Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.039 | 0.5 | 0.5 |
Echinococcus multilocularis | carboxylesterase 5A | 0.039 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.039 | 0.5 | 0.5 |
Loa Loa (eye worm) | carboxylesterase | 0.039 | 0.5 | 0.5 |
Echinococcus granulosus | acetylcholinesterase | 0.039 | 0.5 | 0.5 |
Echinococcus granulosus | acetylcholinesterase | 0.039 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.039 | 0.5 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.039 | 0.5 | 0.5 |
Echinococcus multilocularis | acetylcholinesterase | 0.039 | 0.5 | 0.5 |
Echinococcus granulosus | carboxylesterase 5A | 0.039 | 0.5 | 0.5 |
Echinococcus multilocularis | acetylcholinesterase | 0.039 | 0.5 | 0.5 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.039 | 0.5 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
MIC (functional) | = 0.03 ug ml-1 | In vitro antibacterial activity against Klebsiella X26 | ChEMBL. | 8230112 |
MIC (functional) | = 0.125 ug ml-1 | In vitro antibacterial activity against Streptococcus pneumoniae PARK | ChEMBL. | 8230112 |
MIC (functional) | = 0.125 ug ml-1 | In vitro antibacterial activity against Haemophilus influenza C.L | ChEMBL. | 8230112 |
MIC (functional) | = 0.125 ug ml-1 | In vitro antibacterial activity against E. coli EC14 | ChEMBL. | 8230112 |
MIC (functional) | = 0.125 ug ml-1 | In vitro antibacterial activity against Enterobacter aerogenes C32 | ChEMBL. | 8230112 |
MIC (functional) | = 0.125 ug ml-1 | In vitro antibacterial activity against E. coli EC14 | ChEMBL. | 8230112 |
MIC (functional) | = 8 ug ml-1 | In vitro antibacterial activity against Staphylococcus aureus X1.1 | ChEMBL. | 8230112 |
MIC (functional) | = 8 ug ml-1 | In vitro antibacterial activity against Staphylococcus epidermidis 222 | ChEMBL. | 8230112 |
MIC (functional) | > 128 ug ml-1 | In vitro antibacterial activity against Pseudomonas PS72 | ChEMBL. | 8230112 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.