosphate dehydrogenase | 0.0173 | 0.0635 | 0.0627 |
Trypanosoma brucei | adenosine kinase, putative | 0.0171 | 0.0626 | 0.1867 |
Trypanosoma brucei | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.0173 | 0.0634 | 0.1896 |
Trypanosoma cruzi | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.0173 | 0.0634 | 0.1896 |
Brugia malayi | ThiF family protein | 0.0108 | 0.0308 | 0.022 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative | 0.0082 | 0.0177 | 0.0301 |
Toxoplasma gondii | kinase, pfkB family protein | 0.0171 | 0.0626 | 0.0512 |
Echinococcus multilocularis | ubiquitin modifier activating enzyme 5 | 0.0071 | 0.012 | 0.003 |
Trypanosoma brucei | molybdopterin synthase sulphurylase protein, putative | 0.0071 | 0.012 | 0.0105 |
Leishmania major | NAD/FAD dependent dehydrogenase, putative | 0.0071 | 0.012 | 0.0105 |
Echinococcus granulosus | NEDD8 activating enzyme E1 catalytic subunit | 0.2034 | 1 | 1 |
Leishmania major | ubiquitin activating E1 enzyme, putative | 0.0071 | 0.012 | 0.0105 |
Echinococcus granulosus | glyceraldehyde 3 phosphate dehydrogenase | 0.0173 | 0.0635 | 0.055 |
Plasmodium falciparum | SUMO-activating enzyme subunit 1 | 0.0117 | 0.0355 | 0.0827 |
Echinococcus multilocularis | adenosine kinase | 0.0171 | 0.0626 | 0.0541 |
Trichomonas vaginalis | equilibrative nucleoside transporter, putative | 0.0238 | 0.0962 | 0.1196 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0264 | 0.1093 | 0.3493 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.0065 | 0.009 | 0.009 |
Echinococcus multilocularis | SUMO activating enzyme subunit 2 | 0.0071 | 0.012 | 0.003 |
Loa Loa (eye worm) | glyceraldehyde-3-phosphate dehydrogenase | 0.0182 | 0.0682 | 0.0674 |
Echinococcus granulosus | equilibrative nucleoside transporter 3 | 0.0238 | 0.0962 | 0.088 |
Schistosoma mansoni | adenosine kinase | 0.0171 | 0.0626 | 0.0626 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.012 | 0.0112 |
Echinococcus granulosus | adenosine kinase | 0.0171 | 0.0626 | 0.0541 |
Toxoplasma gondii | glyceraldehyde-3-phosphate dehydrogenase GAPDH2 | 0.0264 | 0.1093 | 0.0985 |
Echinococcus granulosus | glyceraldehyde 3 phosphate dehydrogenase | 0.0264 | 0.1093 | 0.1012 |
Entamoeba histolytica | ubiquitin-activating enzyme E1 1, putative | 0.0171 | 0.0626 | 0.0541 |
Echinococcus multilocularis | adenylyltransferase and sulfurtransferase | 0.0071 | 0.012 | 0.003 |
Brugia malayi | ube1-prov protein | 0.0204 | 0.079 | 0.0707 |
Trichomonas vaginalis | ubiquitin-activating enzyme E1, putative | 0.0108 | 0.0308 | 0.0268 |
Echinococcus granulosus | ubiquitin modifier activating enzyme 6 | 0.0204 | 0.079 | 0.0707 |
Toxoplasma gondii | glyceraldehyde-3-phosphate dehydrogenase GAPDH1 | 0.0264 | 0.1093 | 0.0985 |
Mycobacterium tuberculosis | Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase | 0.055 | 0.2531 | 1 |
Schistosoma mansoni | ubiquitin-activating enzyme E1 | 0.0071 | 0.012 | 0.012 |
Trypanosoma cruzi | molybdopterin synthase sulphurylase-like protein, putative | 0.0071 | 0.012 | 0.0105 |
Echinococcus granulosus | ubiquitin modifier activating enzyme 5 | 0.0071 | 0.012 | 0.003 |
Leishmania major | glyceraldehyde-3-phosphate dehydrogenase-like protein | 0.0173 | 0.0634 | 0.1896 |
Trypanosoma brucei | ubiquitin-activating enzyme E1, putative | 0.0114 | 0.0338 | 0.0865 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative | 0.0082 | 0.0177 | 0.0301 |
Trypanosoma cruzi | ubiquitin-activating enzyme E1, putative | 0.0136 | 0.0451 | 0.1258 |
Trichomonas vaginalis | ubiquitin-activating enzyme E1, putative | 0.0108 | 0.0308 | 0.0268 |
Toxoplasma gondii | ThiF family protein | 0.0108 | 0.0308 | 0.0191 |
Trichomonas vaginalis | equilibrative nucleoside transporter, putative | 0.0238 | 0.0962 | 0.1196 |
Giardia lamblia | Hypothetical protein | 0.0238 | 0.0962 | 0.8652 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0264 | 0.1093 | 0.1383 |
Leishmania major | glyceraldehyde 3-phosphate dehydrogenase, glycosomal | 0.0264 | 0.1093 | 0.3493 |
Loa Loa (eye worm) | hypothetical protein | 0.0173 | 0.0635 | 0.0627 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative | 0.0264 | 0.1093 | 0.3493 |
Brugia malayi | E1-like protein-activating enzyme Gsa7p/Apg7p containing protein | 0.0071 | 0.012 | 0.003 |
Trypanosoma brucei | ubiquitin-activating enzyme E1, putative | 0.0136 | 0.0451 | 0.1258 |
Toxoplasma gondii | hypothetical protein | 0.0117 | 0.0355 | 0.0238 |
Plasmodium vivax | ubiquitin-activating enzyme, putative | 0.0081 | 0.0174 | 0.019 |
Trichomonas vaginalis | ubiquitin-activating enzyme E1, putative | 0.0105 | 0.0295 | 0.0248 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0264 | 0.1093 | 0.3493 |
Trypanosoma brucei | ubiquitin activating enzyme, putative | 0.0071 | 0.012 | 0.0105 |
Echinococcus multilocularis | glyceraldehyde 3 phosphate dehydrogenase | 0.0264 | 0.1093 | 0.1012 |
Trypanosoma brucei | NEDD8-activating enzyme E1 regulatory subunit, putative | 0.0108 | 0.0308 | 0.0761 |
Brugia malayi | Glyceraldehyde 3-phosphate dehydrogenase | 0.0264 | 0.1093 | 0.1012 |
Trypanosoma cruzi | NEDD8-activating enzyme E1 regulatory subunit, putative | 0.0108 | 0.0308 | 0.0761 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0264 | 0.1093 | 0.1383 |
Echinococcus granulosus | adenylyltransferase and sulfurtransferase | 0.0071 | 0.012 | 0.003 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
GI50 (functional) | -5.433 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HOP-92 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.045 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.04 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.024 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MALME-3M Melanoma cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.993 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.976 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.92 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.872 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MDA-N Breast cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.868 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.812 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the DU-145 Prostate cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.809 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-5 Melanoma cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.