Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | arachidonate 5-lipoxygenase | Starlite/ChEMBL | References |
Homo sapiens | prostaglandin E synthase | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.2154 | 1 | 0.5 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.2154 | 1 | 0.5 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.2154 | 1 | 1 |
Echinococcus granulosus | mitogen activated protein kinase | 0.2154 | 1 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.2154 | 1 | 0.5 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0142 | 0.0209 | 0.0036 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.2154 | 1 | 0.5 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.2154 | 1 | 1 |
Schistosoma mansoni | membrane associated proteins in eicosanoid and glutathione metabolism family member | 0.059 | 0.2386 | 0.2386 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.2154 | 1 | 0.5 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.2154 | 1 | 1 |
Trypanosoma brucei | protein kinase, putative | 0.2154 | 1 | 0.5 |
Giardia lamblia | Kinase, CMGC MAPK | 0.2154 | 1 | 0.5 |
Schistosoma mansoni | serine/threonine protein kinase | 0.2154 | 1 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.2154 | 1 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.2154 | 1 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.2154 | 1 | 0.5 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.2154 | 1 | 0.5 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.2154 | 1 | 0.5 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0142 | 0.0209 | 0.0036 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.2154 | 1 | 0.5 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.2154 | 1 | 0.5 |
Schistosoma mansoni | microsomal glutathione s-transferase | 0.0135 | 0.0173 | 0.0173 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.2154 | 1 | 1 |
Schistosoma mansoni | lipoxygenase | 0.0142 | 0.0209 | 0.0209 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.