Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0054 | 0.1893 | 0.1893 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0102 | 0.7248 | 1 |
Leishmania major | protein kinase, putative,polo-like protein kinase, putative | 0.0102 | 0.7248 | 0.5 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0102 | 0.7248 | 1 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0102 | 0.7248 | 0.5 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0127 | 1 | 1 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0102 | 0.7248 | 0.5 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0102 | 0.7248 | 0.7744 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0102 | 0.7248 | 1 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0127 | 1 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0054 | 0.1893 | 0.1893 |
Trypanosoma brucei | polo-like protein kinase | 0.0102 | 0.7248 | 0.5 |
Brugia malayi | serine/threonine-protein kinase plk-2 | 0.0102 | 0.7248 | 0.7248 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.0102 | 0.7248 | 0.7248 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.1893 | 0.1893 |
Onchocerca volvulus | Serine\/threonine kinase homolog | 0.0102 | 0.7248 | 0.5 |
Schistosoma mansoni | kinase | 0.0052 | 0.1672 | 0.1787 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0102 | 0.7248 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0054 | 0.1893 | 0.1893 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0102 | 0.7248 | 1 |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.0102 | 0.7248 | 0.5 |
Giardia lamblia | Kinase, PLK | 0.0102 | 0.7248 | 0.5 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0127 | 1 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0102 | 0.7248 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0102 | 0.7248 | 1 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0121 | 0.9359 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.