Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks9 | 0.0115 | 0.3243 | 0.3042 |
Schistosoma mansoni | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0296 | 0.8942 | 0.8942 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0296 | 0.8942 | 0.8942 |
Echinococcus granulosus | g protein coupled receptor | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0296 | 0.8942 | 0.8942 |
Echinococcus granulosus | g-protein coupled receptor | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Brugia malayi | G-protein coupled receptor | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0296 | 0.8942 | 0.8942 |
Brugia malayi | Dopamine receptor protein 2 | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0296 | 0.8942 | 0.8942 |
Brugia malayi | G protein-coupled receptor | 0.0296 | 0.8942 | 0.8942 |
Echinococcus granulosus | neuropeptide s receptor | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | neuropeptide receptor | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | opsin-like receptor | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0054 | 0.1317 | 0.1317 |
Brugia malayi | neuropeptide F receptor | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0071 | 0.1871 | 0.1871 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0296 | 0.8942 | 0.8942 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0296 | 0.8942 | 0.8942 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0115 | 0.3243 | 0.1689 |
Mycobacterium ulcerans | 3-oxoacyl-(acyl carrier protein) synthase II | 0.0329 | 1 | 1 |
Loa Loa (eye worm) | TYRA-2 protein | 0.0296 | 0.8942 | 0.8942 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0054 | 0.1317 | 0.1317 |
Echinococcus multilocularis | g protein coupled receptor | 0.0296 | 0.8942 | 0.8942 |
Mycobacterium tuberculosis | 3-oxoacyl-[acyl-carrier protein] synthase 2 KasB (beta-ketoacyl-ACP synthase) (KAS I) | 0.0215 | 0.6383 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsA | 0.0115 | 0.3243 | 0.3042 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0296 | 0.8942 | 0.8942 |
Mycobacterium leprae | 3-oxoacyl-[acyl-carrier-protein] synthase 2 KasB (BETA-KETOACYL-ACP SYNTHASE) (KAS I) | 0.0215 | 0.6383 | 1 |
Wolbachia endosymbiont of Brugia malayi | 3-oxoacyl-ACP synthase | 0.0329 | 1 | 0.5 |
Mycobacterium ulcerans | polyketide synthase | 0.0115 | 0.3243 | 0.1689 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0054 | 0.1317 | 0.1317 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsA | 0.0115 | 0.3243 | 0.1689 |
Echinococcus granulosus | neuropeptide receptor | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0296 | 0.8942 | 0.8942 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0296 | 0.8942 | 0.8942 |
Brugia malayi | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0296 | 0.8942 | 0.8942 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | neuropeptide receptor | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | amine GPCR | 0.0296 | 0.8942 | 0.8942 |
Chlamydia trachomatis | 3-oxoacyl-ACP synthase | 0.0329 | 1 | 0.5 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0296 | 0.8942 | 0.8942 |
Trypanosoma cruzi | beta-ketoacyl synthase family protein, putative | 0.0329 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0115 | 0.3243 | 0.1689 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0296 | 0.8942 | 0.8942 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0296 | 0.8942 | 0.8942 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks7 | 0.0115 | 0.3243 | 0.3042 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0296 | 0.8942 | 0.8942 |
Brugia malayi | larval opioid receptor | 0.0296 | 0.8942 | 0.8942 |
Toxoplasma gondii | AMP-binding enzyme domain-containing protein | 0.0115 | 0.3243 | 0.1689 |
Echinococcus multilocularis | g protein coupled receptor | 0.0296 | 0.8942 | 0.8942 |
Onchocerca volvulus | 0.0296 | 0.8942 | 1 | |
Schistosoma mansoni | 3-oxoacyl-[ACP] synthase | 0.0329 | 1 | 1 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Onchocerca volvulus | 0.0296 | 0.8942 | 1 | |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0296 | 0.8942 | 0.8942 |
Onchocerca volvulus | 0.0296 | 0.8942 | 1 | |
Schistosoma mansoni | adenoreceptor | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | biogenic amine receptor | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | amine GPCR | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | biogenic amine receptor | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | neuropeptide receptor | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0296 | 0.8942 | 0.8942 |
Echinococcus granulosus | orexin receptor type 2 | 0.0296 | 0.8942 | 0.8942 |
Brugia malayi | Serotonin receptor | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | neuropeptide receptor | 0.0296 | 0.8942 | 0.8942 |
Onchocerca volvulus | 0.0296 | 0.8942 | 1 | |
Brugia malayi | Dopamine receptor protein 1 | 0.0296 | 0.8942 | 0.8942 |
Leishmania major | beta-ketoacyl synthase family protein, putative,3-oxoacyl-acyl carrier protein synthase ii, putative | 0.0329 | 1 | 1 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0054 | 0.1317 | 0.1317 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.0296 | 0.8942 | 0.8942 |
Mycobacterium ulcerans | multifunctional mycocerosic acid synthase membrane-associated Mas | 0.0115 | 0.3243 | 0.1689 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Echinococcus granulosus | neuropeptide receptor | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | opsin-like receptor | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | sex peptide receptor | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | g-protein coupled receptor | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | myosin xvIII | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks15 | 0.0115 | 0.3243 | 0.3042 |
Brugia malayi | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | serotonin receptor | 0.0296 | 0.8942 | 0.8942 |
Brugia malayi | follicle stimulating hormone receptor | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | serotonin receptor | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Brugia malayi | Serotonin receptor | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0115 | 0.3243 | 0.3243 |
Echinococcus granulosus | somatostatin receptor | 0.0296 | 0.8942 | 0.8942 |
Onchocerca volvulus | 0.0296 | 0.8942 | 1 | |
Onchocerca volvulus | 0.0115 | 0.3243 | 0.3627 | |
Brugia malayi | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0115 | 0.3243 | 0.3243 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Mycobacterium ulcerans | polyketide synthase Pks9 | 0.0115 | 0.3243 | 0.1689 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0296 | 0.8942 | 0.8942 |
Trypanosoma cruzi | beta-ketoacyl synthase family protein, putative | 0.0329 | 1 | 0.5 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0296 | 0.8942 | 0.8942 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0296 | 0.8942 | 0.8942 |
Trypanosoma brucei | beta-ketoacyl-ACP synthase | 0.0329 | 1 | 0.5 |
Brugia malayi | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.0296 | 0.8942 | 0.8942 |
Brugia malayi | Dopamine receptor | 0.0296 | 0.8942 | 0.8942 |
Echinococcus granulosus | serotonin receptor | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0296 | 0.8942 | 0.8942 |
Mycobacterium tuberculosis | Polyketide synthetase MbtC (polyketide synthase) | 0.0115 | 0.3243 | 0.3042 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsE | 0.0115 | 0.3243 | 0.1689 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.0296 | 0.8942 | 0.8942 |
Echinococcus granulosus | 3 oxoacyl acyl carrier protein synthase | 0.0329 | 1 | 1 |
Schistosoma mansoni | amine GPCR | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | opsin-like receptor | 0.0296 | 0.8942 | 0.8942 |
Toxoplasma gondii | 3-oxoacyl-acyl-carrier protein synthase I/II, putative | 0.0329 | 1 | 1 |
Mycobacterium ulcerans | polyketide synthase | 0.0115 | 0.3243 | 0.1689 |
Toxoplasma gondii | beta-ketoacyl synthase, N-terminal domain-containing protein | 0.0115 | 0.3243 | 0.1689 |
Echinococcus granulosus | g protein coupled receptor | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0296 | 0.8942 | 0.8942 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.0296 | 0.8942 | 0.8942 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0054 | 0.1317 | 0.1317 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0296 | 0.8942 | 0.8942 |
Onchocerca volvulus | 0.0296 | 0.8942 | 1 | |
Mycobacterium ulcerans | fatty acid synthase Fas | 0.0115 | 0.3243 | 0.1689 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsC | 0.0115 | 0.3243 | 0.1689 |
Mycobacterium tuberculosis | Polyketide synthase Pks13 | 0.0115 | 0.3243 | 0.3042 |
Brugia malayi | GnHR receptor homolog | 0.0296 | 0.8942 | 0.8942 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks8 | 0.0115 | 0.3243 | 0.3042 |
Onchocerca volvulus | 0.0296 | 0.8942 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | allatostatin A receptor | 0.0296 | 0.8942 | 0.8942 |
Brugia malayi | G-protein coupled receptor | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | fmrfamide receptor | 0.0296 | 0.8942 | 0.8942 |
Echinococcus granulosus | allatostatin A receptor | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsD | 0.0115 | 0.3243 | 0.3042 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Echinococcus granulosus | sex peptide receptor | 0.0296 | 0.8942 | 0.8942 |
Brugia malayi | ORL1-like opioid receptor | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0296 | 0.8942 | 0.8942 |
Onchocerca volvulus | Fatty acid synthase homolog | 0.0115 | 0.3243 | 0.3627 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0296 | 0.8942 | 0.8942 |
Brugia malayi | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0296 | 0.8942 | 0.8942 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0071 | 0.1871 | 0.1871 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0296 | 0.8942 | 0.8942 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0115 | 0.3243 | 0.1689 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0296 | 0.8942 | 0.8942 |
Brugia malayi | RE15519p | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | g protein coupled receptor | 0.0296 | 0.8942 | 0.8942 |
Mycobacterium tuberculosis | Probable membrane bound polyketide synthase Pks6 | 0.0115 | 0.3243 | 0.3042 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0296 | 0.8942 | 0.8942 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | amine GPCR | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0296 | 0.8942 | 0.8942 |
Mycobacterium ulcerans | polyketide synthase MbtC | 0.0115 | 0.3243 | 0.1689 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0296 | 0.8942 | 0.8942 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0296 | 0.8942 | 0.8942 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsD | 0.0115 | 0.3243 | 0.1689 |
Mycobacterium leprae | 3-oxoacyl-[acyl-carrier-protein] synthase 1 KasA (BETA-KETOACYL-ACP SYNTHASE) (KAS I) | 0.0215 | 0.6383 | 1 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.0296 | 0.8942 | 0.8942 |
Onchocerca volvulus | 0.0296 | 0.8942 | 1 | |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Brugia malayi | Melatonin receptor type 1A | 0.0296 | 0.8942 | 0.8942 |
Brugia malayi | oxidoreductase, zinc-binding dehydrogenase family protein | 0.0115 | 0.3243 | 0.3243 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0054 | 0.1317 | 0.1317 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsB | 0.0115 | 0.3243 | 0.1689 |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.0296 | 0.8942 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Onchocerca volvulus | 0.0296 | 0.8942 | 1 | |
Brugia malayi | AKH receptor | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | neuropeptide receptor | 0.0296 | 0.8942 | 0.8942 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0296 | 0.8942 | 0.8942 |
Mycobacterium tuberculosis | Probable fatty acid synthase Fas (fatty acid synthetase) | 0.0115 | 0.3243 | 0.3042 |
Echinococcus granulosus | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Brugia malayi | sulfakinin receptor protein | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Brugia malayi | putative neuropeptide receptor | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0296 | 0.8942 | 0.8942 |
Onchocerca volvulus | 0.0296 | 0.8942 | 1 | |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0054 | 0.1317 | 0.1317 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0296 | 0.8942 | 0.8942 |
Toxoplasma gondii | type I fatty acid synthase, putative | 0.0115 | 0.3243 | 0.1689 |
Brugia malayi | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0296 | 0.8942 | 0.8942 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0296 | 0.8942 | 0.8942 |
Onchocerca volvulus | 0.0296 | 0.8942 | 1 | |
Echinococcus multilocularis | fmrfamide receptor | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0296 | 0.8942 | 0.8942 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | somatostatin receptor | 0.0296 | 0.8942 | 0.8942 |
Onchocerca volvulus | 0.0296 | 0.8942 | 1 | |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | biogenic amine receptor | 0.0296 | 0.8942 | 0.8942 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsC | 0.0115 | 0.3243 | 0.3042 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Plasmodium vivax | 3-oxoacyl-[acyl-carrier-protein] synthase i/ii, putative | 0.0329 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0296 | 0.8942 | 0.8942 |
Mycobacterium tuberculosis | 3-oxoacyl-[acyl-carrier protein] synthase 1 KasA (beta-ketoacyl-ACP synthase) (KAS I) | 0.0215 | 0.6383 | 1 |
Echinococcus granulosus | fmrfamide receptor | 0.0296 | 0.8942 | 0.8942 |
Onchocerca volvulus | 0.0296 | 0.8942 | 1 | |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0296 | 0.8942 | 0.8942 |
Brugia malayi | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Plasmodium falciparum | 3-oxoacyl-acyl-carrier protein synthase I/II | 0.0329 | 1 | 0.5 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.0296 | 0.8942 | 0.8942 |
Mycobacterium tuberculosis | Polyketide synthase Pks2 | 0.0115 | 0.3243 | 0.3042 |
Brugia malayi | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Mycobacterium ulcerans | 3-oxoacyl-(acyl carrier protein) synthase II | 0.0329 | 1 | 1 |
Echinococcus granulosus | g protein coupled receptor | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0071 | 0.1871 | 0.1871 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0296 | 0.8942 | 0.8942 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.0296 | 0.8942 | 0.8942 |
Mycobacterium tuberculosis | Polyketide synthase Pks12 | 0.0115 | 0.3243 | 0.3042 |
Toxoplasma gondii | type I fatty acid synthase, putative | 0.0115 | 0.3243 | 0.1689 |
Echinococcus multilocularis | 3 oxoacyl (acyl carrier protein) synthase | 0.0329 | 1 | 1 |
Loa Loa (eye worm) | beta-ketoacyl synthase domain-containing protein | 0.0329 | 1 | 1 |
Brugia malayi | neuropeptide F receptor | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | amine GPCR | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0296 | 0.8942 | 0.8942 |
Mycobacterium ulcerans | polyketide synthase Pks13 | 0.0115 | 0.3243 | 0.1689 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.0296 | 0.8942 | 0.8942 |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.0296 | 0.8942 | 1 |
Onchocerca volvulus | 0.0296 | 0.8942 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | neuropeptide receptor | 0.0296 | 0.8942 | 0.8942 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks5 | 0.0115 | 0.3243 | 0.3042 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0296 | 0.8942 | 0.8942 |
Onchocerca volvulus | 0.0296 | 0.8942 | 1 | |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0054 | 0.1317 | 0.1317 |
Brugia malayi | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Brugia malayi | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | histamine h1 receptor | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Onchocerca volvulus | 0.0296 | 0.8942 | 1 | |
Echinococcus multilocularis | orexin receptor type 2 | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.0296 | 0.8942 | 0.8942 |
Onchocerca volvulus | 0.0296 | 0.8942 | 1 | |
Brugia malayi | Beta-ketoacyl synthase, N-terminal domain containing protein | 0.0115 | 0.3243 | 0.3243 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0054 | 0.1317 | 0.1317 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0071 | 0.1871 | 0.1871 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0296 | 0.8942 | 0.8942 |
Mycobacterium tuberculosis | Probable multifunctional mycocerosic acid synthase membrane-associated Mas | 0.0115 | 0.3243 | 0.3042 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
MIC (functional) | = 500 ug ml-1 | Antimicrobial activity against Escherichia coli MTCC 443 after 24 to 48 hr by broth microdilution method | ChEMBL. | No reference |
MIC (functional) | = 1000 ug ml-1 | Antimicrobial activity against Candida albicans MTCC 227 after 24 to 48 hr by broth microdilution method | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.