Detailed information for compound 1821533

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 163.238 | Formula: C6H13NO2S
  • H donors: 0 H acceptors: 1 LogP: 0.56 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: SC[C@H](C(=O)N(OC)C)C
  • InChi: 1S/C6H13NO2S/c1-5(4-10)6(8)7(2)9-3/h5,10H,4H2,1-3H3/t5-/m1/s1
  • InChiKey: FNIUOMSPHHPZJI-RXMQYKEDSA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Echinococcus granulosus tyrosine protein kinase Srms 0.0506 0.3474 0.3339
Schistosoma mansoni protein kinase 0.0506 0.3474 0.3339
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0506 0.3474 1
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0506 0.3474 0.3339
Trichomonas vaginalis TKL family protein kinase 0.0506 0.3474 1
Entamoeba histolytica protein kinase domain containing protein 0.0506 0.3474 0.3474
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0506 0.3474 1
Trichomonas vaginalis TKL family protein kinase 0.0506 0.3474 1
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0506 0.3474 1
Trichomonas vaginalis TKL family protein kinase 0.0506 0.3474 1
Loa Loa (eye worm) TK/FER protein kinase 0.0506 0.3474 1
Entamoeba histolytica protein kinase, putative 0.0506 0.3474 0.3474
Trichomonas vaginalis TKL family protein kinase 0.0506 0.3474 1
Trichomonas vaginalis TKL family protein kinase 0.0506 0.3474 1
Schistosoma mansoni tyrosine kinase 0.0506 0.3474 0.3339
Brugia malayi Protein kinase domain containing protein 0.0506 0.3474 1
Echinococcus multilocularis epidermal growth factor receptor 0.0506 0.3474 0.3339
Entamoeba histolytica protein kinase domain containing protein 0.0506 0.3474 0.3474
Echinococcus granulosus tyrosine protein kinase Blk 0.0506 0.3474 0.3339
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0506 0.3474 0.3339
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0506 0.3474 0.3339
Entamoeba histolytica hypothetical protein 0.0506 0.3474 0.3474
Loa Loa (eye worm) hypothetical protein 0.0506 0.3474 1
Toxoplasma gondii protein kinase domain-containing protein 0.0506 0.3474 0.9757
Schistosoma mansoni tyrosine kinase 0.0506 0.3474 0.3339
Echinococcus multilocularis activin receptor type 0.0518 0.3555 0.3422
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0506 0.3474 0.3339
Brugia malayi Protein kinase domain containing protein 0.0506 0.3474 1
Trichomonas vaginalis conserved hypothetical protein 0.0506 0.3474 1
Mycobacterium ulcerans esterase/lipase LipP 0.0041 0.0203 0.5
Entamoeba histolytica tyrosine kinase, putative 0.0506 0.3474 0.3474
Schistosoma mansoni tyrosine kinase 0.0506 0.3474 0.3339
Loa Loa (eye worm) TK/FER protein kinase 0.0506 0.3474 1
Onchocerca volvulus 0.0506 0.3474 1
Schistosoma mansoni tyrosine kinase 0.0506 0.3474 0.3339
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0506 0.3474 1
Trichomonas vaginalis TKL family protein kinase 0.0506 0.3474 1
Schistosoma mansoni protein kinase 0.0506 0.3474 0.3339
Mycobacterium ulcerans beta-lactamase 0.0041 0.0203 0.5
Brugia malayi protein-tyrosine kinase 0.0506 0.3474 1
Echinococcus granulosus activin receptor type 0.0518 0.3555 0.3422
Echinococcus granulosus retinal guanylyl cyclase 2 0.0506 0.3474 0.3339
Echinococcus granulosus tyrosine protein kinase csk 0.0506 0.3474 0.3339
Schistosoma mansoni protein kinase 0.0506 0.3474 0.3339
Onchocerca volvulus 0.0506 0.3474 1
Echinococcus granulosus tyrosine protein kinase Fyn 0.0506 0.3474 0.3339
Trypanosoma cruzi protein kinase, putative 0.0506 0.3474 0.977
Entamoeba histolytica tyrosine kinase, putative 0.0506 0.3474 0.3474
Echinococcus multilocularis tyrosine protein kinase csk 0.0506 0.3474 0.3339
Entamoeba histolytica tyrosine kinase, putative 0.0506 0.3474 0.3474
Loa Loa (eye worm) TK/ALK protein kinase 0.0506 0.3474 1
Entamoeba histolytica protein kinase, putative 0.0506 0.3474 0.3474
Schistosoma mansoni tyrosine kinase 0.0506 0.3474 0.3339
Schistosoma mansoni tyrosine kinase 0.0506 0.3474 0.3339
Entamoeba histolytica hypothetical protein 0.0506 0.3474 0.3474
Trichomonas vaginalis TKL family protein kinase 0.0506 0.3474 1
Entamoeba histolytica protein kinase domain containing protein 0.0506 0.3474 0.3474
Entamoeba histolytica protein kinase, putative 0.1435 1 1
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0518 0.3555 1
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0506 0.3474 0.3339
Onchocerca volvulus 0.0506 0.3474 1
Loa Loa (eye worm) TK/FER protein kinase 0.0506 0.3474 1
Trichomonas vaginalis conserved hypothetical protein 0.0506 0.3474 1
Entamoeba histolytica tyrosine kinase, putative 0.0506 0.3474 0.3474
Entamoeba histolytica tyrosine kinase, putative 0.0506 0.3474 0.3474
Onchocerca volvulus 0.0506 0.3474 1
Echinococcus multilocularis ephrin type A receptor 4 A 0.0506 0.3474 0.3339
Entamoeba histolytica protein kinase, putative 0.0506 0.3474 0.3474
Schistosoma mansoni protein kinase 0.0506 0.3474 0.3339
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0506 0.3474 0.3339
Schistosoma mansoni tyrosine kinase 0.0506 0.3474 0.3339
Schistosoma mansoni tyrosine kinase 0.0506 0.3474 0.3339
Echinococcus granulosus integrin linked protein kinase 0.0506 0.3474 0.3339
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0506 0.3474 0.3339
Loa Loa (eye worm) TK/FER protein kinase 0.0506 0.3474 1
Echinococcus granulosus activated cdc42 kinase 1 0.0506 0.3474 0.3339
Entamoeba histolytica protein kinase, putative 0.0506 0.3474 0.3474
Loa Loa (eye worm) TK/INSR protein kinase 0.0506 0.3474 1
Trichomonas vaginalis TKL family protein kinase 0.0506 0.3474 1
Schistosoma mansoni tyrosine kinase 0.0506 0.3474 0.3339
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.0203 0.057
Brugia malayi Protein kinase domain containing protein 0.0506 0.3474 1
Entamoeba histolytica tyrosine kinase, putative 0.0506 0.3474 0.3474
Onchocerca volvulus Tyrosine kinase homolog 0.0506 0.3474 1
Brugia malayi Raf kinase 0.0506 0.3474 1
Entamoeba histolytica protein kinase domain containing protein 0.0506 0.3474 0.3474
Entamoeba histolytica tyrosin kinase, putative 0.0506 0.3474 0.3474
Trypanosoma brucei Flagellum attachment zone protein 20 0.0506 0.3474 0.977
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0506 0.3474 0.3339
Trichomonas vaginalis TKL family protein kinase 0.0506 0.3474 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0506 0.3474 0.3474
Trypanosoma brucei protein kinase, putative 0.0518 0.3555 1
Brugia malayi Protein kinase domain containing protein 0.0506 0.3474 1
Onchocerca volvulus 0.0506 0.3474 1
Entamoeba histolytica hypothetical protein 0.0506 0.3474 0.3474
Schistosoma mansoni protein kinase 0.0518 0.3555 0.3422
Brugia malayi Protein kinase domain containing protein 0.0506 0.3474 1
Echinococcus granulosus tyrosine protein kinase Src64B 0.0506 0.3474 0.3339
Trichomonas vaginalis CAMK family protein kinase 0.0506 0.3474 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0506 0.3474 0.3474
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0506 0.3474 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0506 0.3474 0.3474
Trichomonas vaginalis TKL family protein kinase 0.0506 0.3474 1
Loa Loa (eye worm) hypothetical protein 0.0506 0.3474 1
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0262 0.1756 1
Schistosoma mansoni tyrosine kinase 0.0506 0.3474 0.3339
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0506 0.3474 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0506 0.3474 0.3474
Loa Loa (eye worm) TK/FAK protein kinase 0.0506 0.3474 1
Trichomonas vaginalis TKL family protein kinase 0.0506 0.3474 1
Echinococcus granulosus activated cdc42 kinase 1 0.0506 0.3474 0.3339
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0506 0.3474 0.3339
Entamoeba histolytica protein kinase, putative 0.0506 0.3474 0.3474
Trichomonas vaginalis TKL family protein kinase 0.0506 0.3474 1
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0506 0.3474 0.3339
Trichomonas vaginalis TKL family protein kinase 0.0506 0.3474 1
Brugia malayi Protein kinase domain containing protein 0.0506 0.3474 1
Loa Loa (eye worm) hypothetical protein 0.0506 0.3474 1
Schistosoma mansoni tyrosine kinase 0.0506 0.3474 0.3339
Entamoeba histolytica protein kinase domain containing protein 0.0506 0.3474 0.3474
Loa Loa (eye worm) hypothetical protein 0.0506 0.3474 1
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0506 0.3474 0.3339
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.1434 0.9996 0.9996
Entamoeba histolytica protein kinase domain containing protein 0.0506 0.3474 0.3474
Echinococcus multilocularis tyrosine protein kinase 0.0506 0.3474 0.3339
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0506 0.3474 0.9757
Trichomonas vaginalis TKL family protein kinase 0.0506 0.3474 1
Entamoeba histolytica protein kinase domain containing protein 0.0506 0.3474 0.3474
Trichomonas vaginalis conserved hypothetical protein 0.0506 0.3474 1
Trichomonas vaginalis TKL family protein kinase 0.0506 0.3474 1
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0506 0.3474 0.3339
Loa Loa (eye worm) hypothetical protein 0.0506 0.3474 1
Mycobacterium leprae conserved hypothetical protein 0.0041 0.0203 0.5
Entamoeba histolytica protein kinase, putative 0.0506 0.3474 0.3474
Trichomonas vaginalis conserved hypothetical protein 0.0506 0.3474 1
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0518 0.3555 1
Loa Loa (eye worm) TK/CSK protein kinase 0.0506 0.3474 1
Plasmodium vivax tyrosine kinase-like protein, putative 0.0506 0.3474 1
Loa Loa (eye worm) TK protein kinase 0.0506 0.3474 1
Echinococcus granulosus tyrosine kinase 0.0506 0.3474 0.3339
Echinococcus multilocularis receptor type guanylyl cyclase 0.0506 0.3474 0.3339
Loa Loa (eye worm) hypothetical protein 0.0506 0.3474 1
Schistosoma mansoni tyrosine kinase 0.0506 0.3474 0.3339
Brugia malayi Protein kinase domain containing protein 0.0506 0.3474 1
Entamoeba histolytica protein kinase domain containing protein 0.0506 0.3474 0.3474
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0506 0.3474 0.3474
Loa Loa (eye worm) protein kinase domain-containing protein 0.0506 0.3474 1
Trypanosoma cruzi protein kinase, putative 0.0506 0.3474 0.977
Schistosoma mansoni tyrosine kinase 0.0506 0.3474 0.3339
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0506 0.3474 0.3339
Trichomonas vaginalis TKL family protein kinase 0.0506 0.3474 1
Onchocerca volvulus 0.0506 0.3474 1
Echinococcus multilocularis tyrosine protein kinase Abl 0.0506 0.3474 0.3339
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0506 0.3474 0.3474
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0506 0.3474 0.3339
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0506 0.3474 0.3339
Onchocerca volvulus 0.0506 0.3474 1
Trichomonas vaginalis protein tyrosine kinase, putative 0.0506 0.3474 1
Mycobacterium ulcerans hypothetical protein 0.0041 0.0203 0.5
Entamoeba histolytica protein kinase, putative 0.0506 0.3474 0.3474
Entamoeba histolytica protein kinase, putative 0.0506 0.3474 0.3474
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0506 0.3474 1
Brugia malayi Tyrosine-protein kinase abl-1 0.0506 0.3474 1
Echinococcus multilocularis tyrosine protein kinase pr2 0.0506 0.3474 0.3339
Schistosoma mansoni serine/threonine protein kinase 0.0506 0.3474 0.3339
Schistosoma mansoni tyrosine kinase 0.0506 0.3474 0.3339
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0506 0.3474 0.3339
Loa Loa (eye worm) TK/DDR protein kinase 0.0506 0.3474 1
Loa Loa (eye worm) TK protein kinase 0.0506 0.3474 1
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0506 0.3474 0.3339
Brugia malayi Protein kinase domain containing protein 0.0506 0.3474 1
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0506 0.3474 0.3339
Echinococcus granulosus fibroblast growth factor receptor 4 0.0506 0.3474 0.3339
Echinococcus multilocularis integrin linked protein kinase 0.0506 0.3474 0.3339
Brugia malayi hypothetical protein 0.0506 0.3474 1
Loa Loa (eye worm) TK protein kinase 0.0506 0.3474 1
Schistosoma mansoni tyrosine kinase 0.0506 0.3474 0.3339
Brugia malayi Protein kinase domain containing protein 0.0506 0.3474 1
Entamoeba histolytica tyrosine kinase, putative 0.0506 0.3474 0.3474
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0506 0.3474 0.3339
Loa Loa (eye worm) hypothetical protein 0.0506 0.3474 1
Schistosoma mansoni tyrosine kinase 0.0506 0.3474 0.3339
Brugia malayi SH2 domain containing protein 0.0506 0.3474 1
Loa Loa (eye worm) TK/FER protein kinase 0.0506 0.3474 1
Schistosoma mansoni protein kinase 0.0506 0.3474 0.3339
Schistosoma mansoni tyrosine kinase 0.0506 0.3474 0.3339
Entamoeba histolytica tyrosin kinase, putative 0.0506 0.3474 0.3474
Loa Loa (eye worm) RGC/RGC protein kinase 0.0506 0.3474 1
Entamoeba histolytica protein kinase, putative 0.0506 0.3474 0.3474
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0506 0.3474 0.3339
Trichomonas vaginalis conserved hypothetical protein 0.0506 0.3474 1
Plasmodium vivax protein kinase, putative 0.0506 0.3474 1
Entamoeba histolytica hypothetical protein 0.0506 0.3474 0.3474
Entamoeba histolytica hypothetical protein 0.0506 0.3474 0.3474
Schistosoma mansoni tyrosine kinase 0.0506 0.3474 0.3339
Loa Loa (eye worm) TK/FER protein kinase 0.0506 0.3474 1
Brugia malayi SH2 domain containing protein 0.0506 0.3474 1
Entamoeba histolytica tyrosine kinase, putative 0.0506 0.3474 0.3474
Trichomonas vaginalis TKL family protein kinase 0.0506 0.3474 1
Brugia malayi Protein kinase domain containing protein 0.0506 0.3474 1
Entamoeba histolytica protein kinase, putative 0.1435 1 1
Trichomonas vaginalis TKL family protein kinase 0.0506 0.3474 1
Echinococcus multilocularis FL cytokine receptor 0.0506 0.3474 0.3339
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0506 0.3474 0.3339
Echinococcus multilocularis tyrosine protein kinase shark 0.0506 0.3474 0.3339
Mycobacterium ulcerans lipase LipD 0.0041 0.0203 0.5
Loa Loa (eye worm) RGC/RGC protein kinase 0.0506 0.3474 1
Onchocerca volvulus 0.0506 0.3474 1
Entamoeba histolytica hypothetical protein 0.0506 0.3474 0.3474
Schistosoma mansoni serine/threonine protein kinase 0.1435 1 1
Entamoeba histolytica receptor protein kinase, putative 0.0506 0.3474 0.3474
Echinococcus granulosus epidermal growth factor receptor 0.0506 0.3474 0.3339
Brugia malayi Immunoglobulin I-set domain containing protein 0.0506 0.3474 1
Entamoeba histolytica protein kinase domain containing protein 0.0506 0.3474 0.3474
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0506 0.3474 0.3474
Echinococcus multilocularis activated cdc42 kinase 1 0.0506 0.3474 0.3339
Plasmodium falciparum protein kinase, putative 0.0518 0.3555 1
Entamoeba histolytica protein kinase domain containing protein 0.0506 0.3474 0.3474
Trichomonas vaginalis TKL family protein kinase 0.0506 0.3474 1
Echinococcus granulosus protein tyrosine kinase 0.0506 0.3474 0.3339
Trypanosoma brucei hypothetical protein, conserved 0.0041 0.0203 0.057
Echinococcus multilocularis tyrosine protein kinase Blk 0.0506 0.3474 0.3339
Echinococcus multilocularis natriuretic peptide receptor 1 0.0506 0.3474 0.3339
Brugia malayi SRC-1 0.0506 0.3474 1
Trichomonas vaginalis TKL family protein kinase 0.0506 0.3474 1
Trichomonas vaginalis TKL family protein kinase 0.0506 0.3474 1
Trichomonas vaginalis TKL family protein kinase 0.0506 0.3474 1
Schistosoma mansoni tyrosine kinase 0.0506 0.3474 0.3339
Brugia malayi Protein kinase domain containing protein 0.0506 0.3474 1
Trichomonas vaginalis TKL family protein kinase 0.0506 0.3474 1
Schistosoma mansoni ephrin receptor 0.0506 0.3474 0.3339
Brugia malayi Tyrosine-protein kinase PR2 0.0506 0.3474 1
Trichomonas vaginalis TKL family protein kinase 0.0506 0.3474 1
Trichomonas vaginalis TKL family protein kinase 0.0506 0.3474 1
Entamoeba histolytica ankyrin repeat protein 0.0506 0.3474 0.3474
Echinococcus granulosus tyrosine protein kinase shark 0.0506 0.3474 0.3339
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0506 0.3474 0.3339
Brugia malayi Protein kinase domain containing protein 0.0506 0.3474 1
Echinococcus multilocularis kinase suppressor of Ras 1 0.0506 0.3474 0.3339
Entamoeba histolytica protein kinase domain containing protein 0.0506 0.3474 0.3474
Onchocerca volvulus 0.0506 0.3474 1
Brugia malayi Furin-like cysteine rich region family protein 0.0506 0.3474 1
Echinococcus multilocularis protein kinase 0.0506 0.3474 0.3339
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0506 0.3474 1
Echinococcus granulosus tyrosine kinase 0.0506 0.3474 0.3339
Schistosoma mansoni tyrosine kinase 0.0506 0.3474 0.3339
Schistosoma mansoni protein kinase 0.0506 0.3474 0.3339
Brugia malayi Protein kinase domain containing protein 0.0506 0.3474 1
Loa Loa (eye worm) TK/ABL protein kinase 0.0506 0.3474 1
Entamoeba histolytica protein kinase, putative 0.0506 0.3474 0.3474
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0506 0.3474 0.3339
Trichomonas vaginalis TKL family protein kinase 0.0506 0.3474 1
Entamoeba histolytica protein kinase domain containing protein 0.0506 0.3474 0.3474
Echinococcus granulosus c src tyrosine kinase 0.0506 0.3474 0.3339
Loa Loa (eye worm) TK/FER protein kinase 0.0506 0.3474 1
Schistosoma mansoni ephrin receptor 0.0506 0.3474 0.3339
Trichomonas vaginalis TKL family protein kinase 0.0506 0.3474 1
Entamoeba histolytica protein kinase, putative 0.0506 0.3474 0.3474
Echinococcus multilocularis heat shock protein 70 0.0506 0.3474 0.3339
Entamoeba histolytica hypothetical protein 0.0506 0.3474 0.3474
Onchocerca volvulus 0.0506 0.3474 1
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0506 0.3474 0.3339
Echinococcus granulosus tyrosine protein kinase Src42A 0.0506 0.3474 0.3339
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0041 0.0203 0.5
Entamoeba histolytica protein kinase domain containing protein 0.0506 0.3474 0.3474
Brugia malayi Protein kinase domain containing protein 0.0506 0.3474 1
Trichomonas vaginalis TKL family protein kinase 0.0506 0.3474 1
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0506 0.3474 0.3339
Entamoeba histolytica hypothetical protein 0.0506 0.3474 0.3474
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0506 0.3474 1
Loa Loa (eye worm) TK/RYK protein kinase 0.0506 0.3474 1
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0506 0.3474 0.3339
Loa Loa (eye worm) TK protein kinase 0.0506 0.3474 1
Echinococcus granulosus tyrosine protein kinase HCK 0.0506 0.3474 0.3339
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0506 0.3474 0.3339
Loa Loa (eye worm) TK/FER protein kinase 0.0506 0.3474 1
Loa Loa (eye worm) TK/FER protein kinase 0.0506 0.3474 1
Trichomonas vaginalis TKL family protein kinase 0.0506 0.3474 1
Trichomonas vaginalis TKL family protein kinase 0.0506 0.3474 1
Trichomonas vaginalis TKL family protein kinase 0.0506 0.3474 1
Onchocerca volvulus 0.0506 0.3474 1
Trichomonas vaginalis TKL family protein kinase 0.0506 0.3474 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0506 0.3474 0.3474
Echinococcus granulosus retinal guanylyl cyclase 2 0.0506 0.3474 0.3339
Loa Loa (eye worm) hypothetical protein 0.0506 0.3474 1
Trichomonas vaginalis TKL family protein kinase 0.0506 0.3474 1
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0506 0.3474 1
Entamoeba histolytica tyrosine kinase, putative 0.0506 0.3474 0.3474
Brugia malayi Protein kinase domain containing protein 0.0506 0.3474 1
Trichomonas vaginalis TKL family protein kinase 0.0506 0.3474 1
Entamoeba histolytica tyrosine kinase, putative 0.0506 0.3474 0.3474
Entamoeba histolytica protein kinase, putative 0.0506 0.3474 0.3474
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0518 0.3555 1
Trichomonas vaginalis TKL family protein kinase 0.0506 0.3474 1
Onchocerca volvulus 0.0506 0.3474 1
Schistosoma mansoni tyrosine kinase 0.0506 0.3474 0.3339
Brugia malayi Protein kinase domain containing protein 0.0506 0.3474 1
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0506 0.3474 0.3339
Brugia malayi Protein kinase domain containing protein 0.0506 0.3474 1
Brugia malayi ephrin receptor 1 precursor 0.0506 0.3474 1
Schistosoma mansoni tyrosine protein kinase 0.0506 0.3474 0.3339
Trichomonas vaginalis TKL family protein kinase 0.0506 0.3474 1
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0506 0.3474 0.3339
Brugia malayi hypothetical protein 0.0506 0.3474 1
Trichomonas vaginalis TKL family protein kinase 0.0506 0.3474 1
Loa Loa (eye worm) hypothetical protein 0.0506 0.3474 1
Trichomonas vaginalis TKL family protein kinase 0.0506 0.3474 1
Trichomonas vaginalis TKL family protein kinase 0.0506 0.3474 1
Echinococcus granulosus tyrosine protein kinase pr2 0.0506 0.3474 0.3339
Entamoeba histolytica tyrosine kinase, putative 0.0506 0.3474 0.3474
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0506 0.3474 0.3339
Brugia malayi C-terminal src kinase protein 1 0.0506 0.3474 1
Trichomonas vaginalis TKL family protein kinase 0.0506 0.3474 1
Loa Loa (eye worm) TK/FER protein kinase 0.0506 0.3474 1
Plasmodium vivax tyrosine kinase-like protein, putative 0.0506 0.3474 1
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0506 0.3474 1
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0506 0.3474 0.3339
Echinococcus granulosus tyrosine kinase 0.0506 0.3474 0.3339
Brugia malayi Protein kinase domain containing protein 0.0506 0.3474 1
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0506 0.3474 0.3339
Loa Loa (eye worm) TK/ACK protein kinase 0.0506 0.3474 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0506 0.3474 0.3474
Entamoeba histolytica hypothetical protein 0.0506 0.3474 0.3474
Entamoeba histolytica protein kinase, putative 0.0506 0.3474 0.3474
Entamoeba histolytica protein kinase, putative 0.0506 0.3474 0.3474
Schistosoma mansoni tyrosine kinase 0.0506 0.3474 0.3339
Trichomonas vaginalis TKL family protein kinase 0.0506 0.3474 1
Schistosoma mansoni serine/threonine protein kinase 0.0506 0.3474 0.3339
Echinococcus granulosus tyrosine protein kinase csk 0.0506 0.3474 0.3339
Loa Loa (eye worm) TK protein kinase 0.0506 0.3474 1
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0506 0.3474 0.9757
Trichomonas vaginalis TKL family protein kinase 0.0506 0.3474 1
Loa Loa (eye worm) RGC/RGC protein kinase 0.0506 0.3474 1
Schistosoma mansoni protein tyrosine kinase 0.0506 0.3474 0.3339
Echinococcus multilocularis protein tyrosine kinase 0.0506 0.3474 0.3339
Entamoeba histolytica protein kinase domain containing protein 0.0506 0.3474 0.3474
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0506 0.3474 0.3339
Loa Loa (eye worm) hypothetical protein 0.0506 0.3474 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0506 0.3474 0.3474
Loa Loa (eye worm) TK/ROR protein kinase 0.0506 0.3474 1
Entamoeba histolytica ankyrin repeat protein 0.0506 0.3474 0.3474
Entamoeba histolytica hypothetical protein, conserved 0.0506 0.3474 0.3474
Schistosoma mansoni tyrosine kinase 0.0506 0.3474 0.3339
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0506 0.3474 0.3339
Echinococcus granulosus tyrosine protein kinase csk 0.0506 0.3474 0.3339
Echinococcus granulosus tyrosine protein kinase Fyn 0.0506 0.3474 0.3339
Entamoeba histolytica protein kinase, putative 0.0506 0.3474 0.3474
Echinococcus granulosus ephrin type A receptor 4 A 0.0506 0.3474 0.3339
Loa Loa (eye worm) TK/FER protein kinase 0.0506 0.3474 1
Entamoeba histolytica serine/threonine kinase, putative 0.0506 0.3474 0.3474
Entamoeba histolytica serine/threonine kinase, putative 0.0506 0.3474 0.3474
Loa Loa (eye worm) TK protein kinase 0.0506 0.3474 1
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0506 0.3474 1
Entamoeba histolytica tyrosine kinase, putative 0.0506 0.3474 0.3474
Echinococcus granulosus protein kinase 0.0506 0.3474 0.3339
Trichomonas vaginalis TKL family protein kinase 0.0506 0.3474 1
Entamoeba histolytica protein kinase, putative 0.0506 0.3474 0.3474
Trichomonas vaginalis conserved hypothetical protein 0.0506 0.3474 1
Brugia malayi Protein kinase domain containing protein 0.0506 0.3474 1
Brugia malayi Protein kinase domain containing protein 0.0506 0.3474 1
Loa Loa (eye worm) TK/FER protein kinase 0.0506 0.3474 1
Loa Loa (eye worm) TK/FER protein kinase 0.0506 0.3474 1
Entamoeba histolytica tyrosine kinase, putative 0.0506 0.3474 0.3474
Schistosoma mansoni tyrosine kinase 0.0506 0.3474 0.3339
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0506 0.3474 0.3339
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0506 0.3474 1
Brugia malayi Protein kinase domain containing protein 0.0506 0.3474 1
Schistosoma mansoni serine/threonine RGC 0.0506 0.3474 0.3339
Echinococcus multilocularis tyrosine protein kinase csk 0.0506 0.3474 0.3339
Loa Loa (eye worm) RGC/RGC protein kinase 0.0506 0.3474 1
Loa Loa (eye worm) hypothetical protein 0.0506 0.3474 1
Entamoeba histolytica tyrosine kinase, putative 0.0506 0.3474 0.3474
Echinococcus granulosus tyrosine protein kinase Fyn 0.0506 0.3474 0.3339
Trichomonas vaginalis TKL family protein kinase 0.0506 0.3474 1
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0506 0.3474 0.3339
Entamoeba histolytica protein kinase domain containing protein 0.0518 0.3555 0.3555
Trichomonas vaginalis AGC family protein kinase 0.0506 0.3474 1
Trichomonas vaginalis protein kinase atn1, putative 0.0506 0.3474 1
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0506 0.3474 0.3339
Entamoeba histolytica serine/threonine kinase, putative 0.0506 0.3474 0.3474
Mycobacterium leprae Probable lipase LipE 0.0041 0.0203 0.5
Echinococcus multilocularis epidermal growth factor receptor 0.0506 0.3474 0.3339
Schistosoma mansoni tyrosine kinase 0.0506 0.3474 0.3339
Entamoeba histolytica protein kinase domain containing protein 0.0506 0.3474 0.3474
Trichomonas vaginalis TKL family protein kinase 0.0506 0.3474 1
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0506 0.3474 0.3339
Loa Loa (eye worm) hypothetical protein 0.0506 0.3474 1
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0506 0.3474 1
Echinococcus multilocularis tyrosine protein kinase csk 0.0506 0.3474 0.3339
Entamoeba histolytica protein kinase domain containing protein 0.0506 0.3474 0.3474
Brugia malayi integrin-linked kinase 0.0506 0.3474 1
Entamoeba histolytica tyrosin kinase, putative 0.0506 0.3474 0.3474
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0506 0.3474 0.3339
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0506 0.3474 0.3339
Leishmania major hypothetical protein, conserved 0.0506 0.3474 0.977
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0506 0.3474 1
Trypanosoma brucei Pseudokinase, putative 0.0506 0.3474 0.977
Entamoeba histolytica tyrosine kinase, putative 0.0506 0.3474 0.3474
Trichomonas vaginalis TKL family protein kinase 0.0506 0.3474 1
Loa Loa (eye worm) serine/threonine protein kinase 0.0506 0.3474 1
Trichomonas vaginalis TKL family protein kinase 0.0506 0.3474 1
Giardia lamblia Kinase, NEK 0.0506 0.3474 0.5
Schistosoma mansoni serine/threonine protein kinase 0.0506 0.3474 0.3339
Trichomonas vaginalis TK family protein kinase 0.0506 0.3474 1
Schistosoma mansoni tyrosine kinase 0.0506 0.3474 0.3339
Schistosoma mansoni tyrosine kinase 0.0506 0.3474 0.3339
Giardia lamblia Protein 21.1 0.0506 0.3474 0.5
Trichomonas vaginalis TKL family protein kinase 0.0506 0.3474 1
Loa Loa (eye worm) TK/EPH protein kinase 0.0506 0.3474 1
Echinococcus granulosus epidermal growth factor receptor 0.0506 0.3474 0.3339
Brugia malayi Protein kinase domain containing protein 0.0506 0.3474 1
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0506 0.3474 0.3339
Echinococcus multilocularis tyrosine protein kinase csk 0.0506 0.3474 0.3339
Entamoeba histolytica protein kinase, putative 0.0506 0.3474 0.3474
Brugia malayi Protein kinase domain containing protein 0.0506 0.3474 1
Onchocerca volvulus 0.0506 0.3474 1
Schistosoma mansoni hypothetical protein 0.0506 0.3474 0.3339
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0948 0.6582 0.6511
Entamoeba histolytica protein kinase domain containing protein 0.0506 0.3474 0.3474
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0506 0.3474 0.3474
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0506 0.3474 1
Brugia malayi hypothetical protein 0.0506 0.3474 1
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0506 0.3474 0.3474
Echinococcus multilocularis transfer RNA-Thr 0.0506 0.3474 0.3339
Toxoplasma gondii protein kinase 0.0506 0.3474 0.9757
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0506 0.3474 1
Loa Loa (eye worm) TK/EGFR protein kinase 0.0506 0.3474 1
Echinococcus granulosus tyrosine protein kinase Lyn 0.0518 0.3555 0.3422
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0518 0.3555 1
Brugia malayi bone morphogenetic protein type 1 receptor 0.0506 0.3474 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0506 0.3474 0.3474
Echinococcus granulosus natriuretic peptide receptor 1 0.0506 0.3474 0.3339
Trichomonas vaginalis TKL family protein kinase 0.0506 0.3474 1
Brugia malayi Protein kinase domain containing protein 0.0506 0.3474 1
Brugia malayi Protein kinase domain containing protein 0.0506 0.3474 1
Entamoeba histolytica protein kinase domain containing protein 0.0506 0.3474 0.3474
Trichomonas vaginalis STE family protein kinase 0.0506 0.3474 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0506 0.3474 0.3474
Echinococcus multilocularis tyrosine kinase 0.0506 0.3474 0.3339
Echinococcus multilocularis protein kinase 0.0506 0.3474 0.3339
Loa Loa (eye worm) hypothetical protein 0.0506 0.3474 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0506 0.3474 1
Loa Loa (eye worm) TK protein kinase 0.0506 0.3474 1
Entamoeba histolytica serine/threonine kinase, putative 0.0506 0.3474 0.3474
Schistosoma mansoni tyrosine kinase 0.0506 0.3474 0.3339
Entamoeba histolytica tyrosine kinase, putative 0.0506 0.3474 0.3474
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0506 0.3474 1
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0506 0.3474 0.3339
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0506 0.3474 0.3339
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.1434 0.9996 0.9996
Echinococcus multilocularis tyrosine protein kinase HCK 0.0506 0.3474 0.3339
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0506 0.3474 0.3339
Echinococcus granulosus retinal guanylyl cyclase 2 0.0506 0.3474 0.3339
Loa Loa (eye worm) TK/FER protein kinase 0.0506 0.3474 1
Schistosoma mansoni serine/threonine protein kinase 0.0506 0.3474 0.3339
Entamoeba histolytica receptor protein kinase, putative 0.0506 0.3474 0.3474
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0506 0.3474 0.3474
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0518 0.3555 0.3422
Schistosoma mansoni protein kinase 0.0518 0.3555 0.3422
Trichomonas vaginalis TKL family protein kinase 0.0506 0.3474 1
Schistosoma mansoni tyrosine kinase 0.0506 0.3474 0.3339
Loa Loa (eye worm) TK protein kinase 0.0506 0.3474 1
Trichomonas vaginalis TKL family protein kinase 0.0506 0.3474 1
Entamoeba histolytica serine/threonine kinase, putative 0.0506 0.3474 0.3474
Entamoeba histolytica serine/threonine kinase, putative 0.0506 0.3474 0.3474
Entamoeba histolytica protein kinase, putative 0.0506 0.3474 0.3474
Brugia malayi Receptor family ligand binding region containing protein 0.0506 0.3474 1
Trichomonas vaginalis TKL family protein kinase 0.0506 0.3474 1
Trichomonas vaginalis TKL family protein kinase 0.0506 0.3474 1
Entamoeba histolytica tyrosin kinase, putative 0.0506 0.3474 0.3474
Entamoeba histolytica protein kinase domain containing protein 0.0506 0.3474 0.3474
Giardia lamblia Kinase, NEK 0.0506 0.3474 0.5
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0506 0.3474 0.3474
Entamoeba histolytica hypothetical protein 0.0506 0.3474 0.3474
Loa Loa (eye worm) TK protein kinase 0.0506 0.3474 1
Schistosoma mansoni protein kinase 0.0518 0.3555 0.3422
Echinococcus multilocularis insulin receptor 0.0506 0.3474 0.3339
Entamoeba histolytica cysteine surface protein, putative 0.0506 0.3474 0.3474
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0506 0.3474 0.977
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0506 0.3474 0.3339
Brugia malayi Protein kinase domain containing protein 0.0506 0.3474 1
Echinococcus multilocularis protein KINase family member (kin 25) 0.0506 0.3474 0.3339
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0506 0.3474 1
Echinococcus multilocularis tyrosine kinase 0.0506 0.3474 0.3339
Loa Loa (eye worm) SRC-1 0.0506 0.3474 1
Trichomonas vaginalis TKL family protein kinase 0.0506 0.3474 1
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0506 0.3474 0.3339
Echinococcus multilocularis raf serine:threonine protein kinase 0.0506 0.3474 0.3339
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0518 0.3555 0.3422
Onchocerca volvulus 0.0506 0.3474 1
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.0203 0.057
Brugia malayi Protein kinase domain containing protein 0.0506 0.3474 1
Echinococcus granulosus tyrosine protein kinase ABL1 0.0506 0.3474 0.3339
Entamoeba histolytica protein kinase, putative 0.0506 0.3474 0.3474
Schistosoma mansoni tyrosine kinase 0.0506 0.3474 0.3339
Entamoeba histolytica hypothetical protein 0.0506 0.3474 0.3474
Schistosoma mansoni tyrosine kinase 0.0506 0.3474 0.3339
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0506 0.3474 0.3339
Trichomonas vaginalis conserved hypothetical protein 0.0506 0.3474 1
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.1435 1 1
Loa Loa (eye worm) TK/Met protein kinase 0.0506 0.3474 1
Onchocerca volvulus 0.0506 0.3474 1
Brugia malayi Guanylyl cyclase protein 23 0.0506 0.3474 1
Toxoplasma gondii STE kinase 0.0506 0.3474 0.9757
Loa Loa (eye worm) TK protein kinase 0.0506 0.3474 1
Brugia malayi Protein kinase domain containing protein 0.0506 0.3474 1
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0506 0.3474 1
Trichomonas vaginalis TKL family protein kinase 0.0506 0.3474 1
Brugia malayi Protein kinase domain containing protein 0.0506 0.3474 1
Schistosoma mansoni protein kinase 0.0506 0.3474 0.3339
Trichomonas vaginalis TKL family protein kinase 0.0506 0.3474 1
Trichomonas vaginalis TKL family protein kinase 0.0506 0.3474 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0506 0.3474 0.3474
Trichomonas vaginalis TKL family protein kinase 0.0506 0.3474 1
Entamoeba histolytica protein kinase domain containing protein 0.0506 0.3474 0.3474
Trichomonas vaginalis TKL family protein kinase 0.0506 0.3474 1
Loa Loa (eye worm) TK/FER protein kinase 0.0506 0.3474 1
Loa Loa (eye worm) TK/FER protein kinase 0.0506 0.3474 1
Loa Loa (eye worm) TK/FER protein kinase 0.0506 0.3474 1
Echinococcus granulosus receptor type guanylyl cyclase 0.0506 0.3474 0.3339
Giardia lamblia Kinase 0.0506 0.3474 0.5
Entamoeba histolytica tyrosine kinase, putative 0.0506 0.3474 0.3474
Echinococcus granulosus kinase suppressor of Ras 1 0.0506 0.3474 0.3339
Entamoeba histolytica protein kinase domain containing protein 0.0506 0.3474 0.3474
Schistosoma mansoni protein kinase 0.0506 0.3474 0.3339
Echinococcus granulosus insulin receptor 0.0506 0.3474 0.3339
Leishmania major hypothetical protein, conserved 0.0041 0.0203 0.057
Trichomonas vaginalis TKL family protein kinase 0.0506 0.3474 1
Echinococcus multilocularis tyrosine protein kinase Srms 0.0506 0.3474 0.3339
Echinococcus granulosus raf serine:threonine protein kinase 0.0506 0.3474 0.3339
Trichomonas vaginalis TKL family protein kinase 0.0506 0.3474 1
Trichomonas vaginalis TKL family protein kinase 0.0506 0.3474 1
Trichomonas vaginalis TKL family protein kinase 0.0506 0.3474 1
Brugia malayi Protein kinase domain containing protein 0.0506 0.3474 1
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0506 0.3474 0.3339
Echinococcus multilocularis c src tyrosine kinase 0.0506 0.3474 0.3339
Leishmania major protein kinase, putative 0.0506 0.3474 0.977
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0506 0.3474 0.3339
Trichomonas vaginalis TKL family protein kinase 0.0506 0.3474 1
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0506 0.3474 0.3339
Leishmania major protein kinase, putative 0.0518 0.3555 1
Trichomonas vaginalis TKL family protein kinase 0.0506 0.3474 1
Trichomonas vaginalis TKL family protein kinase 0.0506 0.3474 1
Echinococcus granulosus tyrosine protein kinase 0.0506 0.3474 0.3339

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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