Detailed information for compound 1822228

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 445.356 | Formula: C20H25BrN6O
  • H donors: 2 H acceptors: 4 LogP: 3.58 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC[C@H]1CCCN1c1nc(NCc2cccc(c2)Br)c2c(n1)n(cn2)C(C)C
  • InChi: 1S/C20H25BrN6O/c1-13(2)27-12-23-17-18(22-10-14-5-3-6-15(21)9-14)24-20(25-19(17)27)26-8-4-7-16(26)11-28/h3,5-6,9,12-13,16,28H,4,7-8,10-11H2,1-2H3,(H,22,24,25)/t16-/m1/s1
  • InChiKey: TXTSLHCNXKTEFF-MRXNPFEDSA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens cyclin-dependent kinase 3 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus multilocularis cyclin dependent kinase Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma japonicum ko:K02090 cyclin-dependent kinase 5, putative Get druggable targets OG5_126712 All targets in OG5_126712
Brugia malayi Protein kinase domain containing protein Get druggable targets OG5_126712 All targets in OG5_126712
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania mexicana cell division related protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma cruzi cdc2-related kinase 3 Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus granulosus cyclin dependent kinase 5 Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus multilocularis cyclin dependent kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Cryptosporidium parvum Cdc2-like CDK2/CDC28 like protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania infantum cell division protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma congolense cdc2-related kinase 1, putative Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania mexicana cell division protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania infantum cell division related protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Plasmodium falciparum protein kinase 5 Get druggable targets OG5_126712 All targets in OG5_126712
Plasmodium vivax protein kinase Crk2 Get druggable targets OG5_126712 All targets in OG5_126712
Plasmodium yoelii cdc2-related kinase 2 Get druggable targets OG5_126712 All targets in OG5_126712
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Candida albicans Protein kinase that can substitute for S. cerevisiae CDC28 (YBR160W) main cell cycle cyclin-dependent kinase Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma cruzi cdc2-related kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania major cell division related protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania major cell division protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Babesia bovis cell division control protein 2, putative Get druggable targets OG5_126712 All targets in OG5_126712
Giardia lamblia Kinase, CMGC CDK Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus granulosus cyclin dependent kinase Get druggable targets OG5_126712 All targets in OG5_126712
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Cryptosporidium hominis cdc2-like protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Candida albicans Protein kinase that can substitute for S. cerevisiae CDC28 (YBR160W) main cell cycle cyclin-dependent kinase Get druggable targets OG5_126712 All targets in OG5_126712
Theileria parva cell division control protein 2 related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Plasmodium knowlesi Cell division control protein 2 homolog Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus multilocularis cyclin dependent kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus granulosus cyclin dependent kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma brucei gambiense cell division protein kinase 2 homolog 1,cdc2- like protein kinase, putative Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma brucei cdc2-related kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Entamoeba histolytica cell division protein kinase 2, putative Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus multilocularis cyclin dependent kinase 5 Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Plasmodium berghei cdc2-related kinase 2 Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania braziliensis cell division protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Brugia malayi cell division control protein 2 homolog Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania donovani cell division protein kinase 2 Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma cruzi cdc2-related kinase 3 Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma brucei cdc2-related kinase 3 Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma brucei gambiense cell division related protein kinase 2, putative,CDC2-related protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania donovani cdc2-related kinase 3, putative Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma cruzi cdc2-related kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Giardia lamblia Kinase, CMGC CDK Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma japonicum ko:K02087 cyclin-dependent kinase 1, putative Get druggable targets OG5_126712 All targets in OG5_126712
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma congolense cdc2-related kinase 3, putative Get druggable targets OG5_126712 All targets in OG5_126712
Neospora caninum CMGC kinase, CDK family TgPK2, putative Get druggable targets OG5_126712 All targets in OG5_126712
Entamoeba histolytica cell division protein kinase 2, putative Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania braziliensis cell division related protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712

By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Trypanosoma brucei mitogen-activated protein kinase 5 cyclin-dependent kinase 3 305 aa 303 aa 32.0 %

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0059 0.007 0.0143
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0113 0.02 0.0219
Schistosoma mansoni BC026374 protein (S09 family) 0.0057 0.0064 0.0073
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0144 0.0276 0.0274
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.1189 0.2816 0.7489
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0195 0.04 0.0398
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0059 0.007 0.0077
Plasmodium vivax hypothetical protein, conserved 0.0113 0.02 0.053
Schistosoma mansoni steroid hormone receptor ad4bp 0.007 0.0097 0.0111
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0308 0.0676 0.1251
Toxoplasma gondii DNA gyrase/topoisomerase IV, A subunit domain-containing protein 0.0078 0.0115 0.0306
Echinococcus multilocularis Protein lozenge 0.0065 0.0084 0.0092
Schistosoma mansoni aldehyde dehydrogenase 0.0195 0.04 0.0463
Schistosoma mansoni notch 0.0035 0.0013 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0013 0.0042
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0057 0.0064 0.0165
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (large chain) 0.008 0.0121 0.0314
Trichomonas vaginalis adenylate cyclase, putative 0.0044 0.0033 0.0103
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0316 0.0693 0.0758
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0316 0.0693 0.2459
Loa Loa (eye worm) voltage-dependent calcium channel 0.0077 0.0112 0.0228
Onchocerca volvulus Peroxidasin homolog 0.011 0.0193 0.0633
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0044 0.0137
Loa Loa (eye worm) jmjC domain-containing protein 0.0034 0.001 0.002
Echinococcus granulosus cpg binding protein 0.0061 0.0073 0.008
Echinococcus granulosus neuropeptide receptor 0.0308 0.0676 0.0739
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0713 0.166 0.1815
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.1189 0.2816 0.749
Echinococcus multilocularis fibropellin Ia 0.0035 0.0013 0.0014
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0057 0.0064 0.0073
Trichomonas vaginalis guanylate cyclase, putative 0.0044 0.0033 0.0103
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0308 0.0676 0.0783
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0235 0.0497 0.092
Echinococcus multilocularis short transient receptor potential channel 6 0.0059 0.007 0.0077
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0033 0.0007 0.0006
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.1189 0.2816 0.2815
Echinococcus granulosus shaker cognate 0.0059 0.007 0.0077
Loa Loa (eye worm) hypothetical protein 0.0037 0.0017 0.0034
Schistosoma mansoni blooms syndrome DNA helicase 0.0036 0.0014 0.0014
Brugia malayi tailless protein 0.0033 0.0007 0.0008
Echinococcus granulosus potassium voltage gated channel protein 0.0059 0.007 0.0077
Loa Loa (eye worm) hypothetical protein 0.0308 0.0676 0.1376
Mycobacterium ulcerans ferredoxin reductase 0.0316 0.0693 0.2456
Leishmania major trypanothione reductase 0.1577 0.376 0.3759
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0057 0.0064 0.0073
Schistosoma mansoni transient receptor potential channel 0.0059 0.007 0.0079
Trichomonas vaginalis CMGC family protein kinase 0.0153 0.0298 0.0937
Echinococcus granulosus Nuclear hormone receptor HR96 0.0033 0.0007 0.0008
Loa Loa (eye worm) steroid hormone receptor 0.007 0.0097 0.0198
Echinococcus multilocularis rhodopsin orphan GPCR 0.0308 0.0676 0.0739
Echinococcus multilocularis tyrosine protein kinase Blk 0.0034 0.0009 0.001
Mycobacterium ulcerans monoxygenase 0.0316 0.0693 0.2456
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.1093 0.2583 0.5258
Schistosoma mansoni voltage-gated potassium channel 0.0059 0.007 0.0079
Echinococcus granulosus neuropeptide receptor 0.0308 0.0676 0.0739
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0111 0.0195 0.0213
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0096 0.016 0.0521
Loa Loa (eye worm) hypothetical protein 0.0033 0.0007 0.0014
Schistosoma mansoni opsin-like receptor 0.0308 0.0676 0.0783
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0031 0.0003 0.0003
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0375 0.0838 0.1553
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0068 0.0092 0.0319
Mycobacterium ulcerans NADH dehydrogenase 0.0316 0.0693 0.2456
Toxoplasma gondii endonuclease IV APN 0.0075 0.0109 0.0289
Schistosoma mansoni hypothetical protein 0.02 0.0413 0.0478
Brugia malayi hypothetical protein 0.0073 0.0104 0.0188
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.1189 0.2816 0.3079
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0181 0.0366 0.04
Echinococcus granulosus sodium and chloride dependent glycine 0.0113 0.02 0.0219
Loa Loa (eye worm) hypothetical protein 0.007 0.0097 0.0198
Schistosoma mansoni hypothetical protein 0.0354 0.0788 0.0913
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0238 0.0505 0.1586
Brugia malayi Glutamate receptor 1 precursor 0.0159 0.0312 0.0575
Loa Loa (eye worm) glutathione reductase 0.1577 0.376 0.7655
Toxoplasma gondii hypothetical protein 0.0059 0.007 0.0186
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0308 0.0676 0.1376
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0316 0.0693 0.2179
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0624 0.1443 0.1578
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0013 0.0042
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (small chain) 0.0032 0.0005 0.0006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0107 0.0187 0.0586
Brugia malayi EGF-like domain containing protein 0.0035 0.0013 0.0019
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0044 0.0033 0.0067
Brugia malayi GnHR receptor homolog 0.0308 0.0676 0.1251
Echinococcus multilocularis notch 0.0035 0.0013 0.0014
Chlamydia trachomatis endonuclease IV 0.0075 0.0109 0.0326
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0085 0.0134 0.0146
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.1189 0.2816 1
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0111 0.0195 0.0358
Echinococcus multilocularis dnaJ subfamily C 6 0.0062 0.0076 0.0084
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.1503 0.3581 0.9524
Onchocerca volvulus 0.0035 0.0013 0.0019
Loa Loa (eye worm) hypothetical protein 0.027 0.0583 0.1188
Loa Loa (eye worm) hypothetical protein 0.0157 0.0307 0.0625
Onchocerca volvulus 0.0308 0.0676 0.2272
Brugia malayi cytochrome P450 0.0068 0.0092 0.0166
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0042 0.0028 0.0088
Echinococcus multilocularis protein jagged 1 0.0035 0.0013 0.0014
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0172 0.0345 0.0701
Loa Loa (eye worm) hypothetical protein 0.0308 0.0676 0.1376
Trichomonas vaginalis glucosylceramidase, putative 0.0879 0.2063 0.6482
Loa Loa (eye worm) G-protein coupled receptor 0.0308 0.0676 0.1376
Echinococcus granulosus potassium voltage gated channel protein 0.0059 0.007 0.0077
Brugia malayi Dopamine receptor 0.0308 0.0676 0.1251
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0195 0.04 0.0437
Loa Loa (eye worm) hypothetical protein 0.0036 0.0013 0.0027
Loa Loa (eye worm) hypothetical protein 0.0107 0.0187 0.038
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0048 0.0044 0.0042
Echinococcus granulosus histone lysine methyltransferase setb 0.0158 0.031 0.0339
Plasmodium vivax DNA gyrase subunit A, putative 0.0078 0.0115 0.0303
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0108 0.0189 0.0187
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0308 0.0676 0.0783
Brugia malayi Nuclear hormone receptor family member nhr-19 0.007 0.0097 0.0176
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0308 0.0676 0.0739
Onchocerca volvulus 0.0342 0.0759 0.2553
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0316 0.0693 0.2456
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0181 0.0365 0.0422
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0113 0.02 0.023
Onchocerca volvulus Protein ultraspiracle homolog 0.007 0.0097 0.0307
Echinococcus granulosus aryl hydrocarbon receptor 0.0041 0.0025 0.0027
Giardia lamblia Thioredoxin reductase 0.0316 0.0693 0.2459
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0068 0.0092 0.0319
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0068 0.0092 0.0238
Loa Loa (eye worm) hypothetical protein 0.0076 0.0112 0.0227
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0013 0.0042
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0035 0.0013 0.0019
Brugia malayi phosphofructokinase 0.0108 0.0189 0.0347
Trichomonas vaginalis glucosylceramidase, putative 0.0879 0.2063 0.6482
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0238 0.0505 0.1579
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.4144 1 1
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0129 0.0241 0.0239
Loa Loa (eye worm) animal heme peroxidase 0.011 0.0193 0.0394
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0057 0.0064 0.007
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0113 0.02 0.023
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0316 0.0693 0.1839
Onchocerca volvulus 0.0115 0.0207 0.0679
Echinococcus granulosus potassium voltage gated channel protein 0.0059 0.007 0.0077
Schistosoma mansoni notch 0.0035 0.0013 0.0012
Schistosoma mansoni sodium/chloride dependent transporter 0.0113 0.02 0.023
Echinococcus granulosus g protein coupled receptor 0.0308 0.0676 0.0739
Schistosoma mansoni myosin xvIII 0.0308 0.0676 0.0783
Schistosoma mansoni hypothetical protein 0.0035 0.0013 0.0012
Plasmodium vivax SET domain protein, putative 0.0158 0.031 0.0821
Loa Loa (eye worm) solute carrier family 6 member 4 0.0664 0.1541 0.3136
Schistosoma mansoni glutamate synthase 0.0316 0.0693 0.0804
Loa Loa (eye worm) hypothetical protein 0.0035 0.0013 0.0025
Mycobacterium leprae Possible regulatory protein 0.0041 0.0025 0.0034
Echinococcus multilocularis transcription factor Dp 1 0.0075 0.0108 0.0118
Brugia malayi Nuclear hormone receptor family member nhr-41 0.007 0.0097 0.0176
Brugia malayi hypothetical protein 0.0033 0.0007 0.0008
Leishmania major hypothetical protein, conserved 0.0059 0.007 0.0068
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.004 0.0024 0.0057
Schistosoma mansoni neuropeptide receptor 0.0308 0.0676 0.0783
Loa Loa (eye worm) hypothetical protein 0.0693 0.1611 0.328
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0151 0.0293 0.032
Onchocerca volvulus 0.0141 0.0269 0.0891
Trichomonas vaginalis PIKK family atypical protein kinase 0.0107 0.0187 0.0586
Brugia malayi Carboxylesterase family protein 0.0336 0.0744 0.1379
Onchocerca volvulus 0.0664 0.1541 0.5209
Echinococcus multilocularis g-protein coupled receptor 0.0308 0.0676 0.0739
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.1189 0.2816 0.3079
Echinococcus multilocularis hyperpolarization activated cyclic 0.0075 0.0108 0.0118
Trichomonas vaginalis PIKK family atypical protein kinase 0.0086 0.0135 0.0426
Echinococcus granulosus protein jagged 2 0.0035 0.0013 0.0014
Loa Loa (eye worm) jmjC domain-containing protein 0.012 0.0217 0.0442
Plasmodium falciparum FAD-linked sulfhydryl oxidase ERV1, putative 0.0109 0.0191 0.0502
Echinococcus granulosus neuropeptide s receptor 0.1753 0.4188 0.4578
Loa Loa (eye worm) hypoxia-induced factor 1 0.0483 0.11 0.224
Brugia malayi Calcium binding EGF domain containing protein 0.0035 0.0013 0.0019
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0151 0.0293 0.032
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0238 0.0505 0.1586
Brugia malayi hypoxia-induced factor 1 0.0483 0.11 0.204
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0075 0.0109 0.0269
Echinococcus granulosus two pore calcium channel protein 1 0.0059 0.007 0.0077
Echinococcus granulosus nuclear receptor 2DBD gamma 0.007 0.0097 0.0106
Loa Loa (eye worm) hypothetical protein 0.0424 0.0957 0.1949
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0054 0.0057 0.0055
Schistosoma mansoni voltage-gated potassium channel 0.0059 0.007 0.0079
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0049 0.0045 0.0141
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0059 0.007 0.0079
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.0621 0.1952
Trichomonas vaginalis chromobox protein, putative 0.0151 0.0293 0.0921
Trichomonas vaginalis glucosylceramidase, putative 0.0926 0.2178 0.6843
Loa Loa (eye worm) neuropeptide F receptor 0.0308 0.0676 0.1376
Echinococcus multilocularis rhodopsin orphan GPCR 0.0308 0.0676 0.0739
Trichomonas vaginalis conserved hypothetical protein 0.009 0.0146 0.0459
Brugia malayi bHLH-PAS transcription factor 0.0115 0.0207 0.038
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0059 0.007 0.0079
Brugia malayi glutathione reductase 0.1577 0.376 0.6984
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0073 0.0104 0.0114
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.006 0.0071 0.0078
Echinococcus multilocularis glutamate receptor 2 0.0113 0.0201 0.022
Trichomonas vaginalis glucosylceramidase, putative 0.1339 0.3183 1
Echinococcus granulosus voltage gated potassium channel 0.0059 0.007 0.0077
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0316 0.0693 0.1844
Loa Loa (eye worm) CHromoDomain protein family member 0.0039 0.0021 0.0043
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0316 0.0693 0.8273
Brugia malayi Cadherin domain containing protein 0.0035 0.0013 0.0019
Echinococcus multilocularis acetylcholinesterase 0.0336 0.0744 0.0813
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.007 0.0097 0.0307
Plasmodium vivax DNA topoisomerase II, putative 0.0375 0.0838 0.2226
Brugia malayi G-protein coupled receptor 0.0308 0.0676 0.1251
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.3494 0.842 0.8419
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0316 0.0693 0.2179
Loa Loa (eye worm) hypothetical protein 0.0057 0.0064 0.0131
Loa Loa (eye worm) hepatopoietin HPO2 0.0109 0.0191 0.0388
Schistosoma mansoni chromobox protein 0.0151 0.0293 0.0338
Brugia malayi Nuclear hormone receptor E75 0.0033 0.0007 0.0008
Echinococcus granulosus glutamate receptor 2 0.0181 0.0366 0.04
Schistosoma mansoni zinc finger protein 0.0033 0.0007 0.0006
Loa Loa (eye worm) hypothetical protein 0.0035 0.0013 0.0025
Loa Loa (eye worm) hypothetical protein 0.011 0.0193 0.0394
Brugia malayi Carboxylesterase family protein 0.0057 0.0064 0.0115
Loa Loa (eye worm) CXXC zinc finger family protein 0.0057 0.0066 0.0133
Echinococcus granulosus cytoplasmic intermediate filament protein 0.004 0.0022 0.0024
Schistosoma mansoni ap endonuclease 0.006 0.0071 0.008
Onchocerca volvulus Peroxidase homolog 0.011 0.0193 0.0633
Loa Loa (eye worm) hypothetical protein 0.0059 0.007 0.0143
Trichomonas vaginalis spcc417.12 protein, putative 0.0057 0.0064 0.0202
Loa Loa (eye worm) doublecortin family protein 0.0157 0.0307 0.0625
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0036 0.0013 0.0013
Schistosoma mansoni serine/threonine protein kinase 0.0054 0.0057 0.0064
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0068 0.0092 0.0319
Loa Loa (eye worm) hypothetical protein 0.0059 0.007 0.0143
Brugia malayi hypothetical protein 0.0033 0.0007 0.0008
Echinococcus multilocularis g protein coupled receptor 0.0308 0.0676 0.0739
Echinococcus granulosus rhodopsin orphan GPCR 0.0308 0.0676 0.0739
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0316 0.0693 0.0758
Echinococcus granulosus notch 0.0035 0.0013 0.0014
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0059 0.007 0.0126
Echinococcus granulosus transcription factor Dp 1 0.0075 0.0108 0.0118
Onchocerca volvulus 0.0035 0.0013 0.0019
Echinococcus multilocularis peregrin 0.0058 0.0067 0.0073
Echinococcus granulosus chromobox protein 1 0.0151 0.0293 0.032
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0036 0.0013 0.0042
Echinococcus granulosus peroxidasin 0.0114 0.0203 0.0221
Onchocerca volvulus 0.0308 0.0676 0.2272
Schistosoma mansoni hypothetical protein 0.0308 0.0676 0.0783
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.007 0.0097 0.0111
Schistosoma mansoni voltage-gated potassium channel 0.0059 0.007 0.0079
Loa Loa (eye worm) hypothetical protein 0.0235 0.0497 0.1012
Echinococcus granulosus tyrosine protein kinase Fyn 0.0038 0.0018 0.0019
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0308 0.0676 0.0783
Echinococcus multilocularis neurogenic locus notch protein 0.0035 0.0013 0.0014
Mycobacterium ulcerans aldehyde dehydrogenase 0.0195 0.04 0.1415
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0349 0.0775 0.1579
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0144 0.0276 0.0274
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0038 0.0018 0.0019
Echinococcus multilocularis ryanodine receptor 44f 0.0059 0.007 0.0077
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0181 0.0365 0.0965
Onchocerca volvulus 0.0082 0.0125 0.0402
Schistosoma mansoni histamine h1 receptor 0.0308 0.0676 0.0783
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0308 0.0676 0.0783
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0034 0.001 0.0008
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0316 0.0693 0.1844
Loa Loa (eye worm) TYRA-2 protein 0.0308 0.0676 0.1376
Brugia malayi hypothetical protein 0.0523 0.1199 0.2224
Loa Loa (eye worm) heterochromatin protein 1 0.0151 0.0293 0.0596
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0316 0.0693 0.0758
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0054 0.0057 0.0117
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0075 0.0109 0.0282
Echinococcus granulosus netrin receptor unc 5 0.0048 0.0042 0.0046
Loa Loa (eye worm) thioredoxin reductase 0.1577 0.376 0.7655
Mycobacterium ulcerans glutaminase 0.0278 0.0602 0.2132
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0316 0.0693 0.0691
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0121 0.0219 0.0689
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0068 0.0092 0.0319
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0059 0.007 0.0126
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.0152 0.0174
Treponema pallidum oxidoreductase 0.0316 0.0693 0.2415
Echinococcus multilocularis FTZ F1 alpha 0.007 0.0097 0.0106
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.0621 0.1952
Loa Loa (eye worm) hypothetical protein 0.0308 0.0676 0.1376
Entamoeba histolytica thioredoxin reductase, putative 0.0316 0.0693 0.8273
Toxoplasma gondii PHD-finger domain-containing protein 0.0058 0.0067 0.0178
Schistosoma mansoni aryl hydrocarbon receptor 0.0156 0.0306 0.0353
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0059 0.007 0.0214
Echinococcus multilocularis NMDA receptor 0.0068 0.0091 0.01
Echinococcus granulosus thioredoxin glutathione reductase 0.1577 0.376 0.411
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0048 0.0044 0.0048
Brugia malayi Valyl-tRNA synthetase 0.0036 0.0013 0.002
Chlamydia trachomatis DNA gyrase subunit B 0.018 0.0364 0.1239
Schistosoma mansoni hypothetical protein 0.0035 0.0013 0.0012
Loa Loa (eye worm) inositol-1 0.0238 0.0505 0.1028
Loa Loa (eye worm) hypothetical protein 0.0598 0.1379 0.2808
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0031 0.0003 0.0001
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0068 0.0092 0.0238
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0144 0.0276 0.0509
Brugia malayi hypothetical protein 0.0142 0.0271 0.0498
Brugia malayi putative neuropeptide receptor NPR1 0.0308 0.0676 0.1251
Echinococcus multilocularis geminin 0.0907 0.2131 0.233
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.3494 0.842 0.8419
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0081 0.0124 0.0226
Trichomonas vaginalis PIKK family atypical protein kinase 0.0115 0.0205 0.0643
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0368 0.082 0.0818
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0108 0.0189 0.0614
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0068 0.0092 0.0238
Trypanosoma brucei hypothetical protein, conserved 0.0316 0.0693 0.0691
Loa Loa (eye worm) G-protein coupled receptor 0.0308 0.0676 0.1376
Echinococcus multilocularis fat cadherin tumor suppressor 0.0035 0.0013 0.0014
Trypanosoma cruzi PAB1-binding protein , putative 0.0106 0.0184 0.0182
Echinococcus multilocularis rhodopsin orphan GPCR 0.0308 0.0676 0.0739
Echinococcus granulosus tyrosine protein kinase Src42A 0.0038 0.0018 0.0019
Brugia malayi nuclear hormone receptor 0.0033 0.0007 0.0008
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0093 0.0152 0.0166
Schistosoma mansoni hypothetical protein 0.0062 0.0076 0.0087
Giardia lamblia GTOR 0.0144 0.0276 0.0978
Schistosoma mansoni vesicular amine transporter 0.0059 0.007 0.0079
Loa Loa (eye worm) jmjC domain-containing protein 0.0034 0.001 0.002
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0033 0.0007 0.0008
Schistosoma mansoni neuroligin 3 (S09 family) 0.0057 0.0064 0.0073
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0033 0.0007 0.0014
Schistosoma mansoni slit 0.0035 0.0013 0.0012
Schistosoma mansoni cytochrome P450 0.0068 0.0092 0.0105
Loa Loa (eye worm) jmjC domain-containing protein 0.0034 0.001 0.002
Echinococcus granulosus intermediate filament protein 0.0082 0.0125 0.0137
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0121 0.0219 0.0689
Mycobacterium ulcerans DNA gyrase subunit A 0.0078 0.0115 0.0402
Loa Loa (eye worm) PHD-finger family protein 0.0058 0.0067 0.0137
Schistosoma mansoni rab6-interacting 0.0157 0.0307 0.0355
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.0621 0.1952
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.007 0.0097 0.0111
Echinococcus multilocularis neuropeptide receptor A26 0.1753 0.4188 0.4578
Echinococcus granulosus neuropeptides capa receptor 0.0308 0.0676 0.0739
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0073 0.0104 0.0114
Brugia malayi G protein-coupled receptor 0.0308 0.0676 0.1251
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0068 0.0091 0.01
Echinococcus granulosus fmrfamide receptor 0.0308 0.0676 0.0739
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0084 0.0095
Onchocerca volvulus 0.0308 0.0676 0.2272
Giardia lamblia Kinase, CMGC CDK 0.0054 0.0057 0.0201
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0316 0.0693 0.0691
Brugia malayi hypothetical protein 0.0308 0.0676 0.1251
Treponema pallidum sodium- and chloride- dependent transporter 0.0664 0.1541 0.5442
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0059 0.007 0.0126
Trichomonas vaginalis ap endonuclease, putative 0.006 0.0071 0.0224
Echinococcus multilocularis neuropeptide Y receptor 0.0308 0.0676 0.0739
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.004 0.0022 0.0024
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0059 0.007 0.0077
Brugia malayi hypothetical protein 0.0308 0.0676 0.1251
Echinococcus granulosus glutamate receptor 2 0.0113 0.0201 0.022
Schistosoma mansoni ap endonuclease 0.006 0.0071 0.008
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0151 0.0293 0.032
Echinococcus multilocularis rhodopsin orphan GPCR 0.0308 0.0676 0.0739
Echinococcus granulosus peptide allatostatin:somatostatin 0.0308 0.0676 0.0739
Brugia malayi Nuclear hormone receptor family member nhr-25 0.007 0.0097 0.0176
Brugia malayi ecdysteroid receptor 0.007 0.0097 0.0176
Echinococcus multilocularis bloom syndrome protein 0.0046 0.0037 0.004
Loa Loa (eye worm) hypothetical protein 0.0713 0.166 0.338
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0036 0.0013 0.0042
Schistosoma mansoni hypothetical protein 0.0115 0.0206 0.0237
Brugia malayi Protein kinase domain containing protein 0.0054 0.0057 0.0102
Brugia malayi hypothetical protein 0.0308 0.0676 0.1251
Loa Loa (eye worm) hypothetical protein 0.0308 0.0676 0.1376
Loa Loa (eye worm) hypothetical protein 0.0519 0.1187 0.2417
Echinococcus multilocularis neuropeptide Y receptor 0.0308 0.0676 0.0739
Trichomonas vaginalis glucosylceramidase, putative 0.1339 0.3183 1
Loa Loa (eye worm) hypothetical protein 0.011 0.0193 0.0394
Trypanosoma cruzi target of rapamycin kinase 3 0.0115 0.0205 0.0203
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0037 0.0017 0.0017
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0038 0.0018 0.0019
Echinococcus granulosus cytochrome P450 2K1 0.0068 0.0092 0.01
Brugia malayi Furin-like cysteine rich region family protein 0.0147 0.0283 0.0522
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.007 0.0097 0.0198
Brugia malayi Transient-receptor-potential like protein 0.0059 0.007 0.0126
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0048 0.0044 0.0042
Loa Loa (eye worm) phosphatidylinositol 3 0.0048 0.0044 0.0089
Echinococcus granulosus nmda type glutamate receptor 0.01 0.0168 0.0184
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0113 0.02 0.0533
Toxoplasma gondii ATP-binding cassette G family transporter ABCG84 0.0031 0.0002 0.0005
Loa Loa (eye worm) hypothetical protein 0.011 0.0193 0.0394
Brugia malayi Pre-SET motif family protein 0.1093 0.2583 0.4796
Echinococcus granulosus transient receptor potential cation channel 0.0059 0.007 0.0077
Loa Loa (eye worm) hypothetical protein 0.007 0.0097 0.0198
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0129 0.0241 0.2873
Brugia malayi Calcitonin receptor-like protein seb-1 0.0349 0.0775 0.1437
Brugia malayi hypothetical protein 0.0342 0.0759 0.1405
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0044 0.0033 0.0036
Trichomonas vaginalis glutathione reductase, putative 0.1189 0.2816 0.8849
Trichomonas vaginalis CMGC family protein kinase 0.0153 0.0298 0.0937
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0059 0.007 0.0077
Loa Loa (eye worm) hypothetical protein 0.0035 0.0013 0.0025
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0075 0.0108 0.0118
Giardia lamblia Kinase, CMGC MAPK 0.0153 0.0298 0.1056
Loa Loa (eye worm) RecQ helicase 0.0046 0.0037 0.0076
Brugia malayi hypothetical protein 0.0037 0.0017 0.0026
Loa Loa (eye worm) hypothetical protein 0.0059 0.007 0.0143
Brugia malayi hypothetical protein 0.0308 0.0676 0.1251
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0336 0.0744 0.0863
Mycobacterium tuberculosis Carboxylesterase LipT 0.0057 0.0064 0.0165
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0068 0.0092 0.0319
Loa Loa (eye worm) nuclear receptor NHR-67 0.0033 0.0007 0.0014
Trypanosoma brucei cdc2-related kinase 3 0.0054 0.0057 0.0055
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0172 0.0345 0.0377
Echinococcus multilocularis adenylate cyclase 9 0.0076 0.0112 0.0122
Echinococcus granulosus neuropeptide receptor A26 0.1753 0.4188 0.4578
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0044 0.0137
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.007 0.0097 0.0111
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.003 0.0095
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.014 0.0267 0.0704
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0068 0.0092 0.0319
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0059 0.007 0.0214
Loa Loa (eye worm) hypothetical protein 0.0033 0.0007 0.0014
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0151 0.0293 0.0338
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0129 0.0241 0.0263
Brugia malayi hypothetical protein 0.0059 0.007 0.0126
Loa Loa (eye worm) ryanodine receptor 0.0059 0.007 0.0143
Brugia malayi Nuclear hormone receptor-like 1 0.0037 0.0017 0.0026
Schistosoma mansoni jumonji domain containing protein 0.0034 0.001 0.0009
Brugia malayi latrophilin 2 splice variant baaae 0.0239 0.0507 0.0937
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0044 0.0137
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0039 0.0021 0.0023
Loa Loa (eye worm) hypothetical protein 0.0141 0.0269 0.0548
Leishmania major hypothetical protein, unknown function 0.0059 0.007 0.0068
Brugia malayi EGF-like domain containing protein 0.0035 0.0013 0.0019
Echinococcus multilocularis rhodopsin orphan GPCR 0.0308 0.0676 0.0739
Trichomonas vaginalis aldehyde oxidase, putative 0.017 0.0338 0.1063
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.063 0.1458 0.3874
Echinococcus multilocularis potassium voltage gated channel protein 0.0059 0.007 0.0077
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.007 0.0097 0.0198
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0059 0.007 0.0079
Schistosoma mansoni nuclear hormone receptor 0.007 0.0097 0.0111
Echinococcus multilocularis carboxylesterase 5A 0.0336 0.0744 0.0813
Brugia malayi cation channel family protein 0.0059 0.007 0.0126
Echinococcus granulosus mitogen activated protein kinase 0.0153 0.0298 0.0326
Loa Loa (eye worm) hypothetical protein 0.0111 0.0195 0.0397
Mycobacterium ulcerans 6-phosphofructokinase 0.0108 0.0189 0.0665
Loa Loa (eye worm) hypothetical protein 0.0308 0.0676 0.1376
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0049 0.0045 0.0141
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0059 0.0185
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0308 0.0676 0.0739
Toxoplasma gondii hypothetical protein 0.0059 0.007 0.0186
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0036 0.0013 0.0036
Entamoeba histolytica hypothetical protein 0.0073 0.0104 0.124
Trichomonas vaginalis glucosylceramidase, putative 0.0879 0.2063 0.6482
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0044 0.0033 0.0067
Plasmodium falciparum ataxin-2 like protein, putative 0.0106 0.0184 0.0485
Echinococcus granulosus dnaJ subfamily B 0.0816 0.191 0.2088
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0003 0.0003
Echinococcus multilocularis epidermal growth factor receptor 0.0147 0.0283 0.031
Loa Loa (eye worm) hypothetical protein 0.011 0.0193 0.0394
Brugia malayi RNA binding protein 0.0065 0.0084 0.0151
Leishmania major dihydrolipoamide dehydrogenase, putative 0.1189 0.2816 0.2815
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0084 0.0095
Loa Loa (eye worm) 6-phosphofructokinase 0.0108 0.0189 0.0385
Brugia malayi hypothetical protein 0.0037 0.0017 0.0026
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0054 0.0057 0.0117
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0181 0.0366 0.04
Brugia malayi hypothetical protein 0.0308 0.0676 0.1251
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0068 0.0092 0.0319
Brugia malayi Nuclear hormone receptor family member nhr-31 0.007 0.0097 0.0176
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0316 0.0693 0.0691
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0037 0.0017 0.0039
Trichomonas vaginalis PIKK family atypical protein kinase 0.0097 0.0161 0.0506
Loa Loa (eye worm) hypothetical protein 0.0308 0.0676 0.1376
Loa Loa (eye worm) TK/EGFR protein kinase 0.0147 0.0283 0.0577
Loa Loa (eye worm) hypothetical protein 0.0664 0.1541 0.3136
Giardia lamblia PHD finger protein 15 0.0058 0.0067 0.0235
Schistosoma mansoni hypothetical protein 0.0044 0.0033 0.0036
Echinococcus granulosus g protein coupled receptor 0.0308 0.0676 0.0739
Brugia malayi Animal haem peroxidase family protein 0.011 0.0193 0.0355
Brugia malayi hypothetical protein 0.0157 0.0307 0.0566
Loa Loa (eye worm) hypothetical protein 0.0057 0.0064 0.0131
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0049 0.0045 0.0141
Schistosoma mansoni inositol monophosphatase 0.0238 0.0505 0.0585
Loa Loa (eye worm) hypothetical protein 0.0034 0.001 0.002
Brugia malayi Bloom's syndrome protein homolog 0.0046 0.0037 0.0064
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0113 0.02 0.0408
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.014 0.0267 0.0711
Schistosoma mansoni transcription factor LCR-F1 0.0073 0.0104 0.0118
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0059 0.007 0.0126
Plasmodium falciparum amino acid transporter, putative 0.0113 0.02 0.0527
Echinococcus multilocularis allatostatin A receptor 0.0308 0.0676 0.0739
Brugia malayi Animal haem peroxidase family protein 0.011 0.0193 0.0355
Schistosoma mansoni hypothetical protein 0.0068 0.0092 0.0105
Echinococcus granulosus single minded 2 0.0126 0.0233 0.0255
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0105 0.0182 0.0199
Loa Loa (eye worm) hypothetical protein 0.0114 0.0203 0.0412
Giardia lamblia Glutamate synthase 0.0316 0.0693 0.2459
Loa Loa (eye worm) hypothetical protein 0.155 0.3694 0.752
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0316 0.0693 0.1844
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0258 0.0553 0.1855
Schistosoma mansoni voltage-gated cation channel 0.0151 0.0293 0.0338
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0048 0.0044 0.0042
Loa Loa (eye worm) hypothetical protein 0.0308 0.0676 0.1376
Echinococcus multilocularis dro:myosuppressin receptor 0.0308 0.0676 0.0739
Echinococcus granulosus FTZ F1 alpha 0.007 0.0097 0.0106
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0059 0.007 0.0077
Echinococcus multilocularis transient receptor potential cation channel 0.0059 0.007 0.0077
Loa Loa (eye worm) hypothetical protein 0.0037 0.0017 0.0034
Schistosoma mansoni hypothetical protein 0.0308 0.0676 0.0783
Treponema pallidum exodeoxyribonuclease (exoA) 0.006 0.0071 0.0193
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0013 0.0042
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0068 0.0091 0.01
Schistosoma mansoni opsin-like receptor 0.0308 0.0676 0.0783
Entamoeba histolytica hypothetical protein 0.0073 0.0104 0.124
Trichomonas vaginalis chromobox protein, putative 0.0036 0.0013 0.0042
Brugia malayi ERG2 and Sigma1 receptor like protein 0.155 0.3694 0.6861
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0048 0.0042 0.0046
Loa Loa (eye worm) hypothetical protein 0.011 0.0193 0.0394
Trichomonas vaginalis hypothetical protein 0.0036 0.0013 0.0042
Brugia malayi ORL1-like opioid receptor 0.0308 0.0676 0.1251
Brugia malayi hypothetical protein 0.0106 0.0184 0.0338
Trichomonas vaginalis set domain proteins, putative 0.1244 0.2949 0.9267
Echinococcus multilocularis calcium activated potassium channel 0.0062 0.0076 0.0083
Schistosoma mansoni tyrosine kinase 0.0038 0.0018 0.0018
Echinococcus multilocularis sodium channel protein 0.0713 0.166 0.1815
Schistosoma mansoni glutamate receptor kainate 0.0159 0.0312 0.036
Trypanosoma cruzi trypanothione reductase, putative 0.1577 0.376 0.3759
Echinococcus multilocularis chromobox protein 1 0.0151 0.0293 0.032
Loa Loa (eye worm) hypothetical protein 0.007 0.0097 0.0198
Schistosoma mansoni notch 0.0035 0.0013 0.0012
Echinococcus multilocularis neuroligin 0.0057 0.0064 0.007
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0059 0.007 0.0068
Echinococcus granulosus somatostatin receptor 0.0308 0.0676 0.0739
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.1189 0.2816 0.3272
Echinococcus multilocularis transient receptor potential cation channel 0.0059 0.007 0.0077
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0013 0.0042
Echinococcus granulosus g-protein coupled receptor 0.0308 0.0676 0.0739
Trypanosoma brucei PAB1-binding protein , putative 0.0106 0.0184 0.0182
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0308 0.0676 0.0783
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.1339 0.3183 0.5911
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0049 0.0045 0.0141
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0054 0.0057 0.0063
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0676 0.1569 0.1567
Loa Loa (eye worm) adenylyl cyclase 3 0.0076 0.0112 0.0227
Trichomonas vaginalis chromobox protein, putative 0.0096 0.016 0.0504
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0038 0.0018 0.0019
Onchocerca volvulus 0.0157 0.0307 0.1019
Schistosoma mansoni biogenic amine receptor 0.0308 0.0676 0.0783
Brugia malayi nuclear receptor NHR-88 0.007 0.0097 0.0176
Trypanosoma brucei ERV/ALR sulfhydryl oxidase domain-containing protein 0.0109 0.0191 0.0189
Echinococcus multilocularis microtubule associated protein 2 0.3569 0.8602 0.9403
Echinococcus multilocularis ATP binding cassette sub family G 0.0031 0.0002 0.0002
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0068 0.0092 0.0238
Loa Loa (eye worm) hypothetical protein 0.0035 0.0013 0.0025
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0068 0.0092 0.0238
Echinococcus multilocularis glutamate synthase 0.0316 0.0693 0.0758
Onchocerca volvulus 0.007 0.0097 0.0307
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0038 0.0018 0.0019
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0068 0.0092 0.009
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0068 0.0092 0.0319
Brugia malayi nuclear receptor RXR 0.0033 0.0007 0.0008
Brugia malayi sulfakinin receptor protein 0.0308 0.0676 0.1251
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0181 0.0366 0.04
Echinococcus granulosus 7tm_1 domain containing protein 0.0308 0.0676 0.0739
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0113 0.02 0.0367
Brugia malayi glutaminase DH11.1 0.0278 0.0602 0.1114
Echinococcus granulosus rhodopsin orphan GPCR 0.0308 0.0676 0.0739
Schistosoma mansoni voltage-dependent calcium channel 0.0059 0.007 0.0079
Echinococcus multilocularis neural cadherin 0.0035 0.0013 0.0014
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0151 0.0293 0.032
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0316 0.0693 0.8273
Onchocerca volvulus 0.0073 0.0104 0.0328
Loa Loa (eye worm) hypothetical protein 0.0059 0.007 0.0143
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.063 0.1458 0.3874
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0068 0.0092 0.0238
Loa Loa (eye worm) hypothetical protein 0.0059 0.007 0.0143
Echinococcus granulosus GPCR family 2 0.0111 0.0195 0.0213
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0108 0.0189 0.0497
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0039 0.0021 0.0022
Loa Loa (eye worm) hypothetical protein 0.007 0.0097 0.0198
Giardia lamblia Fructose-bisphosphate aldolase 0.0286 0.0621 0.2204
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0213 0.0444 0.1209
Onchocerca volvulus 0.0316 0.0693 0.2331
Echinococcus granulosus tyrosine protein kinase Src42A 0.0032 0.0005 0.0005
Brugia malayi MH2 domain containing protein 0.0238 0.0505 0.0934
Brugia malayi jmjC domain containing protein 0.0248 0.053 0.098
Trichomonas vaginalis glucosylceramidase, putative 0.0926 0.2178 0.6843
Entamoeba histolytica cell division protein kinase 2, putative 0.0054 0.0057 0.0684
Schistosoma mansoni amine GPCR 0.0308 0.0676 0.0783
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.063 0.1458 0.4051
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0075 0.0108 0.0338
Schistosoma mansoni survival motor neuron protein 0.02 0.0413 0.0478
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0368 0.082 0.0818
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.006 0.0071 0.0186
Schistosoma mansoni laminin gamma-3 chain 0.0035 0.0013 0.0012
Echinococcus granulosus Chromo domain 0.0036 0.0013 0.0015
Trichomonas vaginalis PIKK family atypical protein kinase 0.0144 0.0276 0.0868
Brugia malayi voltage-dependent calcium channel 0.0059 0.007 0.0126
Loa Loa (eye worm) isocitrate dehydrogenase 0.0031 0.0003 0.0005
Echinococcus multilocularis ecdysone induced protein 78C 0.007 0.0097 0.0106
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0169 0.0336 0.0367
Echinococcus multilocularis neurogenic locus notch protein 4 0.0035 0.0013 0.0014
Echinococcus granulosus voltage gated hydrogen channel 1 0.0059 0.007 0.0077
Loa Loa (eye worm) animal heme peroxidase 0.011 0.0193 0.0394
Echinococcus granulosus hypothetical protein 0.3213 0.7736 0.8456
Schistosoma mansoni voltage-gated potassium channel 0.0085 0.0134 0.0153
Loa Loa (eye worm) hypothetical protein 0.0057 0.0064 0.0131
Schistosoma mansoni single-minded 0.0156 0.0306 0.0353
Schistosoma mansoni hypothetical protein 0.0073 0.0104 0.0118
Trypanosoma brucei trypanothione reductase 0.1577 0.376 0.3759
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0033 0.0007 0.0008
Loa Loa (eye worm) hypothetical protein 0.0035 0.0013 0.0025
Echinococcus multilocularis cyclin dependent kinase 5 0.0054 0.0057 0.0063
Schistosoma mansoni 6-phosphofructokinase 0.0108 0.0189 0.0218
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0044 0.0137
Loa Loa (eye worm) hypothetical protein 0.2051 0.4912 1
Echinococcus multilocularis transient receptor potential cation channel 0.0059 0.007 0.0077
Schistosoma mansoni ankyrin 23/unc44 0.0044 0.0033 0.0036
Echinococcus granulosus death domain containing protein 0.0044 0.0033 0.0036
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0113 0.02 0.0219
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.007 0.0097 0.0198
Schistosoma mansoni tyrosine kinase 0.0038 0.0018 0.0018
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.007 0.0097 0.0106
Plasmodium falciparum ferrodoxin reductase-like protein 0.0316 0.0693 0.184
Entamoeba histolytica hypothetical protein 0.0073 0.0104 0.124
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.007 0.0097 0.0111
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0181 0.0365 0.1291
Echinococcus granulosus biogenic amine 5HT receptor 0.0818 0.1914 0.2092
Trichomonas vaginalis PIKK family atypical protein kinase 0.0144 0.0276 0.0868
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0238 0.0505 0.0503
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0113 0.02 0.0367
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0048 0.0044 0.0042
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0036 0.0013 0.0013
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.3494 0.842 0.8419
Trichomonas vaginalis glucosylceramidase, putative 0.1339 0.3183 1
Echinococcus granulosus epidermal growth factor receptor 0.0147 0.0283 0.031
Trichomonas vaginalis PIKK family atypical protein kinase 0.0115 0.0205 0.0643
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0308 0.0676 0.0783
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0034 0.0009 0.001
Trichomonas vaginalis inositol monophosphatase, putative 0.0238 0.0505 0.1586
Loa Loa (eye worm) hypothetical protein 0.0308 0.0676 0.1376
Brugia malayi olfactory channel protein osm-9 0.006 0.0072 0.0128
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0068 0.0092 0.0319
Echinococcus multilocularis PHD finger protein rhinoceros 0.0058 0.0067 0.0073
Loa Loa (eye worm) hypothetical protein 0.0037 0.0017 0.0034
Schistosoma mansoni nuclear receptor 0.0033 0.0007 0.0006
Echinococcus granulosus chromobox protein 2 0.0036 0.0013 0.0015
Schistosoma mansoni intermediate filament proteins 0.0082 0.0125 0.0143
Echinococcus granulosus sodium leak channel non selective protein 0.0059 0.007 0.0077
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.006 0.0071 0.0069
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0316 0.0693 0.2179
Plasmodium vivax heterochromatin protein 1, putative 0.0036 0.0013 0.0032
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.1189 0.2816 1
Echinococcus multilocularis serotonin receptor 0.0818 0.1914 0.2092
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0036 0.0013 0.0015
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.007 0.0097 0.0198
Loa Loa (eye worm) hypothetical protein 0.0075 0.0108 0.0219
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0153 0.0298 0.0296
Onchocerca volvulus 0.0308 0.0676 0.2272
Brugia malayi Carboxylesterase family protein 0.0057 0.0064 0.0115
Echinococcus multilocularis ATP binding cassette sub family G 0.0031 0.0002 0.0002
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0044 0.0033 0.0103
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0068 0.0092 0.0238
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0037 0.0017 0.0034
Loa Loa (eye worm) hypothetical protein 0.0035 0.0013 0.0025
Schistosoma mansoni jumonji domain containing protein 0.0209 0.0435 0.0503
Loa Loa (eye worm) hypothetical protein 0.007 0.0097 0.0198
Echinococcus granulosus dnaJ subfamily C 6 0.0062 0.0076 0.0084
Brugia malayi Death domain containing protein 0.0044 0.0033 0.0056
Echinococcus granulosus BC026374 protein S09 family 0.0057 0.0064 0.007
Echinococcus granulosus 6 phosphofructokinase 0.0108 0.0189 0.0207
Loa Loa (eye worm) hypothetical protein 0.0035 0.0013 0.0025
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0068 0.0092 0.0238
Loa Loa (eye worm) hypothetical protein 0.006 0.0073 0.0149
Echinococcus multilocularis tar DNA binding protein 0.0065 0.0084 0.0091
Loa Loa (eye worm) hypothetical protein 0.0308 0.0676 0.1376
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0316 0.0693 0.184
Schistosoma mansoni phd/f-box containing protein 0.0034 0.001 0.0009
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0059 0.007 0.0126
Schistosoma mansoni lipoxygenase 0.0342 0.0758 0.0879
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0153 0.0298 0.0296
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0038 0.0018 0.0019
Trichomonas vaginalis PIKK family atypical protein kinase 0.0085 0.0133 0.0419
Schistosoma mansoni voltage-gated potassium channel 0.0059 0.007 0.0079
Schistosoma mansoni nuclear receptor 0.0033 0.0007 0.0006
Echinococcus granulosus cyclin dependent kinase 5 0.0054 0.0057 0.0063
Loa Loa (eye worm) 6-phosphofructokinase 0.0108 0.0189 0.0385
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.007 0.0097 0.0106
Brugia malayi Uncoordinated protein 44 0.0044 0.0033 0.0056
Loa Loa (eye worm) hypothetical protein 0.0033 0.0007 0.0014
Brugia malayi orphan nuclear receptor NR2E1 0.0033 0.0007 0.0008
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0003 0.0003
Echinococcus multilocularis somatostatin receptor 0.0308 0.0676 0.0739
Brugia malayi jmjC domain containing protein 0.0034 0.001 0.0013
Plasmodium vivax amine transporter, putative 0.0113 0.02 0.053
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0158 0.031 0.0358
Loa Loa (eye worm) hypothetical protein 0.011 0.0193 0.0394
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.02 0.0413 0.0764
Brugia malayi AKH receptor 0.0308 0.0676 0.1251
Loa Loa (eye worm) hypothetical protein 0.0142 0.0271 0.0551
Echinococcus granulosus carboxylesterase 5A 0.0336 0.0744 0.0813
Schistosoma mansoni jumonji/arid domain-containing protein 0.0132 0.0247 0.0285
Schistosoma mansoni two-pore calcium channel 0.0059 0.007 0.0079
Loa Loa (eye worm) hypothetical protein 0.0173 0.0346 0.0705
Leishmania major C-8 sterol isomerase-like protein 0.155 0.3694 0.3692
Schistosoma mansoni hypothetical protein 0.0111 0.0195 0.0224
Trypanosoma cruzi NADH dehydrogenase, putative 0.0316 0.0693 0.0691
Brugia malayi 6-phosphofructokinase 0.0109 0.019 0.0349
Brugia malayi Nuclear hormone receptor E75 0.0033 0.0007 0.0008
Onchocerca volvulus 0.011 0.0193 0.0633
Echinococcus granulosus hypothetical protein 0.0059 0.007 0.0077
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0059 0.0185
Plasmodium falciparum DNA gyrase subunit A 0.0078 0.0115 0.0301
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0111 0.0195 0.0213
Echinococcus multilocularis cpg binding protein 0.0061 0.0073 0.008
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0049 0.0045 0.0141
Onchocerca volvulus 0.0057 0.0064 0.0195
Echinococcus granulosus acetylcholinesterase 0.0336 0.0744 0.0813
Echinococcus granulosus allatostatin A receptor 0.0308 0.0676 0.0739
Onchocerca volvulus 0.0157 0.0307 0.1019
Loa Loa (eye worm) hypothetical protein 0.0075 0.011 0.0223
Schistosoma mansoni ATP-binding cassette transporter 0.0159 0.0313 0.0362
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0308 0.0676 0.0783
Brugia malayi bZIP transcription factor family protein 0.0436 0.0986 0.1828
Loa Loa (eye worm) hypothetical protein 0.0033 0.0007 0.0014
Onchocerca volvulus 0.0035 0.0013 0.0019
Loa Loa (eye worm) hypothetical protein 0.0308 0.0676 0.1376
Brugia malayi Protein kinase domain containing protein 0.0172 0.0345 0.0636
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0036 0.0013 0.0015
Loa Loa (eye worm) hypothetical protein 0.0033 0.0007 0.0014
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0113 0.02 0.0533
Chlamydia trachomatis DNA gyrase subunit A 0.0078 0.0115 0.035
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0113 0.02 0.0219
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0075 0.0109 0.0283
Brugia malayi EGF-like domain containing protein 0.0035 0.0013 0.0019
Onchocerca volvulus 0.0035 0.0013 0.0019
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0068 0.0092 0.0319
Schistosoma mansoni glutamate receptor NMDA 0.0258 0.0554 0.0642
Echinococcus granulosus tar DNA binding protein 0.0065 0.0084 0.0091
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0113 0.02 0.0219
Echinococcus multilocularis thioredoxin glutathione reductase 0.1577 0.376 0.411
Plasmodium falciparum heterochromatin protein 1 0.0036 0.0013 0.003
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.006 0.0071 0.0184
Brugia malayi Probable DNA topoisomerase II 0.0375 0.0838 0.1553
Loa Loa (eye worm) norepinephrine transporter 0.0664 0.1541 0.3136
Loa Loa (eye worm) hypothetical protein 0.0308 0.0676 0.1376
Loa Loa (eye worm) acetylcholinesterase 1 0.0336 0.0744 0.1515
Echinococcus multilocularis fmrfamide receptor 0.0308 0.0676 0.0739
Loa Loa (eye worm) carboxylesterase 0.0336 0.0744 0.1515
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0316 0.0693 0.1839
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0308 0.0676 0.0783
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0059 0.007 0.0077
Echinococcus granulosus ATP binding cassette sub family G 0.0031 0.0002 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0078 0.0115 0.0362
Echinococcus granulosus neuropeptides capa receptor 0.0308 0.0676 0.0739
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0043 0.003 0.0095
Echinococcus granulosus slit 2 protein 0.0035 0.0013 0.0014
Echinococcus granulosus dro:myosuppressin receptor 0.0308 0.0676 0.0739
Toxoplasma gondii isocitrate dehydrogenase 0.0031 0.0003 0.0007
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0034 0.001 0.0026
Trichomonas vaginalis glutaminase, putative 0.0278 0.0602 0.1892
Trichomonas vaginalis PIKK family atypical protein kinase 0.0107 0.0187 0.0586
Toxoplasma gondii LsmAD domain-containing protein 0.0106 0.0184 0.0491
Loa Loa (eye worm) hypothetical protein 0.0035 0.0013 0.0025
Brugia malayi Serotonin receptor 0.0308 0.0676 0.1251
Echinococcus multilocularis neuropeptide receptor 0.0308 0.0676 0.0739
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0316 0.0693 0.184
Schistosoma mansoni voltage-gated potassium channel 0.0059 0.007 0.0079
Echinococcus granulosus hyperpolarization activated cyclic 0.0075 0.0108 0.0118
Loa Loa (eye worm) Notch2 0.0035 0.0013 0.0025
Loa Loa (eye worm) hypothetical protein 0.0044 0.0034 0.007
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0598 0.1379 0.2559
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0335 0.0741 0.0739
Loa Loa (eye worm) hypothetical protein 0.007 0.0097 0.0198
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0068 0.0092 0.0238
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0068 0.0092 0.0238
Toxoplasma gondii hypothetical protein 0.0113 0.02 0.0533
Toxoplasma gondii NADPH-glutathione reductase 0.1189 0.2816 0.749
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0129 0.0241 0.049
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0308 0.0676 0.1251
Loa Loa (eye worm) hypothetical protein 0.0037 0.0017 0.0034
Echinococcus granulosus short transient receptor potential channel 6 0.006 0.0072 0.0078
Leishmania major hypothetical protein, conserved 0.0106 0.0184 0.0182
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0075 0.0109 0.0285
Schistosoma mansoni biogenic amine (5HT) receptor 0.0818 0.1914 0.2223
Toxoplasma gondii histone lysine methyltransferase SET1 0.0114 0.0204 0.0543
Trichomonas vaginalis DNA topoisomerase II, putative 0.0375 0.0838 0.2633
Onchocerca volvulus 0.0308 0.0676 0.2272
Loa Loa (eye worm) hypothetical protein 0.0034 0.001 0.002
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0316 0.0693 0.0691
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0013 0.0042
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0034 0.001 0.0008
Leishmania major protein kinase, putative 0.0058 0.0068 0.0066
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0436 0.0986 0.1078
Schistosoma mansoni chromobox protein 0.0151 0.0293 0.0338
Trichomonas vaginalis chromobox protein, putative 0.0036 0.0013 0.0042
Loa Loa (eye worm) hypothetical protein 0.0035 0.0013 0.0025
Leishmania major cytochrome p450-like protein 0.0087 0.0138 0.0136
Trypanosoma cruzi ferric reductase transmembrane protein, putative 0.0073 0.0104 0.0102
Brugia malayi Cytochrome P450 family protein 0.0113 0.0201 0.037
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0033 0.0007 0.0008
Trichomonas vaginalis chromobox protein, putative 0.0096 0.016 0.0504
Brugia malayi SET domain containing protein 0.0043 0.003 0.0052
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0308 0.0676 0.0783
Trichomonas vaginalis DNA helicase recq, putative 0.0046 0.0037 0.0117
Brugia malayi Dopamine receptor protein 1 0.0713 0.166 0.3082
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0013 0.0032
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0003 0.0003
Schistosoma mansoni amine GPCR 0.0308 0.0676 0.0783
Echinococcus multilocularis glutamate receptor 2 0.0159 0.0312 0.0341
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0308 0.0676 0.0739
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0115 0.0205 0.0203
Toxoplasma gondii Erv1 / Alr family protein 0.0109 0.0191 0.0507
Loa Loa (eye worm) hypothetical protein 0.0035 0.0013 0.0025
Loa Loa (eye worm) voltage-gated calcium channel 0.0059 0.007 0.0143
Brugia malayi Protein kinase domain containing protein 0.0048 0.0042 0.0073
Onchocerca volvulus 0.0308 0.0676 0.2272
Toxoplasma gondii hypothetical protein 0.0113 0.02 0.0533
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0041 0.0025 0.0023
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.0109 0.0191 0.0208
Loa Loa (eye worm) hypothetical protein 0.0036 0.0013 0.0027
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0316 0.0693 0.1841
Loa Loa (eye worm) hypothetical protein 0.0308 0.0676 0.1376
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0316 0.0693 0.2456
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0038 0.0018 0.0019
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0031 0.0003 0.0001
Entamoeba histolytica hypothetical protein 0.0073 0.0104 0.124
Echinococcus granulosus sodium and chloride dependent glycine 0.0113 0.02 0.0219
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0033 0.0007 0.0008
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0044 0.0033 0.0103
Echinococcus granulosus cyclin dependent kinase 0.0054 0.0057 0.0063
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.007 0.0097 0.0106
Schistosoma mansoni biogenic amine (5HT) receptor 0.1045 0.2466 0.2865
Trichomonas vaginalis xanthine dehydrogenase, putative 0.017 0.0338 0.1063
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxM_2 0.0057 0.0065 0.0225
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0308 0.0676 0.0739
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0316 0.0693 0.2266
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0129 0.0241 0.0239
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0349 0.0775 0.1437
Echinococcus multilocularis potassium voltage gated channel protein 0.0059 0.007 0.0077
Toxoplasma gondii aldehyde dehydrogenase 0.0195 0.04 0.1064
Onchocerca volvulus 0.0308 0.0676 0.2272
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0059 0.007 0.0079
Onchocerca volvulus 0.0057 0.0064 0.0195
Loa Loa (eye worm) hypothetical protein 0.0036 0.0013 0.0027
Echinococcus multilocularis dnaJ subfamily B 0.0816 0.191 0.2088
Leishmania major ATP-dependent phosphofructokinase 0.0108 0.0189 0.0187
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0308 0.0676 0.0783
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0316 0.0693 0.0758
Brugia malayi TAR-binding protein 0.0065 0.0084 0.0151
Loa Loa (eye worm) hypothetical protein 0.0308 0.0676 0.1376
Schistosoma mansoni chromobox protein 0.0036 0.0013 0.0013
Plasmodium vivax thioredoxin reductase, putative 0.1577 0.376 1
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0873 0.2049 0.3804
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0068 0.0092 0.009
Echinococcus granulosus tm gpcr rhodopsin 0.3793 0.9148 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0078 0.0115 0.0361
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0316 0.0693 0.1841
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0316 0.0693 0.0758
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0049 0.0045 0.0141
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0079 0.0119 0.013
Onchocerca volvulus 0.1244 0.2951 1
Brugia malayi jmjC domain containing protein 0.0034 0.001 0.0013
Echinococcus multilocularis g protein coupled receptor 0.0308 0.0676 0.0739
Loa Loa (eye worm) hypothetical protein 0.0052 0.0052 0.0105
Schistosoma mansoni voltage-gated potassium channel 0.0059 0.007 0.0079
Loa Loa (eye worm) hypothetical protein 0.0057 0.0064 0.0131
Schistosoma mansoni neuropeptide receptor 0.0308 0.0676 0.0783
Echinococcus granulosus PHD finger protein rhinoceros 0.0058 0.0067 0.0073
Echinococcus granulosus mitogen activated protein kinase 3 0.0153 0.0298 0.0326
Plasmodium falciparum glutathione reductase 0.1189 0.2816 0.7489
Schistosoma mansoni tyrosine kinase 0.0078 0.0115 0.0131
Brugia malayi RNA recognition motif domain containing protein 0.0065 0.0084 0.0151
Brugia malayi SRC-1 0.0038 0.0018 0.0028
Onchocerca volvulus 0.0035 0.0013 0.0019
Trichomonas vaginalis glucosylceramidase, putative 0.0879 0.2063 0.6482
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0316 0.0693 0.1908
Loa Loa (eye worm) hypothetical protein 0.0153 0.0298 0.0607
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0316 0.0693 0.1908
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0664 0.1541 0.1789
Echinococcus multilocularis neurogenic locus protein delta 0.0035 0.0013 0.0014
Onchocerca volvulus 0.0308 0.0676 0.2272
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0041 0.0025 0.0023
Loa Loa (eye worm) hypothetical protein 0.011 0.0193 0.0394
Loa Loa (eye worm) ion channel NompC 0.0059 0.007 0.0143
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.006 0.0071 0.0183
Loa Loa (eye worm) hypothetical protein 0.0033 0.0007 0.0014
Echinococcus multilocularis two pore calcium channel protein 2 0.0059 0.007 0.0077
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0308 0.0676 0.1376
Echinococcus multilocularis transfer RNA-Gly 0.0059 0.007 0.0077
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0316 0.0693 0.2179
Echinococcus granulosus glutamate synthase 0.0316 0.0693 0.0758
Loa Loa (eye worm) hypothetical protein 0.0308 0.0676 0.1376
Loa Loa (eye worm) hypothetical protein 0.011 0.0193 0.0394
Brugia malayi Calcium binding EGF domain containing protein 0.0035 0.0013 0.0019
Loa Loa (eye worm) hypothetical protein 0.0059 0.007 0.0143
Mycobacterium ulcerans flavoprotein disulfide reductase 0.1189 0.2816 1
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0308 0.0676 0.1376
Echinococcus granulosus protein jagged 1 0.0035 0.0013 0.0014
Schistosoma mansoni hypothetical protein 0.0036 0.0013 0.0013
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0153 0.0298 0.0793
Schistosoma mansoni neuropeptide F-like receptor 0.0308 0.0676 0.0783
Plasmodium falciparum DNA gyrase subunit B 0.014 0.0267 0.0706
Brugia malayi neuropeptide F receptor 0.0308 0.0676 0.1251
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0151 0.0293 0.032
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0068 0.0092 0.0319
Echinococcus multilocularis cyclin dependent kinase 0.0054 0.0057 0.0063
Brugia malayi Nuclear hormone receptor family member nhr-25 0.007 0.0097 0.0176
Plasmodium vivax glutathione reductase, putative 0.1577 0.376 1
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0048 0.0042 0.0046
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.1189 0.2816 0.749
Loa Loa (eye worm) hypothetical protein 0.0035 0.0013 0.0025
Onchocerca volvulus 0.0308 0.0676 0.2272
Echinococcus multilocularis voltage dependent calcium channel 0.0151 0.0293 0.032
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0248 0.053 0.0579
Onchocerca volvulus Neuropeptide F receptor homolog 0.0308 0.0676 0.2272
Loa Loa (eye worm) hypothetical protein 0.0113 0.02 0.0408
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0059 0.007 0.0077
Mycobacterium ulcerans carboxylesterase, LipT 0.0057 0.0064 0.0222
Schistosoma mansoni retinoic acid receptor RXR 0.007 0.0097 0.0111
Toxoplasma gondii selenide, water dikinase 0.0316 0.0693 0.1844
Loa Loa (eye worm) hypothetical protein 0.0035 0.0013 0.0025
Plasmodium falciparum transporter, putative 0.0113 0.02 0.0527
Trichomonas vaginalis PIKK family atypical protein kinase 0.0115 0.0205 0.0643
Echinococcus granulosus Polycystic kidney disease protein 0.0157 0.0307 0.0336
Echinococcus granulosus tyrosine protein kinase Fyn 0.0038 0.0018 0.0019
Loa Loa (eye worm) hypothetical protein 0.0308 0.0676 0.1376
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0153 0.0298 0.0296
Echinococcus granulosus glutamate receptor NMDA 0.0077 0.0114 0.0124
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0181 0.0366 0.04
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0113 0.02 0.023
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0048 0.0042 0.0046
Echinococcus multilocularis neuropeptides capa receptor 0.0308 0.0676 0.0739
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0068 0.0091 0.01
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0316 0.0693 0.2179
Loa Loa (eye worm) hypothetical protein 0.0308 0.0676 0.1376
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0075 0.0108 0.0219
Trypanosoma cruzi DNA topoisomerase II, putative 0.0368 0.082 0.0818
Trichomonas vaginalis PIKK family atypical protein kinase 0.0078 0.0115 0.0361
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0316 0.0693 0.0758
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0316 0.0693 0.1839
Loa Loa (eye worm) glutaminase 0.0278 0.0602 0.1226
Loa Loa (eye worm) hypothetical protein 0.0085 0.0134 0.0272
Echinococcus multilocularis ATP binding cassette sub family G 0.0031 0.0002 0.0002
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0151 0.0293 0.032
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0316 0.0693 0.0691
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0316 0.0693 0.1839
Entamoeba histolytica hypothetical protein 0.0036 0.0013 0.0159
Plasmodium vivax ataxin-2 like protein, putative 0.0106 0.0184 0.0487
Echinococcus granulosus inositol monophosphatase 1 0.0238 0.0505 0.0552
Toxoplasma gondii exonuclease III APE 0.006 0.0071 0.019
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0144 0.0276 0.0274
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0059 0.007 0.0126
Loa Loa (eye worm) RNA binding protein 0.0065 0.0084 0.0171
Brugia malayi Intermediate filament tail domain containing protein 0.0082 0.0125 0.0228
Loa Loa (eye worm) cytochrome P450 family protein 0.0113 0.0201 0.041
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0151 0.0293 0.032
Loa Loa (eye worm) TAR-binding protein 0.0065 0.0084 0.0171
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0068 0.0092 0.0238
Loa Loa (eye worm) programmed cell death 8 0.0316 0.0693 0.1412
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0144 0.0276 0.0274
Schistosoma mansoni voltage-gated potassium channel 0.0085 0.0134 0.0153
Echinococcus granulosus nuclear receptor 2DBD gamma 0.007 0.0097 0.0106
Loa Loa (eye worm) hypothetical protein 0.0308 0.0676 0.1376
Trichomonas vaginalis glucosylceramidase, putative 0.0879 0.2063 0.6482
Echinococcus granulosus voltage dependent calcium channel 0.0151 0.0293 0.032
Brugia malayi EGF-like domain containing protein 0.0035 0.0013 0.0019
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0039 0.0021 0.0022
Chlamydia trachomatis DNA gyrase subunit A 0.0078 0.0115 0.035
Entamoeba histolytica exodeoxyribonuclease III, putative 0.006 0.0071 0.0849
Echinococcus granulosus lipoxygenase domain containing protein 0.0157 0.0307 0.0336
Schistosoma mansoni voltage-gated potassium channel 0.0059 0.007 0.0079
Echinococcus granulosus lysine specific demethylase 6a 0.0034 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0308 0.0676 0.1376
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.0621 0.1952
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0113 0.02 0.023
Echinococcus multilocularis nmda type glutamate receptor 0.0183 0.037 0.0404
Schistosoma mansoni voltage-gated potassium channel 0.0075 0.0108 0.0123
Echinococcus granulosus glutamate NMDA receptor subunit 0.0321 0.0706 0.0771
Trypanosoma cruzi trypanothione reductase, putative 0.1189 0.2816 0.2815
Echinococcus granulosus ryanodine receptor 44f 0.0059 0.007 0.0077
Onchocerca volvulus 0.0057 0.0064 0.0195
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0195 0.04 0.1058
Loa Loa (eye worm) hypothetical protein 0.0308 0.0676 0.1376
Brugia malayi Protein kinase domain containing protein 0.0046 0.0039 0.0067
Echinococcus multilocularis aryl hydrocarbon receptor 0.0041 0.0025 0.0027
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0238 0.0505 0.1786
Echinococcus multilocularis Chromo domain 0.0036 0.0013 0.0015
Leishmania major hypothetical protein, conserved 0.0109 0.0191 0.0189
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0032 0.0005 0.001
Loa Loa (eye worm) glutaminase 2 0.0278 0.0602 0.1226
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0172 0.0345 0.0636
Echinococcus multilocularis isocitrate dehydrogenase 0.0031 0.0003 0.0003
Brugia malayi RE15519p 0.0308 0.0676 0.1251
Echinococcus granulosus potassium voltage gated channel protein 0.0059 0.007 0.0077
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0032 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0208 0.0432 0.0879
Echinococcus multilocularis netrin receptor unc 5 0.0048 0.0042 0.0046
Echinococcus granulosus neuropeptide Y receptor 0.0308 0.0676 0.0739
Schistosoma mansoni cellular tumor antigen P53 0.0107 0.0187 0.0215
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.007 0.0097 0.0198
Echinococcus granulosus calcium activated potassium channel 0.0062 0.0076 0.0083
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0375 0.0838 0.0916
Brugia malayi nuclear hormone receptor family member odr-7 0.0033 0.0007 0.0008
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0068 0.0092 0.0319
Loa Loa (eye worm) hypothetical protein 0.0308 0.0676 0.1376
Loa Loa (eye worm) hypothetical protein 0.0151 0.0293 0.0596
Brugia malayi hypothetical protein 0.0069 0.0093 0.0168
Echinococcus granulosus biogenic amine 5HT receptor 0.1045 0.2466 0.2696
Onchocerca volvulus 0.0057 0.0064 0.0195
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0043 0.0031 0.0029
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.006 0.0071 0.0069
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0068 0.0092 0.0238
Schistosoma mansoni RAR-like nuclear receptor 0.007 0.0097 0.0111
Schistosoma mansoni chromobox protein 0.0036 0.0013 0.0013
Entamoeba histolytica DNA topoisomerase II, putative 0.0375 0.0838 1
Brugia malayi larval opioid receptor 0.0308 0.0676 0.1251
Schistosoma mansoni hypothetical protein 0.0111 0.0195 0.0224
Echinococcus multilocularis cyclin dependent kinase 1 0.0054 0.0057 0.0063
Trypanosoma brucei DNA topoisomerase ii 0.0335 0.0741 0.0739
Loa Loa (eye worm) DR-78 0.0033 0.0007 0.0014
Echinococcus granulosus neurogenic locus notch protein 0.0035 0.0013 0.0014
Trypanosoma cruzi DNA topoisomerase II, putative 0.0368 0.082 0.0818
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0013 0.0042
Giardia lamblia High cysteine protein 0.0035 0.0013 0.0041
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0316 0.0693 0.2266
Schistosoma mansoni glutamate receptor AMPA 0.0159 0.0312 0.036
Plasmodium vivax FAD-linked sulfhydryl oxidase ERV1, putative 0.0109 0.0191 0.0504
Brugia malayi Protein cec-1. 0.0036 0.0013 0.002
Onchocerca volvulus 0.0082 0.0125 0.0402
Schistosoma mansoni adenoreceptor 0.0308 0.0676 0.0783
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0113 0.02 0.023
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.3793 0.9148 1
Loa Loa (eye worm) hypothetical protein 0.0033 0.0007 0.0014
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0059 0.007 0.0077
Loa Loa (eye worm) hypothetical protein 0.0038 0.0019 0.0038
Echinococcus granulosus rhodopsin orphan GPCR 0.0308 0.0676 0.0739
Loa Loa (eye worm) hypothetical protein 0.0137 0.026 0.0529
Echinococcus multilocularis voltage gated potassium channel 0.0059 0.007 0.0077
Brugia malayi hypothetical protein 0.0308 0.0676 0.1251
Mycobacterium ulcerans carbon monoxyde dehydrogenase medium chain CoxM 0.0057 0.0065 0.0225
Schistosoma mansoni neuropeptide F-like receptor 0.0308 0.0676 0.0783
Schistosoma mansoni jumonji/arid domain-containing protein 0.0132 0.0247 0.0285
Echinococcus granulosus phd:f box containing protein 0.0034 0.001 0.001
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0127 0.0236 0.0272
Trichomonas vaginalis PIKK family atypical protein kinase 0.0078 0.0115 0.0362
Trichomonas vaginalis mercuric reductase, putative 0.1189 0.2816 0.8849
Loa Loa (eye worm) hypothetical protein 0.0818 0.1914 0.3897
Loa Loa (eye worm) intermediate filament protein 0.0082 0.0125 0.0255
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0308 0.0676 0.2272
Trypanosoma cruzi ERV/ALR sulfhydryl oxidase domain-containing protein 0.0109 0.0191 0.0189
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.1189 0.2816 1
Echinococcus multilocularis G protein coupled receptor 139 0.0308 0.0676 0.0739
Mycobacterium leprae putative cytochrome p450 0.0068 0.0092 0.0222
Trichomonas vaginalis glucosylceramidase, putative 0.0879 0.2063 0.6482
Loa Loa (eye worm) hypothetical protein 0.0041 0.0025 0.005
Plasmodium vivax DNA gyrase subunit B, putative 0.014 0.0267 0.0708
Mycobacterium ulcerans dehydrogenase 0.0316 0.0693 0.2456
Echinococcus granulosus rhodopsin orphan GPCR 0.0308 0.0676 0.0739
Toxoplasma gondii transporter, cation channel family protein 0.0059 0.007 0.0186
Treponema pallidum NADH oxidase 0.1189 0.2816 1
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0057 0.0064 0.007
Loa Loa (eye worm) hypothetical protein 0.0059 0.007 0.0143
Brugia malayi nuclear receptor NHR-67 0.0033 0.0007 0.0008
Entamoeba histolytica hypothetical protein 0.0036 0.0013 0.0159
Brugia malayi Associated with TFs and helicases family protein 0.0036 0.0013 0.002
Schistosoma mansoni serine/threonine protein kinase 0.0153 0.0298 0.0345
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0316 0.0693 0.0758
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0048 0.0044 0.0048
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0068 0.0092 0.009
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0057 0.018
Toxoplasma gondii transporter, cation channel family protein 0.0077 0.0112 0.0298
Schistosoma mansoni hypothetical protein 0.0308 0.0676 0.0783
Loa Loa (eye worm) runx1 0.0065 0.0084 0.0172
Trypanosoma cruzi NADH dehydrogenase, putative 0.0316 0.0693 0.0691
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.002 0.0063
Loa Loa (eye worm) hypothetical protein 0.0519 0.1187 0.2417
Brugia malayi Delta serrate ligand family protein 0.0035 0.0013 0.0019
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0248 0.053 0.0579
Loa Loa (eye worm) hypothetical protein 0.0157 0.0307 0.0625
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.014 0.0267 0.0893
Loa Loa (eye worm) hypothetical protein 0.0059 0.007 0.0143
Schistosoma mansoni loxhd1 0.0157 0.0307 0.0355
Loa Loa (eye worm) hypothetical protein 0.0113 0.02 0.0408
Echinococcus granulosus Chromobox protein 3 0.0036 0.0013 0.0015
Trichomonas vaginalis DNA helicase recq1, putative 0.0046 0.0037 0.0117
Loa Loa (eye worm) hypothetical protein 0.007 0.0097 0.0198
Echinococcus granulosus rhodopsin orphan GPCR 0.0308 0.0676 0.0739
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0068 0.0092 0.009
Onchocerca volvulus 0.0141 0.0269 0.0891
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0308 0.0676 0.0739
Echinococcus multilocularis L aminoadipate semialdehyde 0.0081 0.0124 0.0135
Onchocerca volvulus 0.0057 0.0066 0.0199
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0105 0.0182 0.0199
Echinococcus granulosus tm gpcr rhodopsin 0.0308 0.0676 0.0739
Leishmania major cytochrome p450-like protein 0.0068 0.0092 0.009
Schistosoma mansoni thyroid hormone receptor 0.007 0.0097 0.0111
Loa Loa (eye worm) TK protein kinase 0.0034 0.0009 0.0018
Giardia lamblia DNA topoisomerase II 0.0356 0.0792 0.2811
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0065 0.0084 0.0171
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0308 0.0676 0.0739
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0038 0.0018 0.0019
Echinococcus granulosus tyrosine protein kinase Lyn 0.004 0.0024 0.0026
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0036 0.0013 0.0013
Schistosoma mansoni glutamate synthase 0.0316 0.0693 0.0804
Wolbachia endosymbiont of Brugia malayi DNA gyrase subunit A 0.0078 0.0115 0.016
Echinococcus granulosus chromobox protein 1 0.0151 0.0293 0.032
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.007 0.0097 0.0198
Brugia malayi CHD4 protein 0.0039 0.0021 0.0035
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0036 0.0013 0.0159
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.006 0.0071 0.0145
Loa Loa (eye worm) carboxylesterase 0.0057 0.0064 0.0131
Onchocerca volvulus Slit protein homolog 0.0035 0.0013 0.0019
Schistosoma mansoni thyroid hormone receptor 0.007 0.0097 0.0111
Schistosoma mansoni hypothetical protein 0.0239 0.0507 0.0587
Echinococcus multilocularis slit 2 protein 0.0035 0.0013 0.0014
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0169 0.0336 0.0684
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0308 0.0676 0.0783
Loa Loa (eye worm) hypothetical protein 0.0308 0.0676 0.1376
Brugia malayi Calcium binding EGF domain containing protein 0.0035 0.0013 0.0019
Mycobacterium tuberculosis Putative ferredoxin reductase 0.063 0.1458 0.3874
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.3059 0.7362 0.7362
Echinococcus multilocularis jumonji domain containing protein 0.0081 0.0122 0.0134
Onchocerca volvulus Putative cubilin 0.0035 0.0013 0.0019
Schistosoma mansoni hypothetical protein 0.0035 0.0013 0.0012
Schistosoma mansoni tyrosine kinase 0.0079 0.0119 0.0136
Trypanosoma cruzi cdc2-related kinase 1 0.0054 0.0057 0.0055
Loa Loa (eye worm) hypothetical protein 0.0059 0.007 0.0143
Mycobacterium ulcerans putative regulatory protein 0.0115 0.0207 0.0728
Loa Loa (eye worm) hypothetical protein 0.0059 0.007 0.0143
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0582 0.1341 0.2729
Brugia malayi Nuclear hormone receptor family member nhr-1 0.007 0.0097 0.0176
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0084 0.0095
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0084 0.0095
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0044 0.0033 0.0036
Echinococcus multilocularis potassium voltage gated channel protein 0.0059 0.007 0.0077
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0034 0.001 0.0008
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0129 0.0241 0.0239
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0129 0.0241 0.0443
Echinococcus granulosus protein jagged 2 0.0035 0.0013 0.0014
Echinococcus granulosus Nuclear hormone receptor HR96 0.0033 0.0007 0.0008
Schistosoma mansoni sulfide quinone reductase 0.0316 0.0693 0.0804
Brugia malayi hypothetical protein 0.0308 0.0676 0.1251
Schistosoma mansoni sodium-dependent amino acid transporter 0.0113 0.02 0.023
Mycobacterium ulcerans endonuclease IV 0.0075 0.0109 0.0378
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0036 0.0013 0.0036
Trichomonas vaginalis glutamate synthase, putative 0.0316 0.0693 0.2179
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0316 0.0693 0.0758
Schistosoma mansoni tyrosine kinase 0.0078 0.0115 0.0131
Echinococcus multilocularis glutamate receptor NMDA 0.0077 0.0114 0.0124
Echinococcus granulosus JmjC domain containing protein 4 0.0034 0.001 0.001
Onchocerca volvulus 0.0308 0.0676 0.2272
Echinococcus multilocularis inositol monophosphatase 1 0.0238 0.0505 0.0552
Chlamydia trachomatis thioredoxin reductase 0.0316 0.0693 0.2415
Trypanosoma cruzi PAB1-binding protein , putative 0.0106 0.0184 0.0182
Echinococcus granulosus lysine specific demethylase 5A 0.0132 0.0247 0.027
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0316 0.0693 0.2456
Brugia malayi nuclear receptor NHR-88 0.0033 0.0007 0.0008
Echinococcus granulosus nuclear receptor nhr 48 0.0033 0.0007 0.0008
Schistosoma mansoni retinoid-x-receptor (RXR) 0.007 0.0097 0.0111
Echinococcus multilocularis nmda type glutamate receptor 0.01 0.0168 0.0184
Echinococcus multilocularis 0.0045 0.0036 0.0039
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0158 0.031 0.0339
Loa Loa (eye worm) hypothetical protein 0.011 0.0193 0.0394
Loa Loa (eye worm) hypothetical protein 0.0158 0.031 0.0631
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0044 0.0033 0.0103
Loa Loa (eye worm) hypothetical protein 0.0113 0.02 0.0408
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0181 0.0365 0.0399
Echinococcus multilocularis neuropeptides capa receptor 0.0308 0.0676 0.0739
Schistosoma mansoni serine/threonine protein kinase 0.0054 0.0057 0.0064
Echinococcus multilocularis sodium and chloride dependent glycine 0.0113 0.02 0.0219
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0213 0.0444 0.1175
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0308 0.0676 0.0739
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0068 0.0092 0.0238
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0316 0.0693 0.2179
Brugia malayi notch-like transmembrane receptor 0.0035 0.0013 0.0019
Echinococcus granulosus short transient receptor potential channel 6 0.0059 0.007 0.0077
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0059 0.007 0.0126
Echinococcus multilocularis hyperpolarization activated cyclic 0.0075 0.0108 0.0118
Echinococcus granulosus cyclin dependent kinase 1 0.0054 0.0057 0.0063
Mycobacterium ulcerans aldehyde dehydrogenase 0.0195 0.04 0.1415
Loa Loa (eye worm) hypothetical protein 0.0035 0.0013 0.0025
Brugia malayi Carboxylesterase family protein 0.0057 0.0064 0.0115
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0308 0.0676 0.0783
Brugia malayi Pre-SET motif family protein 0.0158 0.031 0.0571
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0194 0.0397 0.0459
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0059 0.007 0.0079
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0075 0.0108 0.0123
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0308 0.0676 0.0739
Brugia malayi Nuclear hormone receptor family member nhr-3 0.007 0.0097 0.0176
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0316 0.0693 0.0691
Echinococcus granulosus tyrosine protein kinase Fyn 0.0038 0.0018 0.0019
Onchocerca volvulus 0.0308 0.0676 0.2272
Echinococcus multilocularis acetylcholinesterase 0.0336 0.0744 0.0813
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0105 0.0182 0.0199
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0057 0.018
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0068 0.0092 0.0319
Brugia malayi nuclear receptor RXR 0.0037 0.0017 0.0026
Toxoplasma gondii target of rapamycin (TOR), putative 0.0107 0.0187 0.0496
Brugia malayi photoreceptor-specific nuclear receptor 0.007 0.0097 0.0176
Schistosoma mansoni alpha-1 adrenergic receptor 0.0308 0.0676 0.0783
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0144 0.0276 0.0274
Brugia malayi M-phase phosphoprotein, mpp8 0.0141 0.0269 0.0496
Loa Loa (eye worm) SRC-1 0.0038 0.0018 0.0036
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0321 0.0706 0.0771
Entamoeba histolytica ABC transporter, putative 0.0031 0.0002 0.0024
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0308 0.0676 0.1376
Loa Loa (eye worm) hypothetical protein 0.0106 0.0184 0.0375
Loa Loa (eye worm) neuropeptide F receptor 0.0308 0.0676 0.1376
Loa Loa (eye worm) transcription factor SMAD2 0.0238 0.0505 0.1029
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0059 0.007 0.0079
Loa Loa (eye worm) DnaJ domain-containing protein 0.0062 0.0076 0.0156
Brugia malayi conserved hypotetical protein 0.0033 0.0007 0.0008
Loa Loa (eye worm) hypothetical protein 0.0035 0.0013 0.0025
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0036 0.0013 0.003
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.0189 0.0595
Echinococcus multilocularis lysine specific demethylase 5A 0.0129 0.0239 0.0261
Echinococcus multilocularis JmjC domain containing protein 4 0.0034 0.001 0.001
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0308 0.0676 0.0783
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0308 0.0676 0.0739
Loa Loa (eye worm) hypothetical protein 0.0035 0.0013 0.0025
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0151 0.0293 0.032
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0038 0.0018 0.0019
Trichomonas vaginalis PIKK family atypical protein kinase 0.0093 0.0154 0.0482
Schistosoma mansoni rab6-interacting 0.0157 0.0307 0.0355
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0037 0.0017 0.0018
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.006 0.0072 0.007
Schistosoma mansoni hypothetical protein 0.0907 0.2131 0.2476
Leishmania major phosphatidylinositol 3-kinase, putative 0.0048 0.0044 0.0042
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0059 0.007 0.0077
Echinococcus multilocularis two pore calcium channel protein 1 0.0059 0.007 0.0077
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0316 0.0693 0.0758
Echinococcus granulosus fibropellin Ia 0.0035 0.0013 0.0014
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxL_2 0.008 0.0121 0.0421
Trichomonas vaginalis chromobox protein, putative 0.0151 0.0293 0.0921
Brugia malayi hypothetical protein 0.0982 0.2315 0.4297
Echinococcus granulosus voltage gated potassium channel 0.0085 0.0134 0.0146
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.0621 0.1952
Echinococcus granulosus hyperpolarization activated cyclic 0.0075 0.0108 0.0118
Schistosoma mansoni protein phosphatase 2C 0.0034 0.001 0.0009
Echinococcus multilocularis protein jagged 2 0.0035 0.0013 0.0014
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0059 0.007 0.0079
Echinococcus granulosus thyroid hormone receptor alpha 0.0033 0.0007 0.0008
Brugia malayi protein-tyrosine kinase 0.0034 0.0009 0.0012
Onchocerca volvulus 0.0113 0.02 0.0656
Plasmodium vivax ABC transporter G family member 2, putative 0.0031 0.0002 0.0002
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (medium chain) 0.0057 0.0065 0.0167
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.007 0.0097 0.0198
Loa Loa (eye worm) hypothetical protein 0.0308 0.0676 0.1376
Trypanosoma cruzi cytochrome P450, putative 0.0087 0.0138 0.0136
Onchocerca volvulus 0.011 0.0193 0.0633
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0025 0.0078
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0129 0.0241 0.0263
Echinococcus granulosus ATP binding cassette sub family G 0.0031 0.0002 0.0002
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0153 0.0298 0.0296
Echinococcus granulosus voltage dependent calcium channel 0.0077 0.0112 0.0123
Echinococcus granulosus ecdysone induced protein 78C 0.007 0.0097 0.0106
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.014 0.0266 0.0937
Brugia malayi Nuclear hormone receptor-like 1 0.007 0.0097 0.0176
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0316 0.0693 0.8273
Echinococcus granulosus potassium voltage gated channel protein 0.0059 0.007 0.0077
Echinococcus multilocularis sex peptide receptor 0.0308 0.0676 0.0739
Onchocerca volvulus Glucosylceramidase homolog 0.0879 0.2063 0.6983
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0048 0.0044 0.0048
Loa Loa (eye worm) carboxylesterase 0.0057 0.0064 0.0131
Brugia malayi Animal haem peroxidase family protein 0.011 0.0193 0.0355
Loa Loa (eye worm) hypothetical protein 0.0059 0.007 0.0143
Echinococcus multilocularis neurogenic locus protein delta 0.0035 0.0013 0.0014
Trichomonas vaginalis chromobox protein, putative 0.0036 0.0013 0.0042
Echinococcus granulosus neuropeptide Y receptor 0.0308 0.0676 0.0739
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0181 0.0365 0.1291
Schistosoma mansoni peroxidasin 0.0114 0.0203 0.0233
Brugia malayi Muscle positioning protein 4 0.0035 0.0013 0.0019
Loa Loa (eye worm) TK/INSR protein kinase 0.0048 0.0042 0.0086
Schistosoma mansoni notch 0.0035 0.0013 0.0012
Loa Loa (eye worm) hypothetical protein 0.0308 0.0676 0.1376
Leishmania major NADH dehydrogenase, putative 0.0316 0.0693 0.0691
Treponema pallidum DNA gyrase, subunit A (gyrA) 0.0078 0.0115 0.035
Trichomonas vaginalis PIKK family atypical protein kinase 0.0107 0.0187 0.0586
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.006 0.0071 0.0246
Schistosoma mansoni Tr4/Tr2 (homologue) 0.007 0.0097 0.0111
Echinococcus multilocularis potassium large conductance calcium activated 0.0059 0.007 0.0077
Schistosoma mansoni lamin 0.0082 0.0125 0.0143
Trypanosoma cruzi hypothetical protein, conserved 0.0316 0.0693 0.0691
Schistosoma mansoni voltage-gated potassium channel 0.0059 0.007 0.0079
Trichomonas vaginalis PIKK family atypical protein kinase 0.0115 0.0205 0.0643
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0316 0.0693 0.0758
Mycobacterium tuberculosis Probable oxidoreductase 0.1503 0.3581 0.9524
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0068 0.0091 0.01
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0043 0.0031 0.0029
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0286 0.0621 0.7414
Brugia malayi jmjC domain containing protein 0.0132 0.0247 0.0454
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0068 0.0092 0.0238
Trichomonas vaginalis PIKK family atypical protein kinase 0.0086 0.0135 0.0426
Loa Loa (eye worm) hypothetical protein 0.0308 0.0676 0.1376
Onchocerca volvulus 0.0076 0.0112 0.0355
Echinococcus granulosus lipoxygenase domain containing protein 0.0157 0.0307 0.0336
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0114 0.0203 0.0201
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.006 0.0071 0.025
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0153 0.0298 0.0607
Brugia malayi CXXC zinc finger family protein 0.0057 0.0066 0.0117
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.1189 0.2816 1
Echinococcus multilocularis protein jagged 1 0.0035 0.0013 0.0014
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.014 0.0267 0.0714
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0598 0.1379 0.1601
Schistosoma mansoni amine GPCR 0.0308 0.0676 0.0783
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0068 0.0091 0.01
Plasmodium falciparum LCCL domain-containing protein 0.0157 0.0307 0.0812
Mycobacterium tuberculosis Probable reductase 0.063 0.1458 0.3874
Onchocerca volvulus 0.0308 0.0676 0.2272
Schistosoma mansoni opsin-like receptor 0.0308 0.0676 0.0783
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0316 0.0693 0.1412
Echinococcus multilocularis G-protein coupled receptor, putative 0.0308 0.0676 0.0739
Schistosoma mansoni transient receptor potential channel 0.0059 0.007 0.0079
Loa Loa (eye worm) hypothetical protein 0.0057 0.0064 0.0131
Echinococcus granulosus nuclear factor of activated T cells 5 0.0225 0.0472 0.0516
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.0013 0.0042
Echinococcus multilocularis rhodopsin orphan GPCR 0.0308 0.0676 0.0739
Trypanosoma cruzi hypothetical protein, conserved 0.0316 0.0693 0.0691
Plasmodium falciparum DNA topoisomerase 2 0.0375 0.0838 0.2225
Echinococcus granulosus jumonji domain containing protein 0.0081 0.0122 0.0134
Echinococcus granulosus L aminoadipate semialdehyde 0.0081 0.0124 0.0135
Trichomonas vaginalis PIKK family atypical protein kinase 0.0107 0.0187 0.0586
Trypanosoma brucei cytochrome P450, putative 0.0087 0.0138 0.0136
Trichomonas vaginalis CMGC family protein kinase 0.0153 0.0298 0.0937
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.0621 0.1952
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0059 0.007 0.0126
Onchocerca volvulus Peroxidase homolog 0.011 0.0193 0.0633
Brugia malayi cation channel family protein 0.0059 0.007 0.0126
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.1189 0.2816 0.2815
Echinococcus multilocularis thyroid hormone receptor alpha 0.007 0.0097 0.0106
Echinococcus granulosus alpha 1A adrenergic receptor 0.0308 0.0676 0.0739
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0375 0.0838 0.1553
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0093 0.0152 0.0277
Schistosoma mansoni serine/threonine protein kinase 0.0172 0.0345 0.0398
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0093 0.0152 0.0166
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0308 0.0676 0.0783
Echinococcus multilocularis transient receptor potential cation channel 0.0059 0.007 0.0077
Echinococcus granulosus sodium channel protein 0.0676 0.1569 0.1715
Onchocerca volvulus 0.0113 0.02 0.0656
Mycobacterium ulcerans glutamate synthase subunit beta 0.0316 0.0693 0.2456
Schistosoma mansoni cell polarity protein 0.0035 0.0013 0.0012
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0044 0.0033 0.0103
Giardia lamblia NADH oxidase lateral transfer candidate 0.1189 0.2816 1
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0068 0.0092 0.009
Echinococcus granulosus serotonin receptor 0.0308 0.0676 0.0739
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0059 0.007 0.0077
Schistosoma mansoni lipoxygenase 0.0624 0.1443 0.1676
Loa Loa (eye worm) hypothetical protein 0.0336 0.0744 0.1515
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0238 0.0505 0.0503
Echinococcus granulosus para nitrobenzyl esterase 0.0057 0.0064 0.007
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0038 0.0018 0.0019
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0075 0.0108 0.0123
Schistosoma mansoni lozenge 0.0065 0.0084 0.0096
Entamoeba histolytica hypothetical protein 0.0036 0.0013 0.0159
Loa Loa (eye worm) hypothetical protein 0.0336 0.0744 0.1515
Plasmodium falciparum glutathione reductase 0.1577 0.376 1
Loa Loa (eye worm) hypothetical protein 0.0075 0.011 0.0223
Echinococcus multilocularis peroxidasin 0.0114 0.0203 0.0221
Brugia malayi Bromodomain containing protein 0.0058 0.0067 0.012
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0059 0.007 0.0126
Echinococcus granulosus serotonin transporter 0.0664 0.1541 0.1684
Loa Loa (eye worm) TOPoisomerase family member 0.0375 0.0838 0.1706
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0153 0.0298 0.0296
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.0189 0.2258
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0316 0.0693 0.2456
Echinococcus granulosus neurogenic locus notch protein 0.0035 0.0013 0.0014
Echinococcus multilocularis neuropeptide s receptor 0.1753 0.4188 0.4578
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0113 0.02 0.0408
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0316 0.0693 0.2456
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0038 0.0018 0.0019
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.007 0.0097 0.0106
Loa Loa (eye worm) notch protein 0.0035 0.0013 0.0025
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0041 0.0025 0.0023
Echinococcus multilocularis RUN 0.0157 0.0307 0.0336
Loa Loa (eye worm) hypothetical protein 0.0035 0.0013 0.0025
Loa Loa (eye worm) hypothetical protein 0.0038 0.0019 0.0038
Loa Loa (eye worm) hypothetical protein 0.0036 0.0013 0.0027
Brugia malayi hypothetical protein 0.0113 0.02 0.0367
Leishmania major acetoin dehydrogenase e3 component-like protein 0.3059 0.7362 0.7362
Loa Loa (eye worm) hypothetical protein 0.0082 0.0125 0.0255
Loa Loa (eye worm) hypothetical protein 0.011 0.0193 0.0394
Loa Loa (eye worm) hypothetical protein 0.0035 0.0013 0.0025
Onchocerca volvulus 0.0059 0.007 0.0214
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0873 0.2049 0.3804
Echinococcus multilocularis nuclear receptor nhr 48 0.0033 0.0007 0.0008
Echinococcus multilocularis transient receptor potential cation channel 0.006 0.0072 0.0078
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0258 0.0553 0.1855
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0169 0.0336 0.0367
Schistosoma mansoni glutamate receptor AMPA 0.0159 0.0312 0.036
Trichomonas vaginalis PIKK family atypical protein kinase 0.0085 0.0133 0.0419
Brugia malayi hypothetical protein 0.0308 0.0676 0.1251
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.007 0.0097 0.0106
Brugia malayi Thioredoxin reductase 0.1577 0.376 0.6984
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0195 0.04 0.0437
Echinococcus multilocularis conserved hypothetical protein 0.2904 0.6986 0.7637
Loa Loa (eye worm) jmjC domain-containing protein 0.0132 0.0247 0.0503
Loa Loa (eye worm) hypothetical protein 0.0059 0.007 0.0143
Trichomonas vaginalis glucosylceramidase, putative 0.1339 0.3183 1
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.1503 0.3581 0.9524
Echinococcus granulosus tm gpcr rhodopsin 0.0815 0.1907 0.2084
Trichomonas vaginalis Heterochromatin protein, putative 0.0036 0.0013 0.0042
Schistosoma mansoni hypothetical protein 0.0048 0.0042 0.0046
Brugia malayi hypothetical protein 0.011 0.0193 0.0355
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0664 0.1541 0.2859
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0041 0.0025 0.005
Brugia malayi Nuclear hormone receptor family member nhr-19 0.007 0.0097 0.0176
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0316 0.0693 0.1839
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.007 0.0097 0.0106
Schistosoma mansoni biogenic amine receptor 0.0308 0.0676 0.0783
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0316 0.0693 0.0691
Loa Loa (eye worm) glutamate receptor 2 0.0159 0.0312 0.0635
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0151 0.0293 0.054
Onchocerca volvulus 0.0308 0.0676 0.2272
Onchocerca volvulus 0.02 0.0413 0.138
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0115 0.0205 0.0203
Schistosoma mansoni DNA topoisomerase II 0.0375 0.0838 0.0972
Loa Loa (eye worm) hypothetical protein 0.0113 0.02 0.0408
Trichomonas vaginalis guanylate cyclase, putative 0.0044 0.0033 0.0103
Toxoplasma gondii Erv1 / Alr family protein 0.0109 0.0191 0.0507
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0153 0.0298 0.0296
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0144 0.0276 0.3297
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0375 0.0838 0.0916
Loa Loa (eye worm) nuclear hormone receptor 0.0033 0.0007 0.0014
Echinococcus multilocularis neurogenic locus notch protein 0.0035 0.0013 0.0014
Echinococcus multilocularis lipoxygenase domain containing protein 0.0157 0.0307 0.0336
Loa Loa (eye worm) hypothetical protein 0.007 0.0097 0.0198
Echinococcus granulosus nmda type glutamate receptor 0.0183 0.037 0.0404
Brugia malayi Nuclear hormone receptor family member nhr-40 0.007 0.0097 0.0176
Loa Loa (eye worm) voltage-gated potassium channel 0.0059 0.007 0.0143
Echinococcus multilocularis lipoxygenase domain containing protein 0.0157 0.0307 0.0336
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0158 0.031 0.0358
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0036 0.0013 0.0159
Leishmania major mitochondrial DNA topoisomerase II 0.0335 0.0741 0.0739
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0036 0.0013 0.0036
Loa Loa (eye worm) hypothetical protein 0.0113 0.02 0.0408
Mycobacterium ulcerans hypothetical protein 0.0316 0.0693 0.2456
Brugia malayi Tachykinin-like peptides receptor 99D 0.0308 0.0676 0.1251
Echinococcus granulosus bloom syndrome protein 0.0046 0.0037 0.004
Echinococcus multilocularis lamin dm0 0.0082 0.0125 0.0137
Loa Loa (eye worm) hypothetical protein 0.0308 0.0676 0.1376
Loa Loa (eye worm) hypothetical protein 0.0308 0.0676 0.1376
Brugia malayi Nuclear hormone receptor-like 1 0.0037 0.0017 0.0026
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0316 0.0693 0.1284
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0308 0.0676 0.0739
Plasmodium vivax multidomain scavenger receptor, putative 0.0157 0.0307 0.0814
Leishmania major hypothetical protein, conserved 0.0316 0.0693 0.0691
Onchocerca volvulus Peroxidasin homolog 0.011 0.0193 0.0633
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0144 0.0276 0.0302
Echinococcus multilocularis Chromobox protein 3 0.0036 0.0013 0.0015
Onchocerca volvulus 0.0194 0.0397 0.1325
Schistosoma mansoni notch 0.0036 0.0014 0.0014
Plasmodium falciparum thioredoxin reductase 0.1189 0.2816 0.7489
Brugia malayi F/Y-rich N-terminus family protein 0.0042 0.0029 0.0049
Loa Loa (eye worm) hypothetical protein 0.0035 0.0013 0.0025
Schistosoma mansoni hypothetical protein 0.0907 0.2131 0.2476
Loa Loa (eye worm) hypothetical protein 0.0308 0.0676 0.1376
Plasmodium vivax JmjC domain containing protein 0.0034 0.001 0.0022
Schistosoma mansoni hypothetical protein 0.0068 0.0091 0.0104
Echinococcus granulosus transient receptor potential gamma protein 0.0059 0.007 0.0077
Echinococcus granulosus transient receptor potential cation channel 0.0059 0.007 0.0077
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0335 0.0741 0.0739
Wolbachia endosymbiont of Brugia malayi NADPH-dependent glutamate synthase beta chain 0.0316 0.0693 0.2266
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0059 0.007 0.0126
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0181 0.0366 0.04
Leishmania major DNA topoisomerase ii 0.0368 0.082 0.0818
Schistosoma mansoni sodium/chloride dependent transporter 0.0115 0.0206 0.0237
Mycobacterium ulcerans DNA gyrase subunit B 0.014 0.0267 0.0942
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.1189 0.2816 0.7489
Loa Loa (eye worm) hypothetical protein 0.0115 0.0206 0.0419
Toxoplasma gondii transporter, cation channel family protein 0.0059 0.007 0.0186
Schistosoma mansoni voltage-gated potassium channel 0.0179 0.0362 0.0419
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0109 0.0191 0.0189
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.007 0.0097 0.0176
Echinococcus granulosus survival motor neuron protein 1 0.0982 0.2315 0.253
Schistosoma mansoni tyrosine kinase 0.0048 0.0042 0.0047
Plasmodium falciparum ataxin-2 like protein, putative 0.0106 0.0184 0.0485
Brugia malayi PHD-finger family protein 0.0058 0.0067 0.012
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0316 0.0693 0.8273
Echinococcus granulosus epidermal growth factor receptor 0.0079 0.0119 0.013
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0308 0.0676 0.0739
Loa Loa (eye worm) cytochrome P450 family protein 0.0087 0.0138 0.0281
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0041 0.0025 0.0027
Trichomonas vaginalis ap endonuclease, putative 0.006 0.0071 0.0224
Brugia malayi nuclear hormone receptor family member nhr-6 0.0033 0.0007 0.0008
Schistosoma mansoni amine GPCR 0.2233 0.5355 0.6224
Echinococcus multilocularis mitogen activated protein kinase 3 0.0153 0.0298 0.0326
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0068 0.0092 0.0319
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0084 0.0095
Loa Loa (eye worm) serotonin transporter b 0.0664 0.1541 0.3136
Trichomonas vaginalis PIKK family atypical protein kinase 0.0144 0.0276 0.0868
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0068 0.0092 0.0238
Schistosoma mansoni tyrosine kinase 0.0048 0.0042 0.0047
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0181 0.0365 0.0363
Onchocerca volvulus Chorion peroxidase homolog 0.011 0.0193 0.0633
Brugia malayi G-protein coupled receptor 0.0308 0.0676 0.1251
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0113 0.02 0.0219
Loa Loa (eye worm) animal heme peroxidase 0.011 0.0193 0.0394
Trypanosoma brucei ferric reductase transmembrane protein, putative 0.0073 0.0104 0.0102
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0129 0.0241 0.0278
Brugia malayi Dopamine receptor protein 2 0.0308 0.0676 0.1251
Brugia malayi Serotonin receptor 0.2244 0.5383 1
Echinococcus multilocularis sodium and chloride dependent glycine 0.0113 0.02 0.0219
Brugia malayi nuclear hormone receptor 0.007 0.0097 0.0176
Brugia malayi Steroid receptor seven-up type 2 0.007 0.0097 0.0176
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0057 0.0064 0.0202
Loa Loa (eye worm) hypothetical protein 0.0059 0.007 0.0143
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0085 0.0134 0.0244
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0181 0.0365 0.0399
Loa Loa (eye worm) hypothetical protein 0.0057 0.0064 0.0131
Echinococcus multilocularis short transient receptor potential channel 6 0.006 0.0072 0.0078
Brugia malayi cytoplasmic intermediate filament protein 0.0044 0.0033 0.0056
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0068 0.0092 0.0238
Plasmodium falciparum thioredoxin reductase 0.1577 0.376 1
Treponema pallidum thioredoxin reductase (trxB) 0.0316 0.0693 0.2415
Brugia malayi hypothetical protein 0.0057 0.0064 0.0115
Brugia malayi Latrophilin receptor protein 2 0.0111 0.0195 0.0358
Schistosoma mansoni voltage-gated potassium channel 0.0059 0.007 0.0079
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0025 0.0078
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0151 0.0293 0.0338
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.006 0.0071 0.0069
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.006 0.0071 0.0078
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.007 0.0097 0.0106
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0075 0.0108 0.0118
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0158 0.031 0.0824
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.014 0.0266 0.0701
Echinococcus granulosus sex peptide receptor 0.0308 0.0676 0.0739
Trypanosoma cruzi cdc2-related kinase 3 0.0054 0.0057 0.0055
Loa Loa (eye worm) hypothetical protein 0.0598 0.1379 0.2808
Loa Loa (eye worm) hypothetical protein 0.0037 0.0017 0.0034
Schistosoma mansoni hypothetical protein 0.0035 0.0013 0.0012
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0048 0.0044 0.0076
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.1189 0.2816 0.749
Leishmania major ferric reductase, putative 0.0073 0.0104 0.0102
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0043 0.0031 0.0029
Brugia malayi Carboxylesterase family protein 0.0057 0.0064 0.0115
Mycobacterium ulcerans carbon monoxide dehydrogenase 0.0112 0.0199 0.07
Toxoplasma gondii DNA topoisomerase 2, putative 0.0375 0.0838 0.2229
Loa Loa (eye worm) hypothetical protein 0.0349 0.0775 0.1579
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0085 0.0134 0.0146
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.0189 0.0595
Onchocerca volvulus Alhambra homolog 0.0058 0.0067 0.0204
Loa Loa (eye worm) latrophilin receptor protein 2 0.0111 0.0195 0.0397
Echinococcus multilocularis 6 phosphofructokinase 0.0108 0.0189 0.0207
Echinococcus granulosus neural cadherin 0.0035 0.0013 0.0014
Echinococcus granulosus RUN 0.0157 0.0307 0.0336
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0108 0.0189 0.0495
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0036 0.0013 0.0159
Onchocerca volvulus Adenylate cyclase type 3 homolog 0.0211 0.044 0.147
Loa Loa (eye worm) hypothetical protein 0.0792 0.1852 0.377
Echinococcus multilocularis musashi 0.0082 0.0125 0.0137
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0068 0.0092 0.0319
Trypanosoma cruzi cdc2-related kinase 3 0.0054 0.0057 0.0055
Schistosoma mansoni glutamate receptor NMDA 0.0321 0.0706 0.0818
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0308 0.0676 0.0783
Schistosoma mansoni hypothetical protein 0.0035 0.0013 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0107 0.0187 0.0586
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0308 0.0676 0.1251
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0113 0.02 0.0367
Leishmania major protein kinase, putative 0.0043 0.0031 0.0029
Loa Loa (eye worm) hypothetical protein 0.0308 0.0676 0.1376
Loa Loa (eye worm) hypothetical protein 0.027 0.0583 0.1188
Mycobacterium tuberculosis Probable dehydrogenase 0.063 0.1458 0.3874
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0308 0.0676 0.0783
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0238 0.0505 0.0503
Schistosoma mansoni voltage-gated potassium channel 0.0059 0.007 0.0079
Echinococcus granulosus transient receptor potential cation channel 0.0059 0.007 0.0077
Brugia malayi jmjC domain containing protein 0.0034 0.001 0.0013
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0109 0.0191 0.0189
Echinococcus granulosus transient receptor potential cation channel 0.006 0.0072 0.0078
Brugia malayi PAS domain containing protein 0.0156 0.0306 0.0563
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0059 0.007 0.0077
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0308 0.0676 0.0783
Schistosoma mansoni voltage-gated potassium channel 0.0059 0.007 0.0079
Plasmodium falciparum phd finger protein, putative 0.0058 0.0067 0.0173
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0054 0.0057 0.0153
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0033 0.0007 0.0006
Brugia malayi chromobox protein homolog 3 0.009 0.0146 0.0267
Schistosoma mansoni aldehyde dehydrogenase 0.0195 0.04 0.0463
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0075 0.0108 0.0338
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.4144 1 1
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0158 0.031 0.0339
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0129 0.0241 0.0239
Loa Loa (eye worm) hypothetical protein 0.0113 0.02 0.0408
Schistosoma mansoni transient receptor potential channel 4 0.0059 0.007 0.0079
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0308 0.0676 0.0739
Echinococcus multilocularis Polycystic kidney disease protein 0.0157 0.0307 0.0336
Brugia malayi Adenylyl cyclase protein 0.0076 0.0112 0.0203
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0068 0.0092 0.0319
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0316 0.0693 0.1284
Trypanosoma brucei C-8 sterol isomerase, putative 0.155 0.3694 0.3692
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0316 0.0693 0.2179
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.1189 0.2816 0.7489
Echinococcus multilocularis cyclin dependent kinase 1 0.0054 0.0057 0.0063
Loa Loa (eye worm) hypothetical protein 0.0308 0.0676 0.1376
Schistosoma mansoni glutamate synthase 0.0316 0.0693 0.0804
Echinococcus multilocularis tumor protein p63 0.0732 0.1707 0.1865
Brugia malayi Augmenter of liver regeneration 0.0109 0.0191 0.035
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0044 0.0034 0.0038
Echinococcus granulosus tyrosine protein kinase Src64B 0.0038 0.0018 0.0019
Loa Loa (eye worm) hypothetical protein 0.0081 0.0124 0.0252
Brugia malayi Cytochrome P450 family protein 0.0087 0.0138 0.0252
Plasmodium vivax protein kinase Crk2 0.0054 0.0057 0.015
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0238 0.0505 0.6023
Entamoeba histolytica cell division protein kinase 2, putative 0.0054 0.0057 0.0684
Loa Loa (eye worm) hypothetical protein 0.008 0.0122 0.0248
Schistosoma mansoni inositol monophosphatase 0.0238 0.0505 0.0585
Schistosoma mansoni sulfide quinone reductase 0.0316 0.0693 0.0804
Schistosoma mansoni growth hormone secretagogue receptor 0.0308 0.0676 0.0783
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0048 0.0042 0.0046
Echinococcus granulosus delta-like protein 1 0.0035 0.0013 0.0014
Trypanosoma brucei NADH dehydrogenase 0.0316 0.0693 0.0691
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.1189 0.2816 1
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0114 0.0203 0.0201
Brugia malayi putative neuropeptide receptor 0.0308 0.0676 0.1251
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0038 0.0018 0.0019
Brugia malayi hypothetical protein 0.0519 0.1187 0.2202
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0316 0.0693 0.1908
Loa Loa (eye worm) hypothetical protein 0.0982 0.2315 0.4712
Onchocerca volvulus 0.0113 0.02 0.0656
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0308 0.0676 0.0783
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.0189 0.2258
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0059 0.0071 0.019
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0043 0.0031 0.0029
Loa Loa (eye worm) hypothetical protein 0.0316 0.0693 0.1412
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0059 0.007 0.0077
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0013 0.0032
Trichomonas vaginalis PIKK family atypical protein kinase 0.0086 0.0135 0.0426
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0075 0.0108 0.0123
Schistosoma mansoni tyrosine kinase 0.0147 0.0283 0.0327
Loa Loa (eye worm) cytochrome P450 family protein 0.0087 0.0138 0.0281
Echinococcus multilocularis orexin receptor type 2 0.0308 0.0676 0.0739
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0308 0.0676 0.0739
Brugia malayi follicle stimulating hormone receptor 0.0582 0.1341 0.2487
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.3059 0.7362 0.7362
Echinococcus granulosus protein jagged 1 0.0035 0.0013 0.0014
Trypanosoma brucei protein kinase, putative 0.0153 0.0298 0.0296
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.007 0.0097 0.0106
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0624 0.1443 0.1578
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0238 0.0505 0.1342
Onchocerca volvulus Heterochromatin protein 1 homolog 0.009 0.0146 0.0472
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0075 0.0109 0.0197
Brugia malayi hypothetical protein 0.0308 0.0676 0.1251
Loa Loa (eye worm) hypothetical protein 0.011 0.0193 0.0394
Loa Loa (eye worm) hypothetical protein 0.0308 0.0676 0.1376
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0316 0.0693 0.1284
Brugia malayi Cytochrome P450 family protein 0.0068 0.0092 0.0166
Loa Loa (eye worm) hypothetical protein 0.0059 0.007 0.0143
Echinococcus granulosus glutamate receptor subunit protein glur 0.0068 0.0091 0.01
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0113 0.02 0.0219
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0308 0.0676 0.0739
Schistosoma mansoni tyrosine kinase 0.0079 0.0119 0.0136
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0316 0.0693 0.0691
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0108 0.0189 0.0187
Loa Loa (eye worm) blistered cuticle protein 3 0.0266 0.0573 0.1167
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0054 0.0057 0.0055
Schistosoma mansoni neuropeptide receptor 0.0308 0.0676 0.0783
Schistosoma mansoni hypothetical protein 0.0058 0.0067 0.0076
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.0189 0.0595
Schistosoma mansoni hypothetical protein 0.0316 0.0693 0.0804
Loa Loa (eye worm) hypothetical protein 0.0075 0.0109 0.0221
Onchocerca volvulus 0.0308 0.0676 0.2272
Echinococcus granulosus tumor protein p63 0.0732 0.1707 0.1865
Brugia malayi hypothetical protein 0.0308 0.0676 0.1251
Schistosoma mansoni glutamate receptor kainate 0.0159 0.0312 0.036
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0039 0.0021 0.0023
Trichomonas vaginalis glucosylceramidase, putative 0.0879 0.2063 0.6482
Echinococcus multilocularis rhodopsin orphan GPCR 0.0308 0.0676 0.0739
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.3059 0.7362 0.7362
Onchocerca volvulus 0.0057 0.0064 0.0195
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0169 0.0336 0.062
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0049 0.0045 0.0141
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0181 0.0366 0.04
Toxoplasma gondii cytochrome p450 superfamily protein 0.0068 0.0092 0.0245
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0059 0.007 0.0126
Brugia malayi ion channel NompC 0.0059 0.007 0.0126
Trichomonas vaginalis apoptosis inducing factor, putative 0.0316 0.0693 0.2179
Schistosoma mansoni microtubule-associated protein tau 0.3569 0.8602 1
Schistosoma mansoni voltage-gated ion channel 0.0059 0.007 0.0079
Schistosoma mansoni voltage-gated potassium channel 0.007 0.0096 0.011
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0037 0.0017 0.0054
Loa Loa (eye worm) hypothetical protein 0.2051 0.4912 1
Schistosoma mansoni netrin receptor unc5 0.0048 0.0042 0.0047
Onchocerca volvulus Bile acid receptor homolog 0.007 0.0097 0.0307
Toxoplasma gondii PHD-finger domain-containing protein 0.0058 0.0067 0.0178
Brugia malayi Blistered cuticle protein 3 0.0266 0.0573 0.106
Loa Loa (eye worm) hypothetical protein 0.0523 0.1199 0.2441
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0031 0.0003 0.0004
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.007 0.0097 0.0106
Schistosoma mansoni polycystin 1-related 0.0157 0.0307 0.0355
Loa Loa (eye worm) hypothetical protein 0.004 0.0022 0.0046
Loa Loa (eye worm) phosphofructokinase 0.0108 0.0189 0.0385
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0075 0.0108 0.0123
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.4144 1 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.0621 0.1952
Trichomonas vaginalis CMGC family protein kinase 0.0153 0.0298 0.0937
Loa Loa (eye worm) hypothetical protein 0.0818 0.1914 0.3897
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0059 0.007 0.0186
Echinococcus multilocularis g protein coupled receptor 0.0308 0.0676 0.0739
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0815 0.1907 0.2084
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0113 0.02 0.0533
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0308 0.0676 0.0739
Echinococcus granulosus jun protein 0.0436 0.0986 0.1078
Loa Loa (eye worm) hypothetical protein 0.0308 0.0676 0.1376
Echinococcus multilocularis phd:f box containing protein 0.0034 0.001 0.001
Schistosoma mansoni sodium/chloride dependent transporter 0.0664 0.1541 0.1789
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0316 0.0693 0.0691
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0172 0.0345 0.1147
Schistosoma mansoni cpg binding protein 0.0061 0.0073 0.0083
Schistosoma mansoni hypothetical protein 0.0059 0.007 0.0079
Entamoeba histolytica disulphide oxidoreductase, putative 0.0316 0.0693 0.8273
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0113 0.02 0.0219
Echinococcus multilocularis serotonin receptor 0.0818 0.1914 0.2092
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0034 0.0009 0.001
Echinococcus granulosus tyrosine kinase 0.0034 0.0009 0.001
Loa Loa (eye worm) hypothetical protein 0.0664 0.1541 0.3136
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0308 0.0676 0.0783
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0013 0.0042
Loa Loa (eye worm) cytochrome P450 0.0068 0.0092 0.0187
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0075 0.0108 0.0118
Loa Loa (eye worm) hypothetical protein 0.006 0.0072 0.0146
Brugia malayi Carboxylesterase family protein 0.0336 0.0744 0.1379
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0057 0.018
Schistosoma mansoni nuclear hormone receptor 0.0033 0.0007 0.0006
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.003 0 0.0001
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.0152 0.0174
Loa Loa (eye worm) hypothetical protein 0.0057 0.0064 0.0131
Loa Loa (eye worm) hypothetical protein 0.0308 0.0676 0.1376
Giardia lamblia Kinase, CMGC CDK 0.0054 0.0057 0.0201
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0075 0.0108 0.0118
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0308 0.0676 0.0739
Echinococcus multilocularis para nitrobenzyl esterase 0.0057 0.0064 0.007
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0036 0.0013 0.003
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0316 0.0693 0.0758
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0054 0.0057 0.0117
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0238 0.0505 0.0503
Brugia malayi Nuclear hormone receptor family member nhr-14 0.007 0.0097 0.0176
Loa Loa (eye worm) helicase 0.0036 0.0013 0.0027
Echinococcus granulosus rhodopsin orphan GPCR 0.0308 0.0676 0.0739
Onchocerca volvulus Netrin receptor homolog 0.0055 0.006 0.0179
Loa Loa (eye worm) hypothetical protein 0.009 0.0146 0.0297
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.3494 0.842 0.8419
Echinococcus multilocularis transfer RNA-Lys 0.0115 0.0207 0.0226
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.063 0.1458 0.3874
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0059 0.007 0.0077
Echinococcus granulosus g protein coupled receptor 0.0308 0.0676 0.0739
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0111 0.0195 0.0213
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0059 0.007 0.0068
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.0109 0.0191 0.0208
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0037 0.0017 0.0018
Echinococcus granulosus jumonji domain containing 1A 0.0034 0.001 0.001
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0059 0.007 0.0079
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0308 0.0676 0.0783
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0144 0.0276 0.0319
Echinococcus multilocularis BC026374 protein (S09 family) 0.0057 0.0064 0.007
Loa Loa (eye worm) hypothetical protein 0.011 0.0193 0.0394
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0068 0.0092 0.0238
Schistosoma mansoni cpg binding protein 0.0061 0.0073 0.0083
Echinococcus multilocularis survival motor neuron protein 1 0.0982 0.2315 0.253
Echinococcus granulosus peregrin 0.0058 0.0067 0.0073
Schistosoma mansoni voltage-gated potassium channel 0.0059 0.007 0.0079
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0068 0.0092 0.0319
Onchocerca volvulus 0.0041 0.0025 0.006
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.1503 0.3581 1
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0286 0.0621 0.7414
Echinococcus multilocularis chromobox protein 2 0.0036 0.0013 0.0015
Brugia malayi intermediate filament protein 0.0082 0.0125 0.0228
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0057 0.0064 0.0165
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0087 0.0138 0.0484
Schistosoma mansoni coup transcription factor 0.007 0.0097 0.0111
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0059 0.007 0.0079
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0153 0.0298 0.0296
Echinococcus granulosus orexin receptor type 2 0.0308 0.0676 0.0739
Schistosoma mansoni notch 0.0035 0.0013 0.0012
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.007 0.0097 0.0106
Chlamydia trachomatis DNA gyrase subunit B 0.014 0.0267 0.0893
Echinococcus granulosus insulin receptor 0.0048 0.0042 0.0046
Brugia malayi Cyclic-nucleotide gated cation channel 0.0075 0.0108 0.0195
Brugia malayi Cytochrome P450 family protein 0.0087 0.0138 0.0252
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0144 0.0276 0.0302
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0113 0.02 0.023
Brugia malayi hypothetical protein 0.0266 0.0573 0.106
Echinococcus multilocularis transient receptor potential gamma protein 0.0059 0.007 0.0077
Echinococcus granulosus neurogenic locus notch protein 4 0.0035 0.0013 0.0014
Brugia malayi Immunoglobulin I-set domain containing protein 0.0048 0.0042 0.0074
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0035 0.0013 0.0019
Schistosoma mansoni glutaminase 0.0278 0.0602 0.0698
Trichomonas vaginalis PIKK family atypical protein kinase 0.0123 0.0225 0.0707
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0081 0.0124 0.0142
Loa Loa (eye worm) hypothetical protein 0.0033 0.0007 0.0014
Loa Loa (eye worm) hypothetical protein 0.0308 0.0676 0.1376
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0105 0.0182 0.0209
Echinococcus multilocularis neuropeptide FF receptor 2 0.0308 0.0676 0.0739
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0036 0.0013 0.002
Echinococcus multilocularis potassium voltage gated channel protein 0.0059 0.007 0.0077
Brugia malayi Animal haem peroxidase family protein 0.011 0.0193 0.0355
Trichomonas vaginalis PIKK family atypical protein kinase 0.0078 0.0115 0.0361
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0316 0.0693 0.2179
Echinococcus multilocularis transient receptor potential cation channel 0.006 0.0072 0.0078
Echinococcus granulosus acetylcholinesterase 0.0336 0.0744 0.0813
Schistosoma mansoni acetylcholinesterase 0.0057 0.0064 0.0073
Schistosoma mansoni septate junction protein 0.0035 0.0013 0.0012
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.1339 0.3183 0.6479
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0113 0.02 0.0367
Brugia malayi hypothetical protein 0.0157 0.0307 0.0566
Leishmania major cytochrome p450-like protein 0.0068 0.0092 0.009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0078 0.0115 0.0362
Loa Loa (eye worm) hypothetical protein 0.0308 0.0676 0.1376
Brugia malayi Cadherin domain containing protein 0.0035 0.0013 0.0019
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.008 0.0121 0.0421
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0093 0.0152 0.0166
Loa Loa (eye worm) hypothetical protein 0.0033 0.0007 0.0014
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.0621 0.1952
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0308 0.0676 0.1251
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.0189 0.0595
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0025 0.0078
Echinococcus multilocularis sodium leak channel non selective protein 0.0059 0.007 0.0077
Loa Loa (eye worm) hypothetical protein 0.0239 0.0507 0.1032
Trichomonas vaginalis PIKK family atypical protein kinase 0.0107 0.0187 0.0586
Echinococcus granulosus transient receptor potential cation channel 0.0059 0.007 0.0077
Trypanosoma cruzi cytochrome P450, putative 0.0087 0.0138 0.0136
Brugia malayi Inositol-1 0.0238 0.0505 0.0933
Loa Loa (eye worm) hypothetical protein 0.0044 0.0033 0.0067
Echinococcus multilocularis conserved hypothetical protein 0.0059 0.007 0.0077
Trichomonas vaginalis PIKK family atypical protein kinase 0.0115 0.0205 0.0643
Trichomonas vaginalis PIKK family atypical protein kinase 0.0078 0.0115 0.0362
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0032 0.0005 0.001
Brugia malayi Melatonin receptor type 1A 0.0308 0.0676 0.1251
Echinococcus multilocularis shaker cognate 0.0059 0.007 0.0077
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0316 0.0693 0.1844
Schistosoma mansoni tyrosine kinase 0.0078 0.0115 0.0131
Echinococcus multilocularis rhodopsin orphan GPCR 0.0308 0.0676 0.0739
Onchocerca volvulus Dual oxidase homolog 0.0266 0.0573 0.1923
Brugia malayi Heterochromatin protein 1 0.0151 0.0293 0.054
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0049 0.0045 0.0141
Schistosoma mansoni nuclear receptor nhr-48 0.0033 0.0007 0.0006
Echinococcus multilocularis neuropeptide receptor 0.0308 0.0676 0.0739
Echinococcus multilocularis voltage dependent calcium channel 0.0151 0.0293 0.032
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0068 0.0092 0.009
Loa Loa (eye worm) hypothetical protein 0.0036 0.0013 0.0027
Echinococcus multilocularis voltage gated potassium channel 0.0085 0.0134 0.0146
Loa Loa (eye worm) hypothetical protein 0.0033 0.0007 0.0014
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0075 0.0108 0.0118
Loa Loa (eye worm) hypothetical protein 0.0033 0.0007 0.0014
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0436 0.0986 0.1078
Loa Loa (eye worm) voltage-gated potassium channel 0.0059 0.007 0.0143
Trypanosoma cruzi ferric reductase transmembrane protein, putative 0.0073 0.0104 0.0102
Echinococcus multilocularis tyrosine protein kinase Srms 0.0034 0.0009 0.001
Brugia malayi Animal haem peroxidase family protein 0.011 0.0193 0.0355
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0082 0.0125 0.0255
Loa Loa (eye worm) hypothetical protein 0.0308 0.0676 0.1376
Echinococcus granulosus 7TM GPCR rhodopsin 0.0308 0.0676 0.0739
Schistosoma mansoni biogenic amine receptor 0.0308 0.0676 0.0783
Toxoplasma gondii thioredoxin reductase 0.1577 0.376 1
Trichomonas vaginalis xanthine dehydrogenase, putative 0.017 0.0338 0.1063
Echinococcus multilocularis epidermal growth factor receptor 0.0079 0.0119 0.013
Plasmodium vivax ferrodoxin reductase, putative 0.0316 0.0693 0.1841
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0048 0.0044 0.0042
Onchocerca volvulus Neurogenic locus notch homolog 0.0036 0.0014 0.0024
Trypanosoma cruzi C-8 sterol isomerase, putative 0.155 0.3694 0.3692
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0093 0.0152 0.0166
Echinococcus multilocularis insulin receptor 0.0048 0.0042 0.0046
Echinococcus granulosus neuroligin 0.0057 0.0064 0.007
Echinococcus granulosus transient receptor potential cation channel 0.0059 0.007 0.0077
Plasmodium falciparum protein kinase 5 0.0054 0.0057 0.0147
Trichomonas vaginalis glucosylceramidase, putative 0.1339 0.3183 1
Echinococcus granulosus TRP transient receptor potential channel 0.0059 0.007 0.0077
Loa Loa (eye worm) hypothetical protein 0.0033 0.0007 0.0014
Echinococcus multilocularis 0.0068 0.0092 0.01
Loa Loa (eye worm) hypothetical protein 0.0035 0.0013 0.0025
Echinococcus granulosus neuropeptide FF receptor 2 0.0308 0.0676 0.0739
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0059 0.007 0.0077
Onchocerca volvulus 0.0308 0.0676 0.2272
Loa Loa (eye worm) calcium channel 0.0151 0.0293 0.0596
Schistosoma mansoni 60S ribosomal protein L21 0.007 0.0096 0.011
Loa Loa (eye worm) animal heme peroxidase 0.011 0.0193 0.0394
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0038 0.0018 0.0019
Echinococcus multilocularis serotonin transporter 0.0664 0.1541 0.1684
Schistosoma mansoni cpg binding protein 0.0057 0.0066 0.0074
Echinococcus multilocularis mitogen activated protein kinase 0.0153 0.0298 0.0326
Leishmania major hypothetical protein, conserved 0.0034 0.001 0.0008
Schistosoma mansoni hypothetical protein 0.0035 0.0013 0.0012
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0316 0.0693 0.2456
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.1577 0.376 1
Treponema pallidum fructose-bisphosphate aldolase 0.0286 0.0621 0.2158
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0181 0.0366 0.04
Echinococcus multilocularis biogenic amine (5HT) receptor 0.1045 0.2466 0.2696
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0068 0.0092 0.0319
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0068 0.0092 0.0238
Echinococcus granulosus retinoic acid receptor rxr beta a 0.007 0.0097 0.0106
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0316 0.0693 0.2456
Schistosoma mansoni neuropeptide receptor 0.0308 0.0676 0.0783
Echinococcus multilocularis jumonji domain containing 1A 0.0034 0.001 0.001
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0158 0.031 0.0358
Loa Loa (eye worm) MH2 domain-containing protein 0.0238 0.0505 0.1029
Schistosoma mansoni lamin 0.0082 0.0125 0.0143
Schistosoma mansoni transient receptor potential channel 0.006 0.0072 0.0081
Loa Loa (eye worm) hypothetical protein 0.0059 0.007 0.0143
Loa Loa (eye worm) hypothetical protein 0.0058 0.0067 0.0137
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0316 0.0693 0.0691
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.007 0.0097 0.0176
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0075 0.0108 0.0219
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0093 0.0152 0.0308
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0144 0.0276 0.3297
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0068 0.0092 0.0319
Loa Loa (eye worm) CYP4Cod1 0.0087 0.0138 0.0281
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.006 0.0071 0.0069
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0316 0.0693 0.1908
Echinococcus multilocularis lamin 0.0082 0.0125 0.0137
Echinococcus granulosus lamin dm0 0.0082 0.0125 0.0137
Leishmania major hypothetical protein, conserved 0.0316 0.0693 0.0691
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0308 0.0676 0.0783
Schistosoma mansoni hypothetical protein 0.0816 0.191 0.2219
Echinococcus granulosus tyrosine protein kinase Blk 0.0034 0.0009 0.001
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0035 0.0013 0.0012
Brugia malayi EGF-like domain containing protein 0.0035 0.0013 0.0019
Schistosoma mansoni amine GPCR 0.0308 0.0676 0.0783
Trichomonas vaginalis conserved hypothetical protein 0.009 0.0146 0.0459
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0033 0.0007 0.0008
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0316 0.0693 0.2179
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0316 0.0693 0.2179
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0059 0.007 0.0077
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0059 0.007 0.0079
Loa Loa (eye worm) hypothetical protein 0.0664 0.1541 0.3136
Loa Loa (eye worm) hypothetical protein 0.0113 0.02 0.0408
Loa Loa (eye worm) glutamate receptor 1 0.0159 0.0312 0.0635
Schistosoma mansoni hypothetical protein 0.0157 0.0307 0.0355
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0172 0.0345 0.0377
Schistosoma mansoni neuropeptide f receptor 76f 0.0308 0.0676 0.0783
Trichomonas vaginalis protein kinase inhibitor, putative 0.0062 0.0076 0.024
Echinococcus granulosus rhodopsin orphan GPCR 0.0308 0.0676 0.0739
Schistosoma mansoni phosphatidylserine receptor 0.0034 0.001 0.0009
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0033 0.0007 0.0008
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0316 0.0693 0.1839
Loa Loa (eye worm) hypothetical protein 0.0193 0.0395 0.0804
Trypanosoma brucei cdc2-related kinase 1 0.0054 0.0057 0.0055
Brugia malayi EGF-like domain containing protein 0.0035 0.0013 0.0019
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0181 0.0366 0.04
Echinococcus granulosus potassium large conductance calcium activated 0.0059 0.007 0.0077
Brugia malayi glutamate synthase 0.0316 0.0693 0.1284
Toxoplasma gondii isocitrate dehydrogenase 0.0031 0.0003 0.0007
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0037 0.0017 0.0017
Brugia malayi Nuclear hormone receptor family member nhr-49 0.007 0.0097 0.0176
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0031 0.0003 0.0003
Echinococcus multilocularis chromobox protein 1 0.0151 0.0293 0.032
Echinococcus granulosus adenylate cyclase 9 0.0076 0.0112 0.0122
Onchocerca volvulus 0.0308 0.0676 0.2272
Loa Loa (eye worm) hypothetical protein 0.0308 0.0676 0.1376
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0059 0.007 0.0186
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.1189 0.2816 0.523
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0044 0.0033 0.0103
Trypanosoma cruzi cdc2-related kinase 1 0.0054 0.0057 0.0055
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.1189 0.2816 0.2815
Loa Loa (eye worm) phosphatidylinositol 3 0.0144 0.0276 0.0563
Echinococcus multilocularis lysine specific demethylase 6a 0.0034 0.001 0.001
Echinococcus granulosus neurogenic locus protein delta 0.0035 0.0013 0.0014
Schistosoma mansoni jun-related protein 0.0354 0.0788 0.0913
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.014 0.0266 0.0709
Loa Loa (eye worm) hypothetical protein 0.0033 0.0007 0.0014
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0058 0.0067 0.0076
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0075 0.0108 0.0118
Loa Loa (eye worm) hypothetical protein 0.0075 0.011 0.0223
Schistosoma mansoni hypothetical protein 0.0111 0.0195 0.0224
Echinococcus granulosus two pore calcium channel protein 2 0.0059 0.007 0.0077
Brugia malayi steroid hormone receptor 0.007 0.0097 0.0176
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0068 0.0092 0.0238
Brugia malayi ecdysone receptor 0.0033 0.0007 0.0008
Echinococcus granulosus microtubule associated protein 2 0.3569 0.8602 0.9403
Echinococcus granulosus ATP binding cassette sub family G 0.0031 0.0002 0.0002
Onchocerca volvulus 0.0519 0.1187 0.4009
Trichomonas vaginalis glucosylceramidase, putative 0.1339 0.3183 1
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0181 0.0365 0.0674
Mycobacterium leprae Conserved hypothetical protein 0.0068 0.0092 0.0222
Schistosoma mansoni hypothetical protein 0.0035 0.0013 0.0012
Trichomonas vaginalis glutamate synthase, putative 0.0316 0.0693 0.2179
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0059 0.007 0.0077
Loa Loa (eye worm) melatonin receptor type 1A 0.0308 0.0676 0.1376
Mycobacterium ulcerans aldehyde dehydrogenase 0.0195 0.04 0.1415
Schistosoma mansoni voltage-gated potassium channel 0.0179 0.0362 0.0419
Loa Loa (eye worm) hypothetical protein 0.0308 0.0676 0.1376
Echinococcus granulosus geminin 0.0907 0.2131 0.233
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0258 0.0553 0.1855
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.005 0.0048 0.0165
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.0152 0.0174
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0316 0.0693 0.0691
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0111 0.0195 0.0213
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0316 0.0693 0.0758
Loa Loa (eye worm) hypothetical protein 0.0035 0.0013 0.0025
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0075 0.0108 0.0123
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0068 0.0092 0.0319
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0041 0.0025 0.0027
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0113 0.02 0.023
Brugia malayi MAP kinase sur-1 0.0153 0.0298 0.055
Mycobacterium tuberculosis DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0078 0.0115 0.03
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0308 0.0676 0.0739
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0105 0.0182 0.0209
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0113 0.02 0.0653
Leishmania major hypothetical protein, conserved 0.0316 0.0693 0.0691
Echinococcus granulosus G protein coupled receptor 139 0.0308 0.0676 0.0739
Plasmodium falciparum JmjC domain-containing protein, putative 0.0034 0.001 0.002
Onchocerca volvulus 0.006 0.0073 0.0225
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.0189 0.2258
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0144 0.0276 0.0274
Brugia malayi jmjC domain containing protein 0.0034 0.001 0.0013
Onchocerca volvulus 0.0308 0.0676 0.2272
Onchocerca volvulus 0.0081 0.0124 0.0397
Toxoplasma gondii EGF family domain-containing protein 0.0035 0.0013 0.0033
Schistosoma mansoni gliotactin 0.0057 0.0064 0.0073
Schistosoma mansoni ryanodine receptor related 0.0059 0.007 0.0079
Echinococcus multilocularis Ankyrin 0.0044 0.0034 0.0037
Schistosoma mansoni peroxidasin 0.011 0.0193 0.0222
Brugia malayi GCC2 and GCC3 family protein 0.0035 0.0013 0.0019
Schistosoma mansoni glutamate receptor kainate 0.0159 0.0312 0.036
Echinococcus granulosus lamin 0.0082 0.0125 0.0137
Loa Loa (eye worm) hypothetical protein 0.0077 0.0112 0.0228
Loa Loa (eye worm) hypothetical protein 0.0173 0.0346 0.0705
Brugia malayi cell division control protein 2 homolog 0.0054 0.0057 0.0102
Brugia malayi Peroxidasin 0.0114 0.0203 0.0372
Echinococcus granulosus Ankyrin 0.0044 0.0034 0.0037
Echinococcus granulosus tachykinin peptides receptor 99D 0.0308 0.0676 0.0739
Brugia malayi Doublecortin family protein 0.0157 0.0307 0.0566
Onchocerca volvulus Adenylate cyclase type 2 homolog 0.0076 0.0112 0.0355
Echinococcus multilocularis glutamate receptor 2 0.0181 0.0366 0.04
Loa Loa (eye worm) hypothetical protein 0.0308 0.0676 0.1376
Brugia malayi Glutamate receptor 2 precursor 0.0159 0.0312 0.0575
Echinococcus multilocularis GPCR, family 2 0.0111 0.0195 0.0213
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0057 0.0064 0.0073
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0316 0.0693 0.1844
Brugia malayi EGF-like domain containing protein 0.0035 0.0013 0.0019
Onchocerca volvulus 0.0107 0.0187 0.0611
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0033 0.0007 0.0008
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0113 0.02 0.023
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0068 0.0092 0.0238
Schistosoma mansoni hypothetical protein 0.0308 0.0676 0.0783
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0161 0.0318 0.0648
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0033 0.0007 0.0008
Loa Loa (eye worm) hypothetical protein 0.0035 0.0013 0.0025
Schistosoma mansoni nuclear hormone receptor 0.0033 0.0007 0.0006
Plasmodium vivax hypothetical protein, conserved 0.0058 0.0067 0.0175
Echinococcus multilocularis fmrfamide receptor 0.0308 0.0676 0.0739
Brugia malayi exodeoxyribonuclease III family protein 0.006 0.0071 0.0128
Schistosoma mansoni disulfide oxidoreductase 0.0316 0.0693 0.0804
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0172 0.0345 0.0701
Brugia malayi DnaJ domain containing protein 0.0062 0.0076 0.0137
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0038 0.0018 0.0019
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0316 0.0693 0.8273
Brugia malayi G protein-coupled receptor F59B2.13 0.0308 0.0676 0.1251
Schistosoma mansoni 6-phosphofructokinase 0.0108 0.0189 0.0218
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0225 0.0472 0.0516
Schistosoma mansoni hypothetical protein 0.0111 0.0195 0.0224
Loa Loa (eye worm) hypothetical protein 0.0035 0.0013 0.0025
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0034 0.001 0.0026
Brugia malayi neuropeptide F receptor 0.0308 0.0676 0.1251
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0075 0.0108 0.0118
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0068 0.0091 0.01
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0044 0.0137
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0034 0.001 0.0009
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0059 0.007 0.0126
Schistosoma mansoni calcium-activated potassium channel 0.0059 0.007 0.0079
Brugia malayi 6-phosphofructokinase 0.0108 0.0189 0.0347
Echinococcus multilocularis jun protein 0.0436 0.0986 0.1078
Onchocerca volvulus 0.011 0.0193 0.0633

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 0.33 uM Inhibition of Cyclin-dependent kinase 1 (CDK1) ChEMBL. 11063606

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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