Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0468 | 0.0927 | 1 |
Schistosoma mansoni | ferritin light chain | 0.0017 | 0.0011 | 0.0011 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0468 | 0.0927 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0074 | 0.0125 | 0.5444 |
Echinococcus multilocularis | tar DNA binding protein | 0.0129 | 0.0238 | 0.0424 |
Echinococcus multilocularis | protein dispatched 1 | 0.0055 | 0.0088 | 0.0156 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0045 | 0.0045 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0017 | 0.003 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0364 | 0.0716 | 0.0716 |
Brugia malayi | Uncoordinated protein 44 | 0.0036 | 0.0049 | 0.0087 |
Schistosoma mansoni | apoferritin-2 | 0.0017 | 0.0011 | 0.0011 |
Loa Loa (eye worm) | hypothetical protein | 0.099 | 0.1987 | 0.3544 |
Schistosoma mansoni | apoferritin-2 | 0.0017 | 0.0011 | 0.0011 |
Schistosoma mansoni | ferritin light chain | 0.0017 | 0.0011 | 0.0011 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0364 | 0.0716 | 0.0716 |
Onchocerca volvulus | 0.0052 | 0.0082 | 0.0576 | |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0468 | 0.0927 | 0.1654 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0048 | 0.0074 | 0.0131 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.2771 | 0.5608 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.2771 | 0.5608 | 1 |
Schistosoma mansoni | bromodomain containing protein | 0.0068 | 0.0114 | 0.0114 |
Schistosoma mansoni | thyroid hormone receptor | 0.0133 | 0.0247 | 0.0247 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0531 | 0.1055 | 0.1882 |
Echinococcus multilocularis | nuclear factor of activated T cells 5 | 0.0353 | 0.0694 | 0.1237 |
Mycobacterium leprae | conserved hypothetical protein | 0.0036 | 0.0049 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0364 | 0.0716 | 0.1277 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0036 | 0.0049 | 0.0417 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.0049 | 0.0417 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0468 | 0.0927 | 0.0927 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0364 | 0.0716 | 0.0716 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0031 | 0.0055 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0017 | 0.003 |
Brugia malayi | Bromodomain containing protein | 0.0041 | 0.0059 | 0.0106 |
Echinococcus granulosus | neuropeptide s receptor | 0.0531 | 0.1055 | 0.1882 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0024 | 0.0025 | 0.0025 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.0008 | 0.0014 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0048 | 0.0074 | 0.0131 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0034 | 0.0045 | 0.008 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0123 | 0.0227 | 0.0404 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0036 | 0.0049 | 0.0417 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0036 | 0.0049 | 0.0417 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.007 | 0.007 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0027 | 0.0031 | 0.0214 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.0096 | 0.0171 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0027 | 0.0031 | 0.2007 |
Plasmodium vivax | plasmepsin V, putative | 0.0364 | 0.0716 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0017 | 0.003 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.2771 | 0.5608 | 0.5608 |
Schistosoma mansoni | hypothetical protein | 0.0123 | 0.0227 | 0.0227 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0114 | 0.0208 | 0.0208 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0027 | 0.0031 | 0.0214 |
Loa Loa (eye worm) | TAR-binding protein | 0.0129 | 0.0238 | 0.0424 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0069 | 0.0117 | 0.0117 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0036 | 0.0049 | 0.0088 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0074 | 0.0125 | 0.0125 |
Onchocerca volvulus | 0.003 | 0.0036 | 0.0065 | |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0049 | 0.0088 |
Brugia malayi | beta-lactamase | 0.0036 | 0.0049 | 0.0088 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.007 | 0.007 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0008 | 0.0014 |
Loa Loa (eye worm) | hypothetical protein | 0.0364 | 0.0716 | 0.1277 |
Trichomonas vaginalis | Clan AA, family A1, cathepsin D-like aspartic peptidase | 0.0364 | 0.0716 | 0.7693 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0468 | 0.0927 | 0.1654 |
Plasmodium vivax | aspartyl protease, putative | 0.0364 | 0.0716 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0074 | 0.0131 |
Echinococcus granulosus | expressed protein | 0.0017 | 0.0011 | 0.002 |
Schistosoma mansoni | ferritin | 0.0017 | 0.0011 | 0.0011 |
Brugia malayi | Carboxylesterase family protein | 0.2771 | 0.5608 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0468 | 0.0927 | 0.0927 |
Echinococcus granulosus | death domain containing protein | 0.0036 | 0.0049 | 0.0087 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0049 | 0.0049 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0231 | 0.0446 | 0.4748 |
Mycobacterium leprae | Probable lipase LipE | 0.0036 | 0.0049 | 1 |
Plasmodium falciparum | plasmepsin V | 0.0364 | 0.0716 | 1 |
Echinococcus multilocularis | neuroligin | 0.0468 | 0.0927 | 0.1654 |
Onchocerca volvulus | 0.0468 | 0.0927 | 1 | |
Brugia malayi | Ets-domain containing protein | 0.0083 | 0.0144 | 0.0256 |
Echinococcus granulosus | tar DNA binding protein | 0.0129 | 0.0238 | 0.0424 |
Brugia malayi | PHD-finger family protein | 0.0027 | 0.003 | 0.0054 |
Brugia malayi | hypothetical protein | 0.0364 | 0.0716 | 0.1277 |
Brugia malayi | CHE-14 protein | 0.0048 | 0.0074 | 0.0131 |
Schistosoma mansoni | ets-related | 0.0251 | 0.0486 | 0.0486 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0048 | 0.0074 | 0.0074 |
Brugia malayi | aspartic protease BmAsp-2, identical | 0.0364 | 0.0716 | 0.1277 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0008 | 0.0008 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0036 | 0.0049 | 0.0417 |
Plasmodium falciparum | plasmepsin IX | 0.0364 | 0.0716 | 1 |
Echinococcus granulosus | methyl CpG binding domain protein 2 | 0.0018 | 0.0013 | 0.0023 |
Toxoplasma gondii | eukaryotic aspartyl protease superfamily protein | 0.0364 | 0.0716 | 1 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0036 | 0.0049 | 0.0417 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0091 | 0.0161 | 0.0287 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0036 | 0.0049 | 0.0088 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0036 | 0.0049 | 0.0417 |
Mycobacterium ulcerans | lipase LipD | 0.0036 | 0.0049 | 0.0417 |
Echinococcus granulosus | zinc finger protein | 0.0021 | 0.0018 | 0.0033 |
Loa Loa (eye worm) | hypothetical protein | 0.0468 | 0.0927 | 0.1654 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0019 | 0.0014 | 0.0038 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0069 | 0.0117 | 0.0208 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0069 | 0.0117 | 0.118 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0049 | 0.0088 |
Toxoplasma gondii | aspartyl protease | 0.0364 | 0.0716 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0031 | 0.0055 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0019 | 0.0014 | 0.0038 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0531 | 0.1055 | 0.1882 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0069 | 0.0117 | 0.1152 |
Mycobacterium ulcerans | beta-lactamase | 0.0036 | 0.0049 | 0.0417 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0019 | 0.0014 | 0.0038 |
Plasmodium falciparum | plasmepsin III | 0.0364 | 0.0716 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0048 | 0.0074 | 0.0684 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0468 | 0.0927 | 0.1654 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.002 | 0.0017 | 0.0062 |
Schistosoma mansoni | tar DNA-binding protein | 0.0129 | 0.0238 | 0.0238 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0045 | 0.008 |
Echinococcus granulosus | netrin receptor unc 5 | 0.0036 | 0.0049 | 0.0087 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.1636 | 0.3301 | 0.5886 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0091 | 0.0161 | 0.0287 |
Schistosoma mansoni | ankyrin 23/unc44 | 0.0036 | 0.0049 | 0.0049 |
Echinococcus granulosus | neuroligin | 0.0468 | 0.0927 | 0.1654 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 0.0204 | 0.0364 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0036 | 0.0049 | 1 |
Brugia malayi | Death domain containing protein | 0.0036 | 0.0049 | 0.0087 |
Loa Loa (eye worm) | aspartic protease BmAsp-2 | 0.0364 | 0.0716 | 0.1277 |
Plasmodium falciparum | plasmepsin X | 0.0364 | 0.0716 | 1 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0018 | 0.0013 | 0.0013 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0468 | 0.0927 | 1 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0036 | 0.0049 | 0.0417 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0017 | 0.003 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0016 | 0.0008 | 0.0014 |
Schistosoma mansoni | patched 1 | 0.0048 | 0.0074 | 0.0074 |
Schistosoma mansoni | alzheimer's disease beta-amyloid related | 0.0853 | 0.1708 | 0.1708 |
Echinococcus multilocularis | acetylcholinesterase | 0.2771 | 0.5608 | 1 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.0112 | 0.0204 | 0.0364 |
Loa Loa (eye worm) | hypothetical protein | 0.2771 | 0.5608 | 1 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0069 | 0.0117 | 0.0208 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0468 | 0.0927 | 0.0927 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0052 | 0.0082 | 0.0082 |
Brugia malayi | RNA binding protein | 0.0129 | 0.0238 | 0.0424 |
Brugia malayi | Pre-SET motif family protein | 0.0209 | 0.04 | 0.0713 |
Brugia malayi | Carboxylesterase family protein | 0.0468 | 0.0927 | 0.1654 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0036 | 0.0049 | 0.0417 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0069 | 0.0117 | 0.1152 |
Toxoplasma gondii | aspartyl proteinase (eimepsin), putative | 0.0364 | 0.0716 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0129 | 0.0238 | 0.0238 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0027 | 0.0031 | 0.0214 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0019 | 0.0014 | 0.0025 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.006 | 0.0106 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.0008 | 0.0014 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0077 | 0.0138 |
Onchocerca volvulus | 0.0468 | 0.0927 | 1 | |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0133 | 0.0247 | 0.044 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0161 | 0.0302 | 0.0539 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0008 | 0.0008 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0036 | 0.0049 | 0.0088 |
Brugia malayi | Pepsin A precursor | 0.0364 | 0.0716 | 0.1277 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0039 | 0.0054 | 0.0097 |
Loa Loa (eye worm) | beta-lactamase | 0.0036 | 0.0049 | 0.0088 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0024 | 0.0025 | 0.0044 |
Plasmodium vivax | SET domain protein, putative | 0.003 | 0.0036 | 0.0282 |
Plasmodium vivax | aspartyl protease, putative | 0.0364 | 0.0716 | 1 |
Plasmodium falciparum | plasmepsin VIII, putative | 0.0364 | 0.0716 | 1 |
Plasmodium vivax | hypothetical protein, conserved | 0.0036 | 0.0049 | 0.0465 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0024 | 0.0025 | 0.0044 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0019 | 0.0014 | 0.0038 |
Mycobacterium ulcerans | hypothetical protein | 0.0027 | 0.0031 | 0.0214 |
Plasmodium vivax | aspartyl proteinase, putative | 0.0364 | 0.0716 | 1 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0016 | 0.0008 | 0.0014 |
Loa Loa (eye worm) | carboxylesterase | 0.0468 | 0.0927 | 0.1654 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0069 | 0.0123 |
Echinococcus multilocularis | tumor protein p63 | 0.0359 | 0.0704 | 0.1256 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0065 | 0.0115 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0018 | 0.0013 | 0.0013 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.002 | 0.0017 | 0.5 |
Schistosoma mansoni | acetylcholinesterase | 0.0468 | 0.0927 | 0.0927 |
Brugia malayi | Fli-1 protein | 0.0251 | 0.0486 | 0.0867 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.003 | 0.0036 | 0.0065 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.007 | 0.007 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0027 | 0.0031 | 0.0214 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0112 | 0.0204 | 0.0364 |
Entamoeba histolytica | hypothetical protein | 0.0074 | 0.0125 | 0.5444 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0468 | 0.0927 | 0.0927 |
Echinococcus granulosus | Ankyrin | 0.0036 | 0.0049 | 0.0088 |
Brugia malayi | AMP-binding enzyme family protein | 0.0027 | 0.0031 | 0.0055 |
Loa Loa (eye worm) | aspartyl protease 6 | 0.0364 | 0.0716 | 0.1277 |
Entamoeba histolytica | hypothetical protein | 0.0074 | 0.0125 | 0.5444 |
Loa Loa (eye worm) | hypothetical protein | 0.1842 | 0.372 | 0.6634 |
Schistosoma mansoni | thyroid hormone receptor | 0.0133 | 0.0247 | 0.0247 |
Schistosoma mansoni | tar DNA-binding protein | 0.0129 | 0.0238 | 0.0238 |
Schistosoma mansoni | ferritin | 0.0017 | 0.0011 | 0.0011 |
Echinococcus multilocularis | expressed protein | 0.0017 | 0.0011 | 0.002 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0049 | 1 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0364 | 0.0716 | 0.0716 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0036 | 0.0049 | 0.0417 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.0008 | 0.0014 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0091 | 0.0161 | 0.0161 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.005 | 0.0077 | 0.0138 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0788 | 0.1578 | 0.1578 |
Loa Loa (eye worm) | hypothetical protein | 0.2771 | 0.5608 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0009 | 0.0009 |
Onchocerca volvulus | Netrin receptor homolog | 0.0036 | 0.0049 | 0.0205 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0468 | 0.0927 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0468 | 0.0927 | 0.1654 |
Schistosoma mansoni | tar DNA-binding protein | 0.0129 | 0.0238 | 0.0238 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0091 | 0.0161 | 0.0287 |
Echinococcus multilocularis | Ankyrin | 0.0036 | 0.0049 | 0.0088 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0027 | 0.0031 | 0.5134 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0082 | 0.0147 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.0112 | 0.0204 | 1 |
Plasmodium falciparum | plasmepsin I | 0.0364 | 0.0716 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0027 | 0.0031 | 0.0214 |
Brugia malayi | Protein kinase domain containing protein | 0.0036 | 0.0049 | 0.0087 |
Brugia malayi | hypothetical protein | 0.0074 | 0.0125 | 0.0223 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0364 | 0.0716 | 0.0716 |
Echinococcus granulosus | carboxylesterase 5A | 0.2771 | 0.5608 | 1 |
Echinococcus granulosus | GPCR family 2 | 0.0016 | 0.0008 | 0.0014 |
Onchocerca volvulus | 0.0468 | 0.0927 | 1 | |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.005 | 0.0077 | 0.0138 |
Onchocerca volvulus | 0.0036 | 0.0049 | 0.0207 | |
Loa Loa (eye worm) | hypothetical protein | 0.0494 | 0.098 | 0.1748 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.002 | 0.0017 | 0.0062 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0022 | 0.0021 | 0.0037 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0091 | 0.0161 | 0.0287 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0036 | 0.0049 | 0.0417 |
Echinococcus multilocularis | zinc finger protein | 0.0021 | 0.0018 | 0.0033 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0468 | 0.0927 | 1 |
Echinococcus granulosus | tumor protein p63 | 0.0359 | 0.0704 | 0.1256 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.005 | 0.0077 | 0.0138 |
Onchocerca volvulus | 0.0468 | 0.0927 | 1 | |
Echinococcus multilocularis | protein patched | 0.0048 | 0.0074 | 0.0131 |
Echinococcus multilocularis | methyl CpG binding domain protein 2 | 0.0018 | 0.0013 | 0.0023 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0036 | 0.0049 | 0.0087 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0027 | 0.0031 | 0.0214 |
Loa Loa (eye worm) | hypothetical protein | 0.0468 | 0.0927 | 0.1654 |
Brugia malayi | AMP-binding enzyme family protein | 0.0027 | 0.0031 | 0.0055 |
Schistosoma mansoni | ferritin | 0.0017 | 0.0011 | 0.0011 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0008 | 0.0008 |
Onchocerca volvulus | 0.0238 | 0.0459 | 0.4776 | |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0468 | 0.0927 | 0.1654 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0036 | 0.0049 | 0.0049 |
Loa Loa (eye worm) | aspartic protease BmAsp-1 | 0.0364 | 0.0716 | 0.1277 |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.0049 | 0.0417 |
Treponema pallidum | bacterioferrin (TpF1) | 0.0017 | 0.0011 | 0.5 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0468 | 0.0927 | 0.1654 |
Brugia malayi | Carboxylesterase family protein | 0.0468 | 0.0927 | 0.1654 |
Onchocerca volvulus | 0.0036 | 0.0049 | 0.0207 | |
Plasmodium falciparum | plasmepsin II | 0.0364 | 0.0716 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0048 | 0.0074 | 0.0074 |
Brugia malayi | Carboxylesterase family protein | 0.2771 | 0.5608 | 1 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0039 | 0.0054 | 0.0097 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0008 | 0.0008 |
Brugia malayi | Pre-SET motif family protein | 0.003 | 0.0036 | 0.0065 |
Echinococcus granulosus | cathepsin d lysosomal aspartyl protease | 0.0364 | 0.0716 | 0.1277 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.0049 | 0.0417 |
Loa Loa (eye worm) | hypothetical protein | 0.0364 | 0.0716 | 0.1277 |
Loa Loa (eye worm) | hypothetical protein | 0.0468 | 0.0927 | 0.1654 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0048 | 0.0074 | 0.0132 |
Schistosoma mansoni | gliotactin | 0.0468 | 0.0927 | 0.0927 |
Loa Loa (eye worm) | RNA binding protein | 0.0129 | 0.0238 | 0.0424 |
Echinococcus multilocularis | netrin receptor unc 5 | 0.0036 | 0.0049 | 0.0087 |
Wolbachia endosymbiont of Brugia malayi | bacterioferritin/cytochrome b1 | 0.0017 | 0.0011 | 0.5 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0069 | 0.0117 | 0.1152 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0036 | 0.0049 | 0.0087 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0123 | 0.0227 | 0.0404 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0027 | 0.0031 | 0.0214 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0364 | 0.0716 | 0.0716 |
Brugia malayi | aspartic protease BmAsp-1, identical | 0.0364 | 0.0716 | 0.1277 |
Brugia malayi | TAR-binding protein | 0.0129 | 0.0238 | 0.0424 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0016 | 0.0008 | 0.0014 |
Onchocerca volvulus | 0.0364 | 0.0716 | 0.7642 | |
Echinococcus multilocularis | GA binding protein alpha chain | 0.0083 | 0.0144 | 0.0256 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0031 | 0.0055 |
Onchocerca volvulus | 0.0468 | 0.0927 | 1 | |
Echinococcus granulosus | GA binding protein alpha chain | 0.0083 | 0.0144 | 0.0256 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0091 | 0.0161 | 0.0287 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0036 | 0.0049 | 0.0049 |
Schistosoma mansoni | zinc finger protein | 0.0016 | 0.0009 | 0.0009 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0036 | 0.0049 | 0.0088 |
Toxoplasma gondii | ABC1 family protein | 0.0036 | 0.0049 | 0.0188 |
Brugia malayi | Eukaryotic aspartyl protease family protein | 0.0364 | 0.0716 | 0.1277 |
Plasmodium vivax | aspartyl proteinase, putative | 0.0364 | 0.0716 | 1 |
Plasmodium falciparum | plasmepsin VII | 0.0364 | 0.0716 | 1 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0027 | 0.0031 | 0.0214 |
Echinococcus granulosus | expressed conserved protein | 0.0106 | 0.019 | 0.0339 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0129 | 0.0238 | 0.0424 |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.0049 | 0.0417 |
Echinococcus multilocularis | expressed conserved protein | 0.0106 | 0.019 | 0.0339 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0364 | 0.0716 | 0.0716 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0069 | 0.0117 | 0.0117 |
Loa Loa (eye worm) | hypothetical protein | 0.0468 | 0.0927 | 0.1654 |
Loa Loa (eye worm) | carboxylesterase | 0.2771 | 0.5608 | 1 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0531 | 0.1055 | 0.1882 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.007 | 0.007 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0112 | 0.0204 | 0.0364 |
Schistosoma mansoni | cathepsin D (A01 family) | 0.0364 | 0.0716 | 0.0716 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0074 | 0.0132 |
Echinococcus granulosus | acetylcholinesterase | 0.2771 | 0.5608 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0129 | 0.0238 | 0.0238 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0069 | 0.0117 | 1 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0468 | 0.0927 | 0.1654 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0064 | 0.0106 | 0.0189 |
Brugia malayi | Amyloid A4 extracellular domain containing protein | 0.2338 | 0.4727 | 0.843 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0027 | 0.0031 | 0.2007 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0119 | 0.0213 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0029 | 0.0034 | 0.0061 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.013 | 0.0232 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0091 | 0.0161 | 0.0287 |
Leishmania major | hypothetical protein, conserved | 0.0036 | 0.0049 | 0.3735 |
Brugia malayi | Bromodomain containing protein | 0.0081 | 0.014 | 0.0249 |
Schistosoma mansoni | hypothetical protein | 0.0074 | 0.0125 | 0.0125 |
Plasmodium falciparum | plasmepsin VI | 0.0364 | 0.0716 | 1 |
Schistosoma mansoni | gabp alpha | 0.0083 | 0.0144 | 0.0144 |
Schistosoma mansoni | ferritin | 0.0017 | 0.0011 | 0.0011 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0091 | 0.0161 | 0.0161 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0027 | 0.0031 | 0.5134 |
Echinococcus multilocularis | carboxylesterase 5A | 0.2771 | 0.5608 | 1 |
Loa Loa (eye worm) | D-ets-4 DNA binding domain-containing protein | 0.0083 | 0.0144 | 0.0256 |
Schistosoma mansoni | hypothetical protein | 0.0176 | 0.0333 | 0.0333 |
Echinococcus multilocularis | cathepsin d (lysosomal aspartyl protease) | 0.0364 | 0.0716 | 0.1277 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0364 | 0.0716 | 0.0716 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0027 | 0.0031 | 0.0214 |
Schistosoma mansoni | retinoblastoma-binding protein 4 (rbbp4) | 0.0036 | 0.0049 | 0.0049 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0017 | 0.003 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0468 | 0.0927 | 0.0927 |
Loa Loa (eye worm) | hypothetical protein | 0.0468 | 0.0927 | 0.1654 |
Trichomonas vaginalis | set domain proteins, putative | 0.0238 | 0.0459 | 0.4885 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0048 | 0.0074 | 0.0131 |
Onchocerca volvulus | 0.0364 | 0.0716 | 0.7642 | |
Mycobacterium ulcerans | hypothetical protein | 0.0036 | 0.0049 | 0.0417 |
Schistosoma mansoni | zinc finger protein | 0.0021 | 0.0018 | 0.0018 |
Echinococcus multilocularis | ankyrin repeat and death domain containing protein | 0.0036 | 0.0049 | 0.0087 |
Brugia malayi | Carboxylesterase family protein | 0.0468 | 0.0927 | 0.1654 |
Echinococcus multilocularis | geminin | 0.0176 | 0.0333 | 0.0595 |
Loa Loa (eye worm) | fli-1 protein | 0.0251 | 0.0486 | 0.0867 |
Schistosoma mansoni | netrin receptor unc5 | 0.0036 | 0.0049 | 0.0049 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0209 | 0.04 | 0.0713 |
Brugia malayi | Carboxylesterase family protein | 0.0468 | 0.0927 | 0.1654 |
Echinococcus granulosus | ankyrin repeat and death domain containing protein | 0.0036 | 0.0049 | 0.0087 |
Plasmodium falciparum | plasmepsin IV | 0.0364 | 0.0716 | 1 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0364 | 0.0716 | 0.0716 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0091 | 0.0161 | 0.0161 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.0049 | 0.0417 |
Plasmodium vivax | plasmepsin IV, putative | 0.0364 | 0.0716 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0049 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0049 | 0.0088 |
Brugia malayi | hypothetical protein | 0.0468 | 0.0927 | 0.1654 |
Echinococcus granulosus | ferritin | 0.0017 | 0.0011 | 0.002 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.0008 | 0.0014 |
Schistosoma mansoni | cathepsin D (A01 family) | 0.0364 | 0.0716 | 0.0716 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0161 | 0.0302 | 0.0539 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0074 | 0.0125 | 0.0223 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0049 | 0.0088 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0074 | 0.0125 | 0.0223 |
Loa Loa (eye worm) | hypothetical protein | 0.0468 | 0.0927 | 0.1654 |
Echinococcus multilocularis | GPCR, family 2 | 0.0016 | 0.0008 | 0.0014 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0036 | 0.0036 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0048 | 0.0074 | 0.0131 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0036 | 0.0049 | 0.0417 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0468 | 0.0927 | 1 |
Brugia malayi | Ets-domain containing protein | 0.0083 | 0.0144 | 0.0256 |
Toxoplasma gondii | aspartyl protease ASP1 | 0.0364 | 0.0716 | 1 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0129 | 0.0238 | 0.0424 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0049 | 0.0088 |
Brugia malayi | beta-lactamase family protein | 0.0036 | 0.0049 | 0.0088 |
Brugia malayi | hypothetical protein | 0.0364 | 0.0716 | 0.1277 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.003 | 0.0036 | 0.0036 |
Entamoeba histolytica | hypothetical protein | 0.0074 | 0.0125 | 0.5444 |
Onchocerca volvulus | 0.0036 | 0.0049 | 0.0207 | |
Echinococcus granulosus | geminin | 0.0176 | 0.0333 | 0.0595 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0788 | 0.1578 | 0.2814 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0049 | 0.0087 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0027 | 0.0031 | 0.2007 |
Brugia malayi | AMP-binding enzyme family protein | 0.0027 | 0.0031 | 0.0055 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0049 | 0.0088 |
Toxoplasma gondii | aspartyl protease ASP3 | 0.0364 | 0.0716 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0049 | 0.0088 |
Echinococcus multilocularis | acetylcholinesterase | 0.2771 | 0.5608 | 1 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0064 | 0.0106 | 0.0189 |
Echinococcus multilocularis | ferritin | 0.0017 | 0.0011 | 0.002 |
Trichomonas vaginalis | esterase, putative | 0.0036 | 0.0049 | 0.0417 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0788 | 0.1578 | 0.2814 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0069 | 0.0117 | 0.1152 |
Echinococcus granulosus | nuclear factor of activated T cells 5 | 0.0353 | 0.0694 | 0.1237 |
Plasmodium vivax | aspartyl protease, putative | 0.0364 | 0.0716 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0176 | 0.0333 | 0.0333 |
Loa Loa (eye worm) | carboxylesterase | 0.0468 | 0.0927 | 0.1654 |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.0049 | 0.0417 |
Schistosoma mansoni | hypothetical protein | 0.0022 | 0.0021 | 0.0021 |
Brugia malayi | beta-lactamase family protein | 0.0036 | 0.0049 | 0.0088 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0048 | 0.0074 | 0.0132 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
ED50 (functional) | = 6.3 mg kg-1 | Effective dose required for writhing response in mouse after 20 minutes on sc administration | ChEMBL. | 7901416 |
ED50 (functional) | = 6.8 mg kg-1 | Effective dose required for writhing response in mouse after 20 minutes on ig administration | ChEMBL. | 7901416 |
pA2 (functional) | = 6.5 | Antinociceptive activity against PGE-2 in guinea pig ileum at 3 microM | ChEMBL. | 7901416 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.