Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0196 | 0.5363 | 0.7503 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0042 | 0.0767 | 0.0902 |
Echinococcus granulosus | neurogenic locus notch protein 4 | 0.0063 | 0.1395 | 0.1395 |
Schistosoma mansoni | septate junction protein | 0.0063 | 0.1395 | 0.1951 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0037 | 0.0606 | 0.0091 |
Loa Loa (eye worm) | hypothetical protein | 0.0196 | 0.5363 | 0.7503 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0048 | 0.0935 | 0.0988 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0606 | 0.0848 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0064 | 0.1402 | 0.1008 |
Giardia lamblia | High cysteine protein | 0.0063 | 0.1395 | 0.5 |
Brugia malayi | EGF-like domain containing protein | 0.0063 | 0.1395 | 0.1951 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0064 | 0.1402 | 0.1008 |
Brugia malayi | Cadherin domain containing protein | 0.0063 | 0.1395 | 0.1951 |
Brugia malayi | EGF-like domain containing protein | 0.0063 | 0.1395 | 0.1951 |
Echinococcus granulosus | neurogenic locus notch protein | 0.0063 | 0.1395 | 0.1395 |
Loa Loa (eye worm) | hypothetical protein | 0.0196 | 0.5363 | 0.7503 |
Brugia malayi | beta-lactamase family protein | 0.0037 | 0.0606 | 0.0848 |
Brugia malayi | EGF-like domain containing protein | 0.0063 | 0.1395 | 0.1951 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0494 | 0.0691 |
Loa Loa (eye worm) | hypothetical protein | 0.0196 | 0.5363 | 0.7503 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0031 | 0.0417 | 0.0417 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.1395 | 0.1951 |
Echinococcus granulosus | peroxidasin | 0.0196 | 0.5363 | 0.5363 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0037 | 0.0606 | 0.0848 |
Brugia malayi | Blistered cuticle protein 3 | 0.0196 | 0.5363 | 0.7503 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0159 | 0.4243 | 0.6164 |
Echinococcus granulosus | fibropellin Ia | 0.0063 | 0.1395 | 0.1395 |
Mycobacterium ulcerans | beta-lactamase | 0.0037 | 0.0606 | 0.0091 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0606 | 0.0848 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0064 | 0.1402 | 0.1649 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0037 | 0.0606 | 0.0152 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.1395 | 0.1951 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0935 | 0.1309 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0301 | 0.8503 | 1 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.0063 | 0.1395 | 0.1951 |
Onchocerca volvulus | 0.0037 | 0.0606 | 0.0895 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0064 | 0.1402 | 0.1008 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0064 | 0.1402 | 0.1008 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0256 | 0.7147 | 1 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0058 | 0.1237 | 0.1455 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0048 | 0.0935 | 0.11 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0196 | 0.5363 | 0.7503 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0036 | 0.0573 | 0.0097 |
Schistosoma mansoni | peroxidasin | 0.0196 | 0.5363 | 0.7503 |
Brugia malayi | Muscle positioning protein 4 | 0.0063 | 0.1395 | 0.1951 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0048 | 0.0935 | 0.0988 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0606 | 0.0848 |
Loa Loa (eye worm) | hypothetical protein | 0.0196 | 0.5363 | 0.7503 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.1395 | 0.1951 |
Loa Loa (eye worm) | hypothetical protein | 0.0196 | 0.5363 | 0.7503 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0048 | 0.0935 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.1395 | 0.1951 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0256 | 0.7147 | 1 |
Brugia malayi | GCC2 and GCC3 family protein | 0.0063 | 0.1395 | 0.1951 |
Onchocerca volvulus | 0.0063 | 0.1395 | 0.2059 | |
Mycobacterium tuberculosis | Conserved protein | 0.0037 | 0.0606 | 0.0152 |
Schistosoma mansoni | slit | 0.0063 | 0.1395 | 0.1951 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.1395 | 0.1951 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0573 | 0.0801 |
Schistosoma mansoni | hypothetical protein | 0.0063 | 0.1395 | 0.1951 |
Brugia malayi | AMP-binding enzyme family protein | 0.0048 | 0.0935 | 0.1309 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0236 | 0.6563 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0256 | 0.7147 | 1 |
Onchocerca volvulus | Peroxidase homolog | 0.0196 | 0.5363 | 0.7918 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0036 | 0.0573 | 0.9448 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.0063 | 0.1395 | 0.1951 |
Brugia malayi | Pre-SET motif family protein | 0.0031 | 0.0417 | 0.0584 |
Loa Loa (eye worm) | hypothetical protein | 0.0196 | 0.5363 | 0.7503 |
Schistosoma mansoni | notch | 0.0063 | 0.1395 | 0.1951 |
Brugia malayi | AMP-binding enzyme family protein | 0.0048 | 0.0935 | 0.1309 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0031 | 0.0417 | 0.0584 |
Onchocerca volvulus | 0.0037 | 0.0606 | 0.0895 | |
Echinococcus multilocularis | neurogenic locus protein delta | 0.0063 | 0.1395 | 0.1395 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0031 | 0.0417 | 0.0417 |
Loa Loa (eye worm) | Notch2 | 0.0063 | 0.1395 | 0.1951 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.1395 | 0.1951 |
Onchocerca volvulus | 0.0051 | 0.1038 | 0.1532 | |
Mycobacterium tuberculosis | Conserved protein | 0.0037 | 0.0606 | 0.0152 |
Trichomonas vaginalis | set domain proteins, putative | 0.0243 | 0.6773 | 1 |
Mycobacterium tuberculosis | Conserved protein | 0.0037 | 0.0606 | 0.0152 |
Echinococcus multilocularis | tumor protein p63 | 0.0351 | 1 | 1 |
Echinococcus multilocularis | neural cadherin | 0.0063 | 0.1395 | 0.1395 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0048 | 0.0935 | 0.0988 |
Loa Loa (eye worm) | beta-lactamase | 0.0037 | 0.0606 | 0.0848 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0953 | 0.1333 |
Onchocerca volvulus | 0.0243 | 0.6773 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.1395 | 0.1951 |
Onchocerca volvulus | 0.0196 | 0.5363 | 0.7918 | |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.1395 | 0.1951 |
Onchocerca volvulus | Neurogenic locus notch homolog | 0.0063 | 0.1395 | 0.2059 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0031 | 0.0417 | 0.0584 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0037 | 0.0606 | 0.0713 |
Onchocerca volvulus | 0.0048 | 0.0935 | 0.1381 | |
Echinococcus multilocularis | neurogenic locus protein delta | 0.0063 | 0.1395 | 0.1395 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0606 | 0.0848 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.1395 | 0.1951 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0064 | 0.1402 | 0.1649 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.003 | 0.0384 | 0.0384 |
Mycobacterium ulcerans | hypothetical protein | 0.0159 | 0.4243 | 1 |
Echinococcus multilocularis | neurogenic locus notch protein | 0.0063 | 0.1395 | 0.1395 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0052 | 0.1044 | 0.1227 |
Onchocerca volvulus | Peroxidase homolog | 0.0196 | 0.5363 | 0.7918 |
Trichomonas vaginalis | esterase, putative | 0.0037 | 0.0606 | 0.0895 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.0063 | 0.1395 | 0.1951 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0042 | 0.0767 | 0.0902 |
Mycobacterium ulcerans | lipase LipD | 0.0037 | 0.0606 | 0.0091 |
Onchocerca volvulus | Peroxidasin homolog | 0.0196 | 0.5363 | 0.7918 |
Schistosoma mansoni | hypothetical protein | 0.0063 | 0.1395 | 0.1951 |
Echinococcus multilocularis | fibropellin Ia | 0.0063 | 0.1395 | 0.1395 |
Brugia malayi | Delta serrate ligand family protein | 0.0063 | 0.1395 | 0.1951 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0031 | 0.0417 | 0.0584 |
Schistosoma mansoni | hypothetical protein | 0.0063 | 0.1395 | 0.1951 |
Schistosoma mansoni | hypothetical protein | 0.0063 | 0.1395 | 0.1951 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.1038 | 0.1452 |
Echinococcus granulosus | notch | 0.0063 | 0.1395 | 0.1395 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.1395 | 0.1951 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0301 | 0.8503 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0063 | 0.1395 | 0.1951 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0142 | 0.3761 | 0.4424 |
Echinococcus granulosus | protein jagged 1 | 0.0063 | 0.1395 | 0.1395 |
Echinococcus granulosus | protein jagged 1 | 0.0063 | 0.1395 | 0.1395 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0573 | 0.0801 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0064 | 0.1402 | 0.1008 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.1395 | 0.1951 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0042 | 0.0767 | 0.0902 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0037 | 0.0606 | 0.0152 |
Brugia malayi | Peroxidasin | 0.0196 | 0.5363 | 0.7503 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.1395 | 0.1951 |
Brugia malayi | Animal haem peroxidase family protein | 0.0196 | 0.5363 | 0.7503 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.1395 | 0.1951 |
Echinococcus multilocularis | slit 2 protein | 0.0063 | 0.1395 | 0.1395 |
Onchocerca volvulus | 0.0196 | 0.5363 | 0.7918 | |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0573 | 0.0801 |
Leishmania major | cathepsin L-like protease | 0.0064 | 0.1402 | 0.1649 |
Loa Loa (eye worm) | hypothetical protein | 0.0196 | 0.5363 | 0.7503 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0064 | 0.1402 | 0.1008 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.1395 | 0.1951 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0036 | 0.0573 | 0.5 |
Plasmodium vivax | SET domain protein, putative | 0.0031 | 0.0417 | 0.6884 |
Echinococcus granulosus | protein jagged 2 | 0.0063 | 0.1395 | 0.1395 |
Echinococcus multilocularis | neurogenic locus notch protein 4 | 0.0063 | 0.1395 | 0.1395 |
Echinococcus granulosus | delta-like protein 1 | 0.0063 | 0.1395 | 0.1395 |
Schistosoma mansoni | cell polarity protein | 0.0063 | 0.1395 | 0.1951 |
Brugia malayi | EGF-like domain containing protein | 0.0063 | 0.1395 | 0.1951 |
Mycobacterium ulcerans | hypothetical protein | 0.0037 | 0.0606 | 0.0091 |
Loa Loa (eye worm) | hypothetical protein | 0.0196 | 0.5363 | 0.7503 |
Echinococcus granulosus | tar DNA binding protein | 0.0256 | 0.7147 | 0.7147 |
Brugia malayi | Transmembrane cell adhesion receptor mua-3 precursor, putative | 0.0063 | 0.1395 | 0.1951 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0064 | 0.1402 | 0.1008 |
Mycobacterium ulcerans | hypothetical protein | 0.0048 | 0.0935 | 0.0988 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0037 | 0.0606 | 0.0895 |
Schistosoma mansoni | notch | 0.0063 | 0.1395 | 0.1951 |
Brugia malayi | Pre-SET motif family protein | 0.0214 | 0.589 | 0.8241 |
Onchocerca volvulus | Peroxidasin homolog | 0.0196 | 0.5363 | 0.7918 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0048 | 0.0935 | 1 |
Echinococcus multilocularis | tar DNA binding protein | 0.0256 | 0.7147 | 0.7147 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0037 | 0.0606 | 0.0152 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0064 | 0.1402 | 0.1649 |
Echinococcus granulosus | neurogenic locus notch protein | 0.0063 | 0.1395 | 0.1395 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0049 | 0.0953 | 0.1333 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.005 | 0.0995 | 0.1171 |
Schistosoma mansoni | tar DNA-binding protein | 0.0256 | 0.7147 | 1 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0031 | 0.0417 | 0.2992 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0064 | 0.1402 | 0.1008 |
Onchocerca volvulus | Putative cubilin | 0.0063 | 0.1395 | 0.2059 |
Echinococcus multilocularis | peroxidasin | 0.0196 | 0.5363 | 0.5363 |
Brugia malayi | Cadherin domain containing protein | 0.0063 | 0.1395 | 0.1951 |
Loa Loa (eye worm) | blistered cuticle protein 3 | 0.0196 | 0.5363 | 0.7503 |
Onchocerca volvulus | Slit protein homolog | 0.0063 | 0.1395 | 0.2059 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0048 | 0.0935 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.1395 | 0.1951 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0048 | 0.0935 | 0.0696 |
Onchocerca volvulus | 0.0063 | 0.1395 | 0.2059 | |
Echinococcus multilocularis | protein jagged 1 | 0.0063 | 0.1395 | 0.1395 |
Onchocerca volvulus | 0.0063 | 0.1395 | 0.2059 | |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0033 | 0.0494 | 0.0691 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0606 | 0.0848 |
Echinococcus multilocularis | fat cadherin tumor suppressor | 0.0063 | 0.1395 | 0.1395 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0048 | 0.0935 | 0.0988 |
Schistosoma mansoni | notch | 0.0063 | 0.1395 | 0.1951 |
Schistosoma mansoni | hypothetical protein | 0.0063 | 0.1395 | 0.1951 |
Echinococcus granulosus | neurogenic locus protein delta | 0.0063 | 0.1395 | 0.1395 |
Schistosoma mansoni | tar DNA-binding protein | 0.0256 | 0.7147 | 1 |
Brugia malayi | EGF-like domain containing protein | 0.0063 | 0.1395 | 0.1951 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0031 | 0.0417 | 0.0584 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0049 | 0.0953 | 0.1333 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0031 | 0.0417 | 0.0417 |
Brugia malayi | EGF-like domain containing protein | 0.0063 | 0.1395 | 0.1951 |
Onchocerca volvulus | 0.0037 | 0.0606 | 0.0895 | |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0037 | 0.0606 | 0.0713 |
Brugia malayi | beta-lactamase family protein | 0.0037 | 0.0606 | 0.0848 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.0142 | 0.3761 | 0.3995 |
Loa Loa (eye worm) | hypothetical protein | 0.0196 | 0.5363 | 0.7503 |
Echinococcus granulosus | neural cadherin | 0.0063 | 0.1395 | 0.1395 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0064 | 0.1402 | 0.1008 |
Schistosoma mansoni | tar DNA-binding protein | 0.0256 | 0.7147 | 1 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0196 | 0.5363 | 0.7503 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0573 | 0.0801 |
Plasmodium vivax | hypothetical protein, conserved | 0.0037 | 0.0606 | 1 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0048 | 0.0935 | 1 |
Brugia malayi | RNA binding protein | 0.0256 | 0.7147 | 1 |
Loa Loa (eye worm) | notch protein | 0.0063 | 0.1395 | 0.1951 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.1395 | 0.1951 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0214 | 0.589 | 0.8241 |
Echinococcus multilocularis | notch | 0.0063 | 0.1395 | 0.1395 |
Onchocerca volvulus | 0.0031 | 0.0417 | 0.0616 | |
Leishmania major | cathepsin L-like protease | 0.0064 | 0.1402 | 0.1649 |
Brugia malayi | Animal haem peroxidase family protein | 0.0196 | 0.5363 | 0.7503 |
Loa Loa (eye worm) | hypothetical protein | 0.0196 | 0.5363 | 0.7503 |
Brugia malayi | beta-lactamase | 0.0037 | 0.0606 | 0.0848 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0048 | 0.0935 | 0.0696 |
Schistosoma mansoni | notch | 0.0063 | 0.1395 | 0.1951 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0037 | 0.0606 | 0.0848 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0036 | 0.0573 | 1 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0037 | 0.0606 | 0.0152 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0051 | 0.1038 | 0.1452 |
Schistosoma mansoni | laminin gamma-3 chain | 0.0063 | 0.1395 | 0.1951 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0048 | 0.0935 | 0.0988 |
Loa Loa (eye worm) | hypothetical protein | 0.0196 | 0.5363 | 0.7503 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.0142 | 0.3761 | 0.4424 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0064 | 0.1402 | 0.1649 |
Schistosoma mansoni | tar DNA-binding protein | 0.0256 | 0.7147 | 1 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0037 | 0.0606 | 0.0606 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0048 | 0.0935 | 0.0988 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.1395 | 0.1951 |
Onchocerca volvulus | 0.0196 | 0.5363 | 0.7918 | |
Leishmania major | mitochondrial DNA polymerase beta | 0.0301 | 0.8503 | 1 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.0042 | 0.0767 | 0.0203 |
Echinococcus multilocularis | neurogenic locus notch protein | 0.0063 | 0.1395 | 0.1395 |
Echinococcus multilocularis | protein jagged 1 | 0.0063 | 0.1395 | 0.1395 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0196 | 0.5363 | 0.7503 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0037 | 0.0606 | 0.0895 |
Brugia malayi | Animal haem peroxidase family protein | 0.0196 | 0.5363 | 0.7503 |
Leishmania major | hypothetical protein, conserved | 0.0037 | 0.0606 | 0.0713 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.1395 | 0.1951 |
Schistosoma mansoni | Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] | 0.0063 | 0.1395 | 0.1951 |
Brugia malayi | Animal haem peroxidase family protein | 0.0196 | 0.5363 | 0.7503 |
Brugia malayi | notch-like transmembrane receptor | 0.0063 | 0.1395 | 0.1951 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0037 | 0.0606 | 0.0895 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0037 | 0.0606 | 0.0848 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.1395 | 0.1951 |
Schistosoma mansoni | hypothetical protein | 0.0063 | 0.1395 | 0.1951 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0935 | 0.1309 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0037 | 0.0606 | 0.0895 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0196 | 0.5363 | 0.7503 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0048 | 0.0935 | 0.11 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.1395 | 0.1951 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0037 | 0.0606 | 0.0606 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.1395 | 0.1951 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0417 | 0.0584 |
Onchocerca volvulus | 0.0063 | 0.1395 | 0.2059 | |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0037 | 0.0606 | 0.0895 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0064 | 0.1402 | 0.1008 |
Onchocerca volvulus | 0.0063 | 0.1395 | 0.2059 | |
Brugia malayi | TAR-binding protein | 0.0256 | 0.7147 | 1 |
Echinococcus granulosus | slit 2 protein | 0.0063 | 0.1395 | 0.1395 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0573 | 0.0801 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0494 | 0.0691 |
Onchocerca volvulus | Chorion peroxidase homolog | 0.0196 | 0.5363 | 0.7918 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0064 | 0.1402 | 0.1008 |
Toxoplasma gondii | EGF family domain-containing protein | 0.0063 | 0.1395 | 1 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0037 | 0.0606 | 0.0152 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.1395 | 0.1951 |
Loa Loa (eye worm) | hypothetical protein | 0.0196 | 0.5363 | 0.7503 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0048 | 0.0935 | 0.11 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0048 | 0.0935 | 1 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0301 | 0.8503 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.0256 | 0.7147 | 1 |
Loa Loa (eye worm) | TAR-binding protein | 0.0256 | 0.7147 | 1 |
Brugia malayi | Animal haem peroxidase family protein | 0.0196 | 0.5363 | 0.7503 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0048 | 0.0935 | 0.0988 |
Schistosoma mansoni | notch | 0.0063 | 0.1395 | 0.1951 |
Schistosoma mansoni | notch | 0.0063 | 0.1395 | 0.1951 |
Onchocerca volvulus | Neurogenic locus notch protein homolog | 0.0063 | 0.1395 | 0.2059 |
Toxoplasma gondii | ABC1 family protein | 0.0037 | 0.0606 | 0.4347 |
Onchocerca volvulus | Dual oxidase homolog | 0.0196 | 0.5363 | 0.7918 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0037 | 0.0606 | 0.0091 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0037 | 0.0606 | 0.0152 |
Echinococcus granulosus | protein jagged 2 | 0.0063 | 0.1395 | 0.1395 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0606 | 0.0848 |
Loa Loa (eye worm) | hypothetical protein | 0.0196 | 0.5363 | 0.7503 |
Toxoplasma gondii | hypothetical protein | 0.0049 | 0.0953 | 0.6832 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0049 | 0.0953 | 0.1333 |
Echinococcus multilocularis | protein jagged 2 | 0.0063 | 0.1395 | 0.1395 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0037 | 0.0606 | 0.0152 |
Brugia malayi | AMP-binding enzyme family protein | 0.0048 | 0.0935 | 0.1309 |
Brugia malayi | hypothetical protein | 0.0196 | 0.5363 | 0.7503 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0935 | 0.1309 |
Schistosoma mansoni | peroxidasin | 0.0196 | 0.5363 | 0.7503 |
Leishmania major | cathepsin L-like protease | 0.0064 | 0.1402 | 0.1649 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0037 | 0.0606 | 0.0848 |
Brugia malayi | EGF-like domain containing protein | 0.0063 | 0.1395 | 0.1951 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (functional) | = 90 uM | Antiplasmodial activity against Plasmodium falciparum assessed as inhibition of parasite LDH activity after 72 hrs | ChEMBL. | 21944972 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.