Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0296 | 0.8942 | 1 | |
Echinococcus granulosus | dro:myosuppressin receptor | 0.0296 | 0.8942 | 0.8942 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0296 | 0.8942 | 0.8942 |
Echinococcus granulosus | serotonin receptor | 0.0296 | 0.8942 | 0.8942 |
Plasmodium falciparum | 3-oxoacyl-acyl-carrier protein synthase I/II | 0.0329 | 1 | 0.5 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | biogenic amine receptor | 0.0296 | 0.8942 | 0.8942 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Onchocerca volvulus | 0.0296 | 0.8942 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0296 | 0.8942 | 0.8942 |
Echinococcus granulosus | sex peptide receptor | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.0296 | 0.8942 | 0.8942 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | 3-oxoacyl-[ACP] synthase | 0.0329 | 1 | 1 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0296 | 0.8942 | 0.8942 |
Trypanosoma cruzi | beta-ketoacyl synthase family protein, putative | 0.0329 | 1 | 0.5 |
Schistosoma mansoni | opsin-like receptor | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.0296 | 0.8942 | 0.8942 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0296 | 0.8942 | 0.8942 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.0296 | 0.8942 | 0.8942 |
Onchocerca volvulus | 0.0296 | 0.8942 | 1 | |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Onchocerca volvulus | 0.0296 | 0.8942 | 1 | |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0296 | 0.8942 | 0.8942 |
Onchocerca volvulus | 0.0296 | 0.8942 | 1 | |
Brugia malayi | G-protein coupled receptor | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Brugia malayi | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0296 | 0.8942 | 0.8942 |
Mycobacterium tuberculosis | Probable fatty acid synthase Fas (fatty acid synthetase) | 0.0115 | 0.3243 | 0.3042 |
Echinococcus granulosus | g protein coupled receptor | 0.0296 | 0.8942 | 0.8942 |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.0296 | 0.8942 | 1 |
Brugia malayi | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0296 | 0.8942 | 0.8942 |
Brugia malayi | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0296 | 0.8942 | 0.8942 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0296 | 0.8942 | 0.8942 |
Onchocerca volvulus | 0.0296 | 0.8942 | 1 | |
Echinococcus granulosus | g protein coupled receptor | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | myosin xvIII | 0.0296 | 0.8942 | 0.8942 |
Onchocerca volvulus | 0.0296 | 0.8942 | 1 | |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.0296 | 0.8942 | 0.8942 |
Brugia malayi | Dopamine receptor protein 1 | 0.0296 | 0.8942 | 0.8942 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0054 | 0.1317 | 0.1317 |
Brugia malayi | oxidoreductase, zinc-binding dehydrogenase family protein | 0.0115 | 0.3243 | 0.3243 |
Loa Loa (eye worm) | hypothetical protein | 0.0115 | 0.3243 | 0.3243 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Chlamydia trachomatis | 3-oxoacyl-ACP synthase | 0.0329 | 1 | 0.5 |
Brugia malayi | Serotonin receptor | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Onchocerca volvulus | Fatty acid synthase homolog | 0.0115 | 0.3243 | 0.3627 |
Brugia malayi | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Brugia malayi | follicle stimulating hormone receptor | 0.0296 | 0.8942 | 0.8942 |
Toxoplasma gondii | 3-oxoacyl-acyl-carrier protein synthase I/II, putative | 0.0329 | 1 | 1 |
Echinococcus granulosus | g protein coupled receptor | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Echinococcus granulosus | neuropeptide receptor | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsC | 0.0115 | 0.3243 | 0.3042 |
Brugia malayi | Dopamine receptor protein 2 | 0.0296 | 0.8942 | 0.8942 |
Plasmodium vivax | 3-oxoacyl-[acyl-carrier-protein] synthase i/ii, putative | 0.0329 | 1 | 0.5 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0296 | 0.8942 | 0.8942 |
Mycobacterium tuberculosis | Probable membrane bound polyketide synthase Pks6 | 0.0115 | 0.3243 | 0.3042 |
Brugia malayi | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Brugia malayi | sulfakinin receptor protein | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | amine GPCR | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0054 | 0.1317 | 0.1317 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | serotonin receptor | 0.0296 | 0.8942 | 0.8942 |
Mycobacterium tuberculosis | Polyketide synthase Pks13 | 0.0115 | 0.3243 | 0.3042 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0296 | 0.8942 | 0.8942 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0296 | 0.8942 | 0.8942 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Brugia malayi | neuropeptide F receptor | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0296 | 0.8942 | 0.8942 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks15 | 0.0115 | 0.3243 | 0.3042 |
Echinococcus granulosus | g-protein coupled receptor | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Brugia malayi | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsA | 0.0115 | 0.3243 | 0.3042 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0296 | 0.8942 | 0.8942 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0071 | 0.1871 | 0.1871 |
Brugia malayi | GnHR receptor homolog | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | fmrfamide receptor | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0054 | 0.1317 | 0.1317 |
Echinococcus granulosus | neuropeptide receptor | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0296 | 0.8942 | 0.8942 |
Mycobacterium tuberculosis | Polyketide synthase Pks2 | 0.0115 | 0.3243 | 0.3042 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0296 | 0.8942 | 0.8942 |
Onchocerca volvulus | 0.0296 | 0.8942 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Mycobacterium tuberculosis | Probable multifunctional mycocerosic acid synthase membrane-associated Mas | 0.0115 | 0.3243 | 0.3042 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Onchocerca volvulus | 0.0296 | 0.8942 | 1 | |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | opsin-like receptor | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | neuropeptide receptor | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0296 | 0.8942 | 0.8942 |
Brugia malayi | larval opioid receptor | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0296 | 0.8942 | 0.8942 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | somatostatin receptor | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.0296 | 0.8942 | 0.8942 |
Echinococcus granulosus | fmrfamide receptor | 0.0296 | 0.8942 | 0.8942 |
Echinococcus granulosus | neuropeptide s receptor | 0.0296 | 0.8942 | 0.8942 |
Brugia malayi | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | biogenic amine receptor | 0.0296 | 0.8942 | 0.8942 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0296 | 0.8942 | 0.8942 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsA | 0.0115 | 0.3243 | 0.1689 |
Echinococcus multilocularis | sex peptide receptor | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | g protein coupled receptor | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0296 | 0.8942 | 0.8942 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0296 | 0.8942 | 0.8942 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0071 | 0.1871 | 0.1871 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0071 | 0.1871 | 0.1871 |
Brugia malayi | G-protein coupled receptor | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0054 | 0.1317 | 0.1317 |
Brugia malayi | Dopamine receptor | 0.0296 | 0.8942 | 0.8942 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks5 | 0.0115 | 0.3243 | 0.3042 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0296 | 0.8942 | 0.8942 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0296 | 0.8942 | 0.8942 |
Brugia malayi | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0296 | 0.8942 | 0.8942 |
Mycobacterium ulcerans | 3-oxoacyl-(acyl carrier protein) synthase II | 0.0329 | 1 | 1 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0296 | 0.8942 | 0.8942 |
Mycobacterium ulcerans | polyketide synthase | 0.0115 | 0.3243 | 0.1689 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0296 | 0.8942 | 0.8942 |
Echinococcus granulosus | somatostatin receptor | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0296 | 0.8942 | 0.8942 |
Brugia malayi | AKH receptor | 0.0296 | 0.8942 | 0.8942 |
Brugia malayi | ORL1-like opioid receptor | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.0296 | 0.8942 | 0.8942 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | g-protein coupled receptor | 0.0296 | 0.8942 | 0.8942 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | allatostatin A receptor | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | neuropeptide receptor | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Echinococcus granulosus | allatostatin A receptor | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0296 | 0.8942 | 0.8942 |
Brugia malayi | G protein-coupled receptor | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0296 | 0.8942 | 0.8942 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0115 | 0.3243 | 0.1689 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.0296 | 0.8942 | 0.8942 |
Wolbachia endosymbiont of Brugia malayi | 3-oxoacyl-ACP synthase | 0.0329 | 1 | 0.5 |
Schistosoma mansoni | amine GPCR | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.0296 | 0.8942 | 0.8942 |
Echinococcus granulosus | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0071 | 0.1871 | 0.1871 |
Schistosoma mansoni | histamine h1 receptor | 0.0296 | 0.8942 | 0.8942 |
Mycobacterium ulcerans | polyketide synthase MbtC | 0.0115 | 0.3243 | 0.1689 |
Onchocerca volvulus | 0.0296 | 0.8942 | 1 | |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | TYRA-2 protein | 0.0296 | 0.8942 | 0.8942 |
Echinococcus granulosus | orexin receptor type 2 | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Onchocerca volvulus | 0.0115 | 0.3243 | 0.3627 | |
Mycobacterium tuberculosis | 3-oxoacyl-[acyl-carrier protein] synthase 2 KasB (beta-ketoacyl-ACP synthase) (KAS I) | 0.0215 | 0.6383 | 1 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0296 | 0.8942 | 0.8942 |
Brugia malayi | putative neuropeptide receptor | 0.0296 | 0.8942 | 0.8942 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0296 | 0.8942 | 0.8942 |
Mycobacterium ulcerans | polyketide synthase | 0.0115 | 0.3243 | 0.1689 |
Onchocerca volvulus | 0.0296 | 0.8942 | 1 | |
Mycobacterium ulcerans | 3-oxoacyl-(acyl carrier protein) synthase II | 0.0329 | 1 | 1 |
Trypanosoma cruzi | beta-ketoacyl synthase family protein, putative | 0.0329 | 1 | 0.5 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0296 | 0.8942 | 0.8942 |
Echinococcus granulosus | 3 oxoacyl acyl carrier protein synthase | 0.0329 | 1 | 1 |
Onchocerca volvulus | 0.0296 | 0.8942 | 1 | |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0296 | 0.8942 | 0.8942 |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.0296 | 0.8942 | 1 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsD | 0.0115 | 0.3243 | 0.3042 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0115 | 0.3243 | 0.3243 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | amine GPCR | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Brugia malayi | Serotonin receptor | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsC | 0.0115 | 0.3243 | 0.1689 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0296 | 0.8942 | 0.8942 |
Toxoplasma gondii | AMP-binding enzyme domain-containing protein | 0.0115 | 0.3243 | 0.1689 |
Onchocerca volvulus | 0.0296 | 0.8942 | 1 | |
Mycobacterium ulcerans | polyketide synthase Pks13 | 0.0115 | 0.3243 | 0.1689 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0296 | 0.8942 | 0.8942 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0296 | 0.8942 | 0.8942 |
Toxoplasma gondii | type I fatty acid synthase, putative | 0.0115 | 0.3243 | 0.1689 |
Schistosoma mansoni | biogenic amine receptor | 0.0296 | 0.8942 | 0.8942 |
Mycobacterium tuberculosis | 3-oxoacyl-[acyl-carrier protein] synthase 1 KasA (beta-ketoacyl-ACP synthase) (KAS I) | 0.0215 | 0.6383 | 1 |
Echinococcus multilocularis | fmrfamide receptor | 0.0296 | 0.8942 | 0.8942 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks9 | 0.0115 | 0.3243 | 0.3042 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | neuropeptide receptor | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | opsin-like receptor | 0.0296 | 0.8942 | 0.8942 |
Toxoplasma gondii | beta-ketoacyl synthase, N-terminal domain-containing protein | 0.0115 | 0.3243 | 0.1689 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks8 | 0.0115 | 0.3243 | 0.3042 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | serotonin receptor | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | g protein coupled receptor | 0.0296 | 0.8942 | 0.8942 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsB | 0.0115 | 0.3243 | 0.1689 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | orexin receptor type 2 | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0054 | 0.1317 | 0.1317 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Onchocerca volvulus | 0.0296 | 0.8942 | 1 | |
Mycobacterium ulcerans | multifunctional mycocerosic acid synthase membrane-associated Mas | 0.0115 | 0.3243 | 0.1689 |
Mycobacterium tuberculosis | Polyketide synthase Pks12 | 0.0115 | 0.3243 | 0.3042 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsD | 0.0115 | 0.3243 | 0.1689 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0296 | 0.8942 | 0.8942 |
Onchocerca volvulus | 0.0296 | 0.8942 | 1 | |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0296 | 0.8942 | 0.8942 |
Brugia malayi | RE15519p | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | adenoreceptor | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | neuropeptide receptor | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Mycobacterium leprae | 3-oxoacyl-[acyl-carrier-protein] synthase 1 KasA (BETA-KETOACYL-ACP SYNTHASE) (KAS I) | 0.0215 | 0.6383 | 1 |
Mycobacterium ulcerans | polyketide synthase Pks9 | 0.0115 | 0.3243 | 0.1689 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0054 | 0.1317 | 0.1317 |
Mycobacterium leprae | 3-oxoacyl-[acyl-carrier-protein] synthase 2 KasB (BETA-KETOACYL-ACP SYNTHASE) (KAS I) | 0.0215 | 0.6383 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0296 | 0.8942 | 0.8942 |
Onchocerca volvulus | 0.0296 | 0.8942 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0296 | 0.8942 | 0.8942 |
Trypanosoma brucei | beta-ketoacyl-ACP synthase | 0.0329 | 1 | 0.5 |
Echinococcus multilocularis | 3 oxoacyl (acyl carrier protein) synthase | 0.0329 | 1 | 1 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.0296 | 0.8942 | 0.8942 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks7 | 0.0115 | 0.3243 | 0.3042 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0115 | 0.3243 | 0.1689 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0054 | 0.1317 | 0.1317 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Brugia malayi | Beta-ketoacyl synthase, N-terminal domain containing protein | 0.0115 | 0.3243 | 0.3243 |
Toxoplasma gondii | type I fatty acid synthase, putative | 0.0115 | 0.3243 | 0.1689 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0296 | 0.8942 | 0.8942 |
Brugia malayi | Melatonin receptor type 1A | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0054 | 0.1317 | 0.1317 |
Leishmania major | beta-ketoacyl synthase family protein, putative,3-oxoacyl-acyl carrier protein synthase ii, putative | 0.0329 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0296 | 0.8942 | 0.8942 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0296 | 0.8942 | 0.8942 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsE | 0.0115 | 0.3243 | 0.1689 |
Mycobacterium ulcerans | fatty acid synthase Fas | 0.0115 | 0.3243 | 0.1689 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0296 | 0.8942 | 0.8942 |
Brugia malayi | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0054 | 0.1317 | 0.1317 |
Schistosoma mansoni | neuropeptide receptor | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0296 | 0.8942 | 0.8942 |
Mycobacterium tuberculosis | Polyketide synthetase MbtC (polyketide synthase) | 0.0115 | 0.3243 | 0.3042 |
Onchocerca volvulus | 0.0296 | 0.8942 | 1 | |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | amine GPCR | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0115 | 0.3243 | 0.1689 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0296 | 0.8942 | 0.8942 |
Schistosoma mansoni | neuropeptide receptor | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | beta-ketoacyl synthase domain-containing protein | 0.0329 | 1 | 1 |
Schistosoma mansoni | amine GPCR | 0.0296 | 0.8942 | 0.8942 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0296 | 0.8942 | 0.8942 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.8942 | 0.8942 |
Brugia malayi | neuropeptide F receptor | 0.0296 | 0.8942 | 0.8942 |
Echinococcus multilocularis | g protein coupled receptor | 0.0296 | 0.8942 | 0.8942 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
MIC (functional) | = 500 ug ml-1 | Antimicrobial activity against Escherichia coli MTCC 443 after 24 to 48 hr by broth microdilution method | ChEMBL. | No reference |
MIC (functional) | = 1000 ug ml-1 | Antimicrobial activity against Candida albicans MTCC 227 after 24 to 48 hr by broth microdilution method | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.