Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium vivax | serine-repeat antigen 4 (SERA), putative | 0.0133 | 0.0941 | 0.1759 |
Loa Loa (eye worm) | hypothetical protein | 0.0175 | 0.134 | 0.134 |
Loa Loa (eye worm) | cysteine proteinase cathepsin Z | 0.0133 | 0.0941 | 0.0941 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0133 | 0.0941 | 0.1759 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.1077 | 1 | 1 |
Loa Loa (eye worm) | cysteine protease | 0.0593 | 0.5351 | 0.5351 |
Leishmania major | cathepsin L-like protease | 0.0593 | 0.5351 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0133 | 0.0941 | 0.0941 |
Brugia malayi | cathepsin Z-like cysteine proteinase | 0.0133 | 0.0941 | 0.0941 |
Loa Loa (eye worm) | hypothetical protein | 0.0186 | 0.1451 | 0.1451 |
Onchocerca volvulus | 0.0175 | 0.134 | 0.2504 | |
Giardia lamblia | Dipeptidyl-peptidase I precursor | 0.0133 | 0.0941 | 0.2515 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin H-like cysteine peptidase | 0.0133 | 0.0941 | 0.1759 |
Brugia malayi | hypothetical protein | 0.0233 | 0.1896 | 0.1896 |
Plasmodium falciparum | serine repeat antigen 4 | 0.0133 | 0.0941 | 0.1759 |
Mycobacterium tuberculosis | Probable pyruvate kinase PykA | 0.0035 | 0 | 0.5 |
Plasmodium vivax | serine-repeat antigen (SERA) | 0.0133 | 0.0941 | 0.1759 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0593 | 0.5351 | 1 |
Onchocerca volvulus | 0.0593 | 0.5351 | 1 | |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0406 | 0.3563 | 0.3563 |
Toxoplasma gondii | cathepsin CPC2 | 0.0133 | 0.0941 | 0.1759 |
Giardia lamblia | Dipeptidyl-peptidase I precursor | 0.0133 | 0.0941 | 0.2515 |
Plasmodium falciparum | serine repeat antigen 8 | 0.0133 | 0.0941 | 0.1759 |
Loa Loa (eye worm) | hypothetical protein | 0.0133 | 0.0941 | 0.0941 |
Trypanosoma cruzi | cysteine protease, putative | 0.0319 | 0.2729 | 0.2729 |
Plasmodium vivax | dipeptidyl aminopeptidase 2, putative | 0.0133 | 0.0941 | 0.1759 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0133 | 0.0941 | 0.1759 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0425 | 0.3743 | 0.3743 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0133 | 0.0941 | 0.1759 |
Schistosoma mansoni | subfamily C1A non-peptidase homologue (C01 family) | 0.0133 | 0.0941 | 0.0941 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1077 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0593 | 0.5351 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0593 | 0.5351 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0133 | 0.0941 | 0.1759 |
Plasmodium vivax | vivapain-2 | 0.0593 | 0.5351 | 1 |
Echinococcus granulosus | cathepsin L cysteine protease | 0.0319 | 0.2729 | 0.2729 |
Entamoeba histolytica | cysteine protease, putative | 0.0319 | 0.2729 | 0.4054 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0425 | 0.3743 | 0.3743 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0319 | 0.2729 | 0.2729 |
Giardia lamblia | Cathepsin B precursor | 0.0133 | 0.0941 | 0.2515 |
Entamoeba histolytica | cysteine protease, putative | 0.0319 | 0.2729 | 0.4054 |
Entamoeba histolytica | rodhanase-like domain containing protein | 0.0175 | 0.134 | 0.0904 |
Schistosoma mansoni | tar DNA-binding protein | 0.0061 | 0.0253 | 0.0253 |
Echinococcus multilocularis | cathepsin L | 0.0133 | 0.0941 | 0.0941 |
Giardia lamblia | Cathepsin B precursor | 0.0133 | 0.0941 | 0.2515 |
Entamoeba histolytica | cysteine protease, putative | 0.0319 | 0.2729 | 0.4054 |
Echinococcus granulosus | cathepsin l1 | 0.0406 | 0.3563 | 0.3563 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0133 | 0.0941 | 0.1759 |
Onchocerca volvulus | 0.0593 | 0.5351 | 1 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0593 | 0.5351 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0593 | 0.5351 | 1 |
Trichomonas vaginalis | mitotic inducer phosphatase CDC25, putative | 0.0175 | 0.134 | 0.2504 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0593 | 0.5351 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0593 | 0.5351 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0133 | 0.0941 | 0.0941 |
Onchocerca volvulus | 0.0175 | 0.134 | 0.2504 | |
Brugia malayi | Cathepsin L-like precursor | 0.0593 | 0.5351 | 0.5351 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0593 | 0.5351 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0133 | 0.0941 | 0.2515 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0319 | 0.2729 | 0.51 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0593 | 0.5351 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0319 | 0.2729 | 0.4054 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0593 | 0.5351 | 0.5351 |
Loa Loa (eye worm) | hypothetical protein | 0.0161 | 0.1209 | 0.1209 |
Leishmania major | cathepsin L-like protease | 0.0593 | 0.5351 | 1 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0593 | 0.5351 | 0.5351 |
Schistosoma mansoni | tar DNA-binding protein | 0.0061 | 0.0253 | 0.0253 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0593 | 0.5351 | 0.5351 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0133 | 0.0941 | 0.0941 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0133 | 0.0941 | 0.0941 |
Plasmodium falciparum | serine repeat antigen 5 | 0.0133 | 0.0941 | 0.1759 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0133 | 0.0941 | 0.0941 |
Schistosoma mansoni | hypothetical protein | 0.0178 | 0.1374 | 0.1374 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0133 | 0.0941 | 0.1759 |
Echinococcus multilocularis | geminin | 0.0178 | 0.1374 | 0.1374 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0593 | 0.5351 | 0.5351 |
Entamoeba histolytica | cysteine protease, putative | 0.0319 | 0.2729 | 0.4054 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0593 | 0.5351 | 1 |
Plasmodium falciparum | serine repeat antigen 9 | 0.0133 | 0.0941 | 0.1759 |
Giardia lamblia | Cysteine protease | 0.0133 | 0.0941 | 0.2515 |
Schistosoma mansoni | cathepsin s | 0.0186 | 0.1451 | 0.1451 |
Giardia lamblia | Cathepsin B-like cysteine proteinase 3 precursor | 0.0133 | 0.0941 | 0.2515 |
Schistosoma mansoni | subfamily C1A unassigned peptidase (C01 family) | 0.0133 | 0.0941 | 0.0941 |
Plasmodium vivax | serine-repeat antigen 4 (SERA) | 0.0133 | 0.0941 | 0.1759 |
Onchocerca volvulus | 0.0175 | 0.134 | 0.2504 | |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0319 | 0.2729 | 0.2729 |
Entamoeba histolytica | cysteine protease, putative | 0.0319 | 0.2729 | 0.4054 |
Echinococcus granulosus | cathepsin L | 0.0133 | 0.0941 | 0.0941 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0593 | 0.5351 | 1 |
Echinococcus granulosus | m phase inducer phosphatasecdc25 | 0.0175 | 0.134 | 0.134 |
Loa Loa (eye worm) | hypothetical protein | 0.0175 | 0.134 | 0.134 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0593 | 0.5351 | 0.5351 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0593 | 0.5351 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0593 | 0.5351 | 0.5351 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0133 | 0.0941 | 0.1759 |
Plasmodium falciparum | serine repeat antigen 6 | 0.0133 | 0.0941 | 0.1759 |
Onchocerca volvulus | 0.0593 | 0.5351 | 1 | |
Plasmodium vivax | serine-repeat antigen 2 (SERA) | 0.0133 | 0.0941 | 0.1759 |
Brugia malayi | Cathepsin L-like precursor | 0.0593 | 0.5351 | 0.5351 |
Brugia malayi | Cathepsin L-like precursor | 0.0186 | 0.1451 | 0.1451 |
Echinococcus granulosus | geminin | 0.0178 | 0.1374 | 0.1374 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0233 | 0.1896 | 0.1896 |
Giardia lamblia | Cathepsin B precursor | 0.0133 | 0.0941 | 0.2515 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0319 | 0.2729 | 0.2729 |
Echinococcus multilocularis | cysteine protease | 0.0593 | 0.5351 | 0.5351 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0593 | 0.5351 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0061 | 0.0253 | 0.0253 |
Plasmodium vivax | dipeptidyl aminopeptidase 1, putative | 0.0133 | 0.0941 | 0.1759 |
Echinococcus granulosus | cathepsin l1 | 0.0593 | 0.5351 | 0.5351 |
Plasmodium vivax | vivapain-3 | 0.0319 | 0.2729 | 0.51 |
Loa Loa (eye worm) | hypothetical protein | 0.0186 | 0.1451 | 0.1451 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0186 | 0.1451 | 0.1451 |
Chlamydia trachomatis | pyruvate kinase | 0.0035 | 0 | 0.5 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0593 | 0.5351 | 0.5351 |
Leishmania major | cathepsin L-like protease | 0.0593 | 0.5351 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1077 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase 1, putative | 0.0319 | 0.2729 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0133 | 0.0941 | 0.1759 |
Mycobacterium ulcerans | pyruvate kinase | 0.0035 | 0 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0133 | 0.0941 | 0.1759 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0133 | 0.0941 | 0.1759 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0593 | 0.5351 | 1 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0061 | 0.0253 | 0.0253 |
Giardia lamblia | Cathepsin B precursor | 0.0425 | 0.3743 | 1 |
Brugia malayi | cathepsin L-like cysteine proteinase, identical | 0.0186 | 0.1451 | 0.1451 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0726 | 0.663 | 0.663 |
Trichomonas vaginalis | cdc25b, putative | 0.0175 | 0.134 | 0.2504 |
Brugia malayi | Rhodanese-like domain containing protein | 0.0175 | 0.134 | 0.134 |
Giardia lamblia | Cathepsin B precursor | 0.0133 | 0.0941 | 0.2515 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0593 | 0.5351 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0593 | 0.5351 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0593 | 0.5351 | 0.5351 |
Loa Loa (eye worm) | hypothetical protein | 0.0133 | 0.0941 | 0.0941 |
Plasmodium falciparum | dipeptidyl aminopeptidase 1 | 0.0133 | 0.0941 | 0.1759 |
Loa Loa (eye worm) | hypothetical protein | 0.0133 | 0.0941 | 0.0941 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0319 | 0.2729 | 0.2729 |
Loa Loa (eye worm) | hypothetical protein | 0.0161 | 0.1209 | 0.1209 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0186 | 0.1451 | 0.1451 |
Brugia malayi | cathepsin Z-like cysteine proteinase | 0.0133 | 0.0941 | 0.0941 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0319 | 0.2729 | 0.51 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0319 | 0.2729 | 0.2729 |
Giardia lamblia | Cathepsin L precursor | 0.0133 | 0.0941 | 0.2515 |
Loa Loa (eye worm) | hypothetical protein | 0.0186 | 0.1451 | 0.1451 |
Schistosoma mansoni | cathepsin B (C01 family) | 0.0133 | 0.0941 | 0.0941 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0593 | 0.5351 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0593 | 0.5351 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0319 | 0.2729 | 0.4054 |
Brugia malayi | Cathepsin L-like precursor | 0.0593 | 0.5351 | 0.5351 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0319 | 0.2729 | 0.51 |
Schistosoma mansoni | subfamily C1A unassigned peptidase (C01 family) | 0.0133 | 0.0941 | 0.0941 |
Giardia lamblia | Cathepsin B precursor | 0.0425 | 0.3743 | 1 |
Leishmania major | cathepsin L-like protease | 0.0593 | 0.5351 | 1 |
Toxoplasma gondii | preprocathepsin c precursor, putative | 0.0133 | 0.0941 | 0.1759 |
Leishmania major | cathepsin L-like protease | 0.0593 | 0.5351 | 1 |
Echinococcus granulosus | cathepsin b | 0.1077 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0593 | 0.5351 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0133 | 0.0941 | 0.0941 |
Toxoplasma gondii | cathepsin CPL | 0.0593 | 0.5351 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0593 | 0.5351 | 0.5351 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0319 | 0.2729 | 0.2729 |
Plasmodium vivax | unspecified product | 0.0133 | 0.0941 | 0.1759 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0593 | 0.5351 | 1 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0406 | 0.3563 | 0.3563 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0593 | 0.5351 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0593 | 0.5351 | 0.5351 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0593 | 0.5351 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0593 | 0.5351 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0593 | 0.5351 | 1 |
Echinococcus granulosus | cysteine protease | 0.0319 | 0.2729 | 0.2729 |
Giardia lamblia | Cathepsin B precursor | 0.0425 | 0.3743 | 1 |
Giardia lamblia | Encystation-specific protease | 0.0133 | 0.0941 | 0.2515 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0593 | 0.5351 | 1 |
Loa Loa (eye worm) | TAR-binding protein | 0.0061 | 0.0253 | 0.0253 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0133 | 0.0941 | 0.1759 |
Onchocerca volvulus | 0.0175 | 0.134 | 0.2504 | |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0133 | 0.0941 | 0.0941 |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.0186 | 0.1451 | 0.1451 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0061 | 0.0253 | 0.0253 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0186 | 0.1451 | 0.1451 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0133 | 0.0941 | 0.0941 |
Giardia lamblia | Cathepsin L precursor | 0.0133 | 0.0941 | 0.2515 |
Entamoeba histolytica | cysteine protease, putative | 0.0319 | 0.2729 | 0.4054 |
Onchocerca volvulus | 0.0047 | 0.0119 | 0.0222 | |
Entamoeba histolytica | cysteine proteinase, putative | 0.0319 | 0.2729 | 0.4054 |
Onchocerca volvulus | Cathepsin F homolog | 0.0593 | 0.5351 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0406 | 0.3563 | 0.6659 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0319 | 0.2729 | 0.4054 |
Schistosoma mansoni | cathepsin S (C01 family) | 0.0133 | 0.0941 | 0.0941 |
Schistosoma mansoni | hypothetical protein | 0.0178 | 0.1374 | 0.1374 |
Plasmodium falciparum | serine repeat antigen 2 | 0.0133 | 0.0941 | 0.1759 |
Plasmodium falciparum | dipeptidyl aminopeptidase 2 | 0.0133 | 0.0941 | 0.1759 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0593 | 0.5351 | 1 |
Plasmodium vivax | dipeptidyl aminopeptidase 3, putative | 0.0133 | 0.0941 | 0.1759 |
Plasmodium vivax | vivapain-1 | 0.0319 | 0.2729 | 0.51 |
Brugia malayi | cathepsin L-like cysteine proteinase | 0.0133 | 0.0941 | 0.0941 |
Onchocerca volvulus | 0.0133 | 0.0941 | 0.1759 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0425 | 0.3743 | 0.6995 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0726 | 0.663 | 0.663 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0593 | 0.5351 | 0.5351 |
Giardia lamblia | Cathepsin L precursor | 0.0133 | 0.0941 | 0.2515 |
Brugia malayi | cahepsin L-like non-peptiedase homolog | 0.0133 | 0.0941 | 0.0941 |
Schistosoma mansoni | dipeptidyl-peptidase I (C01 family) | 0.0133 | 0.0941 | 0.0941 |
Onchocerca volvulus | 0.0593 | 0.5351 | 1 | |
Echinococcus multilocularis | tar DNA binding protein | 0.0061 | 0.0253 | 0.0253 |
Onchocerca volvulus | 0.0593 | 0.5351 | 1 | |
Onchocerca volvulus | 0.0406 | 0.3563 | 0.6659 | |
Loa Loa (eye worm) | cathepsin B | 0.0425 | 0.3743 | 0.3743 |
Giardia lamblia | Hypothetical protein | 0.0133 | 0.0941 | 0.2515 |
Echinococcus multilocularis | cysteine protease | 0.0593 | 0.5351 | 0.5351 |
Plasmodium falciparum | serine repeat antigen 3 | 0.0133 | 0.0941 | 0.1759 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0593 | 0.5351 | 0.5351 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0593 | 0.5351 | 0.5351 |
Plasmodium falciparum | cysteine proteinase falcipain 1 | 0.0319 | 0.2729 | 0.51 |
Leishmania major | cysteine peptidase A (CPA) | 0.0593 | 0.5351 | 1 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0406 | 0.3563 | 0.3563 |
Entamoeba histolytica | cysteine protease, putative | 0.0319 | 0.2729 | 0.4054 |
Schistosoma mansoni | cathepsin C | 0.0133 | 0.0941 | 0.0941 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0425 | 0.3743 | 0.6995 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0593 | 0.5351 | 1 |
Echinococcus granulosus | tar DNA binding protein | 0.0061 | 0.0253 | 0.0253 |
Echinococcus multilocularis | m phase inducer phosphatase(cdc25) | 0.0175 | 0.134 | 0.134 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0593 | 0.5351 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0133 | 0.0941 | 0.1759 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0593 | 0.5351 | 0.5351 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0593 | 0.5351 | 1 |
Leishmania major | cathepsin L-like protease | 0.0593 | 0.5351 | 1 |
Trichomonas vaginalis | cdc25c, putative | 0.0175 | 0.134 | 0.2504 |
Onchocerca volvulus | 0.0593 | 0.5351 | 1 | |
Toxoplasma gondii | cathepsin B | 0.0425 | 0.3743 | 0.6995 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0593 | 0.5351 | 0.5351 |
Schistosoma mansoni | tar DNA-binding protein | 0.0061 | 0.0253 | 0.0253 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or H-like cysteine peptidase | 0.0133 | 0.0941 | 0.1759 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0133 | 0.0941 | 0.0941 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0233 | 0.1896 | 0.1896 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0319 | 0.2729 | 0.51 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0593 | 0.5351 | 0.5351 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.0119 | 0.0119 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0593 | 0.5351 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0133 | 0.0941 | 0.0941 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0406 | 0.3563 | 0.5946 |
Brugia malayi | RNA binding protein | 0.0061 | 0.0253 | 0.0253 |
Giardia lamblia | Dipeptidyl-peptidase I precursor | 0.0133 | 0.0941 | 0.2515 |
Plasmodium vivax | serine-repeat antigen (SERA), putative | 0.0133 | 0.0941 | 0.1759 |
Echinococcus multilocularis | cathepsin b | 0.1077 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0133 | 0.0941 | 0.0941 |
Echinococcus multilocularis | cathepsin L | 0.0319 | 0.2729 | 0.2729 |
Brugia malayi | cathepsin L precursor | 0.0133 | 0.0941 | 0.0941 |
Brugia malayi | Cathepsin L-like precursor | 0.0406 | 0.3563 | 0.3563 |
Entamoeba histolytica | cysteine protease, putative | 0.0319 | 0.2729 | 0.4054 |
Giardia lamblia | Cysteine protease | 0.0133 | 0.0941 | 0.2515 |
Leishmania major | cathepsin L-like protease | 0.0593 | 0.5351 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0593 | 0.5351 | 1 |
Giardia lamblia | Cysteine protease | 0.0133 | 0.0941 | 0.2515 |
Giardia lamblia | Cathepsin L-like protease | 0.0133 | 0.0941 | 0.2515 |
Trichomonas vaginalis | mitotic inducer phosphatase CDC25, putative | 0.0175 | 0.134 | 0.2504 |
Entamoeba histolytica | rodhanase-like domain containing protein | 0.0175 | 0.134 | 0.0904 |
Plasmodium falciparum | serine repeat antigen 1 | 0.0133 | 0.0941 | 0.1759 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0133 | 0.0941 | 0.1759 |
Loa Loa (eye worm) | hypothetical protein | 0.0233 | 0.1896 | 0.1896 |
Loa Loa (eye worm) | hypothetical protein | 0.0406 | 0.3563 | 0.3563 |
Echinococcus granulosus | cathepsin L | 0.0319 | 0.2729 | 0.2729 |
Plasmodium vivax | vivapain-2 | 0.0593 | 0.5351 | 1 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.1077 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0593 | 0.5351 | 1 |
Loa Loa (eye worm) | ctsf protein | 0.0593 | 0.5351 | 0.5351 |
Schistosoma mansoni | tar DNA-binding protein | 0.0061 | 0.0253 | 0.0253 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0593 | 0.5351 | 1 |
Mycobacterium leprae | Probable pyruvate kinase PykA | 0.0035 | 0 | 0.5 |
Plasmodium falciparum | serine repeat antigen 7 | 0.0133 | 0.0941 | 0.1759 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin F-like cysteine peptidase | 0.0133 | 0.0941 | 0.1759 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0593 | 0.5351 | 1 |
Toxoplasma gondii | cathepsin CPC1 | 0.0133 | 0.0941 | 0.1759 |
Brugia malayi | fibroinase precursor | 0.0133 | 0.0941 | 0.0941 |
Brugia malayi | Rhodanese-like domain containing protein | 0.0175 | 0.134 | 0.134 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0319 | 0.2729 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0133 | 0.0941 | 0.1759 |
Brugia malayi | Cathepsin L-like precursor | 0.0593 | 0.5351 | 0.5351 |
Plasmodium vivax | serine-repeat antigen 3 (SERA) | 0.0133 | 0.0941 | 0.1759 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0593 | 0.5351 | 1 |
Echinococcus granulosus | cathepsin b | 0.1077 | 1 | 1 |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.0133 | 0.0941 | 0.0941 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.0425 | 0.3743 | 0.6995 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0047 | 0.0119 | 0.0119 |
Trichomonas vaginalis | cdc25b, putative | 0.0175 | 0.134 | 0.2504 |
Entamoeba histolytica | rodhanase-like domain containing protein | 0.0175 | 0.134 | 0.0904 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0593 | 0.5351 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0406 | 0.3563 | 0.6659 |
Plasmodium falciparum | dipeptidyl aminopeptidase 3 | 0.0133 | 0.0941 | 0.1759 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.0319 | 0.2729 | 0.2729 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0133 | 0.0941 | 0.0941 |
Giardia lamblia | Cathepsin L precursor | 0.0133 | 0.0941 | 0.2515 |
Plasmodium vivax | serine-repeat antigen (SERA) | 0.0133 | 0.0941 | 0.1759 |
Plasmodium vivax | serine-repeat antigen 5 (SERA) | 0.0133 | 0.0941 | 0.1759 |
Giardia lamblia | Cathepsin L precursor | 0.0133 | 0.0941 | 0.2515 |
Loa Loa (eye worm) | hypothetical protein | 0.0133 | 0.0941 | 0.0941 |
Entamoeba histolytica | cysteine proteinase 2 | 0.0319 | 0.2729 | 0.4054 |
Giardia lamblia | Cathepsin L-like protease | 0.0133 | 0.0941 | 0.2515 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0593 | 0.5351 | 1 |
Giardia lamblia | Cathepsin L precursor | 0.0133 | 0.0941 | 0.2515 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0593 | 0.5351 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0593 | 0.5351 | 0.5351 |
Echinococcus multilocularis | cathepsin b | 0.1077 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1077 | 1 | 1 |
Plasmodium vivax | unspecified product | 0.0186 | 0.1451 | 0.2711 |
Entamoeba histolytica | cysteine protease, putative | 0.0319 | 0.2729 | 0.4054 |
Brugia malayi | Cathepsin L-like precursor | 0.0406 | 0.3563 | 0.3563 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0593 | 0.5351 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0593 | 0.5351 | 1 |
Brugia malayi | TAR-binding protein | 0.0061 | 0.0253 | 0.0253 |
Loa Loa (eye worm) | RNA binding protein | 0.0061 | 0.0253 | 0.0253 |
Entamoeba histolytica | cysteine protease, putative | 0.0319 | 0.2729 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0593 | 0.5351 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0319 | 0.2729 | 0.4054 |
Plasmodium vivax | unspecified product | 0.0319 | 0.2729 | 0.51 |
Onchocerca volvulus | Cathepsin L homolog | 0.0593 | 0.5351 | 1 |
Onchocerca volvulus | 0.0593 | 0.5351 | 1 | |
Loa Loa (eye worm) | fibroinase | 0.0593 | 0.5351 | 0.5351 |
Onchocerca volvulus | Cathepsin L homolog | 0.0593 | 0.5351 | 1 |
Schistosoma mansoni | m-phase inducer phosphatase(cdc25) | 0.0175 | 0.134 | 0.134 |
Leishmania major | cathepsin L-like protease | 0.0593 | 0.5351 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0319 | 0.2729 | 0.4054 |
Trichomonas vaginalis | m-phase inducer phosphatase, putative | 0.0175 | 0.134 | 0.2504 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0319 | 0.2729 | 0.2729 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0133 | 0.0941 | 0.0941 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase | 0.0133 | 0.0941 | 0.1759 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0319 | 0.2729 | 0.2729 |
Trichomonas vaginalis | mitotic inducer phosphatase CDC25, putative | 0.0175 | 0.134 | 0.2504 |
Brugia malayi | cathepsin L-like precursor | 0.0406 | 0.3563 | 0.3563 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0726 | 0.663 | 0.663 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0133 | 0.0941 | 0.1759 |
Trichomonas vaginalis | m-phase inducer phosphatase, putative | 0.0175 | 0.134 | 0.2504 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1077 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0593 | 0.5351 | 0.5351 |
Schistosoma mansoni | survival motor neuron protein | 0.0047 | 0.0119 | 0.0119 |
Loa Loa (eye worm) | hypothetical protein | 0.0406 | 0.3563 | 0.3563 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0133 | 0.0941 | 0.0941 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0133 | 0.0941 | 0.1759 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0593 | 0.5351 | 1 |
Giardia lamblia | Cysteine protease | 0.0133 | 0.0941 | 0.2515 |
Plasmodium vivax | serine-repeat antigen (SERA), putative | 0.0133 | 0.0941 | 0.1759 |
Giardia lamblia | Hypothetical protein | 0.0133 | 0.0941 | 0.2515 |
Loa Loa (eye worm) | hypothetical protein | 0.0406 | 0.3563 | 0.3563 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0593 | 0.5351 | 0.5351 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
EC25 (functional) | = 6 uM | Concentration necessary for increase in time to contracture by 25% in the globally ischemic rat hearts | ChEMBL. | 7650676 |
IC50 (functional) | = 6.3 uM | Tested for the vasorelaxant potency in methoxamine contracted rat aorta | ChEMBL. | 7650676 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.