Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | serine/threonine protein kinase | 0.0266 | 0.6034 | 0.6028 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.003 | 0.0594 | 0.0781 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0594 | 0.0781 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0.0074 | 0.0123 |
Echinococcus granulosus | GPCR family 2 | 0.003 | 0.0594 | 0.0509 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0074 | 0.0123 |
Echinococcus granulosus | cpg binding protein | 0.0033 | 0.0662 | 0.0578 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.0266 | 0.6034 | 0.5998 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0064 | 0.1383 | 0.2122 |
Schistosoma mansoni | cell polarity protein | 0.0012 | 0.0201 | 0.0186 |
Trypanosoma brucei | protein kinase, putative | 0.0266 | 0.6034 | 0.5 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0093 | 0.2063 | 0.3274 |
Echinococcus multilocularis | GPCR, family 2 | 0.003 | 0.0594 | 0.0509 |
Brugia malayi | EGF-like domain containing protein | 0.0012 | 0.0201 | 0.012 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0074 | 0.0123 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.003 | 0.0594 | 0.0509 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0074 | 0.0123 |
Schistosoma mansoni | cpg binding protein | 0.0033 | 0.0662 | 0.0648 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.0266 | 0.6034 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0201 | 0.0115 |
Schistosoma mansoni | hypothetical protein | 0.0064 | 0.1383 | 0.137 |
Brugia malayi | Thrombospondin N-terminal -like domain containing protein | 0.0012 | 0.0201 | 0.012 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0074 | 0.0123 |
Echinococcus granulosus | slit 2 protein | 0.0012 | 0.0201 | 0.0112 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0093 | 0.2063 | 0.3271 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0201 | 0.0115 |
Schistosoma mansoni | hypothetical protein | 0.003 | 0.0594 | 0.0579 |
Echinococcus granulosus | mitogen activated protein kinase | 0.0266 | 0.6034 | 0.5998 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0065 | 0.1416 | 0.1403 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0074 | 0.0123 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0266 | 0.6034 | 1 |
Echinococcus multilocularis | cpg binding protein | 0.0033 | 0.0662 | 0.0578 |
Schistosoma mansoni | hypothetical protein | 0.003 | 0.0594 | 0.0579 |
Loa Loa (eye worm) | abnormal epIthelia family member | 0.0012 | 0.0201 | 0.0115 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.003 | 0.0594 | 0.0786 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0074 | 0.0123 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.0266 | 0.6034 | 0.5 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0074 | 0.0123 |
Schistosoma mansoni | laminin gamma-3 chain | 0.0012 | 0.0201 | 0.0186 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0093 | 0.2063 | 0.3274 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.0266 | 0.6034 | 0.5998 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0074 | 0.0123 |
Giardia lamblia | Kinase, CMGC MAPK | 0.0266 | 0.6034 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0201 | 0.0115 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.0622 | 0.0608 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.003 | 0.0594 | 0.0509 |
Echinococcus multilocularis | pikachurin | 0.0012 | 0.0201 | 0.0112 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.003 | 0.0594 | 0.0509 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0438 | 1 | 1 |
Brugia malayi | laminin alpha chain | 0.0012 | 0.0201 | 0.012 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0.0074 | 0.0123 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.0266 | 0.6034 | 1 |
Brugia malayi | Latrophilin receptor protein 2 | 0.003 | 0.0594 | 0.0786 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.003 | 0.0594 | 0.0509 |
Trichomonas vaginalis | helicase, putative | 0.0007 | 0.0074 | 0.0123 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0074 | 0.0123 |
Brugia malayi | laminin-like protein K08C7.3 precursor | 0.0012 | 0.0201 | 0.012 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.2063 | 0.3271 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.1383 | 0.2119 |
Schistosoma mansoni | hypothetical protein | 0.0438 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0074 | 0.0123 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0008 | 0.009 | 0.0074 |
Onchocerca volvulus | 0.0031 | 0.0622 | 0.5 | |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.0266 | 0.6034 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.003 | 0.0594 | 0.0579 |
Brugia malayi | CXXC zinc finger family protein | 0.0031 | 0.0622 | 0.0833 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0266 | 0.6034 | 0.5 |
Brugia malayi | MAP kinase sur-1 | 0.0266 | 0.6034 | 1 |
Schistosoma mansoni | slit | 0.0012 | 0.0201 | 0.0186 |
Echinococcus granulosus | pikachurin | 0.0012 | 0.0201 | 0.0112 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.0266 | 0.6034 | 0.5 |
Echinococcus multilocularis | neurogenic locus notch protein | 0.0012 | 0.0201 | 0.0112 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0074 | 0.0123 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0074 | 0.0123 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.001 | 0.0133 | 0.0044 |
Echinococcus multilocularis | slit 2 protein | 0.0012 | 0.0201 | 0.0112 |
Echinococcus granulosus | neurogenic locus notch protein | 0.0012 | 0.0201 | 0.0112 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.0266 | 0.6034 | 0.5998 |
Schistosoma mansoni | hypothetical protein | 0.003 | 0.0594 | 0.0579 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0074 | 0.0123 |
Schistosoma mansoni | cpg binding protein | 0.0033 | 0.0662 | 0.0648 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0074 | 0.0123 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0074 | 0.0123 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0266 | 0.6034 | 1 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.0266 | 0.6034 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0266 | 0.6034 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0266 | 0.6034 | 1 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.0266 | 0.6034 | 0.5 |
Schistosoma mansoni | chondroitin sulfate proteoglycan-related | 0.0012 | 0.0201 | 0.0186 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.001 | 0.0133 | 0.0044 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0031 | 0.0622 | 0.0829 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0266 | 0.6034 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.