Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | tumor necrosis factor | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.2052 | 0.8469 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.2316 | 1 | 0.5 |
Trypanosoma brucei | adenosine kinase, putative | 0.2316 | 1 | 1 |
Toxoplasma gondii | kinase, pfkB family protein | 0.2316 | 1 | 0.5 |
Echinococcus granulosus | adenosine kinase | 0.2316 | 1 | 0.5 |
Leishmania major | adenosine kinase, putative | 0.2316 | 1 | 0.5 |
Schistosoma mansoni | adenosine kinase | 0.2316 | 1 | 1 |
Echinococcus multilocularis | adenosine kinase | 0.2316 | 1 | 0.5 |
Trypanosoma cruzi | adenosine kinase, putative | 0.2316 | 1 | 0.5 |
Trypanosoma cruzi | adenosine kinase, putative | 0.2316 | 1 | 0.5 |
Schistosoma mansoni | adenosine kinase | 0.2316 | 1 | 1 |
Trypanosoma brucei | adenosine kinase, putative | 0.2316 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.