Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.015 | 0.9998 | 0.9998 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.015 | 0.9998 | 0.9998 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.015 | 0.9998 | 0.9998 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.015 | 0.9998 | 0.9998 |
Schistosoma mansoni | coup transcription factor | 0.015 | 0.9998 | 0.9998 |
Loa Loa (eye worm) | hypothetical protein | 0.015 | 0.9998 | 0.9998 |
Schistosoma mansoni | nuclear hormone receptor | 0.015 | 0.9998 | 0.9998 |
Loa Loa (eye worm) | hypothetical protein | 0.015 | 0.9998 | 0.9998 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.015 | 0.9998 | 0.9998 |
Schistosoma mansoni | chromatin regulatory protein sir2 | 0.015 | 1 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.015 | 0.9998 | 0.9998 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.015 | 0.9998 | 0.9998 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.015 | 0.9998 | 0.9998 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.015 | 0.9998 | 0.9998 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.015 | 0.9998 | 0.9998 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.015 | 0.9998 | 0.9998 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.015 | 0.9998 | 0.9998 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.015 | 0.9998 | 0.9998 |
Brugia malayi | ecdysteroid receptor | 0.015 | 0.9998 | 0.9998 |
Trichomonas vaginalis | chromatin regulatory protein sir2, putative | 0.015 | 1 | 0.5 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.015 | 0.9998 | 0.9998 |
Brugia malayi | nuclear receptor NHR-88 | 0.015 | 0.9998 | 0.9998 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.015 | 0.9998 | 0.9998 |
Schistosoma mansoni | thyroid hormone receptor | 0.015 | 0.9998 | 0.9998 |
Trichomonas vaginalis | chromatin regulatory protein sir2, putative | 0.015 | 1 | 0.5 |
Schistosoma mansoni | thyroid hormone receptor | 0.015 | 0.9998 | 0.9998 |
Loa Loa (eye worm) | hypothetical protein | 0.015 | 0.9998 | 0.9998 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0079 | 0.1071 | 0.1071 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.015 | 0.9998 | 0.9998 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.015 | 0.9998 | 0.9998 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.015 | 0.9998 | 0.9998 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.015 | 0.9998 | 0.9998 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.015 | 0.9998 | 0.9998 |
Brugia malayi | hypothetical protein | 0.0079 | 0.1071 | 0.1071 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.015 | 0.9998 | 0.9998 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.015 | 0.9998 | 0.9998 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.7512 | 0.7512 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.015 | 0.9998 | 0.9998 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.015 | 0.9998 | 0.9998 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.1071 | 0.1071 |
Loa Loa (eye worm) | hypothetical protein | 0.015 | 0.9998 | 0.9998 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.015 | 0.9998 | 0.9998 |
Echinococcus multilocularis | NAD dependent deacetylase sirtuin 1 | 0.015 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.1071 | 0.1071 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.015 | 0.9998 | 0.9998 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0079 | 0.1071 | 0.1071 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.015 | 0.9998 | 1 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.015 | 0.9998 | 0.9998 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.015 | 0.9998 | 0.9998 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.015 | 0.9998 | 0.9998 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.015 | 0.9998 | 0.9998 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.015 | 0.9998 | 0.9998 |
Loa Loa (eye worm) | hypothetical protein | 0.015 | 0.9998 | 0.9998 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0079 | 0.1071 | 0.1071 |
Brugia malayi | nuclear receptor RXR | 0.0079 | 0.1071 | 0.1071 |
Echinococcus granulosus | FTZ F1 alpha | 0.015 | 0.9998 | 0.9998 |
Loa Loa (eye worm) | hypothetical protein | 0.015 | 0.9998 | 0.9998 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.1071 | 0.1071 |
Trichomonas vaginalis | chromatin regulatory protein sir2, putative | 0.015 | 1 | 0.5 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.015 | 0.9998 | 0.9998 |
Loa Loa (eye worm) | hypothetical protein | 0.015 | 0.9998 | 0.9998 |
Brugia malayi | nuclear hormone receptor | 0.015 | 0.9998 | 0.9998 |
Brugia malayi | hypothetical protein | 0.0079 | 0.1071 | 0.1071 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.015 | 0.9998 | 0.9998 |
Onchocerca volvulus | Bile acid receptor homolog | 0.015 | 0.9998 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0079 | 0.1071 | 0.1071 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.015 | 0.9998 | 0.9998 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.1071 | 0.1071 |
Loa Loa (eye worm) | steroid hormone receptor | 0.015 | 0.9998 | 0.9998 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.015 | 0.9998 | 0.9998 |
Onchocerca volvulus | 0.015 | 0.9998 | 1 | |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.015 | 0.9998 | 0.9998 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.015 | 0.9998 | 0.9998 |
Echinococcus granulosus | NAD dependent deacetylase sirtuin 1 | 0.015 | 1 | 1 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.015 | 0.9998 | 0.9998 |
Trichomonas vaginalis | chromatin regulatory protein sir2, putative | 0.015 | 1 | 0.5 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.015 | 0.9998 | 0.9998 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.015 | 0.9998 | 0.9998 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0079 | 0.1071 | 0.1071 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.015 | 0.9998 | 0.9998 |
Giardia lamblia | NAD-dependent histone deacetylase Sir2 | 0.015 | 1 | 0.5 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.015 | 0.9998 | 0.9998 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.015 | 0.9998 | 0.9998 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.015 | 0.9998 | 0.9998 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0079 | 0.1071 | 0.1071 |
Loa Loa (eye worm) | hypothetical protein | 0.015 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.015 | 0.9998 | 0.9998 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0079 | 0.1071 | 0.1071 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.015 | 0.9998 | 0.9998 |
Brugia malayi | steroid hormone receptor | 0.015 | 0.9998 | 0.9998 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.1071 | 0.1071 |
Echinococcus multilocularis | FTZ F1 alpha | 0.015 | 0.9998 | 0.9998 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.015 | 0.9998 | 0.9998 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.015 | 0.9998 | 0.9998 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.015 | 0.9998 | 0.9998 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.015 | 0.9998 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.