Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | CMGC/CDK/CDK9 protein kinase | 0.108 | 0.4892 | 0.546 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.1804 | 0.896 | 1 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.1804 | 0.896 | 1 |
Schistosoma mansoni | kinase | 0.108 | 0.4892 | 0.546 |
Entamoeba histolytica | protein kinase domain containing protein | 0.108 | 0.4892 | 1 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.1804 | 0.896 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.1804 | 0.896 | 1 |
Brugia malayi | MAP kinase sur-1 | 0.1804 | 0.896 | 1 |
Echinococcus multilocularis | cyclin dependent kinase 9 | 0.108 | 0.4892 | 0.546 |
Echinococcus granulosus | cyclin dependent kinase 9 | 0.1265 | 0.5932 | 0.6621 |
Plasmodium vivax | serine/threonine protein kinase KIN, putative | 0.0209 | 0 | 0.5 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.1804 | 0.896 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.108 | 0.4892 | 0.546 |
Echinococcus granulosus | mitogen activated protein kinase | 0.1804 | 0.896 | 1 |
Brugia malayi | cyclin-dependent kinase 9 | 0.108 | 0.4892 | 0.546 |
Plasmodium vivax | cyclin dependent kinase 7 (cdk7), putative | 0.0209 | 0 | 0.5 |
Echinococcus multilocularis | cyclin dependent kinase 9 | 0.1265 | 0.5932 | 0.6621 |
Trichomonas vaginalis | CMGC family protein kinase | 0.1804 | 0.896 | 1 |
Echinococcus granulosus | cyclin dependent kinase 9 | 0.108 | 0.4892 | 0.546 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.1804 | 0.896 | 1 |
Plasmodium falciparum | MO15-related protein kinase | 0.0209 | 0 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.1804 | 0.896 | 1 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.1804 | 0.896 | 0.896 |
Giardia lamblia | Kinase, CMGC MAPK | 0.1804 | 0.896 | 1 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.1804 | 0.896 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.1804 | 0.896 | 1 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.1804 | 0.896 | 1 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.1804 | 0.896 | 1 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.1804 | 0.896 | 0.5 |
Schistosoma mansoni | serine/threonine protein kinase | 0.1804 | 0.896 | 1 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.1804 | 0.896 | 1 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.1804 | 0.896 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.