Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Papain family cysteine protease containing protein | 0.0169 | 0.1304 | 0.2757 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0329 | 0.4058 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0185 | 0.157 | 0.0967 |
Echinococcus multilocularis | cysteine protease | 0.0329 | 0.4058 | 0.3167 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0329 | 0.4058 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Brugia malayi | cathepsin L-like precursor | 0.022 | 0.218 | 0.5061 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0185 | 0.157 | 0.157 |
Brugia malayi | Cathepsin L-like precursor | 0.0329 | 0.4058 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0329 | 0.4058 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0329 | 0.4058 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.022 | 0.218 | 0.1008 |
Leishmania major | cathepsin L-like protease | 0.0329 | 0.4058 | 1 |
Loa Loa (eye worm) | ctsf protein | 0.0329 | 0.4058 | 1 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.022 | 0.218 | 0.5061 |
Trypanosoma brucei | polo-like protein kinase | 0.0185 | 0.157 | 0.0967 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0329 | 0.4058 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Leishmania major | cathepsin L-like protease | 0.0329 | 0.4058 | 1 |
Leishmania major | cathepsin L-like protease | 0.0329 | 0.4058 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0329 | 0.4058 | 1 |
Onchocerca volvulus | 0.0329 | 0.4058 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Plasmodium vivax | vivapain-1 | 0.0169 | 0.1304 | 0.2757 |
Leishmania major | cathepsin L-like protease | 0.0329 | 0.4058 | 1 |
Onchocerca volvulus | 0.0329 | 0.4058 | 1 | |
Onchocerca volvulus | Cathepsin L homolog | 0.0329 | 0.4058 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0169 | 0.1304 | 0.2757 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.022 | 0.218 | 0.218 |
Leishmania major | cathepsin L-like protease | 0.0329 | 0.4058 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0329 | 0.4058 | 1 |
Loa Loa (eye worm) | cysteine protease | 0.0329 | 0.4058 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0329 | 0.4058 | 1 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0329 | 0.4058 | 0.3167 |
Brugia malayi | Cathepsin L-like precursor | 0.022 | 0.218 | 0.5061 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0329 | 0.4058 | 0.3167 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0329 | 0.4058 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0329 | 0.4058 | 1 |
Schistosoma mansoni | cathepsin s | 0.0109 | 0.0255 | 0.0255 |
Onchocerca volvulus | 0.0329 | 0.4058 | 1 | |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0329 | 0.4058 | 0.4058 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.0185 | 0.157 | 0.3457 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0185 | 0.157 | 0.3457 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0329 | 0.4058 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0329 | 0.4058 | 0.3167 |
Loa Loa (eye worm) | hypothetical protein | 0.0329 | 0.4058 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Plasmodium vivax | unspecified product | 0.0169 | 0.1304 | 0.2757 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0329 | 0.4058 | 1 |
Onchocerca volvulus | Cathepsin F homolog | 0.0329 | 0.4058 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0329 | 0.4058 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.022 | 0.218 | 0.5061 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0329 | 0.4058 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0185 | 0.157 | 0.0967 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0329 | 0.4058 | 0.3167 |
Toxoplasma gondii | cathepsin CPL | 0.0329 | 0.4058 | 0.5 |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.0185 | 0.157 | 0.0967 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0169 | 0.1304 | 0.2757 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0185 | 0.157 | 0.0967 |
Onchocerca volvulus | 0.0329 | 0.4058 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0329 | 0.4058 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Giardia lamblia | Kinase, PLK | 0.0185 | 0.157 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0329 | 0.4058 | 1 |
Loa Loa (eye worm) | fibroinase | 0.0329 | 0.4058 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0185 | 0.157 | 0.0967 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0185 | 0.157 | 0.0967 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0169 | 0.1304 | 0.2757 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0329 | 0.4058 | 1 |
Onchocerca volvulus | 0.0329 | 0.4058 | 1 | |
Brugia malayi | Cathepsin L-like precursor | 0.0329 | 0.4058 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.022 | 0.218 | 0.5061 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0329 | 0.4058 | 0.3167 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0169 | 0.1304 | 0.1304 |
Brugia malayi | Cathepsin L-like precursor | 0.0329 | 0.4058 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0329 | 0.4058 | 1 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0329 | 0.4058 | 0.3167 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.0185 | 0.157 | 0.0306 |
Plasmodium vivax | vivapain-2 | 0.0329 | 0.4058 | 1 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0185 | 0.157 | 0.3457 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0329 | 0.4058 | 1 |
Onchocerca volvulus | 0.022 | 0.218 | 0.2452 | |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.0185 | 0.157 | 0.0306 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0329 | 0.4058 | 1 |
Onchocerca volvulus | 0.0329 | 0.4058 | 1 | |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.0169 | 0.1304 | 0.2757 |
Leishmania major | cathepsin L-like protease | 0.0329 | 0.4058 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0329 | 0.4058 | 0.3167 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0329 | 0.4058 | 1 |
Plasmodium vivax | vivapain-2 | 0.0329 | 0.4058 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0329 | 0.4058 | 0.3167 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.022 | 0.218 | 0.3182 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Leishmania major | cathepsin L-like protease | 0.0329 | 0.4058 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.022 | 0.218 | 0.3182 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0329 | 0.4058 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0329 | 0.4058 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0329 | 0.4058 | 1 |
Trypanosoma cruzi | cysteine protease, putative | 0.0169 | 0.1304 | 0.2757 |
Entamoeba histolytica | cysteine protease, putative | 0.0329 | 0.4058 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.022 | 0.218 | 0.3182 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.022 | 0.218 | 0.5061 |
Loa Loa (eye worm) | hypothetical protein | 0.022 | 0.218 | 0.5061 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0185 | 0.157 | 0.0967 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0329 | 0.4058 | 0.4058 |
Plasmodium vivax | vivapain-3 | 0.0169 | 0.1304 | 0.2757 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0169 | 0.1304 | 0.2757 |
Brugia malayi | serine/threonine-protein kinase plk-2 | 0.0185 | 0.157 | 0.3457 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Onchocerca volvulus | 0.0329 | 0.4058 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.022 | 0.218 | 0.5061 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0329 | 0.4058 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0329 | 0.4058 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0169 | 0.1304 | 0.1304 |
Leishmania major | cathepsin L-like protease | 0.0329 | 0.4058 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0329 | 0.4058 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0169 | 0.1304 | 0.1304 |
Leishmania major | cysteine peptidase A (CPA) | 0.0329 | 0.4058 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0185 | 0.157 | 0.0967 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0329 | 0.4058 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.