Detailed information for compound 1811551

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 377.837 | Formula: C20H21ClFNO3
  • H donors: 0 H acceptors: 1 LogP: 4.29 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: C=CCOC1N(C(=O)C2=C1CCCC2)c1cc(OCC=C)c(cc1F)Cl
  • InChi: 1S/C20H21ClFNO3/c1-3-9-25-18-12-17(16(22)11-15(18)21)23-19(24)13-7-5-6-8-14(13)20(23)26-10-4-2/h3-4,11-12,20H,1-2,5-10H2
  • InChiKey: WWQZMPJWEOBPBH-UHFFFAOYSA-N  


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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis Immunoglobulin 0.0069 0.0335 0.0335
Schistosoma mansoni serine/threonine protein kinase 0.0167 0.1337 0.1337
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0061 0.026 0.026
Loa Loa (eye worm) cyclin domain-containing protein 0.0085 0.0506 0.0506
Loa Loa (eye worm) hypothetical protein 0.007 0.0346 0.0346
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0167 0.1337 0.1337
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0054 0.0179 0.0179
Echinococcus multilocularis oligomeric golgi complex subunit 3 0.0085 0.0506 0.0506
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0098 0.0633 0.0633
Loa Loa (eye worm) hypothetical protein 0.007 0.0346 0.0346
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.0506 0.0874
Brugia malayi protein kinase C II. 0.0388 0.3603 0.3603
Entamoeba histolytica protein kinase domain containing protein 0.0061 0.026 0.0416
Schistosoma mansoni tyrosine kinase 0.0054 0.0179 0.0179
Trichomonas vaginalis CMGC family protein kinase 0.0065 0.0291 0.0458
Brugia malayi Protein kinase domain containing protein 0.0081 0.0463 0.0463
Schistosoma mansoni diacylglycerol kinase theta 0.007 0.0346 0.0346
Schistosoma mansoni unc-13 (munc13) 0.0076 0.0413 0.0413
Echinococcus granulosus serine/threonine protein kinase 0.0149 0.1159 0.1159
Trypanosoma cruzi CYC2-like cyclin, putative 0.0545 0.5208 1
Loa Loa (eye worm) TK protein kinase 0.0047 0.0113 0.0113
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0065 0.0291 0.0063
Echinococcus granulosus tyrosine protein kinase ABL1 0.0219 0.1877 0.1877
Onchocerca volvulus Protein CNPPD1 homolog 0.0085 0.0506 0.0971
Echinococcus granulosus nervana 2 0.0129 0.0953 0.0953
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0065 0.0291 0.013
Brugia malayi Fibronectin type III domain containing protein 0.0069 0.0335 0.0335
Trichomonas vaginalis AGC family protein kinase 0.0304 0.2747 0.5224
Loa Loa (eye worm) TK/ABL protein kinase 0.0219 0.1877 0.1877
Brugia malayi hypothetical protein 0.0069 0.0335 0.0335
Trichomonas vaginalis cyclin B, putative 0.0545 0.5208 1
Plasmodium falciparum protein kinase 5 0.0098 0.0633 0.1242
Echinococcus granulosus cyclin 0.0085 0.0506 0.0506
Trypanosoma cruzi Protein kinase B 0.0149 0.1159 0.1816
Schistosoma mansoni cyclin B 0.0545 0.5208 0.5208
Echinococcus multilocularis roundabout 2 0.0105 0.0704 0.0704
Echinococcus granulosus Diacylglycerol kinase theta 0.007 0.0346 0.0346
Brugia malayi Pleckstrin Homology Domain 0.0078 0.0434 0.0434
Brugia malayi Tyrosine-protein kinase abl-1 0.0124 0.0899 0.0899
Onchocerca volvulus 0.0206 0.1743 0.3346
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0141 0.1071 0.1638
Echinococcus multilocularis Cyclin L1 0.0085 0.0506 0.0506
Schistosoma mansoni serine/threonine protein kinase 0.0081 0.0463 0.0463
Onchocerca volvulus 0.0085 0.0506 0.0971
Echinococcus multilocularis Immunoglobulin 0.0069 0.0335 0.0335
Loa Loa (eye worm) Ras association domain family 1 isoform A 0.007 0.0346 0.0346
Echinococcus multilocularis cyclin A3 4 0.0085 0.0506 0.0506
Trichomonas vaginalis cyclin B, putative 0.0354 0.3257 0.6213
Trichomonas vaginalis AGC family protein kinase 0.0304 0.2747 0.5224
Schistosoma mansoni hypothetical protein 0.0085 0.0506 0.0506
Trichomonas vaginalis AGC family protein kinase 0.0197 0.1644 0.3083
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0098 0.0633 0.0752
Echinococcus granulosus cyclin b3 0.0354 0.3257 0.3257
Echinococcus granulosus cyclin y 0.0085 0.0506 0.0506
Entamoeba histolytica phosphatidylinositol 3-kinase 1, putative 0.0092 0.0577 0.1029
Trypanosoma cruzi mitotic cyclin, putative 0.0085 0.0506 0.0496
Trichomonas vaginalis cyclin B, putative 0.0545 0.5208 1
Giardia lamblia G2/mitotic-specific cyclin B 0.0545 0.5208 1
Loa Loa (eye worm) hypothetical protein 0.029 0.2598 0.2598
Entamoeba histolytica protein kinase, putative 0.0304 0.2747 0.5233
Entamoeba histolytica cell division protein kinase 2, putative 0.0098 0.0633 0.1137
Toxoplasma gondii hypothetical protein 0.0085 0.0506 0.1024
Echinococcus multilocularis cyclin t1 0.0085 0.0506 0.0506
Leishmania major cyclin 0.0545 0.5208 1
Trichomonas vaginalis cyclins, putative 0.0276 0.2457 0.4661
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0296 0.2659 0.2659
Echinococcus granulosus neuroglian 0.0091 0.0562 0.0562
Brugia malayi protein kinase C3,putative 0.0168 0.135 0.135
Schistosoma mansoni serine/threonine protein kinase 0.0167 0.1337 0.1337
Schistosoma mansoni serine/threonine protein kinase 0.0167 0.1337 0.1337
Brugia malayi Hr1 repeat family protein 0.0167 0.1337 0.1337
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0388 0.3603 0.3603
Plasmodium falciparum cyclin 1 0.0085 0.0506 0.082
Toxoplasma gondii hypothetical protein 0.0269 0.2382 0.8845
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0069 0.0335 0.0335
Schistosoma mansoni diacylglycerol kinase theta 0.007 0.0346 0.0346
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0061 0.026 0.026
Schistosoma mansoni cyclin d 0.1013 1 1
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0054 0.0179 0.0179
Echinococcus granulosus cyclin G2 0.0085 0.0506 0.0506
Trichomonas vaginalis cyclin B3, putative 0.0085 0.0506 0.0874
Schistosoma mansoni vesicular amine transporter 0.0069 0.0335 0.0335
Schistosoma mansoni tyrosine kinase 0.0453 0.4269 0.4269
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0081 0.0463 0.0463
Trichomonas vaginalis cyclin B, putative 0.0545 0.5208 1
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0054 0.0179 0.0179
Schistosoma mansoni serine/threonine protein kinase 0.02 0.168 0.168
Trichomonas vaginalis CMGC family protein kinase 0.0061 0.026 0.0397
Echinococcus granulosus serine:threonine protein kinase N2 0.0167 0.1337 0.1337
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0065 0.0301 0.0476
Brugia malayi Immunoglobulin I-set domain containing protein 0.0069 0.0335 0.0335
Brugia malayi Protein kinase domain containing protein 0.0167 0.1337 0.1337
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0065 0.0291 0.0063
Trichomonas vaginalis cyclin B, putative 0.0085 0.0506 0.0874
Echinococcus granulosus cyclin dependent kinase 6 0.0174 0.141 0.141
Echinococcus multilocularis cyclin dependent kinase 1 0.0098 0.0633 0.0633
Echinococcus multilocularis cyclin B 0.0545 0.5208 0.5208
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0494 0.4694 0.4694
Loa Loa (eye worm) hypothetical protein 0.0206 0.1743 0.1743
Echinococcus multilocularis cyclin dependent kinase 5 0.0098 0.0633 0.0633
Echinococcus granulosus oligomeric golgi complex subunit 3 0.0085 0.0506 0.0506
Loa Loa (eye worm) hypothetical protein 0.007 0.0346 0.0346
Schistosoma mansoni serine/threonine protein kinase 0.0098 0.0633 0.0633
Trypanosoma brucei protein kinase, putative 0.0065 0.0291 0.0063
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0076 0.0413 0.0413
Echinococcus granulosus cyclin y 0.0085 0.0506 0.0506
Giardia lamblia Kinase, CMGC GSK 0.0061 0.026 0.0311
Echinococcus granulosus cyclins 0.0354 0.3257 0.3257
Trichomonas vaginalis cyclins, putative 0.0545 0.5208 1
Giardia lamblia Kinase, CMGC MAPK 0.0065 0.0291 0.0372
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0048 0.0118 0.0118
Echinococcus multilocularis raf serine:threonine protein kinase 0.0082 0.047 0.047
Echinococcus granulosus tyrosine protein kinase Lyn 0.0065 0.0297 0.0297
Echinococcus multilocularis mitogen activated protein kinase 11 0.0407 0.3795 0.3795
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0061 0.026 0.026
Echinococcus multilocularis mitogen activated protein kinase 3 0.0065 0.0291 0.0291
Echinococcus granulosus cyclin A3 4 0.0085 0.0506 0.0506
Echinococcus multilocularis serine:threonine protein kinase N2 0.0167 0.1337 0.1337
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.02 0.168 0.168
Entamoeba histolytica cyclin C, putative 0.0085 0.0506 0.0891
Schistosoma mansoni serine/threonine protein kinase 0.0098 0.0633 0.0633
Brugia malayi protein-tyrosine kinase 0.0047 0.0113 0.0113
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0054 0.0179 0.0179
Schistosoma mansoni serine/threonine protein kinase 0.0081 0.0463 0.0463
Entamoeba histolytica protein kinase, putative 0.0167 0.1337 0.2501
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0095 0.0606 0.0606
Trypanosoma brucei mitotic cyclin 0.0085 0.0506 0.0496
Brugia malayi SRC-1 0.0054 0.0179 0.0179
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0054 0.0179 0.0179
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0167 0.1337 0.1337
Trypanosoma cruzi cyclin 9, putative 0.0085 0.0506 0.0496
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0407 0.3795 0.3795
Toxoplasma gondii cyclin domain protein, cyclin H family protein 0.0085 0.0506 0.1024
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0076 0.0413 0.0413
Echinococcus multilocularis mitogen activated protein kinase 0.0065 0.0291 0.0291
Echinococcus granulosus cyclin dependent kinase 5 0.0098 0.0633 0.0633
Schistosoma mansoni cyclin B3 0.0583 0.5599 0.5599
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0407 0.3795 0.7143
Onchocerca volvulus 0.0076 0.0413 0.0793
Giardia lamblia Hypothetical protein 0.0354 0.3257 0.6179
Echinococcus multilocularis cyclin dependent kinase 0.0098 0.0633 0.0633
Onchocerca volvulus Cyclin L homolog 0.0085 0.0506 0.0971
Echinococcus multilocularis cyclin k 0.0085 0.0506 0.0506
Echinococcus granulosus cyclin k 0.0085 0.0506 0.0506
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0085 0.0506 0.082
Toxoplasma gondii cyclin 4, putative 0.0085 0.0506 0.1024
Entamoeba histolytica cyclin, domain containing protein 0.0085 0.0506 0.0891
Trypanosoma cruzi cdc2-related kinase 3 0.0098 0.0633 0.0752
Brugia malayi C1-like domain containing protein 0.0209 0.1772 0.1772
Entamoeba histolytica diacylglycerol kinase, putative 0.007 0.0346 0.0581
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0219 0.1877 0.1877
Schistosoma mansoni cyclin G 0.0085 0.0506 0.0506
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.0179 0.1465 0.1465
Echinococcus granulosus tyrosine protein kinase Blk 0.0047 0.0113 0.0113
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0095 0.0606 0.1068
Echinococcus multilocularis unc 13 (munc13) 0.0076 0.0413 0.0413
Entamoeba histolytica protein kinase, putative 0.0304 0.2747 0.5233
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0453 0.4269 0.4269
Echinococcus granulosus twitchin 0.0102 0.068 0.068
Echinococcus multilocularis tyrosine protein kinase Abl 0.0102 0.0674 0.0674
Entamoeba histolytica protein kinase, putative 0.0296 0.2659 0.5062
Echinococcus granulosus protein kinase c iota type 0.0323 0.2938 0.2938
Plasmodium falciparum cyclin dependent kinase binding protein, putative 0.0085 0.0506 0.082
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0038 0.0025 0.0025
Schistosoma mansoni serine/threonine-protein kinase 0.0149 0.1159 0.1159
Brugia malayi Cyclin, N-terminal domain containing protein 0.0545 0.5208 0.5208
Schistosoma mansoni hypothetical protein 0.007 0.0346 0.0346
Trypanosoma cruzi mitotic cyclin, putative 0.0085 0.0506 0.0496
Echinococcus granulosus Glutaredoxin protein 5 0.0129 0.0953 0.0953
Echinococcus multilocularis tyrosine protein kinase Srms 0.0047 0.0113 0.0113
Echinococcus multilocularis mitogen activated protein kinase 14 0.0407 0.3795 0.3795
Loa Loa (eye worm) hypothetical protein 0.0194 0.1617 0.1617
Echinococcus granulosus NDR protein kinase 0.0167 0.1337 0.1337
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0069 0.0335 0.0335
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0095 0.0606 0.1068
Toxoplasma gondii cyclin dependent kinase binding protein 0.0085 0.0506 0.1024
Loa Loa (eye worm) hypothetical protein 0.0545 0.5208 0.5208
Schistosoma mansoni serine/threonine-protein kinase 0.0149 0.1159 0.1159
Echinococcus granulosus serine:threonine protein kinase N2 0.0156 0.1232 0.1232
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.0506 0.0874
Loa Loa (eye worm) hypothetical protein 0.0083 0.0476 0.0476
Echinococcus multilocularis Glutaredoxin protein 5 0.0129 0.0953 0.0953
Loa Loa (eye worm) hypothetical protein 0.0927 0.9125 0.9125
Entamoeba histolytica PH domain containing protein kinase, putative 0.0149 0.1159 0.2156
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0176 0.1438 0.2683
Loa Loa (eye worm) CAMK/CAMKL/NUAK protein kinase 0.0484 0.4592 0.4592
Entamoeba histolytica protein kinase, putative 0.0061 0.026 0.0416
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0065 0.0291 0.0063
Onchocerca volvulus 0.029 0.2598 0.4988
Trypanosoma brucei cdc2-related kinase 1 0.0098 0.0633 0.0752
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0407 0.3795 0.7143
Loa Loa (eye worm) hypothetical protein 0.0089 0.0541 0.0541
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0047 0.0113 0.0113
Echinococcus multilocularis neuroglian 0.0091 0.0562 0.0562
Trichomonas vaginalis cyclin A, putative 0.0085 0.0506 0.0874
Brugia malayi Cyclin, N-terminal domain containing protein 0.0085 0.0506 0.0506
Echinococcus multilocularis mitogen activated protein kinase 14 0.0407 0.3795 0.3795
Echinococcus granulosus cyclin dependent kinase 1 0.0098 0.0633 0.0633
Loa Loa (eye worm) hypothetical protein 0.0105 0.0704 0.0704
Trichomonas vaginalis cyclins, putative 0.0354 0.3257 0.6213
Echinococcus granulosus cyclins 0.0354 0.3257 0.3257
Brugia malayi Immunoglobulin I-set domain containing protein 0.0475 0.4497 0.4497
Echinococcus granulosus RNA directed DNA polymerase 0.0124 0.0903 0.0903
Brugia malayi Cyclin, N-terminal domain containing protein 0.0085 0.0506 0.0506
Loa Loa (eye worm) hypothetical protein 0.0456 0.4304 0.4304
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0095 0.0606 0.0699
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0095 0.0606 0.1068
Entamoeba histolytica protein kinase domain containing protein 0.0061 0.026 0.0416
Onchocerca volvulus Cyclin L homolog 0.0085 0.0506 0.0971
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0068 0.033 0.033
Trichomonas vaginalis cyclin D, putative 0.0354 0.3257 0.6213
Brugia malayi Cyclin, N-terminal domain containing protein 0.0583 0.5599 0.5599
Schistosoma mansoni tyrosine kinase 0.0048 0.0125 0.0125
Trypanosoma cruzi hypothetical protein, conserved 0.0085 0.0506 0.0496
Trichomonas vaginalis AGC family protein kinase 0.0188 0.1556 0.2911
Brugia malayi Protein kinase domain containing protein 0.0188 0.1556 0.1556
Schistosoma mansoni vav2 0.0085 0.0501 0.0501
Brugia malayi map kinase activated protein kinase protein 2 0.02 0.168 0.168
Echinococcus multilocularis cyclin G2 0.0085 0.0506 0.0506
Schistosoma mansoni serine/threonine kinase 0.0167 0.1337 0.1337
Echinococcus granulosus N chimaerin 0.0076 0.0413 0.0413
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0209 0.1772 0.1772
Schistosoma mansoni g1/s-specific cyclin C 0.0085 0.0506 0.0506
Trichomonas vaginalis cyclin B3, putative 0.0354 0.3257 0.6213
Giardia lamblia Cyclin fold protein 1, putative 0.0085 0.0506 0.0792
Brugia malayi hypothetical protein 0.0085 0.0506 0.0506
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0098 0.0633 0.0633
Echinococcus multilocularis protein kinase c eta type 0.007 0.0346 0.0346
Echinococcus multilocularis Rac GTPase activating protein 1 0.007 0.0346 0.0346
Echinococcus multilocularis mitogen activated protein kinase 11 0.0407 0.3795 0.3795
Loa Loa (eye worm) hypothetical protein 0.007 0.0346 0.0346
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0054 0.0179 0.0179
Echinococcus granulosus mitogen activated protein kinase 3 0.0065 0.0291 0.0291
Echinococcus multilocularis protein kinase shaggy 0.0061 0.026 0.026
Echinococcus granulosus defective proboscis extension response 0.0069 0.0335 0.0335
Brugia malayi Cyclin, N-terminal domain containing protein 0.0085 0.0506 0.0506
Echinococcus granulosus mitogen activated protein kinase 11 0.0407 0.3795 0.3795
Loa Loa (eye worm) hypothetical protein 0.0124 0.0903 0.0903
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0076 0.0413 0.0413
Loa Loa (eye worm) AGC/PKN protein kinase 0.0167 0.1337 0.1337
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0141 0.1071 0.1071
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.02 0.168 0.168
Schistosoma mansoni serine/threonine protein kinase 0.0065 0.0291 0.0291
Loa Loa (eye worm) cyclin C 0.0085 0.0506 0.0506
Trypanosoma cruzi cdc2-related kinase 3 0.0098 0.0633 0.0752
Brugia malayi Tyrosine-protein kinase abl-1 0.0102 0.0674 0.0674
Echinococcus granulosus cyclin B 0.0545 0.5208 0.5208
Trichomonas vaginalis CMGC family protein kinase 0.0061 0.026 0.0397
Toxoplasma gondii cyclin, N-terminal domain-containing protein 0.0085 0.0506 0.1024
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.0506 0.0874
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0129 0.0953 0.0953
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0095 0.06 0.06
Brugia malayi Protein kinase domain containing protein 0.0098 0.0633 0.0633
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0188 0.1556 0.1556
Echinococcus granulosus Cyclin L1 0.0085 0.0506 0.0506
Trichomonas vaginalis cyclins, putative 0.0545 0.5208 1
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0076 0.0413 0.0413
Brugia malayi Protein kinase c protein 2 0.0212 0.1803 0.1803
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0065 0.0291 0.0291
Schistosoma mansoni protein kinase C mu 0.007 0.0346 0.0346
Loa Loa (eye worm) cyclin domain-containing protein 0.0085 0.0506 0.0506
Echinococcus multilocularis serine:threonine protein kinase N2 0.0312 0.2821 0.2821
Trichomonas vaginalis cyclin B3, putative 0.0085 0.0506 0.0874
Loa Loa (eye worm) hypothetical protein 0.0069 0.0335 0.0335
Brugia malayi Stress-activated protein kinase jnk-1 0.0494 0.4694 0.4694
Plasmodium vivax hypothetical protein, conserved 0.0085 0.0506 0.3031
Schistosoma mansoni serine/threonine protein kinase 0.0167 0.1337 0.1337
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0065 0.0291 0.0063
Brugia malayi MAP kinase sur-1 0.0065 0.0291 0.0291
Trichomonas vaginalis CMGC family protein kinase 0.0098 0.0633 0.112
Onchocerca volvulus 0.0545 0.5208 1
Schistosoma mansoni cell adhesion molecule 0.0083 0.0476 0.0476
Echinococcus multilocularis RNA directed DNA polymerase 0.0124 0.0903 0.0903
Giardia lamblia Kinase, CMGC CDK 0.0098 0.0633 0.104
Trypanosoma brucei mitotic cyclin 6 0.0545 0.5208 1
Loa Loa (eye worm) hypothetical protein 0.0069 0.0335 0.0335
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0167 0.1337 0.1337
Loa Loa (eye worm) AGC/AKT protein kinase 0.0304 0.2747 0.2747
Echinococcus granulosus tyrosine kinase 0.0047 0.0113 0.0113
Loa Loa (eye worm) variant SH3 domain-containing protein 0.007 0.0346 0.0346
Trichomonas vaginalis AGC family protein kinase 0.0304 0.2747 0.5224
Giardia lamblia Hypothetical protein 0.0085 0.0506 0.0792
Schistosoma mansoni serine/threonine protein kinase 0.0082 0.047 0.047
Schistosoma mansoni serine/threonine protein kinase 0.0367 0.3391 0.3391
Schistosoma mansoni tyrosine kinase 0.0213 0.1809 0.1809
Trichomonas vaginalis cyclin D, putative 0.0085 0.0506 0.0874
Echinococcus granulosus protein kinase C gamma type 0.0297 0.2676 0.2676
Trypanosoma brucei rac serine-threonine kinase, putative 0.0304 0.2747 0.5026
Leishmania major CYC2-like cyclin, putative,cyclin 6, putative 0.0545 0.5208 1
Loa Loa (eye worm) RasGEF domain-containing protein 0.007 0.0346 0.0346
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0065 0.0301 0.0476
Schistosoma mansoni cyclin k 0.0085 0.0506 0.0506
Trypanosoma cruzi cdc2-related kinase 1 0.0098 0.0633 0.0752
Schistosoma mansoni protein kinase C mu 0.0209 0.1772 0.1772
Trichomonas vaginalis cyclin B, putative 0.0085 0.0506 0.0874
Echinococcus granulosus cyclin dependent kinase 0.0098 0.0633 0.0633
Trichomonas vaginalis cyclins, putative 0.0085 0.0506 0.0874
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0167 0.1337 0.1337
Loa Loa (eye worm) cyclin fold protein 1 variant b 0.0085 0.0506 0.0506
Schistosoma mansoni hypothetical protein 0.0085 0.0506 0.0506
Trypanosoma cruzi cdc2-related kinase 1 0.0098 0.0633 0.0752
Entamoeba histolytica cell division protein kinase 2, putative 0.0098 0.0633 0.1137
Plasmodium vivax cyclin homologue, putative 0.0085 0.0506 0.3031
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0141 0.1071 0.1071
Echinococcus granulosus G1:S specific cyclin D1 0.1013 1 1
Brugia malayi Protein kinase domain containing protein 0.0304 0.2747 0.2747
Entamoeba histolytica hypothetical protein 0.0076 0.0407 0.0699
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0174 0.1415 0.1415
Echinococcus granulosus cyclins 0.0354 0.3257 0.3257
Brugia malayi diacylglycerol kinase 0.007 0.0346 0.0346
Trypanosoma cruzi cyclin, putative 0.0545 0.5208 1
Brugia malayi Cyclin, N-terminal domain containing protein 0.0545 0.5208 0.5208
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.0179 0.1465 0.1465
Loa Loa (eye worm) hypothetical protein 0.0062 0.0262 0.0262
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0065 0.0291 0.0063
Loa Loa (eye worm) cyclin domain-containing protein 0.0583 0.5599 0.5599
Loa Loa (eye worm) hypothetical protein 0.036 0.3313 0.3313
Echinococcus multilocularis rac serine:threonine kinase 0.0149 0.1159 0.1159
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0415 0.3878 0.3878
Entamoeba histolytica cyclin, putative 0.0545 0.5208 1
Entamoeba histolytica PH domain containing protein kinase, putative 0.0165 0.1321 0.2469
Entamoeba histolytica hypothetical protein 0.007 0.0346 0.0581
Echinococcus granulosus cyclin B3 1 0.0354 0.3257 0.3257
Loa Loa (eye worm) hypothetical protein 0.007 0.0346 0.0346
Schistosoma mansoni serine/threonine protein kinase 0.0174 0.141 0.141
Echinococcus multilocularis tyrosine protein kinase HCK 0.0041 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0128 0.094 0.094
Echinococcus granulosus unc 13 munc13 0.0076 0.0413 0.0413
Loa Loa (eye worm) hypothetical protein 0.029 0.2598 0.2598
Echinococcus granulosus mitogen activated protein kinase 14 0.0407 0.3795 0.3795
Echinococcus multilocularis cyclins 0.0354 0.3257 0.3257
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0095 0.0606 0.1085
Schistosoma mansoni cyclins 0.0354 0.3257 0.3257
Trichomonas vaginalis AGC family protein kinase 0.0167 0.1337 0.2487
Echinococcus multilocularis cyclin 0.0085 0.0506 0.0506
Echinococcus granulosus tyrosine protein kinase Fyn 0.0054 0.0179 0.0179
Echinococcus multilocularis myotubularin protein 13 0.0078 0.0434 0.0434
Trichomonas vaginalis CMGC family protein kinase 0.0065 0.0291 0.0458
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0167 0.1337 0.1337
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0065 0.0291 0.0063
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.0085 0.0506 0.0506
Trichomonas vaginalis CMGC family protein kinase 0.0065 0.0291 0.0458
Echinococcus multilocularis G1:S specific cyclin D1 0.1013 1 1
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0167 0.1337 0.1337
Echinococcus granulosus myotubularin protein 13 0.0078 0.0434 0.0434
Trichomonas vaginalis conserved hypothetical protein 0.0354 0.3257 0.6213
Giardia lamblia Cyclin A 0.0354 0.3257 0.6179
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0098 0.0633 0.0752
Entamoeba histolytica cyclin, domain containing protein 0.0085 0.0506 0.0891
Loa Loa (eye worm) TK protein kinase 0.0475 0.4497 0.4497
Schistosoma mansoni serine/threonine protein kinase 0.0388 0.3603 0.3603
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0098 0.0633 0.0633
Entamoeba histolytica cyclin family protein 0.0354 0.3257 0.622
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0129 0.0953 0.0953
Echinococcus multilocularis cyclin dependent kinase 1 0.0098 0.0633 0.0633
Echinococcus multilocularis cyclins 0.0354 0.3257 0.3257
Echinococcus multilocularis cdk5 and abl1 enzyme substrate 1 0.0085 0.0506 0.0506
Loa Loa (eye worm) raf kinase 0.007 0.0346 0.0346
Echinococcus multilocularis N chimaerin 0.0076 0.0413 0.0413
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0076 0.0413 0.0413
Schistosoma mansoni Cyclin fold protein 0.0085 0.0506 0.0506
Plasmodium vivax cyclin 4, putative 0.0085 0.0506 0.3031
Brugia malayi Cyclin C 0.0085 0.0506 0.0506
Toxoplasma gondii AGC kinase 0.0296 0.2659 1
Echinococcus granulosus tyrosine protein kinase Fyn 0.0054 0.0179 0.0179
Loa Loa (eye worm) hypothetical protein 0.007 0.0346 0.0346
Brugia malayi cell division control protein 2 homolog 0.0098 0.0633 0.0633
Trichomonas vaginalis cyclins, putative 0.0085 0.0506 0.0874
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0042 0.0063 0.0034
Echinococcus granulosus cyclins 0.0354 0.3257 0.3257
Schistosoma mansoni cyclin G2 0.0085 0.0506 0.0506
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0407 0.3795 0.7143
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0061 0.026 0.026
Loa Loa (eye worm) hypothetical protein 0.0086 0.0515 0.0515
Loa Loa (eye worm) cyclin domain-containing protein 0.0085 0.0506 0.0506
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0062 0.0262 0.0262
Trichomonas vaginalis cyclin D, putative 0.0354 0.3257 0.6213
Brugia malayi intracellular kinase 0.0061 0.026 0.026
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.0124 0.0903 0.0903
Loa Loa (eye worm) hypothetical protein 0.0076 0.0413 0.0413
Entamoeba histolytica PH domain containing protein kinase, putative 0.0149 0.1159 0.2156
Loa Loa (eye worm) hypothetical protein 0.0191 0.1582 0.1582
Echinococcus multilocularis cyclins 0.0354 0.3257 0.3257
Echinococcus granulosus G2:mitotic specific cyclin B3 0.0583 0.5599 0.5599
Echinococcus granulosus protein kinase c eta type 0.007 0.0346 0.0346
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0095 0.0606 0.0699
Echinococcus granulosus fibroblast growth factor receptor 4 0.0453 0.4269 0.4269
Onchocerca volvulus 0.0198 0.1654 0.3176
Echinococcus multilocularis cyclin dependent kinase 6 0.0174 0.141 0.141
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.0506 0.0874
Entamoeba histolytica protein kinase 2, putative 0.0141 0.1071 0.1985
Loa Loa (eye worm) hypothetical protein 0.0069 0.0335 0.0335
Trichomonas vaginalis cyclins, putative 0.0545 0.5208 1
Plasmodium falciparum cyclin 0.0354 0.3257 1
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0209 0.1772 0.1772
Trichomonas vaginalis CMGC family protein kinase 0.0065 0.0291 0.0458
Giardia lamblia Hypothetical protein 0.0085 0.0506 0.0792
Echinococcus multilocularis cyclins 0.0354 0.3257 0.3257
Schistosoma mansoni unc-13 (munc13) 0.0076 0.0413 0.0413
Brugia malayi Immunoglobulin I-set domain containing protein 0.0095 0.06 0.06
Schistosoma mansoni rac gtpase activating protein 0.007 0.0346 0.0346
Echinococcus multilocularis nervana 2 0.0129 0.0953 0.0953
Trichomonas vaginalis cyclins, putative 0.0545 0.5208 1
Schistosoma mansoni cyclin l 0.0085 0.0506 0.0506
Trichomonas vaginalis CMGC family protein kinase 0.0098 0.0633 0.112
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0453 0.4269 0.4269
Trichomonas vaginalis AGC family protein kinase 0.0304 0.2747 0.5224
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0141 0.1071 1
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0069 0.0335 0.0335
Loa Loa (eye worm) hypothetical protein 0.0128 0.094 0.094
Trichomonas vaginalis AGC family protein kinase 0.0188 0.1556 0.2911
Echinococcus multilocularis cyclins 0.0354 0.3257 0.3257
Echinococcus granulosus cyclin t1 0.0085 0.0506 0.0506
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0167 0.1337 0.1337
Echinococcus granulosus tyrosine protein kinase HCK 0.0041 0.0046 0.0046
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0054 0.0179 0.0179
Echinococcus multilocularis cyclin B3 1 0.0354 0.3257 0.3257
Echinococcus granulosus raf serine:threonine protein kinase 0.0082 0.047 0.047
Echinococcus multilocularis nervana 2 0.0129 0.0953 0.0953
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0061 0.026 0.026
Echinococcus granulosus cyclins 0.0085 0.0506 0.0506
Schistosoma mansoni serine/threonine protein kinase 0.0367 0.3391 0.3391
Loa Loa (eye worm) SRC-1 0.0054 0.0179 0.0179
Entamoeba histolytica cyclin family protein 0.0354 0.3257 0.622
Echinococcus multilocularis cyclin y 0.0085 0.0506 0.0506
Loa Loa (eye worm) hypothetical protein 0.0069 0.0335 0.0335
Trypanosoma brucei cyclin 3 0.0085 0.0506 0.0496
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0149 0.1159 0.1816
Trichomonas vaginalis AGC family protein kinase 0.0304 0.2747 0.5224
Loa Loa (eye worm) hypothetical protein 0.0198 0.1654 0.1654
Echinococcus granulosus tyrosine protein kinase Src64B 0.0054 0.0179 0.0179
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0139 0.1057 0.1057
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0407 0.3795 0.7143
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0047 0.0113 0.0113
Giardia lamblia Cyclin B-like protein 0.0085 0.0506 0.0792
Plasmodium vivax protein kinase Crk2 0.0098 0.0633 0.4594
Echinococcus granulosus Immunoglobulin 0.0069 0.0335 0.0335
Echinococcus granulosus roundabout 2 0.0105 0.0704 0.0704
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0167 0.1337 0.1337
Echinococcus granulosus c-Jun N-terminal kinases 0.0494 0.4694 0.4694
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0062 0.0262 0.0262
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0065 0.0291 0.0063
Echinococcus granulosus cyclin G2 0.0085 0.0506 0.0506
Echinococcus granulosus cdk5 and abl1 enzyme substrate 1 0.0085 0.0506 0.0506
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0083 0.0476 0.0476
Trichomonas vaginalis AGC family protein kinase 0.0304 0.2747 0.5224
Onchocerca volvulus 0.0061 0.026 0.05
Leishmania major cyclin 9, putative 0.0085 0.0506 0.0496
Brugia malayi Cyclin, N-terminal domain containing protein 0.0085 0.0506 0.0506
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0494 0.4694 0.4694
Echinococcus multilocularis cyclin y 0.0085 0.0506 0.0506
Trypanosoma brucei cdc2-related kinase 3 0.0098 0.0633 0.0752
Plasmodium vivax cyclin dependent kinase binding protein, putative 0.0085 0.0506 0.3031
Giardia lamblia Kinase, CMGC CDK 0.0098 0.0633 0.104
Schistosoma mansoni protein kinase C 0.0076 0.0413 0.0413
Echinococcus granulosus cyclins 0.0354 0.3257 0.3257
Leishmania major mitotic cyclin, putative 0.0085 0.0506 0.0496
Loa Loa (eye worm) cyclin domain-containing protein 0.0085 0.0506 0.0506
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0098 0.0633 0.1552
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0098 0.0633 0.0633
Brugia malayi cyclin fold protein 1 variant b 0.0085 0.0506 0.0506
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0054 0.0179 0.0179
Leishmania major mitotic cyclin, putative 0.0085 0.0506 0.0496
Echinococcus multilocularis Diacylglycerol kinase theta 0.007 0.0346 0.0346
Trichomonas vaginalis cyclin B, putative 0.0545 0.5208 1
Echinococcus multilocularis tyrosine protein kinase Blk 0.0047 0.0113 0.0113
Loa Loa (eye worm) hypothetical protein 0.0545 0.5208 0.5208
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0141 0.1071 0.2704
Brugia malayi Ras association domain family 1 isoform A 0.007 0.0346 0.0346
Echinococcus granulosus MAP kinase activated protein kinase 2 0.02 0.168 0.168
Trichomonas vaginalis cyclin A, putative 0.0545 0.5208 1
Loa Loa (eye worm) AGC/NDR protein kinase 0.0167 0.1337 0.1337
Brugia malayi RhoGAP domain containing protein 0.0076 0.0413 0.0413
Schistosoma mansoni serine/threonine protein kinase 0.0494 0.4694 0.4694
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0179 0.1465 0.1465
Trichomonas vaginalis CMGC family protein kinase 0.0098 0.0633 0.112
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0367 0.3391 0.3391
Giardia lamblia Kinase, CMGC GSK 0.0061 0.026 0.0311
Echinococcus multilocularis protein kinase c iota type 0.0323 0.2938 0.2938
Brugia malayi diacylglycerol kinase 0.007 0.0346 0.0346
Brugia malayi phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative 0.0084 0.049 0.049
Echinococcus multilocularis protein kinase c epsilon type 0.0388 0.3603 0.3603
Brugia malayi Cyclin, N-terminal domain containing protein 0.0085 0.0506 0.0506
Echinococcus multilocularis G2:mitotic specific cyclin B3 0.0583 0.5599 0.5599
Loa Loa (eye worm) TK protein kinase 0.0041 0.0046 0.0046
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0076 0.0413 0.0413
Echinococcus granulosus serine threonine protein kinase nrc 0.0141 0.1071 0.1071
Loa Loa (eye worm) hypothetical protein 0.0069 0.0335 0.0335
Loa Loa (eye worm) phosphatidylinositol 3 0.016 0.1266 0.1266
Loa Loa (eye worm) hypothetical protein 0.0085 0.0506 0.0506
Brugia malayi RhoGAP domain containing protein 0.007 0.0346 0.0346
Loa Loa (eye worm) CYL-1 protein 0.0085 0.0506 0.0506
Onchocerca volvulus 0.0128 0.094 0.1804
Brugia malayi p70 ribosomal S6 kinase beta 0.0296 0.2659 0.2659
Echinococcus granulosus nervana 2 0.0129 0.0953 0.0953
Schistosoma mansoni atypical protein kinase C 0.0329 0.3003 0.3003
Entamoeba histolytica diacylglycerol kinase, putative 0.007 0.0346 0.0581
Schistosoma mansoni nephrin 0.0091 0.0562 0.0562
Echinococcus multilocularis cyclins 0.0354 0.3257 0.3257
Trichomonas vaginalis AGC family protein kinase 0.0304 0.2747 0.5224
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0054 0.0179 0.0179
Loa Loa (eye worm) hypothetical protein 0.029 0.2598 0.2598
Echinococcus multilocularis cyclin b3 0.0354 0.3257 0.3257
Loa Loa (eye worm) cyclin domain-containing protein 0.0085 0.0506 0.0506
Echinococcus granulosus protein kinase shaggy 0.0061 0.026 0.026
Echinococcus granulosus Rac GTPase activating protein 1 0.007 0.0346 0.0346
Brugia malayi P38 map kinase family protein 2 0.0407 0.3795 0.3795
Echinococcus multilocularis serine:threonine protein kinase 38 0.0167 0.1337 0.1337
Brugia malayi RhoGEF domain containing protein 0.007 0.0346 0.0346
Toxoplasma gondii diacylglycerol kinase, putative 0.007 0.0346 0.0356
Loa Loa (eye worm) hypothetical protein 0.0069 0.0335 0.0335
Brugia malayi hypothetical protein 0.0085 0.0506 0.0506
Echinococcus granulosus tyrosine protein kinase Src42A 0.0054 0.0179 0.0179
Loa Loa (eye worm) hypothetical protein 0.0078 0.0434 0.0434
Schistosoma mansoni tyrosine kinase 0.0054 0.0179 0.0179
Giardia lamblia Kinase, AGC PKA 0.0141 0.1071 0.1898
Entamoeba histolytica cyclin, putative 0.0354 0.3257 0.622
Echinococcus granulosus mitogen activated protein kinase 0.0065 0.0291 0.0291
Loa Loa (eye worm) hypothetical protein 0.1013 1 1
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0453 0.4269 0.4269
Echinococcus granulosus protein kinase c epsilon type 0.0388 0.3603 0.3603
Entamoeba histolytica hypothetical protein 0.0085 0.0506 0.0891
Trypanosoma brucei cyclin 9 0.0085 0.0506 0.0496
Echinococcus multilocularis cyclins 0.0354 0.3257 0.3257
Brugia malayi Cyclin, N-terminal domain containing protein 0.0085 0.0506 0.0506
Trypanosoma cruzi cyclin, putative 0.0545 0.5208 1
Trypanosoma brucei cyclin dependent kinase-binding protein, putative 0.0085 0.0506 0.0496
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0081 0.0463 0.0463
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0054 0.0179 0.0179
Loa Loa (eye worm) cyclin domain-containing protein 0.0085 0.0506 0.0506
Brugia malayi Variant SH3 domain containing protein 0.0076 0.0413 0.0413
Loa Loa (eye worm) hypothetical protein 0.0105 0.0704 0.0704
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0054 0.0179 0.0179
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0076 0.0407 0.0699
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0142 0.1088 0.1088
Trypanosoma cruzi cyclin 6, putative 0.0545 0.5208 1
Echinococcus multilocularis serine threonine protein kinase 0.0297 0.2676 0.2676
Echinococcus granulosus tyrosine protein kinase Fyn 0.0054 0.0179 0.0179
Echinococcus multilocularis cyclin G2 0.0085 0.0506 0.0506
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0076 0.0413 0.0413
Echinococcus granulosus Protein kinase C brain isozyme 0.0367 0.3391 0.3391

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 4.48 Inhibition of Homo sapiens (human) protoporphyrinogen oxidase ChEMBL. 20934343
Ki (binding) = 33.13 uM Inhibition of Homo sapiens (human) protoporphyrinogen oxidase ChEMBL. 20934343

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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