Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | aldo/keto reductase, putative | 0.0031 | 1 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0031 | 1 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0031 | 1 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0031 | 1 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0031 | 1 | 0.5 |
Echinococcus granulosus | hypothetical protein | 0.0031 | 1 | 1 |
Leishmania major | aldo-keto reductase-like protein | 0.0031 | 1 | 0.5 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0031 | 1 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0031 | 1 | 1 |
Leishmania major | prostaglandin f synthase, putative | 0.0031 | 1 | 0.5 |
Onchocerca volvulus | 0.0031 | 1 | 0.5 | |
Loa Loa (eye worm) | oxidoreductase | 0.0031 | 1 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0031 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0031 | 1 | 1 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0031 | 1 | 0.5 |
Onchocerca volvulus | 0.0031 | 1 | 0.5 | |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0031 | 1 | 0.5 |
Echinococcus granulosus | aldo keto reductase | 0.0031 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0031 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0031 | 1 | 0.5 |
Schistosoma mansoni | aldo-keto reductase | 0.0031 | 1 | 0.5 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0031 | 1 | 0.5 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0031 | 1 | 0.5 |
Trypanosoma brucei | aldo-keto reductase, putative | 0.0031 | 1 | 0.5 |
Trypanosoma brucei | prostaglandin f synthase | 0.0031 | 1 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0031 | 1 | 1 |
Onchocerca volvulus | 0.0031 | 1 | 0.5 | |
Schistosoma mansoni | pol-related | 0.0031 | 1 | 0.5 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0031 | 1 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0031 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0031 | 1 | 0.5 |
Echinococcus multilocularis | aldo keto reductase | 0.0031 | 1 | 1 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0031 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 1 | 0.5 |
Echinococcus granulosus | aldo keto reductase | 0.0031 | 1 | 1 |
Onchocerca volvulus | 0.0031 | 1 | 0.5 | |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0031 | 1 | 0.5 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0031 | 1 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0031 | 1 | 1 |
Leishmania major | prostaglandin f2-alpha synthase/D-arabinose dehydrogenase | 0.0031 | 1 | 0.5 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0031 | 1 | 0.5 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0031 | 1 | 0.5 |
Echinococcus multilocularis | aldo keto reductase | 0.0031 | 1 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0031 | 1 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0031 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0031 | 1 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0031 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0031 | 1 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0031 | 1 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0031 | 1 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0031 | 1 | 0.5 |
Schistosoma mansoni | aldo-keto reductase | 0.0031 | 1 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0031 | 1 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0031 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0031 | 1 | 1 |
Toxoplasma gondii | aldose reductase, putative | 0.0031 | 1 | 0.5 |
Entamoeba histolytica | aldose reductase, putative | 0.0031 | 1 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0031 | 1 | 0.5 |
Giardia lamblia | Aldose reductase | 0.0031 | 1 | 0.5 |
Onchocerca volvulus | 0.0031 | 1 | 0.5 | |
Mycobacterium leprae | PROBABLE OXIDOREDUCTASE | 0.0031 | 1 | 1 |
Giardia lamblia | Aldose reductase | 0.0031 | 1 | 0.5 |
Entamoeba histolytica | aldose reductase, putative | 0.0031 | 1 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0031 | 1 | 1 |
Mycobacterium ulcerans | oxidoreductase | 0.0031 | 1 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0031 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0031 | 1 | 1 |
Entamoeba histolytica | aldose reductase, putative | 0.0031 | 1 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0031 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0031 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0031 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0031 | 1 | 1 |
Onchocerca volvulus | 0.0031 | 1 | 0.5 | |
Leishmania major | aldehyde reductase, putative,oxidoreductase, putative | 0.0031 | 1 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0031 | 1 | 0.5 |
Trypanosoma cruzi | aldo-keto reductase | 0.0031 | 1 | 0.5 |
Echinococcus multilocularis | aldo keto reductase | 0.0031 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0031 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0031 | 1 | 0.5 |
Echinococcus granulosus | aldo keto reductase | 0.0031 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase | 0.0031 | 1 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Phytotoxicity (ADMET) | = 0 % | Pre-emergence phytotoxicity against Oryza sativa cv. Koshihikari (rice) assessed as phytotoxic crop injury visual ratings at 25 g ai/ha measured after 14 days post treatment under flooded conditions | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.