Detailed information for compound 18244

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 412.371 | Formula: C19H25O8P--
  • H donors: 2 H acceptors: 6 LogP: 0.56 Rotable bonds: 10
    Rule of 5 violations (Lipinski): 1
  • SMILES: C/C=C/C=C\C=C\[C@H](C[C@H]([C@](/C=C/[C@@H]1CC=CC(=O)O1)(O)C)OP(=O)([O-])[O-])O
  • InChi: 1S/C19H27O8P/c1-3-4-5-6-7-9-15(20)14-17(27-28(23,24)25)19(2,22)13-12-16-10-8-11-18(21)26-16/h3-9,11-13,15-17,20,22H,10,14H2,1-2H3,(H2,23,24,25)/p-2/b4-3+,6-5-,9-7-,13-12+/t15-,16+,17+,19+/m0/s1
  • InChiKey: MQLGXVOINDPKQT-BDLLLQCCSA-L  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium tuberculosis Conserved protein 0.0038 0.0173 0.0421
Loa Loa (eye worm) hypothetical protein 0.0083 0.0435 0.0462
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0025 0.0091 0.0096
Loa Loa (eye worm) pre-B cell enhancing factor 0.0388 0.2236 0.2379
Treponema pallidum ribonuclease H (rnhA) 0.0021 0.0072 0.0056
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0173 0.0941
Schistosoma mansoni amine GPCR 0.0083 0.0435 0.0462
Brugia malayi Tachykinin-like peptides receptor 99D 0.0083 0.0435 0.0462
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0083 0.0435 0.0435
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0119 0.0625
Brugia malayi latrophilin 2 splice variant baaae 0.0103 0.0554 0.0589
Schistosoma mansoni hypothetical protein 0.0048 0.0227 0.0242
Loa Loa (eye worm) hypothetical protein 0.0048 0.0231 0.0246
Plasmodium vivax hypothetical protein, conserved 0.0028 0.0114 0.0308
Loa Loa (eye worm) hypothetical protein 0.1603 0.9399 1
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0312 0.1783 0.1896
Brugia malayi RE15519p 0.0083 0.0435 0.0462
Brugia malayi sulfakinin receptor protein 0.0083 0.0435 0.0462
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0068 0.0346 0.0346
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0026 0.0097 0.0103
Echinococcus granulosus serotonin receptor 0.0083 0.0435 0.0462
Echinococcus multilocularis bloom syndrome protein 0.0021 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.0083 0.0435 0.0462
Toxoplasma gondii DNA topoisomerase 2, putative 0.0068 0.0349 0.0951
Mycobacterium tuberculosis Probable thymidylate synthase ThyA (ts) (TSASE) 0.0631 0.3666 1
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.0213 0.0226
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0083 0.0435 0.0462
Schistosoma mansoni cellular tumor antigen P53 0.0053 0.0258 0.0274
Mycobacterium tuberculosis Nicotinic acid phosphoribosyltransferase PncB1 0.0072 0.0371 0.0963
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0039 0.0174 0.0185
Schistosoma mansoni DNA topoisomerase II 0.0068 0.0349 0.0371
Echinococcus granulosus tumor protein p63 0.0361 0.2076 0.2209
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0048 0.0227 0.0242
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0213 0.0226
Mycobacterium ulcerans esterase/lipase LipP 0.0038 0.0173 0.0425
Echinococcus granulosus thioredoxin glutathione reductase 0.0097 0.0516 0.0549
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0083 0.0435 0.0462
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0038 0.0173 0.0184
Echinococcus granulosus histone lysine methyltransferase setb 0.0019 0.006 0.0064
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0093 0.0496 0.0527
Brugia malayi jmjC domain containing protein 0.0037 0.0162 0.0172
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0034 0.0143 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0032 0.0034
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0029 0.0119 0.1852
Brugia malayi 6-phosphofructokinase 0.0109 0.0587 0.0624
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0083 0.0435 0.0462
Echinococcus granulosus g protein coupled receptor 0.0083 0.0435 0.0462
Brugia malayi F/Y-rich N-terminus family protein 0.0011 0.0013 0.0014
Plasmodium vivax thioredoxin reductase, putative 0.0097 0.0516 0.1406
Schistosoma mansoni zinc finger protein 0.0022 0.0077 0.0082
Trichomonas vaginalis protein phosphatase PP2A regulatory subunit B, putative 0.0074 0.038 0.2158
Trichomonas vaginalis nicotinate phosphoribosyltransferase, putative 0.0072 0.0371 0.2102
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0119 0.0323
Schistosoma mansoni hypothetical protein 0.0103 0.0554 0.0589
Schistosoma mansoni nicotinate phosphoribosyltransferase 0.0072 0.0371 0.0394
Schistosoma mansoni opsin-like receptor 0.0083 0.0435 0.0462
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0029 0.0119 0.0625
Echinococcus granulosus 7TM GPCR rhodopsin 0.0083 0.0435 0.0462
Toxoplasma gondii PHD-finger domain-containing protein 0.0009 0.0001 0.0001
Schistosoma mansoni 6-phosphofructokinase 0.0109 0.0587 0.0624
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0034 0.0143 1
Echinococcus granulosus ribonuclease H1 0.0021 0.0072 0.0076
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0061 0.0308 0.084
Plasmodium falciparum glutathione reductase 0.0097 0.0516 0.1406
Onchocerca volvulus 0.0083 0.0435 0.0462
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0019 0.0056 0.015
Loa Loa (eye worm) intermediate filament protein 0.008 0.0419 0.0445
Entamoeba histolytica DNA topoisomerase II, putative 0.0068 0.0349 0.5858
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0083 0.0435 0.0462
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0029 0.0119 0.1536
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0272 0.1551 0.1649
Loa Loa (eye worm) jmjC domain-containing protein 0.0059 0.0292 0.0311
Loa Loa (eye worm) hypothetical protein 0.0083 0.0435 0.0462
Echinococcus multilocularis neuropeptide receptor A26 0.0561 0.3255 0.3255
Echinococcus granulosus rhodopsin orphan GPCR 0.0083 0.0435 0.0462
Loa Loa (eye worm) 6-phosphofructokinase 0.0109 0.0587 0.0624
Echinococcus granulosus biogenic amine 5HT receptor 0.0466 0.2693 0.2865
Brugia malayi Dopamine receptor protein 2 0.0083 0.0435 0.0462
Loa Loa (eye worm) hypothetical protein 0.1603 0.9399 1
Brugia malayi Serotonin receptor 0.0083 0.0435 0.0462
Loa Loa (eye worm) hypothetical protein 0.0046 0.0216 0.023
Trypanosoma brucei retrotransposon hot spot protein 4 (RHS4), interrupted 0.0023 0.0082 0.0223
Loa Loa (eye worm) jmjC domain-containing protein 0.0037 0.0162 0.0172
Onchocerca volvulus DNA topoisomerase 2 homolog 0.005 0.0238 0.0253
Mycobacterium tuberculosis Probable hydrolase 0.0038 0.0173 0.0421
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0048 0.0227 0.0242
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0119 0.0651
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0034 0.0143 0.0153
Loa Loa (eye worm) hypothetical protein 0.0083 0.0435 0.0462
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0022 0.0078 0.0063
Schistosoma mansoni nicotinate phosphoribosyltransferase related pre-B cell enhancing factor 0.0388 0.2236 0.2379
Schistosoma mansoni hypothetical protein 0.0028 0.0114 0.0121
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.038 0.1006
Plasmodium vivax bifunctional dihydrofolate reductase-thymidylate synthase, putative 0.0631 0.3666 1
Brugia malayi Bloom's syndrome protein homolog 0.0021 0.0071 0.0075
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0083 0.0435 0.0462
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0019 0.006 0.006
Brugia malayi thymidylate synthase 0.0631 0.3666 0.39
Loa Loa (eye worm) neuropeptide F receptor 0.0083 0.0435 0.0462
Echinococcus multilocularis neuropeptides capa receptor 0.0083 0.0435 0.0435
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0038 0.0173 0.0421
Toxoplasma gondii NADPH-glutathione reductase 0.0034 0.0143 0.039
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0245 0.1392 0.3489
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0221 0.1247 0.3074
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0083 0.0435 0.0435
Toxoplasma gondii hypothetical protein 0.0272 0.1551 0.4229
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0083 0.0435 0.0435
Loa Loa (eye worm) hypothetical protein 0.0083 0.0435 0.0462
Loa Loa (eye worm) hypothetical protein 0.0083 0.0435 0.0462
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0221 0.1247 0.3365
Echinococcus granulosus neuropeptide s receptor 0.0561 0.3255 0.3463
Schistosoma mansoni hypothetical protein 0.0515 0.2982 0.3172
Schistosoma mansoni hypothetical protein 0.0083 0.0435 0.0462
Schistosoma mansoni sodium-dependent amino acid transporter 0.0272 0.1551 0.1649
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0083 0.0435 0.0462
Plasmodium falciparum thioredoxin reductase 0.0097 0.0516 0.1406
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0272 0.1551 0.1649
Plasmodium falciparum DNA gyrase subunit B 0.0022 0.0078 0.0212
Schistosoma mansoni hypothetical protein 0.0205 0.1155 0.1228
Trypanosoma cruzi protein phosphatase 2A regulatory subunit, putative 0.0074 0.038 0.1006
Loa Loa (eye worm) PHD-finger family protein 0.0028 0.0114 0.0121
Echinococcus granulosus lamin 0.008 0.0419 0.0446
Loa Loa (eye worm) hypothetical protein 0.0103 0.0554 0.0589
Loa Loa (eye worm) thioredoxin reductase 0.0097 0.0516 0.0549
Echinococcus granulosus allatostatin A receptor 0.0083 0.0435 0.0462
Trichomonas vaginalis phosphofructokinase, putative 0.0109 0.0587 0.3371
Echinococcus granulosus 7tm_1 domain containing protein 0.0083 0.0435 0.0462
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0011 0.0013 0.0033
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0083 0.0435 0.0435
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0019 0.006 0.0064
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0083 0.0435 0.0435
Plasmodium vivax hypothetical protein, conserved 0.0038 0.0173 0.047
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0083 0.0435 0.0462
Echinococcus multilocularis g protein coupled receptor 0.0083 0.0435 0.0435
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0083 0.0435 0.0462
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0034 0.0143 0.0389
Toxoplasma gondii ABC1 family protein 0.0038 0.0173 0.0471
Leishmania major dihydrofolate reductase-thymidylate synthase 0.0631 0.3666 1
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0017 0.0046 0.0048
Schistosoma mansoni adenoreceptor 0.0083 0.0435 0.0462
Onchocerca volvulus 0.0083 0.0435 0.0462
Echinococcus granulosus zinc finger protein 0.0022 0.0077 0.0082
Brugia malayi AKH receptor 0.0083 0.0435 0.0462
Brugia malayi Smad1 0.0017 0.0046 0.0048
Loa Loa (eye worm) hypothetical protein 0.0083 0.0435 0.0462
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0109 0.0587 0.0605
Wolbachia endosymbiont of Brugia malayi ribonuclease HI 0.0021 0.0072 0.4211
Loa Loa (eye worm) hypothetical protein 0.0037 0.0165 0.0176
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.038 0.1006
Loa Loa (eye worm) hypothetical protein 0.0083 0.0435 0.0462
Echinococcus multilocularis musashi 0.008 0.0419 0.0419
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0272 0.1551 0.1649
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0272 0.1551 0.165
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0083 0.0435 0.0435
Brugia malayi MH1 domain containing protein 0.0017 0.0046 0.0048
Loa Loa (eye worm) MH2 domain-containing protein 0.0017 0.0046 0.0048
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0083 0.0435 0.0462
Leishmania major ribonuclease H1, putative 0.0021 0.0072 0.0161
Echinococcus granulosus tm gpcr rhodopsin 0.0083 0.0435 0.0462
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0083 0.0435 0.0462
Schistosoma mansoni neuropeptide receptor 0.0083 0.0435 0.0462
Entamoeba histolytica nicotinate phosphoribosyltransferase, putative 0.0072 0.0371 0.6235
Onchocerca volvulus Protein phosphatase PP2A 55 kDa regulatory subunit homolog 0.0074 0.038 0.0404
Leishmania major hypothetical protein, conserved 0.0038 0.0173 0.0438
Echinococcus granulosus dro:myosuppressin receptor 0.0083 0.0435 0.0462
Mycobacterium ulcerans thymidylate synthase 0.0631 0.3666 1
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0034 0.0143 0.0389
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0119 0.0651
Plasmodium falciparum DNA topoisomerase 2 0.0068 0.0349 0.095
Giardia lamblia O-linked GlcNAc transferase 0.0024 0.0086 0.0472
Brugia malayi Bromodomain containing protein 0.0044 0.0202 0.0215
Echinococcus granulosus bloom syndrome protein 0.0021 0.0071 0.0075
Trypanosoma brucei hypothetical protein, conserved 0.0038 0.0173 0.047
Trypanosoma brucei RNA helicase, putative 0.0205 0.1155 0.3148
Plasmodium falciparum phd finger protein, putative 0.0028 0.0114 0.0308
Mycobacterium leprae PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) 0.0631 0.3666 1
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0034 0.0143 0.0344
Echinococcus granulosus rhodopsin orphan GPCR 0.0083 0.0435 0.0462
Trypanosoma cruzi ISWI complex protein 0.0017 0.0048 0.0098
Schistosoma mansoni smad1 5 8 and 0.0017 0.0046 0.0048
Mycobacterium ulcerans lipase LipD 0.0038 0.0173 0.0425
Schistosoma mansoni biogenic amine receptor 0.0083 0.0435 0.0462
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0068 0.0346 0.0368
Schistosoma mansoni jumonji domain containing protein 0.0074 0.0383 0.0407
Schistosoma mansoni sodium/chloride dependent transporter 0.0272 0.1551 0.1649
Loa Loa (eye worm) hypothetical protein 0.0188 0.1052 0.1119
Giardia lamblia Protein phosphatase PP2A regulatory subunit B 0.0074 0.038 1
Schistosoma mansoni Smad4 0.0017 0.0046 0.0048
Entamoeba histolytica protein phosphatase regulatory subunit, putative 0.0074 0.038 0.6401
Brugia malayi Bromodomain containing protein 0.0085 0.0448 0.0476
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0054 0.0263 0.0685
Echinococcus multilocularis G protein coupled receptor 139 0.0083 0.0435 0.0435
Mycobacterium tuberculosis Hypothetical protein 0.03 0.1716 0.4652
Loa Loa (eye worm) hypothetical protein 0.0083 0.0435 0.0462
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0119 0.0625
Schistosoma mansoni methyl-cpg binding protein mbd 0.0019 0.006 0.0064
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0213 0.0213
Onchocerca volvulus Alhambra homolog 0.0028 0.0114 0.0121
Loa Loa (eye worm) hypothetical protein 0.0053 0.0258 0.0274
Chlamydia trachomatis hypothetical protein 0.0016 0.0041 0.0139
Loa Loa (eye worm) hypothetical protein 0.0079 0.041 0.0436
Loa Loa (eye worm) hypothetical protein 0.0083 0.0435 0.0462
Echinococcus multilocularis GPCR, family 2 0.0048 0.0227 0.0227
Leishmania major trypanothione reductase 0.0097 0.0516 0.1378
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0071 0.0342
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0083 0.0435 0.0462
Loa Loa (eye worm) nuclear factor I 0.0009 0.0001 0.0001
Brugia malayi intermediate filament protein 0.008 0.0419 0.0445
Mycobacterium ulcerans hypothetical protein 0.0016 0.0041 0.0062
Echinococcus multilocularis neuropeptide Y receptor 0.0083 0.0435 0.0435
Echinococcus multilocularis somatostatin receptor 0.0083 0.0435 0.0435
Echinococcus granulosus neuropeptide receptor 0.0083 0.0435 0.0462
Loa Loa (eye worm) hypothetical protein 0.0083 0.0435 0.0462
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0109 0.0587 0.1185
Schistosoma mansoni amine GPCR 0.0083 0.0435 0.0462
Leishmania major DNA topoisomerase ii 0.0061 0.0308 0.081
Toxoplasma gondii bifunctional dihydrofolate reductase-thymidylate synthase 0.0631 0.3666 1
Schistosoma mansoni amine GPCR 0.0083 0.0435 0.0462
Loa Loa (eye worm) hypothetical protein 0.0083 0.0435 0.0462
Loa Loa (eye worm) hypothetical protein 0.0083 0.0435 0.0462
Loa Loa (eye worm) hypothetical protein 0.0019 0.006 0.0064
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0173 0.0941
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0029 0.0119 0.0106
Schistosoma mansoni hypothetical protein 0.0515 0.2982 0.3172
Schistosoma mansoni protein phosphatase pp2a regulatory subunit B 0.0074 0.038 0.0404
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0083 0.0435 0.0435
Loa Loa (eye worm) hypothetical protein 0.003 0.0124 0.0132
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0083 0.0435 0.0462
Loa Loa (eye worm) hypothetical protein 0.0151 0.0836 0.0889
Loa Loa (eye worm) serotonin transporter b 0.1603 0.9399 1
Echinococcus granulosus peregrin 0.0031 0.013 0.0138
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0038 0.0173 0.0184
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0173 0.0438
Loa Loa (eye worm) hypothetical protein 0.0083 0.0435 0.0462
Treponema pallidum nicotinate phosphoribosyltransferase 0.0072 0.0371 0.0375
Trypanosoma brucei hypothetical protein, conserved 0.0074 0.038 0.1035
Plasmodium falciparum amino acid transporter, putative 0.0272 0.1551 0.4228
Plasmodium falciparum DNA gyrase subunit A 0.0012 0.0019 0.0051
Echinococcus granulosus beta LACTamase domain containing family member 0.0038 0.0173 0.0184
Trypanosoma brucei deoxyuridine triphosphatase, putative 0.035 0.201 0.5482
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0083 0.0435 0.0462
Loa Loa (eye worm) serine/threonine protein phosphatase 2A 0.0074 0.038 0.0404
Brugia malayi hypothetical protein 0.0083 0.0435 0.0462
Loa Loa (eye worm) hypothetical protein 0.0083 0.0435 0.0462
Onchocerca volvulus 0.0083 0.0435 0.0462
Schistosoma mansoni methyl-cpg binding protein mbd 0.0019 0.006 0.0064
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0019 0.006 0.0064
Brugia malayi MH1 domain containing protein 0.0009 0.0001 0.0001
Brugia malayi neuropeptide F receptor 0.0083 0.0435 0.0462
Loa Loa (eye worm) 6-phosphofructokinase 0.0109 0.0587 0.0624
Brugia malayi Probable DNA topoisomerase II 0.0068 0.0349 0.0371
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0083 0.0435 0.0462
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0119 0.0625
Echinococcus multilocularis neuropeptide FF receptor 2 0.0083 0.0435 0.0435
Echinococcus multilocularis jumonji domain containing protein 0.004 0.0179 0.0179
Trichomonas vaginalis esterase, putative 0.0038 0.0173 0.0941
Brugia malayi Dopamine receptor protein 1 0.0083 0.0435 0.0462
Schistosoma mansoni neuropeptide receptor 0.0083 0.0435 0.0462
Echinococcus granulosus g protein coupled receptor 0.0083 0.0435 0.0462
Mycobacterium ulcerans DNA gyrase subunit A 0.0012 0.0019 0.0004
Trichomonas vaginalis glutathione reductase, putative 0.0034 0.0143 0.0768
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0151 0.0836 0.0889
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0272 0.1551 0.1649
Echinococcus multilocularis neuropeptides capa receptor 0.0083 0.0435 0.0435
Brugia malayi Serotonin receptor 0.0083 0.0435 0.0462
Trypanosoma cruzi ISWI complex protein 0.0017 0.0048 0.0098
Mycobacterium tuberculosis Probable lipase LipD 0.0038 0.0173 0.0421
Schistosoma mansoni biogenic amine receptor 0.0083 0.0435 0.0462
Trypanosoma cruzi deoxyuridine triphosphatase, putative 0.035 0.201 0.5467
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.0213 0.0226
Plasmodium falciparum nicotinate phosphoribosyltransferase, putative 0.0072 0.0371 0.1009
Loa Loa (eye worm) hypothetical protein 0.0048 0.0227 0.0242
Plasmodium vivax DNA gyrase subunit A, putative 0.0012 0.0019 0.0051
Toxoplasma gondii 6-phosphofructokinase 0.0029 0.0119 0.0324
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0083 0.0435 0.0462
Echinococcus multilocularis serotonin receptor 0.0451 0.2608 0.2608
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0034 0.0143 0.039
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0083 0.0435 0.0462
Loa Loa (eye worm) hypothetical protein 0.0083 0.0435 0.0462
Onchocerca volvulus 0.0083 0.0435 0.0462
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0083 0.0435 0.0462
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0272 0.1551 0.4229
Onchocerca volvulus 0.0272 0.1551 0.1649
Brugia malayi hypothetical protein 0.0083 0.0435 0.0462
Brugia malayi Cytochrome P450 family protein 0.0012 0.0018 0.0019
Onchocerca volvulus 0.0083 0.0435 0.0462
Echinococcus granulosus biogenic amine 5HT receptor 0.0451 0.2608 0.2775
Treponema pallidum hypothetical protein 0.0016 0.0041 0.0023
Trichomonas vaginalis phosphofructokinase, putative 0.0109 0.0587 0.3371
Brugia malayi hypothetical protein 0.0083 0.0435 0.0462
Brugia malayi jmjC domain containing protein 0.0093 0.0496 0.0527
Loa Loa (eye worm) hypothetical protein 0.0083 0.0435 0.0462
Trypanosoma brucei ISWI complex protein 0.0017 0.0048 0.013
Loa Loa (eye worm) hypothetical protein 0.0049 0.0234 0.0248
Trypanosoma cruzi nicotinate phosphoribosyltransferase, putative 0.0072 0.0371 0.098
Loa Loa (eye worm) MH1 domain-containing protein 0.0017 0.0046 0.0048
Echinococcus multilocularis G-protein coupled receptor, putative 0.0083 0.0435 0.0435
Echinococcus multilocularis neuropeptide receptor 0.0083 0.0435 0.0435
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.1603 0.9399 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0213 0.0213
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0143 0.0358
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0272 0.1551 0.1649
Echinococcus multilocularis neuropeptide Y receptor 0.0083 0.0435 0.0435
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0109 0.0587 0.1572
Echinococcus granulosus 6 phosphofructokinase 0.0109 0.0587 0.0624
Brugia malayi beta-lactamase family protein 0.0038 0.0173 0.0184
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0068 0.0349 0.0371
Treponema pallidum hypothetical protein 0.0016 0.0041 0.0023
Mycobacterium tuberculosis Probable reductase 0.0221 0.1247 0.3365
Loa Loa (eye worm) hypothetical protein 0.0083 0.0435 0.0462
Leishmania major deoxyuridine triphosphatase, putative,dUTP diphosphatase 0.035 0.201 0.5467
Loa Loa (eye worm) PHD-finger family protein 0.0023 0.0084 0.0089
Echinococcus multilocularis O glycosyltransferase 0.0041 0.0188 0.0188
Loa Loa (eye worm) G-protein coupled receptor 0.0083 0.0435 0.0462
Echinococcus granulosus neuropeptide Y receptor 0.0083 0.0435 0.0462
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0083 0.0435 0.0462
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0034 0.0143 0.0143
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0466 0.2693 0.2693
Echinococcus multilocularis rhodopsin orphan GPCR 0.0083 0.0435 0.0435
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0109 0.0587 0.1556
Treponema pallidum sodium- and chloride- dependent transporter 0.1603 0.9399 1
Onchocerca volvulus 0.0053 0.0258 0.0274
Loa Loa (eye worm) hypothetical protein 0.0083 0.0435 0.0462
Trypanosoma cruzi ribonuclease H1, putative 0.0021 0.0072 0.0161
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0034 0.0143 0.0389
Chlamydia trachomatis DNA gyrase subunit B 0.0022 0.0078 0.0386
Echinococcus granulosus fetal alzheimer antigen falz 0.0026 0.0097 0.0103
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0083 0.0435 0.0462
Trypanosoma cruzi deoxyuridine triphosphatase, putative 0.035 0.201 0.5467
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0213 0.0226
Loa Loa (eye worm) hypothetical protein 0.0083 0.0435 0.0462
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0173 0.0184
Loa Loa (eye worm) hypothetical protein 0.0083 0.0435 0.0462
Loa Loa (eye worm) hypothetical protein 0.0038 0.0173 0.0184
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0041 0.0186 0.0186
Mycobacterium tuberculosis Probable lipase LipE 0.0038 0.0173 0.0421
Echinococcus granulosus PHD finger protein rhinoceros 0.0028 0.0114 0.0121
Brugia malayi Dopamine receptor 0.0083 0.0435 0.0462
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0119 0.0323
Echinococcus multilocularis tumor protein p63 0.0361 0.2076 0.2076
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0213 0.0227
Loa Loa (eye worm) hypothetical protein 0.0039 0.0174 0.0185
Loa Loa (eye worm) hypothetical protein 0.0083 0.0435 0.0462
Entamoeba histolytica phosphofructokinase, putative 0.0109 0.0587 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0143 0.0358
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0272 0.1551 0.1649
Loa Loa (eye worm) UDP-N-acetylglucosamine-peptide N-acetylglucosaminyltransferase 0.0041 0.0187 0.0199
Schistosoma mansoni alpha-1 adrenergic receptor 0.0083 0.0435 0.0462
Echinococcus granulosus lamin dm0 0.008 0.0419 0.0446
Schistosoma mansoni bifunctional dihydrofolate reductase-thymidylate synthase 0.0631 0.3666 0.39
Echinococcus granulosus rhodopsin orphan GPCR 0.0083 0.0435 0.0462
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0173 0.0941
Echinococcus granulosus neuropeptide receptor A26 0.0561 0.3255 0.3463
Trypanosoma brucei cytochrome P450, putative 0.0012 0.0018 0.0047
Echinococcus granulosus tm gpcr rhodopsin 0.0083 0.0435 0.0462
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0034 0.0143 0.0358
Echinococcus granulosus neuropeptide Y receptor 0.0083 0.0435 0.0462
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0011 0.0013 0.0013
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0017 0.0046 0.0046
Trypanosoma cruzi protein phosphatase 2A regulatory subunit, putative 0.0074 0.038 0.1006
Trypanosoma brucei trypanothione reductase 0.0097 0.0516 0.1406
Echinococcus multilocularis fmrfamide receptor 0.0083 0.0435 0.0435
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0083 0.0435 0.0462
Loa Loa (eye worm) G-protein coupled receptor 0.0083 0.0435 0.0462
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0213 0.0227
Brugia malayi beta-lactamase 0.0038 0.0173 0.0184
Trypanosoma brucei ribonuclease H1 0.0021 0.0072 0.0194
Onchocerca volvulus 0.0038 0.0173 0.0184
Echinococcus granulosus alpha 1A adrenergic receptor 0.0083 0.0435 0.0462
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0082 0.0223
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0025 0.0091 0.0096
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0173 0.0438
Mycobacterium ulcerans 6-phosphofructokinase 0.0109 0.0587 0.1559
Schistosoma mansoni opsin-like receptor 0.0083 0.0435 0.0462
Schistosoma mansoni smad1 5 8 and 0.0017 0.0046 0.0048
Echinococcus multilocularis Smad4 0.0017 0.0046 0.0046
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0221 0.1247 0.3365
Loa Loa (eye worm) CYP4Cod1 0.0012 0.0018 0.0019
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0083 0.0435 0.0462
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0272 0.1551 0.1649
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0083 0.0435 0.0462
Loa Loa (eye worm) hypothetical protein 0.0451 0.2608 0.2774
Loa Loa (eye worm) hypothetical protein 0.0038 0.0173 0.0184
Loa Loa (eye worm) hypothetical protein 0.0083 0.0435 0.0462
Schistosoma mansoni histamine h1 receptor 0.0083 0.0435 0.0462
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0272 0.1551 0.165
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0034 0.0143 0.0358
Loa Loa (eye worm) hypothetical protein 0.0083 0.0435 0.0462
Trypanosoma brucei unspecified product 0.0023 0.0082 0.0223
Loa Loa (eye worm) hypothetical protein 0.0083 0.0435 0.0462
Echinococcus granulosus intermediate filament protein 0.008 0.0419 0.0446
Brugia malayi N-terminal motif family protein 0.0188 0.1052 0.1119
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0151 0.0836 0.0889
Chlamydia trachomatis DNA gyrase subunit B 0.0037 0.0165 0.0949
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0034 0.0143 0.0389
Echinococcus granulosus Smad4 0.0017 0.0046 0.0048
Brugia malayi beta-lactamase family protein 0.0038 0.0173 0.0184
Echinococcus multilocularis g-protein coupled receptor 0.0083 0.0435 0.0435
Schistosoma mansoni neuropeptide F-like receptor 0.0083 0.0435 0.0462
Onchocerca volvulus Neuropeptide F receptor homolog 0.0083 0.0435 0.0462
Schistosoma mansoni hypothetical protein 0.0083 0.0435 0.0462
Loa Loa (eye worm) hypothetical protein 0.0451 0.2608 0.2774
Loa Loa (eye worm) transcription factor SMAD2 0.0248 0.1409 0.1499
Treponema pallidum hypothetical protein 0.0016 0.0041 0.0023
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0083 0.0435 0.0462
Trichomonas vaginalis serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform, putative 0.0074 0.038 0.2158
Echinococcus multilocularis orexin receptor type 2 0.0083 0.0435 0.0435
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0038 0.0173 0.0421
Echinococcus granulosus tachykinin peptides receptor 99D 0.0083 0.0435 0.0462
Loa Loa (eye worm) thymidylate synthase 0.0631 0.3666 0.39
Brugia malayi Bromodomain containing protein 0.0031 0.013 0.0137
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.0114 0.0309
Brugia malayi Cytochrome P450 family protein 0.0012 0.0018 0.0019
Loa Loa (eye worm) hypothetical protein 0.0083 0.0435 0.0462
Brugia malayi PHD-finger family protein 0.0028 0.0113 0.012
Giardia lamblia O-linked GlcNAc transferase 0.0041 0.0186 0.3695
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0093 0.0496 0.0496
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0272 0.1551 0.1551
Loa Loa (eye worm) hypothetical protein 0.0046 0.0219 0.0232
Loa Loa (eye worm) beta-lactamase 0.0038 0.0173 0.0184
Brugia malayi ORL1-like opioid receptor 0.0083 0.0435 0.0462
Toxoplasma gondii DNA gyrase/topoisomerase IV, A subunit domain-containing protein 0.0012 0.0019 0.0052
Echinococcus granulosus neuropeptide receptor 0.0083 0.0435 0.0462
Brugia malayi 6-phosphofructokinase 0.0109 0.0587 0.0624
Onchocerca volvulus 0.0038 0.0173 0.0184
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0272 0.1551 0.1649
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0143 0.0358
Loa Loa (eye worm) hypothetical protein 0.0083 0.0435 0.0462
Entamoeba histolytica phosphofructokinase, putative 0.0109 0.0587 1
Brugia malayi Pre-B cell enhancing factor precursor 0.0388 0.2236 0.2379
Loa Loa (eye worm) hypothetical protein 0.0083 0.0435 0.0462
Loa Loa (eye worm) phosphofructokinase 0.0109 0.0587 0.0624
Plasmodium falciparum thioredoxin reductase 0.0034 0.0143 0.0389
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0083 0.0435 0.0435
Echinococcus multilocularis lamin 0.008 0.0419 0.0419
Schistosoma mansoni sodium/chloride dependent transporter 0.1603 0.9399 1
Loa Loa (eye worm) neuropeptide F receptor 0.0083 0.0435 0.0462
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0034 0.0143 0.0389
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0034 0.0143 0.034
Echinococcus multilocularis mothers against decapentaplegic 5 0.0017 0.0046 0.0046
Onchocerca volvulus 0.008 0.0419 0.0445
Echinococcus multilocularis fmrfamide receptor 0.0083 0.0435 0.0435
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0272 0.1551 1
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0083 0.0435 0.0462
Echinococcus granulosus neuropeptide FF receptor 2 0.0083 0.0435 0.0462
Schistosoma mansoni sodium/chloride dependent transporter 0.0272 0.1551 0.1649
Brugia malayi serine/threonine protein phosphatase 2A 0.0074 0.038 0.0404
Echinococcus granulosus microtubule associated protein 2 0.1424 0.8343 0.8876
Brugia malayi Calcitonin receptor-like protein seb-1 0.0151 0.0836 0.0889
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0034 0.0143 0.0389
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0034 0.0143 0.0358
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0083 0.0435 0.0462
Plasmodium vivax DNA topoisomerase II, putative 0.0068 0.0349 0.095
Brugia malayi hypothetical protein 0.03 0.1716 0.1825
Echinococcus multilocularis rhodopsin orphan GPCR 0.0083 0.0435 0.0435
Trypanosoma brucei DNA topoisomerase ii 0.0054 0.0263 0.0715
Echinococcus multilocularis allatostatin A receptor 0.0083 0.0435 0.0435
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0119 0.0625
Brugia malayi UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 0.0041 0.0187 0.0199
Brugia malayi G-protein coupled receptor 0.0083 0.0435 0.0462
Loa Loa (eye worm) hypothetical protein 0.0272 0.1551 0.1649
Echinococcus granulosus g protein coupled receptor 0.0083 0.0435 0.0462
Schistosoma mansoni 6-phosphofructokinase 0.0109 0.0587 0.0624
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0272 0.1551 0.1649
Loa Loa (eye worm) hypothetical protein 0.0083 0.0435 0.0462
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0272 0.1551 0.165
Trypanosoma cruzi DNA topoisomerase II, putative 0.0061 0.0308 0.081
Loa Loa (eye worm) RecQ helicase 0.0021 0.0071 0.0075
Schistosoma mansoni opsin-like receptor 0.0083 0.0435 0.0462
Echinococcus granulosus sex peptide receptor 0.0083 0.0435 0.0462
Leishmania major mitochondrial DNA topoisomerase II 0.0054 0.0263 0.0685
Echinococcus multilocularis lysine specific demethylase 5A 0.0034 0.0149 0.0149
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0083 0.0435 0.0462
Echinococcus granulosus smad 0.0017 0.0046 0.0048
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0272 0.1551 0.1551
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0083 0.0435 0.0462
Onchocerca volvulus 0.0083 0.0435 0.0462
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0034 0.0143 0.081
Brugia malayi hypothetical protein 0.0083 0.0435 0.0462
Schistosoma mansoni amine GPCR 0.0083 0.0435 0.0462
Loa Loa (eye worm) hypothetical protein 0.0083 0.0435 0.0462
Echinococcus granulosus sodium and chloride dependent glycine 0.0272 0.1551 0.165
Trichomonas vaginalis conserved hypothetical protein 0.03 0.1716 1
Brugia malayi G protein-coupled receptor 0.0083 0.0435 0.0462
Echinococcus multilocularis serotonin receptor 0.0451 0.2608 0.2608
Loa Loa (eye worm) hypothetical protein 0.0015 0.0032 0.0034
Loa Loa (eye worm) bromodomain containing protein 0.002 0.0064 0.0068
Loa Loa (eye worm) hypothetical protein 0.0272 0.1551 0.1649
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0083 0.0435 0.0462
Loa Loa (eye worm) hypothetical protein 0.0028 0.0114 0.0121
Loa Loa (eye worm) hypothetical protein 0.0015 0.0032 0.0034
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0048 0.0227 0.0227
Loa Loa (eye worm) hypothetical protein 0.0038 0.0173 0.0184
Onchocerca volvulus 0.0083 0.0435 0.0462
Schistosoma mansoni lamin 0.008 0.0419 0.0445
Schistosoma mansoni neuropeptide receptor 0.0083 0.0435 0.0462
Echinococcus granulosus rhodopsin orphan GPCR 0.0083 0.0435 0.0462
Loa Loa (eye worm) hypothetical protein 0.0083 0.0435 0.0462
Schistosoma mansoni myosin xvIII 0.0083 0.0435 0.0462
Loa Loa (eye worm) hypothetical protein 0.0037 0.0165 0.0176
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0034 0.0143 0.0389
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0221 0.1247 0.3365
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0001
Mycobacterium tuberculosis Probable dehydrogenase 0.0221 0.1247 0.3365
Brugia malayi PHD-finger family protein 0.0028 0.0114 0.0121
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0272 0.1551 0.4229
Toxoplasma gondii hypothetical protein 0.0272 0.1551 0.4229
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase, putative 0.03 0.1716 0.4661
Loa Loa (eye worm) hypothetical protein 0.0083 0.0435 0.0462
Mycobacterium tuberculosis Conserved protein 0.0038 0.0173 0.0421
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0041 0.0186 0.0198
Brugia malayi putative neuropeptide receptor 0.0083 0.0435 0.0462
Echinococcus granulosus g-protein coupled receptor 0.0083 0.0435 0.0462
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0068 0.0349 0.0371
Plasmodium vivax glutathione reductase, putative 0.0097 0.0516 0.1406
Schistosoma mansoni smad1 5 8 and 0.0017 0.0046 0.0048
Trichomonas vaginalis DNA topoisomerase II, putative 0.0068 0.0349 0.1975
Onchocerca volvulus 0.1603 0.9399 1
Loa Loa (eye worm) glutathione reductase 0.0097 0.0516 0.0549
Loa Loa (eye worm) hypothetical protein 0.0083 0.0435 0.0462
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0068 0.0349 0.0371
Brugia malayi hypothetical protein 0.0083 0.0435 0.0462
Echinococcus granulosus lysine specific demethylase 5A 0.0037 0.0162 0.0172
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0272 0.1551 0.1551
Loa Loa (eye worm) hypothetical protein 0.0046 0.0216 0.023
Loa Loa (eye worm) TYRA-2 protein 0.0083 0.0435 0.0462
Trypanosoma cruzi trypanothione reductase, putative 0.0097 0.0516 0.1378
Brugia malayi G-protein coupled receptor 0.0083 0.0435 0.0462
Schistosoma mansoni smad 0.0017 0.0046 0.0048
Onchocerca volvulus 0.0083 0.0435 0.0462
Echinococcus multilocularis smad 0.0017 0.0046 0.0046
Plasmodium vivax amine transporter, putative 0.0272 0.1551 0.4228
Treponema pallidum hypothetical protein 0.0016 0.0041 0.0023
Loa Loa (eye worm) hypothetical protein 0.1603 0.9399 1
Echinococcus granulosus nicotinamide phosphoribosyltransferase 0.0388 0.2236 0.2379
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0022 0.0078 0.4765
Echinococcus multilocularis microtubule associated protein 2 0.1424 0.8343 0.8343
Echinococcus granulosus orexin receptor type 2 0.0083 0.0435 0.0462
Loa Loa (eye worm) hypothetical protein 0.0272 0.1551 0.1649
Schistosoma mansoni phosphoglucomutase 0.0021 0.0072 0.0076
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0109 0.0587 0.1599
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0014 0.003 0.0081
Echinococcus granulosus serotonin transporter 0.1603 0.9399 1
Trypanosoma brucei protein phosphatase 2A regulatory subunit, putative 0.0074 0.038 0.1035
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0119 0.0323
Loa Loa (eye worm) hypothetical protein 0.0011 0.0013 0.0014
Echinococcus multilocularis 6 phosphofructokinase 0.0109 0.0587 0.0587
Giardia lamblia DNA topoisomerase II 0.0065 0.0331 0.8412
Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase 0.0631 0.3666 1
Loa Loa (eye worm) TOPoisomerase family member 0.0068 0.0349 0.0371
Schistosoma mansoni phosphoglucomutase 0.0021 0.0072 0.0076
Echinococcus multilocularis protein phosphatase pp2a regulatory subunit b 0.0074 0.038 0.038
Leishmania major ATP-dependent phosphofructokinase 0.0109 0.0587 0.1572
Trypanosoma cruzi trypanothione reductase, putative 0.0034 0.0143 0.0358
Brugia malayi Intermediate filament tail domain containing protein 0.008 0.0419 0.0445
Trypanosoma brucei ingi protein (ORF1) 0.0023 0.0082 0.0223
Leishmania major hypothetical protein, conserved 0.0017 0.0048 0.0098
Echinococcus granulosus sodium and chloride dependent glycine 0.0272 0.1551 0.165
Schistosoma mansoni blooms syndrome DNA helicase 0.0017 0.0045 0.0047
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0143 0.0358
Echinococcus multilocularis g protein coupled receptor 0.0083 0.0435 0.0435
Treponema pallidum NADH oxidase 0.0034 0.0143 0.0132
Trypanosoma cruzi cytochrome P450, putative 0.0012 0.0018 0.0014
Onchocerca volvulus 0.0083 0.0435 0.0462
Loa Loa (eye worm) hypothetical protein 0.0083 0.0435 0.0462
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0034 0.0143 0.0389
Brugia malayi MH1 domain containing protein 0.0017 0.0046 0.0048
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0034 0.0143 0.0358
Onchocerca volvulus 0.0272 0.1551 0.1649
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0245 0.1392 0.3763
Loa Loa (eye worm) cytochrome P450 family protein 0.0012 0.0018 0.0019
Schistosoma mansoni bromodomain containing protein 0.0072 0.037 0.0393
Schistosoma mansoni intermediate filament proteins 0.008 0.0419 0.0445
Onchocerca volvulus 0.0631 0.3666 0.39
Onchocerca volvulus 0.0038 0.0173 0.0184
Loa Loa (eye worm) hypothetical protein 0.0083 0.0435 0.0462
Echinococcus granulosus G protein coupled receptor 139 0.0083 0.0435 0.0462
Echinococcus granulosus methyl CpG binding domain protein 2 0.0019 0.006 0.0064
Loa Loa (eye worm) MH2 domain-containing protein 0.0248 0.1409 0.1499
Echinococcus granulosus rhodopsin orphan GPCR 0.0083 0.0435 0.0462
Loa Loa (eye worm) solute carrier family 6 member 4 0.1603 0.9399 1
Echinococcus granulosus fmrfamide receptor 0.0083 0.0435 0.0462
Echinococcus granulosus O glycosyltransferase 0.0041 0.0188 0.02
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0083 0.0435 0.0435
Brugia malayi G protein-coupled receptor F59B2.13 0.0083 0.0435 0.0462
Trichomonas vaginalis phosphofructokinase, putative 0.0109 0.0587 0.3371
Echinococcus granulosus tm gpcr rhodopsin 0.0083 0.0435 0.0462
Echinococcus multilocularis zinc finger protein 0.0022 0.0077 0.0077
Loa Loa (eye worm) hypothetical protein 0.0083 0.0435 0.0462
Trypanosoma cruzi ribonuclease H1, putative 0.0021 0.0072 0.0161
Echinococcus multilocularis neuropeptide receptor 0.0083 0.0435 0.0435
Echinococcus multilocularis rhodopsin orphan GPCR 0.0083 0.0435 0.0435
Loa Loa (eye worm) hypothetical protein 0.0083 0.0435 0.0462
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0022 0.0078 0.0213
Echinococcus multilocularis thioredoxin glutathione reductase 0.0097 0.0516 0.0516
Leishmania major nicotinate phosphoribosyltransferase, putative 0.0072 0.0371 0.098
Echinococcus multilocularis neuropeptide s receptor 0.0561 0.3255 0.3255
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0272 0.1551 0.165
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0034 0.0143 0.0358
Brugia malayi cytoplasmic intermediate filament protein 0.0043 0.0199 0.0212
Brugia malayi RNase H family protein 0.0021 0.0072 0.0076
Brugia malayi Thioredoxin reductase 0.0097 0.0516 0.0549
Echinococcus multilocularis thymidylate synthase 0.0631 0.3666 0.3666
Echinococcus granulosus rhodopsin orphan GPCR 0.0083 0.0435 0.0462
Brugia malayi putative neuropeptide receptor NPR1 0.0083 0.0435 0.0462
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0068 0.0349 0.0349
Schistosoma mansoni nicotinate phosphoribosyltransferase related pre-B cell enhancing factor 0.0072 0.0371 0.0394
Echinococcus multilocularis rhodopsin orphan GPCR 0.0083 0.0435 0.0435
Onchocerca volvulus 0.0083 0.0435 0.0462
Brugia malayi hypothetical protein 0.0083 0.0435 0.0462
Brugia malayi hypothetical protein 0.0272 0.1551 0.1649
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0083 0.0435 0.0462
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0034 0.0143 0.0344
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0188 0.1052 0.1119
Loa Loa (eye worm) hypothetical protein 0.008 0.0419 0.0445
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0272 0.1551 0.1649
Loa Loa (eye worm) hypothetical protein 0.0038 0.0173 0.0184
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0173 0.0941
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.001 0.0005 0.0005
Loa Loa (eye worm) cytochrome P450 family protein 0.0012 0.0018 0.0019
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0083 0.0435 0.0435
Onchocerca volvulus 0.0083 0.0435 0.0462
Trypanosoma cruzi cytochrome P450, putative 0.0012 0.0018 0.0014
Wolbachia endosymbiont of Brugia malayi hypothetical protein 0.0016 0.0041 0.1718
Schistosoma mansoni hypothetical protein 0.0083 0.0435 0.0462
Schistosoma mansoni neuropeptide receptor 0.0083 0.0435 0.0462
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0029 0.0119 0.0324
Schistosoma mansoni hypothetical protein 0.0048 0.0227 0.0242
Schistosoma mansoni hypothetical protein 0.0023 0.0084 0.0089
Schistosoma mansoni neuropeptide f receptor 76f 0.0083 0.0435 0.0462
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0022 0.0078 0.0162
Schistosoma mansoni hypothetical protein 0.0048 0.0227 0.0242
Mycobacterium tuberculosis Conserved protein 0.0038 0.0173 0.0421
Onchocerca volvulus Ribonuclease H1 homolog 0.0021 0.0072 0.0076
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0083 0.0435 0.0462
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0019 0.006 0.006
Toxoplasma gondii O-linked N-acetylglucosamine transferase 0.0041 0.0186 0.0506
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0083 0.0435 0.0462
Loa Loa (eye worm) hypothetical protein 0.0083 0.0435 0.0462
Loa Loa (eye worm) hypothetical protein 0.0272 0.1551 0.1649
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0014 0.0029 0.0079
Echinococcus granulosus rhodopsin orphan GPCR 0.0083 0.0435 0.0462
Wolbachia endosymbiont of Brugia malayi hypothetical protein 0.0016 0.0041 0.1717
Echinococcus multilocularis PHD finger protein rhinoceros 0.0028 0.0114 0.0114
Mycobacterium tuberculosis Probable oxidoreductase 0.0245 0.1392 0.3763
Toxoplasma gondii phosphofructokinase PFKII 0.0029 0.0119 0.0324
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase 0.0631 0.3666 1
Loa Loa (eye worm) latrophilin receptor protein 2 0.0048 0.0227 0.0242
Mycobacterium tuberculosis Nicotinic acid phosphoribosyltransferase PncB2 0.0072 0.0371 0.0963
Echinococcus multilocularis sodium and chloride dependent glycine 0.0272 0.1551 0.1551
Echinococcus multilocularis rhodopsin orphan GPCR 0.0083 0.0435 0.0435
Loa Loa (eye worm) norepinephrine transporter 0.1603 0.9399 1
Plasmodium vivax DNA gyrase subunit B, putative 0.0022 0.0078 0.0212
Echinococcus multilocularis lamin dm0 0.008 0.0419 0.0419
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0083 0.0435 0.0462
Echinococcus granulosus GPCR family 2 0.0048 0.0227 0.0242
Echinococcus granulosus protein phosphatase pp2a regulatory subunit b 0.0074 0.038 0.0404
Brugia malayi larval opioid receptor 0.0083 0.0435 0.0462
Brugia malayi Melatonin receptor type 1A 0.0083 0.0435 0.0462
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0213 0.0226
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0173 0.0941
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0272 0.1551 0.4229
Schistosoma mansoni biogenic amine receptor 0.0083 0.0435 0.0462
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0143 0.0358
Echinococcus granulosus thymidylate synthase 0.0631 0.3666 0.39
Brugia malayi neuropeptide F receptor 0.0083 0.0435 0.0462
Giardia lamblia NADH oxidase lateral transfer candidate 0.0034 0.0143 0.2328
Loa Loa (eye worm) hypothetical protein 0.0038 0.0173 0.0184
Brugia malayi hypothetical protein 0.0083 0.0435 0.0462
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0272 0.1551 0.1649
Schistosoma mansoni biogenic amine (5HT) receptor 0.0451 0.2608 0.2774
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0009 0.0001 0.0001
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0011 0.0013 0.0014
Schistosoma mansoni amine GPCR 0.0083 0.0435 0.0462
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0119 0.0625
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0083 0.0435 0.0435
Brugia malayi RNase H family protein 0.0021 0.0072 0.0076
Loa Loa (eye worm) hypothetical protein 0.0272 0.1551 0.1649
Plasmodium falciparum transporter, putative 0.0272 0.1551 0.4228
Giardia lamblia PHD finger protein 15 0.0028 0.0114 0.1363
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0038 0.0173 0.0421
Echinococcus granulosus neuropeptides capa receptor 0.0083 0.0435 0.0462
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.0162 0.0172
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0245 0.1392 0.3763
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0038 0.0173 0.0425
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0272 0.1551 0.1649
Echinococcus granulosus neuropeptides capa receptor 0.0083 0.0435 0.0462
Echinococcus multilocularis nicotinamide phosphoribosyltransferase 0.0388 0.2236 0.2236
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0034 0.0143 0.0152
Brugia malayi glutathione reductase 0.0097 0.0516 0.0549
Loa Loa (eye worm) hypothetical protein 0.0017 0.0046 0.0048
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0221 0.1247 0.3365
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0048 0.0227 0.0242
Onchocerca volvulus 0.008 0.0419 0.0445
Onchocerca volvulus DNA topoisomerase 2 homolog 0.005 0.0238 0.0253
Loa Loa (eye worm) hypothetical protein 0.0083 0.0435 0.0462
Onchocerca volvulus 0.0272 0.1551 0.1649
Schistosoma mansoni o-linked n-acetylglucosamine transferase ogt 0.0041 0.0188 0.02
Echinococcus multilocularis serotonin transporter 0.1603 0.9399 0.9399
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0083 0.0435 0.0462
Schistosoma mansoni hypothetical protein 0.0017 0.0048 0.0051
Brugia malayi hypothetical protein 0.0083 0.0435 0.0462
Loa Loa (eye worm) Smad1 0.0017 0.0046 0.0048
Schistosoma mansoni zinc finger protein 0.0017 0.0048 0.0051
Mycobacterium ulcerans beta-lactamase 0.0038 0.0173 0.0425
Brugia malayi MH1 domain containing protein 0.0009 0.0001 0.0001
Schistosoma mansoni neuropeptide F-like receptor 0.0083 0.0435 0.0462
Plasmodium vivax hypothetical protein, conserved 0.0272 0.1551 0.4228
Loa Loa (eye worm) hypothetical protein 0.0083 0.0435 0.0462
Echinococcus granulosus peptide allatostatin:somatostatin 0.0083 0.0435 0.0462
Trichomonas vaginalis ribonuclease H1, putative 0.0021 0.0072 0.0346
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.008 0.0419 0.0445
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0119 0.0323
Mycobacterium ulcerans DNA gyrase subunit B 0.0022 0.0078 0.0166
Loa Loa (eye worm) hypothetical protein 0.0083 0.0435 0.0462
Echinococcus granulosus hypothetical protein 0.0083 0.0435 0.0462
Leishmania major hypothetical protein, conserved 0.0074 0.038 0.1006
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0143 0.0358
Schistosoma mansoni lamin 0.008 0.0419 0.0445
Entamoeba histolytica phosphofructokinase, putative 0.0109 0.0587 1
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0034 0.0143 0.0358
Echinococcus multilocularis ribonuclease H1 0.0021 0.0072 0.0072
Echinococcus multilocularis dro:myosuppressin receptor 0.0083 0.0435 0.0435
Loa Loa (eye worm) hypothetical protein 0.008 0.0419 0.0446
Brugia malayi Sodium:neurotransmitter symporter family protein 0.1603 0.9399 1
Trypanosoma brucei dihydrofolate reductase-thymidylate synthase 0.0631 0.3666 1
Loa Loa (eye worm) hypothetical protein 0.0044 0.0203 0.0215
Echinococcus multilocularis sex peptide receptor 0.0083 0.0435 0.0435
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0034 0.0143 0.0344
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0083 0.0435 0.0462
Brugia malayi phosphofructokinase 0.0109 0.0587 0.0624
Loa Loa (eye worm) hypothetical protein 0.0272 0.1551 0.1649
Echinococcus multilocularis peregrin 0.0031 0.013 0.013
Brugia malayi PHD-finger family protein 0.0011 0.0013 0.0014
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0054 0.0263 0.0685
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0083 0.0435 0.0462
Mycobacterium tuberculosis Probable esterase LipL 0.0038 0.0173 0.0421
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0272 0.1551 0.1649
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0034 0.0143 0.0152
Trichomonas vaginalis DNA helicase recq1, putative 0.0021 0.0071 0.0342
Toxoplasma gondii thioredoxin reductase 0.0097 0.0516 0.1407
Schistosoma mansoni microtubule-associated protein tau 0.1424 0.8343 0.8876
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0173 0.0184
Schistosoma mansoni hypothetical protein 0.0083 0.0435 0.0462
Schistosoma mansoni biogenic amine (5HT) receptor 0.0466 0.2693 0.2865
Trichomonas vaginalis mercuric reductase, putative 0.0034 0.0143 0.0768
Loa Loa (eye worm) hypothetical protein 0.0272 0.1551 0.1649
Plasmodium falciparum glutathione reductase 0.0034 0.0143 0.0389
Brugia malayi hypothetical protein 0.0083 0.0435 0.0462
Onchocerca volvulus 0.0083 0.0435 0.0462
Schistosoma mansoni phosphoglucomutase 0.0021 0.0072 0.0076
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0028 0.0114 0.0121
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0083 0.0435 0.0462
Brugia malayi RNase H family protein 0.0021 0.0072 0.0076
Echinococcus multilocularis rhodopsin orphan GPCR 0.0083 0.0435 0.0435
Echinococcus multilocularis rhodopsin orphan GPCR 0.0083 0.0435 0.0435
Onchocerca volvulus 0.0083 0.0435 0.0462
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0119 0.0625
Leishmania major cytochrome p450-like protein 0.0012 0.0018 0.0014
Brugia malayi GnHR receptor homolog 0.0083 0.0435 0.0462
Mycobacterium ulcerans hypothetical protein 0.0038 0.0173 0.0425
Brugia malayi Latrophilin receptor protein 2 0.0048 0.0227 0.0242
Echinococcus granulosus jumonji domain containing protein 0.004 0.0179 0.0191
Loa Loa (eye worm) hypothetical protein 0.0083 0.0435 0.0462
Onchocerca volvulus 0.0083 0.0435 0.0462
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0026 0.0097 0.0097
Echinococcus granulosus mothers against decapentaplegic 5 0.0017 0.0046 0.0048
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0061 0.0308 0.084
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.0162 0.0172
Trypanosoma brucei nicotinate phosphoribosyltransferase, putative 0.0072 0.0371 0.1009
Brugia malayi MH2 domain containing protein 0.0017 0.0046 0.0048
Echinococcus multilocularis g protein coupled receptor 0.0083 0.0435 0.0435
Echinococcus multilocularis beta LACTamase domain containing family member 0.0038 0.0173 0.0173
Onchocerca volvulus 0.0083 0.0435 0.0462
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0097 0.0516 0.1362
Echinococcus multilocularis geminin 0.0515 0.2982 0.2982
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0083 0.0435 0.0435
Brugia malayi hypothetical protein 0.0083 0.0435 0.0462
Trypanosoma cruzi DNA topoisomerase II, putative 0.0061 0.0308 0.081
Echinococcus granulosus geminin 0.0515 0.2982 0.3173
Echinococcus multilocularis rhodopsin orphan GPCR 0.0083 0.0435 0.0435
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0083 0.0435 0.0435
Echinococcus granulosus TGF beta signal transducer SmadC 0.0017 0.0046 0.0048
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0083 0.0435 0.0462
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0039 0.0174 0.0174
Trypanosoma brucei ingi protein (ORF1) 0.0023 0.0082 0.0223
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0246 0.1396 0.3775
Loa Loa (eye worm) hypothetical protein 0.0083 0.0435 0.0462
Trichomonas vaginalis protein phosphatase pp2a regulatory subunit B, putative 0.0074 0.038 0.2158
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.0114 0.0309
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0083 0.0435 0.0462
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.005 0.0238 0.0253
Loa Loa (eye worm) melatonin receptor type 1A 0.0083 0.0435 0.0462
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0272 0.1551 0.1649
Echinococcus multilocularis sodium and chloride dependent glycine 0.0272 0.1551 0.1551
Schistosoma mansoni hypothetical protein 0.0048 0.0227 0.0242
Loa Loa (eye worm) hypothetical protein 0.003 0.0124 0.0132
Echinococcus granulosus somatostatin receptor 0.0083 0.0435 0.0462
Loa Loa (eye worm) hypothetical protein 0.0038 0.0173 0.0184
Brugia malayi follicle stimulating hormone receptor 0.0312 0.1783 0.1896
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0043 0.0199 0.0212
Onchocerca volvulus 0.0083 0.0435 0.0462
Schistosoma mansoni growth hormone secretagogue receptor 0.0083 0.0435 0.0462
Brugia malayi MH2 domain containing protein 0.0017 0.0046 0.0048
Leishmania major protein phosphatase 2A regulatory subunit, putative 0.0074 0.038 0.1006
Onchocerca volvulus 0.0083 0.0435 0.0462
Trichomonas vaginalis phosphofructokinase, putative 0.0109 0.0587 0.3371
Toxoplasma gondii ribonuclease HI protein 0.0021 0.0072 0.0195
Brugia malayi MH2 domain containing protein 0.0248 0.1409 0.1499
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0048 0.0227 0.0227

Activities

Activity type Activity value Assay description Source Reference
GI50 (functional) = 0.22 uM Reduction of tumor cell growth to 50% in Fostriecin analogues in L1210 Leukemia cell lines ChEMBL. 11881984
GI50 (functional) = 1.5 uM Reduction of tumor cell growth to 50% in Fostriecin analogues in HCT-8 colon cancer cell lines ChEMBL. 11881984

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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