Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0025 | 0.0111 | 0.0111 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0025 | 0.0111 | 0.0111 |
Onchocerca volvulus | 0.0025 | 0.0111 | 1 | |
Echinococcus multilocularis | acetylcholinesterase | 0.015 | 0.4032 | 0.4032 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0025 | 0.0111 | 0.0111 |
Loa Loa (eye worm) | hypothetical protein | 0.015 | 0.4032 | 0.4032 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0111 | 0.0111 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.015 | 0.4032 | 0.4032 |
Loa Loa (eye worm) | hypothetical protein | 0.015 | 0.4032 | 0.4032 |
Brugia malayi | Carboxylesterase family protein | 0.015 | 0.4032 | 0.4032 |
Loa Loa (eye worm) | carboxylesterase | 0.015 | 0.4032 | 0.4032 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0025 | 0.0111 | 0.5 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0025 | 0.0111 | 0.0111 |
Loa Loa (eye worm) | carboxylesterase | 0.0025 | 0.0111 | 0.0111 |
Loa Loa (eye worm) | carboxylesterase | 0.0025 | 0.0111 | 0.0111 |
Schistosoma mansoni | acetylcholinesterase | 0.0025 | 0.0111 | 0.0111 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0111 | 0.0111 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0025 | 0.0111 | 0.0111 |
Echinococcus granulosus | acetylcholinesterase | 0.015 | 0.4032 | 0.4032 |
Schistosoma mansoni | lipoxygenase | 0.0061 | 0.1235 | 0.1235 |
Brugia malayi | Carboxylesterase family protein | 0.0025 | 0.0111 | 0.0111 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0025 | 0.0111 | 0.0111 |
Echinococcus multilocularis | acetylcholinesterase | 0.015 | 0.4032 | 0.4032 |
Brugia malayi | Carboxylesterase family protein | 0.0025 | 0.0111 | 0.0111 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0111 | 0.0111 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.015 | 0.4032 | 0.4032 |
Brugia malayi | Carboxylesterase family protein | 0.0025 | 0.0111 | 0.0111 |
Onchocerca volvulus | 0.0025 | 0.0111 | 1 | |
Brugia malayi | Carboxylesterase family protein | 0.015 | 0.4032 | 0.4032 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0025 | 0.0111 | 0.0111 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0061 | 0.1235 | 0.1235 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0025 | 0.0111 | 0.0111 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0025 | 0.0111 | 0.0111 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0111 | 0.0111 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0025 | 0.0111 | 0.0111 |
Onchocerca volvulus | 0.0025 | 0.0111 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0111 | 0.0111 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0025 | 0.0111 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.0025 | 0.0111 | 0.0111 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0111 | 0.0111 |
Echinococcus granulosus | acetylcholinesterase | 0.015 | 0.4032 | 0.4032 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0025 | 0.0111 | 0.5 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0025 | 0.0111 | 0.0111 |
Echinococcus multilocularis | neuroligin | 0.0025 | 0.0111 | 0.0111 |
Onchocerca volvulus | 0.0025 | 0.0111 | 1 | |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0061 | 0.1235 | 0.1235 |
Echinococcus granulosus | neuroligin | 0.0025 | 0.0111 | 0.0111 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0025 | 0.0111 | 0.5 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0025 | 0.0111 | 0.5 |
Echinococcus multilocularis | carboxylesterase 5A | 0.015 | 0.4032 | 0.4032 |
Onchocerca volvulus | 0.0025 | 0.0111 | 1 | |
Schistosoma mansoni | gliotactin | 0.0025 | 0.0111 | 0.0111 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0025 | 0.0111 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0111 | 0.0111 |
Echinococcus granulosus | carboxylesterase 5A | 0.015 | 0.4032 | 0.4032 |
Brugia malayi | hypothetical protein | 0.0025 | 0.0111 | 0.0111 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.