Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0602 | 0.0602 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0058 | 0.0998 | 0.0998 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.0477 | 1 | 0.5 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.0477 | 1 | 0.5 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.0477 | 1 | 1 |
Echinococcus granulosus | GPCR family 2 | 0.0018 | 0.0142 | 0.0142 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.0477 | 1 | 0.5 |
Onchocerca volvulus | 0.0012 | 0 | 0.5 | |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0142 | 0.0142 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0018 | 0.0142 | 0.0142 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0142 | 0.0142 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0018 | 0.0142 | 0.0142 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0477 | 1 | 0.5 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0018 | 0.0142 | 0.0142 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.0477 | 1 | 0.5 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0018 | 0.0142 | 0.0142 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0058 | 0.0998 | 0.0998 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0142 | 0.0142 |
Trypanosoma brucei | protein kinase, putative | 0.0477 | 1 | 0.5 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0018 | 0.0142 | 0.0142 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0477 | 1 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0477 | 1 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0142 | 0.0142 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.0477 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.0998 | 0.0998 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0477 | 1 | 0.5 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0012 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0142 | 0.0142 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.0477 | 1 | 1 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.004 | 0.0602 | 0.0602 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0058 | 0.0998 | 0.0998 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0012 | 0 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0602 | 0.0602 |
Giardia lamblia | Kinase, CMGC MAPK | 0.0477 | 1 | 0.5 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.0477 | 1 | 1 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0012 | 0 | 0.5 |
Echinococcus granulosus | mitogen activated protein kinase | 0.0477 | 1 | 1 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0018 | 0.0142 | 0.0142 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0477 | 1 | 0.5 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0477 | 1 | 1 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.0477 | 1 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0477 | 1 | 0.5 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0018 | 0.0142 | 0.0142 |
Echinococcus multilocularis | GPCR, family 2 | 0.0018 | 0.0142 | 0.0142 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.0477 | 1 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.