Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | beta-NAC-like protein | 0.0036 | 0.0365 | 0.0375 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0035 | 0.0344 | 0.0353 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0344 | 0.0353 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0036 | 0.0365 | 0.5 |
Trypanosoma cruzi | transcription factor btf3, putative | 0.0036 | 0.0365 | 0.5 |
Schistosoma mansoni | transcription factor btf3 | 0.0036 | 0.0365 | 0.1014 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0036 | 0.0365 | 0.5 |
Trypanosoma brucei | transcription factor BTF3, putative | 0.0036 | 0.0365 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0723 | 0.0742 |
Plasmodium vivax | basic transcription factor 3b, putative | 0.0036 | 0.0365 | 0.5 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0052 | 0.0723 | 0.0742 |
Loa Loa (eye worm) | hypothetical protein | 0.0432 | 0.9524 | 0.977 |
Trypanosoma cruzi | transcription factor btf3, putative | 0.0036 | 0.0365 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0365 | 0.5 |
Loa Loa (eye worm) | ICD-1 protein | 0.0036 | 0.0365 | 0.0375 |
Plasmodium falciparum | basic transcription factor 3b, putative | 0.0036 | 0.0365 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0344 | 0.0955 |
Echinococcus granulosus | geminin | 0.0176 | 0.36 | 1 |
Toxoplasma gondii | NAC domain-containing protein | 0.0036 | 0.0365 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0036 | 0.0365 | 0.5 |
Echinococcus multilocularis | transcription factor btf3 | 0.0036 | 0.0365 | 0.1014 |
Brugia malayi | nuclear hormone receptor | 0.0441 | 0.9749 | 1 |
Entamoeba histolytica | transcription factor BTF3, putative | 0.0036 | 0.0365 | 0.5 |
Echinococcus granulosus | transcription factor btf3 | 0.0036 | 0.0365 | 0.1014 |
Echinococcus multilocularis | geminin | 0.0176 | 0.36 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0176 | 0.36 | 1 |
Leishmania major | basic transcription factor 3a, putative | 0.0036 | 0.0365 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0176 | 0.36 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0052 | 0.0723 | 0.0742 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0052 | 0.0723 | 0.0742 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0441 | 0.9749 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.