Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0102 | 0.0218 |
Mycobacterium tuberculosis | Possible zinc-containing alcohol dehydrogenase NAD dependent AdhB | 0.0132 | 0.402 | 0.4346 |
Echinococcus multilocularis | lysine specific histone demethylase 1A | 0.0021 | 0.0102 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0102 | 0.0218 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0102 | 0.0218 |
Schistosoma mansoni | amine oxidase | 0.0021 | 0.0102 | 0.0218 |
Mycobacterium leprae | Probable S-nitrosomycothiol reductase MscR | 0.015 | 0.4669 | 1 |
Echinococcus multilocularis | protoporphyrinogen oxidase | 0.0021 | 0.0102 | 1 |
Mycobacterium ulcerans | monoamine oxidase | 0.0021 | 0.0102 | 0.0102 |
Brugia malayi | amine oxidase, flavin-containing family protein | 0.0021 | 0.0102 | 0.0218 |
Schistosoma mansoni | Protoporphyrinogen oxidase chloroplast/mitochondrial precursor | 0.0021 | 0.0102 | 0.0218 |
Mycobacterium ulcerans | zinc-dependent alcohol dehydrogenase AdhE2 | 0.015 | 0.4669 | 0.4669 |
Mycobacterium tuberculosis | Possible oxidoreductase | 0.0021 | 0.0102 | 0.011 |
Onchocerca volvulus | Putative alcohol dehydrogenase | 0.015 | 0.4669 | 1 |
Mycobacterium tuberculosis | Probable zinc-type alcohol dehydrogenase AdhD (aldehyde reductase) | 0.015 | 0.4669 | 0.5047 |
Mycobacterium ulcerans | protoporphyrinogen oxidase | 0.0021 | 0.0102 | 0.0102 |
Toxoplasma gondii | histone lysine-specific demethylase LSD1/BHC110/KDMA1A | 0.0021 | 0.0102 | 0.0218 |
Plasmodium vivax | hypothetical protein, conserved | 0.0021 | 0.0102 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0102 | 0.0218 |
Plasmodium vivax | protoporphyrinogen oxidase, putative | 0.0021 | 0.0102 | 0.5 |
Echinococcus granulosus | lysine specific histone demethylase 1A | 0.0021 | 0.0102 | 1 |
Brugia malayi | hypothetical protein | 0.0021 | 0.0102 | 0.0218 |
Echinococcus multilocularis | 0.0021 | 0.0102 | 1 | |
Onchocerca volvulus | 0.0021 | 0.0102 | 0.0218 | |
Toxoplasma gondii | histone lysine-specific demethylase | 0.0021 | 0.0102 | 0.0218 |
Plasmodium falciparum | lysine-specific histone demethylase 1, putative | 0.0021 | 0.0102 | 0.5 |
Schistosoma mansoni | amine oxidase | 0.0021 | 0.0102 | 0.0218 |
Toxoplasma gondii | Zn-containing alcohol dehydrogenase | 0.015 | 0.4669 | 1 |
Plasmodium falciparum | protoporphyrinogen oxidase | 0.0021 | 0.0102 | 0.5 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0021 | 0.0102 | 0.011 |
Loa Loa (eye worm) | alcohol dehydrogenase class III | 0.015 | 0.4669 | 1 |
Leishmania major | UDP-galactopyranose mutase | 0.0021 | 0.0102 | 1 |
Schistosoma mansoni | Lysine-specific histone demethylase 1 | 0.0021 | 0.0102 | 0.0218 |
Chlamydia trachomatis | protoporphyrinogen oxidase | 0.0021 | 0.0102 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0102 | 0.0218 |
Plasmodium vivax | hypothetical protein, conserved | 0.0021 | 0.0102 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0102 | 0.0218 |
Mycobacterium tuberculosis | Probable zinc-type alcohol dehydrogenase (E subunit) AdhE1 | 0.0132 | 0.402 | 0.4346 |
Plasmodium falciparum | conserved Plasmodium protein, unknown function | 0.0021 | 0.0102 | 0.5 |
Schistosoma mansoni | alcohol dehydrogenase | 0.015 | 0.4669 | 1 |
Trypanosoma cruzi | UDP-galactopyranose mutase | 0.0021 | 0.0102 | 1 |
Brugia malayi | SWIRM domain containing protein | 0.0021 | 0.0102 | 0.0218 |
Plasmodium vivax | lysine-specific histone demethylase 1, putative | 0.0021 | 0.0102 | 0.5 |
Brugia malayi | Alcohol dehydrogenase class III | 0.015 | 0.4669 | 1 |
Echinococcus granulosus | lysine specific histone demethylase 1A | 0.0021 | 0.0102 | 1 |
Trypanosoma cruzi | UDP-galactopyranose mutase | 0.0021 | 0.0102 | 1 |
Mycobacterium leprae | PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) | 0.0021 | 0.0102 | 0.0218 |
Mycobacterium ulcerans | dehydrogenase | 0.0021 | 0.0102 | 0.0102 |
Mycobacterium ulcerans | zinc-type alcohol dehydrogenase AdhD | 0.015 | 0.4669 | 0.4669 |
Mycobacterium ulcerans | oxidoreductase | 0.0021 | 0.0102 | 0.0102 |
Mycobacterium ulcerans | zinc-containing alcohol dehydrogenase NAD-dependent AdhB | 0.015 | 0.4669 | 0.4669 |
Mycobacterium ulcerans | zinc-containing alcohol dehydrogenase NAD dependent AdhB | 0.015 | 0.4669 | 0.4669 |
Mycobacterium ulcerans | zinc-dependent alcohol dehydrogenase | 0.015 | 0.4669 | 0.4669 |
Mycobacterium tuberculosis | Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) | 0.028 | 0.925 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.