Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | disulfide oxidoreductase | 0.0067 | 0.0727 | 0.0727 |
Trichomonas vaginalis | glutamate synthase, putative | 0.0067 | 0.0727 | 0.2085 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0254 | 0.3327 | 0.3327 |
Trypanosoma brucei | pyridine nucleotide-disulphide oxidoreductase, putative | 0.0067 | 0.0727 | 0.0727 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0254 | 0.3327 | 1 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0057 | 0.0584 | 0.0584 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0067 | 0.0727 | 0.2085 |
Giardia lamblia | Glutamate synthase | 0.0067 | 0.0727 | 0.2085 |
Echinococcus multilocularis | peptidase Clp (S14 family) | 0.0051 | 0.0493 | 0.0493 |
Echinococcus multilocularis | pyridine nucleotide disulfide oxidoreductase | 0.0067 | 0.0727 | 0.0727 |
Leishmania major | hypothetical protein, conserved | 0.0067 | 0.0727 | 0.0727 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0018 | 0.0042 | 0.0042 |
Mycobacterium ulcerans | hypothetical protein | 0.0067 | 0.0727 | 0.2085 |
Schistosoma mansoni | sulfide quinone reductase | 0.0067 | 0.0727 | 0.0727 |
Wolbachia endosymbiont of Brugia malayi | NADPH-dependent glutamate synthase beta chain | 0.0067 | 0.0727 | 0.2085 |
Brugia malayi | NADPH:adrenodoxin oxidoreductase, mitochondrial precursor | 0.0067 | 0.0727 | 0.0727 |
Echinococcus granulosus | NADPH:adrenodoxin oxidoreductase | 0.0067 | 0.0727 | 0.0727 |
Brugia malayi | Thioredoxin reductase | 0.0732 | 1 | 1 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0059 | 0.061 | 0.061 |
Schistosoma mansoni | hypothetical protein | 0.0067 | 0.0727 | 0.0727 |
Trypanosoma cruzi | NADH dehydrogenase, putative | 0.0067 | 0.0727 | 0.0727 |
Mycobacterium leprae | THIOREDOXIN TRXC (TRX) (MPT46) | 0.0067 | 0.0727 | 0.1795 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0027 | 0.0158 | 0.0353 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) | 0.0077 | 0.0863 | 0.2225 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0254 | 0.3327 | 0.3327 |
Treponema pallidum | thioredoxin reductase (trxB) | 0.0067 | 0.0727 | 0.2085 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0077 | 0.0863 | 0.0863 |
Schistosoma mansoni | chaperonin containing t-complex protein 1 beta subunit tcpb | 0.0023 | 0.0115 | 0.0115 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0018 | 0.0042 | 0.0042 |
Plasmodium vivax | glutathione reductase, putative | 0.0732 | 1 | 1 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0254 | 0.3327 | 0.3327 |
Trichomonas vaginalis | dihydrolipoamide dehydrogenase, putative | 0.0067 | 0.0727 | 0.2085 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0254 | 0.3327 | 1 |
Giardia lamblia | Glycerol-3-phosphate dehydrogenase | 0.0067 | 0.0727 | 0.2085 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0732 | 1 | 1 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0059 | 0.061 | 0.061 |
Mycobacterium ulcerans | NADH dehydrogenase | 0.0067 | 0.0727 | 0.2085 |
Echinococcus granulosus | ATP dependent Clp protease proteolytic subunit | 0.0077 | 0.0863 | 0.0863 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0254 | 0.3327 | 1 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0254 | 0.3327 | 0.3327 |
Entamoeba histolytica | T-complex protein 1 beta subunit, putative | 0.0023 | 0.0115 | 0.1068 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0018 | 0.0042 | 0.0042 |
Brugia malayi | glutamate synthase | 0.0067 | 0.0727 | 0.0727 |
Brugia malayi | T-complex protein 1, beta subunit | 0.0023 | 0.0115 | 0.0115 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0057 | 0.0584 | 0.0584 |
Toxoplasma gondii | selenide, water dikinase | 0.0067 | 0.0727 | 0.0727 |
Trypanosoma cruzi | 2,4-dienoyl-coa reductase-like protein, putative | 0.0067 | 0.0727 | 0.0727 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0059 | 0.061 | 0.061 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0254 | 0.3327 | 0.3327 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0077 | 0.0863 | 0.0863 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0254 | 0.3327 | 0.3327 |
Leishmania major | T-complex protein 1, beta subunit, putative | 0.0023 | 0.0115 | 0.0115 |
Entamoeba histolytica | dihydropyrimidine dehydrogenase, putative | 0.0067 | 0.0727 | 1 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0732 | 1 | 1 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) | 0.0051 | 0.0493 | 0.0452 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0254 | 0.3327 | 0.3327 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0059 | 0.061 | 0.057 |
Echinococcus granulosus | glutamate synthase | 0.0067 | 0.0727 | 0.0727 |
Mycobacterium ulcerans | ferredoxin reductase | 0.0067 | 0.0727 | 0.2085 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0254 | 0.3327 | 1 |
Giardia lamblia | TCP-1 chaperonin subunit beta | 0.0023 | 0.0115 | 0.0223 |
Loa Loa (eye worm) | programmed cell death 8 | 0.0067 | 0.0727 | 0.0727 |
Echinococcus multilocularis | apoptosis inducing factor 1 mitochondrial | 0.0067 | 0.0727 | 0.0727 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0254 | 0.3327 | 0.3327 |
Schistosoma mansoni | chaperonin containing t-complex protein 1 beta subunit tcpb | 0.0023 | 0.0115 | 0.0115 |
Trypanosoma cruzi | pyridine nucleotide-disulphide oxidoreductase, putative | 0.0067 | 0.0727 | 0.0727 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0067 | 0.0727 | 0.1795 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0254 | 0.3327 | 1 |
Plasmodium falciparum | T-complex protein 1 subunit beta | 0.0023 | 0.0115 | 0.0115 |
Schistosoma mansoni | chaperonin containing t-complex protein 1 beta subunit tcpb | 0.0023 | 0.0115 | 0.0115 |
Mycobacterium ulcerans | NADPH:adrenodoxin oxidoreductase FprA | 0.0067 | 0.0727 | 0.2085 |
Plasmodium falciparum | ferrodoxin reductase-like protein | 0.0067 | 0.0727 | 0.0727 |
Plasmodium vivax | type II NADH:ubiquinone oxidoreductase, putative | 0.0067 | 0.0727 | 0.0727 |
Mycobacterium ulcerans | glutamate synthase subunit beta | 0.0067 | 0.0727 | 0.2085 |
Echinococcus multilocularis | NADPH:adrenodoxin oxidoreductase | 0.0067 | 0.0727 | 0.0727 |
Brugia malayi | T-complex protein 1, beta subunit | 0.0023 | 0.0115 | 0.0115 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent Clp protease proteolytic subunit | 0.0077 | 0.0863 | 0.25 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0057 | 0.0584 | 0.0584 |
Schistosoma mansoni | peptidase Clp (S14 family) | 0.0077 | 0.0863 | 0.0863 |
Entamoeba histolytica | NAD(FAD)-dependent dehydrogenase, putative | 0.0067 | 0.0727 | 1 |
Giardia lamblia | Thioredoxin reductase | 0.0067 | 0.0727 | 0.2085 |
Trichomonas vaginalis | chaperonin-60kD, ch60, putative | 0.0023 | 0.0115 | 0.0223 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0254 | 0.3327 | 0.3327 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0254 | 0.3327 | 0.3327 |
Mycobacterium tuberculosis | Possible dehydrogenase/reductase | 0.0067 | 0.0727 | 0.0688 |
Mycobacterium ulcerans | thioredoxin reductase TrxB2 | 0.0067 | 0.0727 | 0.2085 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0254 | 0.3327 | 0.3327 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0077 | 0.0863 | 0.25 |
Wolbachia endosymbiont of Brugia malayi | thioredoxin reductase | 0.0067 | 0.0727 | 0.2085 |
Toxoplasma gondii | t-complex protein beta subunit | 0.0023 | 0.0115 | 0.0115 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0059 | 0.061 | 0.061 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0254 | 0.3327 | 0.3327 |
Loa Loa (eye worm) | glutathione reductase | 0.0732 | 1 | 1 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0254 | 0.3327 | 0.3327 |
Leishmania major | 2,4-dienoyl-coa reductase-like protein | 0.0067 | 0.0727 | 0.0727 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0732 | 1 | 1 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0059 | 0.061 | 0.1728 |
Brugia malayi | jmjC domain containing protein | 0.0057 | 0.0584 | 0.0584 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0186 | 0.2387 | 0.2387 |
Leishmania major | hypothetical protein, conserved | 0.0067 | 0.0727 | 0.0727 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0067 | 0.0727 | 0.2085 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0018 | 0.0042 | 0.0042 |
Mycobacterium tuberculosis | Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) | 0.0067 | 0.0727 | 0.0688 |
Mycobacterium leprae | PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) | 0.0067 | 0.0727 | 0.1795 |
Toxoplasma gondii | non-proton pumping type-II NADH dehydrogenase I | 0.0067 | 0.0727 | 0.0727 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0254 | 0.3327 | 0.3327 |
Toxoplasma gondii | pyridine nucleotide-disulfide oxidoreductase domain-containing protein | 0.0067 | 0.0727 | 0.0727 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0254 | 0.3327 | 0.3327 |
Trichomonas vaginalis | glutamate synthase, putative | 0.0067 | 0.0727 | 0.2085 |
Trichomonas vaginalis | chaperonin, putative | 0.0023 | 0.0115 | 0.0223 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase family protein | 0.0067 | 0.0727 | 0.0727 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0057 | 0.0584 | 0.0584 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0254 | 0.3327 | 0.3298 |
Entamoeba histolytica | glutamate synthase beta subunit, putative | 0.0067 | 0.0727 | 1 |
Toxoplasma gondii | exonuclease III APE | 0.0018 | 0.0042 | 0.0042 |
Trypanosoma cruzi | pyridine nucleotide-disulphide oxidoreductase, putative | 0.0067 | 0.0727 | 0.0727 |
Schistosoma mansoni | ap endonuclease | 0.0018 | 0.0042 | 0.0042 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0254 | 0.3327 | 1 |
Plasmodium falciparum | glutathione reductase | 0.0254 | 0.3327 | 0.3327 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) | 0.0051 | 0.0493 | 0.0452 |
Echinococcus granulosus | apoptosis inducing factor 1 mitochondrial | 0.0067 | 0.0727 | 0.0727 |
Mycobacterium ulcerans | dehydrogenase | 0.0067 | 0.0727 | 0.2085 |
Echinococcus multilocularis | dihydropyrimidine dehydrogenase (NADP+) | 0.0067 | 0.0727 | 0.0727 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase family protein | 0.0067 | 0.0727 | 0.0727 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0059 | 0.061 | 0.061 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0018 | 0.0042 | 0.0042 |
Trypanosoma brucei | 2,4-dienoyl-coa reductase-like protein | 0.0067 | 0.0727 | 0.0727 |
Entamoeba histolytica | glutamate synthase beta subunit, putative | 0.0067 | 0.0727 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0067 | 0.0727 | 0.0727 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0018 | 0.0042 | 0.0042 |
Plasmodium falciparum | NAD(P)H-dependent glutamate synthase, putative | 0.0067 | 0.0727 | 0.0727 |
Leishmania major | NADH dehydrogenase, putative | 0.0067 | 0.0727 | 0.0727 |
Echinococcus multilocularis | ATP dependent Clp protease proteolytic subunit | 0.0077 | 0.0863 | 0.0863 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0067 | 0.0727 | 0.2085 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0254 | 0.3327 | 0.3327 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0254 | 0.3327 | 0.3298 |
Echinococcus granulosus | dihydropyrimidine dehydrogenase NADP | 0.0067 | 0.0727 | 0.0727 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0254 | 0.3327 | 0.3327 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0077 | 0.0863 | 0.25 |
Echinococcus granulosus | dihydropyrimidine dehydrogenase NADP | 0.0067 | 0.0727 | 0.0727 |
Echinococcus multilocularis | chaperonin containing TCP1, subunit 2 (beta) | 0.0023 | 0.0115 | 0.0115 |
Entamoeba histolytica | thioredoxin reductase, putative | 0.0067 | 0.0727 | 1 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0057 | 0.0584 | 0.0584 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0732 | 1 | 1 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0018 | 0.0042 | 0.0042 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.0067 | 0.0727 | 0.2085 |
Wolbachia endosymbiont of Brugia malayi | thioredoxin reductase | 0.0067 | 0.0727 | 0.2085 |
Schistosoma mansoni | jumonji domain containing protein | 0.0057 | 0.0584 | 0.0584 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0186 | 0.2387 | 0.2387 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0077 | 0.0863 | 0.0524 |
Trypanosoma brucei | trypanothione reductase | 0.0732 | 1 | 1 |
Toxoplasma gondii | pyridine nucleotide-disulfide oxidoreductase domain-containing protein | 0.0067 | 0.0727 | 0.0727 |
Mycobacterium tuberculosis | Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) | 0.0067 | 0.0727 | 0.0688 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0254 | 0.3327 | 1 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0254 | 0.3327 | 0.3327 |
Echinococcus granulosus | peptidase Clp S14 family | 0.0051 | 0.0493 | 0.0493 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0057 | 0.0584 | 0.0584 |
Mycobacterium ulcerans | NADPH:adrenodoxin oxidoreductase FprB | 0.0067 | 0.0727 | 0.2085 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0254 | 0.3327 | 0.3298 |
Trypanosoma cruzi | T-complex protein 1, beta subunit, putative | 0.0023 | 0.0115 | 0.0115 |
Leishmania major | 2,4-dienoyl-coa reductase fadh1, putative | 0.0067 | 0.0727 | 0.0727 |
Schistosoma mansoni | glutamate synthase | 0.0067 | 0.0727 | 0.0727 |
Toxoplasma gondii | pyridine nucleotide-disulfide oxidoreductase domain-containing protein | 0.0067 | 0.0727 | 0.0727 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0254 | 0.3327 | 1 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0067 | 0.0727 | 0.0688 |
Mycobacterium tuberculosis | NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) | 0.0067 | 0.0727 | 0.0688 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0057 | 0.0584 | 0.0584 |
Onchocerca volvulus | 0.0067 | 0.0727 | 0.5 | |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0254 | 0.3327 | 0.3327 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0254 | 0.3327 | 0.3327 |
Plasmodium falciparum | thioredoxin reductase | 0.0732 | 1 | 1 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0059 | 0.061 | 0.1728 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0067 | 0.0727 | 0.0688 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0254 | 0.3327 | 0.3298 |
Trypanosoma cruzi | 2,4-dienoyl-coa reductase fadh1, putative | 0.0067 | 0.0727 | 0.0727 |
Trichomonas vaginalis | apoptosis inducing factor, putative | 0.0067 | 0.0727 | 0.2085 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.0067 | 0.0727 | 0.2085 |
Toxoplasma gondii | NADH dehydrogenase (NDH2-II) | 0.0067 | 0.0727 | 0.0727 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0018 | 0.0042 | 0.0042 |
Trypanosoma cruzi | NADPH:adrenodoxin oxidoreductase, mitochondrial, putative | 0.0067 | 0.0727 | 0.0727 |
Echinococcus granulosus | chaperonin containing TCP1 subunit 2 beta | 0.0023 | 0.0115 | 0.0115 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0732 | 1 | 1 |
Mycobacterium ulcerans | NADPH:adrenodoxin oxidoreductase FprA | 0.0067 | 0.0727 | 0.2085 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0059 | 0.061 | 0.1728 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0018 | 0.0042 | 0.0042 |
Trypanosoma brucei | T-complex protein 1, beta subunit, putative | 0.0023 | 0.0115 | 0.0115 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0254 | 0.3327 | 0.3327 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0254 | 0.3327 | 0.3327 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0067 | 0.0727 | 0.2085 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0067 | 0.0727 | 0.2085 |
Loa Loa (eye worm) | pyridine nucleotide-disufhide oxidoreductase | 0.0067 | 0.0727 | 0.0727 |
Plasmodium vivax | ferrodoxin reductase, putative | 0.0067 | 0.0727 | 0.0727 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0254 | 0.3327 | 0.3327 |
Loa Loa (eye worm) | T-complex protein 1 | 0.0023 | 0.0115 | 0.0115 |
Brugia malayi | jmjC domain containing protein | 0.0057 | 0.0584 | 0.0584 |
Schistosoma mansoni | ap endonuclease | 0.0018 | 0.0042 | 0.0042 |
Mycobacterium ulcerans | NADH dehydrogenase Ndh1 | 0.0067 | 0.0727 | 0.2085 |
Mycobacterium tuberculosis | Probable reductase | 0.0067 | 0.0727 | 0.0688 |
Trichomonas vaginalis | dihydropyrimidine dehydrogenase, putative | 0.0067 | 0.0727 | 0.2085 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0077 | 0.0863 | 0.25 |
Brugia malayi | Probable ClpP-like protease | 0.0077 | 0.0863 | 0.0863 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0027 | 0.0158 | 0.0158 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0254 | 0.3327 | 0.3327 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0018 | 0.0042 | 0.0042 |
Schistosoma mansoni | glutamate synthase | 0.0067 | 0.0727 | 0.0727 |
Plasmodium falciparum | type II NADH:ubiquinone oxidoreductase | 0.0067 | 0.0727 | 0.0727 |
Mycobacterium ulcerans | NADH dehydrogenase Ndh | 0.0067 | 0.0727 | 0.2085 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0254 | 0.3327 | 0.3327 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0067 | 0.0727 | 0.0727 |
Plasmodium vivax | NAD(P)H-dependent glutamate synthase, putative | 0.0067 | 0.0727 | 0.0727 |
Trypanosoma brucei | pyridine nucleotide-disulphide oxidoreductase, putative | 0.0067 | 0.0727 | 0.0727 |
Mycobacterium tuberculosis | Probable thioredoxin reductase TrxB2 (TRXR) (TR) | 0.0067 | 0.0727 | 0.0688 |
Mycobacterium tuberculosis | Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate | 0.0067 | 0.0727 | 0.0688 |
Treponema pallidum | oxidoreductase | 0.0067 | 0.0727 | 0.2085 |
Trypanosoma brucei | NADH dehydrogenase | 0.0067 | 0.0727 | 0.0727 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0732 | 1 | 1 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0067 | 0.0727 | 0.2085 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0077 | 0.0863 | 0.0863 |
Trypanosoma brucei | NADPH:adrenodoxin oxidoreductase, mitochondrial, putative | 0.0067 | 0.0727 | 0.0727 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0067 | 0.0727 | 0.0688 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) | 0.0051 | 0.0493 | 0.1056 |
Mycobacterium ulcerans | monoxygenase | 0.0067 | 0.0727 | 0.2085 |
Plasmodium vivax | T-complex protein 1 subunit beta, putative | 0.0023 | 0.0115 | 0.0115 |
Plasmodium falciparum | thioredoxin reductase | 0.0254 | 0.3327 | 0.3327 |
Echinococcus multilocularis | sulfide:quinone oxidoreductase | 0.0067 | 0.0727 | 0.0727 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0254 | 0.3327 | 1 |
Entamoeba histolytica | disulphide oxidoreductase, putative | 0.0067 | 0.0727 | 1 |
Entamoeba histolytica | pyridine nucleotide-disulfide oxidoreductase family protein | 0.0067 | 0.0727 | 1 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0077 | 0.0863 | 0.0863 |
Schistosoma mansoni | glutamate synthase | 0.0067 | 0.0727 | 0.0727 |
Echinococcus multilocularis | dihydropyrimidine dehydrogenase (NADP+) | 0.0067 | 0.0727 | 0.0727 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0727 | 0.0727 |
Echinococcus multilocularis | glutamate synthase | 0.0067 | 0.0727 | 0.0727 |
Treponema pallidum | NADH oxidase | 0.0254 | 0.3327 | 1 |
Echinococcus granulosus | sulfide:quinone oxidoreductase | 0.0067 | 0.0727 | 0.0727 |
Echinococcus granulosus | pyridine nucleotide disulfide oxidoreductase | 0.0067 | 0.0727 | 0.0727 |
Mycobacterium ulcerans | NADPH dependent 2,4-dienoyl-CoA reductase FadH | 0.0067 | 0.0727 | 0.2085 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0067 | 0.0727 | 0.0688 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0067 | 0.0727 | 0.0727 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0254 | 0.3327 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0067 | 0.0727 | 0.0727 |
Toxoplasma gondii | hypothetical protein | 0.0027 | 0.0158 | 0.0158 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0254 | 0.3327 | 0.3327 |
Plasmodium falciparum | glutathione reductase | 0.0732 | 1 | 1 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0067 | 0.0727 | 0.0688 |
Mycobacterium leprae | Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate | 0.0067 | 0.0727 | 0.1795 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0077 | 0.0863 | 0.0524 |
Schistosoma mansoni | sulfide quinone reductase | 0.0067 | 0.0727 | 0.0727 |
Leishmania major | trypanothione reductase | 0.0732 | 1 | 1 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0254 | 0.3327 | 0.3327 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0059 | 0.061 | 0.061 |
Toxoplasma gondii | thioredoxin reductase | 0.0732 | 1 | 1 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0027 | 0.0158 | 0.0158 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.0863 | 0.0863 |
Trypanosoma cruzi | NADH dehydrogenase, putative | 0.0067 | 0.0727 | 0.0727 |
Mycobacterium leprae | Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) | 0.0067 | 0.0727 | 0.1795 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.