Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | Neurotrimin precursor (hNT) | 0.0077 | 0.1578 | 0.1472 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0077 | 0.1578 | 0.1472 |
Echinococcus multilocularis | neuropeptide receptor | 0.0046 | 0.0229 | 0.0105 |
Entamoeba histolytica | purine nucleoside phosphorylase, putative | 0.0057 | 0.069 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.1578 | 0.1838 |
Echinococcus multilocularis | neuropeptide receptor | 0.0046 | 0.0229 | 0.0105 |
Mycobacterium tuberculosis | Probable purine nucleoside phosphorylase DeoD (inosine phosphorylase) (PNP) | 0.0273 | 1 | 1 |
Treponema pallidum | purine nucleoside phosphorylase (deoD) | 0.0057 | 0.069 | 0.5 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.009 | 0.2137 | 0.2037 |
Brugia malayi | neuropeptide F receptor | 0.0046 | 0.0229 | 0.0105 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0148 | 0.4604 | 0.4536 |
Mycobacterium ulcerans | bifunctional Mta/Sah nucleosidase Mtn | 0.0057 | 0.069 | 0.0506 |
Schistosoma mansoni | titin | 0.0073 | 0.1393 | 0.1284 |
Schistosoma mansoni | methylthioadenosine phosphorylase | 0.0057 | 0.069 | 0.0572 |
Brugia malayi | Serotonin receptor | 0.0046 | 0.0229 | 0.0105 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.0046 | 0.0229 | 0.0105 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0046 | 0.0229 | 0.0105 |
Brugia malayi | hypothetical protein | 0.0046 | 0.0229 | 0.0105 |
Trypanosoma brucei | methylthioadenosine phosphorylase, putative | 0.0057 | 0.069 | 0.2851 |
Onchocerca volvulus | 0.0073 | 0.1393 | 0.1192 | |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0046 | 0.0229 | 0.0105 |
Echinococcus granulosus | neuropeptide receptor | 0.0046 | 0.0229 | 0.0105 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.0046 | 0.0229 | 0.0105 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0046 | 0.0229 | 0.0105 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0046 | 0.0229 | 0.0105 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0046 | 0.0229 | 0.0105 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0046 | 0.0229 | 0.0105 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0046 | 0.0229 | 0.0105 |
Schistosoma mansoni | methylthioadenosine phosphorylase | 0.0057 | 0.069 | 0.0572 |
Echinococcus granulosus | g protein coupled receptor | 0.0046 | 0.0229 | 0.0105 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0152 | 0.4789 | 0.4723 |
Leishmania major | methylthioadenosine phosphorylase, putative | 0.0057 | 0.069 | 0.2851 |
Echinococcus granulosus | roundabout 2 | 0.0077 | 0.1578 | 0.1472 |
Schistosoma mansoni | histamine h1 receptor | 0.0046 | 0.0229 | 0.0105 |
Echinococcus granulosus | orexin receptor type 2 | 0.0046 | 0.0229 | 0.0105 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0046 | 0.0229 | 0.0105 |
Brugia malayi | ORL1-like opioid receptor | 0.0046 | 0.0229 | 0.0105 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0046 | 0.0229 | 0.0105 |
Schistosoma mansoni | low-density lipoprotein receptor (ldl) | 0.0073 | 0.1393 | 0.1284 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0046 | 0.0229 | 0.0105 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0046 | 0.0229 | 0.0105 |
Toxoplasma gondii | acetyl-coA carboxylase ACC2 | 0.0086 | 0.1935 | 1 |
Leishmania major | acetyl-CoA carboxylase, putative | 0.0086 | 0.1935 | 1 |
Schistosoma mansoni | methylcrotonyl-CoA carboxylase | 0.0045 | 0.0194 | 0.007 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.009 | 0.2137 | 0.2037 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0046 | 0.0229 | 0.0105 |
Echinococcus granulosus | inosine guanosine and xanthosine phosphorylase | 0.0217 | 0.7569 | 0.7538 |
Onchocerca volvulus | Basement membrane proteoglycan homolog | 0.0073 | 0.1393 | 0.1192 |
Echinococcus multilocularis | g protein coupled receptor | 0.0046 | 0.0229 | 0.0105 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0046 | 0.0229 | 0.0105 |
Echinococcus multilocularis | purine nucleoside phosphorylase | 0.0273 | 1 | 1 |
Brugia malayi | putative neuropeptide receptor | 0.0046 | 0.0229 | 0.0105 |
Brugia malayi | hypothetical protein | 0.0046 | 0.0229 | 0.0105 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.0046 | 0.0229 | 0.0105 |
Trypanosoma cruzi | nucleoside phosphorylase, putative | 0.0057 | 0.069 | 1 |
Toxoplasma gondii | Purine nucleoside phosphorylase | 0.0057 | 0.069 | 0.2851 |
Treponema pallidum | uridine phosphorylase (udp) | 0.0057 | 0.069 | 0.5 |
Schistosoma mansoni | cell adhesion molecule | 0.0077 | 0.1578 | 0.1472 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0046 | 0.0229 | 0.0105 |
Echinococcus multilocularis | acetyl coenzyme A carboxylase 1 | 0.0086 | 0.1935 | 0.1833 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0046 | 0.0229 | 0.0105 |
Brugia malayi | G protein-coupled receptor | 0.0046 | 0.0229 | 0.0105 |
Echinococcus multilocularis | conserved hypothetical protein | 0.009 | 0.2137 | 0.2037 |
Schistosoma mansoni | biogenic amine receptor | 0.0046 | 0.0229 | 0.0105 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0152 | 0.4789 | 0.4723 |
Mycobacterium tuberculosis | Hypothetical protein | 0.0057 | 0.069 | 0.0506 |
Schistosoma mansoni | amine GPCR | 0.0046 | 0.0229 | 0.0105 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0046 | 0.0229 | 0.0105 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0057 | 0.069 | 0.0506 |
Schistosoma mansoni | opsin-like receptor | 0.0046 | 0.0229 | 0.0105 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0046 | 0.0229 | 0.0105 |
Echinococcus multilocularis | purine nucleoside phosphorylase | 0.0217 | 0.7569 | 0.7538 |
Schistosoma mansoni | amine GPCR | 0.0046 | 0.0229 | 0.0105 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0046 | 0.0229 | 0.0105 |
Echinococcus multilocularis | allatostatin A receptor | 0.0046 | 0.0229 | 0.0105 |
Schistosoma mansoni | neuropeptide receptor | 0.0046 | 0.0229 | 0.0105 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.0046 | 0.0229 | 0.0105 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0046 | 0.0229 | 0.0105 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0046 | 0.0229 | 0.0105 |
Schistosoma mansoni | hypothetical protein | 0.0073 | 0.1393 | 0.1284 |
Brugia malayi | Carboxyl transferase domain containing protein | 0.0081 | 0.1757 | 0.1653 |
Echinococcus multilocularis | low density lipoprotein receptor (ldl) | 0.0073 | 0.1393 | 0.1284 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0046 | 0.0229 | 0.0105 |
Brugia malayi | Dopamine receptor protein 2 | 0.0046 | 0.0229 | 0.0105 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.0046 | 0.0229 | 0.0105 |
Echinococcus multilocularis | purine nucleoside phosphorylase | 0.0217 | 0.7569 | 0.7538 |
Mycobacterium ulcerans | 5'-methylthioadenosine phosphorylase | 0.0057 | 0.069 | 0.0506 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0046 | 0.0229 | 0.0105 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.0046 | 0.0229 | 0.0105 |
Echinococcus granulosus | low density lipoprotein receptor ldl | 0.0073 | 0.1393 | 0.1284 |
Schistosoma mansoni | hypothetical protein | 0.009 | 0.2137 | 0.2037 |
Trypanosoma cruzi | 3-methylcrotonyl-CoA carboxylase, putative | 0.0045 | 0.0194 | 0.2807 |
Echinococcus granulosus | purine nucleoside phosphorylase | 0.0273 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0046 | 0.0229 | 0.0105 |
Brugia malayi | neuropeptide F receptor | 0.0046 | 0.0229 | 0.0105 |
Mycobacterium leprae | probable uridine phosphorylase | 0.0057 | 0.069 | 0.0506 |
Echinococcus multilocularis | g protein coupled receptor | 0.0046 | 0.0229 | 0.0105 |
Echinococcus multilocularis | basement membrane specific heparan sulfate | 0.0077 | 0.1578 | 0.1472 |
Leishmania major | nucleoside phosphorylase-like protein | 0.0057 | 0.069 | 0.2851 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0046 | 0.0229 | 0.0105 |
Treponema pallidum | pfs protein (pfs) | 0.0057 | 0.069 | 0.5 |
Echinococcus granulosus | fmrfamide receptor | 0.0046 | 0.0229 | 0.0105 |
Chlamydia trachomatis | AMP nucleosidase | 0.0057 | 0.069 | 1 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0046 | 0.0229 | 0.0105 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0046 | 0.0229 | 0.0105 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0046 | 0.0229 | 0.0105 |
Echinococcus multilocularis | g-protein coupled receptor | 0.0046 | 0.0229 | 0.0105 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0046 | 0.0229 | 0.0105 |
Brugia malayi | Serotonin receptor | 0.0046 | 0.0229 | 0.0105 |
Echinococcus granulosus | sex peptide receptor | 0.0046 | 0.0229 | 0.0105 |
Schistosoma mansoni | neuropeptide receptor | 0.0046 | 0.0229 | 0.0105 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0046 | 0.0229 | 0.0105 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0046 | 0.0229 | 0.0105 |
Onchocerca volvulus | Netrin receptor homolog | 0.0073 | 0.1393 | 0.1192 |
Brugia malayi | larval opioid receptor | 0.0046 | 0.0229 | 0.0105 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0046 | 0.0229 | 0.0105 |
Trypanosoma cruzi | methylthioadenosine phosphorylase, putative | 0.0057 | 0.069 | 1 |
Entamoeba histolytica | purine nucleoside phosphorylase, putative | 0.0057 | 0.069 | 1 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.0046 | 0.0229 | 0.0105 |
Giardia lamblia | Purine nucleoside phosphorylase lateral transfer candidate | 0.0273 | 1 | 1 |
Echinococcus multilocularis | purine nucleoside phosphorylase | 0.0273 | 1 | 1 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0046 | 0.0229 | 0.0105 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0046 | 0.0229 | 0.0105 |
Echinococcus multilocularis | somatostatin receptor | 0.0046 | 0.0229 | 0.0105 |
Brugia malayi | sulfakinin receptor protein | 0.0046 | 0.0229 | 0.0105 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0046 | 0.0229 | 0.0105 |
Brugia malayi | follicle stimulating hormone receptor | 0.0046 | 0.0229 | 0.0105 |
Echinococcus multilocularis | roundabout 2 | 0.0077 | 0.1578 | 0.1472 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0046 | 0.0229 | 0.0105 |
Brugia malayi | G-protein coupled receptor | 0.0046 | 0.0229 | 0.0105 |
Loa Loa (eye worm) | carboxyl transferase domain-containing protein | 0.0081 | 0.1757 | 0.2082 |
Schistosoma mansoni | amine GPCR | 0.0046 | 0.0229 | 0.0105 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0046 | 0.0229 | 0.0105 |
Echinococcus granulosus | purine nucleoside phosphorylase | 0.0273 | 1 | 1 |
Loa Loa (eye worm) | TK/KIN16 protein kinase | 0.0077 | 0.1578 | 0.1838 |
Plasmodium falciparum | biotin carboxylase subunit of acetyl CoA carboxylase, putative | 0.0086 | 0.1935 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.1578 | 0.1838 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0046 | 0.0229 | 0.0105 |
Schistosoma mansoni | hypothetical protein | 0.0046 | 0.0229 | 0.0105 |
Echinococcus multilocularis | orexin receptor type 2 | 0.0046 | 0.0229 | 0.0105 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0046 | 0.0229 | 0.0105 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0181 | 0.602 | 0.597 |
Entamoeba histolytica | MTA/SAH nucleosidase, putative | 0.0057 | 0.069 | 1 |
Schistosoma mansoni | uridine phosphorylase | 0.0057 | 0.069 | 0.0572 |
Onchocerca volvulus | Tyrosine kinase homolog | 0.0073 | 0.1393 | 0.1192 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.0046 | 0.0229 | 0.0105 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0046 | 0.0229 | 0.0105 |
Brugia malayi | Dopamine receptor | 0.0046 | 0.0229 | 0.0105 |
Schistosoma mansoni | myosin xvIII | 0.0046 | 0.0229 | 0.0105 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0046 | 0.0229 | 0.0105 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0046 | 0.0229 | 0.0105 |
Echinococcus multilocularis | irregular chiasm roughest protein immunoglobulin set domain containing protein | 0.009 | 0.2137 | 0.2037 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0046 | 0.0229 | 0.0105 |
Echinococcus granulosus | neuropeptide receptor | 0.0046 | 0.0229 | 0.0105 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0133 | 0.3953 | 0.3877 |
Echinococcus granulosus | g protein coupled receptor | 0.0046 | 0.0229 | 0.0105 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0046 | 0.0229 | 0.0105 |
Echinococcus granulosus | acetyl coenzyme A carboxylase 1 | 0.0086 | 0.1935 | 0.1833 |
Schistosoma mansoni | hypothetical protein | 0.0046 | 0.0229 | 0.0105 |
Plasmodium vivax | biotin carboxylase subunit of acetyl CoA carboxylase, putative | 0.0086 | 0.1935 | 1 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0046 | 0.0229 | 0.0105 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0046 | 0.0229 | 0.0105 |
Schistosoma mansoni | uridine phosphorylase | 0.0057 | 0.069 | 0.0572 |
Brugia malayi | hypothetical protein | 0.0046 | 0.0229 | 0.0105 |
Trypanosoma cruzi | nucleoside phosphorylase, putative | 0.0057 | 0.069 | 1 |
Mycobacterium tuberculosis | Probable bifunctional MTA/SAH nucleosidase Mtn: 5'-methylthioadenosine nucleosidase (methylthioadenosine methylthioribohydrolase | 0.0057 | 0.069 | 0.0506 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.0046 | 0.0229 | 0.0105 |
Schistosoma mansoni | hypothetical protein | 0.0152 | 0.4789 | 0.4723 |
Trypanosoma brucei | acetyl-CoA carboxylase | 0.0086 | 0.1935 | 1 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0046 | 0.0229 | 0.0105 |
Echinococcus granulosus | purine nucleoside phosphorylase | 0.0273 | 1 | 1 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0046 | 0.0229 | 0.0105 |
Echinococcus multilocularis | serotonin receptor | 0.0046 | 0.0229 | 0.0105 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0046 | 0.0229 | 0.0105 |
Mycobacterium leprae | Probable purine nucleoside phosphorylase DeoD (INOSINE PHOSPHORYLASE) (PNP) | 0.0273 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0077 | 0.1578 | 0.1472 |
Brugia malayi | hypothetical protein | 0.0046 | 0.0229 | 0.0105 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.0046 | 0.0229 | 0.0105 |
Onchocerca volvulus | 0.0073 | 0.1393 | 0.1192 | |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0046 | 0.0229 | 0.0105 |
Echinococcus granulosus | hemicentin 1 | 0.0073 | 0.1393 | 0.1284 |
Echinococcus granulosus | allatostatin A receptor | 0.0046 | 0.0229 | 0.0105 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0046 | 0.0229 | 0.0105 |
Echinococcus granulosus | uridine phosphorylase 1 | 0.0057 | 0.069 | 0.0572 |
Onchocerca volvulus | 0.0073 | 0.1393 | 0.1192 | |
Echinococcus granulosus | neuroglian | 0.0077 | 0.1578 | 0.1472 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0046 | 0.0229 | 0.0105 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0046 | 0.0229 | 0.0105 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0046 | 0.0229 | 0.0105 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0148 | 0.4604 | 0.4536 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0046 | 0.0229 | 0.0105 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.0046 | 0.0229 | 0.0105 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.0046 | 0.0229 | 0.0105 |
Brugia malayi | uridine phosphorylase family protein | 0.0057 | 0.069 | 0.0572 |
Echinococcus multilocularis | purine nucleoside phosphorylase | 0.0273 | 1 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0046 | 0.0229 | 0.0105 |
Toxoplasma gondii | acetyl-CoA carboxylase ACC1 | 0.0086 | 0.1935 | 1 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0046 | 0.0229 | 0.0105 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.0046 | 0.0229 | 0.0105 |
Toxoplasma gondii | phosphorylase family protein | 0.0057 | 0.069 | 0.2851 |
Entamoeba histolytica | purine nucleoside phosphorylase, putative | 0.0057 | 0.069 | 1 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0046 | 0.0229 | 0.0105 |
Schistosoma mansoni | methylthioadenosine phosphorylase | 0.0057 | 0.069 | 0.0572 |
Brugia malayi | hypothetical protein | 0.0046 | 0.0229 | 0.0105 |
Schistosoma mansoni | methylcrotonyl-CoA carboxylase | 0.0045 | 0.0194 | 0.007 |
Schistosoma mansoni | defective proboscis extension response (dpr)-related | 0.0077 | 0.1578 | 0.1472 |
Echinococcus granulosus | neuropeptide s receptor | 0.0046 | 0.0229 | 0.0105 |
Schistosoma mansoni | hypothetical protein | 0.009 | 0.2137 | 0.2037 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0046 | 0.0229 | 0.0105 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0046 | 0.0229 | 0.0105 |
Brugia malayi | MTAP | 0.0057 | 0.069 | 0.0572 |
Loa Loa (eye worm) | hypothetical protein | 0.015 | 0.4713 | 0.6109 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0046 | 0.0229 | 0.0105 |
Echinococcus granulosus | propionyl coenzyme A carboxylase alpha chain | 0.0045 | 0.0194 | 0.007 |
Entamoeba histolytica | purine nucleoside phosphorylase, putative | 0.0057 | 0.069 | 1 |
Brugia malayi | AKH receptor | 0.0046 | 0.0229 | 0.0105 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.0046 | 0.0229 | 0.0105 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0046 | 0.0229 | 0.0105 |
Echinococcus multilocularis | methylthioadenosine phosphorylase | 0.0057 | 0.069 | 0.0572 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0046 | 0.0229 | 0.0105 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0046 | 0.0229 | 0.0105 |
Echinococcus granulosus | g-protein coupled receptor | 0.0046 | 0.0229 | 0.0105 |
Toxoplasma gondii | phosphorylase family protein | 0.0057 | 0.069 | 0.2851 |
Brugia malayi | hypothetical protein | 0.0163 | 0.5271 | 0.5211 |
Echinococcus multilocularis | g protein coupled receptor | 0.0046 | 0.0229 | 0.0105 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0046 | 0.0229 | 0.0105 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0046 | 0.0229 | 0.0105 |
Loa Loa (eye worm) | uridine phosphorylase | 0.0057 | 0.069 | 0.0628 |
Trypanosoma cruzi | 3-methylcrotonyl-CoA carboxylase, putative | 0.0045 | 0.0194 | 0.2807 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0077 | 0.1578 | 0.1472 |
Echinococcus granulosus | defective proboscis extension response | 0.0077 | 0.1578 | 0.1472 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0046 | 0.0229 | 0.0105 |
Echinococcus multilocularis | hemicentin 1 | 0.0073 | 0.1393 | 0.1284 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0046 | 0.0229 | 0.0105 |
Schistosoma mansoni | opsin-like receptor | 0.0046 | 0.0229 | 0.0105 |
Echinococcus multilocularis | serotonin receptor | 0.0046 | 0.0229 | 0.0105 |
Echinococcus multilocularis | purine nucleoside phosphorylase | 0.0273 | 1 | 1 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0046 | 0.0229 | 0.0105 |
Echinococcus granulosus | nephrin | 0.009 | 0.2137 | 0.2037 |
Schistosoma mansoni | opsin-like receptor | 0.0046 | 0.0229 | 0.0105 |
Entamoeba histolytica | hypothetical protein | 0.0057 | 0.069 | 1 |
Schistosoma mansoni | neuropeptide receptor | 0.0046 | 0.0229 | 0.0105 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.1578 | 0.1838 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0046 | 0.0229 | 0.0105 |
Schistosoma mansoni | hypothetical protein | 0.0046 | 0.0229 | 0.0105 |
Echinococcus granulosus | neurotracting:lsamp:neurotrimin:obcam | 0.0077 | 0.1578 | 0.1472 |
Onchocerca volvulus | 0.0073 | 0.1393 | 0.1192 | |
Echinococcus granulosus | g protein coupled receptor | 0.0046 | 0.0229 | 0.0105 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.009 | 0.2137 | 0.2599 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0046 | 0.0229 | 0.0105 |
Brugia malayi | G-protein coupled receptor | 0.0046 | 0.0229 | 0.0105 |
Echinococcus granulosus | serotonin receptor | 0.0046 | 0.0229 | 0.0105 |
Echinococcus granulosus | irregular chiasm roughest protein | 0.009 | 0.2137 | 0.2037 |
Echinococcus granulosus | purine nucleoside phosphorylase | 0.0273 | 1 | 1 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0046 | 0.0229 | 0.0105 |
Schistosoma mansoni | hypothetical protein | 0.0046 | 0.0229 | 0.0105 |
Schistosoma mansoni | nephrin | 0.0077 | 0.1578 | 0.1472 |
Echinococcus multilocularis | Immunoglobulin | 0.0168 | 0.5456 | 0.5399 |
Echinococcus multilocularis | uridine phosphorylase 1 | 0.0057 | 0.069 | 0.0572 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.0046 | 0.0229 | 0.0105 |
Loa Loa (eye worm) | hypothetical protein | 0.0217 | 0.7569 | 1 |
Echinococcus granulosus | twitchin | 0.0077 | 0.1578 | 0.1472 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0046 | 0.0229 | 0.0105 |
Trypanosoma cruzi | methylthioadenosine phosphorylase, putative | 0.0057 | 0.069 | 1 |
Brugia malayi | Dopamine receptor protein 1 | 0.0046 | 0.0229 | 0.0105 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0046 | 0.0229 | 0.0105 |
Trypanosoma cruzi | nucleoside phosphorylase, putative | 0.0057 | 0.069 | 1 |
Brugia malayi | hypothetical protein | 0.0046 | 0.0229 | 0.0105 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.1578 | 0.1838 |
Echinococcus multilocularis | fmrfamide receptor | 0.0046 | 0.0229 | 0.0105 |
Echinococcus multilocularis | propionyl coenzyme A carboxylase alpha chain | 0.0045 | 0.0194 | 0.007 |
Entamoeba histolytica | purine nucleoside phosphorylase, putative | 0.0057 | 0.069 | 1 |
Echinococcus granulosus | purine nucleoside phosphorylase | 0.0273 | 1 | 1 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0046 | 0.0229 | 0.0105 |
Schistosoma mansoni | purine nucleoside phosphorylase | 0.0273 | 1 | 1 |
Echinococcus multilocularis | purine nucleoside phosphorylase | 0.0273 | 1 | 1 |
Schistosoma mansoni | pyruvate carboxylase | 0.0045 | 0.0194 | 0.007 |
Echinococcus multilocularis | fmrfamide receptor | 0.0046 | 0.0229 | 0.0105 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.0046 | 0.0229 | 0.0105 |
Onchocerca volvulus | Putative titin | 0.0073 | 0.1393 | 0.1192 |
Brugia malayi | GnHR receptor homolog | 0.0046 | 0.0229 | 0.0105 |
Brugia malayi | Fibronectin type III domain containing protein | 0.0077 | 0.1578 | 0.1472 |
Echinococcus granulosus | contactin | 0.0073 | 0.1393 | 0.1284 |
Echinococcus multilocularis | neuroglian | 0.0077 | 0.1578 | 0.1472 |
Brugia malayi | hypothetical protein | 0.0046 | 0.0229 | 0.0105 |
Mycobacterium ulcerans | purine nucleoside phosphorylase | 0.0273 | 1 | 1 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0046 | 0.0229 | 0.0105 |
Brugia malayi | hypothetical protein | 0.0046 | 0.0229 | 0.0105 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.0046 | 0.0229 | 0.0105 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.0046 | 0.0229 | 0.0105 |
Schistosoma mansoni | thyroid hormone receptor | 0.0181 | 0.602 | 0.597 |
Trypanosoma brucei | uridine phosphorylase | 0.0057 | 0.069 | 0.2851 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.009 | 0.2137 | 0.2599 |
Brugia malayi | hypothetical protein | 0.0046 | 0.0229 | 0.0105 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.1578 | 0.1838 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.1578 | 0.1838 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.0046 | 0.0229 | 0.0105 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0046 | 0.0229 | 0.0105 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.1578 | 0.1838 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0046 | 0.0229 | 0.0105 |
Schistosoma mansoni | neuropeptide receptor | 0.0046 | 0.0229 | 0.0105 |
Brugia malayi | Melatonin receptor type 1A | 0.0046 | 0.0229 | 0.0105 |
Echinococcus granulosus | Immunoglobulin | 0.009 | 0.2137 | 0.2037 |
Schistosoma mansoni | adenoreceptor | 0.0046 | 0.0229 | 0.0105 |
Schistosoma mansoni | vesicular amine transporter | 0.0077 | 0.1578 | 0.1472 |
Echinococcus granulosus | nephrin | 0.009 | 0.2137 | 0.2037 |
Echinococcus multilocularis | sex peptide receptor | 0.0046 | 0.0229 | 0.0105 |
Echinococcus granulosus | hypothetical protein | 0.0046 | 0.0229 | 0.0105 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0046 | 0.0229 | 0.0105 |
Schistosoma mansoni | amine GPCR | 0.0046 | 0.0229 | 0.0105 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0046 | 0.0229 | 0.0105 |
Onchocerca volvulus | Purine nucleoside phosphorylase homolog | 0.0273 | 1 | 1 |
Schistosoma mansoni | amine GPCR | 0.0046 | 0.0229 | 0.0105 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0046 | 0.0229 | 0.0105 |
Schistosoma mansoni | biogenic amine receptor | 0.0046 | 0.0229 | 0.0105 |
Echinococcus granulosus | somatostatin receptor | 0.0046 | 0.0229 | 0.0105 |
Trichomonas vaginalis | purine nucleoside phosphorylase I, putative | 0.0273 | 1 | 1 |
Echinococcus granulosus | methylthioadenosine phosphorylase | 0.0057 | 0.069 | 0.0572 |
Schistosoma mansoni | acetyl-CoA carboxylase | 0.0086 | 0.1935 | 0.1833 |
Echinococcus multilocularis | nephrin | 0.009 | 0.2137 | 0.2037 |
Wolbachia endosymbiont of Brugia malayi | Acetyl/propionyl-CoA carboxylase, alpha subunit | 0.0045 | 0.0194 | 0.5 |
Schistosoma mansoni | biogenic amine receptor | 0.0046 | 0.0229 | 0.0105 |
Echinococcus multilocularis | Immunoglobulin | 0.0077 | 0.1578 | 0.1472 |
Loa Loa (eye worm) | S-methyl-5'-thioadenosine phosphorylase MTAP | 0.0057 | 0.069 | 0.0628 |
Echinococcus granulosus | purine nucleoside phosphorylase | 0.0273 | 1 | 1 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0046 | 0.0229 | 0.0105 |
Echinococcus granulosus | purine nucleoside phosphorylase | 0.0273 | 1 | 1 |
Schistosoma mansoni | purine nucleoside phosphorylase | 0.0273 | 1 | 1 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.0046 | 0.0229 | 0.0105 |
Echinococcus multilocularis | purine nucleoside phosphorylase | 0.0273 | 1 | 1 |
Echinococcus granulosus | purine nucleoside phosphorylase | 0.0273 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.1578 | 0.1838 |
Schistosoma mansoni | thyroid hormone receptor | 0.0181 | 0.602 | 0.597 |
Echinococcus granulosus | Immunoglobulin | 0.0077 | 0.1578 | 0.1472 |
Brugia malayi | RE15519p | 0.0046 | 0.0229 | 0.0105 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Potency (functional) | 27.306 uM | PubChem BioAssay: Tox21. qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 38.8952 uM | PubChem BioAssay: Tox21. qHTS assay to identify small molecule agonists of the androgen receptor (AR) signaling pathway. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 54.941 uM | PubChem BioAssay: Tox21. qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 54.941 uM | PubChem BioAssay: Tox21. qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway. (Class of assay: confirmatory) | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.