Detailed information for compound 1817608

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 579.306 | Formula: C26H17Br2N3OS
  • H donors: 1 H acceptors: 3 LogP: 6.99 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 2
  • SMILES: N#Cc1c(SCC(=O)Nc2ccc(cc2)Br)nc(cc1c1cccc(c1)Br)c1ccccc1
  • InChi: 1S/C26H17Br2N3OS/c27-19-9-11-21(12-10-19)30-25(32)16-33-26-23(15-29)22(18-7-4-8-20(28)13-18)14-24(31-26)17-5-2-1-3-6-17/h1-14H,16H2,(H,30,32)
  • InChiKey: MGQOLMWGPBXLPB-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0012 0.0011 0.001
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0012 0.0011 0.0011
Brugia malayi MH2 domain containing protein 0.0136 0.0871 0.0903
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0012 0.0011 0.0011
Loa Loa (eye worm) transcription factor SMAD2 0.0136 0.0871 0.0902
Echinococcus multilocularis dihydrolipoyllysine residue acetyltransferase 0.0051 0.0284 0.0283
Echinococcus multilocularis cpg binding protein 0.0035 0.017 0.0169
Brugia malayi Cytochrome P450 family protein 0.0016 0.0042 0.0044
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0012 0.0011 0.001
Echinococcus multilocularis thyroid hormone receptor alpha 0.0012 0.0011 0.001
Schistosoma mansoni propionyl-CoA carboxylase beta chain mitochondrial precursor 0.0198 0.1295 0.1286
Mycobacterium tuberculosis Acetyl/propionyl-CoA carboxylase (beta subunit) AccD6 0.0198 0.1295 0.3365
Plasmodium falciparum biotin carboxylase subunit of acetyl CoA carboxylase, putative 0.1058 0.7218 1
Brugia malayi Cytochrome P450 family protein 0.0016 0.0042 0.0044
Toxoplasma gondii dihydrolipoamide acyltransferase, putative 0.0051 0.0284 0.0242
Wolbachia endosymbiont of Brugia malayi Acetyl-CoA carboxylase, carboxyltransferase component 0.0198 0.1295 0.2905
Schistosoma mansoni methylcrotonyl-CoA carboxylase 0.0557 0.3766 0.376
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0012 0.0011 0.001
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0012 0.0011 0.001
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0012 0.0011 0.0011
Mycobacterium tuberculosis Probable branched-chain keto acid dehydrogenase E2 component BkdC 0.0051 0.0284 0.0648
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0012 0.0011 0.001
Mycobacterium leprae Probable bifunctional protein acetyl-/propionyl-coenzyme A carboxylase, alpha chain AccA3 (BccP) 0.0557 0.3766 1
Schistosoma mansoni hypothetical protein 0.0018 0.0055 0.0045
Schistosoma mansoni dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase 0.0051 0.0284 0.0273
Loa Loa (eye worm) hypothetical protein 0.0012 0.0011 0.001
Toxoplasma gondii histone lysine methyltransferase SET1 0.0062 0.0359 0.0318
Leishmania major acetyl-CoA carboxylase, putative 0.1462 1 1
Echinococcus granulosus dnaJ subfamily B 0.0468 0.3152 0.3152
Echinococcus multilocularis FTZ F1 alpha 0.0012 0.0011 0.001
Brugia malayi nuclear receptor NHR-88 0.0012 0.0011 0.0011
Schistosoma mansoni carbamoyl-phosphate synthetase 0.0126 0.0798 0.0788
Mycobacterium tuberculosis Probable acetyl-/propionyl-coenzyme A carboxylase alpha chain (alpha subunit) AccA2: biotin carboxylase + biotin carboxyl carrie 0.0557 0.3766 1
Echinococcus granulosus dihydrolipoyllysine residue succinyltransferase 0.0051 0.0284 0.0283
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0012 0.0011 0.0011
Echinococcus granulosus cytochrome P450 2K1 0.0016 0.0042 0.0042
Echinococcus granulosus propionyl coenzyme A carboxylase beta chain 0.0198 0.1295 0.1295
Mycobacterium ulcerans propionyl-CoA carboxylase beta chain 4 AccD4 0.0198 0.1295 0.3365
Trypanosoma brucei 3-methylcrotonyl-CoA carboxylase alpha subunit, putative 0.0557 0.3766 0.374
Toxoplasma gondii 2-oxo acid dehydrogenases acyltransferase (catalytic domain) domain-containing protein 0.0051 0.0284 0.0242
Loa Loa (eye worm) hypothetical protein 0.0012 0.0011 0.001
Trypanosoma brucei 3-methylcrotonoyl-CoA carboxylase beta subunit, putative 0.0198 0.1295 0.1258
Loa Loa (eye worm) CYP4Cod1 0.0016 0.0042 0.0043
Trypanosoma cruzi dihydrolipoamide branched chain transacylase, putative 0.0051 0.0284 0.0394
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0012 0.0011 0.0011
Mycobacterium ulcerans hypothetical protein 0.0051 0.0284 0.0648
Leishmania major carboxylase, putative 0.0557 0.3766 0.374
Toxoplasma gondii acetyl-CoA carboxylase ACC1 0.1462 1 1
Mycobacterium ulcerans acetyl-/propionyl-CoA carboxylase subunit beta 0.0198 0.1295 0.3365
Schistosoma mansoni hypothetical protein 0.0018 0.0055 0.0045
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0012 0.0011 0.0011
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0012 0.0011 0.001
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0018 0.0055 0.0054
Loa Loa (eye worm) hypothetical protein 0.0012 0.0011 0.001
Brugia malayi Cytochrome P450 family protein 0.0016 0.0042 0.0044
Leishmania major methylcrotonoyl-coa carboxylase biotinylated subunitprotein-like protein 0.0557 0.3766 0.374
Trypanosoma cruzi 3-methylcrotonoyl-CoA carboxylase beta subunit, putative 0.0198 0.1295 0.2047
Brugia malayi latrophilin 2 splice variant baaae 0.0039 0.0199 0.0207
Trypanosoma cruzi acetyl-CoA carboxylase, putative 0.0198 0.1295 0.2047
Schistosoma mansoni dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase 0.0051 0.0284 0.0273
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0012 0.0011 0.0011
Trypanosoma cruzi 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase, putative 0.0051 0.0284 0.0394
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0012 0.0011 0.0011
Brugia malayi Steroid receptor seven-up type 2 0.0012 0.0011 0.0011
Echinococcus multilocularis microtubule associated protein 2 0.0789 0.5366 0.5365
Schistosoma mansoni hypothetical protein 0.0016 0.0042 0.0032
Loa Loa (eye worm) MH2 domain-containing protein 0.0136 0.0871 0.0902
Brugia malayi Cytochrome P450 family protein 0.006 0.0343 0.0355
Loa Loa (eye worm) latrophilin receptor protein 2 0.0018 0.0055 0.0056
Loa Loa (eye worm) hypothetical protein 0.0039 0.0199 0.0206
Mycobacterium leprae ACETYL/PROPIONYL-CoA CARBOXYLASE (BETA SUBUNIT) ACCD6 0.0198 0.1295 0.3365
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0012 0.0011 0.001
Onchocerca volvulus 0.0033 0.0157 1
Mycobacterium ulcerans acetyl-/propionyl-coenzyme a carboxylase alpha chain AccA1 0.0557 0.3766 1
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0018 0.0055 0.0057
Echinococcus multilocularis dnaJ subfamily B 0.0468 0.3152 0.3152
Echinococcus multilocularis acetyl coenzyme A carboxylase 1 0.1462 1 1
Mycobacterium ulcerans branched-chain alpha-keto acid dehydrogenase subunit E2 0.0051 0.0284 0.0648
Echinococcus multilocularis propionyl coenzyme A carboxylase beta chain 0.0198 0.1295 0.1295
Brugia malayi Latrophilin receptor protein 2 0.0018 0.0055 0.0057
Leishmania major dihydrolipoamide acetyltransferase precursorlike protein 0.0051 0.0284 0.0242
Echinococcus multilocularis ecdysone induced protein 78C 0.0012 0.0011 0.001
Toxoplasma gondii acetyl-coA carboxylase ACC2 0.1462 1 1
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0012 0.0011 0.001
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0012 0.0011 0.001
Echinococcus multilocularis 0.0016 0.0042 0.0042
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0012 0.0011 0.0011
Brugia malayi cytochrome P450 0.0016 0.0042 0.0044
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0012 0.0011 0.001
Wolbachia endosymbiont of Brugia malayi Acetyl/propionyl-CoA carboxylase, alpha subunit 0.0557 0.3766 1
Brugia malayi Nuclear hormone receptor-like 1 0.0012 0.0011 0.0011
Plasmodium vivax carbamoyl phosphate synthetase, putative 0.0126 0.0798 0.0742
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0018 0.0055 0.0054
Loa Loa (eye worm) carboxyl transferase domain-containing protein 0.141 0.9647 1
Schistosoma mansoni carbamoyl-phosphate synthetase 0.0126 0.0798 0.0788
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0057 0.0324 0.0334
Loa Loa (eye worm) hypothetical protein 0.0012 0.0011 0.001
Mycobacterium leprae Probable biotinylated protein homolog TB7.3 0.0051 0.0284 0.0648
Schistosoma mansoni aspartate carbamoyltransferase 0.0126 0.0798 0.0788
Schistosoma mansoni hypothetical protein 0.0039 0.0199 0.0189
Mycobacterium ulcerans bifunctional protein acetyl-/propionyl-coenzyme a carboxylase (alpha chain) AccA3 0.0557 0.3766 1
Loa Loa (eye worm) hypothetical protein 0.0057 0.0324 0.0334
Trypanosoma brucei 3-methylcrotonyl-CoA carboxylase alpha subunit, putative 0.0557 0.3766 0.374
Loa Loa (eye worm) CXXC zinc finger family protein 0.0033 0.0157 0.0162
Mycobacterium ulcerans dihydrolipoamide acetyltransferase 0.0051 0.0284 0.0648
Trypanosoma cruzi 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase, putative 0.0051 0.0284 0.0394
Brugia malayi dihydrolipoamide S-acetyltransferase precursor, putative 0.0051 0.0284 0.0294
Schistosoma mansoni cytochrome P450 0.0016 0.0042 0.0032
Loa Loa (eye worm) hypothetical protein 0.0051 0.0284 0.0293
Mycobacterium leprae Probable propyonyl-CoA carboxylase beta chain 4 AccD4 (Pccase) 0.0198 0.1295 0.3365
Giardia lamblia Acetyl-CoA carboxylase/pyruvate carboxylase fusion protein, putative 0.0249 0.1648 0.5
Mycobacterium tuberculosis DlaT, dihydrolipoamide acyltransferase, E2 component of pyruvate dehydrogenase 0.0051 0.0284 0.0648
Leishmania major 3-methylcrotonoyl-CoA carboxylase beta subunit, putative 0.0198 0.1295 0.1258
Echinococcus granulosus propionyl coenzyme A carboxylase alpha chain 0.0557 0.3766 0.3766
Trypanosoma brucei 2-oxoglutarate dehydrogenase E2 component, putative 0.0051 0.0284 0.0242
Chlamydia trachomatis acetyl-coenzyme A carboxylase carboxyl transferase subunit beta 0.0198 0.1295 0.3233
Trypanosoma brucei dihydrolipoamide branched chain transacylase, putative 0.0051 0.0284 0.0242
Mycobacterium ulcerans acetyl/propionyl CoA carboxylase subunit beta 0.0198 0.1295 0.3365
Trypanosoma cruzi 3-methylcrotonyl-CoA carboxylase, putative 0.0557 0.3766 0.6083
Trypanosoma cruzi acetyl-CoA carboxylase 0.0905 0.6165 1
Trypanosoma brucei pyruvate dehydrogenase complex E3 binding protein, putative 0.0051 0.0284 0.0242
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0012 0.0011 0.001
Schistosoma mansoni acetyl-CoA carboxylase 0.1462 1 1
Trypanosoma cruzi 3-methylcrotonyl-CoA carboxylase, putative 0.0557 0.3766 0.6083
Loa Loa (eye worm) cytochrome P450 0.0016 0.0042 0.0043
Echinococcus multilocularis propionyl coenzyme A carboxylase alpha chain 0.0557 0.3766 0.3766
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0012 0.0011 0.001
Loa Loa (eye worm) steroid hormone receptor 0.0012 0.0011 0.001
Brugia malayi Carboxyl transferase domain containing protein 0.141 0.9647 1
Mycobacterium tuberculosis Probable pyruvate carboxylase Pca (pyruvic carboxylase) 0.0557 0.3766 1
Trypanosoma cruzi dihydrolipoamide branched chain transacylase, putative 0.0051 0.0284 0.0394
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0012 0.0011 0.001
Loa Loa (eye worm) hypothetical protein 0.0012 0.0011 0.001
Mycobacterium ulcerans carbamoyl phosphate synthase large subunit 0.0126 0.0798 0.2029
Schistosoma mansoni hypothetical protein 0.0018 0.0055 0.0045
Mycobacterium tuberculosis Biotinylated protein TB7.3 0.0051 0.0284 0.0648
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0057 0.0324 0.0335
Mycobacterium ulcerans acetyl-/propionyl-coenzyme a carboxylase alpha chain, AccA2 0.0557 0.3766 1
Schistosoma mansoni cpg binding protein 0.0035 0.017 0.016
Schistosoma mansoni mixed-lineage leukemia protein mll 0.007 0.0411 0.0401
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0012 0.0011 0.001
Echinococcus granulosus GPCR family 2 0.0018 0.0055 0.0054
Echinococcus granulosus FTZ F1 alpha 0.0012 0.0011 0.001
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0012 0.0011 0.001
Loa Loa (eye worm) hypothetical protein 0.0012 0.0011 0.001
Mycobacterium leprae Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex SucB 0.0051 0.0284 0.0648
Trypanosoma cruzi dihydrolipoamide acetyltransferase, putative 0.0051 0.0284 0.0394
Loa Loa (eye worm) cytochrome P450 family protein 0.0016 0.0042 0.0043
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0012 0.0011 0.001
Echinococcus granulosus ecdysone induced protein 78C 0.0012 0.0011 0.001
Mycobacterium leprae Probable propionyl-CoA carboxylase beta chain 5 AccD5 (PCCASE) (PROPANOYL-COA:CARBON DIOXIDE LIGASE) 0.0198 0.1295 0.3365
Brugia malayi Lipoamide acyltransferase component of branched-chain alpha-keto aciddehydrogenase complex, mitochondrial precursor 0.0051 0.0284 0.0294
Schistosoma mansoni cpg binding protein 0.0035 0.017 0.016
Chlamydia trachomatis biotin carboxylase 0.0506 0.3414 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0012 0.0011 0.001
Echinococcus granulosus Biotin lipoyl attachment 0.0051 0.0284 0.0283
Leishmania major 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase, putative 0.0051 0.0284 0.0242
Loa Loa (eye worm) hypothetical protein 0.0051 0.0284 0.0293
Brugia malayi Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial precursor, puta 0.0051 0.0284 0.0294
Leishmania major dihydrolipoamide acetyltransferase precursor, putative 0.0051 0.0284 0.0242
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0018 0.0055 0.0054
Brugia malayi Calcitonin receptor-like protein seb-1 0.0057 0.0324 0.0335
Trypanosoma brucei unspecified product 0.0366 0.2452 0.242
Brugia malayi photoreceptor-specific nuclear receptor 0.0012 0.0011 0.0011
Trypanosoma brucei acetyl-CoA carboxylase 0.1462 1 1
Echinococcus granulosus microtubule associated protein 2 0.0789 0.5366 0.5365
Trypanosoma cruzi glutamine-dependent carbamoyl-phosphate synthetase, putative 0.0126 0.0798 0.1234
Schistosoma mansoni pyruvate carboxylase 0.0557 0.3766 0.376
Schistosoma mansoni hypothetical protein 0.0468 0.3152 0.3145
Trypanosoma cruzi dihydrolipoamide acetyltransferase precursor, putative 0.0051 0.0284 0.0394
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0012 0.0011 0.001
Schistosoma mansoni hypothetical protein 0.0018 0.0055 0.0045
Toxoplasma gondii biotin-requiring enzyme domain-containing protein 0.0051 0.0284 0.0242
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0012 0.0011 0.001
Loa Loa (eye worm) cytochrome P450 family protein 0.0016 0.0042 0.0043
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E2 0.0051 0.0284 0.0242
Mycobacterium ulcerans propionyl-CoA carboxylase beta chain 4 AccD4_2 0.0198 0.1295 0.3365
Plasmodium falciparum carbamoyl phosphate synthetase 0.0126 0.0798 0.0742
Toxoplasma gondii pyruvate carboxylase 0.0557 0.3766 0.374
Loa Loa (eye worm) hypothetical protein 0.0012 0.0011 0.001
Loa Loa (eye worm) hypothetical protein 0.0051 0.0284 0.0293
Trypanosoma cruzi dihydrolipoamide acetyltransferase precursor, putative 0.0051 0.0284 0.0394
Leishmania major propionyl-coa carboxylase beta chain, putative 0.0198 0.1295 0.1258
Wolbachia endosymbiont of Brugia malayi carbamoyl phosphate synthase large subunit 0.0126 0.0798 0.1476
Toxoplasma gondii carbamoylphosphate synthetase 0.0126 0.0798 0.0759
Schistosoma mansoni microtubule-associated protein tau 0.0789 0.5366 0.5361
Trypanosoma brucei glutamine hydrolysing (not ammonia-dependent) carbomoyl phosphate synthase, putative 0.0126 0.0798 0.0759
Brugia malayi steroid hormone receptor 0.0012 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0012 0.0011 0.001
Brugia malayi nuclear hormone receptor 0.0012 0.0011 0.0011
Toxoplasma gondii acyl-CoA carboxyltransferase beta chain, putative 0.0198 0.1295 0.1258
Treponema pallidum pyruvate carboxylase subunit B 0.0051 0.0284 0.5
Trypanosoma cruzi glutamine dependent carbamoyl-phosphate synthase, putative 0.0126 0.0798 0.1234
Loa Loa (eye worm) cytochrome P450 family protein 0.006 0.0343 0.0355
Leishmania major dihydrolipoamide branched chain transacylase, putative 0.0051 0.0284 0.0242
Trypanosoma brucei dihydrolipoamide acetyltransferase E2 subunit, putative 0.0051 0.0284 0.0242
Mycobacterium ulcerans propionyl-CoA carboxylase beta chain 5 AccD5 0.0198 0.1295 0.3365
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0012 0.0011 0.0011
Schistosoma mansoni dihydrolipoamide S-acetyltransferase 0.0051 0.0284 0.0273
Mycobacterium ulcerans acetyl-coenzyme a carboxylase carboxyl transferase (subunit beta) AccD3 0.0198 0.1295 0.3365
Echinococcus multilocularis dihydrolipoyllysine residue succinyltransferase 0.0051 0.0284 0.0283
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0012 0.0011 0.0011
Echinococcus multilocularis Biotin lipoyl attachment 0.0051 0.0284 0.0283
Entamoeba histolytica acetyl-coA carboxylase, putative 0.0249 0.1648 0.5
Brugia malayi CXXC zinc finger family protein 0.0033 0.0157 0.0163
Echinococcus granulosus dihydrolipoyllysine residue acetyltransferase 0.0051 0.0284 0.0283
Schistosoma mansoni methylcrotonyl-CoA carboxylase 0.0557 0.3766 0.376
Schistosoma mansoni dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase 0.0051 0.0284 0.0273
Echinococcus granulosus cpg binding protein 0.0035 0.017 0.0169
Mycobacterium ulcerans pyruvate carboxylase 0.0557 0.3766 1
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0012 0.0011 0.0011
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0012 0.0011 0.001
Schistosoma mansoni cpg binding protein 0.0033 0.0157 0.0147
Mycobacterium tuberculosis Probable propionyl-CoA carboxylase beta chain 5 AccD5 (pccase) (propanoyl-CoA:carbon dioxide ligase) 0.0198 0.1295 0.3365
Echinococcus multilocularis GPCR, family 2 0.0018 0.0055 0.0054
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0012 0.0011 0.0011
Toxoplasma gondii dihydrolipoyllysine-residue succinyltransferase component of oxoglutarate dehydrogenase 0.0051 0.0284 0.0242
Trypanosoma cruzi 3-methylcrotonoyl-CoA carboxylase beta subunit, putative 0.0198 0.1295 0.2047
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0018 0.0055 0.0054
Leishmania major carbamoyl-phosphate synthase, putative 0.0126 0.0798 0.0759
Brugia malayi ecdysteroid receptor 0.0012 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0018 0.0055 0.0056
Plasmodium vivax biotin carboxylase subunit of acetyl CoA carboxylase, putative 0.1058 0.7218 1

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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