Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | hypothetical protein | 0.041 | 0.1071 | 0.1071 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0775 | 1 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0775 | 1 | 1 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0775 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0775 | 1 | 1 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0775 | 1 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0775 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0775 | 1 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0775 | 1 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0775 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0775 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.041 | 0.1071 | 0.1071 |
Brugia malayi | nuclear receptor NHR-88 | 0.0775 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0775 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0775 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.041 | 0.1071 | 0.1071 |
Brugia malayi | nuclear hormone receptor | 0.0775 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.041 | 0.1071 | 0.1071 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0775 | 1 | 1 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0775 | 1 | 1 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0775 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0775 | 1 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0775 | 1 | 1 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0775 | 1 | 1 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0775 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.041 | 0.1071 | 0.1071 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0775 | 1 | 1 |
Echinococcus granulosus | FTZ F1 alpha | 0.0775 | 1 | 1 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0775 | 1 | 1 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0775 | 1 | 1 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0775 | 1 | 1 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.041 | 0.1071 | 0.1071 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0775 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0775 | 1 | 1 |
Echinococcus multilocularis | tumor protein p63 | 0.0369 | 0.0075 | 0.0075 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0775 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0775 | 1 | 1 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.041 | 0.1071 | 0.1071 |
Loa Loa (eye worm) | hypothetical protein | 0.0775 | 1 | 1 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0775 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0775 | 1 | 1 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0775 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0775 | 1 | 1 |
Brugia malayi | nuclear receptor RXR | 0.041 | 0.1071 | 0.1071 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0775 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0775 | 1 | 1 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0775 | 1 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0775 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0775 | 1 | 1 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0775 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0775 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0775 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0775 | 1 | 1 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0775 | 1 | 1 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0775 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.041 | 0.1071 | 0.1071 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0775 | 1 | 1 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0775 | 1 | 1 |
Onchocerca volvulus | 0.0775 | 1 | 1 | |
Schistosoma mansoni | nuclear hormone receptor | 0.0775 | 1 | 1 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0775 | 1 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0775 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.041 | 0.1071 | 0.1071 |
Brugia malayi | hypothetical protein | 0.041 | 0.1071 | 0.1071 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0775 | 1 | 1 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0775 | 1 | 1 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0775 | 1 | 1 |
Schistosoma mansoni | coup transcription factor | 0.0775 | 1 | 1 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0775 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0775 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.041 | 0.1071 | 0.1071 |
Echinococcus granulosus | tumor protein p63 | 0.0369 | 0.0075 | 0.0075 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.041 | 0.1071 | 0.1071 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.041 | 0.1071 | 0.1071 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0775 | 1 | 1 |
Brugia malayi | steroid hormone receptor | 0.0775 | 1 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0775 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0775 | 1 | 1 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.041 | 0.1071 | 0.1071 |
Loa Loa (eye worm) | hypothetical protein | 0.0775 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0775 | 1 | 1 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0775 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0775 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0775 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0775 | 1 | 1 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0775 | 1 | 1 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0775 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.