Detailed information for compound 1834892

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 486.597 | Formula: C28H38O7
  • H donors: 1 H acceptors: 5 LogP: 3.35 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(=O)O[C@@H]1[C@H](O)[C@@H]2[C@]([C@@H]3[C@]1(C)C1=CC[C@H]([C@]1(C)CC3)[C@@H]1CC(=O)OC1=O)(C)CCC(=O)C2(C)C
  • InChi: 1S/C28H38O7/c1-14(29)34-23-21(32)22-25(2,3)19(30)10-12-27(22,5)18-9-11-26(4)16(7-8-17(26)28(18,23)6)15-13-20(31)35-24(15)33/h8,15-16,18,21-23,32H,7,9-13H2,1-6H3/t15-,16-,18+,21+,22-,23+,26-,27+,28-/m0/s1
  • InChiKey: PQZZUIASTCSMGQ-DXLZGUMWSA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Trypanosoma brucei glucose transporter, putative 0.0033 0.0294 0.0432
Leishmania major glucose transporter/membrane transporter D2, putative 0.0033 0.0294 0.0432
Brugia malayi dihydrofolate reductase family protein 0.0236 0.3258 0.9074
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.023 0.0309
Trypanosoma brucei glucose transporter, putative 0.0033 0.0294 0.0432
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.069 0.0669
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0062 0.0713 0.0687
Echinococcus granulosus methyl CpG binding domain protein 2 0.0018 0.0076 0.0048
Plasmodium vivax CDK-related protein kinase 6, putative 0.0457 0.6479 0.9822
Loa Loa (eye worm) dihydrofolate reductase 0.0236 0.3258 0.9074
Toxoplasma gondii ABC1 family protein 0.0073 0.0871 0.1285
Brugia malayi Intermediate filament tail domain containing protein 0.0025 0.0173 0.0474
Trypanosoma brucei glucose transporter 1E 0.0033 0.0294 0.0432
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0089 0.0122
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0027 0.0071
Onchocerca volvulus 0.0015 0.0027 0.0059
Loa Loa (eye worm) hypothetical protein 0.0024 0.0157 0.0438
Loa Loa (eye worm) hypothetical protein 0.0073 0.0871 0.2427
Brugia malayi Bromodomain containing protein 0.0035 0.0324 0.0895
Onchocerca volvulus 0.0073 0.0871 0.275
Chlamydia trachomatis dihydrofolate reductase 0.0236 0.3258 1
Brugia malayi CHE-14 protein 0.0073 0.0869 0.2416
Schistosoma mansoni hypothetical protein 0.002 0.0099 0.0077
Schistosoma mansoni cpg binding protein 0.0021 0.0117 0.0095
Loa Loa (eye worm) jmjC domain-containing protein 0.0038 0.0367 0.1024
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0027 0.0071
Schistosoma mansoni alpha-glucosidase 0.0144 0.1915 0.1897
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0168 0.2256 0.6283
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.0871 0.3336
Leishmania major glucose transporter, lmgt2 0.0033 0.0294 0.0432
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0019 0.0082 0.006
Echinococcus multilocularis jumonji domain containing protein 0.004 0.0397 0.037
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0032 0.0281 0.0561
Loa Loa (eye worm) hypothetical protein 0.0014 0.0009 0.0025
Onchocerca volvulus 0.0015 0.0027 0.0059
Echinococcus granulosus lamin dm0 0.0025 0.0173 0.0146
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0108 0.1378 0.1354
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0174 0.235 0.3535
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.121 0.4647
Schistosoma mansoni jumonji/arid domain-containing protein 0.0038 0.0367 0.0346
Plasmodium vivax hypothetical protein, conserved 0.0073 0.0871 0.1285
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.002 0.0104 0.0117
Schistosoma mansoni hypothetical protein 0.0027 0.0206 0.0184
Giardia lamblia Prolyl-tRNA synthetase 0.0032 0.0278 0.2117
Leishmania major glucose transporter, lmgt1 0.0033 0.0294 0.0432
Schistosoma mansoni hypothetical protein 0.007 0.0831 0.0811
Schistosoma mansoni hypothetical protein 0.0022 0.0132 0.011
Entamoeba histolytica hypothetical protein 0.0064 0.0736 0.3197
Trichomonas vaginalis conserved hypothetical protein 0.0109 0.1395 0.536
Schistosoma mansoni hypothetical protein 0.007 0.0831 0.0811
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.0337 0.0958
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0026 0.018 0.0153
Schistosoma mansoni ap endonuclease 0.0019 0.0089 0.0067
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0294 0.1102
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0019 0.0082 0.0055
Echinococcus granulosus thymidylate synthase 0.0228 0.3145 0.3126
Trichomonas vaginalis penicillin-binding protein, putative 0.0073 0.0871 0.3336
Loa Loa (eye worm) hypothetical protein 0.0045 0.0458 0.1275
Echinococcus multilocularis histone acetyltransferase MYST2 0.0059 0.0663 0.0637
Loa Loa (eye worm) hypothetical protein 0.0132 0.1739 0.4845
Echinococcus granulosus zinc finger transcription factor gli2 0.0259 0.359 0.3572
Schistosoma mansoni glucose transport protein 0.0108 0.1378 0.1358
Echinococcus granulosus Niemann Pick C1 protein 0.0242 0.3345 0.3327
Echinococcus multilocularis General substrate transporter 0.0092 0.1157 0.1132
Trypanosoma brucei THT1 - hexose transporter, putative 0.0033 0.0294 0.0432
Echinococcus granulosus histone lysine methyltransferase setb 0.0019 0.0082 0.0055
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.035 0.1319
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0038 0.0356 0.0527
Trypanosoma brucei glucosidase, putative 0.0037 0.035 0.0518
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0027 0.0071
Brugia malayi major facilitator superfamily protein 0.0015 0.0027 0.0069
Schistosoma mansoni intermediate filament proteins 0.0025 0.0173 0.0151
Entamoeba histolytica hypothetical protein 0.0064 0.0736 0.3197
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0037 0.035 0.15
Leishmania major hypothetical protein, conserved 0.0015 0.0027 0.0028
Onchocerca volvulus 0.0015 0.0027 0.0059
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0095 0.1195 0.1171
Brugia malayi lysyl-tRNA synthetase 0.0024 0.0157 0.0431
Giardia lamblia Kinase, PLK 0.0096 0.121 1
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0024 0.0157 0.0573
Loa Loa (eye worm) major facilitator superfamily transporter 0.0015 0.0027 0.0076
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0089 0.0094
Echinococcus granulosus polycomb protein SCMH1 0.0052 0.0559 0.0533
Loa Loa (eye worm) acetyltransferase 0.0159 0.213 0.5934
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0062 0.0713 0.1042
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.0871 0.3336
Onchocerca volvulus Huntingtin homolog 0.0132 0.1739 0.5518
Echinococcus multilocularis lysyl tRNA synthetase 0.0024 0.0157 0.013
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0062 0.0713 0.1069
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0032 0.0278 0.0767
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0036 0.0337 1
Toxoplasma gondii isocitrate dehydrogenase 0.0062 0.0713 0.1044
Loa Loa (eye worm) latrophilin receptor protein 2 0.0027 0.0206 0.0574
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0059 0.0663 0.0637
Loa Loa (eye worm) hypothetical protein 0.0073 0.0871 0.2427
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0089 0.0122
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0096 0.121 0.3371
Echinococcus granulosus SAM and MBT domain containing protein 0.0052 0.0559 0.0533
Onchocerca volvulus 0.0052 0.0559 0.1754
Echinococcus multilocularis thymidylate synthase 0.0228 0.3145 0.3126
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0027 0.0071
Plasmodium vivax bifunctional dihydrofolate reductase-thymidylate synthase, putative 0.0465 0.6596 1
Schistosoma mansoni hypothetical protein 0.0317 0.4438 0.4426
Schistosoma mansoni hypothetical protein 0.007 0.0831 0.0811
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0027 0.0071
Trichomonas vaginalis conserved hypothetical protein 0.0073 0.0869 0.3328
Loa Loa (eye worm) hypothetical protein 0.0169 0.2283 0.6359
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.121 0.4647
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.0871 0.1309
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0027 0.0206 0.0179
Trypanosoma brucei glucose transporter, putative 0.0033 0.0294 0.0432
Mycobacterium ulcerans esterase/lipase LipP 0.0073 0.0871 0.2613
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0033 0.0292 0.0403
Trypanosoma brucei glucose transporter, putative 0.0033 0.0294 0.0432
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0038 0.0356 0.0527
Schistosoma mansoni hypothetical protein 0.0027 0.0206 0.0184
Plasmodium falciparum ataxin-2 like protein, putative 0.0045 0.0458 0.0655
Trichomonas vaginalis glucose transporter, putative 0.0015 0.0027 0.0071
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0073 0.0871 0.1282
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0062 0.0713 0.1069
Schistosoma mansoni glucose transport protein 0.0108 0.1378 0.1358
Mycobacterium ulcerans hypothetical protein 0.0073 0.0871 0.2613
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.035 0.0518
Echinococcus granulosus General substrate transporter 0.0092 0.1157 0.1132
Brugia malayi Inositol-1 0.0036 0.0337 0.0932
Schistosoma mansoni hypothetical protein 0.0029 0.023 0.0209
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0125 0.1626 0.4526
Leishmania major dihydrofolate reductase-thymidylate synthase 0.0465 0.6596 1
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0033 0.0292 0.0265
Entamoeba histolytica acetyltransferase, GNAT family 0.0042 0.0423 0.1821
Loa Loa (eye worm) thymidylate synthase 0.0228 0.3145 0.876
Trichomonas vaginalis glucosylceramidase, putative 0.0125 0.1636 0.6292
Giardia lamblia Lysyl-tRNA synthetase 0.0024 0.0157 0.1097
Schistosoma mansoni patched 1 0.0073 0.0869 0.0849
Echinococcus granulosus cpg binding protein 0.0024 0.0164 0.0137
Brugia malayi Glycosyl hydrolases family 31 protein 0.0014 0.0009 0.0018
Loa Loa (eye worm) ICD-1 protein 0.0096 0.1216 0.3387
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0169 0.2283 1
Schistosoma mansoni protein kinase 0.0033 0.0292 0.0271
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0033 0.0292 0.0265
Trypanosoma cruzi PAB1-binding protein , putative 0.0045 0.0458 0.0681
Toxoplasma gondii lysine-tRNA ligase 0.0024 0.0157 0.0198
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0027 0.0071
Loa Loa (eye worm) hypothetical protein 0.0015 0.0027 0.0076
Plasmodium falciparum calcium-dependent protein kinase 2 0.0033 0.0292 0.0403
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0032 0.0278 0.1183
Schistosoma mansoni myelin transcription factor 1 myt1 0.0059 0.0663 0.0642
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0015 0.0027 0.0028
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0027 0.0071
Schistosoma mansoni jumonji/arid domain-containing protein 0.0038 0.0367 0.0346
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0027 0.0071
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0027 0.0071
Plasmodium vivax proline--tRNA ligase, putative 0.0038 0.0356 0.05
Trypanosoma brucei transcription factor BTF3, putative 0.0096 0.1216 0.1832
Loa Loa (eye worm) beta-lactamase 0.0073 0.0871 0.2427
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0037 0.035 0.0975
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0172 0.2321 0.2304
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0033 0.0292 0.043
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0033 0.0292 0.0814
Trypanosoma cruzi transcription factor btf3, putative 0.0096 0.1216 0.1832
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0049 0.0516 0.1962
Schistosoma mansoni zinc finger protein 0.0026 0.0189 0.0167
Echinococcus multilocularis calcium dependent protein kinase 0.0031 0.0258 0.0231
Loa Loa (eye worm) hypothetical protein 0.0019 0.0082 0.0229
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0027 0.0071
Onchocerca volvulus Alhambra homolog 0.0029 0.023 0.0707
Trichomonas vaginalis CAMK family protein kinase 0.0033 0.0292 0.1095
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0013 0.0003 0.0007
Loa Loa (eye worm) hypothetical protein 0.0032 0.0278 0.0774
Loa Loa (eye worm) CXXC zinc finger family protein 0.0021 0.0117 0.0325
Trypanosoma brucei glucose transporter, putative 0.0033 0.0294 0.0432
Brugia malayi beta-lactamase family protein 0.0073 0.0871 0.2422
Plasmodium falciparum lysine--tRNA ligase 0.0024 0.0157 0.0198
Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase 0.0465 0.6596 1
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0027 0.0071
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0337 0.1268
Onchocerca volvulus 0.0021 0.0117 0.0343
Trichomonas vaginalis maltase-glucoamylase, putative 0.0037 0.035 0.1319
Trichomonas vaginalis glucosylceramidase, putative 0.0191 0.2594 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.069 0.205
Onchocerca volvulus Glucosylceramidase homolog 0.0125 0.1636 0.5187
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0174 0.235 0.3535
Echinococcus granulosus lysyl tRNA synthetase 0.0024 0.0157 0.013
Trypanosoma cruzi glucose transporter, putative 0.0015 0.0027 0.0028
Brugia malayi hypothetical protein 0.0045 0.0458 0.1268
Schistosoma mansoni kinase 0.005 0.0535 0.0514
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0032 0.0278 0.0251
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0024 0.0157 0.0402
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0073 0.0871 0.2422
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0089 0.0062
Brugia malayi latrophilin 2 splice variant baaae 0.0059 0.067 0.186
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0125 0.1626 0.1608
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0062 0.0713 0.0687
Echinococcus multilocularis Niemann Pick C1 protein 0.0242 0.3345 0.3327
Trypanosoma brucei dihydrofolate reductase-thymidylate synthase 0.0465 0.6596 1
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.006 0.069 0.1033
Echinococcus granulosus GPCR family 2 0.0027 0.0206 0.0179
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0086 0.107 0.2974
Loa Loa (eye worm) hypothetical protein 0.0015 0.0027 0.0076
Schistosoma mansoni inositol monophosphatase 0.0036 0.0337 0.0315
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0159 0.213 0.2113
Echinococcus granulosus expressed conserved protein 0.0159 0.2133 0.2111
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0027 0.0071
Onchocerca volvulus 0.0015 0.0027 0.0059
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0108 0.1378 0.1354
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0032 0.0278 0.0256
Onchocerca volvulus 0.0228 0.3145 1
Schistosoma mansoni transcription factor btf3 0.0096 0.1216 0.1196
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0159 0.213 0.2109
Loa Loa (eye worm) transcription factor SMAD2 0.0088 0.1095 0.3051
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.121 0.4647
Trichomonas vaginalis conserved hypothetical protein 0.0096 0.1216 0.4669
Schistosoma mansoni sugar transporter 0.0015 0.0027 0.0005
Trypanosoma cruzi hexose transporter, putative 0.0033 0.0294 0.0432
Schistosoma mansoni hypothetical protein 0.0017 0.0048 0.0026
Plasmodium falciparum phd finger protein, putative 0.0029 0.023 0.0309
Plasmodium falciparum calcium-dependent protein kinase 1 0.0033 0.0292 0.0403
Trypanosoma cruzi ISWI complex protein 0.0017 0.0048 0.0059
Onchocerca volvulus 0.0015 0.0027 0.0059
Brugia malayi hypothetical protein 0.0015 0.0027 0.0069
Plasmodium vivax lysine--tRNA ligase, putative 0.0024 0.0157 0.0198
Brugia malayi thymidylate synthase 0.0228 0.3145 0.8759
Brugia malayi Bromodomain containing protein 0.0045 0.0467 0.1294
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.069 0.205
Echinococcus multilocularis protein dispatched 1 0.0083 0.1019 0.0995
Echinococcus granulosus calcium dependent protein kinase 0.0031 0.0258 0.0231
Entamoeba histolytica transcription factor BTF3, putative 0.0096 0.1216 0.5308
Trichomonas vaginalis glucosylceramidase, putative 0.0191 0.2594 1
Schistosoma mansoni sugar transporter 0.0015 0.0027 0.0005
Schistosoma mansoni alpha glucosidase 0.0037 0.035 0.0329
Giardia lamblia Histone acetyltransferase GCN5 0.0042 0.0423 0.3344
Echinococcus granulosus lysosomal alpha glucosidase 0.0168 0.2256 0.2234
Plasmodium vivax calcium-dependent protein kinase, putative 0.0033 0.0292 0.0403
Trichomonas vaginalis glucosylceramidase, putative 0.0125 0.1636 0.6292
Schistosoma mansoni hypothetical protein 0.0059 0.067 0.0649
Loa Loa (eye worm) hypothetical protein 0.0032 0.0278 0.0774
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0033 0.0292 0.0265
Trichomonas vaginalis sucrase-isomaltase, putative 0.0037 0.035 0.1319
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0032 0.0278 0.055
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0037 0.035 0.0491
Schistosoma mansoni protein kinase 0.0033 0.0292 0.0271
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0027 0.0071
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0095 0.1195 0.1171
Mycobacterium tuberculosis Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) 0.0236 0.3258 0.4908
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0089 0.0122
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0027 0.0071
Trichomonas vaginalis glucosylceramidase, putative 0.0132 0.1734 0.6673
Plasmodium falciparum protein kinase 7 0.0304 0.425 0.6428
Schistosoma mansoni hypothetical protein 0.0302 0.4221 0.4209
Echinococcus multilocularis Niemann Pick C1 protein 0.0169 0.2283 0.2261
Onchocerca volvulus 0.0015 0.0027 0.0059
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0033 0.0292 0.0403
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0125 0.1626 0.453
Plasmodium falciparum proline--tRNA ligase 0.0038 0.0356 0.05
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0027 0.0071
Brugia malayi Cam kinase protein 1 0.0033 0.0292 0.0807
Trypanosoma brucei THT1 - hexose transporter, putative 0.0033 0.0294 0.0432
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.002 0.0099 0.0071
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0062 0.0713 0.1069
Echinococcus multilocularis GPCR, family 2 0.0027 0.0206 0.0179
Toxoplasma gondii facilitative glucose transporter GT1 0.0108 0.1378 0.2055
Trypanosoma cruzi polo-like protein kinase, putative 0.0096 0.121 0.1824
Loa Loa (eye worm) hypothetical protein 0.0051 0.0553 0.154
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0027 0.0206 0.0179
Onchocerca volvulus 0.0015 0.0027 0.0059
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0089 0.0062
Mycobacterium ulcerans beta-lactamase 0.0073 0.0871 0.2613
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.069 0.205
Brugia malayi Major Facilitator Superfamily protein 0.0015 0.0027 0.0069
Schistosoma mansoni glucose transport protein 0.0108 0.1378 0.1358
Echinococcus granulosus histone acetyltransferase MYST2 0.0059 0.0663 0.0637
Plasmodium vivax basic transcription factor 3b, putative 0.0096 0.1216 0.1809
Echinococcus multilocularis lysine specific demethylase 5A 0.0035 0.032 0.0293
Echinococcus multilocularis lysosomal alpha glucosidase 0.0168 0.2256 0.2234
Leishmania major protein kinase, putative 0.0033 0.0292 0.043
Plasmodium vivax ataxin-2 like protein, putative 0.0045 0.0458 0.0655
Loa Loa (eye worm) hypothetical protein 0.0076 0.0922 0.2569
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0337 0.0498
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0108 0.1378 0.1354
Mycobacterium tuberculosis Conserved protein 0.0073 0.0871 0.1282
Brugia malayi Latrophilin receptor protein 2 0.0027 0.0206 0.0567
Plasmodium falciparum ataxin-2 like protein, putative 0.0045 0.0458 0.0655
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0089 0.0094
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0033 0.0292 0.0265
Trichomonas vaginalis glucosylceramidase, putative 0.0191 0.2594 1
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0018 0.0076 0.0048
Brugia malayi intermediate filament protein 0.0025 0.0173 0.0474
Brugia malayi Sugar transporter family protein 0.0015 0.0027 0.0069
Mycobacterium tuberculosis Probable esterase LipL 0.0073 0.0871 0.1282
Schistosoma mansoni ap endonuclease 0.0019 0.0089 0.0067
Schistosoma mansoni lamin 0.0025 0.0173 0.0151
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0089 0.0242
Echinococcus multilocularis peregrin 0.0035 0.0324 0.0297
Trypanosoma brucei ISWI complex protein 0.0017 0.0048 0.0059
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0027 0.0071
Echinococcus multilocularis zinc finger protein 0.0026 0.0189 0.0162
Loa Loa (eye worm) hypothetical protein 0.0015 0.0027 0.0076
Onchocerca volvulus 0.0015 0.0027 0.0059
Brugia malayi hypothetical protein 0.0015 0.0027 0.0069
Loa Loa (eye worm) hypothetical protein 0.0015 0.0027 0.0076
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0062 0.0713 0.1069
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0027 0.0071
Loa Loa (eye worm) hypothetical protein 0.0015 0.0027 0.0076
Onchocerca volvulus 0.0015 0.0027 0.0059
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0021 0.0114 0.0406
Loa Loa (eye worm) hypothetical protein 0.0015 0.0027 0.0076
Onchocerca volvulus 0.0015 0.0027 0.0059
Schistosoma mansoni inositol monophosphatase 0.0036 0.0337 0.0315
Plasmodium falciparum calcium-dependent protein kinase 4 0.0033 0.0292 0.0403
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0037 0.035 0.15
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0032 0.0281 0.0386
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.006 0.069 0.0664
Loa Loa (eye worm) hypothetical protein 0.0048 0.0505 0.1407
Trichomonas vaginalis glucosylceramidase, putative 0.0125 0.1636 0.6292
Onchocerca volvulus 0.0015 0.0027 0.0059
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0089 0.0311
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.002 0.0099 0.0071
Brugia malayi Dihydrofolate reductase 0.0236 0.3258 0.9074
Onchocerca volvulus Huntingtin homolog 0.0132 0.1739 0.5518
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.035 0.1319
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0027 0.0071
Trypanosoma cruzi transcription factor btf3, putative 0.0096 0.1216 0.1832
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0096 0.121 0.1824
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0027 0.0071
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0033 0.0292 0.0807
Schistosoma mansoni methyl-cpg binding protein mbd 0.0018 0.0076 0.0054
Brugia malayi PHD-finger family protein 0.0029 0.023 0.0635
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0073 0.0871 0.2613
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.006 0.069 0.1006
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0207 0.2829 0.2809
Giardia lamblia PHD finger protein 15 0.0029 0.023 0.1717
Onchocerca volvulus 0.0015 0.0027 0.0059
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0032 0.0278 0.104
Loa Loa (eye worm) inositol-1 0.0036 0.0337 0.0938
Onchocerca volvulus 0.0025 0.0173 0.0522
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0032 0.0278 0.0767
Brugia malayi Major Facilitator Superfamily protein 0.0015 0.0027 0.0069
Schistosoma mansoni lysyl-tRNA synthetase 0.0024 0.0157 0.0135
Plasmodium falciparum calcium-dependent protein kinase 5 0.0033 0.0292 0.0403
Echinococcus granulosus histone acetyltransferase KAT2B 0.0049 0.0516 0.049
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0294 0.1102
Loa Loa (eye worm) hypothetical protein 0.0059 0.067 0.1866
Echinococcus granulosus intermediate filament protein 0.0025 0.0173 0.0146
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.0871 0.1309
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.023 0.0642
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0086 0.107 0.2979
Loa Loa (eye worm) hypothetical protein 0.0086 0.107 0.2979
Trypanosoma cruzi hexose transporter, putative 0.0033 0.0294 0.0432
Trichomonas vaginalis glucose transporter, putative 0.0033 0.0294 0.1102
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0027 0.0071
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.035 0.1319
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0062 0.0713 0.1044
Plasmodium vivax hexose transporter 0.0108 0.1378 0.2055
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0024 0.0157 0.0225
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.006 0.069 0.0664
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0015 0.0027 0.0005
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0062 0.0713 0.1069
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0073 0.0871 0.0851
Trypanosoma brucei THT1 - hexose transporter, putative 0.0033 0.0294 0.0432
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.069 0.0669
Leishmania major lysyl-tRNA synthetase, putative 0.0024 0.0157 0.0225
Loa Loa (eye worm) hypothetical protein 0.0132 0.1739 0.4845
Schistosoma mansoni dihydrofolate reductase 0.0236 0.3258 0.3243
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0027 0.0071
Trichomonas vaginalis glucosylceramidase, putative 0.0125 0.1636 0.6292
Echinococcus multilocularis lysosomal alpha glucosidase 0.0168 0.2256 0.2234
Brugia malayi acetyltransferase, GNAT family protein 0.0159 0.213 0.5931
Brugia malayi Glycosyl hydrolases family 31 protein 0.0037 0.035 0.0968
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0073 0.0871 0.0851
Loa Loa (eye worm) hypothetical protein 0.0015 0.0027 0.0076
Brugia malayi Sugar transporter family protein 0.0015 0.0027 0.0069
Schistosoma mansoni glucose transporter 0.0015 0.0027 0.0005
Echinococcus multilocularis PHD finger protein rhinoceros 0.0029 0.023 0.0204
Brugia malayi Bromodomain containing protein 0.0086 0.1063 0.2957
Plasmodium falciparum protein kinase 6 0.0457 0.6479 0.9822
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0125 0.1626 0.1603
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0466 0.6609 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0027 0.0076
Brugia malayi hypothetical protein 0.0029 0.0227 0.0625
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0073 0.0871 0.1282
Trichomonas vaginalis esterase, putative 0.0073 0.0871 0.3336
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0089 0.0094
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.121 0.4647
Loa Loa (eye worm) hypothetical protein 0.0059 0.0663 0.1847
Schistosoma mansoni bromodomain containing protein 0.0073 0.0878 0.0858
Loa Loa (eye worm) hypothetical protein 0.0025 0.0166 0.0462
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0026 0.018 0.0158
Loa Loa (eye worm) hypothetical protein 0.005 0.0533 0.1486
Leishmania major glucose transporter, lmgt3 0.0033 0.0294 0.0432
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0033 0.0292 0.0403
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0294 0.1102
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0337 0.0498
Echinococcus granulosus dihydrofolate reductase 0.0236 0.3258 0.3239
Onchocerca volvulus Putative transporter 0.0015 0.0027 0.0059
Loa Loa (eye worm) hypothetical protein 0.0029 0.023 0.0642
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0049 0.0516 0.0744
Trichomonas vaginalis glucosylceramidase, putative 0.0125 0.1636 0.6292
Brugia malayi beta-NAC-like protein 0.0096 0.1216 0.3382
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0027 0.0071
Mycobacterium ulcerans lipase LipD 0.0073 0.0871 0.2613
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.035 0.1319
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0062 0.0713 0.1044
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0027 0.0071
Brugia malayi serine/threonine-protein kinase plk-2 0.0096 0.121 0.3366
Echinococcus multilocularis expressed conserved protein 0.0159 0.2133 0.2111
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0033 0.0292 0.0265
Loa Loa (eye worm) hypothetical protein 0.0015 0.0027 0.0076
Plasmodium falciparum histone acetyltransferase GCN5 0.0042 0.0423 0.0602
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.035 0.1319
Schistosoma mansoni zinc finger protein 0.0017 0.0048 0.0026
Leishmania major hypothetical protein, conserved 0.0017 0.0048 0.0059
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0062 0.0713 0.0687
Mycobacterium leprae Probable lipase LipE 0.0073 0.0871 0.2432
Plasmodium falciparum hexose transporter 0.0108 0.1378 0.2055
Entamoeba histolytica serine/threonine protein kinase, putative 0.0096 0.121 0.5283
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0027 0.0071
Echinococcus multilocularis SAM and MBT domain containing protein 0.0052 0.0559 0.0533
Echinococcus granulosus PHD finger protein rhinoceros 0.0029 0.023 0.0204
Brugia malayi hypothetical protein 0.0015 0.0027 0.0069
Schistosoma mansoni methyl-cpg binding protein mbd 0.0018 0.0076 0.0054
Echinococcus multilocularis protein patched 0.0073 0.0869 0.0844
Brugia malayi Zinc finger, C2H2 type family protein 0.0259 0.359 1
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0027 0.0206 0.0567
Echinococcus granulosus neutral alpha glucosidase AB 0.0037 0.035 0.0323
Trichomonas vaginalis glucosylceramidase, putative 0.0132 0.1734 0.6673
Brugia malayi hypothetical protein 0.0064 0.0736 0.2044
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.023 0.0309
Schistosoma mansoni cpg binding protein 0.0024 0.0164 0.0143
Mycobacterium tuberculosis Conserved protein 0.0073 0.0871 0.1282
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0027 0.0071
Leishmania major alpha glucosidase II subunit, putative 0.0037 0.035 0.0518
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0032 0.0278 0.0256
Trichomonas vaginalis glucose transporter, putative 0.0033 0.0294 0.1102
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0059 0.0663 0.1841
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.0337 0.1442
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0337 0.1268
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0125 0.1626 0.1608
Loa Loa (eye worm) sugar transporter 0.0015 0.0027 0.0076
Trichomonas vaginalis myo-inositol transporter, putative 0.0015 0.0027 0.0071
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0073 0.0869 0.2421
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0089 0.0191
Echinococcus granulosus fetal alzheimer antigen falz 0.0026 0.018 0.0153
Trichomonas vaginalis conserved hypothetical protein 0.0108 0.1378 0.5294
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0059 0.0663 0.0637
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0024 0.0157 0.0225
Trypanosoma brucei glucose transporter, putative 0.0033 0.0294 0.0432
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0125 0.1626 0.1603
Schistosoma mansoni bifunctional dihydrofolate reductase-thymidylate synthase 0.0228 0.3145 0.3129
Brugia malayi jmjC domain containing protein 0.0038 0.0367 0.1017
Mycobacterium ulcerans dihydrofolate reductase DfrA 0.0236 0.3258 1
Brugia malayi Niemann-Pick C1 protein precursor 0.0169 0.2283 0.6356
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0019 0.0082 0.006
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0027 0.0071
Brugia malayi Sugar transporter family protein 0.0108 0.1378 0.3833
Brugia malayi major facilitator superfamily protein 0.0015 0.0027 0.0069
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0038 0.0356 0.05
Trypanosoma brucei glucose transporter, putative 0.0033 0.0294 0.0432
Echinococcus multilocularis dihydrofolate reductase 0.0236 0.3258 0.3239
Brugia malayi hypothetical protein 0.0132 0.1739 0.4841
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0045 0.0464 0.0443
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0027 0.0071
Loa Loa (eye worm) hypothetical protein 0.0033 0.0292 0.0814
Loa Loa (eye worm) PHD-finger family protein 0.0022 0.0132 0.0368
Echinococcus multilocularis polycomb protein SCMH1 0.0052 0.0559 0.0533
Echinococcus multilocularis transcription factor btf3 0.0096 0.1216 0.1192
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0089 0.0249
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0517 0.1964
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0062 0.0713 0.0687
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0024 0.0157 0.0402
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0038 0.0356 0.0527
Mycobacterium tuberculosis Probable lipase LipE 0.0073 0.0871 0.1282
Mycobacterium tuberculosis Probable lipase LipD 0.0073 0.0871 0.1282
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0294 0.1102
Brugia malayi beta-lactamase family protein 0.0073 0.0871 0.2422
Trichomonas vaginalis conserved hypothetical protein 0.0096 0.1216 0.4669
Echinococcus multilocularis musashi 0.0025 0.0173 0.0146
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.007 0.0822 0.0797
Trichomonas vaginalis glucosylceramidase, putative 0.0125 0.1636 0.6292
Onchocerca volvulus 0.0025 0.0173 0.0522
Echinococcus granulosus Niemann Pick C1 protein 0.0169 0.2283 0.2261
Echinococcus granulosus lamin 0.0025 0.0173 0.0146
Mycobacterium tuberculosis Probable hydrolase 0.0073 0.0871 0.1282
Loa Loa (eye worm) zinc finger protein 0.0259 0.359 1
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.121 0.4647
Loa Loa (eye worm) jmjC domain-containing protein 0.006 0.0682 0.19
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0027 0.0071
Loa Loa (eye worm) hypothetical protein 0.0073 0.0869 0.2421
Echinococcus multilocularis lamin 0.0025 0.0173 0.0146
Toxoplasma gondii histone lysine methyltransferase SET1 0.0047 0.0487 0.07
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0108 0.1378 0.1354
Entamoeba histolytica protein kinase, putative 0.0033 0.0292 0.1245
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0337 0.0498
Leishmania major myo-inositol/proton symporter (MIT) 0.0015 0.0027 0.0028
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0108 0.1378 0.1354
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.0337 0.031
Echinococcus granulosus jumonji domain containing protein 0.004 0.0397 0.037
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0089 0.0523
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.0337 0.031
Onchocerca volvulus Serine\/threonine kinase homolog 0.0096 0.121 0.3831
Loa Loa (eye worm) hypothetical protein 0.0089 0.1108 0.3087
Toxoplasma gondii exonuclease III APE 0.0019 0.0089 0.0094
Entamoeba histolytica protein kinase, putative 0.0033 0.0292 0.1245
Brugia malayi F/Y-rich N-terminus family protein 0.0018 0.007 0.0188
Brugia malayi CXXC zinc finger family protein 0.0021 0.0117 0.0317
Brugia malayi mbt repeat family protein 0.0052 0.0559 0.1551
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0033 0.0292 0.0265
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase 0.0465 0.6596 1
Schistosoma mansoni sex comb on midleg homolog 0.0052 0.0559 0.0538
Brugia malayi hypothetical protein 0.0109 0.1395 0.388
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.035 0.1319
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0033 0.0292 0.0403
Trypanosoma cruzi hexose transporter, putative 0.0018 0.0073 0.0097
Brugia malayi MH2 domain containing protein 0.0088 0.1095 0.3046
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0025 0.0173 0.0481
Echinococcus multilocularis dnaJ subfamily B 0.0302 0.4221 0.4206
Loa Loa (eye worm) hypothetical protein 0.0015 0.0027 0.0076
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.0871 0.3336
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0027 0.0071
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0294 0.1102
Loa Loa (eye worm) bromodomain containing protein 0.0023 0.0141 0.0393
Echinococcus granulosus peregrin 0.0035 0.0324 0.0297
Loa Loa (eye worm) hypothetical protein 0.0015 0.0027 0.0076
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0027 0.0071
Echinococcus multilocularis sterol regulatory element binding protein 0.0073 0.0869 0.0844
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0599 0.8559 0.8555
Echinococcus granulosus beta LACTamase domain containing family member 0.0073 0.0871 0.0846
Schistosoma mansoni serine/threonine protein kinase 0.0033 0.0292 0.0271
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0108 0.1378 0.1354
Loa Loa (eye worm) hypothetical protein 0.0073 0.0871 0.2427
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0027 0.0071
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0027 0.0071
Entamoeba histolytica hypothetical protein 0.0096 0.1216 0.5308
Echinococcus multilocularis isocitrate dehydrogenase 0.0062 0.0713 0.0687
Trichomonas vaginalis penicillin-binding protein, putative 0.0073 0.0871 0.3336
Loa Loa (eye worm) hypothetical protein 0.0073 0.0871 0.2427
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0027 0.0071
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0027 0.0071
Loa Loa (eye worm) hypothetical protein 0.0027 0.0206 0.0574
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0062 0.0713 0.0692
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0033 0.0292 0.0265
Trypanosoma brucei glucose transporter, putative 0.0033 0.0294 0.0432
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0039 0.0373 0.0347
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.0337 0.0471
Schistosoma mansoni jumonji domain containing protein 0.0076 0.091 0.089
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0064 0.0736 0.071
Loa Loa (eye worm) major facilitator superfamily transporter 0.0015 0.0027 0.0076
Onchocerca volvulus 0.0015 0.0027 0.0059
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0039 0.0373 0.0347
Echinococcus multilocularis beta LACTamase domain containing family member 0.0073 0.0871 0.0846
Loa Loa (eye worm) hypothetical protein 0.0073 0.0871 0.2427
Mycobacterium leprae DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) 0.0236 0.3258 1
Echinococcus granulosus Protein patched homolog 1 0.0073 0.0869 0.0844
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0073 0.0871 0.1282
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0024 0.0157 0.0168
Onchocerca volvulus 0.0015 0.0027 0.0059
Loa Loa (eye worm) hypothetical protein 0.0015 0.0027 0.0076
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0096 0.121 0.1186
Toxoplasma gondii NAC domain-containing protein 0.0096 0.1216 0.1809
Entamoeba histolytica hypothetical protein 0.0064 0.0736 0.3197
Brugia malayi isocitrate dehydrogenase 0.0062 0.0713 0.198
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0033 0.0292 0.0265
Echinococcus granulosus sterol regulatory element binding protein 0.0073 0.0869 0.0844
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0027 0.0071
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0191 0.2594 0.7224
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0064 0.0736 0.071
Toxoplasma gondii aldehyde dehydrogenase 0.006 0.069 0.1008
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0062 0.0713 0.0687
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.035 0.0518
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0033 0.0292 0.0814
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0108 0.1378 0.1354
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0038 0.0356 0.0527
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0027 0.0071
Brugia malayi jmjC domain containing protein 0.0095 0.1195 0.3324
Schistosoma mansoni sugar transporter 0.0015 0.0027 0.0005
Trypanosoma cruzi hexose transporter, putative 0.0015 0.0027 0.0028
Echinococcus granulosus zinc finger protein 0.0026 0.0189 0.0162
Loa Loa (eye worm) hypothetical protein 0.0025 0.0173 0.0481
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0191 0.2594 0.7226
Toxoplasma gondii LsmAD domain-containing protein 0.0045 0.0458 0.0655
Onchocerca volvulus 0.0015 0.0027 0.0059
Trichomonas vaginalis glucosylceramidase, putative 0.0191 0.2594 1
Toxoplasma gondii bifunctional dihydrofolate reductase-thymidylate synthase 0.0465 0.6596 1
Trypanosoma cruzi hexose transporter, putative 0.0033 0.0294 0.0432
Loa Loa (eye worm) hypothetical protein 0.0041 0.0412 0.1147
Trichomonas vaginalis sugar transport protein, putative 0.0015 0.0027 0.0071
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0517 0.1964
Mycobacterium ulcerans thymidylate synthase 0.0228 0.3145 0.965
Echinococcus multilocularis zinc finger transcription factor gli2 0.0259 0.359 0.3572
Trypanosoma cruzi ISWI complex protein 0.0017 0.0048 0.0059
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0125 0.1626 0.1603
Onchocerca volvulus 0.0097 0.1223 0.3872
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0027 0.0071
Entamoeba histolytica hypothetical protein 0.0064 0.0736 0.3197
Trypanosoma brucei sugar transporter, putative 0.0015 0.0027 0.0028
Trichomonas vaginalis bromodomain-containing protein, putative 0.0049 0.0516 0.1962
Schistosoma mansoni lysyl-tRNA synthetase 0.0024 0.0157 0.0135
Mycobacterium tuberculosis Hypothetical protein 0.0109 0.1395 0.2077
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0027 0.0071
Brugia malayi PHD-finger family protein 0.0032 0.0273 0.0754
Schistosoma mansoni sex comb on midleg homolog 0.0052 0.0559 0.0538
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.002 0.0104 0.0117
Loa Loa (eye worm) sugar transporter 0.0108 0.1378 0.3837
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0033 0.0292 0.0403
Echinococcus multilocularis neutral alpha glucosidase AB 0.0037 0.035 0.0323
Brugia malayi mbt repeat family protein 0.0052 0.0559 0.1551
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0052 0.0559 0.1754
Loa Loa (eye worm) hypothetical protein 0.0026 0.0189 0.0528
Echinococcus granulosus lysine specific demethylase 5A 0.0038 0.0367 0.0341
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0089 0.5
Trichomonas vaginalis glucosylceramidase, putative 0.0191 0.2594 1
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0032 0.0278 0.0251
Schistosoma mansoni sugar transporter 0.0015 0.0027 0.0005
Schistosoma mansoni alpha-glucosidase 0.0144 0.1915 0.1897
Brugia malayi Isocitrate dehydrogenase 0.0062 0.0713 0.198
Schistosoma mansoni lamin 0.0025 0.0173 0.0151
Schistosoma mansoni protein kinase 0.0033 0.0292 0.0271
Schistosoma mansoni serine/threonine protein kinase 0.0096 0.121 0.1191
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0089 0.0353
Plasmodium falciparum mitogen-activated protein kinase 2 0.0174 0.235 0.3535
Trypanosoma cruzi hexose transporter 0.0033 0.0294 0.0432
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase, putative 0.0109 0.1395 0.2104
Trypanosoma cruzi polo-like protein kinase, putative 0.0096 0.121 0.1824
Mycobacterium leprae PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) 0.0228 0.3145 0.9642
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0089 0.0122
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0027 0.0206 0.0179
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0029 0.023 0.0209
Leishmania major hypothetical protein, conserved 0.0073 0.0871 0.1309
Brugia malayi Glycosyl hydrolases family 31 protein 0.0168 0.2256 0.6281
Trypanosoma brucei hypothetical protein, conserved 0.0073 0.0871 0.1309
Schistosoma mansoni hypothetical protein 0.0027 0.0206 0.0184
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0089 0.0311
Schistosoma mansoni hypothetical protein 0.0027 0.0206 0.0184
Echinococcus multilocularis lamin dm0 0.0025 0.0173 0.0146
Schistosoma mansoni cpg binding protein 0.0024 0.0164 0.0143
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.121 0.4647
Schistosoma mansoni transcription factor LCR-F1 0.0064 0.0736 0.0715
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.0337 0.1268
Mycobacterium tuberculosis Probable thymidylate synthase ThyA (ts) (TSASE) 0.0228 0.3145 0.4736
Loa Loa (eye worm) MH2 domain-containing protein 0.0088 0.1095 0.3051
Loa Loa (eye worm) hypothetical protein 0.0073 0.0871 0.2427
Trypanosoma cruzi sugar transporter, putative 0.0015 0.0027 0.0028
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0125 0.1626 0.1608
Leishmania major basic transcription factor 3a, putative 0.0096 0.1216 0.1832
Schistosoma mansoni hypothetical protein 0.0108 0.1378 0.1358
Onchocerca volvulus 0.0073 0.0871 0.275
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0073 0.0871 0.2427
Plasmodium vivax hypothetical protein, conserved 0.0029 0.023 0.0309
Trypanosoma brucei glucose transporter 2A 0.0033 0.0294 0.0432
Brugia malayi beta-lactamase 0.0073 0.0871 0.2422
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0096 0.121 0.1186
Brugia malayi Calcitonin receptor-like protein seb-1 0.0086 0.107 0.2974
Toxoplasma gondii isocitrate dehydrogenase 0.0062 0.0713 0.1044
Trypanosoma brucei PAB1-binding protein , putative 0.0045 0.0458 0.0681
Loa Loa (eye worm) isocitrate dehydrogenase 0.0062 0.0713 0.1986
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0089 0.1999
Onchocerca volvulus 0.0015 0.0027 0.0059
Echinococcus granulosus dnaJ subfamily B 0.0302 0.4221 0.4206
Entamoeba histolytica hypothetical protein 0.0024 0.0157 0.0652
Trypanosoma brucei polo-like protein kinase 0.0096 0.121 0.1824
Trichomonas vaginalis glucosylceramidase, putative 0.0125 0.1636 0.6292
Brugia malayi Major Facilitator Superfamily protein 0.0015 0.0027 0.0069
Plasmodium falciparum calcium-dependent protein kinase 3 0.0033 0.0292 0.0403
Echinococcus multilocularis cpg binding protein 0.0024 0.0164 0.0137
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0049 0.0516 0.0744
Loa Loa (eye worm) MBCTL1 0.0059 0.0663 0.1847
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0027 0.0206 0.0179
Loa Loa (eye worm) hypothetical protein 0.0015 0.0027 0.0076
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.035 0.1319
Trichomonas vaginalis conserved hypothetical protein 0.0096 0.1216 0.4669
Trypanosoma cruzi PAB1-binding protein , putative 0.0045 0.0458 0.0681
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0337 0.0498
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0033 0.0292 0.0403
Schistosoma mansoni hypothetical protein 0.007 0.0831 0.0811
Plasmodium falciparum basic transcription factor 3b, putative 0.0096 0.1216 0.1809
Loa Loa (eye worm) intermediate filament protein 0.0025 0.0173 0.0481
Toxoplasma gondii protein kinase, putative 0.0304 0.425 0.6428
Loa Loa (eye worm) mbt repeat family protein 0.0052 0.0559 0.1557
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0049 0.0516 0.0744
Loa Loa (eye worm) hypothetical protein 0.0015 0.0027 0.0076
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0108 0.1378 0.1354
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.121 0.4647
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0027 0.0071
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.007 0.0822 0.0797
Echinococcus granulosus transcription factor btf3 0.0096 0.1216 0.1192
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0052 0.0559 0.0538
Loa Loa (eye worm) hypothetical protein 0.0052 0.0559 0.1557
Leishmania major hypothetical protein, conserved 0.0045 0.0458 0.0681
Mycobacterium leprae conserved hypothetical protein 0.0073 0.0871 0.2432
Echinococcus granulosus histone acetyltransferase KAT2B 0.0152 0.2029 0.2007
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0027 0.0071
Trichomonas vaginalis glucosylceramidase, putative 0.0191 0.2594 1
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0207 0.2829 0.2809
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0125 0.1626 0.1603
Loa Loa (eye worm) hypothetical protein 0.0015 0.0027 0.0076
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0038 0.0356 0.0527
Schistosoma mansoni hypothetical protein 0.0064 0.0736 0.0715
Onchocerca volvulus 0.0073 0.0871 0.275
Mycobacterium tuberculosis Conserved protein 0.0073 0.0871 0.1282

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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