TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 258.229 | Formula: C13H10N2O4
H donors: 1 H acceptors: 5 LogP: 0.86 Rotable bonds: 4
Rule of 5 violations (Lipinski): 1
SMILES: COC(=O)c1ccnc(c1)c1nccc(c1)C(=O)O
InChi: 1S/C13H10N2O4/c1-19-13(18)9-3-5-15-11(7-9)10-6-8(12(16)17)2-4-14-10/h2-7H,1H3,(H,16,17)
InChiKey: GDIPAQOCWAFNMZ-UHFFFAOYSA-N

Network

Hover on a compound node to display the structore

Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

This is a work in progress. Come back soon to try this features!

Clustering layers

This is a work in progress. Come back soon to try this features!

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species	Target name	Source	Bibliographic reference
Homo sapiens	lysine (K)-specific demethylase 5C	Starlite/ChEMBL	References
Homo sapiens	lysine (K)-specific demethylase 3A	Starlite/ChEMBL	References
Homo sapiens	lysine (K)-specific demethylase 6B	Starlite/ChEMBL	References
Homo sapiens	lysine (K)-specific demethylase 4C	Starlite/ChEMBL	References
Homo sapiens	lysine (K)-specific demethylase 2A	Starlite/ChEMBL	References
Homo sapiens	lysine (K)-specific demethylase 4E	Starlite/ChEMBL	References

Predicted pathogen targets for this compound

By orthology

Species	Potential target	Known druggable target/s	Ortholog Group
Brugia malayi	jmjC domain containing protein	Get druggable targets OG5_129024	All targets in OG5_129024
Loa Loa (eye worm)	jmjC domain-containing protein	Get druggable targets OG5_127917	All targets in OG5_127917
Schistosoma mansoni	jumonji/arid domain-containing protein	Get druggable targets OG5_127370	All targets in OG5_127370
Schistosoma japonicum	Ubiquitously transcribed X chromosome tetratricopeptide repeat protein, putative	Get druggable targets OG5_128428	All targets in OG5_128428
Echinococcus granulosus	jumonji domain containing protein	Get druggable targets OG5_127917	All targets in OG5_127917
Brugia malayi	jmjC domain containing protein	Get druggable targets OG5_127917	All targets in OG5_127917
Brugia malayi	jmjC domain containing protein	Get druggable targets OG5_128428	All targets in OG5_128428
Candida albicans	similar to S. cerevisiae YER051W	Get druggable targets OG5_129555	All targets in OG5_129555
Loa Loa (eye worm)	hypothetical protein	Get druggable targets OG5_128428	All targets in OG5_128428
Schistosoma mansoni	jumonji/arid domain-containing protein	Get druggable targets OG5_127370	All targets in OG5_127370
Candida albicans	one of two closely related potential jumonji-like transcription factor genes similar to S. cerevisiae RPH1 (YER169W) damage-resp	Get druggable targets OG5_127917	All targets in OG5_127917
Schistosoma japonicum	IPR011011,Zinc finger, FYVE/PHD-type,domain-containing	Get druggable targets OG5_127370	All targets in OG5_127370
Babesia bovis	jmjC transcription factor, putative	Get druggable targets OG5_127370	All targets in OG5_127370
Schistosoma mansoni	jumonji domain containing protein	Get druggable targets OG5_127917	All targets in OG5_127917
Trichomonas vaginalis	O-linked N-acetylglucosamine transferase, ogt, putative	Get druggable targets OG5_128428	All targets in OG5_128428
Candida albicans	General repressor of transcription	Get druggable targets OG5_128428	All targets in OG5_128428
Schistosoma japonicum	Probable JmjC domain-containing histone demethylation protein 3B, putative	Get druggable targets OG5_127917	All targets in OG5_127917
Brugia malayi	jmjC domain containing protein	Get druggable targets OG5_129555	All targets in OG5_129555
Echinococcus multilocularis	Transcription factor, JmjC domain containing protein	Get druggable targets OG5_127917	All targets in OG5_127917
Loa Loa (eye worm)	hypothetical protein	Get druggable targets OG5_127917	All targets in OG5_127917
Candida albicans	one of two closely related potential jumonji-like transcription factor genes similar to S. cerevisiae RPH1 (YER169W) damage-resp	Get druggable targets OG5_127917	All targets in OG5_127917
Echinococcus multilocularis	jumonji domain containing 1A	Get druggable targets OG5_129024	All targets in OG5_129024
Trichomonas vaginalis	O-linked N-acetylglucosamine transferase, ogt, putative	Get druggable targets OG5_128428	All targets in OG5_128428
Schistosoma japonicum	expressed protein	Get druggable targets OG5_127917	All targets in OG5_127917
Echinococcus granulosus	jumonji domain containing 1A	Get druggable targets OG5_129024	All targets in OG5_129024
Echinococcus granulosus	lysine specific demethylase 5A	Get druggable targets OG5_127370	All targets in OG5_127370
Echinococcus granulosus	Transcription factor JmjC domain containing protein	Get druggable targets OG5_127917	All targets in OG5_127917
Trichomonas vaginalis	conserved hypothetical protein	Get druggable targets OG5_128428	All targets in OG5_128428
Schistosoma mansoni	jumonji domain containing protein	Get druggable targets OG5_129024	All targets in OG5_129024
Trichomonas vaginalis	O-linked N-acetylglucosamine transferase, ogt, putative	Get druggable targets OG5_128428	All targets in OG5_128428
Trichomonas vaginalis	O-linked N-acetylglucosamine transferase, ogt, putative	Get druggable targets OG5_128428	All targets in OG5_128428
Neospora caninum	hypothetical protein	Get druggable targets OG5_127370	All targets in OG5_127370
Echinococcus multilocularis	lysine specific demethylase 5A	Get druggable targets OG5_127370	All targets in OG5_127370
Candida albicans	one of two closely related potential jumonji-like transcription factor genes similar to S. cerevisiae RPH1 (YER169W) damage-resp	Get druggable targets OG5_127917	All targets in OG5_127917
Schistosoma japonicum	Histone demethylase rbr-2, putative	Get druggable targets OG5_127370	All targets in OG5_127370
Brugia malayi	jmjC domain containing protein	Get druggable targets OG5_129555	All targets in OG5_129555
Candida albicans	similar to S. cerevisiae YJR119C	Get druggable targets OG5_127370	All targets in OG5_127370
Loa Loa (eye worm)	jmjC domain-containing protein	Get druggable targets OG5_129024	All targets in OG5_129024
Echinococcus granulosus	Jumonji AT rich interactive domain 1B	Get druggable targets OG5_127370	All targets in OG5_127370
Trichomonas vaginalis	O-linked N-acetylglucosamine transferase, ogt, putative	Get druggable targets OG5_128428	All targets in OG5_128428
Brugia malayi	jmjC domain containing protein	Get druggable targets OG5_127370	All targets in OG5_127370
Loa Loa (eye worm)	jmjC domain-containing protein	Get druggable targets OG5_127370	All targets in OG5_127370
Trichomonas vaginalis	conserved hypothetical protein	Get druggable targets OG5_128428	All targets in OG5_128428
Trichomonas vaginalis	conserved hypothetical protein	Get druggable targets OG5_128428	All targets in OG5_128428
Candida albicans	similar to S. cerevisiae YER051W	Get druggable targets OG5_129555	All targets in OG5_129555
Echinococcus multilocularis	jumonji domain containing protein	Get druggable targets OG5_127917	All targets in OG5_127917
Loa Loa (eye worm)	hypothetical protein	Get druggable targets OG5_129555	All targets in OG5_129555
Schistosoma japonicum	JmjC domain-containing histone demethylation protein 3C, putative	Get druggable targets OG5_127917	All targets in OG5_127917
Schistosoma japonicum	hypothetical protein	Get druggable targets OG5_128428	All targets in OG5_128428
Echinococcus multilocularis	lysine specific demethylase 6a	Get druggable targets OG5_128428	All targets in OG5_128428
Trichomonas vaginalis	O-linked N-acetylglucosamine transferase, ogt, putative	Get druggable targets OG5_128428	All targets in OG5_128428
Trichomonas vaginalis	O-linked N-acetylglucosamine transferase, ogt, putative	Get druggable targets OG5_128428	All targets in OG5_128428
Candida albicans	one of two closely related potential jumonji-like transcription factor genes similar to S. cerevisiae RPH1 (YER169W) damage-resp	Get druggable targets OG5_127917	All targets in OG5_127917
Loa Loa (eye worm)	hypothetical protein	Get druggable targets OG5_128428	All targets in OG5_128428
Schistosoma japonicum	expressed protein	Get druggable targets OG5_127370	All targets in OG5_127370
Toxoplasma gondii	histone lysine demethylase JMJC1/KDM5D/JARID1D	Get druggable targets OG5_127370	All targets in OG5_127370
Schistosoma mansoni	ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related	Get druggable targets OG5_128428	All targets in OG5_128428
Toxoplasma gondii	hypothetical protein	Get druggable targets OG5_127370	All targets in OG5_127370
Candida albicans	General repressor of transcription	Get druggable targets OG5_128428	All targets in OG5_128428
Candida albicans	similar to S. cerevisiae YJR119C	Get druggable targets OG5_127370	All targets in OG5_127370
Schistosoma japonicum	expressed protein	Get druggable targets OG5_127917	All targets in OG5_127917
Entamoeba histolytica	hypothetical protein, conserved	Get druggable targets OG5_128428	All targets in OG5_128428
Echinococcus multilocularis	Jumonji, AT rich interactive domain 1B	Get druggable targets OG5_127370	All targets in OG5_127370
Loa Loa (eye worm)	hypothetical protein	Get druggable targets OG5_128428	All targets in OG5_128428
Trichomonas vaginalis	conserved hypothetical protein	Get druggable targets OG5_128428	All targets in OG5_128428
Echinococcus granulosus	lysine specific demethylase 6a	Get druggable targets OG5_128428	All targets in OG5_128428
Plasmodium yoelii	hypothetical protein	Get druggable targets OG5_127917	All targets in OG5_127917

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Loa Loa (eye worm)	TK/FER protein kinase	0.0486	0.3266	1
Echinococcus multilocularis	TRP (transient receptor potential) channel	0.0088	0.0195	0.0195
Echinococcus granulosus	potassium channel KvQLT family member kqt 1	0.0088	0.0195	0.0195
Plasmodium vivax	tyrosine kinase-like protein, putative	0.0486	0.3266	1
Echinococcus multilocularis	tyrosine protein kinase lyn tyrosine protein kinase blk	0.0486	0.3266	0.3266
Loa Loa (eye worm)	hypothetical protein	0.0088	0.0195	0.0368
Echinococcus multilocularis	transient receptor potential gamma protein	0.0088	0.0195	0.0195
Loa Loa (eye worm)	hypothetical protein	0.0088	0.0195	0.0368
Echinococcus granulosus	transient receptor potential gamma protein	0.0088	0.0195	0.0195
Echinococcus multilocularis	sodium leak channel non selective protein	0.0088	0.0195	0.0195
Echinococcus granulosus	potassium voltage gated channel subfamily D	0.0088	0.0195	0.0195
Echinococcus multilocularis	transient receptor potential cation channel	0.0088	0.0195	0.0195
Loa Loa (eye worm)	hypothetical protein	0.0486	0.3266	1
Toxoplasma gondii	calcium dependent protein kinase CDPK8	0.0486	0.3266	1
Brugia malayi	Protein kinase domain containing protein	0.0486	0.3266	1
Plasmodium falciparum	tyrosine kinase-like protein	0.0486	0.3266	1
Schistosoma mansoni	voltage-gated potassium channel	0.0088	0.0195	0.0596
Brugia malayi	Protein kinase domain containing protein	0.0486	0.3266	1
Schistosoma mansoni	calcium channel voltage-dependent p/q type alpha 1a-related	0.0088	0.0195	0.0596
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0486	0.3266	1
Brugia malayi	Guanylyl cyclase protein 23	0.0486	0.3266	1
Trichomonas vaginalis	ankyrin repeat-containing protein, putative	0.0486	0.3266	1
Echinococcus granulosus	tyrosine protein kinase Srms	0.0486	0.3266	0.3266
Schistosoma mansoni	tyrosine kinase	0.0486	0.3266	1
Trichomonas vaginalis	TKL family protein kinase	0.0486	0.3266	1
Echinococcus granulosus	cyclic nucleotide gated cation channel	0.0088	0.0195	0.0195
Loa Loa (eye worm)	hypothetical protein	0.0486	0.3266	1
Schistosoma mansoni	voltage-gated potassium channel	0.0088	0.0195	0.0596
Echinococcus multilocularis	cyclic nucleotide gated cation channel alpha 3	0.0088	0.0195	0.0195
Echinococcus multilocularis	voltage dependent L type calcium channel subunit	0.0088	0.0195	0.0195
Echinococcus granulosus	tyrosine protein kinase Fps85D	0.0486	0.3266	0.3266
Echinococcus granulosus	tyrosine protein kinase Btk29A	0.0486	0.3266	0.3266
Echinococcus granulosus	epidermal growth factor receptor	0.0486	0.3266	0.3266
Trichomonas vaginalis	TKL family protein kinase	0.0486	0.3266	1
Trichomonas vaginalis	TKL family protein kinase	0.0486	0.3266	1
Brugia malayi	Protein kinase domain containing protein	0.0486	0.3266	1
Brugia malayi	Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit	0.0088	0.0195	0.0338
Schistosoma mansoni	voltage-gated potassium channel	0.0088	0.0195	0.0596
Echinococcus multilocularis	transient receptor potential cation channel	0.0088	0.0195	0.0195
Brugia malayi	Tyrosine-protein kinase abl-1	0.0486	0.3266	1
Brugia malayi	Raf kinase	0.0486	0.3266	1
Loa Loa (eye worm)	cyclic-nucleotide gated cation channel	0.0088	0.0195	0.0368
Brugia malayi	Protein kinase domain containing protein	0.0486	0.3266	1
Loa Loa (eye worm)	TK/FER protein kinase	0.0486	0.3266	1
Echinococcus multilocularis	potassium voltage gated channel subfamily H	0.0088	0.0195	0.0195
Echinococcus granulosus	voltage gated sodium channel Nav1 alpha subunit	0.1359	1	1
Echinococcus granulosus	hyperpolarization activated cyclic	0.0088	0.0195	0.0195
Loa Loa (eye worm)	TK/DDR protein kinase	0.0486	0.3266	1
Echinococcus granulosus	Potassium voltage gated channel protein Shaw	0.0088	0.0195	0.0195
Echinococcus granulosus	tyrosine kinase\|tyrosine protein kinase Fyn	0.0486	0.3266	0.3266
Loa Loa (eye worm)	TK/FER protein kinase	0.0486	0.3266	1
Echinococcus multilocularis	tyrosine protein kinase Src42A	0.0486	0.3266	0.3266
Loa Loa (eye worm)	TKL/MLK/HH498 protein kinase	0.0486	0.3266	1
Onchocerca volvulus		0.0486	0.3266	1
Trypanosoma cruzi	STE/STE11 serine/threonine-protein kinase, putative	0.0486	0.3266	1
Trichomonas vaginalis	TKL family protein kinase	0.0486	0.3266	1
Loa Loa (eye worm)	TK/FAK protein kinase	0.0486	0.3266	1
Trichomonas vaginalis	TKL family protein kinase	0.0486	0.3266	1
Echinococcus granulosus	two pore calcium channel protein 2	0.0088	0.0195	0.0195
Brugia malayi	Furin-like cysteine rich region family protein	0.0486	0.3266	1
Echinococcus granulosus	cyclic nucleotide gated cation channel alpha 3	0.0088	0.0195	0.0195
Echinococcus granulosus	dual specificity testis-specific protein kinase	0.0486	0.3266	0.3266
Schistosoma mansoni	voltage-gated potassium channel	0.0088	0.0195	0.0596
Schistosoma mansoni	transient receptor potential channel	0.0088	0.0195	0.0596
Trichomonas vaginalis	conserved hypothetical protein	0.0486	0.3266	1
Echinococcus multilocularis	protein tyrosine kinase	0.0486	0.3266	0.3266
Echinococcus multilocularis	Jumonji, AT rich interactive domain 1B	0.0207	0.1115	0.1115
Trichomonas vaginalis	br serine/threonine-protein kinase, putative	0.0486	0.3266	1
Echinococcus multilocularis	two pore calcium channel protein 2	0.0088	0.0195	0.0195
Loa Loa (eye worm)	TKL/MLK/TAK1 protein kinase	0.0486	0.3266	1
Trypanosoma brucei	JmjC domain, hydroxylase, putative	0.0095	0.0251	0.0185
Trichomonas vaginalis	TKL family protein kinase	0.0486	0.3266	1
Trichomonas vaginalis	TKL family protein kinase	0.0486	0.3266	1
Brugia malayi	hypothetical protein	0.0486	0.3266	1
Leishmania major	protein kinase, putative	0.0486	0.3266	0.3133
Schistosoma mansoni	tyrosine protein kinase fes (fps) (ptk group IV)	0.0486	0.3266	1
Schistosoma mansoni	transient receptor potential channel	0.0088	0.0195	0.0596
Schistosoma mansoni	protein tyrosine kinase	0.0486	0.3266	1
Echinococcus granulosus	sodium leak channel non selective protein	0.0088	0.0195	0.0195
Echinococcus granulosus	raf serine:threonine protein kinase	0.0486	0.3266	0.3266
Trichomonas vaginalis	TKL family protein kinase	0.0486	0.3266	1
Trichomonas vaginalis	TKL family protein kinase	0.0486	0.3266	1
Onchocerca volvulus		0.0486	0.3266	1
Echinococcus granulosus	potassium voltage gated channel protein	0.0088	0.0195	0.0195
Echinococcus multilocularis	tyrosine protein kinase transmembrane receptor	0.0486	0.3266	0.3266
Loa Loa (eye worm)	TK/KIN6 protein kinase	0.0486	0.3266	1
Trypanosoma brucei	Pseudokinase, putative	0.0486	0.3266	1
Echinococcus multilocularis	lysine specific demethylase 6a	0.0136	0.0565	0.0565
Brugia malayi	Protein kinase domain containing protein	0.0486	0.3266	1
Echinococcus multilocularis	fibroblast growth factor receptor 4	0.0486	0.3266	0.3266
Trichomonas vaginalis	AGC family protein kinase	0.0486	0.3266	1
Loa Loa (eye worm)	hypothetical protein	0.0486	0.3266	1
Loa Loa (eye worm)	hypothetical protein	0.0486	0.3266	1
Trichomonas vaginalis	TKL family protein kinase	0.0486	0.3266	1
Trichomonas vaginalis	protein kinase atn1, putative	0.0486	0.3266	1
Echinococcus granulosus	tyrosine protein kinase Blk	0.0486	0.3266	0.3266
Schistosoma mansoni	voltage-gated potassium channel	0.0088	0.0195	0.0596
Echinococcus multilocularis	dual specificity testis specific protein kinase	0.0486	0.3266	0.3266
Schistosoma mansoni	jumonji domain containing protein	0.0188	0.0965	0.2953
Echinococcus granulosus	tyrosine protein kinase Src64B	0.0486	0.3266	0.3266
Echinococcus multilocularis	potassium voltage gated channel subfamily D	0.0088	0.0195	0.0195
Trichomonas vaginalis	TKL family protein kinase	0.0486	0.3266	1
Trichomonas vaginalis	TKL family protein kinase	0.0486	0.3266	1
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0486	0.3266	0.3266
Echinococcus granulosus	3'partial\|retinal guanylyl cyclase 2	0.0486	0.3266	0.3266
Trichomonas vaginalis	TKL family protein kinase	0.0486	0.3266	1
Trichomonas vaginalis	TKL family protein kinase	0.0486	0.3266	1
Brugia malayi	Protein kinase domain containing protein	0.0486	0.3266	1
Schistosoma mansoni	protein kinase	0.0486	0.3266	1
Trichomonas vaginalis	TKL family protein kinase	0.0486	0.3266	1
Loa Loa (eye worm)	calcium channel	0.0088	0.0195	0.0368
Toxoplasma gondii	STE kinase	0.0486	0.3266	1
Loa Loa (eye worm)	TK/Met protein kinase	0.0486	0.3266	1
Trichomonas vaginalis	TKL family protein kinase	0.0486	0.3266	1
Loa Loa (eye worm)	TK/CSK protein kinase	0.0486	0.3266	1
Schistosoma mansoni	tyrosine-protein kinase fps85d	0.0486	0.3266	1
Echinococcus multilocularis	potassium voltage gated channel subfamily D	0.0088	0.0195	0.0195
Onchocerca volvulus		0.0486	0.3266	1
Trichomonas vaginalis	CAMK family protein kinase	0.0486	0.3266	1
Trypanosoma brucei	AGC/RSK family serine/threonine kinase, putative	0.0486	0.3266	1
Echinococcus granulosus	potassium voltage gated channel subfamily H	0.0088	0.0195	0.0195
Schistosoma mansoni	voltage-gated potassium channel	0.0088	0.0195	0.0596
Brugia malayi	Receptor family ligand binding region containing protein	0.0486	0.3266	1
Echinococcus multilocularis	voltage dependent calcium channel type d subunit	0.0088	0.0195	0.0195
Echinococcus multilocularis	sodium channel protein	0.1359	1	1
Schistosoma mansoni	phd/f-box containing protein	0.0095	0.0251	0.0769
Echinococcus granulosus	mitogen activated protein kinase kinase kinase	0.0486	0.3266	0.3266
Onchocerca volvulus		0.0486	0.3266	1
Loa Loa (eye worm)	hypothetical protein	0.0088	0.0195	0.0368
Echinococcus granulosus	kinase suppressor of Ras 1	0.0486	0.3266	0.3266
Brugia malayi	Protein kinase domain containing protein	0.0486	0.3266	1
Echinococcus multilocularis	tyrosine protein kinase pr2	0.0486	0.3266	0.3266
Brugia malayi	hypothetical protein	0.0486	0.3266	1
Loa Loa (eye worm)	TK protein kinase	0.0486	0.3266	1
Schistosoma mansoni	serine/threonine protein kinase	0.0486	0.3266	1
Brugia malayi	bone morphogenetic protein type 1 receptor	0.0486	0.3266	1
Trichomonas vaginalis	TKL family protein kinase	0.0486	0.3266	1
Loa Loa (eye worm)	TK/FER protein kinase	0.0486	0.3266	1
Schistosoma mansoni	two-pore calcium channel	0.0088	0.0195	0.0596
Echinococcus granulosus	transient receptor potential cation channel	0.0088	0.0195	0.0195
Trichomonas vaginalis	conserved hypothetical protein	0.0486	0.3266	1
Loa Loa (eye worm)	TK protein kinase	0.0486	0.3266	1
Loa Loa (eye worm)	hypothetical protein	0.0486	0.3266	1
Echinococcus granulosus	transient receptor potential cation channel	0.0088	0.0195	0.0195
Echinococcus multilocularis	epidermal growth factor receptor	0.0486	0.3266	0.3266
Brugia malayi	jmjC domain containing protein	0.0188	0.0965	0.276
Loa Loa (eye worm)	cyclic-nucleotide gated cation channel	0.0088	0.0195	0.0368
Giardia lamblia	Kinase, NEK	0.0486	0.3266	0.5
Loa Loa (eye worm)	hypothetical protein	0.0088	0.0195	0.0368
Loa Loa (eye worm)	TK/FER protein kinase	0.0486	0.3266	1
Loa Loa (eye worm)	hypothetical protein	0.0088	0.0195	0.0368
Echinococcus granulosus	potassium voltage gated channel subfamily A	0.0088	0.0195	0.0195
Trichomonas vaginalis	TKL family protein kinase	0.0486	0.3266	1
Schistosoma mansoni	tyrosine kinase	0.0486	0.3266	1
Echinococcus granulosus	voltage gated potassium channel	0.0088	0.0195	0.0195
Entamoeba histolytica	protein kinase, putative	0.0541	0.3694	1
Loa Loa (eye worm)	TKL/MLK/ILK protein kinase	0.0486	0.3266	1
Loa Loa (eye worm)	hypothetical protein	0.0486	0.3266	1
Echinococcus granulosus	potassium voltage gated channel protein	0.0088	0.0195	0.0195
Leishmania major	hypothetical protein, conserved	0.0095	0.0251	0.0058
Echinococcus multilocularis	potassium voltage gated channel protein	0.0088	0.0195	0.0195
Echinococcus granulosus	retinal guanylyl cyclase 2	0.0486	0.3266	0.3266
Echinococcus granulosus	tyrosine protein kinase csk	0.0486	0.3266	0.3266
Entamoeba histolytica	hypothetical protein	0.0541	0.3694	1
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0486	0.3266	0.3266
Brugia malayi	Protein kinase domain containing protein	0.0486	0.3266	1
Loa Loa (eye worm)	voltage-gated calcium channel	0.0088	0.0195	0.0368
Schistosoma mansoni	protein kinase	0.0486	0.3266	1
Loa Loa (eye worm)	hypothetical protein	0.0088	0.0195	0.0368
Schistosoma mansoni	tyrosine kinase	0.0486	0.3266	1
Loa Loa (eye worm)	TK/EGFR protein kinase	0.0486	0.3266	1
Echinococcus granulosus	voltage gated potassium channel	0.0088	0.0195	0.0195
Echinococcus multilocularis	tyrosine protein kinase Src64B	0.0486	0.3266	0.3266
Trichomonas vaginalis	TKL family protein kinase	0.0486	0.3266	1
Echinococcus multilocularis	voltage gated potassium channel	0.0088	0.0195	0.0195
Echinococcus multilocularis	voltage dependent calcium channel type d subunit	0.0088	0.0195	0.0195
Echinococcus granulosus	potassium voltage gated channel subfamily C	0.0088	0.0195	0.0195
Echinococcus multilocularis	raf serine:threonine protein kinase	0.0486	0.3266	0.3266
Trichomonas vaginalis	TKL family protein kinase	0.0486	0.3266	1
Trichomonas vaginalis	STE family protein kinase	0.0486	0.3266	1
Schistosoma mansoni	jumonji/arid domain-containing protein	0.0265	0.1563	0.4786
Echinococcus multilocularis	transfer RNA-Thr	0.0486	0.3266	0.3266
Echinococcus granulosus	potassium voltage gated channel subfamily D	0.0088	0.0195	0.0195
Loa Loa (eye worm)	hypothetical protein	0.0088	0.0195	0.0368
Echinococcus multilocularis	transient receptor potential cation channel	0.0088	0.0195	0.0195
Brugia malayi	Tyrosine-protein kinase PR2	0.0486	0.3266	1
Echinococcus granulosus	transient receptor potential cation channel	0.0088	0.0195	0.0195
Echinococcus multilocularis	insulin growth factor 1 receptor beta	0.0486	0.3266	0.3266
Leishmania major	hypothetical protein, conserved	0.0486	0.3266	0.3133
Schistosoma mansoni	tyrosine kinase	0.0486	0.3266	1
Brugia malayi	Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog	0.0088	0.0195	0.0338
Schistosoma mansoni	ephrin receptor	0.0486	0.3266	1
Echinococcus granulosus	transient receptor potential cation channel	0.0088	0.0195	0.0195
Echinococcus multilocularis	receptor type guanylyl cyclase	0.0486	0.3266	0.3266
Echinococcus granulosus	tyrosine protein kinase ABL1	0.0486	0.3266	0.3266
Trichomonas vaginalis	TKL family protein kinase	0.0486	0.3266	1
Trichomonas vaginalis	TKL family protein kinase	0.0486	0.3266	1
Brugia malayi	SH2 domain containing protein	0.0486	0.3266	1
Brugia malayi	protein-tyrosine kinase	0.0486	0.3266	1
Echinococcus granulosus	epidermal growth factor receptor	0.0486	0.3266	0.3266
Brugia malayi	Protein kinase domain containing protein	0.0486	0.3266	1
Trichomonas vaginalis	TKL family protein kinase	0.0486	0.3266	1
Loa Loa (eye worm)	TK protein kinase	0.0486	0.3266	1
Echinococcus granulosus	cyclic nucleotide gated cation channel	0.0088	0.0195	0.0195
Echinococcus multilocularis	tyrosine protein kinase Fps85D	0.0486	0.3266	0.3266
Echinococcus granulosus	activated cdc42 kinase 1	0.0486	0.3266	0.3266
Schistosoma mansoni	proto-oncogene tyrosine-protein kinase src	0.0486	0.3266	1
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0486	0.3266	0.3266
Trichomonas vaginalis	TKL family protein kinase	0.0486	0.3266	1
Loa Loa (eye worm)	protein kinase domain-containing protein	0.0486	0.3266	1
Brugia malayi	Protein kinase domain containing protein	0.0486	0.3266	1
Trichomonas vaginalis	TKL family protein kinase	0.0486	0.3266	1
Echinococcus multilocularis	tyrosine protein kinase Fes:Fps	0.0486	0.3266	0.3266
Leishmania major	protein kinase, putative	0.0486	0.3266	0.3133
Schistosoma mansoni	serine/threonine protein kinase	0.0486	0.3266	1
Echinococcus granulosus	activated cdc42 kinase 1	0.0486	0.3266	0.3266
Trichomonas vaginalis	TKL family protein kinase	0.0486	0.3266	1
Loa Loa (eye worm)	hypothetical protein	0.0486	0.3266	1
Loa Loa (eye worm)	TK protein kinase	0.0486	0.3266	1
Brugia malayi	Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog	0.0088	0.0195	0.0338
Onchocerca volvulus		0.0486	0.3266	1
Echinococcus granulosus	transient receptor potential cation channel	0.0088	0.0195	0.0195
Onchocerca volvulus		0.0486	0.3266	1
Brugia malayi	SRC-1	0.0486	0.3266	1
Onchocerca volvulus		0.0486	0.3266	1
Echinococcus granulosus	tyrosine protein kinase	0.0486	0.3266	0.3266
Loa Loa (eye worm)	voltage-dependent calcium channel	0.0088	0.0195	0.0368
Loa Loa (eye worm)	TKL/STKR/TYPE1 protein kinase	0.0486	0.3266	1
Brugia malayi	olfactory channel protein osm-9	0.0088	0.0195	0.0338
Echinococcus multilocularis	activated cdc42 kinase 1	0.0486	0.3266	0.3266
Echinococcus granulosus	basic fibroblast growth factor receptor 1 A	0.0486	0.3266	0.3266
Schistosoma mansoni	tyrosine kinase	0.0486	0.3266	1
Trichomonas vaginalis	TKL family protein kinase	0.0486	0.3266	1
Echinococcus granulosus	tyrosine protein kinase csk	0.0486	0.3266	0.3266
Schistosoma mansoni	tyrosine kinase	0.0486	0.3266	1
Brugia malayi	Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog	0.0088	0.0195	0.0338
Echinococcus granulosus	calcium activated potassium channel	0.0088	0.0195	0.0195
Echinococcus granulosus	voltage gated hydrogen channel 1	0.0088	0.0195	0.0195
Echinococcus multilocularis	voltage gated hydrogen channel 1	0.0088	0.0195	0.0195
Echinococcus multilocularis	tyrosine protein kinase Fgr	0.0486	0.3266	0.3266
Echinococcus granulosus	transient receptor potential cation channel	0.0088	0.0195	0.0195
Trichomonas vaginalis	serine/threonine-protein kinase wnk, putative	0.0486	0.3266	1
Loa Loa (eye worm)	hypothetical protein	0.0088	0.0195	0.0368
Echinococcus multilocularis	kinase suppressor of Ras 1	0.0486	0.3266	0.3266
Schistosoma mansoni	hyperpolarization activated cyclic nucleotide-gated potassium channel	0.0088	0.0195	0.0596
Echinococcus granulosus	ryanodine receptor 44f	0.0088	0.0195	0.0195
Echinococcus multilocularis	ryanodine receptor 44f	0.0088	0.0195	0.0195
Brugia malayi	Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog	0.0088	0.0195	0.0338
Schistosoma mansoni	tyrosine kinase	0.0486	0.3266	1
Trichomonas vaginalis	TKL family protein kinase	0.0486	0.3266	1
Trichomonas vaginalis	TKL family protein kinase	0.0486	0.3266	1
Brugia malayi	Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog	0.0088	0.0195	0.0338
Plasmodium vivax	protein kinase, putative	0.0486	0.3266	1
Toxoplasma gondii	Tyrosine kinase-like (TKL) protein	0.0486	0.3266	1
Brugia malayi	Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit	0.0088	0.0195	0.0338
Schistosoma mansoni	protein phosphatase 2C	0.0095	0.0251	0.0769
Loa Loa (eye worm)	hypothetical protein	0.0088	0.0195	0.0368
Schistosoma mansoni	src-type protein tyrosine kinase-related	0.0486	0.3266	1
Echinococcus multilocularis	tyrosine protein kinase csk	0.0486	0.3266	0.3266
Trichomonas vaginalis	protein tyrosine kinase, putative	0.0486	0.3266	1
Loa Loa (eye worm)	voltage-gated potassium channel	0.0088	0.0195	0.0368
Loa Loa (eye worm)	TKL/RAF/RAF protein kinase	0.0486	0.3266	1
Brugia malayi	SH2 domain containing protein	0.0486	0.3266	1
Brugia malayi	jmjC domain containing protein	0.0136	0.0565	0.1504
Echinococcus granulosus	ephrin type A receptor 4 A	0.0486	0.3266	0.3266
Echinococcus granulosus	c src tyrosine kinase	0.0486	0.3266	0.3266
Loa Loa (eye worm)	hypothetical protein	0.0486	0.3266	1
Brugia malayi	Protein kinase domain containing protein	0.0486	0.3266	1
Echinococcus multilocularis	tyrosine protein kinase csk	0.0486	0.3266	0.3266
Echinococcus multilocularis	potassium voltage gated channel protein	0.0088	0.0195	0.0195
Echinococcus multilocularis	tyrosine kinase	0.0486	0.3266	0.3266
Schistosoma mansoni	serine/threonine RGC	0.0486	0.3266	1
Loa Loa (eye worm)	TK protein kinase	0.0486	0.3266	1
Schistosoma mansoni	60S ribosomal protein L21	0.0088	0.0195	0.0596
Echinococcus multilocularis	ephrin type A receptor 4 A	0.0486	0.3266	0.3266
Entamoeba histolytica	hypothetical protein	0.0541	0.3694	1
Schistosoma mansoni	voltage-gated ion channel	0.0088	0.0195	0.0596
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0486	0.3266	1
Entamoeba histolytica	leucine-rich repeat domain-containing protein	0.0541	0.3694	1
Echinococcus granulosus	lysine specific demethylase 5A	0.0265	0.1563	0.1563
Trypanosoma cruzi	JmjC domain, hydroxylase, putative	0.0095	0.0251	0.0185
Giardia lamblia	Kinase, NEK	0.0486	0.3266	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0486	0.3266	1
Trichomonas vaginalis	TKL family protein kinase	0.0486	0.3266	1
Schistosoma mansoni	serine/threonine protein kinase	0.0486	0.3266	1
Trypanosoma brucei	Flagellum attachment zone protein 20	0.0486	0.3266	1
Echinococcus granulosus	3'partial\|tyrosine protein kinase Fgr	0.0486	0.3266	0.3266
Schistosoma mansoni	voltage-gated potassium channel	0.0088	0.0195	0.0596
Brugia malayi	Cyclic-nucleotide gated cation channel	0.0088	0.0195	0.0338
Schistosoma mansoni	voltage-gated potassium channel KCNQ	0.0088	0.0195	0.0596
Trichomonas vaginalis	TKL family protein kinase	0.0486	0.3266	1
Schistosoma mansoni	tyrosine kinase	0.0486	0.3266	1
Echinococcus multilocularis	potassium:sodium hyperpolarization activated	0.0088	0.0195	0.0195
Brugia malayi	cation channel family protein	0.0088	0.0195	0.0338
Echinococcus granulosus	melanoma receptor tyrosine protein kinase	0.0486	0.3266	0.3266
Echinococcus multilocularis	lysine specific demethylase 5A	0.0263	0.1548	0.1548
Trichomonas vaginalis	TKL family protein kinase	0.0486	0.3266	1
Toxoplasma gondii	protein kinase domain-containing protein	0.0486	0.3266	1
Trichomonas vaginalis	TKL family protein kinase	0.0486	0.3266	1
Trichomonas vaginalis	TKL family protein kinase	0.0486	0.3266	1
Echinococcus granulosus	short transient receptor potential channel 6	0.0088	0.0195	0.0195
Loa Loa (eye worm)	hypothetical protein	0.0088	0.0195	0.0368
Echinococcus multilocularis	tyrosine protein kinase csk	0.0486	0.3266	0.3266
Trichomonas vaginalis	TKL family protein kinase	0.0486	0.3266	1
Brugia malayi	Tyrosine-protein kinase F09A5.2 in chromosome X, putative	0.0486	0.3266	1
Trichomonas vaginalis	TKL family protein kinase	0.0486	0.3266	1
Echinococcus granulosus	hypothetical protein	0.0088	0.0195	0.0195
Plasmodium falciparum	tyrosine kinase-like protein	0.0486	0.3266	1
Echinococcus granulosus	natriuretic peptide receptor 1	0.0486	0.3266	0.3266
Brugia malayi	Protein kinase domain containing protein	0.0486	0.3266	1
Echinococcus multilocularis	potassium voltage gated channel subfamily D	0.0088	0.0195	0.0195
Schistosoma mansoni	tyrosine kinase	0.0486	0.3266	1
Schistosoma mansoni	tyrosine kinase	0.0486	0.3266	1
Schistosoma mansoni	hypothetical protein	0.0088	0.0195	0.0596
Plasmodium falciparum	protein kinase, putative	0.0486	0.3266	1
Schistosoma mansoni	high voltage-activated calcium channel Cav1	0.0088	0.0195	0.0596
Brugia malayi	Protein kinase domain containing protein	0.0486	0.3266	1
Schistosoma mansoni	protein kinase	0.0486	0.3266	1
Schistosoma mansoni	transient receptor potential channel 4	0.0088	0.0195	0.0596
Echinococcus granulosus	macrophage colony stimulating factor 1 receptor	0.0486	0.3266	0.3266
Trypanosoma cruzi	protein kinase, putative	0.0486	0.3266	1
Loa Loa (eye worm)	TK protein kinase	0.0486	0.3266	1
Schistosoma mansoni	tyrosine kinase	0.0486	0.3266	1
Echinococcus granulosus	JmjC domain containing protein 4	0.0095	0.0251	0.0251
Echinococcus multilocularis	transient receptor potential cation channel	0.0088	0.0195	0.0195
Echinococcus multilocularis	cyclic nucleotide gated cation channel	0.0088	0.0195	0.0195
Trypanosoma cruzi	JmjC domain, hydroxylase, putative	0.0095	0.0251	0.0185
Brugia malayi	ion channel NompC	0.0088	0.0195	0.0338
Echinococcus granulosus	tyrosine protein kinase transmembrane receptor	0.0486	0.3266	0.3266
Echinococcus granulosus	fibroblast growth factor receptor 4	0.0486	0.3266	0.3266
Echinococcus multilocularis	conserved hypothetical protein	0.0088	0.0195	0.0195
Trichomonas vaginalis	TKL family protein kinase	0.0486	0.3266	1
Loa Loa (eye worm)	SRC-1	0.0486	0.3266	1
Schistosoma mansoni	voltage-gated cation channel	0.0088	0.0195	0.0596
Trichomonas vaginalis	TKL family protein kinase	0.0486	0.3266	1
Leishmania major	calcium channel protein, putative,ion transporter, putative	0.1359	1	1
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0486	0.3266	0.3266
Loa Loa (eye worm)	TK/ACK protein kinase	0.0486	0.3266	1
Brugia malayi	Protein kinase domain containing protein	0.0486	0.3266	1
Loa Loa (eye worm)	TK/KIN16 protein kinase	0.0486	0.3266	1
Trichomonas vaginalis	TKL family protein kinase	0.0486	0.3266	1
Trichomonas vaginalis	TKL family protein kinase	0.0486	0.3266	1
Toxoplasma gondii	protein kinase	0.0486	0.3266	1
Trichomonas vaginalis	TK family protein kinase	0.0486	0.3266	1
Schistosoma mansoni	protein kinase	0.0486	0.3266	1
Schistosoma mansoni	tyrosine kinase	0.0486	0.3266	1
Trichomonas vaginalis	serine-threonine protein kinase, putative	0.0486	0.3266	1
Schistosoma mansoni	cyclic-nucleotide-gated cation channel	0.0088	0.0195	0.0596
Echinococcus multilocularis	potassium voltage gated channel subfamily C	0.0088	0.0195	0.0195
Echinococcus granulosus	voltage dependent calcium channel	0.0088	0.0195	0.0195
Echinococcus multilocularis	protein kinase	0.0486	0.3266	0.3266
Toxoplasma gondii	histone lysine demethylase JMJC1/KDM5D/JARID1D	0.0126	0.0488	0.0954
Schistosoma mansoni	serine/threonine protein kinase	0.0486	0.3266	1
Loa Loa (eye worm)	hypothetical protein	0.0169	0.0822	0.2335
Echinococcus granulosus	tyrosine protein kinase shark	0.0486	0.3266	0.3266
Echinococcus granulosus	lysine specific demethylase 6a	0.0136	0.0565	0.0565
Echinococcus multilocularis	tyrosine protein kinase HCK	0.0486	0.3266	0.3266
Echinococcus granulosus	tyrosine kinase	0.0486	0.3266	0.3266
Echinococcus granulosus	phd:f box containing protein	0.0095	0.0251	0.0251
Brugia malayi	Protein kinase domain containing protein	0.0486	0.3266	1
Schistosoma mansoni	transient receptor potential cation channel subfamily m member	0.0088	0.0195	0.0596
Loa Loa (eye worm)	ryanodine receptor	0.0088	0.0195	0.0368
Echinococcus multilocularis	tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase	0.0486	0.3266	0.3266
Onchocerca volvulus		0.0486	0.3266	1
Trichomonas vaginalis	TKL family protein kinase	0.0486	0.3266	1
Brugia malayi	Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog	0.0088	0.0195	0.0338
Schistosoma mansoni	tyrosine kinase	0.0486	0.3266	1
Onchocerca volvulus		0.0486	0.3266	1
Schistosoma mansoni	tyrosine kinase	0.0486	0.3266	1
Schistosoma mansoni	vesicular amine transporter	0.0088	0.0195	0.0596
Schistosoma mansoni	voltage-gated potassium channel	0.0088	0.0195	0.0596
Echinococcus multilocularis	potassium voltage gated channel subfamily H	0.0088	0.0195	0.0195
Echinococcus multilocularis	potassium voltage gated channel protein	0.0088	0.0195	0.0195
Brugia malayi	Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog	0.0088	0.0195	0.0338
Echinococcus granulosus	tyrosine protein kinase HCK	0.0486	0.3266	0.3266
Loa Loa (eye worm)	TK protein kinase	0.0486	0.3266	1
Brugia malayi	Protein kinase domain containing protein	0.0486	0.3266	1
Entamoeba histolytica	hypothetical protein	0.0541	0.3694	1
Echinococcus granulosus	potassium voltage gated channel subfamily D	0.0088	0.0195	0.0195
Brugia malayi	Protein kinase domain containing protein	0.0486	0.3266	1
Schistosoma mansoni	tyrosine kinase	0.0486	0.3266	1
Echinococcus granulosus	potassium large conductance calcium activated	0.0088	0.0195	0.0195
Echinococcus granulosus	retinal guanylyl cyclase 2	0.0486	0.3266	0.3266
Echinococcus granulosus	voltage dependent calcium channel type d subunit\|voltage dependent calcium channel\|voltage dependent L type calcium channel subu	0.0088	0.0195	0.0195
Schistosoma mansoni	protein kinase	0.0486	0.3266	1
Schistosoma mansoni	cyclic-nucleotide-gated cation channel	0.0088	0.0195	0.0596
Trichomonas vaginalis	TKL family protein kinase	0.0486	0.3266	1
Brugia malayi	Protein kinase domain containing protein	0.0486	0.3266	1
Echinococcus multilocularis	tyrosine protein kinase	0.0486	0.3266	0.3266
Loa Loa (eye worm)	hypothetical protein	0.0486	0.3266	1
Trichomonas vaginalis	conserved hypothetical protein	0.0486	0.3266	1
Trichomonas vaginalis	TKL family protein kinase	0.0486	0.3266	1
Schistosoma mansoni	voltage-gated potassium channel	0.0088	0.0195	0.0596
Schistosoma mansoni	cyclic-nucleotide-gated cation channel	0.0088	0.0195	0.0596
Loa Loa (eye worm)	hypothetical protein	0.0088	0.0195	0.0368
Echinococcus multilocularis	voltage gated potassium channel	0.0088	0.0195	0.0195
Brugia malayi	Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit	0.0088	0.0195	0.0338
Echinococcus multilocularis	macrophage colony stimulating factor 1 receptor	0.0486	0.3266	0.3266
Trichomonas vaginalis	TKL family protein kinase	0.0486	0.3266	1
Echinococcus granulosus	insulin growth factor 1 receptor beta	0.0486	0.3266	0.3266
Echinococcus granulosus	potassium voltage gated channel subfamily H	0.0088	0.0195	0.0195
Trichomonas vaginalis	TKL family protein kinase	0.0486	0.3266	1
Schistosoma mansoni	transient receptor potential cation channel subfamily m member	0.0088	0.0195	0.0596
Schistosoma mansoni	tyrosine kinase	0.0486	0.3266	1
Loa Loa (eye worm)	TK/FER protein kinase	0.0486	0.3266	1
Echinococcus granulosus	voltage dependent calcium channel	0.0088	0.0195	0.0195
Schistosoma mansoni	phosphatidylserine receptor	0.0095	0.0251	0.0769
Toxoplasma gondii	histone lysine demethylase JMJD6a	0.0095	0.0251	0.0185
Echinococcus granulosus	potassium voltage gated channel protein	0.0088	0.0195	0.0195
Brugia malayi	hypothetical protein	0.0088	0.0195	0.0338
Onchocerca volvulus		0.0486	0.3266	1
Echinococcus granulosus	short transient receptor potential channel 6	0.0088	0.0195	0.0195
Loa Loa (eye worm)	serine/threonine protein kinase	0.0486	0.3266	1
Schistosoma mansoni	transient receptor potential cation channel subfamily m member	0.0088	0.0195	0.0596
Loa Loa (eye worm)	TK/FER protein kinase	0.0486	0.3266	1
Loa Loa (eye worm)	TK/FER protein kinase	0.0486	0.3266	1
Schistosoma mansoni	tyrosine kinase	0.0486	0.3266	1
Echinococcus granulosus	retinal guanylyl cyclase 2	0.0486	0.3266	0.3266
Echinococcus multilocularis	mitogen activated protein kinase kinase kinase	0.0486	0.3266	0.3266
Trichomonas vaginalis	TKL family protein kinase	0.0486	0.3266	1
Brugia malayi	jmjC domain containing protein	0.0095	0.0251	0.0516
Trypanosoma brucei	protein kinase, putative	0.0486	0.3266	1
Echinococcus granulosus	protein kinase	0.0486	0.3266	0.3266
Onchocerca volvulus		0.0486	0.3266	1
Echinococcus multilocularis	proto oncogene tyrosine protein kinase LCK	0.0486	0.3266	0.3266
Trichomonas vaginalis	TKL family protein kinase	0.0486	0.3266	1
Echinococcus multilocularis	phd:f box containing protein	0.0095	0.0251	0.0251
Loa Loa (eye worm)	TK/ALK protein kinase	0.0486	0.3266	1
Brugia malayi	hypothetical protein	0.0486	0.3266	1
Brugia malayi	Protein kinase domain containing protein	0.0486	0.3266	1
Echinococcus granulosus	hyperpolarization activated cyclic	0.0088	0.0195	0.0195
Echinococcus multilocularis	potassium large conductance calcium activated	0.0088	0.0195	0.0195
Echinococcus multilocularis	activin receptor type	0.0486	0.3266	0.3266
Echinococcus multilocularis	Transcription factor, JmjC domain containing protein	0.0274	0.1628	0.1628
Echinococcus granulosus	tyrosine protein kinase pr2	0.0486	0.3266	0.3266
Onchocerca volvulus	Atrial natriuretic peptide receptor 3 homolog	0.0486	0.3266	1
Echinococcus multilocularis	transient receptor potential cation channel	0.0088	0.0195	0.0195
Schistosoma mansoni	inositol 145-trisphosphate receptor	0.0088	0.0195	0.0596
Trichomonas vaginalis	conserved hypothetical protein	0.0486	0.3266	1
Echinococcus multilocularis	transient receptor potential cation channel	0.0088	0.0195	0.0195
Echinococcus multilocularis	jumonji domain containing 1A	0.0188	0.0965	0.0965
Brugia malayi	proto-oncogene tyrosine-protein kinase FER	0.0486	0.3266	1
Brugia malayi	Protein kinase domain containing protein	0.0486	0.3266	1
Schistosoma mansoni	ephrin receptor	0.0486	0.3266	1
Onchocerca volvulus	Tyrosine kinase homolog	0.0486	0.3266	1
Onchocerca volvulus		0.0486	0.3266	1
Schistosoma mansoni	voltage-gated potassium channel	0.0088	0.0195	0.0596
Schistosoma mansoni	voltage-gated potassium channel	0.0088	0.0195	0.0596
Schistosoma mansoni	protein kinase	0.0486	0.3266	1
Loa Loa (eye worm)	hypothetical protein	0.0088	0.0195	0.0368
Schistosoma mansoni	tyrosine protein kinase	0.0486	0.3266	1
Loa Loa (eye worm)	TK/FER protein kinase	0.0486	0.3266	1
Schistosoma mansoni	cyclic-nucleotide-gated cation channel	0.0088	0.0195	0.0596
Echinococcus multilocularis	short transient receptor potential channel 6	0.0088	0.0195	0.0195
Trichomonas vaginalis	TKL family protein kinase	0.0486	0.3266	1
Loa Loa (eye worm)	TK/RYK protein kinase	0.0486	0.3266	1
Echinococcus multilocularis	basic fibroblast growth factor receptor 1 A	0.0486	0.3266	0.3266
Loa Loa (eye worm)	hypothetical protein	0.0088	0.0195	0.0368
Trichomonas vaginalis	TKL family protein kinase	0.0486	0.3266	1
Echinococcus multilocularis	tyrosine protein kinase shark	0.0486	0.3266	0.3266
Schistosoma mansoni	tyrosine kinase	0.0486	0.3266	1
Echinococcus multilocularis	potassium voltage gated channel protein	0.0088	0.0195	0.0195
Giardia lamblia	Protein 21.1	0.0486	0.3266	0.5
Loa Loa (eye worm)	TK protein kinase	0.0486	0.3266	1
Echinococcus multilocularis	voltage dependent calcium channel	0.0088	0.0195	0.0195
Trichomonas vaginalis	TKL family protein kinase	0.0486	0.3266	1
Brugia malayi	Transient-receptor-potential like protein	0.0088	0.0195	0.0338
Echinococcus multilocularis	tyrosine protein kinase csk	0.0486	0.3266	0.3266
Schistosoma mansoni	transient receptor potential cation channel subfamily m member	0.0088	0.0195	0.0596
Echinococcus multilocularis	tyrosine protein kinase Blk	0.0486	0.3266	0.3266
Echinococcus granulosus	tyrosine protein kinase Btk29A	0.0486	0.3266	0.3266
Echinococcus granulosus	shaker cognate	0.0088	0.0195	0.0195
Echinococcus multilocularis	protein kinase	0.0486	0.3266	0.3266
Giardia lamblia	Kinase	0.0486	0.3266	0.5
Loa Loa (eye worm)	ion channel NompC	0.0088	0.0195	0.0368
Echinococcus multilocularis	tyrosine protein kinase Btk29A	0.0486	0.3266	0.3266
Schistosoma mansoni	protein kinase	0.0486	0.3266	1
Loa Loa (eye worm)	voltage-gated potassium channel	0.0088	0.0195	0.0368
Echinococcus granulosus	tyrosine kinase	0.0486	0.3266	0.3266
Plasmodium vivax	tyrosine kinase-like protein, putative	0.0486	0.3266	1
Schistosoma mansoni	transient receptor potential channel	0.0088	0.0195	0.0596
Echinococcus multilocularis	calcium activated potassium channel	0.0088	0.0195	0.0195
Brugia malayi	cation channel family protein	0.0088	0.0195	0.0338
Brugia malayi	Protein kinase domain containing protein	0.0486	0.3266	1
Brugia malayi	Protein kinase domain containing protein	0.0486	0.3266	1
Trichomonas vaginalis	conserved hypothetical protein	0.0486	0.3266	1
Echinococcus multilocularis	hyperpolarization activated cyclic	0.0088	0.0195	0.0195
Trichomonas vaginalis	TKL family protein kinase	0.0486	0.3266	1
Plasmodium falciparum	protein kinase, putative	0.0486	0.3266	1
Echinococcus multilocularis	potassium voltage gated channel subfamily A	0.0088	0.0195	0.0195
Echinococcus granulosus	voltage dependent calcium channel type d subunit\|voltage dependent calcium channel alpha 1	0.0088	0.0195	0.0195
Echinococcus granulosus	atrial natriuretic peptide receptor 1	0.0486	0.3266	0.3266
Schistosoma mansoni	jumonji/arid domain-containing protein	0.0265	0.1563	0.4786
Brugia malayi	Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog	0.0088	0.0195	0.0338
Loa Loa (eye worm)	hypothetical protein	0.0486	0.3266	1
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0486	0.3266	0.3266
Schistosoma mansoni	protein kinase	0.0486	0.3266	1
Loa Loa (eye worm)	voltage and ligand gated potassium channel	0.0088	0.0195	0.0368
Schistosoma mansoni	voltage-gated potassium channel	0.0088	0.0195	0.0596
Schistosoma mansoni	proto-oncogene tyrosine-protein kinase src	0.0486	0.3266	1
Trichomonas vaginalis	TKL family protein kinase	0.0486	0.3266	1
Loa Loa (eye worm)	TK protein kinase	0.0486	0.3266	1
Brugia malayi	voltage-dependent calcium channel	0.0088	0.0195	0.0338
Onchocerca volvulus		0.0486	0.3266	1
Trypanosoma cruzi	STE/STE11 serine/threonine-protein kinase, putative	0.0486	0.3266	1
Trichomonas vaginalis	TKL family protein kinase	0.0486	0.3266	1
Schistosoma mansoni	tyrosine kinase	0.0486	0.3266	1
Loa Loa (eye worm)	jmjC domain-containing protein	0.0095	0.0251	0.0546
Echinococcus multilocularis	tyrosine protein kinase Srms	0.0486	0.3266	0.3266
Echinococcus multilocularis	atrial natriuretic peptide receptor 1	0.0486	0.3266	0.3266
Schistosoma mansoni	transient receptor potential cation channel subfamily m member	0.0088	0.0195	0.0596
Brugia malayi	Protein kinase domain containing protein	0.0486	0.3266	1
Brugia malayi	Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog	0.0088	0.0195	0.0338
Schistosoma mansoni	protein kinase	0.0486	0.3266	1
Onchocerca volvulus		0.0486	0.3266	1
Echinococcus granulosus	tyrosine protein kinase transmembrane receptor	0.0486	0.3266	0.3266
Loa Loa (eye worm)	hypothetical protein	0.0486	0.3266	1
Echinococcus granulosus	protein tyrosine kinase	0.0486	0.3266	0.3266
Echinococcus granulosus	potassium voltage gated channel protein	0.0088	0.0195	0.0195
Echinococcus granulosus	tyrosine protein kinase Fes:Fps	0.0486	0.3266	0.3266
Brugia malayi	Protein kinase domain containing protein	0.0486	0.3266	1
Loa Loa (eye worm)	hypothetical protein	0.0088	0.0195	0.0368
Brugia malayi	C-terminal src kinase protein 1	0.0486	0.3266	1
Brugia malayi	Adenylate and Guanylate cyclase catalytic domain containing protein	0.0486	0.3266	1
Schistosoma mansoni	tyrosine kinase	0.0486	0.3266	1
Loa Loa (eye worm)	hypothetical protein	0.0088	0.0195	0.0368
Brugia malayi	Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit	0.0088	0.0195	0.0338
Plasmodium falciparum	protein kinase, putative	0.0486	0.3266	1
Schistosoma mansoni	voltage-gated potassium channel	0.0088	0.0195	0.0596
Echinococcus granulosus	two pore calcium channel protein 1	0.0088	0.0195	0.0195
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.0486	0.3266	0.3266
Brugia malayi	jmjC domain containing protein	0.0318	0.1969	0.592
Schistosoma mansoni	tyrosine kinase	0.0486	0.3266	1
Echinococcus multilocularis	tyrosine protein kinase transmembrane receptor	0.0486	0.3266	0.3266
Schistosoma mansoni	calcium-activated potassium channel	0.0088	0.0195	0.0596
Trichomonas vaginalis	TKL family protein kinase	0.0486	0.3266	1
Echinococcus multilocularis	FL cytokine receptor	0.0486	0.3266	0.3266
Echinococcus granulosus	tyrosine protein kinase csk	0.0486	0.3266	0.3266
Loa Loa (eye worm)	hypothetical protein	0.0088	0.0195	0.0368
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0486	0.3266	0.3266
Schistosoma mansoni	protein kinase	0.0486	0.3266	1
Schistosoma mansoni	tyrosine kinase	0.0486	0.3266	1
Echinococcus granulosus	tyrosine protein kinase Src42A	0.0486	0.3266	0.3266
Echinococcus granulosus	mitogen-activated protein kinase kinase kinase 9	0.0486	0.3266	0.3266
Trichomonas vaginalis	TKL family protein kinase	0.0486	0.3266	1
Schistosoma mansoni	high voltage-activated calcium channel Cav2A	0.0088	0.0195	0.0596
Echinococcus granulosus	proto oncogene tyrosine protein kinase LCK	0.0486	0.3266	0.3266
Loa Loa (eye worm)	TK/FER protein kinase	0.0486	0.3266	1
Trichomonas vaginalis	conserved hypothetical protein	0.0486	0.3266	1
Echinococcus granulosus	integrin linked protein kinase	0.0486	0.3266	0.3266
Loa Loa (eye worm)	hypothetical protein	0.0088	0.0195	0.0368
Brugia malayi	Voltage-gated calcium channel, alpha subunit	0.0088	0.0195	0.0338
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0486	0.3266	1
Loa Loa (eye worm)	jmjC domain-containing protein	0.0095	0.0251	0.0546
Loa Loa (eye worm)	TK/FER protein kinase	0.0486	0.3266	1
Trichomonas vaginalis	TKL family protein kinase	0.0486	0.3266	1
Trichomonas vaginalis	TKL family protein kinase	0.0486	0.3266	1
Echinococcus granulosus	activin receptor type	0.0486	0.3266	0.3266
Loa Loa (eye worm)	TK/FER protein kinase	0.0486	0.3266	1
Echinococcus granulosus	potassium voltage gated channel protein	0.0088	0.0195	0.0195
Loa Loa (eye worm)	hypothetical protein	0.0136	0.0565	0.153
Schistosoma mansoni	tyrosine kinase	0.0486	0.3266	1
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0486	0.3266	1
Schistosoma mansoni	protein kinase	0.0486	0.3266	1
Brugia malayi	Probable tyrosine-protein kinase kin-31	0.0486	0.3266	1
Brugia malayi	jmjC domain containing protein	0.0095	0.0251	0.0516
Echinococcus granulosus	tyrosine kinase	0.0486	0.3266	0.3266
Brugia malayi	ephrin receptor 1 precursor	0.0486	0.3266	1
Toxoplasma gondii	Tyrosine kinase-like (TKL) protein	0.0486	0.3266	1
Loa Loa (eye worm)	hypothetical protein	0.0486	0.3266	1
Brugia malayi	Protein kinase domain containing protein	0.0486	0.3266	1
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0486	0.3266	1
Schistosoma mansoni	hyperpolarization activated cyclic nucleotide-gated potassium channel	0.0088	0.0195	0.0596
Brugia malayi	Protein kinase domain containing protein	0.0486	0.3266	1
Echinococcus multilocularis	shaker cognate	0.0088	0.0195	0.0195
Loa Loa (eye worm)	TK/INSR protein kinase	0.0486	0.3266	1
Echinococcus multilocularis	heat shock protein 70	0.0486	0.3266	0.3266
Echinococcus multilocularis	insulin receptor	0.0486	0.3266	0.3266
Schistosoma mansoni	tyrosine kinase	0.0486	0.3266	1
Schistosoma mansoni	tyrosine-protein kinase fps85d	0.0486	0.3266	1
Onchocerca volvulus		0.0486	0.3266	1
Loa Loa (eye worm)	hypothetical protein	0.0144	0.0629	0.1731
Brugia malayi	Protein kinase domain containing protein	0.0486	0.3266	1
Echinococcus granulosus	Transcription factor JmjC domain containing protein	0.0274	0.1628	0.1628
Loa Loa (eye worm)	TK protein kinase	0.0486	0.3266	1
Loa Loa (eye worm)	hypothetical protein	0.0088	0.0195	0.0368
Schistosoma mansoni	tyrosine kinase	0.0486	0.3266	1
Echinococcus multilocularis	JmjC domain containing protein 4	0.0095	0.0251	0.0251
Schistosoma mansoni	hypothetical protein	0.0486	0.3266	1
Loa Loa (eye worm)	TK/ABL protein kinase	0.0486	0.3266	1
Echinococcus granulosus	insulin receptor	0.0486	0.3266	0.3266
Loa Loa (eye worm)	TK/FER protein kinase	0.0486	0.3266	1
Echinococcus multilocularis	short transient receptor potential channel 6	0.0088	0.0195	0.0195
Echinococcus multilocularis	mitogen activated protein kinase kinase kinase	0.0486	0.3266	0.3266
Echinococcus multilocularis	potassium voltage gated channel subfamily KQT	0.0088	0.0195	0.0195
Echinococcus granulosus	receptor type guanylyl cyclase	0.0486	0.3266	0.3266
Schistosoma mansoni	jumonji domain containing protein	0.025	0.1445	0.4423
Trichomonas vaginalis	TKL family protein kinase	0.0486	0.3266	1
Trichomonas vaginalis	TKL family protein kinase	0.0486	0.3266	1
Brugia malayi	jmjC domain containing protein	0.0274	0.1628	0.4845
Schistosoma mansoni	voltage-gated potassium channel	0.0088	0.0195	0.0596
Loa Loa (eye worm)	TK/FER protein kinase	0.0486	0.3266	1
Loa Loa (eye worm)	TK/ROR protein kinase	0.0486	0.3266	1
Trichomonas vaginalis	TKL family protein kinase	0.0486	0.3266	1
Echinococcus granulosus	jumonji domain containing 1A	0.0188	0.0965	0.0965
Loa Loa (eye worm)	hypothetical protein	0.0088	0.0195	0.0368
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0486	0.3266	0.3266
Trichomonas vaginalis	TKL family protein kinase	0.0486	0.3266	1
Loa Loa (eye worm)	jmjC domain-containing protein	0.0188	0.0965	0.2782
Schistosoma mansoni	tyrosine kinase	0.0486	0.3266	1
Echinococcus multilocularis	tyrosine kinase	0.0486	0.3266	0.3266
Echinococcus multilocularis	voltage dependent calcium channel	0.0088	0.0195	0.0195
Echinococcus multilocularis	integrin linked protein kinase	0.0486	0.3266	0.3266
Loa Loa (eye worm)	TK/EPH protein kinase	0.0486	0.3266	1
Loa Loa (eye worm)	TK/FER protein kinase	0.0486	0.3266	1
Echinococcus multilocularis	epidermal growth factor receptor	0.0486	0.3266	0.3266
Schistosoma mansoni	voltage-gated potassium channel	0.0088	0.0195	0.0596
Loa Loa (eye worm)	jmjC domain-containing protein	0.0318	0.1969	0.5933
Loa Loa (eye worm)	TK/FER protein kinase	0.0486	0.3266	1
Trypanosoma brucei	STE/STE11 serine/threonine-protein kinase, putative	0.0486	0.3266	1
Loa Loa (eye worm)	hypothetical protein	0.0088	0.0195	0.0368
Trichomonas vaginalis	TKL family protein kinase	0.0486	0.3266	1
Echinococcus granulosus	voltage dependent L type calcium channel subunit\|voltage dependent calcium channel	0.0088	0.0195	0.0195
Loa Loa (eye worm)	TK/FER protein kinase	0.0486	0.3266	1
Loa Loa (eye worm)	TKL/RAF/KSR protein kinase	0.0486	0.3266	1
Schistosoma mansoni	voltage-gated potassium channel	0.0088	0.0195	0.0596
Brugia malayi	Probable tyrosine-protein kinase kin-31	0.0486	0.3266	1
Brugia malayi	integrin-linked kinase	0.0486	0.3266	1
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0486	0.3266	1
Trypanosoma cruzi	protein kinase, putative	0.0486	0.3266	1
Schistosoma mansoni	tyrosine kinase	0.0486	0.3266	1
Echinococcus granulosus	TRP transient receptor potential channel	0.0088	0.0195	0.0195
Echinococcus granulosus	potassium:sodium hyperpolarization activated	0.0088	0.0195	0.0195
Schistosoma mansoni	tyrosine kinase	0.0486	0.3266	1
Schistosoma mansoni	tyrosine kinase	0.0486	0.3266	1
Schistosoma mansoni	voltage-gated potassium channel	0.0088	0.0195	0.0596
Trichomonas vaginalis	TKL family protein kinase	0.0486	0.3266	1
Brugia malayi	Adenylate and Guanylate cyclase catalytic domain containing protein	0.0486	0.3266	1
Trichomonas vaginalis	TKL family protein kinase	0.0486	0.3266	1
Schistosoma mansoni	tyrosine protein kinase fes (fps) (ptk group IV)	0.0486	0.3266	1
Echinococcus granulosus	Jumonji AT rich interactive domain 1B	0.0207	0.1115	0.1115
Brugia malayi	Ryanodine Receptor TM 4-6 family protein	0.0088	0.0195	0.0338
Echinococcus multilocularis	tyrosine protein kinase ABL1	0.0486	0.3266	0.3266
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.0486	0.3266	0.3266
Echinococcus multilocularis	voltage dependent L type calcium channel subunit	0.0088	0.0195	0.0195
Echinococcus multilocularis	two pore calcium channel protein 1	0.0088	0.0195	0.0195
Loa Loa (eye worm)	hypothetical protein	0.0088	0.0195	0.0368
Echinococcus granulosus	tyrosine protein kinase Lyn	0.0486	0.3266	0.3266
Schistosoma mansoni	hyperpolarization activated cyclic nucleotide-gated potassium channel	0.0088	0.0195	0.0596
Echinococcus multilocularis	protein KINase family member (kin 25)	0.0486	0.3266	0.3266
Schistosoma mansoni	ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related	0.0136	0.0565	0.173
Echinococcus multilocularis	tyrosine protein kinase Abl	0.0486	0.3266	0.3266
Echinococcus multilocularis	natriuretic peptide receptor 1	0.0486	0.3266	0.3266
Schistosoma mansoni	voltage-dependent calcium channel	0.0088	0.0195	0.0596
Loa Loa (eye worm)	hypothetical protein	0.0486	0.3266	1
Loa Loa (eye worm)	hypothetical protein	0.0088	0.0195	0.0368
Trichomonas vaginalis	TKL family protein kinase	0.0486	0.3266	1
Schistosoma mansoni	voltage-gated potassium channel	0.0088	0.0195	0.0596
Trichomonas vaginalis	conserved hypothetical protein	0.0486	0.3266	1
Brugia malayi	Protein kinase domain containing protein	0.0486	0.3266	1
Schistosoma mansoni	ryanodine receptor related	0.0088	0.0195	0.0596
Echinococcus multilocularis	transfer RNA-Gly	0.0088	0.0195	0.0195
Schistosoma mansoni	tyrosine kinase	0.0486	0.3266	1
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.0486	0.3266	0.3266
Onchocerca volvulus	Tyrosine kinase receptor Cad96Ca homolog	0.0486	0.3266	1
Echinococcus multilocularis	c src tyrosine kinase	0.0486	0.3266	0.3266
Brugia malayi	Protein kinase domain containing protein	0.0486	0.3266	1
Echinococcus multilocularis	hyperpolarization activated cyclic	0.0088	0.0195	0.0195
Schistosoma mansoni	tyrosine kinase	0.0486	0.3266	1
Brugia malayi	Protein kinase domain containing protein	0.0486	0.3266	1

Activities

Activity type	Activity value	Assay description	Source	Reference
IC50 (binding)	= 0.03 uM	Inhibition of recombinant JARID1C (unknown origin) incubated for 15 mins prior to substrate addition by AlphaScreen method	ChEMBL.	24325601
IC50 (binding)	= 1.1 uM	Inhibition of recombinant JMJD1A (unknown origin) incubated for 15 mins prior to substrate addition by AlphaScreen method	ChEMBL.	24325601
IC50 (binding)	= 3.5 uM	Inhibition of recombinant JMJD2C (unknown origin) incubated for 15 mins prior to substrate addition by AlphaScreen method	ChEMBL.	24325601
IC50 (binding)	= 4.8 uM	Inhibition of recombinant FBXL11 (unknown origin) incubated for 15 mins prior to substrate addition by AlphaScreen method	ChEMBL.	24325601
IC50 (binding)	= 5 uM	Inhibition of recombinant JMJD2E (unknown origin) incubated for 15 mins prior to substrate addition by AlphaScreen method	ChEMBL.	24325601
IC50 (binding)	= 11.2 uM	Inhibition of recombinant JMJD3 (unknown origin) incubated for 15 mins prior to substrate addition by AlphaScreen method	ChEMBL.	24325601
IC50 (binding)	> 100 uM	Inhibition of human recombinant His-tagged LSD1 (171 to 836) assessed as hydrogen peroxide formation after 5 mins	ChEMBL.	24325601

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL3108956

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 1828422