Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Steroid receptor seven-up type 2 | 0.0488 | 0.4452 | 0.4452 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0488 | 0.4452 | 0.4452 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0488 | 0.4452 | 0.4452 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0775 | 1 | 0.5 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0488 | 0.4452 | 0.4452 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0488 | 0.4452 | 0.4452 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0488 | 0.4452 | 0.4452 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0488 | 0.4452 | 0.4452 |
Brugia malayi | ecdysteroid receptor | 0.0488 | 0.4452 | 0.4452 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0488 | 0.4452 | 0.4452 |
Schistosoma mansoni | coup transcription factor | 0.0488 | 0.4452 | 0.4452 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.0775 | 1 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0775 | 1 | 0.5 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.0775 | 1 | 1 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.0775 | 1 | 0.5 |
Echinococcus granulosus | mitogen activated protein kinase | 0.0775 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0488 | 0.4452 | 0.4452 |
Schistosoma mansoni | nuclear hormone receptor | 0.0488 | 0.4452 | 0.4452 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.0775 | 1 | 0.5 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0488 | 0.4452 | 0.4452 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0488 | 0.4452 | 0.4452 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0488 | 0.4452 | 0.4452 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0488 | 0.4452 | 0.4452 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0488 | 0.4452 | 0.4452 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0488 | 0.4452 | 0.4452 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0488 | 0.4452 | 0.4452 |
Schistosoma mansoni | thyroid hormone receptor | 0.0488 | 0.4452 | 0.4452 |
Giardia lamblia | Kinase, CMGC MAPK | 0.0775 | 1 | 0.5 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0488 | 0.4452 | 0.4452 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0488 | 0.4452 | 0.4452 |
Loa Loa (eye worm) | hypothetical protein | 0.0488 | 0.4452 | 0.4452 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0488 | 0.4452 | 0.4452 |
Brugia malayi | nuclear hormone receptor | 0.0488 | 0.4452 | 0.4452 |
Loa Loa (eye worm) | hypothetical protein | 0.0488 | 0.4452 | 0.4452 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.0775 | 1 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0488 | 0.4452 | 0.4452 |
Trypanosoma brucei | protein kinase, putative | 0.0775 | 1 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0488 | 0.4452 | 0.4452 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0775 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0488 | 0.4452 | 0.4452 |
Schistosoma mansoni | thyroid hormone receptor | 0.0488 | 0.4452 | 0.4452 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0775 | 1 | 0.5 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0488 | 0.4452 | 0.4452 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0488 | 0.4452 | 0.4452 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0488 | 0.4452 | 0.4452 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0488 | 0.4452 | 0.4452 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0488 | 0.4452 | 0.4452 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0488 | 0.4452 | 0.4452 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0488 | 0.4452 | 0.4452 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0775 | 1 | 0.5 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.0775 | 1 | 1 |
Echinococcus granulosus | FTZ F1 alpha | 0.0488 | 0.4452 | 0.4452 |
Loa Loa (eye worm) | hypothetical protein | 0.0488 | 0.4452 | 0.4452 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.0775 | 1 | 0.5 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0488 | 0.4452 | 0.4452 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0488 | 0.4452 | 0.4452 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.0775 | 1 | 1 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0488 | 0.4452 | 0.4452 |
Loa Loa (eye worm) | hypothetical protein | 0.0488 | 0.4452 | 0.4452 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0488 | 0.4452 | 0.4452 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0488 | 0.4452 | 0.4452 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0488 | 0.4452 | 0.4452 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0775 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0488 | 0.4452 | 0.4452 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0488 | 0.4452 | 0.4452 |
Loa Loa (eye worm) | hypothetical protein | 0.0488 | 0.4452 | 0.4452 |
Loa Loa (eye worm) | hypothetical protein | 0.0488 | 0.4452 | 0.4452 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0488 | 0.4452 | 0.4452 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0488 | 0.4452 | 0.5 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0488 | 0.4452 | 0.4452 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0488 | 0.4452 | 0.4452 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0775 | 1 | 0.5 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0488 | 0.4452 | 0.4452 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.0775 | 1 | 0.5 |
Brugia malayi | nuclear receptor NHR-88 | 0.0488 | 0.4452 | 0.4452 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0488 | 0.4452 | 0.4452 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0488 | 0.4452 | 0.4452 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0488 | 0.4452 | 0.5 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0488 | 0.4452 | 0.4452 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0488 | 0.4452 | 0.4452 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0488 | 0.4452 | 0.4452 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.0775 | 1 | 0.5 |
Brugia malayi | steroid hormone receptor | 0.0488 | 0.4452 | 0.4452 |
Onchocerca volvulus | 0.0488 | 0.4452 | 0.5 | |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0488 | 0.4452 | 0.4452 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0488 | 0.4452 | 0.4452 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0488 | 0.4452 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0488 | 0.4452 | 0.4452 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0488 | 0.4452 | 0.4452 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0488 | 0.4452 | 0.4452 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0488 | 0.4452 | 0.4452 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.