Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.1804 | 0.896 | 1 |
Giardia lamblia | Kinase, CMGC MAPK | 0.1804 | 0.896 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.1804 | 0.896 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.1804 | 0.896 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.1804 | 0.896 | 1 |
Echinococcus granulosus | mitogen activated protein kinase | 0.1804 | 0.896 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.1804 | 0.896 | 1 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.1804 | 0.896 | 0.5 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.1804 | 0.896 | 1 |
Echinococcus multilocularis | cyclin dependent kinase 9 | 0.108 | 0.4892 | 0.546 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.1804 | 0.896 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.1804 | 0.896 | 1 |
Plasmodium falciparum | MO15-related protein kinase | 0.0209 | 0 | 0.5 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.1804 | 0.896 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.108 | 0.4892 | 0.546 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.1804 | 0.896 | 1 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.1804 | 0.896 | 1 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.1804 | 0.896 | 1 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.1804 | 0.896 | 1 |
Brugia malayi | cyclin-dependent kinase 9 | 0.108 | 0.4892 | 0.546 |
Echinococcus granulosus | cyclin dependent kinase 9 | 0.1265 | 0.5932 | 0.6621 |
Brugia malayi | MAP kinase sur-1 | 0.1804 | 0.896 | 1 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.1804 | 0.896 | 0.896 |
Echinococcus multilocularis | cyclin dependent kinase 9 | 0.1265 | 0.5932 | 0.6621 |
Entamoeba histolytica | protein kinase domain containing protein | 0.108 | 0.4892 | 1 |
Schistosoma mansoni | kinase | 0.108 | 0.4892 | 0.546 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.1804 | 0.896 | 1 |
Echinococcus granulosus | cyclin dependent kinase 9 | 0.108 | 0.4892 | 0.546 |
Loa Loa (eye worm) | CMGC/CDK/CDK9 protein kinase | 0.108 | 0.4892 | 0.546 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.1804 | 0.896 | 1 |
Plasmodium vivax | serine/threonine protein kinase KIN, putative | 0.0209 | 0 | 0.5 |
Plasmodium vivax | cyclin dependent kinase 7 (cdk7), putative | 0.0209 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.