Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0054 | 0.0198 | 0.0198 |
Onchocerca volvulus | Deterin homolog | 0.0894 | 1 | 0.5 |
Onchocerca volvulus | 0.0894 | 1 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0894 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.0024 | 0.5 |
Schistosoma mansoni | inhibitor of apoptosis protein | 0.0894 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.0024 | 0.5 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0054 | 0.0198 | 0.0198 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0054 | 0.0198 | 0.0198 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0288 | 0.2929 | 0.2929 |
Loa Loa (eye worm) | hypothetical protein | 0.0894 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0288 | 0.2929 | 0.2929 |
Echinococcus multilocularis | baculoviral IAP repeat containing protein | 0.0894 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0894 | 1 | 1 |
Echinococcus granulosus | baculoviral IAP repeat containing protein | 0.0894 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0039 | 0.0024 | 0.0024 |
Brugia malayi | Inhibitor of Apoptosis domain containing protein | 0.0894 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0198 | 0.0198 |
Echinococcus granulosus | inhibitor of apoptosis protein | 0.0894 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0039 | 0.0024 | 0.0024 |
Schistosoma mansoni | inhibitor of apoptosis (iap) domain family member | 0.0894 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.0024 | 0.5 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0039 | 0.0024 | 0.0024 |
Echinococcus multilocularis | inhibitor of apoptosis protein | 0.0894 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.0024 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (functional) | Antifungal activity against Candida albicans ATCC 10231 at 125 ug/ml after 48 to 72 hrs by broth microdilution method | ChEMBL. | 24361188 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.