Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Thioredoxin reductase | 0.0052 | 0.1636 | 0.2085 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0132 | 0.5252 | 0.5206 |
Trichomonas vaginalis | diphosphomevalonate decarboxylase, putative | 0.0031 | 0.0672 | 0.1514 |
Entamoeba histolytica | hypothetical protein | 0.004 | 0.1072 | 0.1046 |
Echinococcus granulosus | SUMO activating enzyme subunit 1 | 0.0053 | 0.1682 | 0.1626 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0119 | 0.4653 | 0.4601 |
Echinococcus multilocularis | SUMO activating enzyme subunit 1 | 0.0053 | 0.1682 | 0.1626 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0021 | 0.0217 | 0.0442 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.004 | 0.1072 | 0.1013 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0052 | 0.1636 | 0.2085 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0086 | 0.3176 | 0.3109 |
Trypanosoma cruzi | ubiquitin-activating enzyme, putative | 0.0035 | 0.086 | 0.0833 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) | 0.0086 | 0.3176 | 0.5514 |
Wolbachia endosymbiont of Brugia malayi | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 0.0073 | 0.2562 | 0.8007 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0018 | 0.0097 | 0.0031 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0113 | 0.4386 | 0.5592 |
Trichomonas vaginalis | galactokinase, putative | 0.011 | 0.4271 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.3176 | 0.4048 |
Trypanosoma brucei | homoserine kinase | 0.0073 | 0.2562 | 0.3182 |
Plasmodium falciparum | SUMO-activating enzyme subunit 2 | 0.0035 | 0.086 | 0.178 |
Trichomonas vaginalis | mevalonate kinase, putative | 0.0031 | 0.0672 | 0.1514 |
Trypanosoma cruzi | galactokinase, putative | 0.0206 | 0.8609 | 0.8605 |
Trypanosoma brucei | mevalonate-diphosphate decarboxylase | 0.0031 | 0.0672 | 0.0742 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.003 | 0.0622 | 0.0618 |
Schistosoma mansoni | hypothetical protein | 0.0113 | 0.4386 | 0.5554 |
Schistosoma mansoni | sumo-1-activating enzyme E1a | 0.0053 | 0.1682 | 0.2077 |
Trichomonas vaginalis | galactokinase, putative | 0.0042 | 0.1171 | 0.2691 |
Schistosoma mansoni | mevalonate kinase | 0.0073 | 0.2562 | 0.3209 |
Leishmania major | phosphomevalonate kinase protein, putative | 0.0073 | 0.2562 | 0.2489 |
Echinococcus multilocularis | Mevalonate galactokinase | 0.0073 | 0.2562 | 0.2512 |
Echinococcus granulosus | peptidase Clp S14 family | 0.0056 | 0.1834 | 0.1779 |
Treponema pallidum | hypothetical protein | 0.0073 | 0.2562 | 0.2896 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0021 | 0.0217 | 0.0122 |
Loa Loa (eye worm) | hypothetical protein | 0.0167 | 0.6807 | 0.8678 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0017 | 0.0066 | 0.0084 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.004 | 0.1072 | 0.1013 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0018 | 0.0097 | 0.0067 |
Onchocerca volvulus | 0.0167 | 0.6807 | 1 | |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0086 | 0.3176 | 1 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0018 | 0.0097 | 0.0067 |
Plasmodium falciparum | thioredoxin reductase | 0.0052 | 0.1636 | 0.3588 |
Toxoplasma gondii | ThiF family protein | 0.0035 | 0.086 | 0.178 |
Trypanosoma brucei | mevalonate kinase, putative | 0.0073 | 0.2562 | 0.3182 |
Toxoplasma gondii | thioredoxin reductase | 0.0052 | 0.1636 | 0.3588 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0021 | 0.0217 | 0.0741 |
Echinococcus granulosus | Mevalonate galactokinase | 0.0073 | 0.2562 | 0.2512 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0113 | 0.4386 | 0.5592 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0599 | 0.0764 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0021 | 0.0217 | 0.0122 |
Brugia malayi | glutathione reductase | 0.0052 | 0.1636 | 0.2085 |
Schistosoma mansoni | lamin | 0.003 | 0.0624 | 0.0717 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0119 | 0.4653 | 0.8705 |
Trypanosoma cruzi | phosphomevalonate kinase protein, putative | 0.0031 | 0.0672 | 0.0644 |
Schistosoma mansoni | sumo-1-activating enzyme E1a | 0.0048 | 0.1461 | 0.1793 |
Trypanosoma brucei | trypanothione reductase | 0.0052 | 0.1636 | 0.1986 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.0189 | 0.7844 | 1 |
Plasmodium vivax | SUMO-activating enzyme subunit 2, putative | 0.0035 | 0.086 | 0.2481 |
Echinococcus multilocularis | carbonic anhydrase | 0.0113 | 0.4386 | 0.4349 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0086 | 0.3176 | 0.7178 |
Echinococcus granulosus | carbonic anhydrase | 0.0113 | 0.4386 | 0.4349 |
Entamoeba histolytica | hypothetical protein | 0.004 | 0.1072 | 0.1046 |
Brugia malayi | hypothetical protein | 0.004 | 0.1072 | 0.1367 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0021 | 0.0217 | 0.0142 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0624 | 0.0795 |
Trypanosoma cruzi | ubiquitin-activating enzyme, putative | 0.003 | 0.064 | 0.0612 |
Echinococcus granulosus | carbonic anhydrase II | 0.0189 | 0.7844 | 0.783 |
Loa Loa (eye worm) | intermediate filament protein | 0.003 | 0.0624 | 0.0795 |
Brugia malayi | MH2 domain containing protein | 0.0132 | 0.5227 | 0.6663 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) | 0.0056 | 0.1834 | 0.2616 |
Toxoplasma gondii | exonuclease III APE | 0.0021 | 0.0217 | 0.0281 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0113 | 0.4386 | 0.5592 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0086 | 0.3176 | 0.3109 |
Trichomonas vaginalis | galactokinase, putative | 0.011 | 0.4271 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0672 | 0.0856 |
Brugia malayi | galactokinase family protein | 0.011 | 0.4271 | 0.5445 |
Schistosoma mansoni | ap endonuclease | 0.0021 | 0.0217 | 0.0194 |
Schistosoma mansoni | carbonic anhydrase | 0.0113 | 0.4386 | 0.5554 |
Plasmodium falciparum | SUMO-activating enzyme subunit 1 | 0.0053 | 0.1682 | 0.3695 |
Echinococcus granulosus | N acetylgalactosamine kinase | 0.011 | 0.4271 | 0.4233 |
Brugia malayi | hypothetical protein | 0.0167 | 0.6807 | 0.8678 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.0189 | 0.7844 | 1 |
Leishmania major | carbonic anhydrase-like protein | 0.0189 | 0.7844 | 0.7823 |
Brugia malayi | Putative carbonic anhydrase 5 precursor | 0.0189 | 0.7844 | 1 |
Treponema pallidum | galactokinase | 0.0206 | 0.8609 | 1 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0132 | 0.5252 | 1 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0086 | 0.3176 | 0.3617 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0086 | 0.3176 | 1 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0021 | 0.0217 | 0.0392 |
Echinococcus multilocularis | carbonic anhydrase II | 0.0189 | 0.7844 | 0.783 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0055 | 0.1763 | 0.2248 |
Schistosoma mansoni | carbonic anhydrase-related | 0.0113 | 0.4386 | 0.5554 |
Echinococcus granulosus | carbonic anhydrase | 0.0113 | 0.4386 | 0.4349 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0028 | 0.0536 | 0.0508 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0028 | 0.0536 | 0.0508 |
Echinococcus multilocularis | N acetylgalactosamine kinase | 0.011 | 0.4271 | 0.4233 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0132 | 0.5227 | 0.6663 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.004 | 0.1072 | 0.1294 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0052 | 0.1636 | 0.1554 |
Brugia malayi | hypothetical protein | 0.0135 | 0.5383 | 0.6862 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent Clp protease proteolytic subunit | 0.0086 | 0.3176 | 1 |
Schistosoma mansoni | lamin | 0.003 | 0.0624 | 0.0717 |
Trypanosoma brucei | phosphomevalonate kinase protein, putative | 0.0073 | 0.2562 | 0.3182 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0018 | 0.0097 | 0.0158 |
Trypanosoma cruzi | fucose kinase, putative | 0.0042 | 0.1171 | 0.1145 |
Schistosoma mansoni | ap endonuclease | 0.0021 | 0.0217 | 0.0194 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0021 | 0.0217 | 0.0442 |
Brugia malayi | hypothetical protein | 0.0018 | 0.0091 | 0.0116 |
Echinococcus granulosus | carbonic anhydrase | 0.0113 | 0.4386 | 0.4349 |
Loa Loa (eye worm) | hypothetical protein | 0.0135 | 0.5383 | 0.6862 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0018 | 0.0097 | 0.0158 |
Leishmania major | mevalonate kinase, putative | 0.0073 | 0.2562 | 0.2489 |
Echinococcus granulosus | ATP dependent Clp protease proteolytic subunit | 0.0086 | 0.3176 | 0.313 |
Leishmania major | homoserine kinase, putative | 0.0073 | 0.2562 | 0.2489 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0018 | 0.0097 | 0.0067 |
Echinococcus multilocularis | ATP dependent Clp protease proteolytic subunit | 0.0086 | 0.3176 | 0.313 |
Loa Loa (eye worm) | carbonic anhydrase 3 | 0.0189 | 0.7844 | 1 |
Leishmania major | mevalonate-diphosphate decarboxylase, putative | 0.0031 | 0.0672 | 0.0581 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0018 | 0.0097 | 0.0067 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.005 | 0.1559 | 0.1503 |
Trypanosoma cruzi | homoserine kinase | 0.0073 | 0.2562 | 0.254 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0086 | 0.3176 | 0.7178 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0021 | 0.0217 | 0.0277 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0052 | 0.1636 | 0.1611 |
Trypanosoma cruzi | mevalonate-diphosphate decarboxylase, putative | 0.0031 | 0.0672 | 0.0644 |
Onchocerca volvulus | Huntingtin homolog | 0.0135 | 0.5383 | 0.7696 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0021 | 0.0217 | 0.0156 |
Trypanosoma brucei | carbonic anhydrase-like protein | 0.0189 | 0.7844 | 1 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.0189 | 0.7844 | 1 |
Echinococcus granulosus | diphosphomevalonate decarboxylase | 0.0031 | 0.0672 | 0.061 |
Giardia lamblia | Diphosphomevalonate decarboxylase | 0.0031 | 0.0672 | 0.2535 |
Brugia malayi | ThiF family protein | 0.0035 | 0.086 | 0.1097 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0018 | 0.0097 | 0.0031 |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.0113 | 0.4386 | 0.5592 |
Brugia malayi | hypothetical protein | 0.0028 | 0.0536 | 0.0683 |
Mycobacterium tuberculosis | Probable reductase | 0.0119 | 0.4653 | 0.4601 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0021 | 0.0217 | 0.0392 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.005 | 0.1559 | 0.1987 |
Brugia malayi | intermediate filament protein | 0.003 | 0.0624 | 0.0795 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.1559 | 0.1919 |
Loa Loa (eye worm) | hypothetical protein | 0.0135 | 0.5383 | 0.6862 |
Plasmodium falciparum | carbonic anhydrase | 0.0113 | 0.4386 | 1 |
Schistosoma mansoni | carbonic anhydrase-related | 0.0113 | 0.4386 | 0.5554 |
Leishmania major | hypothetical protein, conserved | 0.0028 | 0.0536 | 0.0444 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0132 | 0.5252 | 0.5206 |
Schistosoma mansoni | diphosphomevalonate decarboxylase | 0.0031 | 0.0672 | 0.0778 |
Mycobacterium ulcerans | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 0.0073 | 0.2562 | 0.2489 |
Leishmania major | fucose kinase, putative | 0.0031 | 0.0672 | 0.0581 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.0189 | 0.7844 | 0.7838 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0021 | 0.0217 | 0.0152 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.003 | 0.0624 | 0.0795 |
Loa Loa (eye worm) | glutathione reductase | 0.0052 | 0.1636 | 0.2085 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0055 | 0.1763 | 0.2248 |
Trypanosoma cruzi | mevalonate-diphosphate decarboxylase, putative | 0.0031 | 0.0672 | 0.0644 |
Giardia lamblia | Mevalonate kinase | 0.0073 | 0.2562 | 1 |
Leishmania major | trypanothione reductase | 0.0052 | 0.1636 | 0.1554 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 0.4386 | 0.5592 |
Echinococcus granulosus | lamin dm0 | 0.003 | 0.0624 | 0.0561 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0018 | 0.0097 | 0.0265 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0132 | 0.5227 | 0.6663 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0052 | 0.1636 | 0.4999 |
Mycobacterium tuberculosis | Possible D-alpha-D-heptose-7-phosphate kinase HddA | 0.0073 | 0.2562 | 0.2489 |
Toxoplasma gondii | hypothetical protein | 0.0113 | 0.4386 | 1 |
Mycobacterium leprae | PROBABLE HOMOSERINE KINASE THRB | 0.0031 | 0.0672 | 0.0106 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0066 | 0.0084 |
Schistosoma mansoni | intermediate filament proteins | 0.003 | 0.0624 | 0.0717 |
Echinococcus granulosus | sumo-activating enzyme subunit 2 | 0.0035 | 0.086 | 0.08 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0028 | 0.0536 | 0.1427 |
Mycobacterium ulcerans | homoserine kinase | 0.0073 | 0.2562 | 0.2489 |
Toxoplasma gondii | GHMP kinase, N-terminal domain-containing protein | 0.011 | 0.4271 | 0.9731 |
Brugia malayi | mevalonate kinase family protein | 0.0073 | 0.2562 | 0.3266 |
Trypanosoma cruzi | mevalonate kinase, putative | 0.0073 | 0.2562 | 0.254 |
Toxoplasma gondii | hypothetical protein | 0.003 | 0.0622 | 0.1226 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.005 | 0.1559 | 0.1503 |
Loa Loa (eye worm) | ThiF family protein | 0.0035 | 0.086 | 0.1097 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0021 | 0.0217 | 0.0152 |
Echinococcus multilocularis | peptidase Clp (S14 family) | 0.0056 | 0.1834 | 0.1779 |
Mycobacterium ulcerans | mevalonate kinase, Erg12 | 0.0073 | 0.2562 | 0.2489 |
Echinococcus multilocularis | musashi | 0.003 | 0.0624 | 0.0561 |
Loa Loa (eye worm) | galactokinase | 0.011 | 0.4271 | 0.5445 |
Trichomonas vaginalis | galactokinase, putative | 0.011 | 0.4271 | 1 |
Schistosoma mansoni | ubiquitin-activating enzyme E1b | 0.0035 | 0.086 | 0.1021 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0052 | 0.1636 | 0.158 |
Leishmania major | fucose kinase, putative | 0.0031 | 0.0672 | 0.0581 |
Brugia malayi | Probable ClpP-like protease | 0.0086 | 0.3176 | 0.4048 |
Trypanosoma cruzi | galactokinase-like protein, putative | 0.0206 | 0.8609 | 0.8605 |
Plasmodium vivax | glutathione reductase, putative | 0.0052 | 0.1636 | 0.4999 |
Schistosoma mansoni | carbonic anhydrase-related | 0.0113 | 0.4386 | 0.5554 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0021 | 0.0217 | 0.0122 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0119 | 0.4653 | 0.4601 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.005 | 0.1559 | 0.1503 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0119 | 0.4653 | 0.4601 |
Toxoplasma gondii | GHMP kinase, putative | 0.0073 | 0.2562 | 0.5747 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) | 0.0056 | 0.1834 | 0.1754 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.003 | 0.0622 | 0.1708 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0021 | 0.0217 | 0.0188 |
Trichomonas vaginalis | galactokinase, putative | 0.0031 | 0.0672 | 0.1514 |
Mycobacterium ulcerans | phosphomevalonate kinase | 0.0073 | 0.2562 | 0.2489 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.0113 | 0.4386 | 0.5592 |
Echinococcus multilocularis | diphosphomevalonate decarboxylase | 0.0031 | 0.0672 | 0.061 |
Echinococcus granulosus | intermediate filament protein | 0.003 | 0.0624 | 0.0561 |
Trypanosoma brucei | ubiquitin-activating enzyme E1, putative | 0.0035 | 0.086 | 0.0986 |
Trypanosoma brucei | mevalonate diphosphate decarboxylase | 0.0031 | 0.0672 | 0.0742 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.003 | 0.0622 | 0.1226 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.1763 | 0.2248 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0978 | 0.1247 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0052 | 0.1636 | 0.158 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.1559 | 0.1919 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.2562 | 0.3266 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.1072 | 0.1294 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0028 | 0.0536 | 0.1024 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0018 | 0.0097 | 0.0067 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0028 | 0.0536 | 0.0567 |
Schistosoma mansoni | hypothetical protein | 0.0038 | 0.0978 | 0.1172 |
Mycobacterium tuberculosis | Probable homoserine kinase ThrB | 0.0031 | 0.0672 | 0.0581 |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.0113 | 0.4386 | 0.5592 |
Echinococcus multilocularis | carbonic anhydrase | 0.0113 | 0.4386 | 0.4349 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0086 | 0.3176 | 0.7178 |
Trypanosoma brucei | galactokinase-like protein, putative | 0.0158 | 0.6401 | 0.8137 |
Onchocerca volvulus | 0.0031 | 0.0672 | 0.0077 | |
Schistosoma mansoni | peptidase Clp (S14 family) | 0.0086 | 0.3176 | 0.3998 |
Chlamydia trachomatis | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 0.0031 | 0.0672 | 0.1867 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0536 | 0.0683 |
Trypanosoma cruzi | fucose kinase, putative | 0.0042 | 0.1171 | 0.1145 |
Echinococcus multilocularis | SUMO activating enzyme subunit 2 | 0.0035 | 0.086 | 0.08 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0132 | 0.5252 | 0.5206 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0028 | 0.0536 | 0.1024 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.1559 | 0.1919 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0021 | 0.0217 | 0.0188 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0055 | 0.1763 | 0.2248 |
Plasmodium vivax | ubiquitin activating enzyme, putative | 0.0053 | 0.1682 | 0.5148 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.005 | 0.1559 | 0.1987 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0119 | 0.4653 | 0.4601 |
Echinococcus multilocularis | carbonic anhydrase | 0.0113 | 0.4386 | 0.4349 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0017 | 0.0066 | 0.0084 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0119 | 0.4653 | 0.4601 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0018 | 0.0097 | 0.0067 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 0.4386 | 0.5592 |
Entamoeba histolytica | hypothetical protein | 0.004 | 0.1072 | 0.1046 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 0.4386 | 0.5592 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0038 | 0.0978 | 0.1247 |
Brugia malayi | diphosphomevalonate decarboxylase family protein | 0.0031 | 0.0672 | 0.0856 |
Echinococcus granulosus | lamin | 0.003 | 0.0624 | 0.0561 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.003 | 0.0624 | 0.0795 |
Mycobacterium ulcerans | diphosphomevalonate decarboxylase | 0.0031 | 0.0672 | 0.0581 |
Echinococcus multilocularis | lamin dm0 | 0.003 | 0.0624 | 0.0561 |
Onchocerca volvulus | Huntingtin homolog | 0.0135 | 0.5383 | 0.7696 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0018 | 0.0097 | 0.0067 |
Plasmodium falciparum | glutathione reductase | 0.0052 | 0.1636 | 0.3588 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0018 | 0.0097 | 0.0123 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.005 | 0.1559 | 0.1503 |
Trichomonas vaginalis | galactokinase, putative | 0.011 | 0.4271 | 1 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) | 0.0056 | 0.1834 | 0.1754 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0021 | 0.0217 | 0.0188 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.1682 | 0.2144 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0017 | 0.0066 | 0.0084 |
Brugia malayi | ThiF family protein | 0.0053 | 0.1682 | 0.2144 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0031 | 0.0672 | 0.1514 |
Entamoeba histolytica | hypothetical protein | 0.004 | 0.1072 | 0.1046 |
Leishmania major | ubiquitin-activating enzyme-like protein | 0.0035 | 0.086 | 0.0771 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0018 | 0.0097 | 0.0067 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0021 | 0.0217 | 0.0281 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0086 | 0.3176 | 1 |
Echinococcus multilocularis | lamin | 0.003 | 0.0624 | 0.0561 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0021 | 0.0217 | 0.0277 |
Schistosoma mansoni | galactokinase | 0.011 | 0.4271 | 0.5406 |
Mycobacterium leprae | Probable 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase IspE (CMK) (4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase) | 0.0073 | 0.2562 | 0.4189 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0018 | 0.0097 | 0.0039 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0018 | 0.0097 | 0.0067 |
Toxoplasma gondii | hypothetical protein | 0.0053 | 0.1682 | 0.3695 |
Trypanosoma cruzi | homoserine kinase | 0.0073 | 0.2562 | 0.254 |
Trypanosoma cruzi | phosphomevalonate kinase protein, putative | 0.0031 | 0.0672 | 0.0644 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.0189 | 0.7844 | 0.7838 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0189 | 0.7844 | 1 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0028 | 0.0536 | 0.1024 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.