Detailed information for compound 184252

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 359.807 | Formula: C18H18ClN3O3
  • H donors: 2 H acceptors: 2 LogP: 3.18 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCC(=O)NNC(=O)N1Cc2ccccc2Oc2c1cc(Cl)cc2
  • InChi: 1S/C18H18ClN3O3/c1-2-5-17(23)20-21-18(24)22-11-12-6-3-4-7-15(12)25-16-9-8-13(19)10-14(16)22/h3-4,6-10H,2,5,11H2,1H3,(H,20,23)(H,21,24)
  • InChiKey: KPSGVFVGURUIHU-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0034 0.0077 0.0088
Echinococcus granulosus suppressor of cytokine signaling 6 0.0317 0.2693 0.3049
Schistosoma mansoni tar DNA-binding protein 0.0123 0.0906 0.1005
Entamoeba histolytica protein kinase, putative 0.0213 0.1733 0.3186
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0058 0.0302 0.0549
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0464 0.4056 0.458
Loa Loa (eye worm) hypothetical protein 0.0213 0.1733 0.1972
Schistosoma mansoni tyrosine kinase 0.0213 0.1733 0.1944
Trypanosoma brucei protein kinase, putative 0.0213 0.1733 0.2955
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0529 0.466 0.5276
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0066 0.0374 0.0423
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0058 0.0302 0.032
Entamoeba histolytica protein kinase, putative 0.0213 0.1733 0.3186
Toxoplasma gondii STE kinase 0.0213 0.1733 0.3326
Echinococcus multilocularis receptor type guanylyl cyclase 0.0213 0.1733 0.1962
Onchocerca volvulus 0.0213 0.1733 0.1733
Entamoeba histolytica serine/threonine kinase, putative 0.0213 0.1733 0.3186
Brugia malayi Protein kinase domain containing protein 0.0213 0.1733 0.1979
Schistosoma mansoni tyrosine kinase 0.0213 0.1733 0.1944
Echinococcus multilocularis thioredoxin glutathione reductase 0.004 0.0135 0.0152
Loa Loa (eye worm) hypothetical protein 0.0317 0.2693 0.3069
Trichomonas vaginalis TKL family protein kinase 0.0213 0.1733 0.1554
Loa Loa (eye worm) hypothetical protein 0.0034 0.0077 0.0079
Schistosoma mansoni hypothetical protein 0.0113 0.0811 0.0897
Loa Loa (eye worm) TK/FER protein kinase 0.0529 0.466 0.5317
Loa Loa (eye worm) isocitrate dehydrogenase 0.0042 0.0151 0.0163
Schistosoma mansoni protein kinase 0.0213 0.1733 0.1944
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0075 0.0461 0.0933
Echinococcus granulosus tyrosine protein kinase csk 0.0213 0.1733 0.1962
Echinococcus multilocularis activated cdc42 kinase 1 0.0213 0.1733 0.1962
Trichomonas vaginalis TKL family protein kinase 0.0213 0.1733 0.1554
Brugia malayi Steroid receptor seven-up type 2 0.0034 0.0077 0.0088
Entamoeba histolytica protein kinase, putative 0.0213 0.1733 0.3186
Schistosoma mansoni hypothetical protein 0.0981 0.8833 1
Loa Loa (eye worm) hypothetical protein 0.0529 0.466 0.5317
Echinococcus multilocularis carbonic anhydrase 0.0218 0.1782 0.2017
Entamoeba histolytica protein kinase, putative 0.0213 0.1733 0.3186
Echinococcus granulosus integrin linked protein kinase 0.0213 0.1733 0.1962
Echinococcus multilocularis RUN 0.0036 0.0102 0.0116
Echinococcus granulosus neuropeptide s receptor 0.0397 0.3432 0.3886
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0317 0.2693 0.3033
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0075 0.0461 0.0604
Loa Loa (eye worm) hypothetical protein 0.0317 0.2693 0.3069
Entamoeba histolytica hypothetical protein 0.0098 0.0673 0.0718
Trichomonas vaginalis TKL family protein kinase 0.0213 0.1733 0.1554
Loa Loa (eye worm) hypothetical protein 0.0317 0.2693 0.3069
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0529 0.466 0.5276
Trichomonas vaginalis TKL family protein kinase 0.0213 0.1733 0.1554
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0213 0.1733 0.1554
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0529 0.466 0.5276
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0213 0.1733 0.1962
Echinococcus granulosus carbonic anhydrase 0.0218 0.1782 0.2017
Echinococcus granulosus retinal guanylyl cyclase 2 0.0213 0.1733 0.1962
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0091 0.0606 0.1544
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0317 0.2693 0.5421
Trichomonas vaginalis conserved hypothetical protein 0.0213 0.1733 0.1554
Echinococcus granulosus tensin C1 domain containing phosphatase 0.0317 0.2693 0.3049
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0218 0.1782 0.2027
Plasmodium falciparum protein kinase, putative 0.0213 0.1733 0.337
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0042 0.0151 0.0171
Loa Loa (eye worm) TK/INSR protein kinase 0.0213 0.1733 0.1972
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0075 0.0461 0.1069
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.014 0.1056 0.1176
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0205 0.1663 0.1883
Schistosoma mansoni hypothetical protein 0.0113 0.0811 0.0897
Trichomonas vaginalis TKL family protein kinase 0.0213 0.1733 0.1554
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0625 0.5544 1
Entamoeba histolytica protein kinase domain containing protein 0.0213 0.1733 0.3186
Echinococcus granulosus Niemann Pick C1 protein 0.016 0.125 0.1415
Schistosoma mansoni protein kinase 0.0213 0.1733 0.1944
Echinococcus multilocularis kinase suppressor of Ras 1 0.0213 0.1733 0.1962
Schistosoma mansoni nck2/grb4 0.0317 0.2693 0.3033
Loa Loa (eye worm) hypothetical protein 0.0058 0.0302 0.0336
Trichomonas vaginalis TKL family protein kinase 0.0213 0.1733 0.1554
Brugia malayi SH2 domain containing protein 0.0529 0.466 0.5321
Schistosoma mansoni protein kinase 0.0213 0.1733 0.1944
Brugia malayi Variant SH3 domain containing protein 0.0317 0.2693 0.3075
Loa Loa (eye worm) hypothetical protein 0.0048 0.0212 0.0233
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0091 0.0606 0.1544
Schistosoma mansoni hypothetical protein 0.0046 0.0196 0.02
Echinococcus multilocularis tyrosine protein kinase Abl 0.0529 0.466 0.5276
Echinococcus granulosus kinase suppressor of Ras 1 0.0213 0.1733 0.1962
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0213 0.1733 0.3186
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0117 0.0845 0.1314
Loa Loa (eye worm) TK/CSK protein kinase 0.0213 0.1733 0.1972
Echinococcus granulosus tyrosine protein kinase 0.0213 0.1733 0.1962
Schistosoma mansoni ap endonuclease 0.0106 0.0749 0.0828
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0317 0.2693 0.3069
Trypanosoma cruzi glucose-6-phosphate 1-dehydrogenase, putative 0.056 0.4941 0.8885
Brugia malayi Sex muscle abnormal protein 5 0.0317 0.2693 0.3075
Echinococcus granulosus activated cdc42 kinase 1 0.0213 0.1733 0.1962
Loa Loa (eye worm) cytochrome P450 0.0075 0.0461 0.0518
Echinococcus multilocularis tyrosine protein kinase pr2 0.0213 0.1733 0.1962
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0058 0.0302 0.032
Echinococcus multilocularis snurportin 1 0.0241 0.1997 0.2261
Entamoeba histolytica protein kinase domain containing protein 0.0213 0.1733 0.3186
Loa Loa (eye worm) hypothetical protein 0.0213 0.1733 0.1972
Loa Loa (eye worm) hypothetical protein 0.0036 0.0102 0.0108
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0042 0.0151 0.0031
Leishmania major 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0117 0.0845 0.1314
Echinococcus multilocularis signal transduction protein lnk realted 0.0317 0.2693 0.3049
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0106 0.0749 0.0895
Trichomonas vaginalis TKL family protein kinase 0.0213 0.1733 0.1554
Schistosoma mansoni tyrosine protein kinase 0.0213 0.1733 0.1944
Onchocerca volvulus 0.0317 0.2693 0.2693
Trichomonas vaginalis TKL family protein kinase 0.0213 0.1733 0.1554
Echinococcus multilocularis Niemann Pick C1 protein 0.0112 0.0804 0.0911
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0213 0.1733 0.2955
Echinococcus multilocularis tyrosine kinase 0.0213 0.1733 0.1962
Brugia malayi Protein kinase domain containing protein 0.0213 0.1733 0.1979
Trypanosoma cruzi glucose-6-phosphate 1-dehydrogenase, putative 0.0185 0.1481 0.2489
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0374 0.0442
Brugia malayi Protein kinase domain containing protein 0.0213 0.1733 0.1979
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0464 0.4056 0.4632
Echinococcus granulosus expressed conserved protein 0.0105 0.0741 0.0839
Giardia lamblia Kinase, NEK 0.0213 0.1733 0.2347
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0042 0.0151 0.0031
Entamoeba histolytica protein kinase domain containing protein 0.0213 0.1733 0.3186
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0034 0.0077 0.0065
Brugia malayi hypothetical protein 0.0529 0.466 0.5321
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0317 0.2693 0.3069
Entamoeba histolytica protein kinase, putative 0.0213 0.1733 0.3186
Schistosoma mansoni aldehyde dehydrogenase 0.0142 0.108 0.1203
Plasmodium vivax ataxin-2 like protein, putative 0.0042 0.015 0.0098
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0034 0.0077 0.0088
Trypanosoma cruzi PAB1-binding protein , putative 0.0042 0.015 0.0029
Echinococcus multilocularis protein KINase family member (kin 25) 0.0213 0.1733 0.1962
Entamoeba histolytica tyrosine kinase, putative 0.0213 0.1733 0.3186
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0075 0.0461 0.0933
Trichomonas vaginalis TKL family protein kinase 0.0213 0.1733 0.1554
Loa Loa (eye worm) STAT protein 0.0317 0.2693 0.3069
Loa Loa (eye worm) hypothetical protein 0.0113 0.0811 0.0917
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0213 0.1733 0.1972
Echinococcus granulosus tyrosine protein kinase Fyn 0.0529 0.466 0.5276
Schistosoma mansoni hypothetical protein 0.0046 0.0196 0.02
Entamoeba histolytica tyrosine kinase, putative 0.0213 0.1733 0.3186
Brugia malayi Guanylyl cyclase protein 23 0.0213 0.1733 0.1979
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0075 0.0461 0.0933
Leishmania major hypothetical protein, conserved 0.0213 0.1733 0.2955
Trichomonas vaginalis TKL family protein kinase 0.0213 0.1733 0.1554
Loa Loa (eye worm) cytochrome P450 family protein 0.0101 0.0703 0.0794
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0106 0.0749 0.1136
Trichomonas vaginalis TKL family protein kinase 0.0213 0.1733 0.1554
Entamoeba histolytica tyrosine kinase, putative 0.0213 0.1733 0.3186
Echinococcus granulosus expressed conserved protein 0.0317 0.2693 0.3049
Entamoeba histolytica serine/threonine kinase, putative 0.0213 0.1733 0.3186
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.0317 0.2693 0.3069
Trichomonas vaginalis TKL family protein kinase 0.0213 0.1733 0.1554
Schistosoma mansoni protein kinase 0.0213 0.1733 0.1944
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0123 0.0906 0.1026
Loa Loa (eye worm) TK protein kinase 0.0213 0.1733 0.1972
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0213 0.1733 0.1972
Brugia malayi bone morphogenetic protein type 1 receptor 0.0213 0.1733 0.1979
Entamoeba histolytica hypothetical protein 0.0213 0.1733 0.3186
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0075 0.0461 0.0933
Schistosoma mansoni hypothetical protein 0.0044 0.0172 0.0173
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0034 0.0077 0.0088
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0034 0.0077 0.0079
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0464 0.4056 0.725
Brugia malayi nuclear hormone receptor 0.0034 0.0077 0.0088
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0066 0.0374 0.0423
Trichomonas vaginalis TKL family protein kinase 0.0213 0.1733 0.1554
Trichomonas vaginalis protein kinase atn1, putative 0.0213 0.1733 0.1554
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0357 0.3067 0.3496
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0213 0.1733 0.3186
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0042 0.0151 0.0101
Plasmodium falciparum glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase 0.056 0.4941 1
Schistosoma mansoni serine/threonine RGC 0.0213 0.1733 0.1944
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0058 0.0302 0.0549
Schistosoma mansoni carbonic anhydrase-related 0.0218 0.1782 0.1999
Schistosoma mansoni aryl hydrocarbon receptor 0.0034 0.0082 0.0071
Loa Loa (eye worm) steroid hormone receptor 0.0034 0.0077 0.0079
Leishmania major cathepsin L-like protease 0.0053 0.0258 0.0228
Trichomonas vaginalis TKL family protein kinase 0.0213 0.1733 0.1554
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0213 0.1733 0.1554
Toxoplasma gondii hypothetical protein 0.0218 0.1782 0.3427
Echinococcus multilocularis carbonic anhydrase 0.0218 0.1782 0.2017
Schistosoma mansoni tyrosine kinase 0.0529 0.466 0.5265
Loa Loa (eye worm) abnormal epIthelia family member 0.0027 0.002 0.0013
Loa Loa (eye worm) hypothetical protein 0.0317 0.2693 0.3069
Loa Loa (eye worm) CYP4Cod1 0.0101 0.0703 0.0794
Trichomonas vaginalis TKL family protein kinase 0.0213 0.1733 0.1554
Brugia malayi photoreceptor-specific nuclear receptor 0.0034 0.0077 0.0088
Brugia malayi RNA, U transporter 1 0.0064 0.0361 0.0412
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0034 0.0077 0.0088
Brugia malayi SH2 domain containing protein 0.0317 0.2693 0.3075
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0034 0.0077 0.0079
Loa Loa (eye worm) TK/FER protein kinase 0.0529 0.466 0.5317
Schistosoma mansoni tyrosine kinase 0.0213 0.1733 0.1944
Loa Loa (eye worm) TK/FER protein kinase 0.0213 0.1733 0.1972
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0034 0.0077 0.0088
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0042 0.0151 0.0054
Entamoeba histolytica hypothetical protein 0.0213 0.1733 0.3186
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0213 0.1733 0.1979
Loa Loa (eye worm) hypothetical protein 0.0218 0.1782 0.2027
Trypanosoma cruzi hypothetical protein, conserved 0.0058 0.0302 0.031
Brugia malayi Immunoglobulin I-set domain containing protein 0.0213 0.1733 0.1979
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0034 0.0077 0.0088
Echinococcus multilocularis lipoxygenase domain containing protein 0.0036 0.0102 0.0116
Trichomonas vaginalis TKL family protein kinase 0.0213 0.1733 0.1554
Schistosoma mansoni protein tyrosine kinase 0.0213 0.1733 0.1944
Brugia malayi Receptor family ligand binding region containing protein 0.0213 0.1733 0.1979
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0049 0.0215 0.0149
Loa Loa (eye worm) hypothetical protein 0.0244 0.2022 0.2302
Trichomonas vaginalis TKL family protein kinase 0.0213 0.1733 0.1554
Entamoeba histolytica protein kinase domain containing protein 0.0213 0.1733 0.3186
Brugia malayi SRC-1 0.0529 0.466 0.5321
Brugia malayi RNA binding protein 0.0123 0.0906 0.1034
Echinococcus granulosus tyrosine protein kinase ABL1 0.0529 0.466 0.5276
Plasmodium falciparum carbonic anhydrase 0.0218 0.1782 0.3471
Schistosoma mansoni rab6-interacting 0.0036 0.0102 0.0094
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0075 0.0461 0.1069
Brugia malayi MH2 domain containing protein 0.0107 0.0755 0.0862
Schistosoma mansoni hypothetical protein 0.0241 0.1997 0.2244
Onchocerca volvulus 0.0213 0.1733 0.1733
Loa Loa (eye worm) SRC-1 0.0529 0.466 0.5317
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0317 0.2693 0.3049
Trichomonas vaginalis TKL family protein kinase 0.0213 0.1733 0.1554
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0529 0.466 0.5276
Brugia malayi Protein kinase domain containing protein 0.0213 0.1733 0.1979
Toxoplasma gondii aldehyde dehydrogenase 0.0142 0.108 0.1968
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0317 0.2693 0.3069
Echinococcus granulosus insulin receptor 0.0213 0.1733 0.1962
Echinococcus multilocularis sterol regulatory element binding protein 0.0048 0.0212 0.024
Echinococcus multilocularis carbonic anhydrase 0.0218 0.1782 0.2017
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0317 0.2693 0.3033
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0075 0.0461 0.0933
Echinococcus granulosus ecdysone induced protein 78C 0.0034 0.0077 0.0088
Entamoeba histolytica hypothetical protein 0.0213 0.1733 0.3186
Schistosoma mansoni growth factor receptor-bound protein 0.0317 0.2693 0.3033
Entamoeba histolytica serine/threonine kinase, putative 0.0213 0.1733 0.3186
Schistosoma mansoni tensin-related 0.0317 0.2693 0.3033
Trichomonas vaginalis TKL family protein kinase 0.0213 0.1733 0.1554
Loa Loa (eye worm) hypothetical protein 0.0317 0.2693 0.3069
Echinococcus granulosus ephrin type A receptor 4 A 0.0213 0.1733 0.1962
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0106 0.0749 0.5
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0529 0.466 0.5276
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0213 0.1733 0.1972
Echinococcus granulosus neuropeptide receptor A26 0.0397 0.3432 0.3886
Echinococcus granulosus tyrosine protein kinase pr2 0.0213 0.1733 0.1962
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0075 0.0461 0.0604
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0529 0.466 0.5276
Schistosoma mansoni growth factor receptor-bound protein 0.0317 0.2693 0.3033
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0114 0.082 0.0908
Schistosoma mansoni tar DNA-binding protein 0.0123 0.0906 0.1005
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0213 0.1733 0.1962
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0625 0.5544 0.633
Toxoplasma gondii cytochrome p450 superfamily protein 0.0075 0.0461 0.068
Echinococcus multilocularis ephrin type A receptor 4 A 0.0213 0.1733 0.1962
Schistosoma mansoni tensin 0.0317 0.2693 0.3033
Loa Loa (eye worm) TK/FER protein kinase 0.0529 0.466 0.5317
Onchocerca volvulus 0.0036 0.0102 0.0102
Entamoeba histolytica tyrosine kinase, putative 0.0213 0.1733 0.3186
Schistosoma mansoni SH2A 0.0317 0.2693 0.3033
Schistosoma mansoni tyrosine kinase 0.0529 0.466 0.5265
Brugia malayi Cytochrome P450 family protein 0.0127 0.0936 0.1069
Brugia malayi Pre-SET motif family protein 0.0973 0.8758 1
Loa Loa (eye worm) TK/FER protein kinase 0.0529 0.466 0.5317
Echinococcus granulosus signal transduction protein lnk realted 0.0317 0.2693 0.3049
Echinococcus granulosus N chimaerin 0.0317 0.2693 0.3049
Loa Loa (eye worm) hypothetical protein 0.0604 0.5349 0.6104
Echinococcus multilocularis raf serine:threonine protein kinase 0.0213 0.1733 0.1962
Plasmodium falciparum protein kinase, putative 0.0213 0.1733 0.337
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0213 0.1733 0.1962
Loa Loa (eye worm) hypothetical protein 0.0319 0.2719 0.3099
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0213 0.1733 0.1962
Brugia malayi Protein kinase domain containing protein 0.0213 0.1733 0.1979
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0075 0.0461 0.1069
Echinococcus multilocularis tensin 0.0317 0.2693 0.3049
Mycobacterium tuberculosis Conserved protein 0.0058 0.0302 0.0549
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0205 0.1663 0.1865
Brugia malayi Protein kinase domain containing protein 0.0213 0.1733 0.1979
Trichomonas vaginalis conserved hypothetical protein 0.0213 0.1733 0.1554
Schistosoma mansoni tyrosine kinase 0.0213 0.1733 0.1944
Entamoeba histolytica tyrosine kinase, putative 0.0213 0.1733 0.3186
Echinococcus multilocularis growth factor receptor bound protein 2 0.0317 0.2693 0.3049
Trichomonas vaginalis set domain proteins, putative 0.1107 1 1
Entamoeba histolytica protein kinase, putative 0.0317 0.2693 0.5421
Trichomonas vaginalis TKL family protein kinase 0.0213 0.1733 0.1554
Trypanosoma brucei Pseudokinase, putative 0.0213 0.1733 0.2955
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0464 0.4056 0.4632
Trichomonas vaginalis TKL family protein kinase 0.0213 0.1733 0.1554
Onchocerca volvulus 0.0529 0.466 0.466
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0213 0.1733 0.1979
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0112 0.0804 0.1023
Echinococcus multilocularis 0.0075 0.0461 0.0522
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0101 0.07 0.185
Loa Loa (eye worm) hypothetical protein 0.0058 0.0302 0.0336
Brugia malayi beta-lactamase 0.0058 0.0302 0.0345
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0213 0.1733 0.1962
Schistosoma mansoni tyrosine kinase 0.0213 0.1733 0.1944
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0529 0.466 1
Mycobacterium ulcerans glucose-6-phosphate 1-dehydrogenase 0.0366 0.3146 0.6367
Loa Loa (eye worm) TK protein kinase 0.0213 0.1733 0.1972
Entamoeba histolytica ankyrin repeat protein 0.0213 0.1733 0.3186
Entamoeba histolytica tyrosine kinase, putative 0.0213 0.1733 0.3186
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.056 0.4941 0.4831
Schistosoma mansoni GTPase activating protein 0.0317 0.2693 0.3033
Schistosoma mansoni nuclear hormone receptor 0.0034 0.0077 0.0065
Echinococcus granulosus microtubule associated protein 2 0.0541 0.4767 0.5397
Entamoeba histolytica ankyrin repeat protein 0.0213 0.1733 0.3186
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0042 0.0151 0.0171
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0053 0.0258 0.0228
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0213 0.1733 0.3186
Loa Loa (eye worm) TK/FER protein kinase 0.0213 0.1733 0.1972
Loa Loa (eye worm) hypothetical protein 0.0042 0.015 0.0162
Loa Loa (eye worm) TK protein kinase 0.0213 0.1733 0.1972
Brugia malayi SH2 domain containing protein 0.0604 0.5349 0.6108
Brugia malayi laminin-like protein K08C7.3 precursor 0.0027 0.002 0.0023
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0213 0.1733 0.1962
Plasmodium falciparum tyrosine kinase-like protein 0.0213 0.1733 0.337
Loa Loa (eye worm) hypoxia-induced factor 1 0.0106 0.0744 0.0841
Loa Loa (eye worm) hypothetical protein 0.0213 0.1733 0.1972
Brugia malayi Protein kinase domain containing protein 0.0213 0.1733 0.1979
Brugia malayi protein-tyrosine kinase 0.0529 0.466 0.5321
Echinococcus multilocularis transcription factor Dp 1 0.0038 0.0118 0.0133
Treponema pallidum glucose-6-phosphate 1-dehydrogenase 0.056 0.4941 1
Entamoeba histolytica protein kinase, putative 0.0213 0.1733 0.3186
Schistosoma mansoni protein kinase 0.0213 0.1733 0.1944
Loa Loa (eye worm) hypothetical protein 0.0317 0.2693 0.3069
Brugia malayi latrophilin 2 splice variant baaae 0.0244 0.2022 0.2309
Brugia malayi SH2 domain containing protein 0.0317 0.2693 0.3075
Schistosoma mansoni lipoxygenase 0.0218 0.1777 0.1994
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0034 0.0077 0.0079
Trichomonas vaginalis ap endonuclease, putative 0.0106 0.0749 0.0549
Loa Loa (eye worm) hypothetical protein 0.0034 0.0077 0.0079
Entamoeba histolytica hypothetical protein 0.0213 0.1733 0.3186
Loa Loa (eye worm) TK protein kinase 0.0213 0.1733 0.1972
Brugia malayi Variant SH3 domain containing protein 0.0317 0.2693 0.3075
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0053 0.0258 0.0228
Echinococcus multilocularis Polycystic kidney disease protein 0.0036 0.0102 0.0116
Onchocerca volvulus 0.0213 0.1733 0.1733
Loa Loa (eye worm) doublecortin family protein 0.0036 0.0102 0.0108
Loa Loa (eye worm) hypothetical protein 0.0034 0.0077 0.0079
Echinococcus multilocularis protein patched 0.0048 0.0212 0.024
Echinococcus granulosus beta LACTamase domain containing family member 0.0058 0.0302 0.0342
Trypanosoma cruzi cytochrome P450, putative 0.0101 0.0703 0.1051
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0213 0.1733 0.1972
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0075 0.0461 0.1069
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0213 0.1733 0.1962
Echinococcus granulosus tyrosine protein kinase shark 0.0529 0.466 0.5276
Echinococcus granulosus epidermal growth factor receptor 0.0213 0.1733 0.1962
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0066 0.0374 0.0427
Echinococcus multilocularis tar DNA binding protein 0.0123 0.0906 0.1025
Entamoeba histolytica protein kinase domain containing protein 0.0213 0.1733 0.3186
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0213 0.1733 0.3186
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0213 0.1733 0.1979
Trichomonas vaginalis TKL family protein kinase 0.0213 0.1733 0.1554
Schistosoma mansoni tar DNA-binding protein 0.0123 0.0906 0.1005
Trichomonas vaginalis TKL family protein kinase 0.0213 0.1733 0.1554
Mycobacterium ulcerans aldehyde dehydrogenase 0.0142 0.108 0.2187
Schistosoma mansoni tyrosine kinase 0.0213 0.1733 0.1944
Plasmodium vivax tyrosine kinase-like protein, putative 0.0213 0.1733 0.337
Trichomonas vaginalis TKL family protein kinase 0.0213 0.1733 0.1554
Onchocerca volvulus 0.0317 0.2693 0.2693
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0142 0.108 0.1223
Entamoeba histolytica protein kinase, putative 0.0213 0.1733 0.3186
Brugia malayi hypothetical protein 0.0317 0.2693 0.3075
Brugia malayi Protein kinase domain containing protein 0.0213 0.1733 0.1979
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0529 0.466 0.5276
Brugia malayi Protein kinase domain containing protein 0.0213 0.1733 0.1979
Brugia malayi Tensin 0.0317 0.2693 0.3075
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.014 0.1056 0.1196
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0205 0.1663 0.1865
Echinococcus multilocularis SH2 motif 0.0317 0.2693 0.3049
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0042 0.0151 0.0031
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0034 0.0077 0.0088
Echinococcus multilocularis tensin 0.0317 0.2693 0.3049
Schistosoma mansoni tyrosine kinase 0.0213 0.1733 0.1944
Trichomonas vaginalis penicillin-binding protein, putative 0.0058 0.0302 0.0093
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0529 0.466 0.5276
Trichomonas vaginalis esterase, putative 0.0058 0.0302 0.0093
Loa Loa (eye worm) TK/EGFR protein kinase 0.0213 0.1733 0.1972
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0075 0.0461 0.0933
Brugia malayi Isocitrate dehydrogenase 0.0042 0.0151 0.0172
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0218 0.1782 0.2034
Entamoeba histolytica tyrosine kinase, putative 0.0213 0.1733 0.3186
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0034 0.0077 0.0077
Trichomonas vaginalis TKL family protein kinase 0.0213 0.1733 0.1554
Echinococcus granulosus carbonic anhydrase 0.0218 0.1782 0.2017
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0213 0.1733 0.1733
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0213 0.1733 0.2955
Loa Loa (eye worm) hypothetical protein 0.0213 0.1733 0.1972
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0213 0.1733 0.1962
Brugia malayi Thrombospondin N-terminal -like domain containing protein 0.0027 0.002 0.0023
Entamoeba histolytica protein kinase, putative 0.0213 0.1733 0.3186
Schistosoma mansoni suppressor of cytokine signaling 0.0317 0.2693 0.3033
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0317 0.2693 0.3049
Schistosoma mansoni transcription factor LCR-F1 0.0098 0.0673 0.0741
Echinococcus multilocularis neuropeptide s receptor 0.0397 0.3432 0.3886
Onchocerca volvulus Protein ultraspiracle homolog 0.0034 0.0077 0.0077
Brugia malayi glutathione reductase 0.004 0.0135 0.0154
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0034 0.0077 0.0088
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0101 0.07 1
Schistosoma mansoni RAR-like nuclear receptor 0.0034 0.0077 0.0065
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0066 0.0374 0.0021
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0529 0.466 0.5276
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0218 0.1782 0.2034
Entamoeba histolytica tyrosine kinase, putative 0.0213 0.1733 0.3186
Schistosoma mansoni suppressor of cytokine signaling 0.0317 0.2693 0.3033
Brugia malayi hypothetical protein 0.0036 0.0102 0.0117
Echinococcus multilocularis glucose 6 phosphate 1 dehydrogenase 0.056 0.4941 0.5594
Trichomonas vaginalis conserved hypothetical protein 0.0213 0.1733 0.1554
Echinococcus granulosus GPCR family 2 0.0113 0.0811 0.0918
Mycobacterium leprae Conserved hypothetical protein 0.0075 0.0461 0.3994
Echinococcus granulosus SH2 domain containing adapter protein F 0.0317 0.2693 0.3049
Echinococcus granulosus tyrosine protein kinase Src42A 0.0317 0.2693 0.3049
Trichomonas vaginalis TKL family protein kinase 0.0213 0.1733 0.1554
Echinococcus multilocularis tyrosine protein kinase shark 0.0529 0.466 0.5276
Toxoplasma gondii LsmAD domain-containing protein 0.0042 0.015 0.0032
Mycobacterium ulcerans lipase LipD 0.0058 0.0302 0.0612
Giardia lamblia Kinase, NEK 0.0213 0.1733 0.2347
Echinococcus granulosus tyrosine protein kinase Srms 0.0529 0.466 0.5276
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0213 0.1733 0.3326
Loa Loa (eye worm) thioredoxin reductase 0.004 0.0135 0.0145
Brugia malayi follicle stimulating hormone receptor 0.0469 0.4103 0.4685
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0075 0.0461 0.1069
Schistosoma mansoni tyrosine kinase 0.0529 0.466 0.5265
Brugia malayi hypothetical protein 0.0036 0.0102 0.0117
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0113 0.0811 0.0918
Loa Loa (eye worm) carbonic anhydrase 3 0.0464 0.4056 0.4627
Loa Loa (eye worm) RNA binding protein 0.0123 0.0906 0.1026
Trichomonas vaginalis TKL family protein kinase 0.0213 0.1733 0.1554
Trichomonas vaginalis TKL family protein kinase 0.0213 0.1733 0.1554
Brugia malayi STAT protein, DNA binding domain containing protein 0.0317 0.2693 0.3075
Trichomonas vaginalis TKL family protein kinase 0.0213 0.1733 0.1554
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0053 0.0258 0.0228
Loa Loa (eye worm) protein kinase domain-containing protein 0.0213 0.1733 0.1972
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0213 0.1733 0.1962
Brugia malayi Raf kinase 0.0213 0.1733 0.1979
Loa Loa (eye worm) latrophilin receptor protein 2 0.0113 0.0811 0.0917
Entamoeba histolytica receptor protein kinase, putative 0.0213 0.1733 0.3186
Loa Loa (eye worm) TK protein kinase 0.0213 0.1733 0.1972
Trypanosoma cruzi cytochrome P450, putative 0.0101 0.0703 0.1051
Plasmodium vivax tyrosine kinase-like protein, putative 0.0213 0.1733 0.337
Echinococcus multilocularis SH2 motif 0.0317 0.2693 0.3049
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0213 0.1733 0.1944
Brugia malayi Protein kinase domain containing protein 0.0213 0.1733 0.1979
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0213 0.1733 0.1554
Brugia malayi Calcitonin receptor-like protein seb-1 0.0357 0.3067 0.3502
Echinococcus multilocularis FTZ F1 alpha 0.0034 0.0077 0.0088
Echinococcus multilocularis tyrosine protein kinase csk 0.0213 0.1733 0.1962
Trypanosoma cruzi cruzipain precursor, putative 0.0053 0.0258 0.0228
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0529 0.466 0.5276
Brugia malayi Protein kinase domain containing protein 0.0213 0.1733 0.1979
Trypanosoma brucei hypothetical protein, conserved 0.0058 0.0302 0.031
Brugia malayi hypoxia-induced factor 1 0.0106 0.0744 0.0849
Brugia malayi hypothetical protein 0.0213 0.1733 0.1979
Echinococcus multilocularis FL cytokine receptor 0.0213 0.1733 0.1962
Schistosoma mansoni polycystin 1-related 0.0036 0.0102 0.0094
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0317 0.2693 0.3049
Leishmania major C-8 sterol isomerase-like protein 0.0625 0.5544 1
Loa Loa (eye worm) TK protein kinase 0.0213 0.1733 0.1972
Echinococcus multilocularis isocitrate dehydrogenase 0.0042 0.0151 0.0171
Brugia malayi Doublecortin family protein 0.0036 0.0102 0.0117
Echinococcus granulosus activin receptor type 0.0213 0.1733 0.1962
Echinococcus granulosus tyrosine protein kinase Src64B 0.0529 0.466 0.5276
Loa Loa (eye worm) RGC/RGC protein kinase 0.0213 0.1733 0.1972
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0213 0.1733 0.3326
Entamoeba histolytica protein kinase, putative 0.0213 0.1733 0.3186
Echinococcus multilocularis tyrosine protein kinase csk 0.0213 0.1733 0.1962
Trichomonas vaginalis TKL family protein kinase 0.0213 0.1733 0.1554
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0101 0.07 0.185
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0106 0.0749 0.1516
Plasmodium vivax protein kinase, putative 0.0213 0.1733 0.337
Echinococcus multilocularis integrin linked protein kinase 0.0213 0.1733 0.1962
Schistosoma mansoni tyrosine kinase 0.0529 0.466 0.5265
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0213 0.1733 0.1972
Brugia malayi TAR-binding protein 0.0123 0.0906 0.1034
Loa Loa (eye worm) TK/FAK protein kinase 0.0213 0.1733 0.1972
Trichomonas vaginalis TKL family protein kinase 0.0213 0.1733 0.1554
Leishmania major cytochrome p450-like protein 0.0101 0.0703 0.1051
Brugia malayi SH2 domain containing protein 0.0317 0.2693 0.3075
Entamoeba histolytica protein kinase domain containing protein 0.0213 0.1733 0.3186
Schistosoma mansoni hypothetical protein 0.0317 0.2693 0.3033
Trichomonas vaginalis TKL family protein kinase 0.0213 0.1733 0.1554
Entamoeba histolytica hypothetical protein, conserved 0.0213 0.1733 0.3186
Schistosoma mansoni tyrosine kinase 0.0213 0.1733 0.1944
Schistosoma mansoni glucose-6-phosphate 1-dehydrogenase 0.056 0.4941 0.5584
Entamoeba histolytica tyrosine kinase, putative 0.0213 0.1733 0.3186
Entamoeba histolytica hypothetical protein 0.0213 0.1733 0.3186
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0213 0.1733 0.3186
Loa Loa (eye worm) hypothetical protein 0.0058 0.0302 0.0336
Brugia malayi Protein kinase domain containing protein 0.0213 0.1733 0.1979
Echinococcus multilocularis microtubule associated protein 2 0.0541 0.4767 0.5397
Loa Loa (eye worm) hypothetical protein 0.0027 0.002 0.0013
Schistosoma mansoni serine/threonine protein kinase 0.0213 0.1733 0.1944
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0034 0.0077 0.0079
Entamoeba histolytica tyrosin kinase, putative 0.0213 0.1733 0.3186
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0205 0.1663 0.1899
Onchocerca volvulus 0.0317 0.2693 0.2693
Brugia malayi Protein kinase domain containing protein 0.0213 0.1733 0.1979
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0529 0.466 0.5276
Trichomonas vaginalis TKL family protein kinase 0.0213 0.1733 0.1554
Echinococcus multilocularis protein kinase 0.0213 0.1733 0.1962
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0091 0.0606 0.1544
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0213 0.1733 0.1962
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0213 0.1733 0.3186
Schistosoma mansoni vav2 0.0317 0.2693 0.3033
Onchocerca volvulus 0.0317 0.2693 0.2693
Schistosoma mansoni hypothetical protein 0.0113 0.0811 0.0897
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0317 0.2693 0.3033
Entamoeba histolytica tyrosine kinase, putative 0.0213 0.1733 0.3186
Entamoeba histolytica protein kinase, putative 0.0213 0.1733 0.3186
Loa Loa (eye worm) RGC/RGC protein kinase 0.0213 0.1733 0.1972
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0075 0.0461 0.0933
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0213 0.1733 0.1962
Loa Loa (eye worm) hypothetical protein 0.0218 0.1782 0.2027
Schistosoma mansoni serine/threonine protein kinase 0.0213 0.1733 0.1944
Loa Loa (eye worm) glucose-6-phosphate dehydrogenase 0.056 0.4941 0.5637
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0034 0.0077 0.0088
Trichomonas vaginalis TKL family protein kinase 0.0213 0.1733 0.1554
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0034 0.0077 0.0088
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0053 0.0258 0.0228
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0213 0.1733 0.1554
Entamoeba histolytica protein kinase, putative 0.0213 0.1733 0.3186
Trichomonas vaginalis TKL family protein kinase 0.0213 0.1733 0.1554
Onchocerca volvulus 0.0036 0.0102 0.0102
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0075 0.0461 0.1069
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0387 0.334 0.3781
Echinococcus granulosus c src tyrosine kinase 0.0529 0.466 0.5276
Schistosoma mansoni tensin-related 0.0317 0.2693 0.3033
Schistosoma mansoni tyrosine kinase 0.0213 0.1733 0.1944
Echinococcus granulosus retinal guanylyl cyclase 2 0.0213 0.1733 0.1962
Entamoeba histolytica protein kinase domain containing protein 0.0213 0.1733 0.3186
Schistosoma mansoni carbonic anhydrase 0.0218 0.1782 0.1999
Echinococcus granulosus pikachurin 0.0027 0.002 0.0022
Onchocerca volvulus 0.0529 0.466 0.466
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0317 0.2693 0.3049
Schistosoma mansoni microtubule-associated protein tau 0.0541 0.4767 0.5387
Echinococcus multilocularis carbonic anhydrase II 0.0464 0.4056 0.4592
Echinococcus multilocularis neuropeptide receptor A26 0.0397 0.3432 0.3886
Loa Loa (eye worm) hypothetical protein 0.0213 0.1733 0.1972
Trichomonas vaginalis TKL family protein kinase 0.0213 0.1733 0.1554
Trichomonas vaginalis penicillin-binding protein, putative 0.0058 0.0302 0.0093
Brugia malayi Furin-like cysteine rich region family protein 0.0213 0.1733 0.1979
Onchocerca volvulus 0.0213 0.1733 0.1733
Chlamydia trachomatis glucose-6-phosphate 1-dehydrogenase 0.056 0.4941 0.5
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0075 0.0461 0.0604
Echinococcus granulosus carbonic anhydrase 0.0218 0.1782 0.2017
Schistosoma mansoni hypothetical protein 0.0046 0.0196 0.02
Echinococcus granulosus natriuretic peptide receptor 1 0.0213 0.1733 0.1962
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0075 0.0461 0.0933
Entamoeba histolytica tyrosine kinase, putative 0.0213 0.1733 0.3186
Trichomonas vaginalis TKL family protein kinase 0.0213 0.1733 0.1554
Echinococcus multilocularis tyrosine protein kinase HCK 0.0213 0.1733 0.1962
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0053 0.0258 0.0228
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0241 0.1997 0.2273
Trichomonas vaginalis TKL family protein kinase 0.0213 0.1733 0.1554
Echinococcus granulosus hypothetical protein 0.0317 0.2693 0.3049
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0213 0.1733 0.1962
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0213 0.1733 0.1944
Echinococcus granulosus Polycystic kidney disease protein 0.0036 0.0102 0.0116
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0075 0.0461 0.1069
Loa Loa (eye worm) hypothetical protein 0.0317 0.2693 0.3069
Schistosoma mansoni coup transcription factor 0.0034 0.0077 0.0065
Mycobacterium tuberculosis Probable glucose-6-phosphate 1-dehydrogenase Zwf2 (G6PD) 0.0194 0.1561 0.4668
Echinococcus granulosus protein kinase 0.0213 0.1733 0.1962
Schistosoma mansoni hypothetical protein 0.007 0.0413 0.0446
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0213 0.1733 0.1733
Brugia malayi isocitrate dehydrogenase 0.0042 0.0151 0.0172
Loa Loa (eye worm) hypothetical protein 0.0317 0.2693 0.3069
Leishmania major cathepsin L-like protease 0.0053 0.0258 0.0228
Schistosoma mansoni tyrosine kinase 0.0213 0.1733 0.1944
Brugia malayi Protein kinase domain containing protein 0.0213 0.1733 0.1979
Trichomonas vaginalis TKL family protein kinase 0.0213 0.1733 0.1554
Entamoeba histolytica serine/threonine kinase, putative 0.0213 0.1733 0.3186
Loa Loa (eye worm) MH2 domain-containing protein 0.0107 0.0755 0.0853
Entamoeba histolytica protein kinase domain containing protein 0.0213 0.1733 0.3186
Toxoplasma gondii isocitrate dehydrogenase 0.0042 0.0151 0.0034
Brugia malayi glucose-6-phosphate dehydrogenase 0.056 0.4941 0.5641
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0142 0.108 0.1223
Trichomonas vaginalis STE family protein kinase 0.0213 0.1733 0.1554
Loa Loa (eye worm) TK/FER protein kinase 0.0213 0.1733 0.1972
Mycobacterium tuberculosis Probable lipase LipE 0.0058 0.0302 0.0549
Plasmodium vivax glucose-6-phosphate 1-dehydrogenase, putative 0.056 0.4941 1
Schistosoma mansoni tyrosine kinase 0.0213 0.1733 0.1944
Giardia lamblia Kinase 0.0213 0.1733 0.2347
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0387 0.334 0.3781
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0213 0.1733 0.1962
Plasmodium vivax thioredoxin reductase, putative 0.004 0.0135 0.0066
Echinococcus multilocularis protein tyrosine kinase 0.0213 0.1733 0.1962
Loa Loa (eye worm) hypothetical protein 0.0218 0.1782 0.2027
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.014 0.1056 0.1176
Entamoeba histolytica protein kinase domain containing protein 0.0213 0.1733 0.3186
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0213 0.1733 0.2955
Schistosoma mansoni hypothetical protein 0.0113 0.0811 0.0897
Echinococcus granulosus activated cdc42 kinase 1 0.0213 0.1733 0.1962
Echinococcus multilocularis tyrosine protein kinase csk 0.0213 0.1733 0.1962
Echinococcus granulosus tyrosine protein kinase Blk 0.0529 0.466 0.5276
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0106 0.0749 0.1337
Loa Loa (eye worm) serine/threonine protein kinase 0.0213 0.1733 0.1972
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0213 0.1733 0.3186
Brugia malayi Protein kinase domain containing protein 0.0213 0.1733 0.1979
Entamoeba histolytica hypothetical protein 0.0213 0.1733 0.3186
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0075 0.0461 0.0933
Brugia malayi Nuclear hormone receptor-like 1 0.0034 0.0077 0.0088
Brugia malayi EGF-like domain containing protein 0.0027 0.002 0.0023
Loa Loa (eye worm) hypothetical protein 0.014 0.1056 0.1198
Echinococcus granulosus lipoxygenase domain containing protein 0.0036 0.0102 0.0116
Loa Loa (eye worm) RGC/RGC protein kinase 0.0213 0.1733 0.1972
Toxoplasma gondii glucose-6-phosphate 1-dehydrogenase 0.056 0.4941 1
Plasmodium falciparum thioredoxin reductase 0.004 0.0135 0.0066
Echinococcus multilocularis activin receptor type 0.0213 0.1733 0.1962
Trichomonas vaginalis TKL family protein kinase 0.0213 0.1733 0.1554
Trichomonas vaginalis ap endonuclease, putative 0.0106 0.0749 0.0549
Schistosoma mansoni tyrosine kinase 0.0213 0.1733 0.1944
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0106 0.0749 0.1337
Brugia malayi Latrophilin receptor protein 2 0.0113 0.0811 0.0926
Loa Loa (eye worm) TAR-binding protein 0.0123 0.0906 0.1026
Trichomonas vaginalis TKL family protein kinase 0.0213 0.1733 0.1554
Entamoeba histolytica protein kinase, putative 0.0213 0.1733 0.3186
Echinococcus multilocularis tyrosine protein kinase csk 0.0213 0.1733 0.1962
Loa Loa (eye worm) hypothetical protein 0.0213 0.1733 0.1972
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0034 0.0077 0.0088
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0134 0.1009 0.1142
Schistosoma mansoni protein kinase 0.0213 0.1733 0.1944
Trypanosoma brucei Emopamil binding protein, putative 0.0117 0.0845 0.1314
Loa Loa (eye worm) hypothetical protein 0.0213 0.1733 0.1972
Loa Loa (eye worm) hypothetical protein 0.0115 0.0826 0.0934
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0034 0.0077 0.0065
Schistosoma mansoni tyrosine kinase 0.0529 0.466 0.5265
Echinococcus granulosus tyrosine kinase 0.0529 0.466 0.5276
Schistosoma mansoni tyrosine kinase 0.0213 0.1733 0.1944
Loa Loa (eye worm) TK/DDR protein kinase 0.0213 0.1733 0.1972
Brugia malayi Protein kinase domain containing protein 0.0213 0.1733 0.1979
Leishmania major glucose-6-phosphate 1-dehydrogenase, putative 0.056 0.4941 0.8885
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0113 0.0811 0.0918
Leishmania major hypothetical protein, conserved 0.0042 0.015 0.0029
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0213 0.1733 0.1962
Entamoeba histolytica tyrosine kinase, putative 0.0213 0.1733 0.3186
Schistosoma mansoni protein kinase 0.0213 0.1733 0.1944
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0034 0.0077 0.0088
Schistosoma mansoni tyrosine kinase 0.0213 0.1733 0.1944
Entamoeba histolytica protein kinase domain containing protein 0.0213 0.1733 0.3186
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0529 0.466 0.5276
Loa Loa (eye worm) hypothetical protein 0.0027 0.002 0.0013
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0317 0.2693 0.3069
Entamoeba histolytica serine/threonine kinase, putative 0.0213 0.1733 0.3186
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0075 0.0461 0.0604
Echinococcus granulosus sterol regulatory element binding protein 0.0048 0.0212 0.024
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.014 0.1056 0.1917
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0374 0.0442
Entamoeba histolytica tyrosine kinase, putative 0.0213 0.1733 0.3186
Loa Loa (eye worm) RGC/RGC protein kinase 0.0213 0.1733 0.1972
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0529 0.466 0.5265
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0042 0.0151 0.0031
Leishmania major hypothetical protein, conserved 0.0058 0.0302 0.031
Trypanosoma cruzi cysteine peptidase, putative 0.0053 0.0258 0.0228
Echinococcus multilocularis thyroid hormone receptor alpha 0.0034 0.0077 0.0088
Echinococcus granulosus carbonic anhydrase II 0.0464 0.4056 0.4592
Loa Loa (eye worm) TK protein kinase 0.0213 0.1733 0.1972
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0469 0.4103 0.468
Loa Loa (eye worm) TK/FER protein kinase 0.0213 0.1733 0.1972
Echinococcus granulosus tyrosine protein kinase csk 0.0213 0.1733 0.1962
Echinococcus multilocularis epidermal growth factor receptor 0.0213 0.1733 0.1962
Brugia malayi nuclear receptor NHR-88 0.0034 0.0077 0.0088
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0106 0.0749 0.1136
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0075 0.0461 0.1069
Echinococcus multilocularis transfer RNA-Thr 0.0213 0.1733 0.1962
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0213 0.1733 0.1962
Schistosoma mansoni serine/threonine protein kinase 0.0213 0.1733 0.1944
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0034 0.0077 0.0088
Echinococcus granulosus tyrosine protein kinase Fyn 0.0529 0.466 0.5276
Schistosoma mansoni tyrosine kinase 0.0213 0.1733 0.1944
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0374 0.0442
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0034 0.0077 0.0065
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0058 0.0302 0.0549
Plasmodium falciparum ataxin-2 like protein, putative 0.0042 0.015 0.0098
Trypanosoma brucei glucose-6-phosphate 1-dehydrogenase 0.056 0.4941 0.8885
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0075 0.0461 0.0933
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0075 0.0461 0.1069
Trichomonas vaginalis TKL family protein kinase 0.0213 0.1733 0.1554
Echinococcus granulosus RUN 0.0036 0.0102 0.0116
Echinococcus granulosus tyrosine protein kinase Lyn 0.0529 0.466 0.5276
Echinococcus multilocularis N chimaerin 0.0317 0.2693 0.3049
Trichomonas vaginalis conserved hypothetical protein 0.0213 0.1733 0.1554
Brugia malayi cytochrome P450 0.0075 0.0461 0.0527
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0075 0.0461 0.1069
Trichomonas vaginalis TKL family protein kinase 0.0213 0.1733 0.1554
Loa Loa (eye worm) hypothetical protein 0.0058 0.0302 0.0336
Trichomonas vaginalis D-aminoacylase, putative 0.0058 0.0302 0.0093
Brugia malayi ephrin receptor 1 precursor 0.0213 0.1733 0.1979
Entamoeba histolytica protein kinase, putative 0.0213 0.1733 0.3186
Loa Loa (eye worm) hypothetical protein 0.0625 0.5544 0.6327
Trichomonas vaginalis TKL family protein kinase 0.0213 0.1733 0.1554
Loa Loa (eye worm) hypothetical protein 0.0059 0.0312 0.0347
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0075 0.0461 0.0604
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.0317 0.2693 0.2693
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0213 0.1733 0.3186
Trichomonas vaginalis conserved hypothetical protein 0.0213 0.1733 0.1554
Toxoplasma gondii protein kinase domain-containing protein 0.0213 0.1733 0.3326
Loa Loa (eye worm) TK/RYK protein kinase 0.0213 0.1733 0.1972
Brugia malayi Protein kinase domain containing protein 0.0213 0.1733 0.1979
Mycobacterium tuberculosis Probable esterase LipL 0.0058 0.0302 0.0549
Loa Loa (eye worm) TK/FER protein kinase 0.0529 0.466 0.5317
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0053 0.0258 0.0228
Loa Loa (eye worm) hypothetical protein 0.0213 0.1733 0.1972
Echinococcus multilocularis epidermal growth factor receptor 0.0213 0.1733 0.1962
Schistosoma mansoni tyrosine kinase 0.0213 0.1733 0.1944
Echinococcus multilocularis protein kinase 0.0213 0.1733 0.1962
Brugia malayi Protein kinase domain containing protein 0.0529 0.466 0.5321
Brugia malayi Protein kinase domain containing protein 0.0213 0.1733 0.1979
Schistosoma mansoni tyrosine kinase 0.0213 0.1733 0.1944
Brugia malayi hypothetical protein 0.0213 0.1733 0.1979
Onchocerca volvulus 0.0034 0.0077 0.0077
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0034 0.0077 0.0079
Brugia malayi hypothetical protein 0.0098 0.0673 0.0769
Schistosoma mansoni shc transforming protein 0.0317 0.2693 0.3033
Entamoeba histolytica hypothetical protein 0.0098 0.0673 0.0718
Trichomonas vaginalis TKL family protein kinase 0.0213 0.1733 0.1554
Entamoeba histolytica hypothetical protein 0.0213 0.1733 0.3186
Trichomonas vaginalis TKL family protein kinase 0.0213 0.1733 0.1554
Brugia malayi Immunoglobulin I-set domain containing protein 0.0213 0.1733 0.1979
Loa Loa (eye worm) hypothetical protein 0.0034 0.0077 0.0079
Echinococcus granulosus transcription factor Dp 1 0.0038 0.0118 0.0133
Brugia malayi Pre-SET motif family protein 0.014 0.1056 0.1206
Leishmania major carbonic anhydrase-like protein 0.0464 0.4056 0.725
Echinococcus multilocularis lipoxygenase domain containing protein 0.0036 0.0102 0.0116
Brugia malayi tRNA modification GTPase TrmE family protein 0.0317 0.2693 0.3075
Echinococcus granulosus tensin 0.0317 0.2693 0.3049
Entamoeba histolytica tyrosine kinase, putative 0.0213 0.1733 0.3186
Echinococcus granulosus tyrosine kinase 0.0529 0.466 0.5276
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0034 0.0077 0.0088
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0075 0.0461 0.1069
Entamoeba histolytica tyrosine kinase, putative 0.0213 0.1733 0.3186
Trypanosoma cruzi Glucose-6-phosphate dehydrogenase, putative 0.018 0.1431 0.2397
Schistosoma mansoni protein kinase 0.0213 0.1733 0.1944
Echinococcus multilocularis SH2 domain containing protein 7 0.0317 0.2693 0.3049
Entamoeba histolytica protein kinase domain containing protein 0.0213 0.1733 0.3186
Echinococcus multilocularis c src tyrosine kinase 0.0529 0.466 0.5276
Mycobacterium tuberculosis Probable hydrolase 0.0058 0.0302 0.0549
Loa Loa (eye worm) TK protein kinase 0.0213 0.1733 0.1972
Toxoplasma gondii protein kinase 0.0213 0.1733 0.3326
Entamoeba histolytica protein kinase, putative 0.0213 0.1733 0.3186
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0058 0.0302 0.0345
Brugia malayi cytokine inducible SH2-containing protein 5 0.0317 0.2693 0.3075
Loa Loa (eye worm) hypothetical protein 0.0065 0.0365 0.0408
Brugia malayi integrin-linked kinase 0.0213 0.1733 0.1979
Schistosoma mansoni retinoic acid receptor RXR 0.0034 0.0077 0.0065
Loa Loa (eye worm) TK/FER protein kinase 0.0529 0.466 0.5317
Loa Loa (eye worm) TK/FER protein kinase 0.0529 0.466 0.5317
Echinococcus multilocularis slit 2 protein 0.0027 0.002 0.0022
Schistosoma mansoni tar DNA-binding protein 0.0123 0.0906 0.1005
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0042 0.0151 0.0031
Loa Loa (eye worm) hypothetical protein 0.0213 0.1733 0.1972
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0075 0.0461 0.1069
Trichomonas vaginalis 6-phosphogluconolactonase, putative 0.056 0.4941 0.4831
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0066 0.0374 0.0442
Loa Loa (eye worm) hypothetical protein 0.0317 0.2693 0.3069
Echinococcus granulosus snurportin 1 0.0241 0.1997 0.2261
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.014 0.1056 0.1196
Brugia malayi Protein kinase domain containing protein 0.0529 0.466 0.5321
Trichomonas vaginalis TKL family protein kinase 0.0213 0.1733 0.1554
Echinococcus granulosus cytochrome P450 2K1 0.0075 0.0461 0.0522
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0317 0.2693 0.3069
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0529 0.466 0.5276
Echinococcus granulosus FTZ F1 alpha 0.0034 0.0077 0.0088
Entamoeba histolytica protein kinase, putative 0.0213 0.1733 0.3186
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0529 0.466 0.5276
Mycobacterium leprae putative cytochrome p450 0.0075 0.0461 0.3994
Schistosoma mansoni ephrin receptor 0.0213 0.1733 0.1944
Echinococcus granulosus receptor type guanylyl cyclase 0.0213 0.1733 0.1962
Loa Loa (eye worm) hypothetical protein 0.0317 0.2693 0.3069
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0113 0.0811 0.0918
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0066 0.0374 0.0402
Onchocerca volvulus 0.0058 0.0302 0.0302
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0034 0.0077 0.0088
Echinococcus granulosus retinal guanylyl cyclase 2 0.0213 0.1733 0.1962
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0973 0.8758 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.014 0.1056 0.1176
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0034 0.0077 0.0079
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0317 0.2693 0.3033
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0034 0.0077 0.0065
Brugia malayi SH2 domain containing protein 0.0317 0.2693 0.3075
Trichomonas vaginalis CAMK family protein kinase 0.0213 0.1733 0.1554
Entamoeba histolytica protein kinase, putative 0.0213 0.1733 0.3186
Loa Loa (eye worm) hypothetical protein 0.0317 0.2693 0.3069
Onchocerca volvulus 0.0213 0.1733 0.1733
Schistosoma mansoni tyrosine kinase 0.0213 0.1733 0.1944
Entamoeba histolytica hypothetical protein 0.0213 0.1733 0.3186
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0213 0.1733 0.2955
Echinococcus multilocularis tyrosine kinase 0.0529 0.466 0.5276
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0317 0.2693 0.3049
Loa Loa (eye worm) TK/ABL protein kinase 0.0529 0.466 0.5317
Trichomonas vaginalis D-aminoacylase, putative 0.0058 0.0302 0.0093
Entamoeba histolytica hypothetical protein 0.0098 0.0673 0.0718
Entamoeba histolytica tyrosin kinase, putative 0.0213 0.1733 0.3186
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0042 0.0151 0.0171
Schistosoma mansoni hypothetical protein 0.0098 0.0673 0.0741
Plasmodium falciparum ataxin-2 like protein, putative 0.0042 0.015 0.0098
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0529 0.466 0.5276
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0075 0.0461 0.0933
Schistosoma mansoni tyrosine kinase 0.0213 0.1733 0.1944
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0464 0.4056 0.4627
Trichomonas vaginalis TKL family protein kinase 0.0213 0.1733 0.1554
Brugia malayi RNA recognition motif domain containing protein 0.0123 0.0906 0.1034
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0034 0.0077 0.0065
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0213 0.1733 0.1962
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0042 0.0151 0.0171
Loa Loa (eye worm) hypothetical protein 0.0034 0.0077 0.0079
Schistosoma mansoni protein kinase 0.0213 0.1733 0.1944
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0034 0.0077 0.0088
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0529 0.466 0.5276
Brugia malayi Cytochrome P450 family protein 0.0101 0.0703 0.0803
Loa Loa (eye worm) TK/EPH protein kinase 0.0213 0.1733 0.1972
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0034 0.0077 0.0088
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0075 0.0461 0.0933
Schistosoma mansoni loxhd1 0.0036 0.0102 0.0094
Echinococcus granulosus protein tyrosine kinase 0.0213 0.1733 0.1962
Trypanosoma cruzi hypothetical protein, conserved 0.0058 0.0302 0.031
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0213 0.1733 0.1944
Entamoeba histolytica tyrosin kinase, putative 0.0213 0.1733 0.3186
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0053 0.0258 0.0228
Brugia malayi Protein kinase domain containing protein 0.0213 0.1733 0.1979
Schistosoma mansoni hypothetical protein 0.0981 0.8833 1
Schistosoma mansoni aldehyde dehydrogenase 0.0142 0.108 0.1203
Entamoeba histolytica protein kinase, putative 0.0213 0.1733 0.3186
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0075 0.0461 0.1069
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0529 0.466 0.5276
Trichomonas vaginalis TKL family protein kinase 0.0213 0.1733 0.1554
Schistosoma mansoni tyrosine kinase 0.0213 0.1733 0.1944
Mycobacterium tuberculosis Probable oxidoreductase 0.0101 0.07 0.185
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0213 0.1733 0.3186
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0113 0.0811 0.0926
Schistosoma mansoni hypothetical protein 0.0218 0.1782 0.1999
Loa Loa (eye worm) TK/FER protein kinase 0.0529 0.466 0.5317
Loa Loa (eye worm) TK/FER protein kinase 0.0529 0.466 0.5317
Schistosoma mansoni cytochrome P450 0.0075 0.0461 0.0501
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0075 0.0461 0.0933
Brugia malayi exodeoxyribonuclease III family protein 0.0106 0.0749 0.0855
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0213 0.1733 0.1962
Trichomonas vaginalis conserved hypothetical protein 0.0213 0.1733 0.1554
Echinococcus multilocularis protein dispatched 1 0.0055 0.0275 0.0311
Schistosoma mansoni lipoxygenase 0.0152 0.1172 0.1307
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0034 0.0077 0.0079
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0205 0.1663 0.1883
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0213 0.1733 0.1962
Echinococcus granulosus Protein patched homolog 1 0.0048 0.0212 0.024
Trichomonas vaginalis TKL family protein kinase 0.0213 0.1733 0.1554
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0213 0.1733 0.1962
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0213 0.1733 0.1972
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0213 0.1733 0.3186
Echinococcus granulosus glucose 6 phosphate 1 dehydrogenase 0.056 0.4941 0.5594
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0205 0.1663 0.1883
Mycobacterium ulcerans aldehyde dehydrogenase 0.0142 0.108 0.2187
Schistosoma mansoni thyroid hormone receptor 0.0034 0.0077 0.0065
Echinococcus multilocularis 0.0317 0.2693 0.3049
Plasmodium falciparum protein kinase, putative 0.0213 0.1733 0.337
Loa Loa (eye worm) hypothetical protein 0.0027 0.002 0.0013
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0317 0.2693 0.3049
Onchocerca volvulus 0.0213 0.1733 0.1733
Brugia malayi Tyrosine-protein kinase PR2 0.0213 0.1733 0.1979
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0464 0.4056 0.725
Mycobacterium ulcerans glucose-6-phosphate 1-dehydrogenase 0.056 0.4941 1
Schistosoma mansoni tar DNA-binding protein 0.0123 0.0906 0.1005
Entamoeba histolytica hypothetical protein 0.0213 0.1733 0.3186
Echinococcus granulosus raf serine:threonine protein kinase 0.0213 0.1733 0.1962
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0142 0.108 0.3095
Echinococcus multilocularis NCK adaptor protein 0.0317 0.2693 0.3049
Echinococcus granulosus tar DNA binding protein 0.0123 0.0906 0.1025
Trichomonas vaginalis TKL family protein kinase 0.0213 0.1733 0.1554
Trichomonas vaginalis conserved hypothetical protein 0.0213 0.1733 0.1554
Onchocerca volvulus 0.0529 0.466 0.466
Schistosoma mansoni protein kinase 0.0213 0.1733 0.1944
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0034 0.0077 0.0065
Schistosoma mansoni ephrin receptor 0.0213 0.1733 0.1944
Schistosoma mansoni hypothetical protein 0.0244 0.2022 0.2272
Loa Loa (eye worm) SH2 domain-containing protein 0.0317 0.2693 0.3069
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0075 0.0461 0.1069
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0218 0.1782 0.2034
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0034 0.0077 0.0088
Schistosoma mansoni tyrosine-protein kinase zap-70 0.0317 0.2693 0.3033
Echinococcus multilocularis tyrosine protein kinase 0.0213 0.1733 0.1962
Trypanosoma brucei carbonic anhydrase-like protein 0.0464 0.4056 0.725
Trichomonas vaginalis D-aminoacylase, putative 0.0058 0.0302 0.0093
Loa Loa (eye worm) hypothetical protein 0.0058 0.0302 0.0336
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0357 0.3067 0.3502
Echinococcus granulosus fibroblast growth factor receptor 4 0.0213 0.1733 0.1962
Brugia malayi CHE-14 protein 0.0048 0.0212 0.0242
Onchocerca volvulus 0.0529 0.466 0.466
Trypanosoma cruzi PAB1-binding protein , putative 0.0042 0.015 0.0029
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0213 0.1733 0.3186
Trichomonas vaginalis TK family protein kinase 0.0213 0.1733 0.1554
Trichomonas vaginalis TKL family protein kinase 0.0213 0.1733 0.1554
Trichomonas vaginalis TKL family protein kinase 0.0213 0.1733 0.1554
Onchocerca volvulus 0.0213 0.1733 0.1733
Leishmania major protein kinase, putative 0.0213 0.1733 0.2955
Entamoeba histolytica protein kinase, putative 0.0213 0.1733 0.3186
Echinococcus multilocularis neurogenic locus notch protein 0.0027 0.002 0.0022
Loa Loa (eye worm) TK protein kinase 0.0213 0.1733 0.1972
Echinococcus multilocularis SHC transforming protein 3 0.0317 0.2693 0.3049
Brugia malayi Protein kinase domain containing protein 0.0213 0.1733 0.1979
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0106 0.0749 0.2011
Onchocerca volvulus 0.014 0.1056 0.1056
Loa Loa (eye worm) hypothetical protein 0.0034 0.0077 0.0079
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0213 0.1733 0.1979
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0113 0.0811 0.0918
Loa Loa (eye worm) glutathione reductase 0.004 0.0135 0.0145
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0075 0.0461 0.0933
Toxoplasma gondii ABC1 family protein 0.0058 0.0302 0.0349
Echinococcus granulosus SH2 domain containing protein 7 0.0317 0.2693 0.3049
Entamoeba histolytica tyrosine kinase, putative 0.0213 0.1733 0.3186
Entamoeba histolytica SH2 domain containing protein 0.0317 0.2693 0.5421
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0075 0.0461 0.0933
Schistosoma mansoni hypothetical protein 0.0213 0.1733 0.1944
Trypanosoma cruzi protein kinase, putative 0.0213 0.1733 0.2955
Toxoplasma gondii exonuclease III APE 0.0106 0.0749 0.1279
Onchocerca volvulus 0.0213 0.1733 0.1733
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0317 0.2693 0.3049
Schistosoma mansoni rab6-interacting 0.0036 0.0102 0.0094
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0075 0.0461 0.0933
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0213 0.1733 0.1944
Entamoeba histolytica hypothetical protein 0.0213 0.1733 0.3186
Trichomonas vaginalis TKL family protein kinase 0.0213 0.1733 0.1554
Leishmania major hypothetical protein, conserved 0.0117 0.0845 0.1314
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0091 0.0606 0.1544
Echinococcus granulosus Niemann Pick C1 protein 0.0112 0.0804 0.0911
Schistosoma mansoni thyroid hormone receptor 0.0034 0.0077 0.0065
Echinococcus granulosus tyrosine protein kinase Src42A 0.0529 0.466 0.5276
Echinococcus multilocularis ecdysone induced protein 78C 0.0034 0.0077 0.0088
Loa Loa (eye worm) hypothetical protein 0.0317 0.2693 0.3069
Loa Loa (eye worm) hypothetical protein 0.0058 0.0302 0.0336
Echinococcus multilocularis expressed conserved protein 0.007 0.0413 0.0468
Brugia malayi Cytochrome P450 family protein 0.0075 0.0461 0.0527
Toxoplasma gondii isocitrate dehydrogenase 0.0042 0.0151 0.0034
Entamoeba histolytica serine/threonine kinase, putative 0.0213 0.1733 0.3186
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0053 0.0258 0.0228
Echinococcus multilocularis tyrosine protein kinase Blk 0.0529 0.466 0.5276
Trypanosoma cruzi major cysteine proteinase, putative 0.0042 0.0153 0.0034
Loa Loa (eye worm) hypothetical protein 0.0357 0.3067 0.3496
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0075 0.0461 0.0933
Leishmania major cathepsin L-like protease 0.0053 0.0258 0.0228
Trypanosoma brucei cytochrome P450, putative 0.0101 0.0703 0.1051
Loa Loa (eye worm) cytochrome P450 family protein 0.0101 0.0703 0.0794
Echinococcus granulosus tyrosine protein kinase HCK 0.0213 0.1733 0.1962
Mycobacterium ulcerans beta-lactamase 0.0058 0.0302 0.0612
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0075 0.0461 0.1069
Brugia malayi Protein kinase domain containing protein 0.0213 0.1733 0.1979
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0213 0.1733 0.3186
Brugia malayi Variant SH3 domain containing protein 0.0317 0.2693 0.3075
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0034 0.0077 0.0088
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0213 0.1733 0.1972
Entamoeba histolytica protein kinase domain containing protein 0.0213 0.1733 0.3186
Trypanosoma brucei C-8 sterol isomerase, putative 0.0625 0.5544 1
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0075 0.0461 0.1069
Brugia malayi Protein kinase domain containing protein 0.0213 0.1733 0.1979
Echinococcus granulosus SH2 motif 0.0317 0.2693 0.3049
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0042 0.0151 0.0101
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0213 0.1733 0.1962
Loa Loa (eye worm) hypothetical protein 0.0034 0.0077 0.0079
Brugia malayi Cytochrome P450 family protein 0.0101 0.0703 0.0803
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0091 0.0606 0.7643
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0117 0.0845 0.1314
Brugia malayi SH2 domain containing protein 0.0529 0.466 0.5321
Loa Loa (eye worm) SH2 domain-containing protein 0.0317 0.2693 0.3069
Loa Loa (eye worm) TK protein kinase 0.0529 0.466 0.5317
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0058 0.0302 0.0336
Brugia malayi Niemann-Pick C1 protein precursor 0.0112 0.0804 0.0918
Brugia malayi Protein kinase domain containing protein 0.0529 0.466 0.5321
Schistosoma mansoni carbonic anhydrase-related 0.0218 0.1782 0.1999
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0106 0.0749 0.1136
Loa Loa (eye worm) beta-lactamase 0.0058 0.0302 0.0336
Mycobacterium tuberculosis Probable lipase LipD 0.0058 0.0302 0.0549
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0218 0.1777 0.2012
Trichomonas vaginalis TKL family protein kinase 0.0213 0.1733 0.1554
Entamoeba histolytica protein kinase domain containing protein 0.0213 0.1733 0.3186
Loa Loa (eye worm) hypothetical protein 0.0213 0.1733 0.1972
Trichomonas vaginalis TKL family protein kinase 0.0213 0.1733 0.1554
Trichomonas vaginalis TKL family protein kinase 0.0213 0.1733 0.1554
Echinococcus granulosus tyrosine protein kinase Fyn 0.0529 0.466 0.5276
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0034 0.0077 0.0088
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0213 0.1733 0.1944
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0106 0.0749 0.1136
Schistosoma mansoni tyrosine kinase 0.0213 0.1733 0.1944
Loa Loa (eye worm) hypothetical protein 0.0317 0.2693 0.3069
Schistosoma mansoni hypothetical protein 0.0046 0.0196 0.02
Trypanosoma cruzi protein kinase, putative 0.0213 0.1733 0.2955
Entamoeba histolytica hypothetical protein 0.0213 0.1733 0.3186
Echinococcus multilocularis geminin 0.0981 0.8833 1
Brugia malayi Tyrosine-protein kinase abl-1 0.0529 0.466 0.5321
Trichomonas vaginalis TKL family protein kinase 0.0213 0.1733 0.1554
Plasmodium falciparum glutathione reductase 0.004 0.0135 0.0066
Loa Loa (eye worm) cytochrome P450 family protein 0.0127 0.0936 0.1061
Trichomonas vaginalis TKL family protein kinase 0.0213 0.1733 0.1554
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0213 0.1733 0.3186
Echinococcus multilocularis heat shock protein 70 0.0213 0.1733 0.1962
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0218 0.1782 0.2034
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0053 0.0258 0.0228
Brugia malayi laminin alpha chain 0.0027 0.002 0.0023
Brugia malayi Protein kinase domain containing protein 0.0213 0.1733 0.1979
Trypanosoma cruzi Emopamil binding protein, putative 0.0117 0.0845 0.1314
Plasmodium vivax SET domain protein, putative 0.014 0.1056 0.1971
Brugia malayi hypothetical protein 0.0115 0.0826 0.0943
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0213 0.1733 0.3326
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0213 0.1733 0.3186
Giardia lamblia Glucose-6-phosphate 1-dehydrogenase 0.056 0.4941 1
Echinococcus granulosus NCK adaptor protein 0.0317 0.2693 0.3049
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0213 0.1733 0.1962
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0106 0.0749 0.0848
Entamoeba histolytica protein kinase, putative 0.0213 0.1733 0.3186
Loa Loa (eye worm) SH2 domain-containing protein 0.0317 0.2693 0.3069
Mycobacterium tuberculosis Probable dehydrogenase 0.0091 0.0606 0.1544
Loa Loa (eye worm) TK/ALK protein kinase 0.0213 0.1733 0.1972
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0034 0.0077 0.0088
Loa Loa (eye worm) hypothetical protein 0.0213 0.1733 0.1972
Brugia malayi SH2 domain containing protein 0.0317 0.2693 0.3075
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0213 0.1733 0.1962
Onchocerca volvulus Bile acid receptor homolog 0.0034 0.0077 0.0077
Trichomonas vaginalis TKL family protein kinase 0.0213 0.1733 0.1554
Echinococcus multilocularis suppressor of cytokine signaling 6 0.0317 0.2693 0.3049
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0142 0.108 0.1748
Echinococcus multilocularis Niemann Pick C1 protein 0.016 0.125 0.1415
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0317 0.2693 0.3049
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0213 0.1733 0.1962
Schistosoma mansoni patched 1 0.0048 0.0212 0.0218
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0218 0.1782 0.2034
Brugia malayi beta-lactamase family protein 0.0058 0.0302 0.0345
Echinococcus granulosus thioredoxin glutathione reductase 0.004 0.0135 0.0152
Loa Loa (eye worm) hypothetical protein 0.0112 0.0804 0.091
Mycobacterium ulcerans aldehyde dehydrogenase 0.0142 0.108 0.2187
Trichomonas vaginalis TKL family protein kinase 0.0213 0.1733 0.1554
Schistosoma mansoni hypothetical protein 0.0075 0.0461 0.0501
Mycobacterium ulcerans hypothetical protein 0.0058 0.0302 0.0612
Brugia malayi ecdysteroid receptor 0.0034 0.0077 0.0088
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0053 0.0258 0.0228
Toxoplasma gondii glucose-6-phosphate 1-dehydrogenase 0.0366 0.3146 0.6265
Echinococcus granulosus epidermal growth factor receptor 0.0213 0.1733 0.1962
Plasmodium falciparum tyrosine kinase-like protein 0.0213 0.1733 0.337
Trichomonas vaginalis TKL family protein kinase 0.0213 0.1733 0.1554
Schistosoma mansoni ap endonuclease 0.0106 0.0749 0.0828
Echinococcus multilocularis SH2 domain containing adapter protein F 0.0317 0.2693 0.3049
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0106 0.0749 0.0848
Entamoeba histolytica cysteine surface protein, putative 0.0213 0.1733 0.3186
Schistosoma mansoni tyrosine kinase 0.0213 0.1733 0.1944
Echinococcus granulosus slit 2 protein 0.0027 0.002 0.0022
Loa Loa (eye worm) TK/FER protein kinase 0.0213 0.1733 0.1972
Entamoeba histolytica hypothetical protein 0.0098 0.0673 0.0718
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0075 0.0461 0.1069
Schistosoma mansoni carbonic anhydrase-related 0.0218 0.1782 0.1999
Entamoeba histolytica receptor protein kinase, putative 0.0213 0.1733 0.3186
Schistosoma mansoni tensin 0.0317 0.2693 0.3033
Brugia malayi Protein kinase domain containing protein 0.0213 0.1733 0.1979
Trichomonas vaginalis TKL family protein kinase 0.0213 0.1733 0.1554
Echinococcus multilocularis beta LACTamase domain containing family member 0.0058 0.0302 0.0342
Trypanosoma cruzi cysteine peptidase, putative 0.0053 0.0258 0.0228
Echinococcus granulosus SHC transforming protein 3 0.0317 0.2693 0.3049
Onchocerca volvulus Tyrosine kinase homolog 0.0213 0.1733 0.1733
Trichomonas vaginalis TKL family protein kinase 0.0213 0.1733 0.1554
Trypanosoma cruzi Emopamil binding protein, putative 0.0117 0.0845 0.1314
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0317 0.2693 0.3049
Schistosoma mansoni serine/threonine protein kinase 0.0213 0.1733 0.1944
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0098 0.0673 0.0762
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0034 0.0077 0.0088
Entamoeba histolytica protein kinase domain containing protein 0.0213 0.1733 0.3186
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0075 0.0461 0.1069
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0213 0.1733 0.1944
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0075 0.0461 0.0933
Brugia malayi hypothetical protein 0.0027 0.0014 0.0016
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0075 0.0461 0.1069
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0106 0.0749 0.0847
Giardia lamblia Protein 21.1 0.0213 0.1733 0.2347
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0529 0.466 0.5276
Entamoeba histolytica protein kinase domain containing protein 0.0213 0.1733 0.3186
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0075 0.0461 0.0933
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.0317 0.2693 0.2693
Brugia malayi Protein kinase domain containing protein 0.0529 0.466 0.5321
Brugia malayi SH2 domain containing protein 0.0317 0.2693 0.3075
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0034 0.0077 0.0088
Echinococcus granulosus tyrosine protein kinase csk 0.0213 0.1733 0.1962
Loa Loa (eye worm) transcription factor SMAD2 0.0107 0.0755 0.0853
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0034 0.0077 0.0088
Loa Loa (eye worm) TK/FER protein kinase 0.0213 0.1733 0.1972
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0213 0.1733 0.3186
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0213 0.1733 0.1962
Leishmania major cytochrome p450-like protein 0.0075 0.0461 0.0604
Brugia malayi PAS domain containing protein 0.0034 0.0082 0.0094
Entamoeba histolytica protein kinase domain containing protein 0.0213 0.1733 0.3186
Brugia malayi RhoGAP domain containing protein 0.0317 0.2693 0.3075
Schistosoma mansoni signal transduction protein lnk-related 0.0317 0.2693 0.3033
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0213 0.1733 0.3186
Loa Loa (eye worm) TK/Met protein kinase 0.0213 0.1733 0.1972
Loa Loa (eye worm) TK/ACK protein kinase 0.0213 0.1733 0.1972
Schistosoma mansoni tyrosine kinase 0.0213 0.1733 0.1944
Schistosoma mansoni tyrosine kinase 0.0529 0.466 0.5265
Echinococcus multilocularis insulin receptor 0.0213 0.1733 0.1962
Echinococcus multilocularis pikachurin 0.0027 0.002 0.0022
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0098 0.0673 0.0762
Entamoeba histolytica protein kinase domain containing protein 0.0213 0.1733 0.3186
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0053 0.0258 0.0228
Loa Loa (eye worm) hypothetical protein 0.0213 0.1733 0.1972
Mycobacterium tuberculosis Conserved protein 0.0058 0.0302 0.0549
Echinococcus granulosus neurogenic locus notch protein 0.0027 0.002 0.0022
Mycobacterium tuberculosis Conserved protein 0.0058 0.0302 0.0549
Onchocerca volvulus 0.0058 0.0302 0.0302
Schistosoma mansoni steroid hormone receptor ad4bp 0.0034 0.0077 0.0065
Entamoeba histolytica protein kinase domain containing protein 0.0213 0.1733 0.3186
Schistosoma mansoni tyrosine kinase 0.0213 0.1733 0.1944
Echinococcus granulosus geminin 0.0981 0.8833 1
Schistosoma mansoni hypothetical protein 0.0036 0.0102 0.0094
Echinococcus multilocularis natriuretic peptide receptor 1 0.0213 0.1733 0.1962
Schistosoma mansoni adapter molecule crk 0.0317 0.2693 0.3033
Schistosoma mansoni tensin 0.0317 0.2693 0.3033
Echinococcus granulosus SH2 motif 0.0317 0.2693 0.3049
Brugia malayi hypothetical protein 0.0042 0.015 0.0171
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0213 0.1733 0.1962
Loa Loa (eye worm) hypothetical protein 0.0036 0.0102 0.0108
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0034 0.0077 0.0088
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0075 0.0461 0.0933
Loa Loa (eye worm) TK/FER protein kinase 0.0213 0.1733 0.1972
Echinococcus granulosus expressed conserved protein 0.007 0.0413 0.0468
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0213 0.1733 0.1979
Brugia malayi Protein kinase domain containing protein 0.0213 0.1733 0.1979
Loa Loa (eye worm) TK/FER protein kinase 0.0529 0.466 0.5317
Brugia malayi Protein kinase domain containing protein 0.0529 0.466 0.5321
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0464 0.4056 0.458
Leishmania major protein kinase, putative 0.0213 0.1733 0.2955
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0048 0.0212 0.0233
Schistosoma mansoni single-minded 0.0034 0.0082 0.0071
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0042 0.0151 0.0149
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0218 0.1777 0.2012
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0205 0.1663 0.1865
Brugia malayi C-terminal src kinase protein 1 0.0213 0.1733 0.1979
Echinococcus multilocularis tyrosine protein kinase Srms 0.0529 0.466 0.5276
Onchocerca volvulus 0.0529 0.466 0.466
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0075 0.0461 0.1069
Mycobacterium tuberculosis Probable reductase 0.0091 0.0606 0.1544
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.014 0.1056 0.1176
Trypanosoma cruzi cysteine peptidase, putative 0.0053 0.0258 0.0228
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0317 0.2693 0.3075
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.056 0.4941 0.4831
Plasmodium vivax glutathione reductase, putative 0.004 0.0135 0.0066
Trichomonas vaginalis TKL family protein kinase 0.0213 0.1733 0.1554
Leishmania major cytochrome p450-like protein 0.0075 0.0461 0.0604
Echinococcus multilocularis SH2 motif 0.0317 0.2693 0.3049
Onchocerca volvulus 0.0117 0.0845 0.0845
Brugia malayi Variant SH3 domain containing protein 0.0317 0.2693 0.3075
Echinococcus multilocularis expressed conserved protein 0.0105 0.0741 0.0839
Brugia malayi steroid hormone receptor 0.0034 0.0077 0.0088
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0213 0.1733 0.1979
Echinococcus multilocularis GPCR, family 2 0.0113 0.0811 0.0918
Mycobacterium tuberculosis Possible penicillin-binding protein 0.037 0.3191 1
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0034 0.0077 0.0088
Entamoeba histolytica protein kinase domain containing protein 0.0213 0.1733 0.3186
Onchocerca volvulus 0.0529 0.466 0.466
Trichomonas vaginalis AGC family protein kinase 0.0213 0.1733 0.1554
Brugia malayi beta-lactamase family protein 0.0058 0.0302 0.0345
Loa Loa (eye worm) TK/ROR protein kinase 0.0213 0.1733 0.1972
Schistosoma mansoni tyrosine kinase 0.0213 0.1733 0.1944
Onchocerca volvulus 0.0317 0.2693 0.2693
Trichomonas vaginalis TKL family protein kinase 0.0213 0.1733 0.1554
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0205 0.1663 0.1892
Echinococcus granulosus growth factor receptor bound protein 2 0.0317 0.2693 0.3049
Trichomonas vaginalis protein tyrosine kinase, putative 0.0213 0.1733 0.1554
Entamoeba histolytica tyrosine kinase, putative 0.0213 0.1733 0.3186
Echinococcus granulosus tyrosine kinase 0.0213 0.1733 0.1962
Schistosoma mansoni protein kinase 0.0213 0.1733 0.1944
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0042 0.0151 0.0171
Entamoeba histolytica protein kinase domain containing protein 0.0213 0.1733 0.3186
Onchocerca volvulus 0.0058 0.0302 0.0302
Entamoeba histolytica tyrosin kinase, putative 0.0213 0.1733 0.3186
Trypanosoma brucei PAB1-binding protein , putative 0.0042 0.015 0.0029
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0213 0.1733 0.1962
Loa Loa (eye worm) hypothetical protein 0.0317 0.2693 0.3069
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0101 0.0703 0.1423
Schistosoma mansoni hypothetical protein 0.0317 0.2693 0.3033
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0213 0.1733 0.1962
Echinococcus granulosus histone lysine methyltransferase setb 0.014 0.1056 0.1196
Brugia malayi Thioredoxin reductase 0.004 0.0135 0.0154
Echinococcus granulosus lipoxygenase domain containing protein 0.0036 0.0102 0.0116
Onchocerca volvulus 0.0317 0.2693 0.2693
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0066 0.0374 0.0418
Plasmodium vivax hypothetical protein, conserved 0.0058 0.0302 0.0413
Onchocerca volvulus 0.0213 0.1733 0.1733
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0213 0.1733 0.1972
Trypanosoma brucei Flagellum attachment zone protein 20 0.0213 0.1733 0.2955
Entamoeba histolytica protein kinase domain containing protein 0.0213 0.1733 0.3186
Entamoeba histolytica protein kinase domain containing protein 0.0213 0.1733 0.3186
Loa Loa (eye worm) hypothetical protein 0.0034 0.0077 0.0079
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0058 0.0302 0.0612
Echinococcus granulosus suppressor of cytokine signaling 7 0.0317 0.2693 0.3049
Mycobacterium ulcerans esterase/lipase LipP 0.0058 0.0302 0.0612
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0205 0.1663 0.1883

Activities

Activity type Activity value Assay description Source Reference
pA2 (functional) = 6 Antinociceptive activity against PGE-2 in guinea pig ileum at 3 microM ChEMBL. 7901416

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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