Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | tar DNA-binding protein | 0.007 | 0.0656 | 0.1216 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0192 | 0.247 | 0.2389 |
Brugia malayi | O-Glycosyl hydrolase family 30 protein | 0.0222 | 0.2923 | 0.5781 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0363 | 0.5018 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0043 | 0.0254 | 0.0407 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0363 | 0.5018 | 0.4965 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0171 | 0.2164 | 0.4211 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0171 | 0.2164 | 0.4253 |
Onchocerca volvulus | 0.0171 | 0.2164 | 0.419 | |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0146 | 0.1786 | 0.3766 |
Loa Loa (eye worm) | hypothetical protein | 0.0363 | 0.5018 | 1 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0171 | 0.2164 | 0.4211 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0192 | 0.247 | 0.4868 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0171 | 0.2164 | 0.208 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0051 | 0.0369 | 0.0638 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0051 | 0.0369 | 0.0266 |
Loa Loa (eye worm) | hypothetical protein | 0.0171 | 0.2164 | 0.4253 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0146 | 0.1786 | 0.3766 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0363 | 0.5018 | 1 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0171 | 0.2164 | 0.208 |
Onchocerca volvulus | Glucosylceramidase homolog | 0.0146 | 0.1786 | 0.3419 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0363 | 0.5018 | 1 |
Brugia malayi | jmjC domain containing protein | 0.0051 | 0.0369 | 0.0638 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0104 | 0.1167 | 0.2105 |
Loa Loa (eye worm) | TAR-binding protein | 0.007 | 0.0656 | 0.1216 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0363 | 0.5018 | 1 |
Echinococcus granulosus | L aminoadipate semialdehyde | 0.0092 | 0.0982 | 0.1812 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0171 | 0.2164 | 0.4253 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.0104 | 0.1167 | 0.2189 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0104 | 0.1167 | 0.2105 |
Giardia lamblia | Kinase, PLK | 0.0104 | 0.1167 | 0.5 |
Brugia malayi | hypothetical protein | 0.0192 | 0.247 | 0.4868 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0192 | 0.247 | 0.4868 |
Loa Loa (eye worm) | DR-78 | 0.0171 | 0.2164 | 0.4253 |
Loa Loa (eye worm) | hypothetical protein | 0.0192 | 0.247 | 0.4868 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0171 | 0.2164 | 0.208 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0192 | 0.247 | 0.4831 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0043 | 0.0254 | 0.0407 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0222 | 0.2923 | 0.6822 |
Brugia malayi | nuclear hormone receptor | 0.0171 | 0.2164 | 0.4253 |
Loa Loa (eye worm) | hypothetical protein | 0.0192 | 0.247 | 0.4868 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0171 | 0.2164 | 0.4253 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0051 | 0.0369 | 0.057 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0222 | 0.2923 | 0.6822 |
Onchocerca volvulus | Serine\/threonine kinase homolog | 0.0104 | 0.1167 | 0.216 |
Trichomonas vaginalis | glutaminase, putative | 0.0302 | 0.4106 | 1 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0171 | 0.2164 | 0.4253 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0363 | 0.5018 | 0.4965 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0171 | 0.2164 | 0.4211 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0363 | 0.5018 | 0.4965 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0363 | 0.5018 | 1 |
Brugia malayi | ecdysone receptor | 0.0171 | 0.2164 | 0.4253 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0363 | 0.5018 | 0.4965 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0363 | 0.5018 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0146 | 0.1786 | 0.3766 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0363 | 0.5018 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0363 | 0.5018 | 1 |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.0104 | 0.1167 | 0.1073 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0192 | 0.247 | 0.4868 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0363 | 0.5018 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0192 | 0.247 | 0.4868 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0363 | 0.5018 | 1 |
Onchocerca volvulus | 0.0262 | 0.3507 | 0.6923 | |
Trichomonas vaginalis | CAMK family protein kinase | 0.0104 | 0.1167 | 0.2105 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0254 | 0.0407 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0363 | 0.5018 | 1 |
Schistosoma mansoni | glutaminase | 0.0302 | 0.4106 | 0.8163 |
Brugia malayi | nuclear receptor NHR-67 | 0.0171 | 0.2164 | 0.4253 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0104 | 0.1167 | 0.2105 |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.0104 | 0.1167 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0033 | 0.0106 | 0.0109 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0104 | 0.1167 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0192 | 0.247 | 0.4868 |
Loa Loa (eye worm) | hypothetical protein | 0.0363 | 0.5018 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0104 | 0.1167 | 0.2105 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0051 | 0.0369 | 0.0266 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0363 | 0.5018 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0363 | 0.5018 | 0.4965 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0171 | 0.2164 | 0.419 |
Onchocerca volvulus | 0.0171 | 0.2164 | 0.419 | |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0222 | 0.2923 | 0.6822 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0363 | 0.5018 | 1 |
Brugia malayi | serine/threonine-protein kinase plk-2 | 0.0104 | 0.1167 | 0.2246 |
Schistosoma mansoni | tar DNA-binding protein | 0.007 | 0.0656 | 0.1216 |
Loa Loa (eye worm) | hypothetical protein | 0.0171 | 0.2164 | 0.4253 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0154 | 0.1903 | 0.408 |
Loa Loa (eye worm) | hypothetical protein | 0.0171 | 0.2164 | 0.4253 |
Brugia malayi | jmjC domain containing protein | 0.0051 | 0.0369 | 0.0638 |
Brugia malayi | hypothetical protein | 0.0171 | 0.2164 | 0.4253 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0363 | 0.5018 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0146 | 0.1786 | 0.3766 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0363 | 0.5018 | 0.4965 |
Brugia malayi | Pre-SET motif family protein | 0.0033 | 0.0106 | 0.0109 |
Schistosoma mansoni | nuclear hormone receptor | 0.0171 | 0.2164 | 0.4253 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0363 | 0.5018 | 1 |
Echinococcus granulosus | FTZ F1 alpha | 0.0363 | 0.5018 | 1 |
Schistosoma mansoni | aminoadipate-semialdehyde dehydrogenase | 0.0092 | 0.0982 | 0.1871 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0171 | 0.2164 | 0.4211 |
Treponema pallidum | 4'-phosphopantetheinyl transferase | 0.0026 | 0 | 0.5 |
Brugia malayi | aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase | 0.0092 | 0.0982 | 0.1871 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0363 | 0.5018 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.007 | 0.0656 | 0.1216 |
Loa Loa (eye worm) | hypothetical protein | 0.0171 | 0.2164 | 0.4253 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0171 | 0.2164 | 0.4253 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0171 | 0.2164 | 0.4253 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0222 | 0.2923 | 0.6822 |
Onchocerca volvulus | 0.0092 | 0.0982 | 0.1782 | |
Loa Loa (eye worm) | hypothetical protein | 0.0171 | 0.2164 | 0.4253 |
Schistosoma mansoni | zinc finger protein | 0.0171 | 0.2164 | 0.4253 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0363 | 0.5018 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0363 | 0.5018 | 1 |
Onchocerca volvulus | 0.0363 | 0.5018 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0363 | 0.5018 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0033 | 0.0106 | 0.0109 |
Schistosoma mansoni | tar DNA-binding protein | 0.007 | 0.0656 | 0.1216 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0363 | 0.5018 | 1 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0192 | 0.247 | 0.4868 |
Loa Loa (eye worm) | hypothetical protein | 0.0171 | 0.2164 | 0.4253 |
Brugia malayi | nuclear receptor RXR | 0.0192 | 0.247 | 0.4868 |
Loa Loa (eye worm) | glutaminase 2 | 0.0302 | 0.4106 | 0.8163 |
Brugia malayi | glutaminase DH11.1 | 0.0302 | 0.4106 | 0.8163 |
Mycobacterium leprae | conserved hypothetical protein | 0.0026 | 0 | 0.5 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0051 | 0.0369 | 0.0638 |
Schistosoma mansoni | nuclear hormone receptor | 0.0363 | 0.5018 | 1 |
Leishmania major | protein kinase, putative,polo-like protein kinase, putative | 0.0104 | 0.1167 | 1 |
Brugia malayi | nuclear hormone receptor | 0.0363 | 0.5018 | 1 |
Brugia malayi | hypothetical protein | 0.0171 | 0.2164 | 0.4253 |
Loa Loa (eye worm) | hypothetical protein | 0.0192 | 0.247 | 0.4868 |
Brugia malayi | conserved hypotetical protein | 0.0171 | 0.2164 | 0.4253 |
Brugia malayi | Pre-SET motif family protein | 0.023 | 0.3034 | 0.6005 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.0104 | 0.1167 | 0.2246 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0363 | 0.5018 | 1 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0363 | 0.5018 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0363 | 0.5018 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0363 | 0.5018 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0106 | 0.0109 |
Echinococcus multilocularis | L aminoadipate semialdehyde | 0.0092 | 0.0982 | 0.0885 |
Brugia malayi | TAR-binding protein | 0.007 | 0.0656 | 0.1216 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0192 | 0.247 | 0.4868 |
Loa Loa (eye worm) | hypothetical protein | 0.0171 | 0.2164 | 0.4253 |
Loa Loa (eye worm) | glutaminase | 0.0302 | 0.4106 | 0.8163 |
Wolbachia endosymbiont of Brugia malayi | 4'-phosphopantetheinyl transferase | 0.0026 | 0 | 0.5 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0104 | 0.1167 | 0.2105 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0171 | 0.2164 | 0.4253 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0171 | 0.2164 | 0.208 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0171 | 0.2164 | 0.4253 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0363 | 0.5018 | 1 |
Brugia malayi | RNA recognition motif domain containing protein | 0.007 | 0.0656 | 0.1216 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0104 | 0.1167 | 0.5 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.023 | 0.3034 | 0.6005 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.007 | 0.0656 | 0.1216 |
Loa Loa (eye worm) | hypothetical protein | 0.0171 | 0.2164 | 0.4253 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0171 | 0.2164 | 0.4253 |
Echinococcus granulosus | tar DNA binding protein | 0.007 | 0.0656 | 0.1153 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0043 | 0.0254 | 0.0407 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0146 | 0.1786 | 0.3766 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0363 | 0.5018 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.007 | 0.0656 | 0.1216 |
Schistosoma mansoni | jumonji domain containing protein | 0.0051 | 0.0369 | 0.0638 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0363 | 0.5018 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.007 | 0.0656 | 0.1216 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0363 | 0.5018 | 1 |
Brugia malayi | nuclear receptor NHR-88 | 0.0171 | 0.2164 | 0.4253 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0154 | 0.1903 | 0.408 |
Loa Loa (eye worm) | hypothetical protein | 0.0171 | 0.2164 | 0.4253 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0363 | 0.5018 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0363 | 0.5018 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0171 | 0.2164 | 0.4253 |
Brugia malayi | RNA binding protein | 0.007 | 0.0656 | 0.1216 |
Chlamydia trachomatis | holo [acyl-carrier protein] synthase | 0.0026 | 0 | 0.5 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0363 | 0.5018 | 1 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0171 | 0.2164 | 0.4211 |
Schistosoma mansoni | nuclear hormone receptor | 0.0171 | 0.2164 | 0.4253 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0363 | 0.5018 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0171 | 0.2164 | 0.208 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0363 | 0.5018 | 1 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0363 | 0.5018 | 1 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0171 | 0.2164 | 0.4253 |
Loa Loa (eye worm) | hypothetical protein | 0.0363 | 0.5018 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0222 | 0.2923 | 0.6822 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0222 | 0.2923 | 0.6822 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0363 | 0.5018 | 1 |
Brugia malayi | nuclear receptor NHR-88 | 0.0363 | 0.5018 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0033 | 0.0106 | 0.0109 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0171 | 0.2164 | 0.419 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0363 | 0.5018 | 0.4965 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0363 | 0.5018 | 1 |
Schistosoma mansoni | nuclear receptor | 0.0171 | 0.2164 | 0.4253 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0363 | 0.5018 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0363 | 0.5018 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0171 | 0.2164 | 0.4253 |
Loa Loa (eye worm) | hypothetical protein | 0.0171 | 0.2164 | 0.4253 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0363 | 0.5018 | 1 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0363 | 0.5018 | 1 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0033 | 0.0106 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0363 | 0.5018 | 1 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0171 | 0.2164 | 0.4211 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0363 | 0.5018 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0171 | 0.2164 | 0.4253 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0363 | 0.5018 | 1 |
Schistosoma mansoni | coup transcription factor | 0.0363 | 0.5018 | 1 |
Plasmodium vivax | SET domain protein, putative | 0.0033 | 0.0106 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0146 | 0.1786 | 0.3766 |
Loa Loa (eye worm) | hypothetical protein | 0.0092 | 0.0982 | 0.1871 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0051 | 0.0369 | 0.057 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0363 | 0.5018 | 1 |
Mycobacterium ulcerans | glutaminase | 0.0302 | 0.4106 | 1 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0171 | 0.2164 | 0.208 |
Schistosoma mansoni | nuclear receptor | 0.0171 | 0.2164 | 0.4253 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0363 | 0.5018 | 1 |
Brugia malayi | tailless protein | 0.0171 | 0.2164 | 0.4253 |
Brugia malayi | hypothetical protein | 0.0192 | 0.247 | 0.4868 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0146 | 0.1786 | 0.3766 |
Brugia malayi | nuclear receptor RXR | 0.0171 | 0.2164 | 0.4253 |
Schistosoma mansoni | kinase | 0.0053 | 0.0404 | 0.0709 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0051 | 0.0369 | 0.0638 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0033 | 0.0106 | 0.0037 |
Brugia malayi | steroid hormone receptor | 0.0363 | 0.5018 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0033 | 0.0106 | 0.0109 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0363 | 0.5018 | 1 |
Echinococcus multilocularis | tar DNA binding protein | 0.007 | 0.0656 | 0.0556 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0171 | 0.2164 | 0.4253 |
Trypanosoma brucei | polo-like protein kinase | 0.0104 | 0.1167 | 1 |
Plasmodium falciparum | holo-[acyl-carrier-protein] synthase, putative | 0.0026 | 0 | 0.5 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0363 | 0.5018 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0363 | 0.5018 | 1 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0363 | 0.5018 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0363 | 0.5018 | 1 |
Trichomonas vaginalis | set domain proteins, putative | 0.0262 | 0.3507 | 0.839 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0104 | 0.1167 | 0.2246 |
Loa Loa (eye worm) | hypothetical protein | 0.0363 | 0.5018 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0171 | 0.2164 | 0.4253 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0363 | 0.5018 | 0.4965 |
Brugia malayi | ecdysteroid receptor | 0.0363 | 0.5018 | 1 |
Mycobacterium tuberculosis | holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie | 0.0026 | 0 | 0.5 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0104 | 0.1167 | 0.2105 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.0222 | 0.2923 | 0.5781 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0363 | 0.5018 | 0.4965 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
CC50 (ADMET) | > 250 uM | Cytotoxicity against HEK293 cells assessed as cell viability after 24 hrs by MTT assay | ChEMBL. | 24313730 |
IC50 (binding) | > 200 uM | Inhibition of Influenza A virus (A/Puerto Rico/8/34(H1N1)) His6-tagged PA (239 to 716) interaction with GST-tagged PB1 (1 to 25) expressed in Escherichia coli BL21 (DE3) by ELISA | ChEMBL. | 24313730 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.