Detailed information for compound 1831028

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 229.317 | Formula: C15H19NO
  • H donors: 1 H acceptors: 1 LogP: 2.5 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(=O)c1ccc(cc1)/C=C/[C@@H]1CCCCN1
  • InChi: 1S/C15H19NO/c1-12(17)14-8-5-13(6-9-14)7-10-15-4-2-3-11-16-15/h5-10,15-16H,2-4,11H2,1H3/b10-7+/t15-/m0/s1
  • InChiKey: CLGDEYFJDOYUDZ-VSGCLNPGSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0063 0.0142 0.0343
Schistosoma mansoni neuropeptide receptor 0.0136 0.0562 0.0727
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.1677 0.9404 0.9403
Trichomonas vaginalis WD repeat domain, putative 0.0068 0.0168 0.0404
Loa Loa (eye worm) hypothetical protein 0.1343 0.7487 0.7487
Echinococcus multilocularis rhodopsin orphan GPCR 0.0136 0.0562 0.0544
Trypanosoma cruzi cyclin 6, putative 0.0073 0.0196 0.3282
Echinococcus multilocularis Tubulin beta 2C chain 0.0135 0.0556 0.0538
Echinococcus granulosus somatostatin receptor 0.0136 0.0562 0.0544
Trypanosoma brucei beta tubulin 0.0135 0.0556 1
Loa Loa (eye worm) hypothetical protein 0.02 0.093 0.093
Trichomonas vaginalis cyclin B, putative 0.0073 0.0196 0.0473
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0063 0.0142 0.0343
Brugia malayi Cyclin, N-terminal domain containing protein 0.0073 0.0196 0.0178
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0373 0.192 0.4622
Loa Loa (eye worm) hypothetical protein 0.0136 0.0562 0.0562
Echinococcus multilocularis dnaJ subfamily B 0.04 0.2074 0.2059
Echinococcus granulosus neuropeptide s receptor 0.0136 0.0562 0.0544
Loa Loa (eye worm) hypothetical protein 0.0604 0.3246 0.3246
Echinococcus granulosus biogenic amine 5HT receptor 0.0136 0.0562 0.0544
Onchocerca volvulus 0.0068 0.0168 0.0324
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0136 0.0562 0.0562
Echinococcus granulosus alpha 1A adrenergic receptor 0.0136 0.0562 0.0544
Brugia malayi larval opioid receptor 0.0136 0.0562 0.0544
Trypanosoma brucei beta tubulin 0.0135 0.0556 1
Trichomonas vaginalis conserved hypothetical protein 0.0063 0.0142 0.0343
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.02 0.093 0.1219
Leishmania major beta tubulin 0.0135 0.0556 1
Schistosoma mansoni biogenic amine (5HT) receptor 0.0136 0.0562 0.0727
Trichomonas vaginalis cyclins, putative 0.005 0.0064 0.0155
Loa Loa (eye worm) hypothetical protein 0.0072 0.0193 0.0193
Trichomonas vaginalis tubulin, putative 0.0135 0.0556 0.1338
Leishmania major beta tubulin 0.0135 0.0556 1
Echinococcus granulosus neuroendocrine convertase 2 0.0954 0.5253 0.5244
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0042 0.0021 0.0021
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0063 0.0142 0.0343
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0136 0.0562 0.0562
Brugia malayi Membrane-bound transcription factor site-1 protease precursor 0.0063 0.0142 0.0124
Toxoplasma gondii subtilisin SUB5 0.0063 0.0142 0.2564
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0078 0.0224 0.3822
Onchocerca volvulus 0.0136 0.0562 0.5334
Echinococcus multilocularis cyclin dependent kinase 1 0.0042 0.0021 0.0002
Schistosoma mansoni adenoreceptor 0.0136 0.0562 0.0727
Brugia malayi RE15519p 0.0136 0.0562 0.0544
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0373 0.192 0.4622
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0136 0.0562 0.0562
Trypanosoma cruzi cyclin, putative 0.0073 0.0196 0.3282
Trichomonas vaginalis conserved hypothetical protein 0.0063 0.0142 0.0343
Echinococcus granulosus Tubulin beta 2C chain 0.0135 0.0556 0.0538
Trichomonas vaginalis conserved hypothetical protein 0.0286 0.1423 0.3425
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0373 0.192 0.4622
Schistosoma mansoni hypothetical protein 0.0136 0.0562 0.0727
Loa Loa (eye worm) hypothetical protein 0.0136 0.0562 0.0562
Echinococcus granulosus Tubulin beta 2C chain 0.0135 0.0556 0.0538
Echinococcus multilocularis neuropeptide receptor A26 0.0136 0.0562 0.0544
Loa Loa (eye worm) hypothetical protein 0.0136 0.0562 0.0562
Mycobacterium tuberculosis Probable membrane-anchored mycosin MycP3 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-3) 0.0063 0.0142 0.5
Entamoeba histolytica cyclin, putative 0.0073 0.0196 0.3282
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0136 0.0562 0.0727
Onchocerca volvulus 0.0136 0.0562 0.5334
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0136 0.0562 0.0544
Echinococcus granulosus peptidase s8 s53 subtilisin kexin sedolisin 0.0063 0.0142 0.0124
Echinococcus multilocularis Tubulin beta 2C chain 0.0135 0.0556 0.0538
Brugia malayi hypothetical protein 0.0136 0.0562 0.0544
Echinococcus granulosus tm gpcr rhodopsin 0.0136 0.0562 0.0544
Loa Loa (eye worm) hypothetical protein 0.0136 0.0562 0.0562
Giardia lamblia High cysteine membrane protein Group 2 0.0413 0.2148 1
Loa Loa (eye worm) BEN-1 protein 0.0135 0.0556 0.0556
Brugia malayi celfurPC protein 0.1057 0.5843 0.5836
Brugia malayi hypothetical protein 0.0136 0.0562 0.0544
Loa Loa (eye worm) melatonin receptor type 1A 0.0136 0.0562 0.0562
Leishmania major beta tubulin 0.0135 0.0556 1
Brugia malayi ORL1-like opioid receptor 0.0136 0.0562 0.0544
Echinococcus multilocularis neuropeptides capa receptor 0.0136 0.0562 0.0544
Schistosoma mansoni neuropeptide f receptor 76f 0.0136 0.0562 0.0727
Echinococcus multilocularis cyclin B 0.0073 0.0196 0.0178
Loa Loa (eye worm) hypothetical protein 0.0136 0.0562 0.0562
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0136 0.0562 0.0544
Onchocerca volvulus 0.0136 0.0562 0.5334
Echinococcus granulosus rhodopsin orphan GPCR 0.0136 0.0562 0.0544
Schistosoma mansoni hypothetical protein 0.0286 0.1423 0.188
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0136 0.0562 0.0544
Trichomonas vaginalis tubulin beta chain, putative 0.0135 0.0556 0.1338
Toxoplasma gondii beta-1 tubulin, putative 0.0135 0.0556 1
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0136 0.0562 0.0544
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0136 0.0562 0.0727
Brugia malayi Dopamine receptor protein 2 0.0136 0.0562 0.0544
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0136 0.0562 0.0544
Loa Loa (eye worm) hypothetical protein 0.0136 0.0562 0.0562
Loa Loa (eye worm) hypothetical protein 0.0136 0.0562 0.0562
Echinococcus multilocularis neuropeptide Y receptor 0.0136 0.0562 0.0544
Loa Loa (eye worm) hypothetical protein 0.0136 0.0562 0.0562
Loa Loa (eye worm) hypothetical protein 0.0136 0.0562 0.0562
Echinococcus granulosus rhodopsin orphan GPCR 0.0136 0.0562 0.0544
Schistosoma mansoni opsin-like receptor 0.0136 0.0562 0.0727
Echinococcus multilocularis cyclin dependent kinase 5 0.0042 0.0021 0.0002
Echinococcus multilocularis rhodopsin orphan GPCR 0.0136 0.0562 0.0544
Brugia malayi hypothetical protein 0.0136 0.0562 0.0544
Loa Loa (eye worm) beta-tubulin 0.0135 0.0556 0.0556
Echinococcus granulosus allatostatin A receptor 0.0136 0.0562 0.0544
Brugia malayi putative neuropeptide receptor 0.0136 0.0562 0.0544
Trichomonas vaginalis retinoblastoma binding protein, putative 0.0072 0.0193 0.0465
Echinococcus granulosus neuropeptide receptor 0.0136 0.0562 0.0544
Echinococcus granulosus tm gpcr rhodopsin 0.1677 0.9404 0.9403
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0063 0.0142 0.0343
Brugia malayi Subtilase family protein 0.0063 0.0142 0.0124
Brugia malayi G-protein coupled receptor 0.0136 0.0562 0.0544
Brugia malayi Protein kinase domain containing protein 0.0078 0.0224 0.0206
Trichomonas vaginalis conserved hypothetical protein 0.0072 0.0193 0.0465
Plasmodium falciparum tubulin beta chain 0.0135 0.0556 1
Echinococcus multilocularis Peptidase S8 S53, subtilisin kexin sedolisin 0.0063 0.0142 0.0124
Echinococcus multilocularis 0.1057 0.5843 0.5836
Echinococcus multilocularis neuropeptide s receptor 0.0136 0.0562 0.0544
Plasmodium vivax subtilisin-like protease 2, putative 0.0063 0.0142 0.2299
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0042 0.0021 0.0021
Echinococcus granulosus g protein coupled receptor 0.0136 0.0562 0.0544
Onchocerca volvulus 0.0136 0.0562 0.5334
Onchocerca volvulus 0.02 0.093 1
Brugia malayi Will die slowly protein 0.0068 0.0168 0.0149
Onchocerca volvulus 0.0136 0.0562 0.5334
Schistosoma mansoni serine/threonine protein kinase 0.0042 0.0021 0.0002
Trichomonas vaginalis cyclins, putative 0.0073 0.0196 0.0473
Schistosoma mansoni tubulin subunit beta 0.0135 0.0556 0.0719
Toxoplasma gondii subtilisin SUB9 0.0063 0.0142 0.2564
Echinococcus multilocularis tubulin beta 1 chain 0.0135 0.0556 0.0538
Loa Loa (eye worm) hypothetical protein 0.0136 0.0562 0.0562
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0042 0.0021 0.0021
Echinococcus multilocularis orexin receptor type 2 0.0136 0.0562 0.0544
Loa Loa (eye worm) subtilase 0.0063 0.0142 0.0142
Brugia malayi beta-tubulin, identical 0.0135 0.0556 0.0538
Trichomonas vaginalis conserved hypothetical protein 0.0286 0.1423 0.3425
Trypanosoma brucei beta tubulin 0.0135 0.0556 1
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0136 0.0562 0.0562
Trichomonas vaginalis cyclin A, putative 0.0073 0.0196 0.0473
Loa Loa (eye worm) hypothetical protein 0.0136 0.0562 0.0562
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0063 0.0142 0.0343
Loa Loa (eye worm) hypothetical protein 0.1781 1 1
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.0087 0.0277 0.0345
Echinococcus multilocularis Tubulin beta 2C chain 0.0135 0.0556 0.0538
Echinococcus granulosus tubulin beta 4A class IVa 0.0135 0.0556 0.0538
Brugia malayi Serotonin receptor 0.0136 0.0562 0.0544
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0135 0.0556 0.0538
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0136 0.0562 0.5334
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0063 0.0142 0.0343
Echinococcus granulosus dnaJ subfamily B 0.04 0.2074 0.2059
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0136 0.0562 0.0544
Echinococcus granulosus neuropeptide Y receptor 0.0136 0.0562 0.0544
Schistosoma mansoni amine GPCR 0.0136 0.0562 0.0727
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0136 0.0562 0.0544
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0063 0.0142 0.0343
Brugia malayi Dopamine receptor protein 1 0.0136 0.0562 0.0544
Echinococcus granulosus g protein coupled receptor 0.0136 0.0562 0.0544
Echinococcus multilocularis dro:myosuppressin receptor 0.0136 0.0562 0.0544
Echinococcus multilocularis G-protein coupled receptor, putative 0.0136 0.0562 0.0544
Leishmania major subtilisin-like serine peptidase 0.0063 0.0142 0.2274
Mycobacterium ulcerans membrane-anchored serine protease (mycosin), MycP4 0.0063 0.0142 0.5
Echinococcus multilocularis Tubulin beta 2C chain 0.0135 0.0556 0.0538
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0373 0.192 0.4622
Brugia malayi Protein kinase domain containing protein 0.0042 0.0021 0.0002
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0136 0.0562 0.0727
Schistosoma mansoni biogenic amine receptor 0.0136 0.0562 0.0727
Loa Loa (eye worm) endoprotease bli-4 0.1343 0.7487 0.7487
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0019 0.0046
Loa Loa (eye worm) hypothetical protein 0.0136 0.0562 0.0562
Echinococcus granulosus biogenic amine 5HT receptor 0.0136 0.0562 0.0544
Brugia malayi Hypothetical subtilase-type proteinase F21H12.6 in chromosome II 0.0063 0.0142 0.0124
Leishmania major beta tubulin 0.0135 0.0556 1
Brugia malayi G protein-coupled receptor 0.0136 0.0562 0.0544
Onchocerca volvulus 0.0136 0.0562 0.5334
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0136 0.0562 0.0727
Loa Loa (eye worm) hypothetical protein 0.0136 0.0562 0.0562
Loa Loa (eye worm) hypothetical protein 0.0136 0.0562 0.0562
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0136 0.0562 0.0544
Onchocerca volvulus 0.0136 0.0562 0.5334
Loa Loa (eye worm) hypothetical protein 0.0136 0.0562 0.0562
Trichomonas vaginalis conserved hypothetical protein 0.0286 0.1423 0.3425
Loa Loa (eye worm) hypothetical protein 0.0136 0.0562 0.0562
Loa Loa (eye worm) hypothetical protein 0.0136 0.0562 0.0562
Brugia malayi endoprotease bli-4 precursor 0.1343 0.7487 0.7482
Echinococcus granulosus proprotein convertase subtilisin:kexin type 5 0.0762 0.4154 0.4143
Loa Loa (eye worm) hypothetical protein 0.0136 0.0562 0.0562
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0136 0.0562 0.0544
Trypanosoma cruzi subtilisin peptidase 0.0063 0.0142 0.2274
Leishmania major beta tubulin 0.0135 0.0556 1
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0136 0.0562 0.0544
Leishmania major beta tubulin 0.0135 0.0556 1
Echinococcus granulosus peptide allatostatin:somatostatin 0.0136 0.0562 0.0544
Trichomonas vaginalis neuroendocrine convertase 2 precursor, putative 0.031 0.1557 0.3748
Echinococcus granulosus sex peptide receptor 0.0136 0.0562 0.0544
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0063 0.0142 0.0343
Loa Loa (eye worm) hypothetical protein 0.0136 0.0562 0.0562
Trichomonas vaginalis conserved hypothetical protein 0.0286 0.1423 0.3425
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0136 0.0562 0.0727
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0136 0.0562 0.0562
Brugia malayi Dopamine receptor 0.0136 0.0562 0.0544
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0136 0.0562 0.0544
Loa Loa (eye worm) hypothetical protein 0.0063 0.0142 0.0142
Trichomonas vaginalis cyclin B, putative 0.0073 0.0196 0.0473
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0136 0.0562 0.0544
Echinococcus multilocularis neuropeptide FF receptor 2 0.1781 1 1
Echinococcus granulosus tubulin subunit beta 0.0135 0.0556 0.0538
Trichomonas vaginalis conserved hypothetical protein 0.0286 0.1423 0.3425
Schistosoma mansoni growth hormone secretagogue receptor 0.0136 0.0562 0.0727
Schistosoma mansoni histamine h1 receptor 0.0136 0.0562 0.0727
Echinococcus granulosus cyclin dependent kinase 1 0.0042 0.0021 0.0002
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0136 0.0562 0.0727
Trichomonas vaginalis cyclins, putative 0.0073 0.0196 0.0473
Brugia malayi proprotein convertase 2 0.0954 0.5253 0.5244
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0136 0.0562 0.0727
Echinococcus granulosus Tubulin beta 2C chain 0.0135 0.0556 0.0538
Brugia malayi Melatonin receptor type 1A 0.0136 0.0562 0.0544
Loa Loa (eye worm) neuropeptide F receptor 0.0136 0.0562 0.0562
Trichomonas vaginalis cyclins, putative 0.0073 0.0196 0.0473
Echinococcus multilocularis neuroendocrine convertase 2 0.0954 0.5253 0.5244
Trypanosoma cruzi subtilisin-like serine peptidase, putative 0.0063 0.0142 0.2274
Toxoplasma gondii subtilisin SUB7 0.0063 0.0142 0.2564
Schistosoma mansoni neuropeptide F-like receptor 0.0136 0.0562 0.0727
Trichomonas vaginalis conserved hypothetical protein 0.0286 0.1423 0.3425
Echinococcus granulosus orexin receptor type 2 0.0136 0.0562 0.0544
Echinococcus multilocularis proprotein convertase subtilisin:kexin type 5 0.0762 0.4154 0.4143
Schistosoma mansoni site-1 peptidase (S08 family) 0.0063 0.0142 0.0165
Schistosoma mansoni biogenic amine receptor 0.0136 0.0562 0.0727
Leishmania major beta tubulin 0.0135 0.0556 1
Brugia malayi neuropeptide F receptor 0.0136 0.0562 0.0544
Leishmania major beta tubulin 0.0135 0.0556 1
Leishmania major beta tubulin 0.0135 0.0556 1
Echinococcus multilocularis g protein coupled receptor 0.0136 0.0562 0.0544
Echinococcus granulosus neuropeptide receptor 0.0136 0.0562 0.0544
Echinococcus multilocularis neuropeptide Y receptor 0.0136 0.0562 0.0544
Brugia malayi hypothetical protein 0.0136 0.0562 0.0544
Echinococcus multilocularis cyclin dependent kinase 0.0042 0.0021 0.0002
Toxoplasma gondii subtilisin SUB10 0.0063 0.0142 0.2564
Brugia malayi hypothetical protein 0.0136 0.0562 0.0544
Toxoplasma gondii subtilisin SUB4 0.0063 0.0142 0.2564
Trichomonas vaginalis CMGC family protein kinase 0.0042 0.0021 0.005
Schistosoma mansoni serine/threonine protein kinase 0.0042 0.0021 0.0002
Loa Loa (eye worm) tubulin beta chain 0.0135 0.0556 0.0556
Schistosoma mansoni tubulin subunit beta 0.0135 0.0556 0.0719
Echinococcus granulosus beta tubulin 0.0135 0.0556 0.0538
Schistosoma mansoni hypothetical protein 0.0136 0.0562 0.0727
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0136 0.0562 0.0544
Echinococcus granulosus Tubulin beta 2C chain 0.0135 0.0556 0.0538
Schistosoma mansoni tubulin subunit beta 0.0135 0.0556 0.0719
Schistosoma mansoni tripeptidyl-peptidase II (S08 family) 0.0063 0.0142 0.0165
Echinococcus granulosus 7TM GPCR rhodopsin 0.0136 0.0562 0.0544
Schistosoma mansoni site-1 peptidase (S08 family) 0.0063 0.0142 0.0165
Loa Loa (eye worm) BEN-1 protein 0.0135 0.0556 0.0556
Trichomonas vaginalis conserved hypothetical protein 0.0286 0.1423 0.3425
Echinococcus granulosus Furin 1 0.0373 0.192 0.1905
Loa Loa (eye worm) hypothetical protein 0.0073 0.0196 0.0196
Echinococcus granulosus neuropeptides capa receptor 0.0136 0.0562 0.0544
Echinococcus granulosus dro:myosuppressin receptor 0.0136 0.0562 0.0544
Echinococcus granulosus tachykinin peptides receptor 99D 0.0136 0.0562 0.0544
Echinococcus multilocularis neuropeptides capa receptor 0.0136 0.0562 0.0544
Toxoplasma gondii subtilisin SUB11 0.0063 0.0142 0.2564
Toxoplasma gondii subtilisin SUB12 0.0091 0.0302 0.5433
Loa Loa (eye worm) hypothetical protein 0.0136 0.0562 0.0562
Leishmania major beta tubulin 0.0135 0.0556 1
Leishmania major beta tubulin 0.0135 0.0556 1
Mycobacterium ulcerans membrane-anchored mycosin MycP3 0.0063 0.0142 0.5
Trypanosoma brucei mitotic cyclin 6 0.0073 0.0196 0.3282
Echinococcus granulosus beta tubulin 0.0135 0.0556 0.0538
Schistosoma mansoni neuropeptide receptor 0.0136 0.0562 0.0727
Leishmania major beta tubulin 0.0135 0.0556 1
Brugia malayi G-protein coupled receptor 0.0136 0.0562 0.0544
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.1343 0.7487 1
Entamoeba histolytica tubulin family protein 0.0135 0.0556 1
Plasmodium vivax tubulin beta chain, putative 0.0135 0.0556 1
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0136 0.0562 0.0544
Echinococcus multilocularis wd40 repeat 0.0072 0.0193 0.0175
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0042 0.0021 0.0375
Echinococcus granulosus tissue type plasminogen activator 0.0078 0.0224 0.0206
Onchocerca volvulus 0.0136 0.0562 0.5334
Brugia malayi hypothetical protein 0.0136 0.0562 0.0544
Plasmodium falciparum subtilisin-like protease 1 0.0063 0.0142 0.2299
Echinococcus multilocularis rhodopsin orphan GPCR 0.0136 0.0562 0.0544
Trypanosoma brucei subtilisin peptidase 0.0063 0.0142 0.2274
Loa Loa (eye worm) G-protein coupled receptor 0.0136 0.0562 0.0562
Echinococcus granulosus tm gpcr rhodopsin 0.0136 0.0562 0.0544
Loa Loa (eye worm) hypothetical protein 0.0136 0.0562 0.0562
Toxoplasma gondii subtilisin SUB2 0.0063 0.0142 0.2564
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0762 0.4154 1
Schistosoma mansoni myosin xvIII 0.0136 0.0562 0.0727
Echinococcus granulosus cyclin dependent kinase 5 0.0042 0.0021 0.0002
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0136 0.0562 0.0727
Giardia lamblia Beta tubulin 0.0135 0.0556 0.2515
Trichomonas vaginalis proprotein convertase subtilisin/kexin type, putative 0.031 0.1557 0.3748
Echinococcus multilocularis Tubulin beta 2C chain 0.0135 0.0556 0.0538
Schistosoma mansoni amine GPCR 0.0136 0.0562 0.0727
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0136 0.0562 0.0727
Leishmania major beta tubulin 0.0135 0.0556 1
Onchocerca volvulus 0.0136 0.0562 0.5334
Loa Loa (eye worm) hypothetical protein 0.0136 0.0562 0.0562
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0063 0.0142 0.0343
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0136 0.0562 0.0544
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0136 0.0562 0.0727
Loa Loa (eye worm) hypothetical protein 0.0136 0.0562 0.0562
Loa Loa (eye worm) WD40 repeat protein 0.0068 0.0168 0.0168
Echinococcus multilocularis G protein coupled receptor 139 0.0136 0.0562 0.0544
Mycobacterium tuberculosis Probable alanine and proline rich membrane-anchored mycosin MycP2 (serine protease) (subtilisin-like protease) (subtilase-like) 0.0063 0.0142 0.5
Loa Loa (eye worm) hypothetical protein 0.0136 0.0562 0.0562
Schistosoma mansoni hypothetical protein 0.04 0.2074 0.2752
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0136 0.0562 0.0727
Echinococcus granulosus neuropeptides capa receptor 0.0136 0.0562 0.0544
Loa Loa (eye worm) TK/ROR protein kinase 0.0078 0.0224 0.0224
Plasmodium falciparum subtilisin-like protease 3 0.0063 0.0142 0.2299
Brugia malayi Trypsin family protein 0.02 0.093 0.0912
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0136 0.0562 0.0727
Onchocerca volvulus 0.0136 0.0562 0.5334
Echinococcus granulosus cyclin dependent kinase 0.0042 0.0021 0.0002
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0136 0.0562 0.0544
Trichomonas vaginalis conserved hypothetical protein 0.0286 0.1423 0.3425
Schistosoma mansoni tubulin subunit beta 0.0135 0.0556 0.0719
Plasmodium falciparum subtilisin-like protease 2 0.0063 0.0142 0.2299
Schistosoma mansoni retinoblastoma binding protein 0.0072 0.0193 0.0233
Onchocerca volvulus 0.0136 0.0562 0.5334
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0136 0.0562 0.0727
Brugia malayi neuropeptide F receptor 0.0136 0.0562 0.0544
Loa Loa (eye worm) neuropeptide F receptor 0.0136 0.0562 0.0562
Loa Loa (eye worm) hypothetical protein 0.0136 0.0562 0.0562
Trichomonas vaginalis tubulin epsilon chain, putative 0.0135 0.0556 0.1338
Echinococcus granulosus g-protein coupled receptor 0.0136 0.0562 0.0544
Brugia malayi putative neuropeptide receptor NPR1 0.0136 0.0562 0.0544
Giardia lamblia Furin precursor putative serine protease 0.031 0.1557 0.7223
Echinococcus granulosus G protein coupled receptor 139 0.0136 0.0562 0.0544
Echinococcus multilocularis g-protein coupled receptor 0.0136 0.0562 0.0544
Schistosoma mansoni subfamily S8B non-peptidase homologue (S08 family) 0.0373 0.192 0.2546
Trichomonas vaginalis conserved hypothetical protein 0.0286 0.1423 0.3425
Plasmodium falciparum cysteine repeat modular protein 1 0.0078 0.0224 0.3822
Echinococcus multilocularis rhodopsin orphan GPCR 0.0136 0.0562 0.0544
Trichomonas vaginalis conserved hypothetical protein 0.0063 0.0142 0.0343
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0136 0.0562 0.0727
Loa Loa (eye worm) hypothetical protein 0.0136 0.0562 0.0562
Trichomonas vaginalis hypothetical protein 0.0286 0.1423 0.3425
Echinococcus multilocularis membrane bound transcription factor site 1 0.0063 0.0142 0.0124
Loa Loa (eye worm) tubulin beta-1 chain 0.0135 0.0556 0.0556
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0136 0.0562 0.0727
Brugia malayi G protein-coupled receptor F59B2.13 0.0136 0.0562 0.0544
Brugia malayi hypothetical protein 0.0136 0.0562 0.0544
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0136 0.0562 0.0727
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0136 0.0562 0.0727
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0063 0.0142 0.0343
Loa Loa (eye worm) hypothetical protein 0.0136 0.0562 0.0562
Echinococcus multilocularis epidermal growth factor receptor 0.0123 0.0484 0.0466
Echinococcus multilocularis tissue type plasminogen activator 0.0078 0.0224 0.0206
Schistosoma mansoni opsin-like receptor 0.0136 0.0562 0.0727
Schistosoma mansoni tubulin subunit beta 0.0135 0.0556 0.0719
Mycobacterium leprae PROBABLE PROLINE RICH MEMBRANE-ANCHORED MYCOSIN MYCP5 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-5) 0.0063 0.0142 0.5
Onchocerca volvulus 0.0078 0.0224 0.1038
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0063 0.0142 0.0343
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0136 0.0562 0.0727
Echinococcus granulosus protein will die slowly 0.0068 0.0168 0.0149
Trichomonas vaginalis tubulin alpha chain, putative 0.0135 0.0556 0.1338
Trypanosoma cruzi cyclin, putative 0.0073 0.0196 0.3282
Loa Loa (eye worm) hypothetical protein 0.0136 0.0562 0.0562
Trypanosoma brucei serine peptidase, clan SB, family S8-like protein 0.0063 0.0142 0.2274
Echinococcus multilocularis neuropeptide receptor 0.0136 0.0562 0.0544
Echinococcus multilocularis fmrfamide receptor 0.0136 0.0562 0.0544
Trypanosoma cruzi beta tubulin, putative 0.0135 0.0556 1
Trichomonas vaginalis cyclin B, putative 0.0073 0.0196 0.0473
Brugia malayi Serotonin receptor 0.0136 0.0562 0.0544
Leishmania major cyclin 0.0073 0.0196 0.3282
Schistosoma mansoni neuropeptide F-like receptor 0.0136 0.0562 0.0727
Loa Loa (eye worm) hypothetical protein 0.0136 0.0562 0.0562
Leishmania major hypothetical protein, conserved 0.0078 0.0224 0.3802
Schistosoma mansoni amine GPCR 0.0136 0.0562 0.0727
Loa Loa (eye worm) hypothetical protein 0.0136 0.0562 0.0562
Brugia malayi Tubulin beta-1 chain 0.0135 0.0556 0.0538
Toxoplasma gondii beta tubulin 0.0135 0.0556 1
Loa Loa (eye worm) hypothetical protein 0.0136 0.0562 0.0562
Onchocerca volvulus 0.0136 0.0562 0.5334
Onchocerca volvulus 0.0136 0.0562 0.5334
Trichomonas vaginalis conserved hypothetical protein 0.0063 0.0142 0.0343
Loa Loa (eye worm) proprotein convertase 2 0.0373 0.192 0.192
Trichomonas vaginalis cyclin B, putative 0.0073 0.0196 0.0473
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0136 0.0562 0.0727
Schistosoma mansoni biogenic amine (5HT) receptor 0.0136 0.0562 0.0727
Onchocerca volvulus 0.0073 0.0196 0.0685
Loa Loa (eye worm) hypothetical protein 0.0136 0.0562 0.0562
Toxoplasma gondii beta-tubulin, putative 0.0135 0.0556 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0136 0.0562 0.0544
Echinococcus granulosus cyclin B 0.0073 0.0196 0.0178
Trypanosoma brucei beta tubulin 0.0135 0.0556 1
Echinococcus granulosus epidermal growth factor receptor 0.0123 0.0484 0.0466
Echinococcus multilocularis beta tubulin 0.0135 0.0556 0.0538
Loa Loa (eye worm) TK/EGFR protein kinase 0.0123 0.0484 0.0484
Brugia malayi Furin-like cysteine rich region family protein 0.0123 0.0484 0.0466
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0373 0.192 0.4622
Plasmodium falciparum protein kinase 5 0.0042 0.0021 0.0033
Brugia malayi follicle stimulating hormone receptor 0.0136 0.0562 0.0544
Echinococcus granulosus wd40 repeat 0.0072 0.0193 0.0175
Onchocerca volvulus 0.0136 0.0562 0.5334
Echinococcus multilocularis neuropeptide receptor 0.0136 0.0562 0.0544
Leishmania major beta tubulin 0.0135 0.0556 1
Giardia lamblia G2/mitotic-specific cyclin B 0.0073 0.0196 0.0825
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0136 0.0562 0.0544
Trichomonas vaginalis cyclins, putative 0.0073 0.0196 0.0473
Echinococcus multilocularis serotonin receptor 0.0136 0.0562 0.0544
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0136 0.0562 0.0544
Loa Loa (eye worm) hypothetical protein 0.0136 0.0562 0.0562
Schistosoma mansoni hypothetical protein 0.0078 0.0224 0.0275
Echinococcus multilocularis serotonin receptor 0.0136 0.0562 0.0544
Loa Loa (eye worm) hypothetical protein 0.0136 0.0562 0.0562
Toxoplasma gondii kringle domain-containing protein 0.0078 0.0224 0.4034
Plasmodium vivax protein kinase Crk2 0.0042 0.0021 0.0033
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0136 0.0562 0.0544
Echinococcus multilocularis rhodopsin orphan GPCR 0.0136 0.0562 0.0544
Schistosoma mansoni amine GPCR 0.0136 0.0562 0.0727
Trichomonas vaginalis leucine-rich repeat protein, BspA family 0.0286 0.1423 0.3425
Echinococcus multilocularis somatostatin receptor 0.0136 0.0562 0.0544
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0063 0.0142 0.0343
Echinococcus multilocularis g protein coupled receptor 0.0136 0.0562 0.0544
Schistosoma mansoni hypothetical protein 0.0136 0.0562 0.0727
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0136 0.0562 0.0544
Mycobacterium ulcerans proline rich membrane-anchored mycosin MycP5 0.0063 0.0142 0.5
Echinococcus multilocularis g protein coupled receptor 0.0136 0.0562 0.0544
Schistosoma mansoni biogenic amine receptor 0.0136 0.0562 0.0727
Onchocerca volvulus 0.0136 0.0562 0.5334
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0136 0.0562 0.0727
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0136 0.0562 0.0544
Echinococcus multilocularis allatostatin A receptor 0.0136 0.0562 0.0544
Echinococcus multilocularis tubulin subunit beta 0.0135 0.0556 0.0538
Giardia lamblia Beta tubulin 0.0135 0.0556 0.2515
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0063 0.0142 0.0343
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0063 0.0142 0.0343
Toxoplasma gondii subtilisin SUB6 0.0063 0.0142 0.2564
Echinococcus multilocularis rhodopsin orphan GPCR 0.0136 0.0562 0.0544
Schistosoma mansoni neuropeptide receptor 0.0136 0.0562 0.0727
Schistosoma mansoni alpha-1 adrenergic receptor 0.0136 0.0562 0.0727
Schistosoma mansoni hypothetical protein 0.0068 0.0168 0.0199
Echinococcus multilocularis beta tubulin 0.0135 0.0556 0.0538
Loa Loa (eye worm) hypothetical protein 0.0042 0.0023 0.0023
Echinococcus granulosus rhodopsin orphan GPCR 0.0136 0.0562 0.0544
Trichomonas vaginalis conserved hypothetical protein 0.0286 0.1423 0.3425
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0063 0.0142 0.0343
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0063 0.0142 0.0343
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0136 0.0562 0.0727
Echinococcus granulosus membrane bound transcription factor site 1 0.0063 0.0142 0.0124
Trypanosoma cruzi hypothetical protein, conserved 0.0078 0.0224 0.3802
Loa Loa (eye worm) hypothetical protein 0.0136 0.0562 0.0562
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0019 0.0046
Plasmodium vivax subtilisin-like protease 1 0.0063 0.0142 0.2299
Loa Loa (eye worm) hypothetical protein 0.0136 0.0562 0.0562
Brugia malayi Hypothetical WD-repeat protein F21H12.1 in chromosome II 0.0072 0.0193 0.0175
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0063 0.0142 0.0343
Schistosoma mansoni furin-1 (S08 family) 0.0644 0.3475 0.4628
Loa Loa (eye worm) hypothetical protein 0.0136 0.0562 0.0562
Trichomonas vaginalis tubulin gamma chain, putative 0.0135 0.0556 0.1338
Echinococcus granulosus g protein coupled receptor 0.0136 0.0562 0.0544
Loa Loa (eye worm) hypothetical protein 0.0136 0.0562 0.0562
Brugia malayi GnHR receptor homolog 0.0136 0.0562 0.0544
Schistosoma mansoni neuropeptide receptor 0.0136 0.0562 0.0727
Leishmania major beta tubulin 0.0135 0.0556 1
Brugia malayi hypothetical protein 0.0136 0.0562 0.0544
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0063 0.0142 0.0343
Loa Loa (eye worm) hypothetical protein 0.0136 0.0562 0.0562
Echinococcus multilocularis sex peptide receptor 0.0136 0.0562 0.0544
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0087 0.0277 0.0666
Schistosoma mansoni tyrosine kinase 0.0123 0.0484 0.0622
Loa Loa (eye worm) SPRY domain-containing protein 0.0042 0.0019 0.0019
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0063 0.0142 0.0343
Echinococcus multilocularis protein will die slowly 0.0068 0.0168 0.0149
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0136 0.0562 0.0544
Echinococcus granulosus neuropeptide receptor A26 0.0136 0.0562 0.0544
Loa Loa (eye worm) TYRA-2 protein 0.0136 0.0562 0.0562
Schistosoma mansoni cyclin B 0.0073 0.0196 0.0237
Echinococcus granulosus Tubulin beta 2C chain 0.0135 0.0556 0.0538
Trichomonas vaginalis tubulin epsilon chain, putative 0.0135 0.0556 0.1338
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0762 0.4154 1
Toxoplasma gondii subtilisin SUB8 0.0063 0.0142 0.2564
Mycobacterium leprae Possible secreted protease 0.0063 0.0142 0.5
Leishmania major beta tubulin 0.0135 0.0556 1
Loa Loa (eye worm) G-protein coupled receptor 0.0136 0.0562 0.0562
Loa Loa (eye worm) hypothetical protein 0.0136 0.0562 0.0562
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0136 0.0562 0.0544
Loa Loa (eye worm) hypothetical protein 0.0136 0.0562 0.0562
Plasmodium vivax subtilisin-like serine protease, putative 0.0063 0.0142 0.2299
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0136 0.0562 0.0544
Loa Loa (eye worm) hypothetical protein 0.0136 0.0562 0.0562
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0042 0.0021 0.0002
Loa Loa (eye worm) hypothetical protein 0.0136 0.0562 0.0562
Echinococcus granulosus 7tm_1 domain containing protein 0.0136 0.0562 0.0544
Echinococcus multilocularis cyclin dependent kinase 1 0.0042 0.0021 0.0002
Leishmania major beta tubulin 0.0135 0.0556 1
Echinococcus granulosus furin 0.1343 0.7487 0.7482
Giardia lamblia Beta tubulin 0.0135 0.0556 0.2515
Leishmania major CYC2-like cyclin, putative,cyclin 6, putative 0.0073 0.0196 0.3282
Trichomonas vaginalis CMGC family protein kinase 0.0042 0.0021 0.005
Brugia malayi hypothetical protein 0.0136 0.0562 0.0544
Loa Loa (eye worm) hypothetical protein 0.0042 0.0018 0.0018
Echinococcus granulosus neuropeptide Y receptor 0.0136 0.0562 0.0544
Echinococcus multilocularis rhodopsin orphan GPCR 0.0136 0.0562 0.0544
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0063 0.0142 0.0343
Brugia malayi sulfakinin receptor protein 0.0136 0.0562 0.0544
Echinococcus granulosus rhodopsin orphan GPCR 0.0136 0.0562 0.0544
Echinococcus granulosus rhodopsin orphan GPCR 0.0136 0.0562 0.0544
Loa Loa (eye worm) hypothetical protein 0.0136 0.0562 0.0562
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.02 0.093 0.1219
Loa Loa (eye worm) hypothetical protein 0.02 0.093 0.093
Echinococcus granulosus tubulin beta 1 chain 0.0135 0.0556 0.0538
Loa Loa (eye worm) hypothetical protein 0.0171 0.0763 0.0763
Onchocerca volvulus 0.0136 0.0562 0.5334
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0063 0.0142 0.0343
Onchocerca volvulus Neuropeptide F receptor homolog 0.0136 0.0562 0.5334
Trichomonas vaginalis CMGC family protein kinase 0.0042 0.0021 0.005
Loa Loa (eye worm) hypothetical protein 0.0073 0.0196 0.0196
Leishmania major beta tubulin 0.0135 0.0556 1
Entamoeba histolytica tubulin family protein 0.0135 0.0556 1
Brugia malayi AKH receptor 0.0136 0.0562 0.0544
Echinococcus granulosus serotonin receptor 0.0136 0.0562 0.0544
Brugia malayi Kringle domain containing protein 0.0078 0.0224 0.0206
Brugia malayi cell division control protein 2 homolog 0.0042 0.0021 0.0002
Echinococcus granulosus rhodopsin orphan GPCR 0.0136 0.0562 0.0544
Trypanosoma cruzi CYC2-like cyclin, putative 0.0073 0.0196 0.3282
Trypanosoma cruzi subtilisin-like serine peptidase, putative 0.0063 0.0142 0.2274
Toxoplasma gondii subtilisin SUB1 0.0063 0.0142 0.2564
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0063 0.0142 0.0343
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0373 0.192 0.4622
Echinococcus multilocularis fmrfamide receptor 0.0136 0.0562 0.0544
Echinococcus granulosus neuropeptide FF receptor 2 0.1781 1 1
Schistosoma mansoni amine GPCR 0.0136 0.0562 0.0727
Onchocerca volvulus 0.0173 0.0771 0.7982
Trichomonas vaginalis conserved hypothetical protein 0.0286 0.1423 0.3425
Schistosoma mansoni opsin-like receptor 0.0136 0.0562 0.0727
Echinococcus multilocularis Furin 1 0.0373 0.192 0.1905
Schistosoma mansoni hypothetical protein 0.0136 0.0562 0.0727
Brugia malayi hypothetical protein 0.0136 0.0562 0.0544
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0136 0.0562 0.0727
Echinococcus granulosus fmrfamide receptor 0.0136 0.0562 0.0544
Loa Loa (eye worm) tubulin beta-2A chain 0.0135 0.0556 0.0556
Brugia malayi Cyclin, N-terminal domain containing protein 0.0073 0.0196 0.0178
Brugia malayi neuroendocrine convertase 1 precursor 0.1102 0.6102 0.6095
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0063 0.0142 0.0343
Onchocerca volvulus 0.0136 0.0562 0.5334
Mycobacterium leprae PROBABLE MEMBRANE-ANCHORED MYCOSIN MYCP3 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-3) 0.0063 0.0142 0.5
Loa Loa (eye worm) tubulin beta-4 chain 0.0135 0.0556 0.0556
Mycobacterium tuberculosis Probable proline rich membrane-anchored mycosin MycP5 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-5) 0.0063 0.0142 0.5
Loa Loa (eye worm) hypothetical protein 0.0078 0.0224 0.0224
Trypanosoma cruzi serine peptidase, clan SB, family S8-like protein 0.0063 0.0142 0.2274
Trichomonas vaginalis conserved hypothetical protein 0.0063 0.0142 0.0343
Schistosoma mansoni tubulin subunit beta 0.0135 0.0556 0.0719
Mycobacterium tuberculosis Probable membrane-anchored mycosin MycP4 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-4) 0.0063 0.0142 0.5
Echinococcus multilocularis rhodopsin orphan GPCR 0.0136 0.0562 0.0544
Echinococcus granulosus hypothetical protein 0.0136 0.0562 0.0544

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 2.18 ug ml-1 Cytotoxicity against human OVCAR3 cells assessed as growth inhibition after 24 hrs by MTT assay ChEMBL. 24447851

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23 24447851

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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